Base de dados : MEDLINE
Pesquisa : C08.127.930 [Categoria DeCS]
Referências encontradas : 173 [refinar]
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  1 / 173 MEDLINE  
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[PMID]:27367849
[Au] Autor:Kuwal A; Dutt N; Chauhan N; Kumar S; Purohit S; Saini LK
[Ad] Endereço:Department of Pulmonary Medicine, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
[Ti] Título:An Atypical Case of Mounier-Kuhn Syndrome: Time to Change the Diagnostic Approach?
[So] Source:J Bronchology Interv Pulmonol;24(1):84-87, 2017 Jan.
[Is] ISSN:1948-8270
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Mounier-Kuhn syndrome (MKS) is a rare disease of unknown etiology characterized by abnormal pathologic dilatation of tracheabronchial tree. The diagnosis of MKS is normally made on CT scan of chest on the basis of enlarged diameters of trachea and main stem bronchi. We are presenting histologically confirmed case of MKS, where the diameter of right main bronchus is below minimum diameter (mean+3 SD) required for the diagnosis. We suggest that the diagnosis of MKS should not be solely based on fixed criteria such as the diameter of airways, but on the basis of the overall clinical, pathologic, and radiologic profile.
[Mh] Termos MeSH primário: Broncoscopia/métodos
Síndrome de Marfan/complicações
Pneumonia Pneumocócica/diagnóstico
Traqueobroncomegalia/diagnóstico
[Mh] Termos MeSH secundário: Adulto
Antibacterianos/uso terapêutico
Broncodilatadores/uso terapêutico
Seres Humanos
Masculino
Modalidades de Fisioterapia
Pneumonia Pneumocócica/tratamento farmacológico
Streptococcus pneumoniae/isolamento & purificação
Tomografia Computadorizada por Raios X/métodos
Traqueobroncomegalia/diagnóstico por imagem
Traqueobroncomegalia/tratamento farmacológico
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); 0 (Bronchodilator Agents)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170530
[Lr] Data última revisão:
170530
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160702
[St] Status:MEDLINE


  2 / 173 MEDLINE  
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[PMID]:27607887
[Au] Autor:Hoffmann H; Gompelmann D; Heußel CP; Dienemann H; Eberhardt R
[Ad] Endereço:Chirurgische Abteilung, Thoraxklinik Universitätsklinikum Heidelberg, Deutschland.
[Ti] Título:[Tracheobronchoplasty for Severe Diffuse Tracheomalacia].
[Ti] Título:Tracheobronchoplastie bei schwerer diffuser Tracheobronchomalazie..
[So] Source:Zentralbl Chir;141 Suppl 1:S35-42, 2016 Sep.
[Is] ISSN:1438-9592
[Cp] País de publicação:Germany
[La] Idioma:ger
[Ab] Resumo:Patients with diffuse airway instability due to tracheobronchomalacia or excessive dynamic airway collapse are typically highly symptomatic, with marked dyspnoea, recurrent bronchopulmonary infections and excruciating intractable cough. Silicone stents achieve immediate symptom control, but are - due to the typical complications associated with stent treatment - usually not an option for long-term treatment. The aim of surgical intervention is definitive stabilisation of the trachea and of both main bronchi by posterior splinting of the Paries membranaceus with a polypropylene mesh. This operation is an appropriate treatment option for patients with documented severe tracheobronchomalacia or excessive dynamic airway collapse and is ultimately the only therapy that can achieve permanent symptom control. The success of the operation, however, depends on many factors and requires close interdisciplinary collaboration.
[Mh] Termos MeSH primário: Brônquios/cirurgia
Traqueia/cirurgia
Traqueobroncomalácia/cirurgia
[Mh] Termos MeSH secundário: Adulto
Idoso
Idoso de 80 Anos ou mais
Anastomose Cirúrgica
Broncoscopia
Feminino
Seguimentos
Seres Humanos
Masculino
Meia-Idade
Tireoidectomia
Tomografia Computadorizada por Raios X
Traqueobroncomalácia/diagnóstico
Traqueobroncomegalia/diagnóstico
Traqueobroncomegalia/cirurgia
[Pt] Tipo de publicação:JOURNAL ARTICLE; WEBCASTS
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160909
[St] Status:MEDLINE
[do] DOI:10.1055/s-0042-113193


  3 / 173 MEDLINE  
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[PMID]:27022925
[Au] Autor:Schmitt P; Dalar L; Jouneau S; Toublanc B; Camuset J; Chatte G; Cellerin L; Dutau H; Sanchez S; Sauvage M; Vergnon JM; Dury S; Deslée G; Lebargy F; Groupe d''Endoscopie de Langue Française (GELF)
[Ad] Endereço:Department of Respiratory Medicine, University Hospital Maison Blanche, Reims, France.
[Ti] Título:Respiratory Conditions Associated with Tracheobronchomegaly (Mounier-Kuhn Syndrome): A Study of Seventeen Cases.
[So] Source:Respiration;91(4):281-7, 2016.
[Is] ISSN:1423-0356
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Mounier-Kuhn syndrome (MKS) is a rare disorder characterized by enlargement of the trachea and main bronchi and associated with recurrent respiratory tract infections. OBJECTIVE: This multicenter, retrospective study was carried out to describe respiratory conditions associated with tracheobronchomegaly. METHODS: Nine institutions involved in the 'Groupe d'Endoscopie de Langue Française' (GELF) participated in this study. A standard form was used to record patient characteristics, treatments and follow-up from medical charts. RESULTS: Seventeen patients, 53% male, aged 58 ± 18 years at diagnosis were included. Recurrent infections revealed MKS in 88% of cases. Main comorbid conditions were diffuse bronchiectasis in 88% of patients and tracheobronchomalacia in 67% of cases. The exacerbation rate was 1.5 exacerbations/patient/year. The main non-respiratory morbid condition was gastroesophageal reflux disease in 29% of cases. Interventional bronchoscopy was performed in seven patients (41%), consisting of laser (n = 2) and tracheal stenting (n = 5). Complications related to stents were observed in 80% of cases with a mean stent duration of 8 months. Four deaths, including three due to respiratory causes, occurred during follow-up. CONCLUSIONS: This is the largest series of MKS reported in the literature, showing that bronchiectasis and tracheobronchomalacia are the main associated morbid conditions that constitute a challenge for treatment.
[Mh] Termos MeSH primário: Bronquiectasia/complicações
Enfisema Pulmonar/complicações
Traqueobroncomalácia/complicações
Traqueobroncomegalia/complicações
[Mh] Termos MeSH secundário: Adulto
Idade de Início
Idoso
Broncoscopia
Feminino
Refluxo Gastroesofágico/complicações
Seres Humanos
Masculino
Meia-Idade
Infecções Respiratórias/etiologia
Estudos Retrospectivos
Tomografia Computadorizada por Raios X
[Pt] Tipo de publicação:JOURNAL ARTICLE; MULTICENTER STUDY
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160330
[St] Status:MEDLINE
[do] DOI:10.1159/000445029


  4 / 173 MEDLINE  
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[PMID]:27007971
[Au] Autor:Casso G; Schoettker P
[Ad] Endereço:Cardiocentro Ticino, Lugano, Switzerland gabriele.casso@cardiocentro.org.
[Ti] Título:IMAGES IN CLINICAL MEDICINE. Tracheobronchomegaly.
[So] Source:N Engl J Med;374(12):e14, 2016 Mar 24.
[Is] ISSN:1533-4406
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Broncografia
Traqueia/diagnóstico por imagem
Traqueobroncomegalia/diagnóstico por imagem
[Mh] Termos MeSH secundário: Idoso de 80 Anos ou mais
Estenose da Valva Aórtica/complicações
Estenose da Valva Aórtica/cirurgia
Evolução Fatal
Seres Humanos
Masculino
Tomografia Computadorizada por Raios X
Traqueobroncomegalia/complicações
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1604
[Cu] Atualização por classe:161126
[Lr] Data última revisão:
161126
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:160324
[St] Status:MEDLINE
[do] DOI:10.1056/NEJMicm1508462


  5 / 173 MEDLINE  
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[PMID]:26791590
[Au] Autor:Adachi K; Umezaki T; Komune S
[Ad] Endereço:Department of Otorhinolaryngology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan. Electronic address: adakazu@qent.med.kyushu-u.ac.jp.
[Ti] Título:Tracheobronchomegaly associated with laryngo-tracheal amyloidosis: First case report.
[So] Source:Auris Nasus Larynx;43(4):472-5, 2016 Aug.
[Is] ISSN:1879-1476
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Tracheobronchomegaly (TBM) is a rare enlargement of the tracheal cartilage, also known as Mounier-Kuhn syndrome (MKS). Here, we describe an unusual case of acquired TBM in an adult, caused by amyloid regeneration and associated tracheal weakening, rather than by MKS. CT scan and fiberscopic examination of a 55-year-old woman suffering from severe dyspnea revealed TBM and subglottic stenosis, which was caused by deposition of amyloid tissue. We performed a tracheostomy and vaporized the subglottic stenosis with a CO2 laser, after which we installed a silicone T-tube. After the first operation, re-stenosis occurred, and the procedure was repeated; stenosis was subsequently cured and the dyspnea disappeared, after which the tracheostomy could be closed. This is the first report of adult TBM associated with amyloid deposition in the subglottis and trachea. This diagnosis is very difficult, as amyloid deposition in the trachea can have various clinical presentations.
[Mh] Termos MeSH primário: Amiloidose/patologia
Doenças da Laringe/patologia
Laringoestenose/diagnóstico por imagem
Doenças da Traqueia/patologia
Traqueobroncomegalia/diagnóstico por imagem
[Mh] Termos MeSH secundário: Amiloidose/complicações
Dispneia/etiologia
Feminino
Seres Humanos
Doenças da Laringe/complicações
Laringoestenose/etiologia
Laringoestenose/cirurgia
Lasers de Gás/uso terapêutico
Meia-Idade
Recidiva
Tomografia Computadorizada por Raios X
Doenças da Traqueia/complicações
Traqueobroncomegalia/etiologia
Traqueostomia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170227
[Lr] Data última revisão:
170227
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160122
[St] Status:MEDLINE


  6 / 173 MEDLINE  
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[PMID]:26127019
[Au] Autor:Unlu EN; Annakkaya AN; Balbay EG; Aydin LY; Safci S; Boran M; Guclu D
[Ad] Endereço:Department of Radiology, Faculty of Medicine, Duzce University, Duzce, Turkey. Electronic address: nisaunlu@yahoo.com.
[Ti] Título:An unusual cause of recurrent spontaneous pneumothorax: the Mounier-Kuhn syndrome.
[So] Source:Am J Emerg Med;34(1):122.e1-2, 2016 Jan.
[Is] ISSN:1532-8171
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:We present a case of 63-year-old man who was referred to the emergency department with a right-sided pneumothorax. He had a history of spontaneous pneumothorax for 2 times. The chest computed tomographic scan showed tracheobronchomegaly with an increase in the diameter of the trachea and right and left main bronchus. Fiberoptic bronchoscopy revealed enlarged trachea and both main bronchus with diverticulas. These findings are consistent with a diagnosis of Mounier-Kuhn syndrome. Mounier-Kuhn syndrome is a rare clinical and radiologic condition. It is characterized by a tracheal and bronchial dilation. Diagnosis is made by computed tomography and bronchoscopy. Mounier-Kuhn syndrome should be kept in mind in the differential diagnosis of recurrent spontaneous pneumothorax.
[Mh] Termos MeSH primário: Pneumotórax/diagnóstico
Pneumotórax/etiologia
Traqueobroncomegalia/complicações
Traqueobroncomegalia/diagnóstico
[Mh] Termos MeSH secundário: Broncoscopia
Diagnóstico Diferencial
Seres Humanos
Masculino
Meia-Idade
Recidiva
Tomografia Computadorizada por Raios X
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1604
[Cu] Atualização por classe:151217
[Lr] Data última revisão:
151217
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150702
[St] Status:MEDLINE


  7 / 173 MEDLINE  
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[PMID]:25130790
[Au] Autor:Krustins E
[Ad] Endereço:Department of Internal Medicine, Pauls Stradins Clinical University Hospital, Riga, Latvia.
[Ti] Título:Mounier-Kuhn syndrome: a systematic analysis of 128 cases published within last 25 years.
[So] Source:Clin Respir J;10(1):3-10, 2016 Jan.
[Is] ISSN:1752-699X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND AND AIMS: Mounier-Kuhn syndrome is a rare disease with abnormal enlargement of major airways, but epidemiological studies are lacking, and currently the most available data about it come from case reports, making it difficult to collate changes in a particular patient to those in previously published cases. The aim of this work is to systematically review cases published in the last 25 years and to use descriptive statistics to summarize the patient demographic and clinical information therein in order to acquire details about patient clinical characteristics. METHODS: Cases published in world literature between 1987 and 2013 were sought and reviewed according to PRISMA guidelines. Cases were included only if patient's age was at least 18 years, and a computed tomography scan with tracheal measurements was available. RESULTS: An 8:1 male predominance was found in 89 identified reports (128 cases). Mean age was 53.9 years, and average tracheal diameter was 36.1 mm. No correlation between increasing age and increasing tracheal diameter was found. Bronchiectasis, tracheal diverticulosis and tracheobronchial dyskinesia were common (49.2%, 33.6% and 28.9%, respectively). Cough, dyspnea and recurrent respiratory infections (71.1%, 51.6% and 50.8%, respectively) were the most common complaints. CONCLUSIONS: The data confirm that syndrome mostly manifests with nonspecific respiratory symptoms and is significantly more common in males. Importantly, there was no connection between age and airway diameter, a fact that could mean that the enlargement does not progress over time, and its severity depends on some other yet undetermined factors.
[Mh] Termos MeSH primário: Traqueobroncomegalia/patologia
[Mh] Termos MeSH secundário: Adulto
Idoso
Doença Crônica
Demografia
Feminino
Seres Humanos
Masculino
Meia-Idade
Doenças Raras
Espirometria
Traqueobroncomegalia/complicações
Traqueobroncomegalia/diagnóstico por imagem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T; REVIEW
[Em] Mês de entrada:1611
[Cu] Atualização por classe:170103
[Lr] Data última revisão:
170103
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140819
[St] Status:MEDLINE
[do] DOI:10.1111/crj.12192


  8 / 173 MEDLINE  
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[PMID]:26591972
[Au] Autor:Singh M; Kumar R
[Ti] Título:A 54-Year-Old Man with Tracheomegaly, Tracheal Diverticulas and Bronchiectasis--Mounier-Kuhn Syndrome.
[So] Source:Indian J Chest Dis Allied Sci;57(2):113-5, 2015 Apr-Jun.
[Is] ISSN:0377-9343
[Cp] País de publicação:India
[La] Idioma:eng
[Ab] Resumo:Mounier-Kuhn syndrome is a rare idiopathic clinical, radiological and bronchoscopic disorder characterised by abnormal dilatation of the tracheo-bronchial tree. The usual presentation is with recurrent lower respiratory tract infections. Herein, we report the case of an adult male who was diagnosed to have Mounier-Kuhn syndrome based on radiographic finding of a tracheal diameter of 45.5 mm on computed tomography and dynamic complete collapse of the tracheo-bronchial tree on forced expiration, observed during ronchoscopy.
[Mh] Termos MeSH primário: Bronquiectasia/diagnóstico
Divertículo/diagnóstico
Traqueobroncomegalia/diagnóstico
[Mh] Termos MeSH secundário: Bronquiectasia/complicações
Divertículo/complicações
Seres Humanos
Masculino
Meia-Idade
Espirometria
Doenças da Traqueia/complicações
Doenças da Traqueia/diagnóstico
Traqueobroncomegalia/complicações
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1512
[Cu] Atualização por classe:151123
[Lr] Data última revisão:
151123
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151124
[St] Status:MEDLINE


  9 / 173 MEDLINE  
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[PMID]:26189148
[Au] Autor:Payandeh J; McGillivray B; McCauley G; Wilcox P; Swiston JR; Lehman A
[Ad] Endereço:Department of Medical Genetics, University of British Columbia, C234-4500 Oak Street, Vancouver, BC, V6H 3N1, Canada.
[Ti] Título:A Clinical Classification Scheme for Tracheobronchomegaly (Mounier-Kuhn Syndrome).
[So] Source:Lung;193(5):815-22, 2015 Oct.
[Is] ISSN:1432-1750
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: Tracheobronchomegaly (Mounier-Kuhn Syndrome) is a rare disease characterized by tracheal enlargement and associated loss of elastic fibers in the trachea and main bronchi. MATERIALS: MEDLINE, Index Medicus, and other databases were searched with pre-defined criteria to identify cases of tracheobronchomegaly (TBM). Two new cases of TBM were also identified from the Provincial Medical Genetics Program of British Columbia. RESULTS: We identified 166 publications describing 365 occurrences of TBM. We observed that affected individuals could be grouped into subgroups according to clinical features. Type 1A (105 individuals) consists of infants who developed TBM after having undergone fetoscopic tracheal occlusion, and Type 1B patients (24 individuals) are infants and children who developed TBM after prolonged intubation. Type 2 individuals developed TBM following recurrent pulmonary infections (2A) (14 individuals) or pulmonary fibrosis (2B) (10 individuals). Type 3 represents TBM with evidence of extra-pulmonary elastolysis (18 individuals), and Type 4 denotes the development of TBM with no clear predisposing factors (196 individuals). Both of our patients had TBM and evidence of extra-pulmonary elastolysis. As well, one patient had a mildly dilated aortic root, which is a previously unreported co-occurrence. CONCLUSION: We introduce a novel classification scheme, which may sort patients into etiologically distinct groups, furthering our understanding of its pathogenesis and potentially, prevention or therapy. We also hypothesize that TBM and generalized elastolysis may have etiological commonalities, suggesting a need for further study.
[Mh] Termos MeSH primário: Traqueobroncomegalia/classificação
Traqueobroncomegalia/etiologia
[Mh] Termos MeSH secundário: Cútis Laxa/complicações
Fetoscopia/efeitos adversos
Seres Humanos
Lactente
Intubação Intratraqueal/efeitos adversos
Masculino
Meia-Idade
Fibrose Pulmonar/complicações
Infecções Respiratórias/complicações
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T; REVIEW
[Em] Mês de entrada:1607
[Cu] Atualização por classe:170928
[Lr] Data última revisão:
170928
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150720
[St] Status:MEDLINE
[do] DOI:10.1007/s00408-015-9757-z


  10 / 173 MEDLINE  
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[PMID]:26038962
[Au] Autor:Sailer S; Osona B; Peña-Zarza JA; Gil-Sanchez JA; Lacruz-Perez L; Mulet JF
[Ad] Endereço:Department of Pediatrics, University Hospital Son Espases, Palma de Mallorca, Spain.
[Ti] Título:Coincidence of Tracheobronchomegaly (Mounier-Kuhn Syndrome) and Juvenile Idiopathic Arthritis.
[So] Source:Klin Padiatr;227(5):290-2, 2015 Sep.
[Is] ISSN:1439-3824
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:Mounier-Kuhn syndrome (MKS) or tracheobronchomegaly includes clinical and radiographic findings of tracheobronchial dilatation and recurrent respiratory infections. MKS is a very rare pathology, especially in the paediatric age group which makes it a diagnostic challenge. A 4-year-old girl suffered from dyspnea, recurrent respiratory infections and joint pain. Chest radiography detected peribronchial reinforcement and CT-scan revealed extended tracheal dilatation and bronchiectasis. In addition to MKS our patient was diagnosed with juvenile idiopathic arthritis (JIA) and scleroderma. MKS can be caused by congenital disorder or acquired aetiology. Several connective tissue diseases have been associated with MKS but no cases of JIA or scleroderma are described previously. Our case illustrates that patients who suffer from recurrent respiratory infections with unsatisfactory evolution and unspecific chest X-ray alteration, MKS always has to be considered in the differential diagnosis particularly in patients who suffer from connective tissue diseases.
[Mh] Termos MeSH primário: Artrite Juvenil/complicações
Artrite Juvenil/epidemiologia
Traqueobroncomegalia/complicações
Traqueobroncomegalia/epidemiologia
[Mh] Termos MeSH secundário: Artralgia/etiologia
Artrite Juvenil/diagnóstico
Pré-Escolar
Diagnóstico Diferencial
Dispneia/etiologia
Feminino
Seres Humanos
Recidiva
Infecções Respiratórias/etiologia
Esclerodermia Localizada/complicações
Esclerodermia Localizada/epidemiologia
Tomografia Computadorizada por Raios X
Traqueobroncomegalia/diagnóstico
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1608
[Cu] Atualização por classe:150909
[Lr] Data última revisão:
150909
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150604
[St] Status:MEDLINE
[do] DOI:10.1055/s-0035-1548837



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