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[PMID]:29291277
[Au] Autor:Ahmad I; Kirby P; Liming B
[Ad] Endereço:1 Division of Pediatric Otolaryngology, Department of Otolaryngology-Head and Neck Surgery, Stanford University, Palo Alto, California, USA.
[Ti] Título:Ectopic Thymic Cyst of the Subglottis: Considerations for Diagnosis and Management.
[So] Source:Ann Otol Rhinol Laryngol;127(3):200-204, 2018 Mar.
[Is] ISSN:1943-572X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: To share the diagnostic and management challenges created by an extremely rare airway lesion-the subglottic ectopic thymic cyst. STUDY DESIGN: Case report and literature review. METHODS: We review the presentation, management, and clinical course of an infant who presented with a subglottic mass that was histologically confirmed as a thymic cyst. A brief literature review supplements the case presentation Results: We present the third described case of an ectopic thymic cyst presenting as a subglottic mass. The differential diagnosis of subglottic masses in neonates consists primarily of subglottic hemangioma and mucous retention cysts. Otolaryngologists must be prepared for unexpected findings when dealing with critical airways. We compare the presentation and management of our patient with the 2 previously described cases. We propose an embryologic theory for the origin of these rare lesions. CONCLUSIONS: An ectopic thymic cyst is a rare and unexpected cause of neonatal stridor. Management of pediatric airway lesions must allow for unexpected findings at the time of diagnostic and therapeutic endoscopy. The appropriate management of subglottic thymic cysts is poorly defined, but close surveillance for recurrence is mandatory.
[Mh] Termos MeSH primário: Anormalidades Congênitas/diagnóstico
Doenças da Laringe
Laringoscopia/métodos
Laringe/anormalidades
Cisto Mediastínico
Sons Respiratórios/diagnóstico
[Mh] Termos MeSH secundário: Coristoma
Anormalidades Congênitas/etiologia
Diagnóstico Diferencial
Seres Humanos
Lactente
Doenças da Laringe/diagnóstico
Doenças da Laringe/fisiopatologia
Masculino
Sons Respiratórios/etiologia
Resultado do Tratamento
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180221
[Lr] Data última revisão:
180221
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180102
[St] Status:MEDLINE
[do] DOI:10.1177/0003489417749609


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[PMID]:29365380
[Au] Autor:Li LJ; Du C; Wang L; Yan Y; Zeng J; Xu CY; Sun SL
[Ad] Endereço:Department of Otorhinolaryngology Head and Neck Surgery, Peking University Third Hospital, Beijing 100191, China.
[Ti] Título:[Application of endoscope assisted curved laryngoscopy technique in transoral laryngopharyngeal minimally invasive surgery].
[So] Source:Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi;53(1):45-48, 2018 Jan 07.
[Is] ISSN:1673-0860
[Cp] País de publicação:China
[La] Idioma:chi
[Ab] Resumo:To explore the possibility of endoscope assisted curved laryngoscopy technique applied in transoral laryngopharyngeal minimally invasive surgery and evaluate the advantages of this technique. Eight patients with huge benign lesions in larynx and pharynx undergoing transoral microsurgery at Peking University Third Hospital between February 2016 and February 2017 were enrolled in this study.The diagnosis included cyst at the base of tongue in two patients, cysts in the epiglottis in two patients, hemangioma in two patients, multiple masses of the hypopharynx and amyloidosis in supraglottic area in one patient each.The time and exposure during surgery, occurrence rate of complication and conditions of following-up were recorded. The mean time of surgery was 20 min, the exposure was satisfying.There was no obvious complication after surgery.No residual or recurrent lesion was observed after 1 to 12 months follow-up(mean time 4.5 months). The endoscope assisted curved laryngoscopy technique has advantages in shortening the time of surgery, improving exposure and reducing the rate of complication and recurrence.
[Mh] Termos MeSH primário: Doenças da Laringe/cirurgia
Laringoscópios
Laringoscopia/instrumentação
Laringoscopia/métodos
[Mh] Termos MeSH secundário: Amiloidose/cirurgia
Cistos/cirurgia
Epiglote/cirurgia
Desenho de Equipamento
Hemangioma/cirurgia
Seres Humanos
Hipofaringe/cirurgia
Microcirurgia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180215
[Lr] Data última revisão:
180215
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180125
[St] Status:MEDLINE
[do] DOI:10.3760/cma.j.issn.1673-0860.2018.01.010


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[PMID]:29241348
[Au] Autor:Kim M; Sadoughi B
[Ad] Endereço:1 Sean Parker Institute for the Voice, Department of Otolaryngology-Head and Neck Surgery, Weill Cornell Medical College/NewYork-Presbyterian Hospital, New York, New York, USA.
[Ti] Título:The Voice of Autoimmunity: Antisynthetase Syndrome Manifesting as Vocal Fold Bamboo Nodes.
[So] Source:Ann Otol Rhinol Laryngol;127(2):128-130, 2018 Feb.
[Is] ISSN:1943-572X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: To describe a case of vocal fold bamboo nodes leading to the diagnosis of antisynthetase syndrome, a rare autoimmune disorder. To highlight the link between these laryngeal lesions and autoimmunity. METHODS: A case of vocal fold bamboo nodes in a patient with long-standing interstitial lung disease is presented. The presence of these characteristic lesions prompted a rheumatologic workup that led to the diagnosis of a rare autoimmune disorder. RESULTS: The patient was ultimately diagnosed with antisynthetase syndrome, a rare condition characterized by inflammatory myositis and interstitial lung disease. She was treated with steroids and immunosuppressive agents with improvement in her symptoms and clinical findings. CONCLUSIONS: Vocal fold bamboo nodes are pathognomonic signs of autoimmunity. Management consists primarily of medical treatment of the underlying systemic disorder. Intralesional steroid injection or phonomicrosurgical excision may be considered for refractory cases.
[Mh] Termos MeSH primário: Doenças Autoimunes/diagnóstico
Disfonia/diagnóstico
Doenças da Laringe/diagnóstico
Doenças Pulmonares Intersticiais/diagnóstico
Doença Mista do Tecido Conjuntivo/diagnóstico
Miosite/diagnóstico
Nódulo Reumatoide/diagnóstico
Prega Vocal/patologia
[Mh] Termos MeSH secundário: Doenças Autoimunes/tratamento farmacológico
Diagnóstico Diferencial
Disfonia/tratamento farmacológico
Disfonia/patologia
Feminino
Seres Humanos
Doenças da Laringe/tratamento farmacológico
Doenças da Laringe/patologia
Laringoscopia
Doenças Pulmonares Intersticiais/tratamento farmacológico
Doenças Pulmonares Intersticiais/patologia
Meia-Idade
Doença Mista do Tecido Conjuntivo/tratamento farmacológico
Miosite/tratamento farmacológico
Prednisona/uso terapêutico
Nódulo Reumatoide/tratamento farmacológico
Nódulo Reumatoide/patologia
Gravação em Vídeo
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
VB0R961HZT (Prednisone)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180123
[Lr] Data última revisão:
180123
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171216
[St] Status:MEDLINE
[do] DOI:10.1177/0003489417748331


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[PMID]:29231041
[Au] Autor:Carroll TL; Dezube A; Bauman LA; Mallur PS
[Ad] Endereço:1 Department of Otolaryngology, Harvard Medical School, Department of Surgery, Brigham and Women's Hospital, Boston, Massachusetts, USA.
[Ti] Título:Using Trial Vocal Fold Injection to Select Vocal Fold Scar Patients Who May Benefit From More Durable Augmentation.
[So] Source:Ann Otol Rhinol Laryngol;127(2):105-112, 2018 Feb.
[Is] ISSN:1943-572X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: Clinical indications for vocal fold injection augmentation (VFI) are expanding. Prior studies demonstrate the benefit of trial VFI for select causes of glottic insufficiency. No studies have examined trial VFI for glottic insufficiency resulting from true vocal fold (TVF) scar. METHODS: Retrospective chart review of patients who underwent trial VFI for a dominant pathology of TVF scar causing dysphonia. Patients who subsequently underwent durable augmentation were identified. The primary study outcome was the difference in Voice Handicap Index-10 (VHI-10) score from pretrial VFI to post-durable augmentation. RESULTS: Twenty-eight patients underwent trial VFI for TVF scar, 22 of whom reported a positive response. Fifteen of 22 subjects who underwent durable augmentation had viable data for analysis. Mean VHI-10 improved from 26.9 to 18.6 ( P < .05), for a delta VHI-10 of 8.3, or 30.9% improvement. Twelve of the 15 (80%) showed a clinically significant improvement (delta VHI-10 >5). CONCLUSIONS: A trial VFI is a potentially useful, low-risk procedure that appears to help the patient and clinician identify when global augmentation might improve the voice when vocal fold scar is present. Patients who reported successful trial VFI often demonstrated significant improvement in their VHI-10 after subsequent durable augmentation.
[Mh] Termos MeSH primário: Carboximetilcelulose Sódica/administração & dosagem
Cicatriz/terapia
Disfonia/terapia
Doenças da Laringe/terapia
Prega Vocal
[Mh] Termos MeSH secundário: Adulto
Idoso
Idoso de 80 Anos ou mais
Cicatriz/complicações
Disfonia/etiologia
Feminino
Seguimentos
Seres Humanos
Injeções
Masculino
Meia-Idade
Satisfação do Paciente
Estudos Retrospectivos
Qualidade da Voz
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
K679OBS311 (Carboxymethylcellulose Sodium)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180123
[Lr] Data última revisão:
180123
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171213
[St] Status:MEDLINE
[do] DOI:10.1177/0003489417746188


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[PMID]:29199444
[Au] Autor:Hoffman HT; Stegall H; Wingler T; Blitzer A
[Ad] Endereço:1 Department of Otolaryngology, University of Iowa, Iowa City, Iowa, USA.
[Ti] Título:Steering Sheath for 2-Nostril Transnasal Office Laryngoscopy.
[So] Source:Ann Otol Rhinol Laryngol;127(2):99-104, 2018 Feb.
[Is] ISSN:1943-572X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: The aim was to study the feasibility of performing office-based laryngeal procedures employing a flexible hollow steerable sheath placed contralateral to the nostril through which a standard flexible video endoscope is placed. METHODS: The study design included simulation of transnasal endoscopic laryngeal procedures evaluating the use of a flexible steering sheath in laboratory and clinic settings. Transnasal laryngeal procedures were performed in an otolaryngology office setting employing an airway-management-trainer mannequin and then repeated in a human cadaver lab with standard transnasal flexible video laryngoscopy. Video documentation assessed use of a lever-manipulated deflecting ureteral access sheath with an inner diameter of 2.97 mm, an outer diameter of 4.95 mm, and a length of 45 cm. Simulated transnasal laryngoscopy procedures deployed devices through the deflecting sheath to mimic vocal fold needle injection, biopsy with forceps, balloon dilation, and laser treatment to identify strengths and shortcomings to the technology and technique. RESULTS: Simulation was successful in appropriately directing instrumentation for all procedures tested. Shortcomings included limitations in steering capacity, greater length to the sheath than desirable for laryngeal procedures, and the need for additional assistants to perform procedures. CONCLUSION: Steering sheath technology is applicable to enhance in-office transnasal laryngoscopy procedures.
[Mh] Termos MeSH primário: Desenho de Equipamento
Laringoscopia/instrumentação
Consultórios Médicos
Gravação em Vídeo/instrumentação
[Mh] Termos MeSH secundário: Biópsia/instrumentação
Cadáver
Dilatação/instrumentação
Seres Humanos
Injeções/instrumentação
Doenças da Laringe/diagnóstico
Doenças da Laringe/terapia
Manequins
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180124
[Lr] Data última revisão:
180124
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171205
[St] Status:MEDLINE
[do] DOI:10.1177/0003489417745091


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[PMID]:29219190
[Au] Autor:Blitzer A; Brin MF; Simonyan K; Ozelius LJ; Frucht SJ
[Ad] Endereço:Department of Otolaryngology-Head and Neck Surgery, Columbia University, College of Physicians and Surgeons, New York, New York.
[Ti] Título:Phenomenology, genetics, and CNS network abnormalities in laryngeal dystonia: A 30-year experience.
[So] Source:Laryngoscope;128 Suppl 1:S1-S9, 2018 Jan.
[Is] ISSN:1531-4995
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: Laryngeal dystonia (LD) is a functionally specific disorder of the afferent-efferent motor coordination system producing action-induced muscle contraction with a varied phenomenology. This report of long-term studies aims to review and better define the phenomenology and central nervous system abnormalities of this disorder and improve diagnosis and treatment. METHODS: Our studies categorized over 1,400 patients diagnosed with LD over the past 33 years, including demographic and medical history records and their phenomenological presentations. Patients were grouped on clinical phenotype (adductor or abductor) and genotype (sporadic and familial) and with DNA analysis and functional magnetic resonance imaging (fMRI) to investigate brain organization differences and characterize neural markers for genotype/phenotype categorization. A number of patients with alcohol-sensitive dystonia were also studied. RESULTS: A spectrum of LD phenomena evolved: adductor, abductor, mixed, singer's, dystonic tremor, and adductor respiratory dystonia. Patients were genetically screened for DYT (dystonia) 1, DYT4, DYT6, and DYT25 (GNAL)-and several were positive. The functional MRI studies showed distinct alterations within the sensorimotor network, and the LD patients with a family history had distinct cortical and cerebellar abnormalities. A linear discriminant analysis of fMRI findings showed a 71% accuracy in characterizing LD from normal and in characterizing adductor from abductor forms. CONCLUSION: Continuous studies of LD patients over 30 years has led to an improved understanding of the phenomenological characteristics of this neurological disorder. Genetic and fMRI studies have better characterized the disorder and raise the possibility of making objective rather than subjective diagnoses, potentially leading to new therapeutic approaches. Laryngoscope, 128:S1-S9, 2018.
[Mh] Termos MeSH primário: Sistema Nervoso Central/anormalidades
Distúrbios Distônicos/genética
Distúrbios Distônicos/fisiopatologia
Doenças da Laringe/genética
Doenças da Laringe/fisiopatologia
[Mh] Termos MeSH secundário: Mapeamento Encefálico
Sistema Nervoso Central/diagnóstico por imagem
Genótipo
Seres Humanos
Imagem por Ressonância Magnética
Fenótipo
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180109
[Lr] Data última revisão:
180109
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171209
[St] Status:MEDLINE
[do] DOI:10.1002/lary.27003


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[PMID]:28949246
[Au] Autor:de la Fuente J; Garrett CG; Ossoff R; Vinson K; Francis DO; Gelbard A
[Ad] Endereço:1 Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA.
[Ti] Título:A Case Series of the Probability Density and Cumulative Distribution of Laryngeal Disease in a Tertiary Care Voice Center.
[So] Source:Ann Otol Rhinol Laryngol;126(11):748-754, 2017 Nov.
[Is] ISSN:1943-572X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To examine the distribution of clinic and operative pathology in a tertiary care laryngology practice. METHODS: Probability density and cumulative distribution analyses (Pareto analysis) was used to rank order laryngeal conditions seen in an outpatient tertiary care laryngology practice and those requiring surgical intervention during a 3-year period. RESULTS: Among 3783 new clinic consultations and 1380 operative procedures, voice disorders were the most common primary diagnostic category seen in clinic (n = 3223), followed by airway (n = 374) and swallowing (n = 186) disorders. Within the voice strata, the most common primary ICD-9 code used was dysphonia (41%), followed by unilateral vocal fold paralysis (UVFP) (9%) and cough (7%). Among new voice patients, 45% were found to have a structural abnormality. The most common surgical indications were laryngotracheal stenosis (37%), followed by recurrent respiratory papillomatosis (18%) and UVFP (17%). CONCLUSIONS: Nearly 55% of patients presenting to a tertiary referral laryngology practice did not have an identifiable structural abnormality in the larynx on direct or indirect examination. The distribution of ICD-9 codes requiring surgical intervention was disparate from that seen in clinic. Application of the Pareto principle may improve resource allocation in laryngology, but these initial results require confirmation across multiple institutions.
[Mh] Termos MeSH primário: Doenças da Laringe/diagnóstico
Doenças da Laringe/cirurgia
Atenção Terciária à Saúde
[Mh] Termos MeSH secundário: Efeitos Psicossociais da Doença
Tosse/diagnóstico
Tosse/cirurgia
Disfonia/diagnóstico
Disfonia/cirurgia
Seres Humanos
Laringoestenose/diagnóstico
Laringoestenose/cirurgia
Papiloma/diagnóstico
Papiloma/cirurgia
Neoplasias do Sistema Respiratório/diagnóstico
Neoplasias do Sistema Respiratório/cirurgia
Tennessee
Centros de Atenção Terciária
Estenose Traqueal/diagnóstico
Estenose Traqueal/cirurgia
Paralisia das Pregas Vocais/diagnóstico
Paralisia das Pregas Vocais/cirurgia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171031
[Lr] Data última revisão:
171031
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170927
[St] Status:MEDLINE
[do] DOI:10.1177/0003489417728945


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[PMID]:28895450
[Au] Autor:Mori MC; Francis DO; Song PC
[Ad] Endereço:1 Department of Otolaryngology-Head and Neck Surgery, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
[Ti] Título:Identifying Occupations at Risk for Laryngeal Disorders Requiring Specialty Voice Care.
[So] Source:Otolaryngol Head Neck Surg;157(4):670-675, 2017 Oct.
[Is] ISSN:1097-6817
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Objective To identify occupational groups' use of specialty voice clinic evaluation. Study Design Retrospective cohort study. Setting Tertiary subspecialty clinic. Subjects and Methods We analyzed data collected on patients presenting to the Massachusetts Eye and Ear Infirmary Voice and Speech Laboratory over a 20-year period (1993-2013). The relative risk (RR) and 99% confidence interval (CI) of presentation were calculated for each occupational category in the greater Boston population using year-matched data from the Bureau of Labor Statistics (BLS). Results The records of 12,120 new patients were reviewed. Using year- and occupation-matched BLS data from 2005 to 2013, 2726 patients were included in the cohort analysis. Several occupations had significantly higher risk of presentation. These included arts and entertainment (RR 4.98, CI 4.18-5.95), law (RR 3.24, CI 2.48-4.23), education (RR 3.08, CI 2.70-3.52), and social services (RR 2.07, CI 1.57-2.73). In contrast, many occupations had significantly reduced risk of presentation for laryngological disorders, for example, maintenance (RR 0.25, CI 0.15-0.42), food preparation (RR 0.35, CI 0.26-0.48), and administrative support (RR 0.49, CI 0.41-0.57). Conclusion Certain occupations are associated with higher use of laryngological services presumably because of their vocational voice needs. In addition to confirming findings from other studies, we identified several new occupation groups with increased or decreased risk for laryngologic disorders. Understanding what factors predispose to requiring specialty voice evaluation may help in targeting preventative efforts.
[Mh] Termos MeSH primário: Doenças da Laringe/epidemiologia
Doenças Profissionais/epidemiologia
Saúde do Trabalhador
Ocupações
Medição de Risco/métodos
Qualidade da Voz
[Mh] Termos MeSH secundário: Adulto
Idoso
Feminino
Seguimentos
Seres Humanos
Doenças da Laringe/diagnóstico
Doenças da Laringe/fisiopatologia
Masculino
Massachusetts/epidemiologia
Meia-Idade
Doenças Profissionais/diagnóstico
Doenças Profissionais/fisiopatologia
Ocupações/classificação
Prevalência
Estudos Retrospectivos
Fatores de Risco
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171012
[Lr] Data última revisão:
171012
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170913
[St] Status:MEDLINE
[do] DOI:10.1177/0194599817726528


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[PMID]:28806114
[Au] Autor:Tóbiás Z; Pálinkó D; Sztanó B; Csanády M; Gál P; Rovó L
[Ad] Endereço:Fül-Orr-Gégészeti és Fej-Nyak Sebészeti Klinika, Szegedi Tudományegyetem, Általános Orvostudományi Kar Szeged.
[Ti] Título:[Endoscopic ultra dream pulse laser surgery of laryngomalacia. Our experiences gained during the introduction of the method in Hungary].
[Ti] Título:A laryngomalacia endoszkópos ultrapulzációs-lézeres (ultra dream pulse) sebészete. A módszer hazai bevezetése során szerzett tapasztalataink..
[So] Source:Orv Hetil;158(33):1288-1292, 2017 Aug.
[Is] ISSN:0030-6002
[Cp] País de publicação:Hungary
[La] Idioma:hun
[Ab] Resumo:INTRODUCTION: Congenital stridor and dyspnoe are caused by laryngomalacia in most cases. AIM: In this article we present a new, surgical method for treating severe laryngomalacia in patients under the age of 1, where ultrapulsated (UDP) laser beam is used for supraglottoplasty. Ultra dream pulse laser creates lesser thermical side damage in the tissue, therefore the risk of postoperative laryngeal oedema and scarring is lower. METHOD: We present 10 cases and the endoscopic UDP-laser surgery of patients under the age of 1 with severe laryngomalacia. RESULTS: After the surgery the stridorous symptoms disappeared, and there was no evidence of postoperative laryngeal oedema, there was no need for reoperation or tracheotomy in any of the cases. CONCLUSION: UDP-laser surgery of laryngomalacia is proven to be a safe and effective surgial modality. During the follow up visits we experienced neither recurrence of stridor nor laryngeal scarring. Orv Hetil. 2017; 158(33): 1288-1292.
[Mh] Termos MeSH primário: Endoscopia/métodos
Doenças da Laringe/cirurgia
Terapia com Luz de Baixa Intensidade/métodos
[Mh] Termos MeSH secundário: Feminino
Seres Humanos
Lactente
Recém-Nascido
Masculino
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170928
[Lr] Data última revisão:
170928
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170815
[St] Status:MEDLINE
[do] DOI:10.1556/650.2017.30722


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[PMID]:28681923
[Au] Autor:Sachs AM; Bielamowicz SA; Stager SV
[Ad] Endereço:The George Washington University School of Medicine, Washington, DC.
[Ti] Título:Treatment effectiveness for aging changes in the larynx.
[So] Source:Laryngoscope;127(11):2572-2577, 2017 Nov.
[Is] ISSN:1531-4995
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: To compare the effectiveness of injection augmentation and bilateral thyroplasty surgery in managing age-related changes of the larynx. STUDY DESIGN: Retrospective chart review of patients treated with bilateral thyroplasty and/or injection augmentation. METHODS: We evaluated 22 patients before and after treatment using: 1) normalized glottal gap area and normalized true vocal fold width from endoscopic images; 2) patient self-rating questionnaires; and 3) acoustic and aerodynamic measures. RESULTS: Thyroplasty surgery resulted in 38% of patients demonstrating less bowing compared to 33% after injection, and 63% demonstrated less supraglottic activity compared to 43% after injection (P = 0.09). Change in mean Voice-Related Quality of Life (V-RQOL) scores was 25.5 after thyroplasty compared to -16.4 after injection (P < 0.05). Those exhibiting a greater than 20 change in V-RQOL after treatment were significantly more likely to report swallowing symptoms pretreatment. CONCLUSION: Patients postinjection did not rate themselves on any questionnaires as significantly better compared to pretreatment, whereas patients post-thyroplasty rated themselves as significantly improved on all questionnaires. Patients post-thyroplasty rated their voices as significantly closer to their best voice than patients postinjection. Likewise, 64% of patients who had thyroplasty surgery reported a significant treatment effect compared to 33% for injection augmentation. LEVEL OF EVIDENCE: 4. Laryngoscope, 127:2572-2577, 2017.
[Mh] Termos MeSH primário: Envelhecimento/fisiologia
Doenças da Laringe/fisiopatologia
Doenças da Laringe/terapia
Laringe/fisiologia
[Mh] Termos MeSH secundário: Fatores Etários
Idoso
Idoso de 80 Anos ou mais
Feminino
Seres Humanos
Injeções
Laringoplastia
Laringoscopia
Masculino
Meia-Idade
Qualidade de Vida
Estudos Retrospectivos
Inquéritos e Questionários
Resultado do Tratamento
Prega Vocal/fisiopatologia
Qualidade da Voz
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171030
[Lr] Data última revisão:
171030
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170707
[St] Status:MEDLINE
[do] DOI:10.1002/lary.26706



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