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[PMID]:29231008
[Au] Autor:Zeng Y; Ma JL; Chen L
[Ad] Endereço:Department of Forensic Medicine, Shanghai Medical College, Fudan University, Shanghai 200032, China.
[Ti] Título:[Significance of Hypoxia-related microRNA for Estimating the Cause of Mechanical Asphyxia Death].
[So] Source:Fa Yi Xue Za Zhi;33(1):38-41, 2017 Feb.
[Is] ISSN:1004-5619
[Cp] País de publicação:China
[La] Idioma:chi
[Ab] Resumo:Under hypoxia condition, microRNA (miRNA) can interact with transcription factors for regulating the cell metabolism, angiogenesis, erythropoiesis, cellular proliferation, differentiation and apoptosis. The biological processes above may play an important role in mechanical asphyxia death. This article reviews the regulating function of miRNA under hypoxia condition and the influence of hypoxia to biosynthesis of miRNA, which may provide some new ideas to the research of miRNA on determining the cause of mechanical asphyxia death in the field of forensic medicine.
[Mh] Termos MeSH primário: Acidentes
Obstrução das Vias Respiratórias/fisiopatologia
Asfixia/patologia
Hipóxia/genética
MicroRNAs/genética
[Mh] Termos MeSH secundário: Apoptose
Asfixia/mortalidade
Causas de Morte
Morte
Medicina Legal
Seres Humanos
Hipóxia/metabolismo
Hipóxia/fisiopatologia
MicroRNAs/metabolismo
Oxigênio
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (MicroRNAs); S88TT14065 (Oxygen)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180306
[Lr] Data última revisão:
180306
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171213
[St] Status:MEDLINE
[do] DOI:10.3969/j.issn.1004-5619.2017.01.010


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[PMID]:29268637
[Au] Autor:Melani AS; Lanzarone N; Rottoli P
[Ad] Endereço:a Fisiopatologia e Riabilitazione Respiratoria, Dipartimento Vasi, Cuore e Torace, Policlinico Le Scotte , Azienda Ospedaliera Universitaria Senese , Siena , Italy.
[Ti] Título:The pharmacological treatment of bronchiectasis.
[So] Source:Expert Rev Clin Pharmacol;11(3):245-258, 2018 Mar.
[Is] ISSN:1751-2441
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: Until recently considered as a minor health problem, the role of bronchiectasis is now increasingly recognized. New specific drugs are being approved for treatment of bronchiectasis. Possibly they will offer better perspectives to bronchiectatic subjects with evolving course. Areas covered: We provide an overview of aetiopathogenesis, clinics and non-pharmacological management, extending the topic of pharmacological treatment. Present therapies were extrapolated from other chronic lung diseases, but newer promising specific drugs are being awaited. Therapy aims at improving mobilisation of bronchial secretions and, if any, reversing airflow obstruction. Antibiotics are indicated to treat exacerbations, eradicate or reduce sputum bacterial load. Expert commentary: Over the last years evidence is mounted that bronchiectatic subjects with accelerated course of disease should be referred to secondary and tertiary centres. This requires increased awareness on the role and the frequency of bronchiectasis in primary care. Long-term continuous or cyclical use of antibiotics is recommended to stabilize or improve the course of evolving disease. Macrolides are a currently preferred option. Inhaled antibiotics are gaining importance and are the object of ongoing research interest. Practical challenges of inhaled antibiotic treatment remain the need of defining the best therapeutic regimen and optimizing true adherence.
[Mh] Termos MeSH primário: Antibacterianos/administração & dosagem
Bronquiectasia/tratamento farmacológico
Desenho de Drogas
[Mh] Termos MeSH secundário: Administração por Inalação
Obstrução das Vias Respiratórias/tratamento farmacológico
Obstrução das Vias Respiratórias/etiologia
Bronquiectasia/microbiologia
Bronquiectasia/patologia
Seres Humanos
Macrolídeos/administração & dosagem
Adesão à Medicação
Escarro
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); 0 (Macrolides)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180301
[Lr] Data última revisão:
180301
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171223
[St] Status:MEDLINE
[do] DOI:10.1080/17512433.2018.1421064


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[PMID]:29374126
[Au] Autor:Evans M
[Ad] Endereço:PO Box 21, Cranleigh, Surrey GU6 7YB, UK.
[Ti] Título:Continuing the campaign on brachycephalic dogs.
[So] Source:Vet Rec;182(4):114, 2018 01 27.
[Is] ISSN:2042-7670
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Craniossinostoses/veterinária
Doenças do Cão
[Mh] Termos MeSH secundário: Obstrução das Vias Respiratórias/veterinária
Animais
Cães
[Pt] Tipo de publicação:LETTER; COMMENT
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180223
[Lr] Data última revisão:
180223
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180128
[St] Status:MEDLINE
[do] DOI:10.1136/vr.k361


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[PMID]:29297639
[Au] Autor:Tikhonova IV; Kosyakova NI; Tankanag AV; Chemeris NK
[Ti] Título:Effects of the Airway Obstruction on the Skin Microcirculation in Patients with Bronchial Asthma.
[So] Source:Vestn Ross Akad Med Nauk;71(3):233-9, 2016.
[Is] ISSN:0869-6047
[Cp] País de publicação:Russia (Federation)
[La] Idioma:eng
[Ab] Resumo:Background: Pulmonary hemodynamic disorders depend on the inflammatory phases and severity of the obstructive syndrome. However, the effect of asthma bronchial obstruction on the state of peripheral hemodynamics remains insufficiently known. Aims: To study the effects of airway obstruction on skin blood flow parameters and its regulatory systems in patients with persistent atopic bronchial asthma in the remission state. Materials and Methods: A comparative study of the skin peripheral blood flow in patients with bronchial asthma with severe airway obstruction (1st group) and without obstruction (2nd group) was conducted. 20 patients with confirmed diagnosis of atopic asthma of 50­74 years old participated in the study. All patients received basic therapy in a constant dosing of high doses of inhaled glucocorticosteroids/long-acting beta-2-agonists. The control group included 20 healthy volunteers without evidence of bronchial obstruction. The study lasted for 3 months. The forced expiratory volume in 1 s (FEV1) was used to evaluate the bronchial obstruction by spirometry technique. Skin blood perfusion changes were recorded by laser Doppler flowmetry at rest and in response to short-term local ischemia. Registered peripheral blood flow signals were examined using the amplitude temporal filtering in five frequency intervals to identify the functional features of the peripheral blood flow regulation systems. Results: Consistent two-fold decrease of the oscillation amplitudes was found in the neurogenic interval at rest (p=0.031), as well as in the myogenic (p=0.043; p=0.031) and endothelial intervals (p=0.037; p≤0.001) both at rest and during the postocclusive reactive hyperemia respectively in the 1st group of patients with bronchial obstruction (FEV1 <80%) compared with the control group. No significant changes were revealed for skin blood flow parameters in the 2nd patient group (without obstruction, FEV1 >80%) in comparison to control subjects. Conclusions: The presence of bronchial obstruction has a significant impact on the changes of the amplitudes of skin blood flow oscillations in patients with bronchial asthma in the myogenic, neurogenic and endothelial intervals.
[Mh] Termos MeSH primário: Obstrução das Vias Respiratórias
Asma/fisiopatologia
Microcirculação
Pele
[Mh] Termos MeSH secundário: Idoso
Obstrução das Vias Respiratórias/diagnóstico
Obstrução das Vias Respiratórias/etiologia
Obstrução das Vias Respiratórias/fisiopatologia
Asma/complicações
Feminino
Seres Humanos
Hiperemia/diagnóstico
Fluxometria por Laser-Doppler/métodos
Masculino
Meia-Idade
Pele/irrigação sanguínea
Pele/fisiopatologia
Espirometria/métodos
Estatística como Assunto
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180220
[Lr] Data última revisão:
180220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180104
[St] Status:MEDLINE
[do] DOI:10.15690/vramn661


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Zhang, Linjie
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[PMID]:29265171
[Au] Autor:Zhang L; Mendoza-Sassi RA; Wainwright C; Klassen TP
[Ad] Endereço:Faculty of Medicine, Federal University of Rio Grande, Rua Visconde Paranaguá 102, Centro, Rio Grande, RS, Brazil, 96201-900.
[Ti] Título:Nebulised hypertonic saline solution for acute bronchiolitis in infants.
[So] Source:Cochrane Database Syst Rev;12:CD006458, 2017 12 21.
[Is] ISSN:1469-493X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Airway oedema (swelling) and mucus plugging are the principal pathological features in infants with acute viral bronchiolitis. Nebulised hypertonic saline solution (≥ 3%) may reduce these pathological changes and decrease airway obstruction. This is an update of a review first published in 2008, and previously updated in 2010 and 2013. OBJECTIVES: To assess the effects of nebulised hypertonic (≥ 3%) saline solution in infants with acute bronchiolitis. SEARCH METHODS: We searched the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, MEDLINE Epub Ahead of Print, In-Process & Other Non-Indexed Citations, Ovid MEDLINE Daily, Embase, CINAHL, LILACS, and Web of Science on 11 August 2017. We also searched the World Health Organization International Clinical Trials Registry Platform (WHO ICTRP) and ClinicalTrials.gov on 8 April 2017. SELECTION CRITERIA: We included randomised controlled trials and quasi-randomised controlled trials using nebulised hypertonic saline alone or in conjunction with bronchodilators as an active intervention and nebulised 0.9% saline, or standard treatment as a comparator in children under 24 months with acute bronchiolitis. The primary outcome for inpatient trials was length of hospital stay, and the primary outcome for outpatients or emergency department trials was rate of hospitalisation. DATA COLLECTION AND ANALYSIS: Two review authors independently performed study selection, data extraction, and assessment of risk of bias in included studies. We conducted random-effects model meta-analyses using Review Manager 5. We used mean difference (MD), risk ratio (RR), and their 95% confidence intervals (CI) as effect size metrics. MAIN RESULTS: We identified 26 new trials in this update, of which 9 await classification due to insufficient data for eligibility assessment, and 17 trials (N = 3105) met the inclusion criteria. We included a total of 28 trials involving 4195 infants with acute bronchiolitis, of whom 2222 infants received hypertonic saline.Hospitalised infants treated with nebulised hypertonic saline had a statistically significant shorter mean length of hospital stay compared to those treated with nebulised 0.9% saline (MD -0.41 days, 95% CI -0.75 to -0.07; P = 0.02, I² = 79%; 17 trials; 1867 infants) (GRADE quality of evidence: low). Infants who received hypertonic saline also had statistically significant lower post-inhalation clinical scores than infants who received 0.9% saline in the first three days of treatment (day 1: MD -0.77, 95% CI -1.18 to -0.36, P < 0.001; day 2: MD -1.28, 95% CI -1.91 to -0.65, P < 0.001; day 3: MD -1.43, 95% CI -1.82 to -1.04, P < 0.001) (GRADE quality of evidence: low).Nebulised hypertonic saline reduced the risk of hospitalisation by 14% compared with nebulised 0.9% saline among infants who were outpatients and those treated in the emergency department (RR 0.86, 95% CI 0.76 to 0.98; P = 0.02, I² = 7%; 8 trials; 1723 infants) (GRADE quality of evidence: moderate).Twenty-four trials presented safety data: 13 trials (1363 infants, 703 treated with hypertonic saline) did not report any adverse events, and 11 trials (2360 infants, 1265 treated with hypertonic saline) reported at least one adverse event, most of which were mild and resolved spontaneously. AUTHORS' CONCLUSIONS: Nebulised hypertonic saline may modestly reduce length of stay among infants hospitalised with acute bronchiolitis and improve clinical severity score. Treatment with nebulised hypertonic saline may also reduce the risk of hospitalisation among outpatients and emergency department patients. However, we assessed the quality of the evidence as low to moderate.
[Mh] Termos MeSH primário: Bronquiolite Viral/terapia
Solução Salina Hipertônica/administração & dosagem
[Mh] Termos MeSH secundário: Doença Aguda
Obstrução das Vias Respiratórias
Broncodilatadores/administração & dosagem
Seres Humanos
Lactente
Tempo de Internação
Nebulizadores e Vaporizadores
Readmissão do Paciente/estatística & dados numéricos
Ensaios Clínicos Controlados Aleatórios como Assunto
Índice de Gravidade de Doença
[Pt] Tipo de publicação:JOURNAL ARTICLE; META-ANALYSIS; RESEARCH SUPPORT, NON-U.S. GOV'T; REVIEW
[Nm] Nome de substância:
0 (Bronchodilator Agents); 0 (Saline Solution, Hypertonic)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180123
[Lr] Data última revisão:
180123
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171222
[St] Status:MEDLINE
[do] DOI:10.1002/14651858.CD006458.pub4


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[PMID]:29157546
[Au] Autor:Steffy DD; Tang CS
[Ad] Endereço:United States Navy, James A. Lovell Federal Health Care Center, 3001 Green Bay Road, North Chicago, IL 60064, USA. Electronic address: Dr.Steffy@beamreaders.com.
[Ti] Título:Radiographic Evaluation of Sleep-Disordered Breathing.
[So] Source:Radiol Clin North Am;56(1):177-185, 2018 Jan.
[Is] ISSN:1557-8275
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Sleep-disordered breathing and obstructive sleep apnea are becoming more prevalent in today's population. Management of these conditions can be difficult and this diagnosis is often overlooked by clinicians. An increased awareness and understanding of craniofacial structures and anatomic relationships can aid the clinician in identifying at-risk patients, and improve treatment outcomes. An airway review of 3-dimensional computed tomography imaging can identify (1) anatomic variations that contribute to obstructive airway complications, and (2) measurable dimensions to identify at risk patients. This article provides instruction on the key anatomic landmarks and imaging protocols for radiographic airway evaluation.
[Mh] Termos MeSH primário: Obstrução das Vias Respiratórias/diagnóstico por imagem
Obstrução das Vias Respiratórias/patologia
Cavidade Nasal/diagnóstico por imagem
Faringe/diagnóstico por imagem
Síndromes da Apneia do Sono/diagnóstico por imagem
Síndromes da Apneia do Sono/patologia
[Mh] Termos MeSH secundário: Obstrução das Vias Respiratórias/complicações
Tomografia Computadorizada de Feixe Cônico/métodos
Diagnóstico Diferencial
Seres Humanos
Cavidade Nasal/patologia
Faringe/patologia
Síndromes da Apneia do Sono/etiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171128
[Lr] Data última revisão:
171128
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171122
[St] Status:MEDLINE


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[PMID]:29132582
[Au] Autor:Kovacs G; Sowers N
[Ad] Endereço:Department of Emergency Medicine, Division of Medical Education, Dalhousie University, 3rd Floor, HI Site, Suite 355, Room 364D, Halifax, Nova Scotia B3H 3A7, Canada; Department of Anaesthesia, Division of Medical Education, Dalhousie University, 3rd Floor, HI Site, Suite 355, Room 364D, Halifax, Nova Scotia B3H 3A7, Canada; Department of Medical Neurosciences, Division of Medical Education, Dalhousie University, 3rd Floor, HI Site, Suite 355, Room 364D, Halifax, Nova Scotia B3H 3A7, Canada; Charles V. Keating Trauma & Emergency Centre, QEII Health Sciences Centre, 1799 Robie Street, Halifax, Nova Scotia B3H 3G1, Canada. Electronic address: gkovacs@dal.ca.
[Ti] Título:Airway Management in Trauma.
[So] Source:Emerg Med Clin North Am;36(1):61-84, 2018 Feb.
[Is] ISSN:1558-0539
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Airway management in the trauma patient presents numerous unique challenges beyond placement of an endotracheal tube and outcomes are dependent on the provider's ability to anticipate difficulty. Airway management strategies for the care of the polytrauma patient are reviewed, with specific considerations for those presenting with traumatic brain injury, suspected c-spine injury, the contaminated airway, the agitated trauma patient, maxillofacial trauma, and the traumatized airway. An approach to airway management that considers the potential anatomic and physiologic challenges in caring for these complicated trauma patients is presented.
[Mh] Termos MeSH primário: Manuseio das Vias Aéreas
Ferimentos e Lesões/terapia
[Mh] Termos MeSH secundário: Manuseio das Vias Aéreas/métodos
Obstrução das Vias Respiratórias/etiologia
Obstrução das Vias Respiratórias/terapia
Traumatismos Craniocerebrais/complicações
Traumatismos Craniocerebrais/terapia
Seres Humanos
Intubação Intratraqueal
Ferimentos e Lesões/complicações
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171128
[Lr] Data última revisão:
171128
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171115
[St] Status:MEDLINE


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[PMID]:29132580
[Au] Autor:Mikrogianakis A; Grant V
[Ad] Endereço:Department of Pediatrics, Alberta Children's Hospital, University of Calgary, 2888 Shaganappi Trail Northwest, Calgary, Alberta T3B 6A8, Canada; Department of Emergency Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada. Electronic address: angelo.mikrogianakis@albertahealthservices.ca.
[Ti] Título:The Kids Are Alright: Pediatric Trauma Pearls.
[So] Source:Emerg Med Clin North Am;36(1):237-257, 2018 Feb.
[Is] ISSN:1558-0539
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Pediatric patients with trauma pose unique challenges, both practical and cognitive, to front-line care providers. The combination of anatomic, physiologic, and metabolic factors leads to unique injury patterns with different approaches and responses to treatment compared with adults. A similar traumatic mechanism can lead to slightly different internal injuries with unique management and treatment strategies between the two groups. This article is intended for community, nonpediatric trauma centers, and emergency physicians who are frequently required to assess, resuscitate, and stabilize injured children before they can be safely transferred to a pediatric trauma center for ongoing definitive care and rehabilitation.
[Mh] Termos MeSH primário: Ferimentos e Lesões/terapia
[Mh] Termos MeSH secundário: Traumatismos Abdominais/diagnóstico
Traumatismos Abdominais/terapia
Fatores Etários
Manuseio das Vias Aéreas
Obstrução das Vias Respiratórias/diagnóstico
Obstrução das Vias Respiratórias/terapia
Criança
Traumatismos Craniocerebrais/diagnóstico
Traumatismos Craniocerebrais/terapia
Seres Humanos
Ressuscitação
Traumatismos da Medula Espinal/diagnóstico
Traumatismos da Medula Espinal/terapia
Traumatismos Torácicos/diagnóstico
Traumatismos Torácicos/terapia
Ferimentos e Lesões/diagnóstico
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171128
[Lr] Data última revisão:
171128
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171115
[St] Status:MEDLINE


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[PMID]:29054229
[Au] Autor:Kayawake H; Chen-Yoshikawa TF; Oda H; Motoyama H; Hamaji M; Menju T; Aoyama A; Sato T; Sonobe M; Date H
[Ad] Endereço:Department of Thoracic Surgery, Kyoto University, Kyoto, Japan.
[Ti] Título:Complications of Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration.
[So] Source:Ann Thorac Surg;104(5):e363-e365, 2017 Nov.
[Is] ISSN:1552-6259
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is considered useful for the staging and diagnosis of lung cancer or thoracic lymph node enlargement; however, little is known about its complications. Between July 2009 and November 2016, 413 patients underwent EBUS-TBNA, and four complications (0.97%) occurred. Here we report four cases involving complications of EBUS-TBNA, including mediastinitis (n = 2), obstructive pneumonia (n = 1), and airway obstruction requiring admission to the intensive care unit (n = 1). All patients recovered with appropriate medical treatment. Despite their low incidence, the complications associated with EBUS-TBNA can be serious.
[Mh] Termos MeSH primário: Aspiração por Agulha Fina Guiada por Ultrassom Endoscópico/efeitos adversos
Neoplasias Pulmonares/patologia
Linfonodos/patologia
Mediastinite/etiologia
[Mh] Termos MeSH secundário: Idoso
Obstrução das Vias Respiratórias/diagnóstico por imagem
Obstrução das Vias Respiratórias/etiologia
Obstrução das Vias Respiratórias/terapia
Estudos de Coortes
Aspiração por Agulha Fina Guiada por Ultrassom Endoscópico/métodos
Endossonografia/efeitos adversos
Endossonografia/métodos
Feminino
Seres Humanos
Neoplasias Pulmonares/cirurgia
Linfonodos/cirurgia
Masculino
Mediastinite/diagnóstico por imagem
Mediastinite/terapia
Meia-Idade
Invasividade Neoplásica/patologia
Estadiamento de Neoplasias
Pneumonia Bacteriana/etiologia
Pneumonia Bacteriana/microbiologia
Pneumonia Bacteriana/terapia
Prognóstico
Radiografia Torácica/métodos
Estudos Retrospectivos
Medição de Risco
Tomografia Computadorizada por Raios X/métodos
Resultado do Tratamento
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171102
[Lr] Data última revisão:
171102
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171022
[St] Status:MEDLINE


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[PMID]:28964308
[Au] Autor:Çetin M; Bozan N
[Ad] Endereço:Department of Pediatric Cardiology, Yuzuncu Yil University, Van, Turkey. Electronic address: drmecnun@hotmail.com.
[Ti] Título:The effects of adenotonsillar hypertrophy corrective surgery on left ventricular functions and pulmonary artery pressure in children.
[So] Source:Int J Pediatr Otorhinolaryngol;101:41-46, 2017 Oct.
[Is] ISSN:1872-8464
[Cp] País de publicação:Ireland
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: Comparison of left ventricular functions in preoperative and postoperative periods of children with adenotonsillar hypertrophy (ATH) who have findings of upper airway obstruction (UAO), using echocardiographic parameters. METHODS: Thirty children who were diagnosed with UAO due to ATH, and who have undergone adenoidectomy/adenotonsillectomy and 30 healthy children, between 2 and 11 years of age, were included in the study. Patient group was evaluated by the pulsed wave tissue Doppler echocardiography, as well as with conventional echocardiography, before and 6 months after the operation. RESULTS: Of 30 children in study group, 18 (60%) had adenotonsillectomy and 12 (40%) had adenoidectomy. The differences between groups regarding myocardial performance index (MPI) was not statistically significant (p = 0.847). There was not any statistically significant difference between groups in terms of mitral isovolemic acceleration (MIVA) (2.28 ± 0.67, 2.24 ± 0.55, 2.23 ± 0.49; p = 0.943, respectively). Interventricular septum diameter (IVSD) was significantly higher in preoperative group than postoperative and control groups (3.68 ± 0.52, 3.50 ± 0.40, 3.38 ± 0.60; p = 0.028, respectively). Pulmonary acceleration time (PAcT) was found to be significantly lower in preoperative group compared to postoperative and control groups (107.64 ± 16.60, 119.52 ± 15.95, 120.47 ± 16.19; p = 0.004, respectively). Mean pulmonary arterial pressure (mPAP) was significantly higher in preoperative group than postoperative and control groups (30.58 ± 8.11, 25.23 ± 9.07, 25.00 ± 6.52; p = 0.002, respectively). In postoperative group mPAP was found to be similar to the control group. CONCLUSIONS: Clinical or subclinical left ventricle (LV) dysfunction in children with ATH who have findings of UAO was not determined while mean pulmonary arterial pressure was significantly higher compared with the control cases. Besides early adenotonsillectomy is a beneficial treatment option for these patients.
[Mh] Termos MeSH primário: Adenoidectomia/efeitos adversos
Tonsila Faríngea/cirurgia
Obstrução das Vias Respiratórias/cirurgia
Tonsila Palatina/cirurgia
Artéria Pulmonar/fisiopatologia
Tonsilectomia/efeitos adversos
Função Ventricular Esquerda/fisiologia
[Mh] Termos MeSH secundário: Obstrução das Vias Respiratórias/etiologia
Criança
Pré-Escolar
Ecocardiografia
Feminino
Seres Humanos
Hipertrofia/cirurgia
Masculino
Período Pós-Operatório
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171023
[Lr] Data última revisão:
171023
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171002
[St] Status:MEDLINE



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