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[PMID]:29313370
[Au] Autor:Alvi SA; Jones JW; Lin J
[Ad] Endereço:1 Department of Otolaryngology - Head & Neck Surgery, University of Kansas Medical Center, Kansas City, Kansas, USA.
[Ti] Título:Bilateral Ossicular Head Dehiscence Into the Middle Cranial Fossa.
[So] Source:Ann Otol Rhinol Laryngol;127(3):209-212, 2018 Mar.
[Is] ISSN:1943-572X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: To describe a unique case of bilateral dehiscence of the malleus and incus heads into the middle fossa making contact with the temporal lobes, along with its clinical implications. METHODS: An analysis of a patient case and review of pertinent literature were performed. RESULTS: A patient with a history of right-sided mastoidectomy for cholesteatoma was evaluated for persistent conductive hearing loss. On computed tomography (CT) and magnetic resonance imaging (MRI), the patient had a complete dehiscence of the tegmen tympani on the right, with ossicular heads being located above the floor of the middle cranial fossa. A similar finding to a milder degree was noted on the left. The patient underwent revision tympanoplasty with mastoidectomy with removal of the incus and ossicular chain reconstruction and middle fossa craniotomy for repair of the right epitympanic dehiscence. CONCLUSIONS: We present some of the unique imaging and operative findings involved in an unusual presentation of encephalocele in which the bilateral malleus and incus heads rise above the level of the middle fossa floor.
[Mh] Termos MeSH primário: Colesteatoma/cirurgia
Fossa Craniana Média
Encefalocele
Perda Auditiva Condutiva
Mastoidectomia/efeitos adversos
Reoperação/métodos
Timpanoplastia/métodos
[Mh] Termos MeSH secundário: Adulto
Fossa Craniana Média/diagnóstico por imagem
Fossa Craniana Média/patologia
Encefalocele/diagnóstico
Encefalocele/etiologia
Perda Auditiva Condutiva/diagnóstico
Perda Auditiva Condutiva/etiologia
Seres Humanos
Imagem por Ressonância Magnética/métodos
Masculino
Mastoidectomia/métodos
Complicações Pós-Operatórias/diagnóstico
Tomografia Computadorizada por Raios X/métodos
Resultado do Tratamento
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180221
[Lr] Data última revisão:
180221
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180110
[St] Status:MEDLINE
[do] DOI:10.1177/0003489417751956


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[PMID]:29298506
[Au] Autor:Malafronte G
[Ad] Endereço:1 S.G. Moscati Hospital Company of National Importance, Avellino, Italy.
[Ti] Título:A New Reversal Steps Stapedotomy.
[So] Source:Ann Otol Rhinol Laryngol;127(3):167-170, 2018 Mar.
[Is] ISSN:1943-572X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To evaluate whether removal of the stapes head and not the entire stapes superstructure prevents footplate complications. STUDY DESIGN: Prospective study. PATIENTS: One hundred and forty-five patients with otosclerosis were included. Patients were divided into 2 groups as follows: Individuals in group 1 (n = 75) underwent removal of the entire stapes superstructure; individuals in group 2 (n = 70) underwent removal of the stapes head only. These 2 groups were further subdivided into 2 subgroups based on the type of otosclerosis. Group 1a included 55 cases of marginal otosclerosis, while group 1b included 15 diffusive and 5 biscuit otosclerosis cases. Group 2a included 51 marginal otosclerosis cases, while group 2b included 14 diffuse and 5 biscuit otosclerosis cases. Estimations were made regarding statistical correlation between type of reversal steps stapedotomy, otosclerosis type, incidence of footplate complications, and hearing results. RESULTS: There were 9 footplate complications in group 1b and no complications in group 2b. This difference was significant. Air-bone gap closure to within 10 dB was achieved in 65% of cases in group 1b and 94.7% in group 2b. This difference was significant. CONCLUSION: The new stapedotomy prevented footplate complications and improved hearing results in diffuse and biscuit otosclerosis.
[Mh] Termos MeSH primário: Otosclerose
Complicações Pós-Operatórias
Cirurgia do Estribo
Estribo/patologia
[Mh] Termos MeSH secundário: Adulto
Idoso
Feminino
Perda Auditiva Condutiva/diagnóstico
Perda Auditiva Condutiva/etiologia
Perda Auditiva Condutiva/cirurgia
Testes Auditivos/métodos
Seres Humanos
Itália
Masculino
Meia-Idade
Otosclerose/diagnóstico
Otosclerose/cirurgia
Avaliação de Processos e Resultados (Cuidados de Saúde)
Complicações Pós-Operatórias/diagnóstico
Complicações Pós-Operatórias/prevenção & controle
Cirurgia do Estribo/efeitos adversos
Cirurgia do Estribo/métodos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180221
[Lr] Data última revisão:
180221
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180105
[St] Status:MEDLINE
[do] DOI:10.1177/0003489417751156


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[PMID]:29267386
[Au] Autor:Sarmento KMA; Sampaio ALL; Santos TGT; Oliveira CACP
[Ad] Endereço:Department of Otolaryngology, Brasilia Military Police Hospital, Brasilia, DF, Brazil.
[Ti] Título:High-frequency conductive hearing loss as a diagnostic test for incomplete ossicular discontinuity in non-cholesteatomatous chronic suppurative otitis media.
[So] Source:PLoS One;12(12):e0189997, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Chronic suppurative otitis media, with or without cholesteatoma, may lead to erosion of the ossicles and discontinuity of the ossicular chain. In incomplete ossicular discontinuity (IOD), partial erosion of the ossicles occurs, but some sound transmission is noted throughout the ossicular chain. High-frequency conductive hearing loss (HfCHL) has been considered a hallmark of incomplete ossicular discontinuity. This study aims to evaluate the use of HfCHL as a preoperative predictor of IOD in patients with non-cholesteatomatous chronic suppurative otitis media. The HfCHL test was defined as the preoperative air-bone gap (ABG) at 4 kHz minus the average of the ABG at 0.25 and 0.5 kHz. The test was applied in 328 patients before surgery and compared to intraoperative findings as the gold standard. At surgery, 201 (61.3%) patients had an intact ossicular chain, 44 (13.4%) had a complete ossicular discontinuity, and 83 (25.3%) exhibited an IOD. The best cutoff level was calculated as 10 dB. The HfCHL test to diagnose IOD had a sensitivity of 83% and a specificity of 92% with a post-test probability of 78% and a likelihood ratio of 10.2. We concluded that the HfCHL test is highly effective in predicting IOD in patients with non-cholesteatomatous chronic suppurative otitis media and that it should be used routinely as a screening test prior to surgery.
[Mh] Termos MeSH primário: Ossículos da Orelha/patologia
Perda Auditiva Condutiva/complicações
Otite Média Supurativa/complicações
[Mh] Termos MeSH secundário: Adolescente
Adulto
Audiometria de Tons Puros
Ossículos da Orelha/fisiopatologia
Feminino
Seres Humanos
Masculino
Meia-Idade
Otite Média Supurativa/patologia
Estudos Prospectivos
Sensibilidade e Especificidade
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180116
[Lr] Data última revisão:
180116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171222
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0189997


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[PMID]:29224748
[Au] Autor:Bianchi PM; Bianchi A; Digilio MC; Tucci FM; Sitzia E; De Vincentiis GC
[Ad] Endereço:Surgery Department, Otorhinolaryngology Unit, Bambino Gesù Paediatric Hospital, Scientific Research Institute, 00100 Rome, Italy. Electronic address: piermarco.bianchi@opbg.net.
[Ti] Título:Audiological findings in a de novo mutation of ANKRD11 gene in KBG syndrome: Report of a case and review of the literature.
[So] Source:Int J Pediatr Otorhinolaryngol;103:109-112, 2017 Dec.
[Is] ISSN:1872-8464
[Cp] País de publicação:Ireland
[La] Idioma:eng
[Ab] Resumo:KBG syndrome is a rare genetic disorder, due to a mutation of ANKRD11, characterized by specific craniofacial dysmorphism, short stature and macrodontia of upper central incisors, intellectual disability and skeletal anomalies. We report a de novo mutation of ANKRD11 gene in a 7-years old girl, affected by KBG syndrome with bilateral conductive hearing loss. The aim of this article was to review the audiological findings of this syndrome.
[Mh] Termos MeSH primário: Anormalidades Múltiplas/diagnóstico
Doenças do Desenvolvimento Ósseo/diagnóstico
Perda Auditiva Condutiva/etiologia
Deficiência Intelectual/diagnóstico
Proteínas Repressoras/genética
Anormalidades Dentárias/diagnóstico
[Mh] Termos MeSH secundário: Anormalidades Múltiplas/genética
Audiometria
Doenças do Desenvolvimento Ósseo/complicações
Doenças do Desenvolvimento Ósseo/genética
Criança
Facies
Feminino
Seres Humanos
Deficiência Intelectual/complicações
Deficiência Intelectual/genética
Mutação
Fenótipo
Anormalidades Dentárias/complicações
Anormalidades Dentárias/genética
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (ANKRD11 protein, human); 0 (Repressor Proteins)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180104
[Lr] Data última revisão:
180104
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171212
[St] Status:MEDLINE


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[PMID]:29224768
[Au] Autor:Schwarz Y; Kaufman GN; Daniel SJ
[Ad] Endereço:Department of Otolaryngology-Head and Neck Surgery, The Montreal Children's Hospital, McGill University, Montreal, QC, Canada.
[Ti] Título:Newborn hearing screening failure and maternal factors during pregnancy.
[So] Source:Int J Pediatr Otorhinolaryngol;103:65-70, 2017 Dec.
[Is] ISSN:1872-8464
[Cp] País de publicação:Ireland
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: Temporary conductive hearing loss due to amniotic fluid accumulation in the middle ear cavity may lead to failure (false positive) in newborn hearing screening tests. The aim of this study was to identify whether amniotic fluid index has association with failure of the initial newborn otoacoustic emission (OAE) screening test. METHODS: A cohort study in a tertiary hospital center (Royal Victoria Hospital, Montréal) was constructed from 70 newborns that failed the OAE test, but passed a subsequent auditory brainstem response (ABR) test, and 75 randomly selected newborns that passed initial otoacoustic emission testing. Maternal (including the amniotic fluid index in the third trimester) and newborn clinical data were extracted from medical records. Statistical association models were built to determine variables that influenced hearing screen passage or failure. RESULTS: The two arms of the cohort had no significant differences in maternal or child clinical indices, including in amniotic fluid index. Calculated as individual odds ratios, maternal tobacco [95% CI of odds ratio: 0.04, 0.59, p = 0.0078], and drug use [95% CI of odds ratio: 0.0065, 0.72, p = 0.058] [borderline significance] were associated with failing the otoacoustic emission testing. CONCLUSIONS: Amniotic fluid index was not found to be associated with failure of otoacoustic emission screening in newborns. However, our study unveiled an interesting unexpected association of OAE failure with maternal smoking and/or drug use. This finding can help alleviate some of the time, cost and parental anxiety related to failed OAE screening. In selected cases of maternal smoking or drug use we might want to replace or add OAE to the ABR test in newborn hearing screening protocols, that don't perform both tests before discharge.
[Mh] Termos MeSH primário: Líquido Amniótico
Perda Auditiva Condutiva/diagnóstico
Testes Auditivos/métodos
Triagem Neonatal/métodos
[Mh] Termos MeSH secundário: Canadá
Estudos de Coortes
Potenciais Evocados Auditivos do Tronco Encefálico
Feminino
Perda Auditiva Condutiva/etiologia
Seres Humanos
Recém-Nascido
Masculino
Emissões Otoacústicas Espontâneas/fisiologia
Gravidez
Fatores de Risco
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171226
[Lr] Data última revisão:
171226
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171212
[St] Status:MEDLINE


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[PMID]:29073906
[Au] Autor:Yang A; Kim J; Ki CS; Hong SH; Cho SY; Jin DK
[Ad] Endereço:Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Korea.
[Ti] Título:HDR syndrome with a novel mutation in GATA3 mimicking a congenital X-linked stapes gusher: a case report.
[So] Source:BMC Med Genet;18(1):121, 2017 Oct 26.
[Is] ISSN:1471-2350
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Hypoparathyroidism, sensorineural hearing loss, and renal disease (HDR) syndrome, also known as Barakat syndrome, is a rare genetic disorder with high phenotypic heterogeneity caused by haploinsufficiency of the GATA3 gene on chromosome 10p14-p15. For these reasons, the diagnosis of HDR syndrome is challenging and requires a high index of suspicion as well as genetic analysis. CASE PRESENTATION: A 14-month-old boy, with sensorineural hearing loss in both ears, showed typical radiological features of X-linked stapes gusher on preoperative temporal bone computed tomography (CT) for cochlear implantations. Then after his discharge from hospital, he suffered a hypocalcemic seizure and we discovered a renal cyst during investigation of hypocalcemia. He was finally diagnosed with HDR syndrome by clinical findings, which were confirmed by molecular genetic testing. Direct sequencing of the GATA3 gene showed a heterozygous 2-bp deletion (c.1201_1202delAT), which is predicted to cause a frameshift of the reading frame (p.Met401Valfs*106). CONCLUSIONS: To our knowledge, this is the first case of HDR syndrome with a novel de novo variant mimicking a congenital X-linked stapes gusher syndrome. Novel mutations and the diversity of clinical manifestations expand the genotypic and phenotypic spectrum of HDR syndrome. Diagnosis of HDR syndrome is still challenging, but clinicians should consider it in their differential diagnosis for children with a wide range of clinical manifestations including hypocalcemia induced seizures and deafness. We hope that this case will contribute to further understanding and studies of HDR-associated GATA3 mutations.
[Mh] Termos MeSH primário: Cromossomos Humanos Par 10/química
Implante Coclear
Mutação da Fase de Leitura
Fator de Transcrição GATA3/genética
Perda Auditiva Neurossensorial/diagnóstico
Hipoparatireoidismo/diagnóstico
Nefrose/diagnóstico
[Mh] Termos MeSH secundário: Diagnóstico Diferencial
Expressão Gênica
Doenças Genéticas Ligadas ao Cromossomo X/diagnóstico
Doenças Genéticas Ligadas ao Cromossomo X/genética
Doenças Genéticas Ligadas ao Cromossomo X/fisiopatologia
Haploinsuficiência
Perda Auditiva Condutiva/diagnóstico
Perda Auditiva Condutiva/genética
Perda Auditiva Condutiva/fisiopatologia
Perda Auditiva Neurossensorial/genética
Perda Auditiva Neurossensorial/fisiopatologia
Perda Auditiva Neurossensorial/cirurgia
Heterozigoto
Seres Humanos
Hipoparatireoidismo/genética
Hipoparatireoidismo/fisiopatologia
Hipoparatireoidismo/cirurgia
Lactente
Masculino
Nefrose/genética
Nefrose/fisiopatologia
Nefrose/cirurgia
Tomografia Computadorizada por Raios X
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (GATA3 Transcription Factor); 0 (GATA3 protein, human)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171102
[Lr] Data última revisão:
171102
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171028
[St] Status:MEDLINE
[do] DOI:10.1186/s12881-017-0484-6


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[PMID]:29053746
[Au] Autor:Trinkaus E; Villotte S
[Ad] Endereço:Department of Anthropology, Washington University, Saint Louis, Missouri, United States of America.
[Ti] Título:External auditory exostoses and hearing loss in the Shanidar 1 Neandertal.
[So] Source:PLoS One;12(10):e0186684, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The Late Pleistocene Shanidar 1 older adult male Neandertal is known for the crushing fracture of his left orbit with a probable reduction in vision, the loss of his right forearm and hand, and evidence of an abnormal gait, as well as probable diffuse idiopathic skeletal hyperostosis. He also exhibits advanced external auditory exostoses in his left auditory meatus and larger ones with complete bridging across the porus in the right meatus (both Grade 3). These growths indicate at least unilateral conductive hearing (CHL) loss, a serious sensory deprivation for a Pleistocene hunter-gatherer. This condition joins the meatal atresia of the Middle Pleistocene Atapuerca-SH Cr.4 in providing evidence of survival with conductive hearing loss (and hence serious sensory deprivation) among these Pleistocene humans. The presence of CHL in these fossils thereby reinforces the paleobiological and archeological evidence for supporting social matrices among these Pleistocene foraging peoples.
[Mh] Termos MeSH primário: Orelha Externa
Exostose
Fósseis
Perda Auditiva Condutiva
Hominidae
Homem de Neandertal
[Mh] Termos MeSH secundário: Animais
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171113
[Lr] Data última revisão:
171113
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171021
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0186684


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[PMID]:28964294
[Au] Autor:Bezdjian A; Bruijnzeel H; Daniel SJ; Grolman W; Thomeer HGXM
[Ad] Endereço:Department of Experimental Surgery, McGill University, Montreal, Quebec, Canada; McGill Auditory Sciences Lab, McGill University Health Centre Research Institute, Montreal, Quebec, Canada; Department of Otorhinolaryngology - Head and Neck Surgery, University Medical Centre Utrecht, Utrecht, The Neth
[Ti] Título:Preliminary audiologic and peri-operative outcomes of the Sophono™ transcutaneous bone conduction device: A systematic review.
[So] Source:Int J Pediatr Otorhinolaryngol;101:196-203, 2017 Oct.
[Is] ISSN:1872-8464
[Cp] País de publicação:Ireland
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To delineate the auditory functional improvement and peri-operative outcomes of the Sophono™ transcutaneous bone conduction device. METHODS: Eligible articles presenting patients implanted with the Sophono™ were identified through a comprehensive search of PubMed and Embase electronic databases. All relevant articles were reviewed to justify inclusion independently by 2 authors. Studies that successfully passed critical appraisal for directness of evidence and risk of bias were included. RESULTS: From a total of 125 articles, 8 studies encompassing 86 patients using 99 implants were selected. Most patients (79.1%) were children. Ear atresia (67.5%) was the most frequently reported indication for Sophono™ implantation. Overall pure tone average auditory improvement was 31.10 (±8.29) decibel. During a mean follow-up time of 12.48 months, 25 patients (29%) presented with post-operative complications from which 3 were deemed as serious implant-related adverse events (3.5%). CONCLUSIONS: The Sophono™ transcutaneous bone conduction device shows promising functional improvement, no intra-operative complications and minor post-operative skin related complications. If suitable, the device could be a proposed solution for the rehabilitation of hearing in children meeting eligibility criteria. A wearing schedule must be implemented in order to reduce magnet-related skin complications.
[Mh] Termos MeSH primário: Condução Óssea/fisiologia
Auxiliares de Audição
Perda Auditiva Condutiva/cirurgia
[Mh] Termos MeSH secundário: Audiologia
Criança
Feminino
Audição
Seres Humanos
Masculino
Complicações Pós-Operatórias
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171016
[Lr] Data última revisão:
171016
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171002
[St] Status:MEDLINE


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[PMID]:28964287
[Au] Autor:Fan X; Wang Y; Wang P; Fan Y; Chen Y; Zhu Y; Chen X
[Ad] Endereço:Department of Otolaryngology, Peking Union Medical College Hospital, Beijing, PR China. Electronic address: 15600747630@163.com.
[Ti] Título:Aesthetic and hearing rehabilitation in patients with bilateral microtia-atresia.
[So] Source:Int J Pediatr Otorhinolaryngol;101:150-157, 2017 Oct.
[Is] ISSN:1872-8464
[Cp] País de publicação:Ireland
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: To evaluate the safety and efficacy of auricle reconstruction and active transcutaneous bone-conduction implantation in patients with bilateral microtia-atresia. DESIGN: Patients were chosen prospectively, with each being his/her own control. SETTING: The setting was a tertiary referral center. PARTICIPANTS: Twelve patients, aged 6-18 years, with bilateral microtia-atresia suffering from bilateral conductive hearing loss. All had an upper bone conduction threshold limit of 45 dB HL at frequencies of 0.5-4 kHz. MAIN OUTCOME MEASURES: Patient satisfaction with the reconstructed auricle was rated as highly satisfactory, basically satisfactory, or unsatisfactory. Mean pure-tone thresholds and speech audiometry test results were compared among patients unaided, with a soft-band Bonebridge, and with an implanted Bonebridge. Subjective satisfaction was analyzed using three questionnaires: the Abbreviated Profile of Hearing Aid Benefit (APHAB), the Glasgow children's benefit inventory (GCBI), and the International Outcome Inventory for Hearing Aids (IOI-HA). RESULTS: All patients who underwent auricle reconstruction expressed satisfaction with their appearance. The mean pure-tone thresholds of unaided patients and those with soft-band and implanted Bonebridge were 55.25 ± 3.43 dBHL, 31.37 ± 3.03 dBHL, and 21.25 ± 2.16 dBHL, respectively. The mean speech discrimination scores measured in a sound field with a presentation level of 65 dB SPL under these three conditions were 46.0 ± 0.11%, 80.0 ± 0.09%, and 94.0 ± 0.02%, respectively. Questionnaires demonstrated patients' benefits and satisfaction with this surgery. CONCLUSIONS: The surgical procedure involving auricle reconstruction and Bonebridge implantation was safe and effective for patients with bilateral microtia-atresia, solving both appearance and hearing problems.
[Mh] Termos MeSH primário: Microtia Congênita/cirurgia
Orelha Externa/cirurgia
Auxiliares de Audição/efeitos adversos
Perda Auditiva Condutiva/cirurgia
Procedimentos Cirúrgicos Reconstrutivos/métodos
[Mh] Termos MeSH secundário: Adolescente
Audiometria da Fala
Criança
Feminino
Audição
Testes Auditivos
Seres Humanos
Masculino
Satisfação do Paciente/estatística & dados numéricos
Estudos Prospectivos
Procedimentos Cirúrgicos Reconstrutivos/efeitos adversos
Inquéritos e Questionários
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171023
[Lr] Data última revisão:
171023
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171002
[St] Status:MEDLINE


  10 / 3286 MEDLINE  
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[PMID]:28688567
[Au] Autor:Govil N; Kaffenberger TM; Shaffer AD; Chi DH
[Ad] Endereço:Department of Otolaryngology, University of Pittsburgh Medical Center, Eye and Ear Institute, Suite 519, 203 Lothrop St, Pittsburgh, PA 15213, USA.
[Ti] Título:Factors influencing hearing outcomes in pediatric patients undergoing ossicular chain reconstruction.
[So] Source:Int J Pediatr Otorhinolaryngol;99:60-65, 2017 Aug.
[Is] ISSN:1872-8464
[Cp] País de publicação:Ireland
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: Ossicular chain disruption in children leads to conductive hearing loss. Few studies have focused on factors influencing successful results in pediatric ossicular chain reconstruction (OCR). We aim to determine whether demographic or surgical factors affect hearing outcomes in pediatric OCR. METHODS: We conducted a retrospective chart review of 120 patients undergoing OCR at our institution, a tertiary care hospital, between 2003 and 2014, with median length of follow-up of 2.2 years (range 0.1-9.3 years). Pediatric patients (<18 years old at time of surgical procedure) who had current procedural terminology (CPT) codes of OCR, and available pre- and post-operative audiograms were included in the study. Demographic information, surgical details, and pre- and post-operative pure-tone averages (PTA), speech reception thresholds (SRT), and air-bone gaps (ABG) were recorded from clinic notes, audiograms and operative reports. Differences between PTA, SRT and ABG pre- and post-operatively, as well as demographic and surgical factors, were evaluated using Wilcoxon rank-sum tests. Factors influencing revision were evaluated using Log-rank tests. RESULTS: A total of 120 patients (123 ears) were included. 35.8% of cases were revised, most commonly due to displaced prostheses. 28.5% of surgeries resulted in normal hearing (PTA ≤25 dB) post-operatively. Post-operative SRT and ABG were significantly better in patients with partial ossicular replacement prosthesis (PORP) compared with those with total ossicular replacement prosthesis (TORP) (p = 0.016, 0.027). Titanium prostheses resulted in better post-operative PTA and larger changes in PTA compared with all other materials (p = 0.034, p = 0.038). CONCLUSIONS: In our experience, children with titanium prostheses had better hearing outcomes than those with other materials, and children with PORP had better hearing outcomes than those with TORP.
[Mh] Termos MeSH primário: Ossículos da Orelha/cirurgia
Perda Auditiva Condutiva/cirurgia
Prótese Ossicular/efeitos adversos
Substituição Ossicular/métodos
[Mh] Termos MeSH secundário: Adolescente
Criança
Pré-Escolar
Feminino
Seguimentos
Audição/fisiologia
Testes Auditivos
Seres Humanos
Masculino
Estudos Retrospectivos
Titânio/uso terapêutico
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
D1JT611TNE (Titanium)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170803
[Lr] Data última revisão:
170803
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170710
[St] Status:MEDLINE



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