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[PMID]:28483240
[Au] Autor:Skarzynski PH; Raj-Koziak D; Rajchel JJ; Skarzynski H
[Ad] Endereço:World Hearing Center, Institute of Physiology and Pathology of Hearing, Warsaw, Kajetany, Poland; Heart Failure and Cardiac Rehabilitation Department, Medical University of Warsaw, Warsaw, Poland; Institute of Sensory Organs, Warsaw, Kajetany, Poland. Electronic address: p.skarzynski@ifps.org.pl.
[Ti] Título:Management of non-organic hearing loss in children - A case study.
[So] Source:Int J Pediatr Otorhinolaryngol;97:223-227, 2017 Jun.
[Is] ISSN:1872-8464
[Cp] País de publicação:Ireland
[La] Idioma:eng
[Ab] Resumo:A 10 year-old girl was admitted due to the claim of progressively developing hearing loss. The impedance audiometry showed no abnormalities but it was impossible to obtain reliable outcomes during pure tone audiometry assessment. The girl was additionally sent for speech audiometry, indicating a bilateral hearing loss and objective evaluations such as distortion product otoacoustic emissions and auditory brainstem responses, which results indicated a normal hearing. On the second day, repeated subjective audiometric tests showed also normal hearing, despite constantly reported hearing loss. After the psychological consultation and exclusion of neurologic pathology, the diagnosis of non-organic hearing loss was stated and the girl was scheduled for regular appointments with psychologist.
[Mh] Termos MeSH primário: Perda Auditiva Funcional/diagnóstico
[Mh] Termos MeSH secundário: Audiometria/métodos
Criança
Feminino
Seres Humanos
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170718
[Lr] Data última revisão:
170718
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170510
[St] Status:MEDLINE


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[PMID]:27808008
[Au] Autor:Mistry SG; Carr SD; Tapper L; Meredith B; Strachan DR; Raine CH
[Ad] Endereço:a Yorkshire Auditory Implant Service, Bradford Royal Infirmary , Duckworth Lane, Bradford BD9 6RJ , UK.
[Ti] Título:Inside implant criteria or not? - Detection of non-organic hearing loss during cochlear implant assessment.
[So] Source:Cochlear Implants Int;17(6):276-282, 2016 Nov.
[Is] ISSN:1754-7628
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: The diagnosis of non-organic hearing loss (NOHL) is a difficult but important issue during the assessment process for cochlear implantation (CI). We aim to identify the key factors in identifying patients with NOHL during CI assessment and present our local screening protocol for NOHL. METHODS: A retrospective review of patients referred to the Yorkshire Auditory Implant Service (YAIS) between 2003 and 2015 who were subsequently diagnosed with NOHL during the assessment. Patient demographic data, audiological and functional assessments were assessed. RESULTS: Thirty-two patients were included in the study. Mean age was 43 years (range 14-82 years). Male to female ratio was 1:1.7. Indicators of possible NOHL included a sudden deterioration in hearing (n = 21; 66%), mismatches in observed behaviour and either pure-tone audiogram (PTA) (n = 27; 84%) or functional testing (n = 20; 80%) and stapedial reflexes below reported audiological thresholds (n = 12; 46%). A mismatch in functional hearing and PTA was seen in 72% of patients. Patients with suspected NOHL were referred for further objective testing. All 23 patients who underwent objective testing had better hearing levels compared to reported hearing thresholds thus placing them outside of implant criteria. Five candidates were found to have normal hearing thresholds. DISCUSSION: NOHL can present a significant challenge to the implant team, particularly in the subgroup with a pre-existing organic hearing loss with non-organic overlay. We discuss the common features in this cohort of patients. CONCLUSIONS: To facilitate the identification of patients with NOHL, the YAIS has developed a screening protocol.
[Mh] Termos MeSH primário: Audiometria de Tons Puros/estatística & dados numéricos
Implante Coclear
Perda Auditiva Funcional/diagnóstico
Seleção de Pacientes
Avaliação de Sintomas/métodos
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Idoso de 80 Anos ou mais
Limiar Auditivo
Feminino
Perda Auditiva Funcional/fisiopatologia
Perda Auditiva Funcional/cirurgia
Seres Humanos
Masculino
Meia-Idade
Período Pré-Operatório
Valores de Referência
Estudos Retrospectivos
Estribo/fisiopatologia
Avaliação de Sintomas/estatística & dados numéricos
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170906
[Lr] Data última revisão:
170906
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161104
[St] Status:MEDLINE
[do] DOI:10.1080/14670100.2016.1249993


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[PMID]:26864517
[Au] Autor:García-García G; Baux D; Faugère V; Moclyn M; Koenig M; Claustres M; Roux AF
[Ad] Endereço:Laboratoire de génétique de maladies rares, EA 7402, Université de Montpellier, Montpellier, France.
[Ti] Título:Assessment of the latest NGS enrichment capture methods in clinical context.
[So] Source:Sci Rep;6:20948, 2016 Feb 11.
[Is] ISSN:2045-2322
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Enrichment capture methods for NGS are widely used, however, they evolve rapidly and it is necessary to periodically measure their strengths and weaknesses before transfer to diagnostic services. We assessed two recently released custom DNA solution-capture enrichment methods for NGS, namely Illumina NRCCE and Agilent SureSelect(QXT), against a reference method NimbleGen SeqCap EZ Choice on a similar gene panel, sharing 678 kb and 110 genes. Two Illumina MiSeq runs of 12 samples each have been performed, for each of the three methods, using the same 24 patients (affected with sensorineural disorders). Technical outcomes have been computed and compared, including depth and evenness of coverage, enrichment in targeted regions, performance in GC-rich regions and ability to generate consistent variant datasets. While we show that the three methods resulted in suitable datasets for standard DNA variant discovery, we describe significant differences between the results for the above parameters. NimbleGen offered the best depth of coverage and evenness, while NRCCE showed the highest on target levels but high duplicate rates. SureSelect(QXT) showed an overall quality close to that of NimbleGen. The new methods exhibit reduced preparation time but behave differently. These findings will guide laboratories in their choice of library enrichment approach.
[Mh] Termos MeSH primário: Perda Auditiva Funcional/genética
Sequenciamento de Nucleotídeos em Larga Escala/métodos
Retinite Pigmentosa/genética
Síndromes de Usher/genética
[Mh] Termos MeSH secundário: Composição de Bases
Genes Recessivos
Perda Auditiva Funcional/diagnóstico
Sequenciamento de Nucleotídeos em Larga Escala/instrumentação
Seres Humanos
Retinite Pigmentosa/diagnóstico
Análise de Sequência de DNA
Síndromes de Usher/diagnóstico
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1612
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160212
[St] Status:MEDLINE
[do] DOI:10.1038/srep20948


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[PMID]:26669464
[Ti] Título:[In Process Citation].
[Ti] Título:Fragen für die Facharztprüfung..
[So] Source:Laryngorhinootologie;94(12):870, 2015 Dec.
[Is] ISSN:1438-8685
[Cp] País de publicação:Germany
[La] Idioma:ger
[Mh] Termos MeSH primário: Surdez/diagnóstico
Transtornos Autoinduzidos/diagnóstico
Perda Auditiva Funcional/diagnóstico
Tonsila Palatina/patologia
[Mh] Termos MeSH secundário: Testes Auditivos
Seres Humanos
Hiperplasia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1610
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151217
[St] Status:MEDLINE
[do] DOI:10.1055/s-0035-1552391


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[PMID]:26564979
[Au] Autor:Bhattacharya A; Cui Y
[Ad] Endereço:Department of Microbiology, Immunology and Biochemistry and Center for Integrative and Translational Genomics, University of Tennessee Health Science Center, Memphis, TN 38163, USA, abhatta3@uthsc.edu.
[Ti] Título:Knowledge-based analysis of functional impacts of mutations in microRNA seed regions.
[So] Source:J Biosci;40(4):791-8, 2015 Oct.
[Is] ISSN:0973-7138
[Cp] País de publicação:India
[La] Idioma:eng
[Ab] Resumo:MicroRNAs are a class of important post-transcriptional regulators. Genetic and somatic mutations in miRNAs, especially those in the seed regions, have profound and broad impacts on gene expression and physiological and pathological processes. Over 500 SNPs were mapped to the miRNA seeds, which are located at position 2-8 of the mature miRNA sequences. We found that the central positions of the miRNA seeds contain fewer genetic variants and therefore are more evolutionary conserved than the peripheral positions in the seeds. We developed a knowledgebased method to analyse the functional impacts of mutations in miRNA seed regions. We computed the gene ontology-based similarity score GOSS and the GOSS percentile score for all 517 SNPs in miRNA seeds. In addition to the annotation of SNPs for their functional effects, in the present article we also present a detailed analysis pipeline for finding the key functional changes for seed SNPs. We performed a detailed gene ontology graph-based analysis of enriched functional categories for miRNA target gene sets. In the analysis of a SNP in the seed region of hsa-miR-96 we found that two key biological processes for progressive hearing loss 'Neurotrophin TRK receptor signaling pathway' and 'Epidermal growth factor receptor signaling pathway' were significantly and differentially enriched by the two sets of allele-specific target genes of miRNA hsa-miR-96.
[Mh] Termos MeSH primário: Algoritmos
Perda Auditiva Funcional/genética
MicroRNAs/genética
Polimorfismo de Nucleotídeo Único
Receptor do Fator de Crescimento Epidérmico/genética
Receptor trkA/genética
[Mh] Termos MeSH secundário: Alelos
Perfilação da Expressão Gênica
Regulação da Expressão Gênica
Ontologia Genética
Perda Auditiva Funcional/metabolismo
Perda Auditiva Funcional/patologia
Seres Humanos
MicroRNAs/metabolismo
Anotação de Sequência Molecular
Mutação
Receptor do Fator de Crescimento Epidérmico/metabolismo
Receptor trkA/metabolismo
Transdução de Sinais
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (MIRN96 microRNA, human); 0 (MicroRNAs); EC 2.7.10.1 (Receptor, Epidermal Growth Factor); EC 2.7.10.1 (Receptor, trkA)
[Em] Mês de entrada:1608
[Cu] Atualização por classe:171108
[Lr] Data última revisão:
171108
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151114
[St] Status:MEDLINE


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[PMID]:25740258
[Au] Autor:Kompis M; Senn P; Mantokoudis G; Caversaccio M
[Ad] Endereço:Department of ENT, Head and Neck Surgery, Inselspital, University of Bern , Bern , Switzerland.
[Ti] Título:Cochlear implant candidates with psychogenic hearing loss.
[So] Source:Acta Otolaryngol;135(4):376-80, 2015 Apr.
[Is] ISSN:1651-2251
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:CONCLUSIONS: Specific requests for cochlear implantations by persons with psychogenic hearing loss are a relatively new phenomenon. A number of features seems to be over-represented in this group of patients. The existence of these requests stresses the importance of auditory brainstem response (ABR) measurements before cochlear implantation. OBJECTIVE: To describe the phenomenon of patients with psychogenic hearing losses specifically requesting cochlear implantation, and to gain first insights into the characteristics of this group. METHODS: Analysis of all cases seen between 2004 and 2013 at the University Hospital of Bern, Switzerland. RESULTS: Four cochlear implant candidates with psychogenic hearing loss were identified. All were female, aged 23-51 years. Hearing thresholds ranged from 86 dB to 112 dB HL (pure-tone average 500-4000 Hz). ABRs and otoacoustic emissions (OAEs) showed bilaterally normal hearing in two subjects, and hearing thresholds between 30 and 50 dB in the other two subjects. Three subjects suffered from depression and one from a pathologic fear of cancer. Three had a history of five or more previous surgeries. Three were smokers and three reported other close family members with hearing losses. All four were hearing aid users at the time of presentation.
[Mh] Termos MeSH primário: Implante Coclear
Implantes Cocleares
Perda Auditiva Funcional/diagnóstico
Perda Auditiva Funcional/psicologia
Emissões Otoacústicas Espontâneas/fisiologia
[Mh] Termos MeSH secundário: Adulto
Audiometria
Transtorno Depressivo/complicações
Potenciais Evocados Auditivos do Tronco Encefálico
Feminino
Comportamentos Relacionados com a Saúde
Perda Auditiva Funcional/terapia
Seres Humanos
Meia-Idade
Neoplasias/psicologia
Suíça
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1512
[Cu] Atualização por classe:150313
[Lr] Data última revisão:
150313
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150306
[St] Status:MEDLINE
[do] DOI:10.3109/00016489.2014.985801


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[PMID]:25421175
[Au] Autor:Schlauch RS; Koerner TK; Marshall L
[Ti] Título:Effective identification of functional hearing loss using behavioral threshold measures.
[So] Source:J Speech Lang Hear Res;58(2):453-65, 2015 Apr.
[Is] ISSN:1558-9102
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PURPOSE: Four functional hearing loss protocols were evaluated. METHOD: For each protocol, 30 participants feigned a hearing loss first on an audiogram and then for a screening test that began a threshold search from extreme levels (-10 or 90 dB HL). Two-tone and 3-tone protocols compared thresholds for ascending and descending tones for 2 (0.5 and 1.0 kHz) and 3 (0.5, 1.0, and 2.0 kHz) frequencies, respectively. A noise-band protocol compared an ascending noise-band threshold with that for 2 descending tones (0.5 and 1.0 kHz). A spondee protocol compared an ascending spondee threshold with that for 2 descending tones (0.5 and 1.0 kHz). These measures were repeated without the participants feigning losses. RESULTS: With nonfeigning participants, ascending and descending threshold differences were minimal for all protocols. When the participants feigned a loss, the spondee protocol produced the largest average threshold difference (30.8 dB), whereas the other protocols produced smaller differences (19.6-22.2 dB). CONCLUSIONS: Using both the screening test and a comparison of the initial audiogram with the screening test, the spondee and 3-tone protocols resulted in 100% true positives and 0% false positives for functional hearing loss. Either of these protocols could be used clinically or in occupational hearing conservation programs.
[Mh] Termos MeSH primário: Perda Auditiva Funcional/diagnóstico
Testes Auditivos/métodos
[Mh] Termos MeSH secundário: Estimulação Acústica/métodos
Adulto
Audiometria de Tons Puros/métodos
Limiar Auditivo
Feminino
Seres Humanos
Masculino
Ruído
Psicoacústica
[Pt] Tipo de publicação:EVALUATION STUDIES; JOURNAL ARTICLE; RESEARCH SUPPORT, U.S. GOV'T, NON-P.H.S.
[Em] Mês de entrada:1612
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:141126
[St] Status:MEDLINE
[do] DOI:10.1044/2014_JSLHR-H-14-0066


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[PMID]:25287617
[Au] Autor:Raveh D; Lavie N
[Ad] Endereço:Institute of Cognitive Neuroscience, University College London, London, United Kingdom, d.raveh@ucl.ac.uk.
[Ti] Título:Load-induced inattentional deafness.
[So] Source:Atten Percept Psychophys;77(2):483-92, 2015 Feb.
[Is] ISSN:1943-393X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:High perceptual load in a task is known to reduce the visual perception of unattended items (e.g., Lavie, Beck, & Konstantinou, 2014). However, it remains an open question whether perceptual load in one modality (e.g., vision) can affect the detection of stimuli in another modality (e.g., hearing). We report four experiments that establish that high visual perceptual load leads to reduced detection sensitivity in hearing. Participants were requested to detect a tone that was presented during performance of a visual search task of either low or high perceptual load (varied through item similarity). The findings revealed that auditory detection sensitivity was consistently reduced with higher load, and that this effect persisted even when the auditory detection response was made first (before the search response) and when the auditory stimulus was highly expected (50 % present). These findings demonstrate a phenomenon of load-induced deafness and provide evidence for shared attentional capacity across vision and hearing.
[Mh] Termos MeSH primário: Atenção/fisiologia
Percepção Auditiva/fisiologia
Perda Auditiva Funcional/fisiopatologia
Percepção Visual/fisiologia
[Mh] Termos MeSH secundário: Adulto
Feminino
Seres Humanos
Masculino
Meia-Idade
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1508
[Cu] Atualização por classe:160218
[Lr] Data última revisão:
160218
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:141008
[St] Status:MEDLINE
[do] DOI:10.3758/s13414-014-0776-2


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[PMID]:25184702
[Au] Autor:Wolber LE; Steves CJ; Tsai PC; Deloukas P; Spector TD; Bell JT; Williams FM
[Ad] Endereço:Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom.
[Ti] Título:Epigenome-wide DNA methylation in hearing ability: new mechanisms for an old problem.
[So] Source:PLoS One;9(9):e105729, 2014.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Epigenetic regulation of gene expression has been shown to change over time and may be associated with environmental exposures in common complex traits. Age-related hearing impairment is a complex disorder, known to be heritable, with heritability estimates of 57-70%. Epigenetic regulation might explain the observed difference in age of onset and magnitude of hearing impairment with age. Epigenetic epidemiology studies using unrelated samples can be limited in their ability to detect small effects, and recent epigenetic findings in twins underscore the power of this well matched study design. We investigated the association between venous blood DNA methylation epigenome-wide and hearing ability. Pure-tone audiometry (PTA) and Illumina HumanMethylation array data were obtained from female twin volunteers enrolled in the TwinsUK register. Two study groups were explored: first, an epigenome-wide association scan (EWAS) was performed in a discovery sample (n=115 subjects, age range: 47-83 years, Illumina 27 k array), then replication of the top ten associated probes from the discovery EWAS was attempted in a second unrelated sample (n=203, age range: 41-86 years, Illumina 450 k array). Finally, a set of monozygotic (MZ) twin pairs (n = 21 pairs) within the discovery sample (Illumina 27 k array) was investigated in more detail in an MZ discordance analysis. Hearing ability was strongly associated with DNA methylation levels in the promoter regions of several genes, including TCF25 (cg01161216, p = 6.6 × 10(-6)), FGFR1 (cg15791248, p = 5.7 × 10(-5) and POLE (cg18877514, p= 6.3 × 10(-5)). Replication of these results in a second sample confirmed the presence of differential methylation at TCF25 (p(replication)=6 × 10(-5)) and POLE (p(replication) =0.016). In the MZ discordance analysis, twins' intrapair difference in hearing ability correlated with DNA methylation differences at ACP6 (cg01377755, r= -0.75, p=1.2 × 10(-4)) and MEF2D (cg08156349, r= -0.75, p=1.4 × 10(-4)). Examination of gene expression in skin, suggests an influence of differential methylation on expression, which may account for the variation in hearing ability with age.
[Mh] Termos MeSH primário: Envelhecimento/sangue
Fatores de Transcrição Hélice-Alça-Hélice Básicos/genética
DNA Polimerase II/genética
Epigênese Genética
Perda Auditiva Funcional/sangue
Receptor Tipo 1 de Fator de Crescimento de Fibroblastos/genética
Proteínas Repressoras/genética
[Mh] Termos MeSH secundário: Fosfatase Ácida/sangue
Fosfatase Ácida/genética
Idoso
Idoso de 80 Anos ou mais
Envelhecimento/genética
Envelhecimento/patologia
Audiometria de Tons Puros
Fatores de Transcrição Hélice-Alça-Hélice Básicos/sangue
Metilação de DNA
DNA Polimerase II/sangue
Feminino
Genoma Humano
Perda Auditiva Funcional/genética
Perda Auditiva Funcional/fisiopatologia
Seres Humanos
Fatores de Transcrição MEF2/sangue
Fatores de Transcrição MEF2/genética
Meia-Idade
Proteínas de Ligação a Poli-ADP-Ribose
Regiões Promotoras Genéticas
Característica Quantitativa Herdável
Receptor Tipo 1 de Fator de Crescimento de Fibroblastos/sangue
Proteínas Repressoras/sangue
Gêmeos Monozigóticos/genética
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Basic Helix-Loop-Helix Transcription Factors); 0 (MEF2 Transcription Factors); 0 (MEF2D protein, human); 0 (Poly-ADP-Ribose Binding Proteins); 0 (Repressor Proteins); 0 (TCF25 protein, human); EC 2.7.10.1 (FGFR1 protein, human); EC 2.7.10.1 (Receptor, Fibroblast Growth Factor, Type 1); EC 2.7.7.- (DNA Polymerase II); EC 2.7.7.7 (POLE protein, human); EC 3.1.3.2 (Acid Phosphatase); EC 3.1.3.2 (acid phosphatase-like protein 1, human)
[Em] Mês de entrada:1505
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140904
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0105729


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[PMID]:25112166
[Au] Autor:Drouillard M; Petroff N; Majer J; Perrot C; Quesnel S; François M; ORL et CCF, CHU Robert Debré, Paris, France
[Ad] Endereço:APHP Groupe hospitalier Robert Debré, Pediatric Otorhinolaryngology Department, 75019 Paris, France; Université Paris 7, Denis Diderot, 5 rue Thomas Mann, 75013 Paris, France. Electronic address: mylene.dr@wanadoo.fr.
[Ti] Título:Pseudohypacusis in children: circumstances and diagnostic strategy.
[So] Source:Int J Pediatr Otorhinolaryngol;78(10):1632-6, 2014 Oct.
[Is] ISSN:1872-8464
[Cp] País de publicação:Ireland
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: The study attempts to specify the circumstances under which we should pay attention to children's pseudohypacusis. It evaluates the methods used to detect such cases and to determine hearing thresholds, according to the uni-or bilateralism of hearing loss. The study finally deals with the future of children diagnosed with pseudohypacusis. METHODS: The study was retrospective from January 1993 to November 2011 and prospective from December 2011 to April 2012. We included all the children between 3 and 16 years who were diagnosed with pseudohypacusis. We observed the reasons for them to consult, whether they had already been tested or had treatment, and what kind of hearing loss they displayed. All children were tested using standard pure tone audiometry and speech audiometry. Depending on the first results, other tests were conducted. They included transient evoked otoacoustic emissions (TEOEs), auditory brainstem responses (ABR) and auditory steady state responses. Families were finally contacted by phone over April 2012 in order to let them know about their child's results. RESULTS: Fifty-four children were included: 19 boys and 35 girls, with an average age of 10 year-old (±3). The simulated hearing loss (HL) was bilateral (36), unilateral (18), of perception (37), moderate HL (33), cophosis (5). Fifteen cases were linked to a family or personal history of hearing loss, while 27 cases were due to important events like adoption, abuse, verbal aggression, school problems. Before diagnosing a pseudohypacusis, 13 children had had imaging studies, 3 had been treated with corticosteroids, and 5 had hearing aids. Most of the time the presence of pseudohypacusis was suspected a discrepancy between speech reception and air-conduction pure tone thresholds, as shown by the medical test (answer on whispered voice). The diagnosis was confirmed by ABR or TEOEs, except in cases where clinic was obvious. Then family's patient and patient were reassured and informed. An audiological follow-up during either 6 months or 1 year was proposed, as well as a psychological consultation. CONCLUSION: Complementary examinations have to be performed to rule out a pseudohypacusis case before suggesting an invasive or expensive treatment (surgery or hearing aids) of children.
[Mh] Termos MeSH primário: Perda Auditiva Funcional/diagnóstico
Audição/fisiologia
[Mh] Termos MeSH secundário: Adolescente
Audiometria de Tons Puros
Audiometria da Fala
Criança
Pré-Escolar
Potenciais Evocados Auditivos do Tronco Encefálico/fisiologia
Feminino
Auxiliares de Audição
Perda Auditiva Funcional/etiologia
Seres Humanos
Masculino
Estudos Prospectivos
Estudos Retrospectivos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1601
[Cu] Atualização por classe:140911
[Lr] Data última revisão:
140911
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140813
[St] Status:MEDLINE



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