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  1 / 2013 MEDLINE  
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[PMID]:29173202
[Au] Autor:Unadkat S; Kanzara T; Watters G
[Ad] Endereço:Department of Otolaryngology,Southend University Hospitals NHS Trust,UK.
[Ti] Título:Necrotising otitis externa in the immunocompetent patient: case series.
[So] Source:J Laryngol Otol;132(1):71-74, 2018 Jan.
[Is] ISSN:1748-5460
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Necrotising otitis externa can be a devastating form of otitis externa. It typically tends to affect patients who are immunocompromised or diabetic. To date, there is very little in the literature about necrotising otitis externa in the immunocompetent patient population. CASE REPORTS: The present paper discusses both the clinical and radiological findings in three cases of necrotising otitis externa in an immunocompetent patient cohort. The common factor among all three patients was their advanced age. CONCLUSION: Diagnosing necrotising otitis externa can be challenging because of the potentially non-specific symptoms and the absence of early radiological signs, particularly if patients are neither immunocompromised nor diabetic. Elderly patients should be considered in the same light as immunocompromised and diabetic patients in the context of necrotising otitis externa.
[Mh] Termos MeSH primário: Antibacterianos/uso terapêutico
Hospedeiro Imunocomprometido
Otite Externa/diagnóstico
Infecções por Pseudomonas/diagnóstico
[Mh] Termos MeSH secundário: Idoso de 80 Anos ou mais
Biópsia
Diagnóstico Diferencial
Feminino
Seres Humanos
Imagem por Ressonância Magnética
Masculino
Otite Externa/microbiologia
Otite Externa/terapia
Infecções por Pseudomonas/microbiologia
Pseudomonas aeruginosa/isolamento & purificação
Estudos Retrospectivos
Tomografia Computadorizada por Raios X
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Bacterial Agents)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180104
[Lr] Data última revisão:
180104
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171128
[St] Status:MEDLINE
[do] DOI:10.1017/S0022215117002237


  2 / 2013 MEDLINE  
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[PMID]:28695767
[Au] Autor:Henatsch D; Nabuurs CH; van de Goor RM; Wolffs PF; Stokroos RJ
[Ad] Endereço:1 Department of Otorhinolaryngology-Head and Neck Surgery, Maastricht University Medical Center+, Maastricht, The Netherlands.
[Ti] Título:Treatment of Recurrent Eczematous External Otitis with Honey Eardrops: A Proof-of-Concept Study.
[So] Source:Otolaryngol Head Neck Surg;157(4):696-699, 2017 Oct.
[Is] ISSN:1097-6817
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Eczematous external otitis is a chronic inflammatory disease and often difficult to treat. Our objective was to investigate the clinical effect and in vitro antibacterial potential of medical honey eardrops as treatment of eczematous external otitis. In a prospective study, 15 patients diagnosed with recurrent eczematous external otitis were treated with medical honey eardrops for 2 weeks. The following clinical outcomes were evaluated: visual analog scale of ear complaints, score of eczema, and eradication of bacterial infection. Furthermore, the antibacterial effect of honey eardrops against different bacterial strains was tested in vitro. Treatment resulted in less discomfort and itching and decreased signs of eczema, with high patient satisfaction and without adverse reactions. Honey eardrops showed a strong in vitro inhibitory activity against all tested strains but did not eradicate Staphylococcus aureus infection in vivo. The results of this preliminary study indicate a possible role of honey eardrops in eczematous ear disease.
[Mh] Termos MeSH primário: Eczema/terapia
Mel
Otite Externa/terapia
[Mh] Termos MeSH secundário: Administração Tópica
Idoso
Idoso de 80 Anos ou mais
Eczema/complicações
Feminino
Seguimentos
Seres Humanos
Masculino
Meia-Idade
Otite Externa/complicações
Estudos Prospectivos
Recidiva
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171012
[Lr] Data última revisão:
171012
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170712
[St] Status:MEDLINE
[do] DOI:10.1177/0194599817718782


  3 / 2013 MEDLINE  
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[PMID]:28693628
[Au] Autor:Bola S; Rashid M; Hickey S
[Ad] Endereço:Department of Otolaryngology,Torbay and South Devon NHS Foundation Trust,Torquay,UK.
[Ti] Título:Optimising the use of otowicks in otitis externa.
[So] Source:J Laryngol Otol;131(9):809-812, 2017 Sep.
[Is] ISSN:1748-5460
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: Otowicks are used to treat otitis externa with significant ear canal oedema. This study investigates how well drops penetrate through to reach the deep canal and whether it is safe to leave otowicks in the canal for more than 2 days. METHODS: Sterile otowicks were inserted into mock ear canals and vertically over pseudomonas-seeded agar plates whilst gentamicin or ciprofloxacin drops were administered. The time taken for drops to penetrate through the otowick was recorded. Separately, pseudomonas-seeded otowicks were treated with saline or antibacterial drops. The penetrating drops were observed for bacterial growth on sterile agar. RESULTS: It took six drops before penetration occurred for both antibiotics. When sterile saline drops were applied to bacterially contaminated otowicks, the penetrating drops displayed bacterial growth on agar, indicating that pseudomonas penetrated through the otowick. However, when antibiotic drops were applied, penetrating drops showed no bacterial growth on the corresponding agar plate. CONCLUSION: Bacteria can penetrate otowicks but this is prevented by continuous application of antibacterial ear drops. Ear wicks need priming with six drops before starting a regimen, so that the initial dose is fully absorbed.
[Mh] Termos MeSH primário: Ciprofloxacino/administração & dosagem
Gentamicinas/administração & dosagem
Otite Externa/tratamento farmacológico
[Mh] Termos MeSH secundário: Portadores de Fármacos
Seres Humanos
Instilação de Medicamentos
Otite Externa/metabolismo
Tampões Cirúrgicos
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Drug Carriers); 0 (Gentamicins); 5E8K9I0O4U (Ciprofloxacin)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170915
[Lr] Data última revisão:
170915
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170712
[St] Status:MEDLINE
[do] DOI:10.1017/S002221511700144X


  4 / 2013 MEDLINE  
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[PMID]:28641322
[Au] Autor:Livingstone DM; Smith KA; Lange B
[Ad] Endereço:Division of Otolaryngology - Head and Neck Surgery, Department of Surgery, University of Calgary, 7th floor, 4448 Front Street SE, Calgary, Alberta, Canada, T3M 1M4, dmliving@ucalgary.ca.
[Ti] Título:Scuba diving and otology: a systematic review with recommendations on diagnosis, treatment and post-operative care.
[So] Source:Diving Hyperb Med;47(2):97-109, 2017 Jun.
[Is] ISSN:1833-3516
[Cp] País de publicação:Australia
[La] Idioma:eng
[Ab] Resumo:Scuba diving is a popular recreational and professional activity with inherent risks. Complications related to barotrauma and decompression illness can pose significant morbidity to a diver's hearing and balance systems. The majority of dive-related injuries affect the head and neck, particularly the outer, middle and inner ear. Given the high incidence of otologic complications from diving, an evidence-based approach to the diagnosis and treatment of otic pathology is a necessity. We performed a systematic and comprehensive literature review including the pathophysiology, diagnosis, and treatment of otologic pathology related to diving. This included inner, middle, and outer ear anatomic subsites, as well as facial nerve complications, mal de debarquement syndrome, sea sickness and fitness to dive recommendations following otologic surgery. Sixty-two papers on diving and otologic pathology were included in the final analysis. We created a set of succinct evidence-based recommendations on each topic that should inform clinical decisions by otolaryngologists, dive medicine specialists and primary care providers when faced with diving-related patient pathology.
[Mh] Termos MeSH primário: Barotrauma
Fenômenos Biofísicos
Doença da Descompressão
Mergulho/lesões
Otopatias
[Mh] Termos MeSH secundário: Barotrauma/diagnóstico
Barotrauma/etiologia
Barotrauma/terapia
Doença da Descompressão/diagnóstico
Doença da Descompressão/etiologia
Doença da Descompressão/terapia
Mergulho/efeitos adversos
Otopatias/diagnóstico
Otopatias/etiologia
Otopatias/terapia
Orelha Interna
Orelha Média
Exostose/diagnóstico
Exostose/terapia
Seres Humanos
Otite Externa/etiologia
Otite Externa/terapia
Equilíbrio Postural
Transtornos das Sensações/etiologia
Transtornos das Sensações/terapia
Vertigem/etiologia
Vertigem/terapia
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170808
[Lr] Data última revisão:
170808
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170623
[St] Status:MEDLINE


  5 / 2013 MEDLINE  
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[PMID]:28528568
[Au] Autor:Hasibi M; Ashtiani MK; Motassadi Zarandi M; Yazdani N; Borghei P; Kuhi A; Dabiri S; Hosseini R; Sardashti S
[Ad] Endereço:1 Amir-Alam Hospital, Tehran, Iran, Islamic Republic Of.
[Ti] Título:A Treatment Protocol for Management of Bacterial and Fungal Malignant External Otitis: A Large Cohort in Tehran, Iran.
[So] Source:Ann Otol Rhinol Laryngol;126(7):561-567, 2017 Jul.
[Is] ISSN:1943-572X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:AIMS: High rates of negative microbiologic test results highlight the potential role of empiric antimicrobial agents in management of malignant otitis externa (MOE). This study investigates the clinical presentation, laboratory findings, and response to empiric treatment in a large group of patients admitted to a tertiary academic hospital in Tehran, Iran. METHODS AND MATERIALS: We recruited 224 patients diagnosed with MOE in a prospective observation from 2009 through 2015. All patients received a 2-agent antibacterial regimen at baseline (phase I). Patients with no improvement within 10 days and/or nonresponders to a second course of antibacterials were switched to antifungals (phase II). Response to treatment was observed and documented in both groups. RESULTS: All patients had physical symptoms for more than 12 weeks before admission. In total, 127 patients responded well to antibacterials. Eighty-seven out of 97 patients who were switched to antifungals had complete response to treatment; patients in the latter group had significantly higher A1C levels at baseline. CONCLUSION: Our findings provide evidence to develop clinical guidelines that accelerate diagnosis and treatment of MOE to improve patient outcomes.
[Mh] Termos MeSH primário: Infecções Bacterianas/tratamento farmacológico
Micoses/tratamento farmacológico
Osteomielite/tratamento farmacológico
Osteomielite/microbiologia
Otite Externa/tratamento farmacológico
Otite Externa/microbiologia
Base do Crânio/microbiologia
[Mh] Termos MeSH secundário: Idoso
Idoso de 80 Anos ou mais
Antibacterianos/efeitos adversos
Antibacterianos/uso terapêutico
Antifúngicos/efeitos adversos
Antifúngicos/uso terapêutico
Lista de Checagem
Protocolos Clínicos
Seres Humanos
Irã (Geográfico)
Meia-Idade
Osteomielite/diagnóstico
Otite Externa/diagnóstico
Estudos Prospectivos
Centros de Atenção Terciária
[Pt] Tipo de publicação:JOURNAL ARTICLE; OBSERVATIONAL STUDY
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); 0 (Antifungal Agents)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170821
[Lr] Data última revisão:
170821
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170523
[St] Status:MEDLINE
[do] DOI:10.1177/0003489417710473


  6 / 2013 MEDLINE  
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[PMID]:28357818
[Au] Autor:Wingelaar TT; van Ooij PA; van Hulst RA
[Ad] Endereço:Royal Netherlands Navy Diving Medical Center, Rijkszee en marinehaven, 1780 CA Den Helder, The Netherlands tt.wingelaar@mindef.nl.
[Ti] Título:Otitis externa in military divers: more frequent and less harmful than reported.
[So] Source:Diving Hyperb Med;47(1):4-8, 2017 Mar.
[Is] ISSN:1833-3516
[Cp] País de publicação:Australia
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: Although otitis externa (OE) is a common disease, data related to (military) divers are limited. This study aimed to determine the incidence of OE in military divers during their initial training. We also wished to consider seasonal influences on incidence and whether early detection increases completion of the diving course. METHODS: From January 2011 to October 2016 the Royal Netherlands Navy Diving School trained 189 divers. Up to December 2015 we used the training records for the analyses. From January 2016 onward all divers were prospectively screened. Pearson's chi-squared 2 and Fisher's exact tests were used to analyse the data. RESULTS: In the 162 included divers, 30 cases of OE were identified. The incidence in 2016 was significantly higher than in 2011-2015 (17/35 (49%) versus 13/127 (10%), P < 0.001). Almost all cases developed after three weeks of diving. No influence of season was found (P = 0.354). Early diagnosis and treatment of OE does not seem to affect completion of diving courses (P = 0.28). Only in three cases did a diver have to discontinue the course due to OE. DISCUSSION: This study suggests that OE is more frequent among military divers than earlier reported, most likely caused by prolonged water exposure. Diving activities can often be continued with standard topical treatment.
[Mh] Termos MeSH primário: Mergulho/estatística & dados numéricos
Militares/estatística & dados numéricos
Otite Externa/epidemiologia
[Mh] Termos MeSH secundário: Distribuição de Qui-Quadrado
Mergulho/efeitos adversos
Feminino
Seres Humanos
Incidência
Masculino
Países Baixos/epidemiologia
Otite Externa/etiologia
Estações do Ano
Estatísticas não Paramétricas
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170502
[Lr] Data última revisão:
170502
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170331
[St] Status:MEDLINE


  7 / 2013 MEDLINE  
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[PMID]:28348261
[Au] Autor:Bowles PF; Perkins V; Schechter E
[Ad] Endereço:Brighton and Sussex University Hospitals NHS Trust, Brighton, Brighton and Hove, UK.
[Ti] Título:Fungal malignant otitis externa.
[So] Source:BMJ Case Rep;2017, 2017 Mar 27.
[Is] ISSN:1757-790X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:An 89-year-old man presented to the outpatient clinic with a 2-month history of persistent unilateral left-sided otalgia, otorrhoea and reduced hearing despite oral and topical antibiotics. Treatment was protracted, requiring a 4-month hospital admission for intravenous antifungal medication as well as 3 further months of oral antifungal treatment. We describe the clinical presentation, complications and treatment of this potentially fatal condition in the context of an unusual, and easily missed, causative organism.
[Mh] Termos MeSH primário: Antifúngicos/administração & dosagem
Candidíase/diagnóstico
Otite Externa/microbiologia
[Mh] Termos MeSH secundário: Administração Intravenosa
Administração Oral
Idoso de 80 Anos ou mais
Antifúngicos/uso terapêutico
Candidíase/tratamento farmacológico
Seres Humanos
Masculino
Otite Externa/tratamento farmacológico
Resultado do Tratamento
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antifungal Agents)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170512
[Lr] Data última revisão:
170512
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170329
[St] Status:MEDLINE


  8 / 2013 MEDLINE  
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[PMID]:28252582
[Au] Autor:Nikiforova GN; Svistushkin VM; Shevchik AE; Zolotova AV
[Ad] Endereço:I.M. Sechenov First Moscow State Medical University, Moscow, Russia, 119991.
[Ti] Título:[Malignant externa otitis: the modern principles of diagnostics and treatment].
[Ti] Título:Zlokachestvennyi naruzhnyi otit: sovremennye printsipy diagnostiki i lecheniia..
[So] Source:Vestn Otorinolaringol;82(1):11-14, 2017.
[Is] ISSN:0042-4668
[Cp] País de publicação:Russia (Federation)
[La] Idioma:rus
[Ab] Resumo:The objective of the present study was to elucidate the specific features of the clinical course of malignant externa otitis in the context of the present-day concepts. A total of 5 patients presenting with the confirmed diagnosis of malignant external otitis were available for the examination. The analysis of the clinical observations provided the basis for the characteristic of pathogenesis of this condition, diagnostic principles, and treatment modalities for the management of the pathology in question. It is concluded that the patients suffering from malignant externa otitis must remain under medical care and observation during a long period and the strategy for the treatment of each concrete patient should be chosen on an individual basis taking into consideration the presence of concomitant pathologies and their adequate therapy.
[Mh] Termos MeSH primário: Otite Externa
[Mh] Termos MeSH secundário: Seres Humanos
Otite Externa/complicações
Otite Externa/diagnóstico
Otite Externa/patologia
Otite Externa/terapia
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170621
[Lr] Data última revisão:
170621
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170303
[St] Status:MEDLINE
[do] DOI:10.17116/otorino201782111-14


  9 / 2013 MEDLINE  
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[PMID]:28241842
[Au] Autor:Kaimio M; Saijonmaa-Koulumies L; Laitinen-Vapaavuori O
[Ad] Endereço:Department of Equine and Small Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, P.O. Box 57, 00014, Helsinki, Finland. mirja.kaimio@evidensia.fi.
[Ti] Título:Survey of otitis externa in American Cocker Spaniels in Finland.
[So] Source:Acta Vet Scand;59(1):14, 2017 Feb 28.
[Is] ISSN:1751-0147
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: American Cocker Spaniels are overrepresented among breeds that require surgery as a treatment of end-stage otitis externa. However, the prevalence of otitis externa (OE) in this breed remains unknown. We reviewed the year 2010 medical records of 55 private veterinary clinics in Finland to determine the prevalence of OE in American Cocker Spaniels compared with English Cocker and English and Welsh Springer Spaniels. An American Cocker Spaniel owner questionnaire was designed to identify potential risk factors for end-stage OE. RESULTS: From the medical records of 98,736 dogs, the prevalence of OE was highest in Welsh Springer Spaniels (149 out of 468, 31.8%, [95% confidence interval 27.6-36.0]), followed by American Cocker (89/329, 27.0%, [22.2-31.7]), English Springer (96/491, 19.6%, [16.1-23.1]) and English Cocker Spaniels (231/1467, 15.7%, [13.8-17.6]). The mean number of OE episodes in ear-diseased dogs and the number of ear surgeries were highest in American Cocker Spaniels. Owner questionnaires were received for 151 American Cocker Spaniels, 85 (56%) of which had suffered from OE. In 47% (40/85) of these dogs, OE occurred without concurrent skin lesions, 46% (33/72) displayed the first signs of OE before 1 year of age. In 24% (20/85) of the dogs, the signs of OE recurred within 1 month or continued despite treatment, 16% (14/85) required surgery (n = 11) or were euthanized (n = 5; 2 of the operated dogs and 3 others) due to severe OE. The onset of OE before the age of 1 year significantly increased the risk (OR 3.8, 95% CI 1.1-13.6) of end-stage OE. CONCLUSIONS: The prevalence of OE in American Cocker Spaniels in Finland was higher than previously reported in Cocker Spaniels, but the highest prevalence of OE was found in Welsh Springer Spaniels. Compared to the other Spaniels, OE was more often recurrent and more frequently surgically managed in American Cocker Spaniels. Based on the questionnaire, early onset (<1 year) of OE increased the risk of end-stage OE. In American Cocker Spaniels, OE requires an intensive approach from the first treatment, and prevention of recurrence should be emphasised. The causes and treatment of OE in this breed warrant further study.
[Mh] Termos MeSH primário: Doenças do Cão/epidemiologia
Otite Externa/veterinária
[Mh] Termos MeSH secundário: Animais
Cruzamento
Coleta de Dados
Doenças do Cão/tratamento farmacológico
Doenças do Cão/cirurgia
Cães
Finlândia/epidemiologia
Modelos Logísticos
Razão de Chances
Otite Externa/tratamento farmacológico
Otite Externa/epidemiologia
Otite Externa/cirurgia
Recidiva
Fatores de Risco
Inquéritos e Questionários
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170320
[Lr] Data última revisão:
170320
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170301
[St] Status:MEDLINE
[do] DOI:10.1186/s13028-017-0282-3


  10 / 2013 MEDLINE  
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[PMID]:28231368
[Au] Autor:Bhasker D; Hartley A; Agada F
[Ad] Endereço:Department of Otolaryngology-Head and Neck Surgery, York Teaching Hospital, NHS Foundation Trust, York, North Yorkshire, U.K. diana-bhasker@doctors.org.uk.
[Ti] Título:Is malignant otitis externa on the increase? A retrospective review of cases.
[So] Source:Ear Nose Throat J;96(2):E1-E5, 2017 Feb.
[Is] ISSN:1942-7522
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:We performed a retrospective review of all patients with malignant otitis externa (MOE) treated in our center between July 2004 and December 2012 to evaluate the current epidemiology in our region and to ascertain causative factors associated with the perceived increase in the number of cases diagnosed. Eleven patients were identified (5 men and 6 women), with a mean age of 77 years (range: 38 to 97 years). Diabetes was present in 36%. Pseudomonas aeruginosa was the causative organism in 64% of cases; all pathogens were sensitive to ciprofloxacin. We noted a significant increase in the diagnostic frequency of MOE during the study period (p = 0.0027) No obvious causative factors were identified. Due to the mortality associated with this condition, further studies are required to establish national trends.
[Mh] Termos MeSH primário: Otite Externa/microbiologia
Infecções por Pseudomonas/microbiologia
Pseudomonas aeruginosa
[Mh] Termos MeSH secundário: Adulto
Idoso
Idoso de 80 Anos ou mais
Antibacterianos/uso terapêutico
Ciprofloxacino/uso terapêutico
Feminino
Seres Humanos
Masculino
Meia-Idade
Otite Externa/tratamento farmacológico
Otite Externa/mortalidade
Infecções por Pseudomonas/tratamento farmacológico
Infecções por Pseudomonas/mortalidade
Estudos Retrospectivos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); 5E8K9I0O4U (Ciprofloxacin)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171002
[Lr] Data última revisão:
171002
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170224
[St] Status:MEDLINE



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