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[PMID]:29252405
[Au] Autor:Yoon JA; Shin YB; Shin MJ; Kang MS; Ko HY
[Ad] Endereço:From the Department of Rehabilitation Medicine, Pusan National University School of Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan, Republic of Korea (JAY, YBS, MJS); and Department of Rehabilitation Medicine, Pusan National University School of Medicine, Research Institute of Convergence for Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, Republic of Korea (MSK, H-YK).
[Ti] Título:Cardiovascular Monitoring During Video Urodynamic Studies in Persons With Spinal Cord Injury.
[So] Source:Am J Phys Med Rehabil;97(1):1-6, 2018 Jan.
[Is] ISSN:1537-7385
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: The aims of the study were to observe cardiovascular responses during video urodynamic studies and to identify correlations between autonomic dysreflexia events and video urodynamic study findings in spinal cord injuries. DESIGN: Thirty-four persons with spinal cord injury were enrolled and investigated using continuous cardiovascular monitoring during video urodynamic studies. Associations between cardiovascular responses and video study variables were analyzed. RESULTS: Bladder type-specific cardiovascular responses occurred during the study. The incidence of overactive detrusor during urodynamic study and bladder trabeculation on voiding cystourethrogram was significantly higher in autonomic dysreflexia persons with spinal cord injury (P < 0.05). Systolic blood pressure changes showed moderate negative correlation (r = -0.402, P = 0.020) with bladder compliance and high positive correlation (r = 0.810, P = 0.000) with maximum detrusor pressure. However, no significant differences in neurological level of injury, injury completeness, autonomic dysreflexia symptoms, and voiding type were found. Spinal cord injury increase at each section was significantly higher in overactive detrusor group (P < 0.05). Significant bradycardia or tachycardia correlating with autonomic dysreflexia during urodynamic studies was not observed. CONCLUSIONS: Unpredictable cardiovascular reactions during urodynamic study should be considered carefully in persons with a spinal cord injury above T6. TO CLAIM CME CREDITS: Complete the self-assessment activity and evaluation online at http://www.physiatry.org/JournalCME CME OBJECTIVES: Upon completion of this article, the reader should be able to: (1) Describe limitations of previous cardiovascular monitoring during urodynamic study to observe changes in cardiovascular responses; (2) Identify factors contributing to autonomic dysreflexia during urodynamic testing; and (3) Discuss the effect of morphologic features in voiding cystourethrogram including trabeculation and vesicourethral reflux on autonomic dysreflexia. LEVEL: Advanced ACCREDITATION: The Association of Academic Physiatrists is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.The Association of Academic Physiatrists designates this Journal-based CME activity for a maximum of 0.5 AMA PRA Category 1 Credit(s)™. Physicians should only claim credit commensurate with the extent of their participation in the activity.
[Mh] Termos MeSH primário: Disreflexia Autonômica/fisiopatologia
Doenças da Bexiga Urinária/etiologia
Urodinâmica
Gravação em Vídeo
[Mh] Termos MeSH secundário: Sistema Cardiovascular
Seres Humanos
Traumatismos da Medula Espinal/fisiopatologia
Doenças da Bexiga Urinária/fisiopatologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171227
[Lr] Data última revisão:
171227
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171219
[St] Status:MEDLINE
[do] DOI:10.1097/PHM.0000000000000839


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[PMID]:28174025
[Au] Autor:Kadekawa K; Yoshizawa T; Wada N; Shimizu T; Majima T; Tyagi P; de Groat WC; Sugaya K; Yoshimura N
[Ad] Endereço:Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Southern Knights' Laboratory, Okinawa, Japan; Okinawa Kyodo Hospital, Okinawa, Japan.
[Ti] Título:Effects of liposome-based local suppression of nerve growth factor in the bladder on autonomic dysreflexia during urinary bladder distention in rats with spinal cord injury.
[So] Source:Exp Neurol;291:44-50, 2017 May.
[Is] ISSN:1090-2430
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PURPOSE: To examine (1) whether spinal cord injury (SCI) time-dependently increases the severity of autonomic dysreflexia (AD) and expression levels of bladder nerve growth factor (NGF) protein, and (2) whether local suppression of NGF in the bladder improves SCI-induced AD in rats. MATERIALS AND METHODS: SCI was produced by the transection of the T2/3 spinal cord in female Sprague-Dawley rats. At 4 or 8weeks after SCI, differences in the mean arterial blood pressure (ΔMAP) and heart rate (ΔMHR) during graded increases in intravesical pressure to 20, 40 and 60cm H O from those before bladder distention and NGF protein levels in the bladder wall were evaluated in spinal intact and SCI rats under urethane anesthesia. Seven weeks after SCI liposome-NGF antisense conjugates were administered intravesically to the animals. At 1week after intravesical treatment (8weeks after SCI), ΔMAP and ΔMHR during bladder distention and bladder NGF protein expression were evaluated. RESULTS: The ΔMAP and ΔMHR were increased in a graded manner in response to bladder distention at intravesical pressures of 20, 40 and 60cm H O in SCI rats. These AD-like cardiovascular responses and NGF protein expression in the bladder mucosal and muscle layers were increased after SCI in a time-dependent manner. The liposome-NGF antisense treatment significantly reduced the NGF protein overexpression in the mucosal layer of SCI rat bladder and reduced ΔMAP and ΔMHR elicited by bladder distention. CONCLUSIONS: These results indicate that the duration of the post-SCI recovery period affects the severity of AD induced by bladder distention as well as the level of bladder NGF protein, and that local suppression of NGF expression in the bladder reduces SCI-induced AD. Thus, Intravesical application of liposome-NGF antisense conjugates can be a new effective therapy for bladder distention-induced AD after SCI.
[Mh] Termos MeSH primário: Disreflexia Autonômica/tratamento farmacológico
Lipossomos/uso terapêutico
Fator de Crescimento Neural/metabolismo
Oligodesoxirribonucleotídeos Antissenso/uso terapêutico
Bexiga Urinária/metabolismo
[Mh] Termos MeSH secundário: Análise de Variância
Animais
Disreflexia Autonômica/etiologia
Pressão Sanguínea/efeitos dos fármacos
Pressão Sanguínea/fisiologia
Modelos Animais de Doenças
Feminino
Frequência Cardíaca/efeitos dos fármacos
Frequência Cardíaca/fisiologia
Fator de Crescimento Neural/antagonistas & inibidores
Fator de Crescimento Neural/genética
Oligodesoxirribonucleotídeos Antissenso/farmacologia
Ratos
Ratos Sprague-Dawley
Traumatismos da Medula Espinal/complicações
Fatores de Tempo
Bexiga Urinária/efeitos dos fármacos
Bexiga Urinária/inervação
Urodinâmica/efeitos dos fármacos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Liposomes); 0 (Oligodeoxyribonucleotides, Antisense); 9061-61-4 (Nerve Growth Factor)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170824
[Lr] Data última revisão:
170824
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170209
[St] Status:MEDLINE


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[PMID]:28115072
[Au] Autor:Stillman MD; Barber J; Burns S; Williams S; Hoffman JM
[Ad] Endereço:Department of Rehabilitation Medicine, University of Washington School of Medicine, Seattle, WA; Department of Internal Medicine, University of Washington School of Medicine, Seattle, WA. Electronic address: Michael.stillman1972@gmail.com.
[Ti] Título:Complications of Spinal Cord Injury Over the First Year After Discharge From Inpatient Rehabilitation.
[So] Source:Arch Phys Med Rehabil;98(9):1800-1805, 2017 Sep.
[Is] ISSN:1532-821X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: To describe the prevalence and cumulative incidence of secondary complications of spinal cord injury (SCI) in the first year after discharge from inpatient rehabilitation (IR); and to evaluate potential associations between risk of complications and sociodemographic and injury-specific factors. DESIGN: Secondary analysis of data collected for a single-site, single-blind, randomized controlled trial comparing telephone follow-up with usual care. SETTING: Inpatient rehabilitation units. PARTICIPANTS: Adults ages ≥18 years (N=169) within 1 year of discharge from IR after SCI. INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: Self-report of 10 secondary complications of SCI. RESULTS: Participants experienced a mean of 4.7 complications over 12 months. The most frequently reported complications were urinary tract infection (UTI), autonomic dysreflexia (AD), and pressure ulcers, with cumulative incidences of 62%, 43%, and 41%, respectively. Bone and soft tissue injuries (cumulative incidence, 35%) and bowel problems, including impaction or severe constipation (cumulative incidence, 33%), were also common. Cumulative incidences of AD, decubitus ulcers, UTI, and problems with bladder were greater in participants with higher level and more complete injuries, and some recurrent complications were common. Age at injury and impairment level significantly affected rates of complications, and subjects developed an average of 2.33 distinct complications during the study period. CONCLUSIONS: People with SCI are at high risk for a number of secondary complications over the first year after discharge from IR. Although these data offer some insight into who with SCI is at highest risk for first time and recurrent complications, further study is needed to refine this understanding and to develop effective educational and prevention strategies.
[Mh] Termos MeSH primário: Pacientes Internados/estatística & dados numéricos
Alta do Paciente/estatística & dados numéricos
Avaliação de Resultados da Assistência ao Paciente
Centros de Reabilitação/estatística & dados numéricos
Traumatismos da Medula Espinal/complicações
[Mh] Termos MeSH secundário: Adulto
Fatores Etários
Disreflexia Autonômica/epidemiologia
Disreflexia Autonômica/etiologia
Feminino
Seguimentos
Seres Humanos
Incidência
Masculino
Meia-Idade
Lesão por Pressão/epidemiologia
Lesão por Pressão/etiologia
Prevalência
Fatores de Risco
Método Simples-Cego
Traumatismos da Medula Espinal/reabilitação
Fatores de Tempo
Infecções Urinárias/epidemiologia
Infecções Urinárias/etiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170921
[Lr] Data última revisão:
170921
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170125
[St] Status:MEDLINE


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[PMID]:27618973
[Au] Autor:Martin Ginis KA; Tomasone JR; Welsford M; Ethans K; Sinden AR; Longeway M; Krassioukov A
[Ad] Endereço:Department of Kinesiology, McMaster University, Hamilton, ON, Canada.
[Ti] Título:Online training improves paramedics' knowledge of autonomic dysreflexia management guidelines.
[So] Source:Spinal Cord;55(2):216-222, 2017 Feb.
[Is] ISSN:1476-5624
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:STUDY DESIGN: Single-group pre-/post-test with 3- and 6-month follow-ups. OBJECTIVES: To test the effects of the 'ABCs of AD' educational module on immediate and longer-term changes in paramedics' knowledge and beliefs about using the autonomic dysreflexia clinical practice guidelines (AD-CPGs). SETTING: Canada. METHODS: A total of 119 paramedics completed an AD knowledge test and measures of attitudes, perceived control, self-efficacy, social pressure from patients and health-care professionals, and intentions to use the AD-CPGs before and 1 week, 3 months and 6 months after viewing 'ABCs of AD'. RESULTS: There were significant improvements in AD knowledge, attitudes and social pressure from patients to use the AD-CPGs from baseline to 1 week, 3 months and 6 months post viewing (all P<0.001). Self-efficacy and intentions increased 1 week post viewing (P<0.001), but returned to baseline levels at 3 and 6 months (P>0.05). There was no change in perceived control or social pressure from health-care professionals. AD knowledge and beliefs explained 50-61% of the variance in intentions to use the AD-CPGs. Attitudes, social pressure from patients and perceived behavioural control were significant unique predictors of intentions at all time points (P<0.05); AD knowledge was a significant predictor at 6 months only (P=0.048). No other predictors were significant. CONCLUSION: 'ABCs of AD' has immediate and sustained effects on paramedics' knowledge of attitudes toward and perceived pressure from patients to use the AD-CPGs. Updates to paramedic patient care guidelines and standards are needed to increase paramedics' perceived control and self-efficacy to implement the guidelines, and their intentions to use the AD-CPGs. SPONSORSHIP: Canadian Institutes of Health Research (2011-CIHR- 260877).
[Mh] Termos MeSH primário: Pessoal Técnico de Saúde/educação
Disreflexia Autonômica/terapia
Gerenciamento Clínico
Conhecimentos, Atitudes e Prática em Saúde
Internet
Guias de Prática Clínica como Assunto
[Mh] Termos MeSH secundário: Adulto
Pessoal Técnico de Saúde/normas
Disreflexia Autonômica/diagnóstico
Disreflexia Autonômica/epidemiologia
Feminino
Seguimentos
Seres Humanos
Internet/normas
Masculino
Meia-Idade
Projetos Piloto
Guias de Prática Clínica como Assunto/normas
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160914
[St] Status:MEDLINE
[do] DOI:10.1038/sc.2016.116


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[PMID]:27481090
[Au] Autor:Liu N; Zhou MW; Biering-Sørensen F; Krassioukov AV
[Ad] Endereço:Department of Rehabilitation Medicine, Peking University Third Hospital, Beijing, China.
[Ti] Título:Cardiovascular response during urodynamics in individuals with spinal cord injury.
[So] Source:Spinal Cord;55(3):279-284, 2017 Mar.
[Is] ISSN:1476-5624
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:STUDY DESIGN: Retrospective chart review. OBJECTIVES: To establish the frequency and severity of autonomic dysreflexia (AD) during urodynamics among individuals with chronic spinal cord injury (SCI) and to investigate the possible effect of the number of years since SCI on the severity of AD. SETTING: SCI outpatient clinic. METHODS: A retrospective chart review was undertaken of individuals with SCI who were seen at an outpatient clinic and could potentially develop an episode of AD (T6 and above). Data regarding age, gender, urodynamic examination, lower urinary tract function, cardiovascular parameters and SCI were collected. In addition, information on signs and symptoms of AD were retrieved. RESULTS: A total of 76 individuals with SCI were examined with blood pressure (BP) monitoring. The majority had cervical SCI (79%). The mean age was 47.8±13.9 years. The median duration after SCI was 51.5 months. During urodynamics, a total of 48 (63.2%) individuals showed an increase in systolic BP>20 mm Hg, meeting the criteria for AD. Indicators for higher incidences of AD were cervical SCI, being >2 years after SCI, the presence of detrusor sphincter dyssynergia (DSD) and low bladder compliance. AD was more severe in individuals with complete (American Spinal Cord Association (ASIA) impairment scale (AIS) A) injuries, worse with greater time after SCI. CONCLUSION: Individuals with cervical SCI, DSD, poor bladder compliance or >2 years after SCI were associated with a higher possibility of developing AD during urodynamics. Furthermore, AD was more severe in complete (AIS A) individuals and was exacerbated with time after injury.
[Mh] Termos MeSH primário: Disreflexia Autonômica/fisiopatologia
Pressão Sanguínea/fisiologia
Frequência Cardíaca/fisiologia
Traumatismos da Medula Espinal/fisiopatologia
Urodinâmica/fisiologia
[Mh] Termos MeSH secundário: Adulto
Idoso
Idoso de 80 Anos ou mais
Instituições de Assistência Ambulatorial
Disreflexia Autonômica/epidemiologia
Disreflexia Autonômica/etiologia
Determinação da Pressão Arterial
Vértebras Cervicais
Feminino
Seres Humanos
Incidência
Masculino
Meia-Idade
Pacientes Ambulatoriais
Estudos Retrospectivos
Índice de Gravidade de Doença
Traumatismos da Medula Espinal/complicações
Traumatismos da Medula Espinal/epidemiologia
Vértebras Torácicas
Doenças da Bexiga Urinária/epidemiologia
Doenças da Bexiga Urinária/etiologia
Doenças da Bexiga Urinária/fisiopatologia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170314
[Lr] Data última revisão:
170314
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160803
[St] Status:MEDLINE
[do] DOI:10.1038/sc.2016.110


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[PMID]:27698067
[Au] Autor:West CR; Squair JW; McCracken L; Currie KD; Somvanshi R; Yuen V; Phillips AA; Kumar U; McNeill JH; Krassioukov AV
[Ad] Endereço:From the International Collaboration on Repair Discoveries (C.R.W., J.W.S., L.M., K.D.C., A.A.P., A.V.K), School of Kinesiology, Faculty of Education (C.R.W., L.M.), MD-PhD Training Program, Faculty of Medicine (J.W.S.), Faculty of Pharmaceutical Sciences (R.S., V.Y., U.K., J.H.M.), and Faculty of M
[Ti] Título:Cardiac Consequences of Autonomic Dysreflexia in Spinal Cord Injury.
[So] Source:Hypertension;68(5):1281-1289, 2016 Nov.
[Is] ISSN:1524-4563
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Autonomic dysreflexia (AD), which describes episodic hypertension, is highly prevalent in people with spinal cord injury (SCI). In non-SCI, primary hypertension depresses cardiac contractile reserve via ß-adrenergic mechanisms. In this study, we investigated whether AD contributes to the impairment in cardiac contractile function that accompanies SCI. We induced SCI in rodents and stratified them into sham, SCI, or SCI plus repetitive induction of AD. At 6-week post-SCI, we assessed cardiac function using in vivo (speckle-tracking echocardiography), ex vivo (working heart), and molecular approaches (Western blot). We also provide unique translational insight by comparing the relationship between the number of daily AD events and cardiac function in 14 individuals with cervical SCI. We found SCI and SCI plus repetitive induction of AD exhibited a reduction in left ventricular dimensions at 6-week post-SCI versus preinjury (P<0.049). Compared with sham, SCI exhibited a reduction in peak radial strain along with a down and rightward shift in the Starling curve (P<0.037), both of which were further depressed in SCI plus repetitive induction of AD (P<0.042). In response to ß-adrenergic stimulation, SCI plus repetitive induction of AD exhibited an attenuated increase in contractile indices (P<0.001), despite no differences in ß-receptor expression within the left ventricle. Our clinical data confirm our experimental findings by demonstrating significant associations between the number of daily AD events and markers of systolic and diastolic function along with left ventricular mechanics. Here, we provide the first evidence from a translational perspective that AD exerts insidious effects on cardiac function in rodents and humans with SCI.
[Mh] Termos MeSH primário: Disreflexia Autonômica/complicações
Hipertensão/fisiopatologia
Contração Miocárdica/fisiologia
Traumatismos da Medula Espinal/complicações
Função Ventricular Esquerda/fisiologia
[Mh] Termos MeSH secundário: Animais
Disreflexia Autonômica/fisiopatologia
Monitorização Ambulatorial da Pressão Arterial
Doenças Cardiovasculares/etiologia
Doenças Cardiovasculares/fisiopatologia
Modelos Animais de Doenças
Hipertensão Essencial
Seres Humanos
Hipertensão/etiologia
Masculino
Análise Multivariada
Distribuição Aleatória
Ratos
Ratos Wistar
Valores de Referência
Análise de Regressão
Medição de Risco
Amostragem
Traumatismos da Medula Espinal/fisiopatologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161005
[St] Status:MEDLINE


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[PMID]:27574816
[Au] Autor:Cloutier F; Kalincik T; Lauschke J; Tuxworth G; Cavanagh B; Meedeniya A; Mackay-Sim A; Carrive P; Waite P
[Ad] Endereço:School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia. Electronic address: fra.cloutier@gmail.com.
[Ti] Título:Olfactory ensheathing cells but not fibroblasts reduce the duration of autonomic dysreflexia in spinal cord injured rats.
[So] Source:Auton Neurosci;201:17-23, 2016 Dec.
[Is] ISSN:1872-7484
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Autonomic dysreflexia is a common complication after high level spinal cord injury and can be life-threatening. We have previously shown that the acute transplantation of olfactory ensheathing cells into the lesion site of rats transected at the fourth thoracic spinal cord level reduced autonomic dysreflexia up to 8weeks after spinal cord injury. This beneficial effect was correlated with changes in the morphology of sympathetic preganglionic neurons despite the olfactory cells surviving no longer than 3weeks. Thus the transitory presence of olfactory ensheathing cells at the injury site initiated long-term functional as well as morphological changes in the sympathetic preganglionic neurons. The primary aim of the present study was to evaluate whether olfactory ensheathing cells survive after transplantation within the parenchyma close to sympathetic preganglionic neurons and whether, in this position, they still reduce the duration of autonomic dysreflexia and modulate sympathetic preganglionic neuron morphology. The second aim was to quantify the density of synapses on the somata of sympathetic preganglionic neurons with the hypothesis that the reduction of autonomic dysreflexia requires synaptic changes. As a third aim, we evaluated the cell type-specificity of olfactory ensheathing cells by comparing their effects with a control group transplanted with fibroblasts. Animals transplanted with OECs had a faster recovery from hypertension induced by colorectal distension at 6 and 7weeks but not at 8weeks after T4 spinal cord transection. Olfactory ensheathing cells survived for at least 8weeks and were observed adjacent to sympathetic preganglionic neurons whose overall number of primary dendrites was reduced and the synaptic density on the somata increased, both caudal to the lesion site. Our results showed a long term cell type-specific effects of olfactory ensheathing cells on sympathetic preganglionic neurons morphology and on the synaptic density on their somata, and a transient cell type-specific reduction of autonomic dysreflexia.
[Mh] Termos MeSH primário: Disreflexia Autonômica/terapia
Fibroblastos/transplante
Neuroglia/transplante
[Mh] Termos MeSH secundário: Animais
Disreflexia Autonômica/patologia
Disreflexia Autonômica/fisiopatologia
Pressão Sanguínea/fisiologia
Sobrevivência Celular
Modelos Animais de Doenças
Fibroblastos/patologia
Fibroblastos/fisiologia
Frequência Cardíaca/fisiologia
Masculino
Neuroglia/patologia
Neuroglia/fisiologia
Neurônios/patologia
Neurônios/fisiologia
Mucosa Olfatória/patologia
Mucosa Olfatória/fisiologia
Mucosa Olfatória/transplante
Ratos Wistar
Transplante de Pele
Sistema Nervoso Simpático/patologia
Sistema Nervoso Simpático/fisiopatologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170822
[Lr] Data última revisão:
170822
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160831
[St] Status:MEDLINE


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[PMID]:27544957
[Au] Autor:Rodger S
[Ti] Título:Care of spinal cord injury in non-specialist settings.
[So] Source:Nurs Times;112(26):12-5, 2016 Jun 29-Jul 5.
[Is] ISSN:0954-7762
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Patient with spinal cord injuries have individualised care routines to help prevent complications. Disruption to these routines following admission to non-specialist settings can have long-term consequences. This article focuses on the key long-term problems of pressure ulcers, bladder and bowel dysfunction, and autonomic dysreflexia. Nurses working on general wards need to consider how to manage these problems when caring for patients with spinal cord injury.
[Mh] Termos MeSH primário: Disreflexia Autonômica/enfermagem
Incontinência Fecal/prevenção & controle
Lesão por Pressão/prevenção & controle
Traumatismos da Medula Espinal/enfermagem
Bexiga Urinaria Neurogênica/enfermagem
[Mh] Termos MeSH secundário: Disreflexia Autonômica/etiologia
Defecação
Incontinência Fecal/etiologia
Incontinência Fecal/enfermagem
Hospitalização
Seres Humanos
Educação de Pacientes como Assunto
Lesão por Pressão/enfermagem
Encaminhamento e Consulta
Higiene da Pele/enfermagem
Especialização
Traumatismos da Medula Espinal/complicações
Bexiga Urinaria Neurogênica/etiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1609
[Cu] Atualização por classe:160822
[Lr] Data última revisão:
160822
[Sb] Subgrupo de revista:N
[Da] Data de entrada para processamento:160823
[St] Status:MEDLINE


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[PMID]:27500446
[Au] Autor:Popok D; West C; Frias B; Krassioukov AV
[Ad] Endereço:International Collaboration on Repair Discoveries (ICORD), Faculty of Medicine, University of British Columbia; davidpopok@gmail.com.
[Ti] Título:Development of an Algorithm to Perform a Comprehensive Study of Autonomic Dysreflexia in Animals with High Spinal Cord Injury Using a Telemetry Device.
[So] Source:J Vis Exp;(113), 2016 Jul 29.
[Is] ISSN:1940-087X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Spinal cord injury (SCI) is a debilitating neurological condition characterized by somatic and autonomic dysfunctions. In particular, SCI above the mid-thoracic level can lead to a potentially life-threatening hypertensive condition called autonomic dysreflexia (AD) that is often triggered by noxious or non-noxious somatic or visceral stimuli below the level of injury. One of the most common triggers of AD is the distension of pelvic viscera, such as during bladder and bowel distension or evacuation. This protocol presents a novel pattern recognition algorithm developed for a JAVA platform software to study the fluctuations of cardiovascular parameters as well as the number, severity and duration of spontaneously occurring AD events. The software is able to apply a pattern recognition algorithm on hemodynamic data such as systolic blood pressure (SBP) and heart rate (HR) extracted from telemetry recordings of conscious and unrestrained animals before and after thoracic (T3) complete transection. With this software, hemodynamic parameters and episodes of AD are able to be detected and analyzed with minimal experimenter bias.
[Mh] Termos MeSH primário: Traumatismos da Medula Espinal
[Mh] Termos MeSH secundário: Algoritmos
Animais
Disreflexia Autonômica
Pressão Sanguínea
Medula Espinal
Telemetria
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170811
[Lr] Data última revisão:
170811
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160809
[St] Status:MEDLINE
[do] DOI:10.3791/52809


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Fotocópia
[PMID]:27447129
[Au] Autor:Singhal R; Anthony A; Xiong X; Acland R
[Ad] Endereço:Senior Lecturer University of Otago and Clinical Director, Burwood Spinal Unit, Christchurch, New Zealand. Raj.Singhal@cdhb.health.nz.
[Ti] Título:Ageing in spinal cord injuries.
[So] Source:N Z Med J;129(1438):8-11, 2016 Jul 15.
[Is] ISSN:1175-8716
[Cp] País de publicação:New Zealand
[La] Idioma:eng
[Mh] Termos MeSH primário: Envelhecimento/fisiologia
Traumatismos da Medula Espinal/fisiopatologia
[Mh] Termos MeSH secundário: Disreflexia Autonômica/fisiopatologia
Transtornos Traumáticos Cumulativos/fisiopatologia
Diabetes Mellitus/fisiopatologia
Seres Humanos
Hiponatremia/fisiopatologia
Hipotensão Ortostática/fisiopatologia
Síndrome de Secreção Inadequada de HAD/fisiopatologia
Infertilidade Masculina/fisiopatologia
Masculino
Megacolo/fisiopatologia
Síndrome Metabólica/fisiopatologia
Neuralgia/fisiopatologia
Lesão por Pressão/fisiopatologia
Qualidade de Vida
Escoliose/fisiopatologia
Síndromes da Apneia do Sono/fisiopatologia
Espasmo/fisiopatologia
Extremidade Superior/fisiopatologia
Bexiga Urinaria Neurogênica/fisiopatologia
[Pt] Tipo de publicação:EDITORIAL
[Em] Mês de entrada:1704
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160723
[St] Status:MEDLINE



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