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[PMID]:29467153
[Au] Autor:Le Couteur DG; Bateman B; Brayne C
[Ad] Endereço:Centre for Education and Research on Ageing, Concord Hospital and University of Sydney, Sydney, Australia.
[Ti] Título:Idalopirdine: another disappointment for people with dementia.
[So] Source:BMJ;360:k753, 2018 02 21.
[Is] ISSN:1756-1833
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Benzilaminas/uso terapêutico
Demência/tratamento farmacológico
Indóis/uso terapêutico
Antagonistas da Serotonina/uso terapêutico
[Mh] Termos MeSH secundário: Ensaios Clínicos como Assunto
Seres Humanos
Falha de Tratamento
[Pt] Tipo de publicação:EDITORIAL
[Nm] Nome de substância:
0 ((2-(6-fluoro-1H-indol-3-yl)-ethyl)-(3-(2,2,3,3-tetrafluoropropoxy)benzyl)amine); 0 (Benzylamines); 0 (Indoles); 0 (Serotonin Antagonists)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180223
[St] Status:MEDLINE
[do] DOI:10.1136/bmj.k753


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[PMID]:29258980
[Au] Autor:Boots LM; de Vugt ME; Smeets CM; Kempen GI; Verhey FR
[Ad] Endereço:Department of Psychiatry and Neuropsychology, Alzheimer Center Limburg, School for Mental Health and Neurosciences, Maastricht University Medical Center+, Maastricht, Netherlands.
[Ti] Título:Implementation of the Blended Care Self-Management Program for Caregivers of People With Early-Stage Dementia (Partner in Balance): Process Evaluation of a Randomized Controlled Trial.
[So] Source:J Med Internet Res;19(12):e423, 2017 Dec 19.
[Is] ISSN:1438-8871
[Cp] País de publicação:Canada
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Caring for a family member with dementia puts caregivers at risk of overburdening. Electronic health (eHealth) support for caregivers offers an opportunity for accessible tailored interventions. The blended care self-management program "Partner in Balance" (PiB) for early-stage dementia caregivers was executed in Dutch dementia care organizations. The program combines face-to-face coaching with tailored Web-based modules. Next to an evaluation of program effectiveness, an evaluation of sampling and intervention quality is essential for the generalizability and interpretation of results. OBJECTIVE: The aim of this study was to describe the process evaluation from the perspective of both family caregivers (participants) and professionals delivering the intervention (coaches) to determine internal and external validity before the effect analysis and aid future implementation. METHODS: Implementation, sampling, and intervention quality were evaluated with quantitative and qualitative data from logistical research data, coach questionnaires (n=13), and interviews with coaches (n=10) and participants (n=49). Goal attainment scaling was used to measure treatment-induced change. Analyses were performed with descriptive statistics and deductive content analysis. RESULTS: The participation rate of eligible caregivers was 51.9% (80/154). Recruitment barriers were lack of computer and lack of need for support. Young age and employment were considered recruitment facilitators. All coaches attended training and supervision in blended care self-management. Deviations from the structured protocol were reported on intervention time, structure, and feedback. Coaches described an intensified relationship with the caregiver post intervention. Caregivers appreciated the tailored content and positive feedback. The blended structure increased their openness. The discussion forum was appreciated less. Overall, personal goals were attained after the program (T>50). Implementation barriers included lack of financing, time, and deviating target population. CONCLUSIONS: Participants and coaches were satisfied with the intervention, but adapting the content to specific subgroups, for example, younger caregivers, was recommended. Implementation of the program requires more awareness of the benefits of blended care self-management programs and training in tailored self-management skills. TRIAL REGISTRATION: Dutch Trial Register (NTR): NTR4748; http://www.trialregister.nl (Archived by WebCite at http://www.webcitation.org/6vSb2t9Mg).
[Mh] Termos MeSH primário: Demência/terapia
Autogestão/métodos
[Mh] Termos MeSH secundário: Idoso
Cuidadores
Feminino
Seres Humanos
Inquéritos e Questionários
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171221
[St] Status:MEDLINE
[do] DOI:10.2196/jmir.7666


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[PMID]:29240489
[Au] Autor:Mendes A
[Ad] Endereço:Freelance Journalist, specialising in health, psychology and nursing.
[Ti] Título:Recognising and assessing care needs in patients with dementia: the three Ds.
[So] Source:Br J Nurs;26(22):1260-1261, 2017 Dec 14.
[Is] ISSN:0966-0461
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Aysha Mendes, Freelance Journalist, specialising in health, psychology and nursing, aysha.freelance@gmail.com.
[Mh] Termos MeSH primário: Demência/terapia
Determinação de Necessidades de Cuidados de Saúde
[Mh] Termos MeSH secundário: Demência/diagnóstico
Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180306
[Lr] Data última revisão:
180306
[Sb] Subgrupo de revista:N
[Da] Data de entrada para processamento:171215
[St] Status:MEDLINE
[do] DOI:10.12968/bjon.2017.26.22.1260


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[PMID]:28462758
[Au] Autor:Haynes BI; Bauermeister S; Bunce D
[Ad] Endereço:1School of Psychology,University of Leeds,Leeds,United Kingdom.
[Ti] Título:A Systematic Review of Longitudinal Associations Between Reaction Time Intraindividual Variability and Age-Related Cognitive Decline or Impairment, Dementia, and Mortality.
[So] Source:J Int Neuropsychol Soc;23(5):431-445, 2017 May.
[Is] ISSN:1469-7661
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: Intraindividual variability (IIV) in reaction time refers to the trial-to-trial fluctuations in responding across a given cognitive task. Cross-sectional research suggests that IIV increases with normal and neuropathological ageing and it may serve as a marker of neurobiological integrity. This raises the possibility that IIV may also predict future cognitive decline and, indeed, neuropathology. Therefore, we conducted a systematic review to address these issues. METHODS: A search of electronic databases Embase, Medline, PsycINFO, and Web of Science was completed on May 17, 2016 that identified longitudinal investigations of IIV in middle-aged or older adults. RESULTS: A total of 688 studies were initially identified of which 22 met the inclusion criteria. Nine included longitudinal IIV measures and 17 predicted subsequent outcome (cognitive decline or impairment, dementia, mortality) from baseline IIV. The results suggested IIV increased over time, particularly in participants aged over 75 years. Greater baseline IIV was consistently associated with increased risk of adverse outcomes including cognitive decline or impairment, and mortality. CONCLUSIONS: Increased IIV over time is associated with normal ageing. However, further increases in IIV over and above those found in normal ageing may be a risk factor for future cognitive impairment or mortality. Measures of IIV may, therefore, have considerable potential as a supplement to existing clinical assessment to aid identification of individuals at risk of adverse outcomes such as dementia or death. (JINS, 2017, 23, 431-445).
[Mh] Termos MeSH primário: Envelhecimento
Disfunção Cognitiva
Demência
Individualidade
Tempo de Reação/fisiologia
[Mh] Termos MeSH secundário: Disfunção Cognitiva/mortalidade
Disfunção Cognitiva/patologia
Disfunção Cognitiva/fisiopatologia
Bases de Dados Bibliográficas/estatística & dados numéricos
Demência/mortalidade
Demência/patologia
Demência/fisiopatologia
Seres Humanos
Estudos Longitudinais
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180306
[Lr] Data última revisão:
180306
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170503
[St] Status:MEDLINE
[do] DOI:10.1017/S1355617717000236


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[PMID]:28743253
[Au] Autor:Greenwood N; Smith R; Akhtar F; Richardson A
[Ad] Endereço:Faculty of Health, Social Care and Education, Kingston University and St George's, University of London, 6th Floor Hunter Wing, St George's, University of London, Cranmer Terrace, London, SW17 0RE, UK. Nan.Greenwood1@gmail.com.
[Ti] Título:A qualitative study of carers' experiences of dementia cafés: a place to feel supported and be yourself.
[So] Source:BMC Geriatr;17(1):164, 2017 Jul 25.
[Is] ISSN:1471-2318
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Unpaid, informal carers or caregivers play an important role in supporting people living with dementia but the role can be challenging and carers themselves may benefit from support. Alzheimer's, dementia or memory cafés are one such form of support . These cafés are usually provided in the voluntary sector and are a place where people with dementia and those supporting them, usually family carers, can meet with others in similar situations. METHODS: Using semi-structured interviews, this qualitative study explored the experiences of 11 carers from five dementia cafés in and around London, England. RESULTS: Thematic analysis resulted in the identification of four key themes. Cafés provide a relaxed, welcoming atmosphere where carers can go where they feel supported and accepted. Café attendance often brought a sense of normality to these carers' lives. Carers and those they care for look forward to going and often enjoy both the activities provided and socialising with others. Other highlighted benefits included peer support from other carers, information provision and support from the volunteer café coordinators. Despite diversity in how the cafés were run and in the activities offered, there were many reported similarities amongst carers in the value ascribed to attending the cafés. CONCLUSIONS: Dementia cafés appear to be a valuable, perhaps unique form of support for carers giving them brief respite from their caring role. Future research incorporating mixed methods is needed to understand the perspectives of those living with dementia.
[Mh] Termos MeSH primário: Cuidadores/psicologia
Cuidadores/normas
Demência/psicologia
Demência/terapia
Pesquisa Qualitativa
Apoio Social
[Mh] Termos MeSH secundário: Adulto
Idoso
Idoso de 80 Anos ou mais
Aconselhamento/métodos
Inglaterra/epidemiologia
Feminino
Seres Humanos
Londres/epidemiologia
Masculino
Meia-Idade
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180305
[Lr] Data última revisão:
180305
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170727
[St] Status:MEDLINE
[do] DOI:10.1186/s12877-017-0559-4


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[PMID]:29361626
[Au] Autor:Asai M; Tanaka H; Goto Y; Yamada T; Yuasa N; Takeuchi E; Miyake H; Nagai H; Yoshioka Y; Okuno M; Kawai N; Minami T; Nagao T; Maeda S; Mouri K; Fukata K; Mizuno H; Iwase T; Miyata K
[Ad] Endereço:Dept. of Surgery, Japanese Red Cross Nagoya Daiichi Hospital.
[Ti] Título:[Secondary Dementia Due to Leptomeningeal Metastasis of Breast Cancer Improved by Whole Brain Radiation].
[So] Source:Gan To Kagaku Ryoho;44(13):2101-2103, 2017 Dec.
[Is] ISSN:0385-0684
[Cp] País de publicação:Japan
[La] Idioma:jpn
[Ab] Resumo:A 62-year-old woman received chemotherapy for breast cancer with bone metastasis and malignant pleural and pericardial effusion. She was examined by imaging for progressive cognitive impairment and headache. Enhanced MRI findings showed multiple solid tumors on brain surface, and brain perfusion scintigraphy showed blood flow decrease in both parietal lobes. She was diagnosed with secondary dementia due to leptomeningeal metastases of breast cancer, and whole brain external irradiation was performed(30 Gy/15 Fr). After treatment, multiple tumors were decreased in size and her cognitive impair- ment was improved.
[Mh] Termos MeSH primário: Neoplasias Encefálicas/radioterapia
Neoplasias da Mama/patologia
Demência/etiologia
Neoplasias Meníngeas/radioterapia
[Mh] Termos MeSH secundário: Neoplasias Encefálicas/diagnóstico por imagem
Neoplasias Encefálicas/secundário
Feminino
Seres Humanos
Imagem por Ressonância Magnética
Neoplasias Meníngeas/diagnóstico por imagem
Neoplasias Meníngeas/secundário
Meia-Idade
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180302
[Lr] Data última revisão:
180302
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180124
[St] Status:MEDLINE


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[PMID]:29406043
[Au] Autor:Tzeng NS; Chung CH; Liu FC; Chiu YH; Chang HA; Yeh CB; Huang SY; Lu RB; Yeh HW; Kao YC; Chiang WS; Tsao CH; Wu YF; Chou YC; Lin FH; Chien WC
[Ad] Endereço:Department of Psychiatry, Tri-Service General Hospital, School of Medicine, National Defense Medical Center, Taipei, Taiwan, ROC; Student Counseling Center, National Defense Medical Center, Taipei, Taiwan, ROC.
[Ti] Título:Fibromyalgia and Risk of Dementia-A Nationwide, Population-Based, Cohort Study.
[So] Source:Am J Med Sci;355(2):153-161, 2018 02.
[Is] ISSN:1538-2990
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Fibromyalgia is a syndrome of chronic pain and other symptoms and is associated with patient discomfort and other diseases. This nationwide matched-cohort population-based study aimed to investigate the association between fibromyalgia and the risk of developing dementia, and to clarify the association between fibromyalgia and dementia. MATERIALS AND METHODS: A total of 41,612 patients of age ≥50 years with newly diagnosed fibromyalgia between January 1, and December 31, 2000 were selected from the National Health Insurance Research Database of Taiwan, along with 124,836 controls matched for sex and age. After adjusting for any confounding factors, Fine and Gray competing risk analysis was used to compare the risk of developing dementia during the 10 years of follow-up. RESULTS: Of the study subjects, 1,704 from 41,612 fibromyalgia patients (21.23 per 1,000 person-years) developed dementia when compared to 4,419 from 124,836 controls (18.94 per 1,000 person-years). Fine and Gray competing risk analysis revealed that the study subjects were more likely to develop dementia (hazard ratio: 2.29, 95% CI: 2.16-2.42; P < 0.001). After adjusting for sex, age, monthly income, urbanization level, geographic region of residence and comorbidities the hazard ratio was 2.77 (95% CI: 2.61-2.95, P < 0.001). Fibromyalgia was associated with increased risk of all types of dementia in this study. CONCLUSIONS: The study subjects with fibromyalgia had a 2.77-fold risk of dementia in comparison to the control group. Therefore, further studies are needed to elucidate the underlying mechanisms of the association between fibromyalgia and the risk of dementia.
[Mh] Termos MeSH primário: Bases de Dados Factuais
Demência/epidemiologia
Demência/etiologia
Fibromialgia/complicações
Fibromialgia/epidemiologia
[Mh] Termos MeSH secundário: Fatores Etários
Idoso
Idoso de 80 Anos ou mais
Demência/fisiopatologia
Feminino
Fibromialgia/fisiopatologia
Seguimentos
Seres Humanos
Masculino
Meia-Idade
Fatores de Risco
Fatores Sexuais
Fatores Socioeconômicos
Taiwan/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180301
[Lr] Data última revisão:
180301
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180207
[St] Status:MEDLINE


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[PMID]:29258633
[Au] Autor:Batchelor P
[Ti] Título:Dementia-Friendly Dentistry: Why Dementia Guidelines?
[So] Source:Prim Dent J;6(4):10-11, 2017 Dec 01.
[Is] ISSN:2050-1684
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:FGDP(UK) recently launched its dementia-friendly dentistry: good practice guidelines publication, which members will have received free-of-charge. Vice Dean and editor of the guidelines, Paul Batchelor, explains why the publication is necessary and why all practitioners should make the effort to incorporate these recommendations into their practice.
[Mh] Termos MeSH primário: Demência
Assistência Odontológica para Doentes Crônicos
Guias de Prática Clínica como Assunto
[Mh] Termos MeSH secundário: Seres Humanos
Garantia da Qualidade dos Cuidados de Saúde
Odontologia Estatal
Reino Unido
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180227
[Lr] Data última revisão:
180227
[Sb] Subgrupo de revista:D
[Da] Data de entrada para processamento:171221
[St] Status:MEDLINE
[do] DOI:10.1308/205016817822230229


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[PMID]:29206977
[Au] Autor:Brandão D; Ribeiro O; Martín I
[Ad] Endereço:Research and Education Unit on Ageing (UNIFAI/ICBAS-UP), Institute of Biomedical Sciences Abel Salazar, Department of Behavioral Sciences, University of Porto, Porto.
[Ti] Título:Underuse and Unawareness of Residential Respite Care Services in Dementia Caregiving: Constraining the Need for Relief.
[So] Source:Health Soc Work;41(4):254-262, 2016 Nov 20.
[Is] ISSN:0360-7283
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:This article describes an analysis of the use of residential respite care services and the factors that influence the use of such services among informal caregivers of people with dementia. The authors studied a sample of 223 caregivers participating in a community-based intervention project in northern Portugal. Participants provided information on their overall caregiving situation and on their use or willingness to use respite care services. Results showed that fewer than 6 percent of caregivers accessed the services and that although most caregivers were not familiar with these services, they recognized their importance and strongly considered the possibility of using them. Part-time care, lower levels of gratification, higher burden, and the care receiver's attendance of day center supported the willingness to use residential respite services. The limited offer, not knowing about the services, and cultural issues related to the family duties within the caregiving role can explain the low use of these services. Social work professionals have an important role in promoting residential respite care services, and thereby helping to reduce caregiving overload.
[Mh] Termos MeSH primário: Conscientização
Cuidadores/psicologia
Demência/enfermagem
Cuidados Intermitentes/utilização
[Mh] Termos MeSH secundário: Adulto
Idoso
Idoso de 80 Anos ou mais
Estudos Transversais
Feminino
Seres Humanos
Masculino
Meia-Idade
Portugal
Inquéritos e Questionários
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180227
[Lr] Data última revisão:
180227
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171206
[St] Status:MEDLINE
[do] DOI:10.1093/hsw/hlw041


  10 / 42135 MEDLINE  
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[PMID]:29280846
[Au] Autor:Li H; Osborne L
[Ad] Endereço:Hongyan Li is a RN-DNP student at the University of Pittsburgh, Pa. Lisa Osborne is a unit manager at Heritage Place in Pittsburgh, Pa.
[Ti] Título:Pain management for long-term-care residents.
[So] Source:Nursing;48(1):64-67, 2018 Jan.
[Is] ISSN:1538-8689
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Casas de Saúde
Manejo da Dor/enfermagem
Melhoria de Qualidade/organização & administração
[Mh] Termos MeSH secundário: Demência/enfermagem
Metas
Seres Humanos
Assistência de Longa Duração
Pesquisa em Avaliação de Enfermagem
Recursos Humanos de Enfermagem/educação
Medição da Dor/enfermagem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180222
[Lr] Data última revisão:
180222
[Sb] Subgrupo de revista:N
[Da] Data de entrada para processamento:171228
[St] Status:MEDLINE
[do] DOI:10.1097/01.NURSE.0000526906.76239.6e



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