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[PMID]:29489688
[Au] Autor:Akiyama H; Hasegawa Y
[Ti] Título:A trial case of medical treatment for primary headache using telemedicine.
[So] Source:Medicine (Baltimore);97(9):e9891, 2018 Mar.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:RATIONALE: Video-based treatment in telemedicine is a potential alternative to face-to-face treatment. We describe our trial use of telemedicine to treat a patient with primary headache. PATIENT CONCERNS: A 25-year-old woman visited our branch hospital with a chief complaint of recurrent headache. Our branch hospital had no headache specialist, so a headache specialist at our main hospital provided treatment remotely. DIAGNOSES: She was diagnosed with migraine without aura by the headache specialist using telemedicine. INTERVENTIONS: The branch hospital physician and the headache specialist used video conferencing to interview and examine the patient and share cranial magnetic resonance imaging (MRI). Audio and camera angle/zoom could be adjusted during interviews, and high-quality video was continuously displayed at both hospitals simultaneously without lag between audio and video. Temporal/spatial resolution was sufficient for proper neurological evaluation. MRI had sufficient image quality and resolution for detailed interpretation. A prescription for medication was issued by the branch hospital physician and confirmed by the headache specialist. OUTCOMES: Zolmitriptan was effective in treating her migraine. LESSONS: Telemedicine was useful for treating this primary headache patient and can contribute to regional health care. Future challenges in telemedicine include expanding its use to other areas within the purview of general physicians and headache specialists, covering implementation and maintenance costs, providing adequate explanations to patients and family members, ensuring security of video transmissions, maintaining patient medical records, and supervising treatment.
[Mh] Termos MeSH primário: Enxaqueca sem Aura/diagnóstico
Telemedicina/métodos
Videoconferência
[Mh] Termos MeSH secundário: Adulto
Feminino
Seres Humanos
Enxaqueca sem Aura/terapia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180307
[Lr] Data última revisão:
180307
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180301
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000009891


  2 / 675 MEDLINE  
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[PMID]:29357368
[Au] Autor:Yuasa N; Nagata E; Fujii N; Ito M; Tsukamoto H; Takizawa S
[Ad] Endereço:Division of Neurology, Department of Internal Medicine, Isehara Kyodo Hospital, Isehara, Japan.
[Ti] Título:Serum apolipoprotein E may be a novel biomarker of migraine.
[So] Source:PLoS One;13(1):e0190620, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Migraine attacks alter various molecules that might be related to the pathophysiology of migraine, such as serotonin, calcitonin gene-related peptide, and nitric oxide. The underlying pathophysiology of migraine is as yet unclear. We explored key proteins related to the pathogenesis of migraine here. Serum was collected from two patients with migraine with aura (MA) and seven patients with migraine without aura (MO) during attack-free periods and migraine attacks. Samples were analyzed using 2-dimensional gel electrophoresis. Nineteen protein spots were altered between the attack-free versus migraine attack periods. Mass spectrometric analysis was performed to identify the proteins within each of the 19 altered spots. Thirty-six proteins were significantly altered in samples collected during attack-free periods versus migraine attacks. The protein with the statistically most significant MASCOT/Mowse score (268±112) among lipoproteins was apolipoprotein (ApoE). In the MA and MO groups, ApoE protein levels were significantly higher during migraine attack than during the attack-free period (p<0.05). ApoE protein levels were also significantly increased in the MA group during the attack-free period compared to healthy controls and patients with tension type headaches (p<0.01). Migraine alters ApoE levels, especially in MA. ApoE might play an important role in the pathophysiology of migraine, and may act as a diagnostic biomarker of migraine.
[Mh] Termos MeSH primário: Apolipoproteínas E/sangue
Biomarcadores/sangue
Enxaqueca com Aura/sangue
Enxaqueca sem Aura/sangue
[Mh] Termos MeSH secundário: Adulto
Eletroforese em Gel Bidimensional
Ensaio de Imunoadsorção Enzimática
Feminino
Seres Humanos
Meia-Idade
Espectrometria de Massas em Tandem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Apolipoproteins E); 0 (Biomarkers)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180221
[Lr] Data última revisão:
180221
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180123
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0190620


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[PMID]:28747203
[Au] Autor:Shi YJ; Lv J; Han XT; Luo GG
[Ad] Endereço:Department of Neurology, Xi'an Jiaotong University, Xi'an, China.
[Ti] Título:Migraine and percutaneous patent foramen ovale closure: a systematic review and meta-analysis.
[So] Source:BMC Cardiovasc Disord;17(1):203, 2017 07 26.
[Is] ISSN:1471-2261
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The association between patent foramen ovale (PFO) and migraine with aura (MA) is well established. However, the benefits of PFO closure are less certain in patients with migraine without aura (MwoA). METHODS: We systematically searched Pubmed for pertinent clinical studies published from January 2000 to July 2015. The primary end-point was the elimination or significant improvement of migraine symptoms after PFO closure. RESULTS: Upon screening an initial list of 315 publications, we identified eight studies that included 546 patients. Overall, our analysis indicated a significant improvement of migraine in 81% of MA cases compared to only 63% of MwoA cases. The summary odds ratio was 2.5 (95% confidence interval 1.09-5.73), and the benefits of PFO closure were significantly greater for patients with MA compared to patients with MwoA (P = 0.03). CONCLUSIONS: The presence of aura provides a reference standard for the clinical selection of patients with migraine for PFO closure intervention.
[Mh] Termos MeSH primário: Cateterismo Cardíaco
Forame Oval Patente/terapia
Enxaqueca com Aura/prevenção & controle
Enxaqueca sem Aura/prevenção & controle
[Mh] Termos MeSH secundário: Adulto
Distribuição de Qui-Quadrado
Feminino
Forame Oval Patente/complicações
Forame Oval Patente/diagnóstico
Forame Oval Patente/fisiopatologia
Seres Humanos
Masculino
Meia-Idade
Enxaqueca com Aura/diagnóstico
Enxaqueca com Aura/etiologia
Enxaqueca sem Aura/diagnóstico
Enxaqueca sem Aura/etiologia
Razão de Chances
Seleção de Pacientes
Fatores de Risco
Fatores de Tempo
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE; META-ANALYSIS; REVIEW
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180213
[Lr] Data última revisão:
180213
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170728
[St] Status:MEDLINE
[do] DOI:10.1186/s12872-017-0644-9


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[PMID]:29059314
[Au] Autor:Chang MY; Phasukkijwatana N; Garrity S; Pineles SL; Rahimi M; Sarraf D; Johnston M; Charles A; Arnold AC
[Ad] Endereço:Stein Eye Institute, University of California, Los Angeles, California, United States.
[Ti] Título:Foveal and Peripapillary Vascular Decrement in Migraine With Aura Demonstrated by Optical Coherence Tomography Angiography.
[So] Source:Invest Ophthalmol Vis Sci;58(12):5477-5484, 2017 Oct 01.
[Is] ISSN:1552-5783
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Purpose: Migraine, particularly with aura, has been associated with ocular and systemic ischemic complications, but there are limited data on the ocular vasculature in migraine. We used optical coherence tomography angiography (OCTA) to assess perfusion of the macula and optic nerve in migraine patients, with (MA) and without (MO) aura, compared to healthy controls (HC). Methods: We recruited 15 MA (mean age 42 years), 12 MO (mean age 46 years), and 22 HC (mean age 39 years) participants from neurology and neuro-ophthalmology clinics. Participants underwent optical coherence tomography and 3 × 3 mm OCTA of the macula and optic nerve. Foveal avascular zone area was automatically measured using AngioVue software, and vessel density was calculated as blood vessel length divided by scan area (mm-1) after skeletonization of OCTA images. Results: On macular OCTA, MA participants had an enlarged foveal avascular zone area when compared with HC (0.300 ± 0.019 vs. 0.220 ± 0.066 mm2, P = 0.006). In addition, superficial foveal vessel density was decreased in MA participants when compared with MO participants (7.8 ± 0.31 vs. 9.3 ± 0.44, P = 0.04) and HC (7.8 ± 0.31 vs. 9.4 ± 0.21 mm-1, P = 0.002). On optic nerve OCTA, the MA participants had reduced superior peripapillary vessel density when compared with the MO participants (12.0 ± 0.45 vs. 14.0 ± 0.38 mm-1, P = 0.031) and HC (12.0 ± 0.45 vs. 14.1 ± 0.53 mm-1, P = 0.035). There were no significant differences between the MO and HC groups. Conclusions: Migraine with, but not without, aura was associated with foveal and peripapillary vascular decrements, which may possibly mediate increased risk of ocular and systemic vascular complications in these patients. OCTA could potentially be useful as a biomarker for migraine with aura.
[Mh] Termos MeSH primário: Fóvea Central/irrigação sanguínea
Enxaqueca com Aura/fisiopatologia
Enxaqueca sem Aura/fisiopatologia
Disco Óptico/irrigação sanguínea
[Mh] Termos MeSH secundário: Adolescente
Adulto
Angiografia por Tomografia Computadorizada
Feminino
Fóvea Central/diagnóstico por imagem
Voluntários Saudáveis
Seres Humanos
Masculino
Meia-Idade
Disco Óptico/diagnóstico por imagem
Tomografia de Coerência Óptica/métodos
Adulto Jovem
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171029
[Lr] Data última revisão:
171029
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171024
[St] Status:MEDLINE
[do] DOI:10.1167/iovs.17-22477


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[PMID]:28656458
[Au] Autor:Pisanu C; Preisig M; Castelao E; Glaus J; Pistis G; Squassina A; Del Zompo M; Merikangas KR; Waeber G; Vollenweider P; Mwinyi J; Schiöth HB
[Ad] Endereço:Division of Functional Pharmacology, Department of Neuroscience, BMC, University of Uppsala, Husargatan 3, 75124, Uppsala, Sweden.
[Ti] Título:A genetic risk score is differentially associated with migraine with and without aura.
[So] Source:Hum Genet;136(8):999-1008, 2017 08.
[Is] ISSN:1432-1203
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:Although a number of migraine-associated single-nucleotide polymorphisms (SNP) with small effect size have been identified, little is known about the additive impact of these variants on migraine risk, frequency and severity. We investigated to what extent a genetic risk score (GRS) based on recently published, novel migraine-associated SNPs is associated with migraine prevalence, subtypes and severity in a large population-based sample. The sample comprised 446 subjects with migraine and 2511 controls from the CoLaus/PsyCoLaus study. Fifty-four SNPs earlier associated with migraine were selected. SNPs with a low impact on migraine prevalence in our sample were excluded using random forest. We combined the remaining 21 SNPs into a GRS and analyzed the association with migraine using logistic regression models. The GRS was significantly associated with migraine (OR = 1.56, p = 0.02) and migraine without aura (MWOA) (OR = 2.01, p = 0.003), but not with migraine with aura (MWA). The GRS was not associated with migraine frequency, intensity or interference with daily activities. We show that a GRS combining multiple genetic risk variants is associated with MWOA but not MWA, suggesting a different genetic susceptibility background underlying the two forms of migraine.
[Mh] Termos MeSH primário: Enxaqueca com Aura/genética
Enxaqueca sem Aura/genética
Polimorfismo de Nucleotídeo Único
[Mh] Termos MeSH secundário: Adulto
Idoso
Estudos de Casos e Controles
Estudos de Coortes
Feminino
Loci Gênicos
Técnicas de Genotipagem
Seres Humanos
Modelos Logísticos
Masculino
Meia-Idade
Prevalência
Fatores de Risco
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170825
[Lr] Data última revisão:
170825
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170629
[St] Status:MEDLINE
[do] DOI:10.1007/s00439-017-1816-5


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[PMID]:28356463
[Au] Autor:DaSilva AF; Nascimento TD; Jassar H; Heffernan J; Toback RL; Lucas S; DosSantos MF; Bellile EL; Boonstra PS; Taylor JMG; Casey KL; Koeppe RA; Smith YR; Zubieta JK
[Ad] Endereço:From the Headache & Orofacial Pain Effort (H.O.P.E.), Biologic & Materials Sciences Department, School of Dentistry (A.F.D., T.D.N., H.J., R.L.T., S.L., M.F.D.), Translational Neuroimaging Laboratory, Molecular & Behavioral Neuroscience Institute (A.F.D., J.H.. J.-K.Z.), Department of Bi
[Ti] Título:Dopamine D2/D3 imbalance during migraine attack and allodynia in vivo.
[So] Source:Neurology;88(17):1634-1641, 2017 Apr 25.
[Is] ISSN:1526-632X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To evaluate in vivo the dynamics of endogenous dopamine (DA) neurotransmission during migraine ictus with allodynia. METHODS: We examined 8 episodic migraineurs and 8 healthy controls (HC) using PET with [ C]raclopride. The uptake measure of [ C]raclopride, nondisplaceable binding potential (BP ), would increase when there was a reduction in endogenous DA release. The opposite is true for a decrease in [ C]raclopride BP . Patients were scanned twice: one PET session was during a spontaneous migraine ictus at rest, followed by a sustained thermal pain threshold (STPT) challenge on the trigeminal region, eliciting an allodynia experience; another was during interictal phase. RESULTS: Striatal BP of [ C]raclopride in migraineurs did not differ from HC. We found a significant increase in [ C]raclopride BP in the striatum region of migraineurs during both headache attack and allodynia relative to interictal phase. However, when compared to the migraine attack at rest, migraineurs during the STPT challenge had a significant sudden reduction in [ C]raclopride BP in the insula. Such directional change was also observed in the caudate of HC relative to the interictal phase during challenge. Furthermore, ictal changes in [ C]raclopride BP in migraineurs at rest were positively correlated with the chronicity of migraine attacks, and negatively correlated with the frequency during challenge. CONCLUSIONS: Our findings demonstrate that there is an imbalanced uptake of [ C]raclopride during the headache attack and ictal allodynia, which indicates reduction and fluctuation in ictal endogenous DA release in migraineurs. Moreover, the longer the history and recurrence of migraine attacks, the lower the ictal endogenous DA release.
[Mh] Termos MeSH primário: Encéfalo/metabolismo
Hiperalgesia/metabolismo
Enxaqueca com Aura/metabolismo
Enxaqueca sem Aura/metabolismo
Receptores de Dopamina D2/metabolismo
Receptores de Dopamina D3/metabolismo
[Mh] Termos MeSH secundário: Adulto
Mapeamento Encefálico
Dopamina/metabolismo
Feminino
Temperatura Alta
Seres Humanos
Hiperalgesia/diagnóstico por imagem
Masculino
Enxaqueca com Aura/diagnóstico por imagem
Enxaqueca sem Aura/diagnóstico por imagem
Estimulação Física
Tomografia por Emissão de Pósitrons
Racloprida
Compostos Radiofarmacêuticos
Descanso
Transmissão Sináptica/fisiologia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DRD2 protein, human); 0 (DRD3 protein, human); 0 (Radiopharmaceuticals); 0 (Receptors, Dopamine D2); 0 (Receptors, Dopamine D3); 430K3SOZ7G (Raclopride); VTD58H1Z2X (Dopamine)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170515
[Lr] Data última revisão:
170515
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170331
[St] Status:MEDLINE
[do] DOI:10.1212/WNL.0000000000003861


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[PMID]:28264095
[Au] Autor:De Giuli V; Grassi M; Lodigiani C; Patella R; Zedde M; Gandolfo C; Zini A; DeLodovici ML; Paciaroni M; Del Sette M; Azzini C; Toriello A; Musolino R; Calabrò RS; Bovi P; Sessa M; Adami A; Silvestrelli G; Cavallini A; Marcheselli S; Bonifati DM; Checcarelli N; Tancredi L; Chiti A; Lotti EM; Del Zotto E; Tomelleri G; Spalloni A; Giorli E; Costa P; Poli L; Morotti A; Caria F; Lanari A; Giacalone G; Ferrazzi P; Giossi A; Piras V; Massucco D; D'Amore C; Di Lisi F; Casetta I; Cucurachi L; Cotroneo M; De Vito A; Coloberti E; Rasura M; Simone AM; Gamba M; Cerrato P; Italian Project on Stroke in Young Adults Investigators
[Ad] Endereço:Dipartimento di Scienze Cliniche e Sperimentali, Clinica Neurologica, Università degli Studi di Brescia, Brescia, Italia.
[Ti] Título:Association Between Migraine and Cervical Artery Dissection: The Italian Project on Stroke in Young Adults.
[So] Source:JAMA Neurol;74(5):512-518, 2017 May 01.
[Is] ISSN:2168-6157
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Importance: Although sparse observational studies have suggested a link between migraine and cervical artery dissection (CEAD), any association between the 2 disorders is still unconfirmed. This lack of a definitive conclusion might have implications in understanding the pathogenesis of both conditions and the complex relationship between migraine and ischemic stroke (IS). Objective: To investigate whether a history of migraine and its subtypes is associated with the occurrence of CEAD. Design, Setting, and Participants: A prospective cohort study of consecutive patients aged 18 to 45 years with first-ever acute ischemic stroke enrolled in the multicenter Italian Project on Stroke in Young Adults was conducted between January 1, 2000, and June 30, 2015. In a case-control design, the study assessed whether the frequency of migraine and its subtypes (presence or absence of an aura) differs between patients whose IS was due to CEAD (CEAD IS) and those whose IS was due to a cause other than CEAD (non-CEAD IS) and compared the characteristics of patients with CEAD IS with and without migraine. Main Outcomes and Measures: Frequency of migraine and its subtypes in patients with CEAD IS vs non-CEAD IS. Results: Of the 2485 patients (mean [SD] age, 36.8 [7.1] years; women, 1163 [46.8%]) included in the registry, 334 (13.4%) had CEAD IS and 2151 (86.6%) had non-CEAD IS. Migraine was more common in the CEAD IS group (103 [30.8%] vs 525 [24.4%], P = .01), and the difference was mainly due to migraine without aura (80 [24.0%] vs 335 [15.6%], P < .001). Compared with migraine with aura, migraine without aura was independently associated with CEAD IS (OR, 1.74; 95% CI, 1.30-2.33). The strength of this association was higher in men (OR, 1.99; 95% CI, 1.31-3.04) and in patients 39.0 years or younger (OR, 1.82; 95% CI, 1.22-2.71). The risk factor profile was similar in migrainous and non-migrainous patients with CEAD IS (eg, hypertension, 20 [19.4%] vs 57 [24.7%], P = .29; diabetes, 1 [1.0%] vs 3 [1.3%], P > .99). Conclusions and Relevance: In patients with IS aged 18 to 45 years, migraine, especially migraine without aura, is consistently associated with CEAD. This finding suggests common features and warrants further analyses to elucidate the underlying biologic mechanisms.
[Mh] Termos MeSH primário: Isquemia Encefálica/epidemiologia
Doenças Arteriais Intracranianas/epidemiologia
Enxaqueca com Aura/epidemiologia
Enxaqueca sem Aura/epidemiologia
Sistema de Registros
Acidente Vascular Cerebral/epidemiologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Fatores Etários
Estudos de Casos e Controles
Feminino
Seres Humanos
Itália/epidemiologia
Masculino
Meia-Idade
Estudos Prospectivos
Fatores Sexuais
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; MULTICENTER STUDY
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170630
[Lr] Data última revisão:
170630
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170307
[St] Status:MEDLINE
[do] DOI:10.1001/jamaneurol.2016.5704


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[PMID]:28124204
[Au] Autor:Faragó P; Tuka B; Tóth E; Szabó N; Király A; Csete G; Szok D; Tajti J; Párdutz Á; Vécsei L; Kincses ZT
[Ad] Endereço:Department of Neurology, Neuroimaging Research Group, Albert Szent-Györgyi, Clinical Center, University of Szeged, Semmelweis u. 6, H-6725, Szeged, Hungary.
[Ti] Título:Interictal brain activity differs in migraine with and without aura: resting state fMRI study.
[So] Source:J Headache Pain;18(1):8, 2017 Dec.
[Is] ISSN:1129-2377
[Cp] País de publicação:Italy
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Migraine is one of the most severe primary headache disorders. The nature of the headache and the associated symptoms during the attack suggest underlying functional alterations in the brain. In this study, we examined amplitude, the resting state fMRI fluctuation in migraineurs with and without aura (MWA, MWoA respectively) and healthy controls. METHODS: Resting state functional MRI images and T1 high-resolution images were acquired from all participants. For data analysis we compared the groups (MWA-Control, MWA-MWoA, MWoA-Control). The resting state networks were identified by MELODIC. The mean time courses of the networks were identified for each participant for all networks. The time-courses were decomposed into five frequency bands by discrete wavelet decomposition. The amplitude of the frequency-specific activity was compared between groups. Furthermore, the preprocessed resting state images were decomposed by wavelet analysis into five specific frequency bands voxel-wise. The voxel-wise amplitudes were compared between groups by non-parametric permutation test. RESULTS: In the MWA-Control comparison the discrete wavelet decomposition found alterations in the lateral visual network. Higher activity was measured in the MWA group in the highest frequency band (0.16-0.08 Hz). In case of the MWA-MWoA comparison all networks showed higher activity in the 0.08-0.04 Hz frequency range in MWA, and the lateral visual network in in higher frequencies. In MWoA-Control comparison only the default mode network revealed decreased activity in MWoA group in the 0.08-0.04 Hz band. The voxel-wise frequency specific analysis of the amplitudes found higher amplitudes in MWA as compared to MWoA in the in fronto-parietal regions, anterior cingulate cortex and cerebellum. DISCUSSION: The amplitude of the resting state fMRI activity fluctuation is higher in MWA than in MWoA. These results are in concordance with former studies, which found cortical hyperexcitability in MWA.
[Mh] Termos MeSH primário: Encéfalo/fisiopatologia
Enxaqueca com Aura/fisiopatologia
Enxaqueca sem Aura/fisiopatologia
[Mh] Termos MeSH secundário: Adulto
Encéfalo/diagnóstico por imagem
Feminino
Seres Humanos
Imagem por Ressonância Magnética
Masculino
Meia-Idade
Enxaqueca com Aura/diagnóstico por imagem
Enxaqueca sem Aura/diagnóstico por imagem
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170127
[St] Status:MEDLINE
[do] DOI:10.1186/s10194-016-0716-8


  9 / 675 MEDLINE  
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Carvalho, Deusvenir de Souza
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[PMID]:28122382
[Au] Autor:Agessi LM; Villa TR; Carvalho DS; Pereira LD
[Ad] Endereço:Department of Speech Pathology and Audiology, Federal University of São Paulo, UNIFESP, São Paulo, Brazil.
[Ti] Título:Auditory Processing in Children with Migraine: A Controlled Study.
[So] Source:Neuropediatrics;48(2):123-126, 2017 Apr.
[Is] ISSN:1439-1899
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:This study aimed to investigate central auditory processing performance in children with migraine and compared with controls without headache. Twenty-eight children of both sexes, aged between 8 and 12 years, diagnosed with migraine with and without aura, and a control group of the same age range and with no headache history, were included. Gaps-in-noise (GIN), duration pattern test (DPT), synthetic sentence identification (SSI) test, and nonverbal dichotic test (NVDT) were used to assess central auditory processing performance. Children with migraine performed significantly worse in DPT, SSI test, and NVDT when compared with controls without headache; however, no significant differences were found in the GIN test. Children with migraine demonstrate impairment in the physiologic mechanism of temporal processing and selective auditory attention. In our short communication, migraine could be related to impaired central auditory processing in children.
[Mh] Termos MeSH primário: Percepção Auditiva
Enxaqueca com Aura/fisiopatologia
Enxaqueca sem Aura/fisiopatologia
[Mh] Termos MeSH secundário: Estimulação Acústica/métodos
Atenção
Transtornos da Percepção Auditiva/complicações
Transtornos da Percepção Auditiva/fisiopatologia
Transtornos da Percepção Auditiva/psicologia
Criança
Feminino
Testes Auditivos
Seres Humanos
Testes de Linguagem
Masculino
Memória
Enxaqueca com Aura/complicações
Enxaqueca com Aura/psicologia
Enxaqueca sem Aura/complicações
Enxaqueca sem Aura/psicologia
Testes Neuropsicológicos
[Pt] Tipo de publicação:CONTROLLED CLINICAL TRIAL; JOURNAL ARTICLE
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170417
[Lr] Data última revisão:
170417
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170126
[St] Status:MEDLINE
[do] DOI:10.1055/s-0037-1598046


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[PMID]:28083761
[Au] Autor:Abanoz Y; Gülen Abanoz Y; Gündüz A; Uludüz D; Ince B; Yavuz B; Göksan B
[Ad] Endereço:Department of Neurology, Cerrahpasa School of Medicine, Istanbul University, K.M.Pasa, 34098, Istanbul, Turkey. yasinabanoz83@yahoo.com.
[Ti] Título:Migraine as a risk factor for young patients with ischemic stroke: a case-control study.
[So] Source:Neurol Sci;38(4):611-617, 2017 Apr.
[Is] ISSN:1590-3478
[Cp] País de publicação:Italy
[La] Idioma:eng
[Ab] Resumo:Studies have suggested a possible association of migraine and increased risk of ischemic stroke in young adults, particularly in smokers and in women who use oral contraceptive drugs. We aimed to analyze the association between migraine and ischemic stroke in young population in a hospital-based cohort. We included 202 consecutive patients with the diagnosis of ischemic stroke who were between 15 and 50 years and age- and gender-matched 250 volunteers with no history of stroke. All participants were interviewed using a questionnaire for migraine. Localization of ischemic lesion was classified as anterior and posterior circulation according to neuroimaging findings. The cause of ischemic lesion and all risk factors were recorded. Undetermined etiology was the most frequent (43.1%) and the most common determined cause was cardioembolism (22.3%) in young stroke patients. Frequency of migraine was 30.2% among patients with stroke whereas 16.8% of healthy subjects had migraine (p = 0.001). Migraine with aura was significantly more common among patients with stroke compared to healthy subjects (18.3 vs 4.4%; p = 0.000) whereas the frequency of migraine without aura was similar in both groups (11.9 vs 12.4%). Using logistic regression, migraine with aura was shown to be an independent risk factor for ischemic stroke in young population (p = 0.000) and separate analysis for gender demonstrated that it was only a risk factor for women (p = 0.009) but not for men (p = 0.107). Migraine with aura was found to be more common in ischemic stroke in young patients. It was an independent risk factor in women.
[Mh] Termos MeSH primário: Isquemia Encefálica/epidemiologia
Enxaqueca com Aura/epidemiologia
Enxaqueca sem Aura/epidemiologia
Acidente Vascular Cerebral/epidemiologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Fatores Etários
Isquemia Encefálica/etiologia
Estudos de Casos e Controles
Estudos de Coortes
Feminino
Seres Humanos
Modelos Logísticos
Masculino
Meia-Idade
Fatores de Risco
Fatores Sexuais
Acidente Vascular Cerebral/etiologia
Inquéritos e Questionários
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1704
[Cu] Atualização por classe:171013
[Lr] Data última revisão:
171013
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170114
[St] Status:MEDLINE
[do] DOI:10.1007/s10072-017-2810-3



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