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[PMID]:28741257
[Au] Autor:Joshi S; Rizzoli P; Loder E
[Ad] Endereço:Clinical Pharmacy Practice, MCPHS University College of Pharmacy, Worcester, USA.
[Ti] Título:The comorbidity burden of patients with cluster headache: a population-based study.
[So] Source:J Headache Pain;18(1):76, 2017 Dec.
[Is] ISSN:1129-2377
[Cp] País de publicação:Italy
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Evidence is limited regarding the comorbidity burden of patients with cluster headache (CH). We aimed to characterize comorbid conditions in a cohort of CH patients diagnosed by headache experts, using electronic health record information from the Partners Research Patient Data Registry (RPDR). METHODS: We identified and reviewed the charts of unique patients diagnosed by headache specialists over an 11-year period, and a set of matched controls. Patients were categorized as having Definite, Unconfirmed or no CH. We calculated the prevalence of and tested for statistically significant differences of selected comorbid conditions in these populations. RESULTS: An RPDR query identified 170 patients with a free text or ICD diagnosis of cluster headache. 15 records belonging to Partners employees were excluded. 75 patients met diagnostic criteria for CH (Definite CH). 22 had headaches with some features of CH but the diagnosis was uncertain (Unconfirmed CH). In 58 the diagnosis was determined to be inaccurate due to data entry errors. Patients with Definite CH had an average age of 43.4 years; 80% were male. The average time from CH onset to diagnosis was 12.7 years (range 1-51). The average number of yearly emergency department and outpatient visits for the group of Definite CH patients was 4.5 and 25.4, respectively, compared with 1.1 and 6.9 in controls. Of the 55 examined conditions, four were statistically significantly less common in patients with definite CH compared with controls (diabetes, musculoskeletal/orthopaedic problems, "other gastrointestinal diagnoses" and skin conditions) and four were statistically significantly more common (smoking, depression, dental disorders and deviated septum). CONCLUSIONS: In this large population-based study, we identified a surprisingly small number of patients who met strict diagnostic criteria for CH. In these patients, however, we identified a distinct pattern of selected comorbidities. The pattern is somewhat but not entirely consistent with that of the "classic" CH patient depicted in the medical literature. CH patients are frequently diagnosed with sinus or dental problems. Many experience substantial delay in receiving a diagnosis. These things may in part explain the high frequency of medical visits in this population. It is difficult to distinguish conditions that are genuinely comorbid with CH from those that reflect misdiagnoses or medical scrutiny of patients in frequent contact with the healthcare system.
[Mh] Termos MeSH primário: Cefaleia Histamínica/diagnóstico
Cefaleia Histamínica/epidemiologia
Efeitos Psicossociais da Doença
Vigilância da População
[Mh] Termos MeSH secundário: Adulto
Idoso
Estudos de Coortes
Comorbidade
Erros de Diagnóstico
Registros Eletrônicos de Saúde/tendências
Feminino
Seres Humanos
Masculino
Transtornos Mentais/diagnóstico
Transtornos Mentais/epidemiologia
Meia-Idade
Vigilância da População/métodos
Prevalência
Sistema de Registros
Fumar/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180306
[Lr] Data última revisão:
180306
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170726
[St] Status:MEDLINE
[do] DOI:10.1186/s10194-017-0785-3


  2 / 2344 MEDLINE  
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[PMID]:29174963
[Au] Autor:Hoffmann J; May A
[Ad] Endereço:Department of Systems Neuroscience, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
[Ti] Título:Diagnosis, pathophysiology, and management of cluster headache.
[So] Source:Lancet Neurol;17(1):75-83, 2018 Jan.
[Is] ISSN:1474-4465
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Cluster headache is a trigeminal autonomic cephalalgia characterised by extremely painful, strictly unilateral, short-lasting headache attacks accompanied by ipsilateral autonomic symptoms or the sense of restlessness and agitation, or both. The severity of the disorder has major effects on the patient's quality of life and, in some cases, might lead to suicidal ideation. Cluster headache is now thought to involve a synchronised abnormal activity in the hypothalamus, the trigeminovascular system, and the autonomic nervous system. The hypothalamus appears to play a fundamental role in the generation of a permissive state that allows the initiation of an episode, whereas the attacks are likely to require the involvement of the peripheral nervous system. Triptans are the most effective drugs to treat an acute cluster headache attack. Monoclonal antibodies against calcitonin gene-related peptide, a crucial neurotransmitter of the trigeminal system, are under investigation for the preventive treatment of cluster headache. These studies will increase our understanding of the disorder and perhaps reveal other therapeutic targets.
[Mh] Termos MeSH primário: Anestésicos Locais/farmacologia
Cefaleia Histamínica/tratamento farmacológico
Cefaleia Histamínica/etiologia
Cefaleia Histamínica/fisiopatologia
Lidocaína/farmacologia
Oxigênio/farmacologia
Triptaminas/farmacologia
[Mh] Termos MeSH secundário: Anestésicos Locais/administração & dosagem
Cefaleia Histamínica/diagnóstico
Seres Humanos
Lidocaína/administração & dosagem
Oxigênio/administração & dosagem
Triptaminas/administração & dosagem
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Anesthetics, Local); 0 (Tryptamines); 98PI200987 (Lidocaine); S88TT14065 (Oxygen)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171227
[Lr] Data última revisão:
171227
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171128
[St] Status:MEDLINE


  3 / 2344 MEDLINE  
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[PMID]:28387016
[Au] Autor:Tepper SJ; Caparso A
[Ad] Endereço:Department of Neurology, Geisel School of Medicine at Dartmouth, Hanover, NH, USA.
[Ti] Título:Sphenopalatine Ganglion (SPG): Stimulation Mechanism, Safety, and Efficacy.
[So] Source:Headache;57 Suppl 1:14-28, 2017 Apr.
[Is] ISSN:1526-4610
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To describe the history of and available data on sphenopalatine ganglion (SPG) neuromodulation in the treatment of headache up to the present. BACKGROUND: The SPG has been a therapeutic target to treat primary headache disorders for over 100 years. Multiple destructive lesions have also been tried with variable rate and duration of success. Neurostimulation of the SPG for cluster headache was first described in 2007. METHODS: This is not a systematic review. The authors review the anatomy and pathophysiology of the SPG and cluster headache and the important clinical trials, relating a history of how SPG neuromodulation reached the current state of approval in the European Union (EU) and pivotal registration study for cluster headache in the US. RESULTS: The EU approved SPG stimulation for cluster headache with a CE Mark in February of 2012. Since then, several EU countries have elected to reimburse implantation for cluster headache, and over 300 patients have been implanted worldwide. CONCLUSIONS: Success rates for implanted SPG neuromodulation in the experimental phase of the European randomized controlled trial, in the open label extension trial, and in the registry of patients implanted outside of the trial remain at about two-thirds of patients implanted being responders, defined as being able to terminate at least 50% of attacks or having at least a 50% decrease in attack frequency or both. A US pivotal registration study is underway to confirm these results and obtain FDA approval for this treatment for cluster headache patients. Further studies in migraine are also underway.
[Mh] Termos MeSH primário: Cefaleia Histamínica/fisiopatologia
Cefaleia Histamínica/terapia
Terapia por Estimulação Elétrica/métodos
Gânglios Parassimpáticos/fisiopatologia
[Mh] Termos MeSH secundário: Animais
Cefaleia Histamínica/patologia
Terapia por Estimulação Elétrica/efeitos adversos
Terapia por Estimulação Elétrica/instrumentação
Gânglios Parassimpáticos/patologia
Seres Humanos
Neuroestimuladores Implantáveis/efeitos adversos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170417
[Lr] Data última revisão:
170417
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170408
[St] Status:MEDLINE
[do] DOI:10.1111/head.13035


  4 / 2344 MEDLINE  
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[PMID]:28202701
[Au] Autor:Lund N; Barloese M; Petersen A; Haddock B; Jensen R
[Ad] Endereço:From the Danish Headache Center, Department of Neurology (N.L., A.P., R.J.), and Department of Clinical Physiology, Nuclear Medicine and PET (M.B., B.H.), Rigshospitalet-Glostrup, University of Copenhagen, Denmark. nunu.lund@regionh.dk.
[Ti] Título:Chronobiology differs between men and women with cluster headache, clinical phenotype does not.
[So] Source:Neurology;88(11):1069-1076, 2017 Mar 14.
[Is] ISSN:1526-632X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To describe differences between the sexes in the phenotype of cluster headache (CH) in a large, well-characterized clinical CH population. METHODS: Patients from the Danish CH survey aged 18-65 years, diagnosed with CH according to International Classification of Headache Disorders, second edition, completed questionnaires and structured interviews. RESULTS: A total of 351 patients with CH participated, with a male:female ratio of 2:1. The diurnal variation of attacks showed moments of peak prominence in men's attack cycle to be advanced by 1 hour compared to women's, despite no difference in self-reported bedtime or chronotype ( = 0.31). The onset of CH decreased with increasing age for both sexes. Diagnostic delay was numerically longer for men vs women (6.56 vs 5.50 years, = 0.21); however, more women had previously been misdiagnosed (61.1% vs 45.5%, < 0.01) and received the correct diagnosis at a tertiary headache center (38.8% vs 20.9%, < 0.001). Only minor sex differences in clinical characteristics were found but chronic CH was more prevalent in women compared to men (44.0% vs 31.9%, < 0.05). CONCLUSIONS: Despite a similar clinical phenotype, diurnal attack cycle is advanced by 1 hour in men with CH compared to women. Rhythmicity is a defining characteristic of CH and these findings suggest differences in the hypothalamus' influence on attack occurrence between the sexes. In addition, women were more often misdiagnosed and diagnosis in the primary or secondary sector more often failed. Furthermore, women had chronic CH more frequently than men. A long diagnostic delay and frequent misdiagnosis emphasize the need for increased awareness of CH in both sexes.
[Mh] Termos MeSH primário: Ritmo Circadiano
Cefaleia Histamínica/fisiopatologia
Caracteres Sexuais
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idade de Início
Idoso
Diagnóstico Tardio
Feminino
Seres Humanos
Masculino
Meia-Idade
Fenótipo
Sono/fisiologia
Estatísticas não Paramétricas
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; OBSERVATIONAL STUDY
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170522
[Lr] Data última revisão:
170522
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170217
[St] Status:MEDLINE
[do] DOI:10.1212/WNL.0000000000003715


  5 / 2344 MEDLINE  
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[PMID]:28197844
[Au] Autor:Gaul C; Magis D; Liebler E; Straube A
[Ad] Endereço:Department of Headache and Facial Pain, Migraine and Headache Clinic, Ölmühlweg 31, Königstein im Taunus, 61462, Germany. c.gaul@migraene-klinik.de.
[Ti] Título:Effects of non-invasive vagus nerve stimulation on attack frequency over time and expanded response rates in patients with chronic cluster headache: a post hoc analysis of the randomised, controlled PREVA study.
[So] Source:J Headache Pain;18(1):22, 2017 Dec.
[Is] ISSN:1129-2377
[Cp] País de publicação:Italy
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: In the PREVention and Acute treatment of chronic cluster headache (PREVA) study, attack frequency reductions from baseline were significantly more pronounced with non-invasive vagus nerve stimulation plus standard of care (nVNS + SoC) than with SoC alone. Given the intensely painful and frequent nature of chronic cluster headache attacks, additional patient-centric outcomes, including the time to and level of therapeutic response, were evaluated in a post hoc analysis of the PREVA study. FINDINGS: After a 2-week baseline phase, 97 patients with chronic cluster headache entered a 4-week randomised phase to receive nVNS + SoC (n = 48) or SoC alone (n = 49). All 92 patients who continued into a 4-week extension phase received nVNS + SoC. Compared with SoC alone, nVNS + SoC led to a significantly lower mean weekly attack frequency by week 2 of the randomised phase; the attack frequency remained significantly lower in the nVNS + SoC group through week 3 of the extension phase (P < 0.02). Attack frequencies in the nVNS + SoC group were significantly lower at all study time points than they were at baseline (P < 0.05). Response rates were significantly greater with nVNS + SoC than with SoC alone when response was defined as attack frequency reductions of ≥25%, ≥50%, and ≥75% from baseline (≥25% and ≥50%, P < 0.001; ≥75%, P = 0.009). The 100% response rate was 8% with nVNS + SoC and 0% with SoC alone. CONCLUSIONS: Prophylactic nVNS led to rapid, significant, and sustained reductions in chronic cluster headache attack frequency within 2 weeks after its addition to SoC and was associated with significantly higher ≥25%, ≥50%, and ≥75% response rates than SoC alone. The rapid decrease in weekly attack frequency justifies a 4-week trial period to identify responders to nVNS, with a high degree of confidence, among patients with chronic cluster headache.
[Mh] Termos MeSH primário: Cefaleia Histamínica/fisiopatologia
Cefaleia Histamínica/terapia
Estimulação do Nervo Vago
[Mh] Termos MeSH secundário: Adulto
Feminino
Seres Humanos
Masculino
Meia-Idade
Medição da Dor
Fatores de Tempo
Resultado do Tratamento
Estimulação do Nervo Vago/métodos
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170413
[Lr] Data última revisão:
170413
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170216
[St] Status:MEDLINE
[do] DOI:10.1186/s10194-017-0731-4


  6 / 2344 MEDLINE  
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[PMID]:28152528
[Au] Autor:Dirkx TH; Koehler PJ
[Ad] Endereço:Department of Neurology, Zuyderland Medical Centre, Heerlen, The Netherlands.
[Ti] Título:Post-Operative Cluster Headache Following Carotid Endarterectomy.
[So] Source:Eur Neurol;77(3-4):175-179, 2017.
[Is] ISSN:1421-9913
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Secondary cluster headache following carotid endarterectomy (CEA) is a rare condition and may help us understand the pathophysiology of primary cluster headache. SUMMARY: We describe 2 patients diagnosed with cluster headache, fulfilling the ICHD-IIIB criteria, following CEA. Neither of the patients had headache prior to surgery. They both responded to treatment with oxygen and verapamil. Recent medical literature does not describe any definite cases of cluster headache following CEA. Cluster-like headache has been reported in several studies in the 1990s. Recent studies in primary cluster headache patients show evidence for a central origin of cluster headache in which no peripheral drive seems necessary. Key Messages: Our findings may provide more insight into the pathophysiology and show how a peripheral cause may lead to cluster headache. We hypothesize a role of the trigemino-autonomic reflex. Damage to the carotid artery may activate this reflex and trigger cluster headache. Injury to the internal carotid artery may unleash attacks in patients who are predisposed to develop cluster headache. Further study on the subject is needed to resolve this issue.
[Mh] Termos MeSH primário: Cefaleia Histamínica/etiologia
Endarterectomia das Carótidas/efeitos adversos
Complicações Pós-Operatórias
[Mh] Termos MeSH secundário: Feminino
Seres Humanos
Masculino
Meia-Idade
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170927
[Lr] Data última revisão:
170927
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170203
[St] Status:MEDLINE
[do] DOI:10.1159/000456004


  7 / 2344 MEDLINE  
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[PMID]:28145655
[Au] Autor:Moon HS; Park JW; Lee KS; Chung CS; Kim BK; Kim JM; Sohn JH; Chu MK; Oh K; Cho SJ
[Ad] Endereço:Department of Neurology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.
[Ti] Título:Clinical Features of Cluster Headache Patients in Korea.
[So] Source:J Korean Med Sci;32(3):502-506, 2017 Mar.
[Is] ISSN:1598-6357
[Cp] País de publicação:Korea (South)
[La] Idioma:eng
[Ab] Resumo:Cluster headache (CH) is a rare underdiagnosed primary headache disorder with very severe unilateral pain and autonomic symptoms. Clinical characteristics of Korean patients with CH have not yet been reported. We analyzed the clinical features of CH patients from 11 university hospitals in Korea. Among a total of 200 patients with CH, only 1 patient had chronic CH. The average age of CH patients was 38.1 ± 8.9 years (range 19-60 years) and the average age of onset was 30.7 ± 10.3 years (range 10-57 years). The male-to-female ratio was 7:1 (2.9:1 among teen-onset and 11.7:1 among twenties-onset). Pain was very severe at 9.3 ± 1.0 on the visual analogue scale. The average duration of each attack was 100.6 ± 55.6 minutes and a bout of CH lasted 6.5 ± 4.5 weeks. Autonomic symptoms were present in 93.5% and restlessness or agitation was present in 43.5% of patients. Patients suffered 3.0 ± 3.5 (range 1-25) bouts over 7.3 ± 6.7 (range 1-30) years. Diurnal periodicity and season propensity were present in 68.5% and 44.0% of patients, respectively. There were no sex differences in associated symptoms or diurnal and seasonal periodicity. Korean CH patients had a high male-to-female ratio, relatively short bout duration, and low proportion of chronic CH, unlike CH patients in Western countries.
[Mh] Termos MeSH primário: Cefaleia Histamínica/diagnóstico
[Mh] Termos MeSH secundário: Adulto
Fatores Etários
Cefaleia Histamínica/patologia
Bases de Dados Factuais
Feminino
Hospitais Universitários
Seres Humanos
Masculino
Meia-Idade
Medição da Dor
Estudos Retrospectivos
Estações do Ano
Índice de Gravidade de Doença
Fatores Sexuais
Fumar
Inquéritos e Questionários
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170331
[Lr] Data última revisão:
170331
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170202
[St] Status:MEDLINE
[do] DOI:10.3346/jkms.2017.32.3.502


  8 / 2344 MEDLINE  
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[PMID]:28128461
[Au] Autor:Láinez MJ; Guillamón E
[Ad] Endereço:Department of Neurology, Hospital Clínico Universitario de Valencia, Valencia, Spain.
[Ti] Título:Cluster headache and other TACs: Pathophysiology and neurostimulation options.
[So] Source:Headache;57(2):327-335, 2017 Feb.
[Is] ISSN:1526-4610
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The trigeminal autonomic cephalalgias (TACs) are highly disabling primary headache disorders. There are several issues that remain unresolved in the understanding of the pathophysiology of the TACs, although activation of the trigeminal-autonomic reflex and ipsilateral hypothalamic activation both play a central role. The discovery of the central role of the hypothalamus led to its use as a therapeutic target. After the good results obtained with hypothalamic stimulation, other peripheral neuromodulation targets were tried in the management of refractory cluster headache (CH) and other TACs. METHODS: This review is a summary both of CH pathophysiology and of efficacy of the different neuromodulation techniques. RESULTS: In chronic cluster headache (CCH) patients, hypothalamic deep brain stimulation (DBS) produced a decrease in attack frequency of more than 50% in 60% of patients. Occipital nerve stimulation (ONS) also elicited favorable outcomes with a reduction of more than 50% of attacks in around 70% of patients with medically intractable CCH. Stimulation of the sphenopalatine ganglion (SPG) with a miniaturized implanted stimulator produced a clinically significant improvement in 68% of patients (acute, preventive, or both). Vagus nerve stimulation (VNS) with a portable device used in conjunction with standard of care in CH patients resulted in a reduction in the number of attacks. DBS and ONS have been used successfully in some cases of other TACs, including hemicrania continua (HC) and short-lasting unilateral headache attacks (SUNHA). CONCLUSIONS: DBS has good results, but it is a more invasive technique and can generate serious adverse events. ONS has good results, but frequent and not serious adverse events. SPG stimulation (SPGS) is also efficacious in the acute and prophylactic treatment of refractory cluster headache. At this moment, ONS and SPG stimulation techniques are recommended as first line therapy in refractory cluster patients. New recent non-invasive approaches such as the non-invasive vagal nerve stimulator (nVNS) have shown efficacy in a few trials and could be an interesting alternative in the management of CH, but require more testing and positive randomized controlled trials.
[Mh] Termos MeSH primário: Cefaleia Histamínica/fisiopatologia
Cefaleia Histamínica/terapia
Terapia por Estimulação Elétrica/métodos
[Mh] Termos MeSH secundário: Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170128
[St] Status:MEDLINE
[do] DOI:10.1111/head.12874


  9 / 2344 MEDLINE  
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[PMID]:28094022
[Au] Autor:Biedron A; Kacinski M; Steczkowska M; Swierczynska A
[Ad] Endereço:Chair of Pediatric and Adolescent Neurology, Department of Pediatric Neurology, Jagiellonian University, Cracow, Poland. Electronic address: aganow7@yahoo.com.
[Ti] Título:A case report of an adolescent with cluster headaches following neck trauma: Coincidence or trigger?
[So] Source:Neurol Neurochir Pol;51(2):170-173, 2017 Mar - Apr.
[Is] ISSN:0028-3843
[Cp] País de publicação:Poland
[La] Idioma:eng
[Ab] Resumo:Posttraumatic headaches usually have tension-type or migraine-like characteristics. A correlation between head trauma and cluster headaches (CH) has been previously reported. CH in children are rare and require thorough differential diagnosis. We present an original case of a 15-year-old boy with cluster headaches associated with allodynia probably evoked by a neck trauma. Severe headache attacks started one month after neck trauma. At the beginning clinical presentation of our patient's headaches was very misleading. Headaches were bilateral and associated with infection. Initial diagnosis of sinusitis was made. During further observation headaches have become unilateral with typical for CH associated symptoms and additionally with allodynia. Other causes of secondary CH like cervicogenic headaches, brain tumor and vascular malformation have been excluded. The boy has undergone prophylactic treatment based on flunarizine and gabapentin with good result. Possible pathogenesis of our patient's headaches has been proposed and diagnostic traps discussed.
[Mh] Termos MeSH primário: Cefaleia Histamínica/etiologia
Lesões do Pescoço/complicações
Ferimentos não Penetrantes/complicações
[Mh] Termos MeSH secundário: Adolescente
Aminas/uso terapêutico
Cefaleia Histamínica/reabilitação
Ácidos Cicloexanocarboxílicos/uso terapêutico
Quimioterapia Combinada
Flunarizina/uso terapêutico
Seguimentos
Seres Humanos
Comunicação Interdisciplinar
Colaboração Intersetorial
Masculino
Lesões do Pescoço/reabilitação
Recidiva
Retratamento
Ferimentos não Penetrantes/reabilitação
Ácido gama-Aminobutírico/uso terapêutico
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Amines); 0 (Cyclohexanecarboxylic Acids); 56-12-2 (gamma-Aminobutyric Acid); 6CW7F3G59X (gabapentin); R7PLA2DM0J (Flunarizine)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170118
[St] Status:MEDLINE


  10 / 2344 MEDLINE  
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[PMID]:27925184
[Au] Autor:de Coo I; van Dijk JM; Metzemaekers JD; Haan J
[Ad] Endereço:Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands.
[Ti] Título:A Case Report About Cluster-Tic Syndrome Due to Venous Compression of the Trigeminal Nerve.
[So] Source:Headache;57(4):654-657, 2017 Apr.
[Is] ISSN:1526-4610
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The term "cluster-tic syndrome" is used for the rare ipsilateral co-occurrence of attacks of cluster headache and trigeminal neuralgia. Medical treatment should combine treatment for cluster headache and trigeminal neuralgia, but is very often unsatisfactory. CASE: Here, we describe a 41-year-old woman diagnosed with cluster-tic syndrome who underwent microvascular decompression of the trigeminal nerve, primarily aimed at the "trigeminal neuralgia" part of her pain syndrome. After venous decompression of the trigeminal nerve both a decrease in trigeminal neuralgia and cluster headache attacks was seen. However, the headache did not disappear completely. Furthermore, she reported a decrease in pain intensity of the remaining cluster headache attacks. DISCUSSION: This case description suggests that venous vascular decompression in cluster-tic syndrome can be remarkably effective, both for trigeminal neuralgia and cluster headache.
[Mh] Termos MeSH primário: Cefaleia Histamínica/cirurgia
Cirurgia de Descompressão Microvascular/métodos
Nervo Trigêmeo/cirurgia
Neuralgia do Trigêmeo/cirurgia
[Mh] Termos MeSH secundário: Adulto
Encéfalo/diagnóstico por imagem
Cefaleia Histamínica/complicações
Cefaleia Histamínica/diagnóstico por imagem
Feminino
Lateralidade Funcional
Seres Humanos
Imagem por Ressonância Magnética
Neuralgia do Trigêmeo/complicações
Neuralgia do Trigêmeo/diagnóstico por imagem
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170418
[Lr] Data última revisão:
170418
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161208
[St] Status:MEDLINE
[do] DOI:10.1111/head.12990



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