Base de dados : MEDLINE
Pesquisa : C10.281.800 [Categoria DeCS]
Referências encontradas : 1633 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 164 ir para página                         

  1 / 1633 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29302035
[Au] Autor:Rijo-Ferreira F; Carvalho T; Afonso C; Sanches-Vaz M; Costa RM; Figueiredo LM; Takahashi JS
[Ad] Endereço:Graduate Program in Areas of Basic and Applied Biology, Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, 4099-002, Porto, Portugal.
[Ti] Título:Sleeping sickness is a circadian disorder.
[So] Source:Nat Commun;9(1):62, 2018 01 04.
[Is] ISSN:2041-1723
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Sleeping sickness is a fatal disease caused by Trypanosoma brucei, a unicellular parasite that lives in the bloodstream and interstitial spaces of peripheral tissues and the brain. Patients have altered sleep/wake cycles, body temperature, and endocrine profiles, but the underlying causes are unknown. Here, we show that the robust circadian rhythms of mice become phase advanced upon infection, with abnormal activity occurring during the rest phase. This advanced phase is caused by shortening of the circadian period both at the behavioral level as well as at the tissue and cell level. Period shortening is T. brucei specific and independent of the host immune response, as co-culturing parasites with explants or fibroblasts also shortens the clock period, whereas malaria infection does not. We propose that T. brucei causes an advanced circadian rhythm disorder, previously associated only with mutations in clock genes, which leads to changes in the timing of sleep.
[Mh] Termos MeSH primário: Transtornos do Sono do Ritmo Circadiano/fisiopatologia
Sono/fisiologia
Trypanosoma brucei brucei/fisiologia
Tripanossomíase Africana/parasitologia
[Mh] Termos MeSH secundário: Animais
Temperatura Corporal/fisiologia
Ritmo Circadiano/fisiologia
Fibroblastos/metabolismo
Fibroblastos/parasitologia
Expressão Gênica
Interações Hospedeiro-Parasita
Seres Humanos
Masculino
Camundongos Endogâmicos C57BL
Camundongos Transgênicos
Proteínas Circadianas Period/genética
Transtornos do Sono do Ritmo Circadiano/complicações
Fatores de Tempo
Tripanossomíase Africana/complicações
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Period Circadian Proteins)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180305
[Lr] Data última revisão:
180305
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180106
[St] Status:MEDLINE
[do] DOI:10.1038/s41467-017-02484-2


  2 / 1633 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29386442
[Au] Autor:Takada M
[Ad] Endereço:Faculty of Nursing and Rehabilitation, Chubu Gakuin University.
[Ti] Título:[Hygiene in Sleep: Problems of Sleeping Habits in Shift Workers].
[So] Source:Nihon Eiseigaku Zasshi;73(1):22-26, 2018.
[Is] ISSN:1882-6482
[Cp] País de publicação:Japan
[La] Idioma:jpn
[Ab] Resumo:Since World War II, Japan has achieved remarkable economic development and has become an advanced country. Particularly in the industrial field, a production system has been developed to reduce the loss of machining time by adopting a shiftwork in factories operating 24 hours a day, which contributes to the improvement of productivity. Nowadays, this shiftwork practice has spread from the industrial field to other businesses such as 24-hour entertainment facilities and convenience stores, which lead to sleep deprivation in Japanese society. Even at home, certain conditions adversely affect sleeping habits. We are concerned about the risks of physical and mental health, impairments posed by the use of tablets, PCs, smartphones, and other devices so popular in today's Japan, as they delay sleep. It is urgent to improve poor sleeping habits because their outcomes such as sleep disorders and deprivation may also lead to traffic and industrial accidents.
[Mh] Termos MeSH primário: Saúde do Trabalhador
Jornada de Trabalho em Turnos/efeitos adversos
Privação do Sono/etiologia
Transtornos do Sono do Ritmo Circadiano/etiologia
Sono/fisiologia
[Mh] Termos MeSH secundário: Acidentes de Trabalho/prevenção & controle
Acidentes de Trânsito/prevenção & controle
Ritmo Circadiano
Feminino
Promoção da Saúde
Seres Humanos
Japão
Estilo de Vida
Masculino
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180228
[Lr] Data última revisão:
180228
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180202
[St] Status:MEDLINE
[do] DOI:10.1265/jjh.73.22


  3 / 1633 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28449894
[Au] Autor:Fernandez F; Nyhuis CC; Anand P; Demara BI; Ruby NF; Spanò G; Clark C; Edgin JO
[Ad] Endereço:Departments of Psychology and Neurology, BIO5 Institute, University of Arizona, Tucson, USA; Evelyn F. McKnight Brain Institute, University of Arizona, Tucson, USA. Electronic address: FabianF@email.arizona.edu.
[Ti] Título:Young children with Down syndrome show normal development of circadian rhythms, but poor sleep efficiency: a cross-sectional study across the first 60 months of life.
[So] Source:Sleep Med;33:134-144, 2017 May.
[Is] ISSN:1878-5506
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: To evaluate sleep consolidation and circadian activity rhythms in infants and toddlers with Down syndrome (DS) under light and socially entrained conditions within a familiar setting. Given previous human and animal data suggesting intact circadian regulation of melatonin across the day and night, it was hypothesized that behavioral indices of circadian rhythmicity would likewise be intact in the sample with DS. METHODS: A cross-sectional study of 66 infants and young children with DS, aged 5-67 months, and 43 typically developing age-matched controls. Sleep and measures of circadian robustness or timing were quantified using continuous in-home actigraphy recordings performed over seven days. Circadian robustness was quantified via time series analysis of rest-activity patterns. Phase markers of circadian timing were calculated alongside these values. Sleep efficiency was also estimated based on the actigraphy recordings. RESULTS: This study provided further evidence that general sleep quality is poor in infants and toddlers with DS, a population that has sleep apnea prevalence as high as 50% during the preschool years. Despite poor sleep quality, circadian rhythm and phase were preserved in children with DS and displayed similar developmental trajectories in cross-sectional comparisons with a typically developing (TD) cohort. In line with past work, lower sleep efficiency scores were quantified in the group with DS relative to TD children. Infants born with DS exhibited the worst sleep fragmentation; however, in both groups, sleep efficiency and consolidation increased across age. Three circadian phase markers showed that 35% of the recruitment sample with DS was phase-advanced to an earlier morning schedule, suggesting significant within-group variability in the timing of their daily activity rhythms. CONCLUSIONS: Circadian rhythms of wake and sleep are robust in children born with DS. The present results suggest that sleep fragmentation and any resultant cognitive deficits are likely not confounded by corresponding deficits in circadian rhythms.
[Mh] Termos MeSH primário: Ritmo Circadiano/fisiologia
Síndrome de Down/complicações
Síndromes da Apneia do Sono/epidemiologia
Transtornos do Sono do Ritmo Circadiano/fisiopatologia
[Mh] Termos MeSH secundário: Actigrafia/métodos
Criança
Pré-Escolar
Estudos Transversais
Síndrome de Down/diagnóstico
Síndrome de Down/fisiopatologia
Feminino
Seres Humanos
Lactente
Luz/efeitos adversos
Masculino
Melatonina/metabolismo
Prevalência
Síndromes da Apneia do Sono/diagnóstico
Privação do Sono/fisiopatologia
Distúrbios do Início e da Manutenção do Sono/diagnóstico
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Nm] Nome de substância:
JL5DK93RCL (Melatonin)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180216
[Lr] Data última revisão:
180216
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170429
[St] Status:MEDLINE


  4 / 1633 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28470121
[Au] Autor:Cheng P; Tallent G; Bender TJ; Tran KM; Drake CL
[Ad] Endereço:Henry Ford Health System, Detroit, Michigan.
[Ti] Título:Shift Work and Cognitive Flexibility: Decomposing Task Performance.
[So] Source:J Biol Rhythms;32(2):143-153, 2017 Apr.
[Is] ISSN:1552-4531
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Deficits in cognitive functioning associated with shift work are particularly relevant to occupational performance; however, few studies have examined how cognitive functioning is associated with specific components of shift work. This observational study examined how circadian phase, nocturnal sleepiness, and daytime insomnia in a sample of shift workers ( N = 30) were associated with cognitive flexibility during the night shift. Cognitive flexibility was measured using a computerized task-switching paradigm, which produces 2 indexes of flexibility: switch cost and set inhibition. Switch cost represents the additional cognitive effort required in switching to a different task and can impact performance when multitasking is involved. Set inhibition is the efficiency in returning to previously completed tasks and represents the degree of cognitive perseveration, which can lead to reduced accuracy. Circadian phase was measured via melatonin assays, nocturnal sleepiness was assessed using the Multiple Sleep Latency Test, and daytime insomnia was assessed using the Insomnia Severity Index. Results indicated that those with an earlier circadian phase, insomnia, and sleepiness exhibited reduced cognitive flexibility; however, specific components of cognitive flexibility were differentially associated with circadian phase, insomnia, and sleepiness. Individuals with an earlier circadian phase (thus more misaligned to the night shift) exhibited larger switch costs, which was also associated with reduced task efficiency. Shift workers with more daytime insomnia demonstrated difficulties with cognitive inhibition, whereas nocturnal sleepiness was associated with difficulties in reactivating previous tasks. Deficits in set inhibition were also related to reduced accuracy and increased perseverative errors. Together, this study indicates that task performance deficits in shift work are complex and are variably impacted by different mechanisms. Future research may examine phenotypic differences in shift work and the associated consequences. Results also suggest that fatigue risk management strategies may benefit from increased scope and specificity in assessment of sleep, sleepiness, and circadian rhythms in shift workers.
[Mh] Termos MeSH primário: Cognição
Jornada de Trabalho em Turnos
Análise e Desempenho de Tarefas
Tolerância ao Trabalho Programado
[Mh] Termos MeSH secundário: Adulto
Ritmo Circadiano
Feminino
Seres Humanos
Luz
Masculino
Meia-Idade
Gestão de Riscos
Sono
Transtornos do Sono do Ritmo Circadiano
Distúrbios do Início e da Manutenção do Sono
Fases do Sono
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; OBSERVATIONAL STUDY
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180126
[Lr] Data última revisão:
180126
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170505
[St] Status:MEDLINE
[do] DOI:10.1177/0748730417699309


  5 / 1633 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
[PMID]:29256578
[Au] Autor:Blake N
[Ti] Título:ANMF PARTICIPATES IN INTERNATIONAL NURSING SYMPOSIUM ON SHIFT WORK.
[So] Source:Aust Nurs Midwifery J;24(7):11, 2017 02.
[Is] ISSN:2202-7114
[Cp] País de publicação:Australia
[La] Idioma:eng
[Ab] Resumo:Nurses and other health workers have long understood the often deleterious impacts that shift work can have on sleep, wellbeing and performance at work.
[Mh] Termos MeSH primário: Recursos Humanos de Enfermagem
Admissão e Escalonamento de Pessoal
Tolerância ao Trabalho Programado
[Mh] Termos MeSH secundário: Congressos como Assunto
Seres Humanos
Transtornos do Sono do Ritmo Circadiano
Sociedades de Enfermagem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180118
[Lr] Data última revisão:
180118
[Sb] Subgrupo de revista:N
[Da] Data de entrada para processamento:171220
[St] Status:MEDLINE


  6 / 1633 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29059251
[Au] Autor:Paech GM; Crowley SJ; Fogg LF; Eastman CI
[Ad] Endereço:Biological Rhythms Research Laboratory, Department of Behavioral Sciences, Rush University Medical Center, Chicago, Illinois, United States of America.
[Ti] Título:Advancing the sleep/wake schedule impacts the sleep of African-Americans more than European-Americans.
[So] Source:PLoS One;12(10):e0186887, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:There are differences in sleep duration between Blacks/African-Americans and Whites/European-Americans. Recently, we found differences between these ancestry groups in the circadian system, such as circadian period and the magnitude of phase shifts. Here we document the role of ancestry on sleep and cognitive performance before and after a 9-h advance in the sleep/wake schedule similar to flying east or having a large advance in sleep times due to shiftwork, both of which produce extreme circadian misalignment. Non-Hispanic African and European-Americans (N = 20 and 17 respectively, aged 21-43 years) were scheduled to four baseline days each with 8 h time in bed based on their habitual sleep schedule. This sleep/wake schedule was then advanced 9 h earlier for three days. Sleep was monitored using actigraphy. During the last two baseline/aligned days and the first two advanced/misaligned days, beginning 2 h after waking, cognitive performance was measured every 3 h using the Automated Neuropsychological Assessment Metrics (ANAM) test battery. Mixed model ANOVAs assessed the effects of ancestry (African-American or European-American) and condition (baseline/aligned or advanced/misaligned) on sleep and cognitive performance. There was decreased sleep and impaired performance in both ancestry groups during the advanced/misaligned days compared to the baseline/aligned days. In addition, African-Americans obtained less sleep than European-Americans, especially on the first two days of circadian misalignment. Cognitive performance did not differ between African-Americans and European-Americans during baseline days. During the two advanced/misaligned days, however, African-Americans tended to perform slightly worse compared to European-Americans, particularly at times corresponding to the end of the baseline sleep episodes. Advancing the sleep/wake schedule, creating extreme circadian misalignment, had a greater impact on the sleep of African-Americans than European-Americans. Ancestry differences in sleep appear to be exacerbated when the sleep/wake schedule is advanced, which may have implications for individuals undertaking shiftwork and transmeridian travel.
[Mh] Termos MeSH primário: Afroamericanos
Grupo com Ancestrais do Continente Europeu
Sono
Vigília
[Mh] Termos MeSH secundário: Adulto
Seres Humanos
Transtornos do Sono do Ritmo Circadiano
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171113
[Lr] Data última revisão:
171113
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171024
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0186887


  7 / 1633 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
[PMID]:28845960
[Au] Autor:Burman D
[Ad] Endereço:Latterman Family Health Center, 2347 Fifth Ave, McKeesport, PA 15132.
[Ti] Título:Sleep Disorders: Circadian Rhythm Sleep-Wake Disorders.
[So] Source:FP Essent;460:33-36, 2017 Sep.
[Is] ISSN:2159-3000
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Shift work sleep disorder is a common problem in industrialized countries because of the need for occupations and services to continue to function 24 hours/day. Approximately 20% of employed adults in the United States are engaged in shift work. Shift work sleep disorder is diagnosed if there is a report of insomnia or excessive sleepiness for at least 3 months associated with a recurring work schedule that overlaps the usual time for sleep. Shift work is associated with an increased occurrence of metabolic disorders, such as insulin resistance, diabetes, dyslipidemia, and metabolic syndrome, and it has been implicated in weight gain and cognitive impairment. There is evidence of increased absenteeism in night workers compared with day workers. A planned sleep schedule, timed bright light exposure, timed melatonin administration, and stimulants or drugs promoting alertness can be used to manage shift work sleep disorder. Jet lag is characterized by a misalignment between internal circadian rhythms and local time caused by rapid travel across at least two time zones. Not all travelers experience jet lag; risk factors include age, number of time zones crossed, and circadian preference. Management includes timed melatonin along with optional timed and dosed bright light exposure.
[Mh] Termos MeSH primário: Ritmo Circadiano/fisiologia
Transtornos do Sono do Ritmo Circadiano/prevenção & controle
Transtornos do Sono do Ritmo Circadiano/fisiopatologia
Higiene do Sono
Tolerância ao Trabalho Programado/fisiologia
[Mh] Termos MeSH secundário: Seres Humanos
Melatonina/metabolismo
Sono
Vigília
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
JL5DK93RCL (Melatonin)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171026
[Lr] Data última revisão:
171026
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170829
[St] Status:MEDLINE


  8 / 1633 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28838129
[Au] Autor:Li P; Morris CJ; Patxot M; Yugay T; Mistretta J; Purvis TE; Scheer FAJL; Hu K
[Ad] Endereço:Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA.
[Ti] Título:Reduced Tolerance to Night Shift in Chronic Shift Workers: Insight From Fractal Regulation.
[So] Source:Sleep;40(7), 2017 Jul 01.
[Is] ISSN:1550-9109
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Study Objectives: Healthy physiology is characterized by fractal regulation (FR) that generates similar structures in the fluctuations of physiological outputs at different time scales. Perturbed FR is associated with aging and age-related pathological conditions. Shift work, involving repeated and chronic exposure to misaligned environmental and behavioral cycles, disrupts circadian coordination. We tested whether night shifts perturb FR in motor activity and whether night shifts affect FR in chronic shift workers and non-shift workers differently. Methods: We studied 13 chronic shift workers and 14 non-shift workers as controls using both field and in-laboratory experiments. In the in-laboratory study, simulated night shifts were used to induce a misalignment between the endogenous circadian pacemaker and the sleep-wake cycles (ie, circadian misalignment) while environmental conditions and food intake were controlled. Results: In the field study, we found that FR was robust in controls but broke down in shift workers during night shifts, leading to more random activity fluctuations as observed in patients with dementia. The night shift effect was present even 2 days after ending night shifts. The in-laboratory study confirmed that night shifts perturbed FR in chronic shift workers and showed that FR in controls was more resilience to the circadian misalignment. Moreover, FR during real and simulated night shifts was more perturbed in those who started shift work at older ages. Conclusions: Chronic shift work causes night shift intolerance, which is probably linked to the degraded plasticity of the circadian control system.
[Mh] Termos MeSH primário: Ritmo Circadiano/fisiologia
Fractais
Tolerância ao Trabalho Programado/fisiologia
Tolerância ao Trabalho Programado/psicologia
[Mh] Termos MeSH secundário: Adulto
Estudos de Casos e Controles
Meio Ambiente
Comportamento Alimentar
Feminino
Seres Humanos
Masculino
Meia-Idade
Sono/fisiologia
Transtornos do Sono do Ritmo Circadiano/fisiopatologia
Transtornos do Sono do Ritmo Circadiano/psicologia
Vigília/fisiologia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171102
[Lr] Data última revisão:
171102
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170826
[St] Status:MEDLINE
[do] DOI:10.1093/sleep/zsx092


  9 / 1633 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
Texto completo SciELO Saúde Pública
[PMID]:28678902
[Au] Autor:Marqueze EC; Nicola ACB; Diniz DHMD; Fischer FM
[Ad] Endereço:Departamento de Epidemiologia. Programa de Pós-Graduação em Saúde Coletiva. Universidade Católica de Santos. Santos, SP, Brasil.
[Ti] Título:Working hours associated with unintentional sleep at work among airline pilots.
[So] Source:Rev Saude Publica;51:61, 2017 Jun 26.
[Is] ISSN:1518-8787
[Cp] País de publicação:Brazil
[La] Idioma:eng; por
[Ab] Resumo:OBJECTIVE: Tto identify factors associated with unintentional sleep at work of airline pilots. METHODS: This is a cross-sectional epidemiological study conducted with 1,235 Brazilian airline pilots, who work national or international flights. Data collection has been performed online. We carried out a bivariate and multiple logistic regression analysis, having as dependent variable unintentional sleep at work. The independent variables were related to biodemographic data, characteristics of the work, lifestyle, and aspects of sleep. RESULTS: The prevalence of unintentional sleep while flying the airplane was 57.8%. The factors associated with unintentional sleep at work were: flying for more than 65 hours a month, frequent technical delays, greater need for recovery after work, work ability below optimal, insufficient sleep, and excessive sleepiness. CONCLUSIONS: The occurrence of unintentional sleep at work of airline pilots is associated with factors related to the organization of the work and health. OBJETIVO: Identificar fatores associados aos cochilos não intencionais durante as jornadas de trabalho de pilotos da aviação regular. MÉTODOS: Estudo epidemiológico transversal conduzido com 1.235 pilotos brasileiros de avião do transporte aéreo regular, que realizavam voos nacionais ou internacionais, sendo a coleta de dados realizada on-line. Foi realizada análise de regressão logística bivariada e múltipla, tendo como variável dependente o cochilo não intencional durante o horário de trabalho. As variáveis independentes foram relacionadas a dados biodemográficos, características do trabalho, estilo de vida e aspectos do sono. RESULTADOS: A prevalência do cochilo não intencional enquanto pilotava o avião foi de 57,8%. Os fatores associados ao cochilo não intencional foram: voar por mais de 65 horas por mês, atrasos técnicos frequentes, maior necessidade de recuperação após o trabalho, capacidade para o trabalho inferior à ótima, sono insuficiente e sonolência excessiva. CONCLUSÕES: A ocorrência do cochilo não intencional durante a jornada de trabalho de pilotos da aviação regular está associada a fatores relacionados à organização do trabalho e à saúde.
[Mh] Termos MeSH primário: Pilotos/estatística & dados numéricos
Transtornos do Sono do Ritmo Circadiano/epidemiologia
Transtornos do Sono do Ritmo Circadiano/etiologia
Tolerância ao Trabalho Programado
[Mh] Termos MeSH secundário: Adulto
Aviação/estatística & dados numéricos
Brasil/epidemiologia
Estudos Transversais
Feminino
Seres Humanos
Masculino
Saúde do Trabalhador
Fatores de Risco
Fatores Socioeconômicos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170807
[Lr] Data última revisão:
170807
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170706
[St] Status:MEDLINE


  10 / 1633 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28630378
[Au] Autor:Sletten TL; Ftouni S; Nicholas CL; Magee M; Grunstein RR; Ferguson S; Kennaway DJ; O'Brien D; Lockley SW; Rajaratnam SMW
[Ad] Endereço:Monash Institute of Cognitive and Clinical Neurosciences and School of Psychological Sciences, Monash University, Melbourne, Victoria, Australia.
[Ti] Título:Randomised controlled trial of the efficacy of a blue-enriched light intervention to improve alertness and performance in night shift workers.
[So] Source:Occup Environ Med;74(11):792-801, 2017 Nov.
[Is] ISSN:1470-7926
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: Night workers often experience high levels of sleepiness due to misalignment of the sleep-wake cycle from the circadian pacemaker, in addition to acute and chronic sleep loss. Exposure to light, in particular short wavelength light, can improve alertness and neurobehavioural performance. This randomised controlled trial examined the efficacy of blue-enriched polychromatic light to improve alertness and neurobehavioural performance in night workers. DESIGN: Participants were 71 night shift workers (42 males; 32.8±10.5 years) who worked at least 6 hours between 22:00 and 08:00 hours. Sleep-wake logs and wrist actigraphy were collected for 1-3 weeks, followed by 48-hour urine collection to measure the circadian 6-sulphatoxymelatonin (aMT6s) rhythm. On the night following at least two consecutive night shifts, workers attended a simulated night shift in the laboratory which included subjective and objective assessments of sleepiness and performance. Workers were randomly assigned for exposure to one of two treatment conditions from 23:00 hours to 07:00 hours: blue-enriched white light (17 000 K, 89 lux; n=36) or standard white light (4000 K, 84 lux; n=35). RESULTS: Subjective and objective sleepiness increased during the night shift in both light conditions (p<0.05, η =0.06-0.31), but no significant effects of light condition were observed. The 17 000 K light, however, did improve subjective sleepiness relative to the 4000 K condition when light exposure coincided with the time of the aMT6s peak (p<0.05, d=0.41-0.60). CONCLUSION: This study suggests that, while blue-enriched light has potential to improve subjective sleepiness in night shift workers, further research is needed in the selection of light properties to maximise the benefits. TRIAL REGISTRATION NUMBER: The Australian New Zealand Clinical Trials Registry ACTRN12610000097044 (https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=320845&isReview=true).
[Mh] Termos MeSH primário: Atenção
Ritmo Circadiano
Luz
Transtornos do Sono do Ritmo Circadiano/prevenção & controle
Sono
Vigília
Tolerância ao Trabalho Programado
[Mh] Termos MeSH secundário: Adulto
Feminino
Seres Humanos
Masculino
Melatonina/análogos & derivados
Melatonina/urina
Resultado do Tratamento
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
2208-40-4 (6-sulfatoxymelatonin); JL5DK93RCL (Melatonin)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171102
[Lr] Data última revisão:
171102
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170621
[St] Status:MEDLINE
[do] DOI:10.1136/oemed-2016-103818



página 1 de 164 ir para página                         
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde