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[PMID]:29236818
[Au] Autor:Ortiz KZ; Mantovani-Nagaoka J
[Ad] Endereço:Universidade Federal de São Paulo, Departamento de Fonoaudiologia, São Paulo SP, Brasil.
[Ti] Título:Limb apraxia in aphasic patients.
[So] Source:Arq Neuropsiquiatr;75(11):767-772, 2017 Nov.
[Is] ISSN:1678-4227
[Cp] País de publicação:Brazil
[La] Idioma:eng
[Ab] Resumo:Limb apraxia is usually associated with left cerebral hemisphere damage, with numerous case studies involving aphasic patients. The aim of this study was to verify the occurrence of limb apraxia in aphasic patients and analyze its nature. This study involved 44 healthy volunteers and 28 aphasic patients matched for age and education. AH participants were assessed using a limb apraxia battery comprising subtests evaluating lexical-semantic aspects related to the comprehension/production of gestures as well as motor movements. Aphasics had worse performances on many tasks related to conceptual components of gestures. The difficulty found on the imitation of dynamic gesture tasks also indicated that there were specific motor difficulties in gesture planning. These results reinforce the importance of conducting limb apraxia assessment in aphasic patients and also highlight pantomime difficulties as a good predictor for semantic disturbances.
[Mh] Termos MeSH primário: Afasia/etiologia
Apraxias/etiologia
Acidente Vascular Cerebral/complicações
[Mh] Termos MeSH secundário: Afasia/diagnóstico por imagem
Apraxias/diagnóstico por imagem
Estudos de Casos e Controles
Feminino
Lateralidade Funcional
Seres Humanos
Imagem por Ressonância Magnética
Masculino
Meia-Idade
Testes Neuropsicológicos
Fatores Socioeconômicos
Acidente Vascular Cerebral/diagnóstico por imagem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180129
[Lr] Data última revisão:
180129
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171214
[St] Status:MEDLINE


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[PMID]:28766954
[Au] Autor:Mezzedimi C; Livi W; De Felice C; Cocca S
[Ad] Endereço:1 Department of Medicine, Surgery and Neuroscience, ENT Clinic, University Hospital of Siena, Viale Bracci 14, 53100 Siena, Italy.
[Ti] Título:Dysphagia in Rett Syndrome: A Descriptive Study.
[So] Source:Ann Otol Rhinol Laryngol;126(9):640-645, 2017 Sep.
[Is] ISSN:1943-572X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: Rett syndrome (RS) is a neurodevelopmental disorder and the second major cause of mental retardation in females. The aim of this study was to evaluate swallowing problems of RS patients by endoscopic assessment and compile a list of suggestions for managing feeding and preventing complications. METHODS: The sample consisted of 61 female patients (mean age = 13.6 years, range, 2-33 years) admitted to the Department of Neuropsychiatry, where they had previously been diagnosed with RS. Speech evaluation associated with observation during mealtimes was useful to formulate suggestions for caregivers. RESULTS: Progressive deterioration of feeding was commonly noted by caregivers. Fifty-four patients had a history of recurrent episodes of bronchitis. Oral apraxia, dyskinetic tongue movements, prolonged oral stage, and poor bolus formation were the most common findings in all patients. CONCLUSIONS: Dysphagia was primarily limited to oral preparatory phases, while the pharyngeal phase was normal in most patients. The high percentage of dysphagia suggests the need to accurately monitor the feeding capability of RS children. It is critical to correctly inform caregivers about safe swallowing procedures to reduce the incidence of fatal complications.
[Mh] Termos MeSH primário: Apraxias/fisiopatologia
Transtornos de Deglutição/fisiopatologia
Discinesias/fisiopatologia
Síndrome de Rett/fisiopatologia
Língua/fisiopatologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Apraxias/complicações
Criança
Pré-Escolar
Deglutição
Transtornos de Deglutição/etiologia
Discinesias/complicações
Feminino
Seres Humanos
Faringe/fisiopatologia
Síndrome de Rett/complicações
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170821
[Lr] Data última revisão:
170821
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170803
[St] Status:MEDLINE
[do] DOI:10.1177/0003489417723033


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[PMID]:28427970
[Au] Autor:Freyschlag CF; Kerschbaumer J; Pinggera D; Bacher G; Mur E; Thomé C
[Ad] Endereço:Department of Neurosurgery, Medical University of Innsbruck, Innsbruck, Austria. Electronic address: christian.freyschlag@i-med.ac.at.
[Ti] Título:Structured Evaluation of Glioma Patients by an Occupational Therapist-Is Our Clinical Examination Enough?
[So] Source:World Neurosurg;103:493-500, 2017 Jul.
[Is] ISSN:1878-8769
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Preservation of neurologic function is mandatory when offering a surgical intervention to patients with low-grade gliomas (LGGs), given that the goal of any treatment is the patient's return to their normal everyday life. OBJECTIVE: To determine whether a structured evaluation by an occupational therapist can reveal deficits that might be overseen in routine clinical examination of patients with a surgically treated LGG. METHODS: A total of 20 patients with radiographically suspected LGG were examined in a standardized fashion at 3 stages: preoperatively, postoperatively, and 3 months thereafter. Results were analyzed descriptively. RESULTS: A total of 19 patients (95%) showed no postoperative motor deficit; one suffered from akinesia due to supplementary motor area involvement and demonstrated a transient deficit with manifestation on the first postoperative day. Patients with eloquent LGGs, involving speech (n = 6, 30%), exhibited different transient speech disturbances according to the location of the lesion. Structured testing revealed a postoperative worsening of movement mirroring (upper extremity) and finger discrimination (sensory) in 5 of 20 patients (25%). Force meter evaluation of the upper extremity was decreased significantly postoperatively for the affected hemisphere, even though motor deficits were absent in most patients. The action research arm test detected deterioration in more than one half of the patients postoperatively. Patients recovered from these deficits within the first 3 months. CONCLUSIONS: Routine clinical examination and neuropsychological evaluation fail to detect mild deficits in sensory function, reactivity, and apraxia, which may have a serious impact on patients' ability to return to their normal lives and work.
[Mh] Termos MeSH primário: Apraxias/fisiopatologia
Neoplasias Encefálicas/fisiopatologia
Glioma/fisiopatologia
Transtornos dos Movimentos/fisiopatologia
Exame Neurológico
Neurocirurgiões
Terapeutas Ocupacionais
Distúrbios da Fala/fisiopatologia
[Mh] Termos MeSH secundário: Adulto
Idoso
Apraxias/diagnóstico
Apraxias/etiologia
Mapeamento Encefálico
Neoplasias Encefálicas/diagnóstico por imagem
Neoplasias Encefálicas/patologia
Neoplasias Encefálicas/cirurgia
Função Executiva
Feminino
Neuroimagem Funcional
Glioma/diagnóstico por imagem
Glioma/patologia
Glioma/cirurgia
Seres Humanos
Monitorização Neurofisiológica Intraoperatória
Imagem por Ressonância Magnética
Masculino
Meia-Idade
Transtornos dos Movimentos/diagnóstico
Transtornos dos Movimentos/etiologia
Força Muscular
Gradação de Tumores
Testes Neuropsicológicos
Procedimentos Neurocirúrgicos
Exame Físico
Estudos Prospectivos
Distúrbios da Fala/diagnóstico
Distúrbios da Fala/etiologia
Estereognose
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; OBSERVATIONAL STUDY
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170925
[Lr] Data última revisão:
170925
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170422
[St] Status:MEDLINE


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[PMID]:28384803
[Au] Autor:Shriberg LD; Strand EA; Fourakis M; Jakielski KJ; Hall SD; Karlsson HB; Mabie HL; McSweeny JL; Tilkens CM; Wilson DL
[Ad] Endereço:Waisman Center, University of Wisconsin-Madison.
[Ti] Título:A Diagnostic Marker to Discriminate Childhood Apraxia of Speech From Speech Delay: II. Validity Studies of the Pause Marker.
[So] Source:J Speech Lang Hear Res;60(4):S1118-S1134, 2017 04 14.
[Is] ISSN:1558-9102
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Purpose: The purpose of this 2nd article in this supplement is to report validity support findings for the Pause Marker (PM), a proposed single-sign diagnostic marker of childhood apraxia of speech (CAS). Method: PM scores and additional perceptual and acoustic measures were obtained from 296 participants in cohorts with idiopathic and neurogenetic CAS, adult-onset apraxia of speech and primary progressive apraxia of speech, and idiopathic speech delay. Results: Adjusted for questionable specificity disagreements with a pediatric Mayo Clinic diagnostic standard, the estimated sensitivity and specificity, respectively, of the PM were 86.8% and 100% for the CAS cohort, yielding positive and negative likelihood ratios of 56.45 (95% confidence interval [CI]: [1.15, 2763.31]) and 0.13 (95% CI [0.06, 0.30]). Specificity of the PM for 4 cohorts totaling 205 participants with speech delay was 98.5%. Conclusion: These findings are interpreted as providing support for the PM as a near-conclusive diagnostic marker of CAS.
[Mh] Termos MeSH primário: Apraxias/diagnóstico
Transtornos do Desenvolvimento da Linguagem/diagnóstico
[Mh] Termos MeSH secundário: Adolescente
Idade de Início
Idoso
Idoso de 80 Anos ou mais
Apraxias/classificação
Apraxias/etiologia
Criança
Pré-Escolar
Estudos de Coortes
Diagnóstico Diferencial
Feminino
Seres Humanos
Transtornos do Desenvolvimento da Linguagem/classificação
Testes de Linguagem
Masculino
Meia-Idade
Sensibilidade e Especificidade
Acústica da Fala
Testes de Articulação da Fala
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; VALIDATION STUDIES; RESEARCH SUPPORT, N.I.H., EXTRAMURAL
[Em] Mês de entrada:1707
[Cu] Atualização por classe:171113
[Lr] Data última revisão:
171113
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170407
[St] Status:MEDLINE
[do] DOI:10.1044/2016_JSLHR-S-15-0297


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[PMID]:28384779
[Au] Autor:Shriberg LD; Strand EA; Fourakis M; Jakielski KJ; Hall SD; Karlsson HB; Mabie HL; McSweeny JL; Tilkens CM; Wilson DL
[Ad] Endereço:Waisman Center, University of Wisconsin-Madison.
[Ti] Título:A Diagnostic Marker to Discriminate Childhood Apraxia of Speech From Speech Delay: I. Development and Description of the Pause Marker.
[So] Source:J Speech Lang Hear Res;60(4):S1096-S1117, 2017 04 14.
[Is] ISSN:1558-9102
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Purpose: The goal of this article (PM I) is to describe the rationale for and development of the Pause Marker (PM), a single-sign diagnostic marker proposed to discriminate early or persistent childhood apraxia of speech from speech delay. Method: The authors describe and prioritize 7 criteria with which to evaluate the research and clinical utility of a diagnostic marker for childhood apraxia of speech, including evaluation of the present proposal. An overview is given of the Speech Disorders Classification System, including extensions completed in the same approximately 3-year period in which the PM was developed. Results: The finalized Speech Disorders Classification System includes a nosology and cross-classification procedures for childhood and persistent speech disorders and motor speech disorders (Shriberg, Strand, & Mabie, 2017). A PM is developed that provides procedural and scoring information, and citations to papers and technical reports that include audio exemplars of the PM and reference data used to standardize PM scores are provided. Conclusions: The PM described here is an acoustic-aided perceptual sign that quantifies one aspect of speech precision in the linguistic domain of phrasing. This diagnostic marker can be used to discriminate early or persistent childhood apraxia of speech from speech delay.
[Mh] Termos MeSH primário: Apraxias/diagnóstico
Transtornos do Desenvolvimento da Linguagem/diagnóstico
[Mh] Termos MeSH secundário: Apraxias/classificação
Criança
Diagnóstico Diferencial
Seres Humanos
Transtornos do Desenvolvimento da Linguagem/classificação
Linguística
Reprodutibilidade dos Testes
Acústica da Fala
Testes de Articulação da Fala
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW; RESEARCH SUPPORT, N.I.H., EXTRAMURAL
[Em] Mês de entrada:1707
[Cu] Atualização por classe:171113
[Lr] Data última revisão:
171113
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170407
[St] Status:MEDLINE
[do] DOI:10.1044/2016_JSLHR-S-15-0296


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[PMID]:28384751
[Au] Autor:Shriberg LD; Strand EA; Fourakis M; Jakielski KJ; Hall SD; Karlsson HB; Mabie HL; McSweeny JL; Tilkens CM; Wilson DL
[Ad] Endereço:Waisman Center, University of Wisconsin-Madison.
[Ti] Título:A Diagnostic Marker to Discriminate Childhood Apraxia of Speech From Speech Delay: III. Theoretical Coherence of the Pause Marker with Speech Processing Deficits in Childhood Apraxia of Speech.
[So] Source:J Speech Lang Hear Res;60(4):S1135-S1152, 2017 04 14.
[Is] ISSN:1558-9102
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Purpose: Previous articles in this supplement described rationale for and development of the pause marker (PM), a diagnostic marker of childhood apraxia of speech (CAS), and studies supporting its validity and reliability. The present article assesses the theoretical coherence of the PM with speech processing deficits in CAS. Method: PM and other scores were obtained for 264 participants in 6 groups: CAS in idiopathic, neurogenetic, and complex neurodevelopmental disorders; adult-onset apraxia of speech (AAS) consequent to stroke and primary progressive apraxia of speech; and idiopathic speech delay. Results: Participants with CAS and AAS had significantly lower scores than typically speaking reference participants and speech delay controls on measures posited to assess representational and transcoding processes. Representational deficits differed between CAS and AAS groups, with support for both underspecified linguistic representations and memory/access deficits in CAS, but for only the latter in AAS. CAS-AAS similarities in the age-sex standardized percentages of occurrence of the most frequent type of inappropriate pauses (abrupt) and significant differences in the standardized occurrence of appropriate pauses were consistent with speech processing findings. Conclusions: Results support the hypotheses of core representational and transcoding speech processing deficits in CAS and theoretical coherence of the PM's pause-speech elements with these deficits.
[Mh] Termos MeSH primário: Apraxias/diagnóstico
Transtornos do Desenvolvimento da Linguagem/diagnóstico
Modelos Teóricos
Percepção da Fala
Fala
[Mh] Termos MeSH secundário: Adolescente
Idoso
Idoso de 80 Anos ou mais
Apraxias/etiologia
Criança
Pré-Escolar
Diagnóstico Diferencial
Feminino
Seres Humanos
Testes de Linguagem
Masculino
Meia-Idade
Testes de Articulação da Fala
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL
[Em] Mês de entrada:1707
[Cu] Atualização por classe:171113
[Lr] Data última revisão:
171113
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170407
[St] Status:MEDLINE
[do] DOI:10.1044/2016_JSLHR-S-15-0298


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[PMID]:28384695
[Au] Autor:Shriberg LD; Strand EA; Fourakis M; Jakielski KJ; Hall SD; Karlsson HB; Mabie HL; McSweeny JL; Tilkens CM; Wilson DL
[Ad] Endereço:Waisman Center, University of Wisconsin-Madison.
[Ti] Título:A Diagnostic Marker to Discriminate Childhood Apraxia of Speech From Speech Delay: Introduction.
[So] Source:J Speech Lang Hear Res;60(4):S1094-S1095, 2017 04 14.
[Is] ISSN:1558-9102
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Purpose: The goal of this article is to introduce the pause marker (PM), a single-sign diagnostic marker proposed to discriminate early or persistent childhood apraxia of speech (CAS) from speech delay.
[Mh] Termos MeSH primário: Apraxias/diagnóstico
Transtornos do Desenvolvimento da Linguagem/diagnóstico
[Mh] Termos MeSH secundário: Criança
Diagnóstico Diferencial
Seres Humanos
[Pt] Tipo de publicação:INTRODUCTORY JOURNAL ARTICLE
[Em] Mês de entrada:1707
[Cu] Atualização por classe:171113
[Lr] Data última revisão:
171113
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170407
[St] Status:MEDLINE
[do] DOI:10.1044/2016_JSLHR-S-16-0148


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[PMID]:28384662
[Au] Autor:Shriberg LD; Strand EA; Fourakis M; Jakielski KJ; Hall SD; Karlsson HB; Mabie HL; McSweeny JL; Tilkens CM; Wilson DL
[Ad] Endereço:Waisman Center, University of Wisconsin-Madison.
[Ti] Título:A Diagnostic Marker to Discriminate Childhood Apraxia of Speech From Speech Delay: IV. The Pause Marker Index.
[So] Source:J Speech Lang Hear Res;60(4):S1153-S1169, 2017 04 14.
[Is] ISSN:1558-9102
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Purpose: Three previous articles provided rationale, methods, and several forms of validity support for a diagnostic marker of childhood apraxia of speech (CAS), termed the pause marker (PM). Goals of the present article were to assess the validity and stability of the PM Index (PMI) to scale CAS severity. Method: PM scores and speech, prosody, and voice precision-stability data were obtained for participants with CAS in idiopathic, neurogenetic, and complex neurodevelopmental disorders; adult-onset apraxia of speech consequent to stroke and primary progressive apraxia; and idiopathic speech delay. Three studies were completed including criterion and concurrent validity studies of the PMI and a temporal stability study of the PMI using retrospective case studies. Results: PM scores were significantly correlated with other signs of CAS precision and stability. The best fit of the distribution of PM scores to index CAS severity was obtained by dividing scores into 4 ordinal severity classifications: mild, mild-moderate, moderate-severe, and severe. Severity findings for the 4 classifications and retrospective longitudinal findings from 8 participants with CAS supported the validity and stability of the PMI. Conclusion: Findings support research and clinical use of the PMI to scale the severity of CAS.
[Mh] Termos MeSH primário: Apraxias/classificação
Apraxias/diagnóstico
Transtornos do Desenvolvimento da Linguagem/diagnóstico
Índice de Gravidade de Doença
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idade de Início
Idoso
Idoso de 80 Anos ou mais
Apraxias/etiologia
Criança
Pré-Escolar
Diagnóstico Diferencial
Feminino
Seres Humanos
Transtornos do Desenvolvimento da Linguagem/classificação
Estudos Longitudinais
Masculino
Meia-Idade
Estudos Retrospectivos
Fala
Medida da Produção da Fala
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; VALIDATION STUDIES; RESEARCH SUPPORT, N.I.H., EXTRAMURAL
[Em] Mês de entrada:1707
[Cu] Atualização por classe:171113
[Lr] Data última revisão:
171113
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170407
[St] Status:MEDLINE
[do] DOI:10.1044/2016_JSLHR-S-16-0149


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[PMID]:28345801
[Au] Autor:Zanzottera C; Milani D; Alfei E; Rizzo A; D'Arrigo S; Esposito S; Pantaleoni C
[Ad] Endereço:Clinical Genetics Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
[Ti] Título:ZC4H2 deletions can cause severe phenotype in female carriers.
[So] Source:Am J Med Genet A;173(5):1358-1363, 2017 May.
[Is] ISSN:1552-4833
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:ZC4H2 is involved in human brain development, and, if mutated, can be responsible for a rare X-linked disorder, originally presented in literature as Wieacker-Wolff syndrome and Miles-Carpenter syndrome. In males, severe intellectual disability is associated with variable symptoms of central and peripheral nervous system involvement, such as spasticity, hyperreflexia, muscle weakness, and arthrogryposis. Female carriers are usually described as asymptomatic or only mildly affected. Here, we report on a girl carrying a de novo deletion of ZC4H2 detected by array-CGH analysis. She showed a complex neurodevelopmental disorder resembling the clinical picture commonly observed in male patients. X-inactivation was found to be random. Additionally, she had an unusual appearance of fingers and hand creases, and electromyography showed a peculiar pattern of both neurogenic and myopathic anomalies. The present patient confirms that female carriers can also be severely affected. Systematic clinical investigations of both males and females are needed to define the variety in nature and severity of phenotypes related to ZC4H2 variants.
[Mh] Termos MeSH primário: Apraxias/genética
Proteínas de Transporte/genética
Contratura/genética
Doenças Genéticas Ligadas ao Cromossomo X/genética
Deficiência Intelectual/genética
Retardo Mental Ligado ao Cromossomo X/genética
Retardo Mental Ligado ao Cromossomo X/psicologia
Atrofia Muscular/genética
Oftalmoplegia/genética
[Mh] Termos MeSH secundário: Adolescente
Apraxias/diagnóstico
Apraxias/fisiopatologia
Criança
Hibridização Genômica Comparativa
Contratura/diagnóstico
Contratura/fisiopatologia
Feminino
Doenças Genéticas Ligadas ao Cromossomo X/diagnóstico
Doenças Genéticas Ligadas ao Cromossomo X/fisiopatologia
Seres Humanos
Deficiência Intelectual/diagnóstico
Deficiência Intelectual/fisiopatologia
Masculino
Retardo Mental Ligado ao Cromossomo X/diagnóstico
Retardo Mental Ligado ao Cromossomo X/fisiopatologia
Atrofia Muscular/diagnóstico
Atrofia Muscular/fisiopatologia
Oftalmoplegia/diagnóstico
Oftalmoplegia/fisiopatologia
Deleção de Sequência
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Carrier Proteins); 0 (ZC4H2 protein, human)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170508
[Lr] Data última revisão:
170508
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170328
[St] Status:MEDLINE
[do] DOI:10.1002/ajmg.a.38155


  10 / 2406 MEDLINE  
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[PMID]:28314241
[Au] Autor:Hagedorn C; Proctor M; Goldstein L; Wilson SM; Miller B; Gorno-Tempini ML; Narayanan SS
[Ad] Endereço:University of Southern California, Los Angeles.
[Ti] Título:Characterizing Articulation in Apraxic Speech Using Real-Time Magnetic Resonance Imaging.
[So] Source:J Speech Lang Hear Res;60(4):877-891, 2017 04 14.
[Is] ISSN:1558-9102
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Purpose: Real-time magnetic resonance imaging (MRI) and accompanying analytical methods are shown to capture and quantify salient aspects of apraxic speech, substantiating and expanding upon evidence provided by clinical observation and acoustic and kinematic data. Analysis of apraxic speech errors within a dynamic systems framework is provided and the nature of pathomechanisms of apraxic speech discussed. Method: One adult male speaker with apraxia of speech was imaged using real-time MRI while producing spontaneous speech, repeated naming tasks, and self-paced repetition of word pairs designed to elicit speech errors. Articulatory data were analyzed, and speech errors were detected using time series reflecting articulatory activity in regions of interest. Results: Real-time MRI captured two types of apraxic gestural intrusion errors in a word pair repetition task. Gestural intrusion errors in nonrepetitive speech, multiple silent initiation gestures at the onset of speech, and covert (unphonated) articulation of entire monosyllabic words were also captured. Conclusion: Real-time MRI and accompanying analytical methods capture and quantify many features of apraxic speech that have been previously observed using other modalities while offering high spatial resolution. This patient's apraxia of speech affected the ability to select only the appropriate vocal tract gestures for a target utterance, suppressing others, and to coordinate them in time.
[Mh] Termos MeSH primário: Apraxias/diagnóstico por imagem
Imagem por Ressonância Magnética/métodos
Boca/diagnóstico por imagem
Medida da Produção da Fala/métodos
Fala
[Mh] Termos MeSH secundário: Encéfalo/diagnóstico por imagem
Gestos
Seres Humanos
Processamento de Imagem Assistida por Computador
Masculino
Entrevista Psiquiátrica Padronizada
Meia-Idade
Destreza Motora
Projetos Piloto
Afasia Primária Progressiva não Fluente/diagnóstico por imagem
Espectrografia do Som
Fatores de Tempo
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL
[Em] Mês de entrada:1707
[Cu] Atualização por classe:171113
[Lr] Data última revisão:
171113
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170318
[St] Status:MEDLINE
[do] DOI:10.1044/2016_JSLHR-S-15-0112



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