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[PMID]:29292957
[Au] Autor:Bjerin O; Martín Muñoz D; Gerald C; Brytting M; Eriksson M
[Ad] Endereço:Karolinska sjukhuset - Solna, Sweden - pediatric neurology Solna, Sweden.
[Ti] Título:Misstänkt koppling mellan enterovirus D68 och akut slapp myelit hos svenska barn - Ansamling av fall under några veckor hösten 2016..
[So] Source:Lakartidningen;114, 2017 Nov 30.
[Is] ISSN:1652-7518
[Cp] País de publicação:Sweden
[La] Idioma:swe
[Ab] Resumo:Acute flaccid myelitis amongst Swedish children with a possible link to an outbreak of enterovirus D68 In september 2016 we had several cases of acute flaccid myelitis in our clinic. This coincided with an outbreak of enterovirus D68 (EV-D68) in Sweden during the same period. We describe three cases, of which one tested positive for EV-D68. Acute flaccid paralysis of one or more limbs preceded by an upper respiratory tract infection is highly suspicious of myelitis, and a viral cause must be included in the clinical work-up. In order to detect infection with EV-D68 in suspected acute flaccid myelitis, nasopharyngeal aspirate should be performed as early as possible. EV-D68 is normally not found in stool or cerebrospinal fluid tests but should be included in the clinical work-up. Treatment of acute flaccid myelitis is supportive only. There is no effective antiviral treatment and immunomodulating therapies show little effect. Persisting neurological deficits are common but lethal cases are rare.
[Mh] Termos MeSH primário: Infecções por Enterovirus/complicações
Mielite/virologia
Paralisia/virologia
[Mh] Termos MeSH secundário: Doença Aguda
Criança
Pré-Escolar
Surtos de Doenças
Enterovirus Humano D/isolamento & purificação
Infecções por Enterovirus/epidemiologia
Infecções por Enterovirus/terapia
Feminino
Seres Humanos
Imagem por Ressonância Magnética
Masculino
Mielite/diagnóstico por imagem
Mielite/epidemiologia
Mielite/terapia
Paralisia/epidemiologia
Paralisia/terapia
Suécia/epidemiologia
[Pt] Tipo de publicação:CASE REPORTS
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180306
[Lr] Data última revisão:
180306
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180103
[St] Status:MEDLINE


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[PMID]:29197328
[Au] Autor:Wang HB; Luo HM; Li L; Fan CX; Hao LX; Ma C; Su QR; Yang H; Reilly KH; Wang HQ; Wen N
[Ad] Endereço:Chinese Center for Disease Control and Prevention, 27 Nanwei Road, Beijing, 100050, People's Republic of China.
[Ti] Título:Vaccine-derived poliovirus surveillance in China during 2001-2013: the potential challenge for maintaining polio free status.
[So] Source:BMC Infect Dis;17(1):742, 2017 12 02.
[Is] ISSN:1471-2334
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The goal of polio eradication is to complete elimination and containment of all wild, vaccine-related and Sabin polioviruses. Vaccine-derived poliovirus (VDPV) surveillance in China from 2001-2013 is summarized in this report, which has important implications for the global polio eradication initiative. METHODS: Acute flaccid paralysis (AFP) cases and their contacts with VDPVs isolated from fecal specimens were identified in our AFP surveillance system or by field investigation. Epidemiological and laboratory information for these children were analyzed and the reasons for the VDPV outbreak was explored. RESULTS: VDPVs were isolated from a total of 49 children in more than two-thirds of Chinese provinces from 2001-2013, including 15 VDPV cases, 15 non-polio AFP cases and 19 contacts of AFP cases or healthy subjects. A total of 3 circulating VDPVs (cVDPVs) outbreaks were reported in China, resulting in 6 cVDPVs cases who had not been vaccinated with oral attenuated poliomyelitis vaccine. Among the 4 immunodeficiency-associated VDPVs (iVDPVs) cases, the longest duration of virus excretion was about 20 months. In addition, one imported VDPV case from Myanmar was detected in Yunnan Province. CONCLUSIONS: Until all wild, vaccine-related and Sabin polioviruses are eradicated in the world, high quality routine immunization and sensitive AFP surveillance should be maintained, focusing efforts on underserved populations in high risk areas.
[Mh] Termos MeSH primário: Erradicação de Doenças
Paralisia/epidemiologia
Paralisia/virologia
Vacinas contra Poliovirus/imunologia
[Mh] Termos MeSH secundário: Anticorpos Antivirais/sangue
Criança
Pré-Escolar
China/epidemiologia
Feminino
Voluntários Saudáveis
Seres Humanos
Lactente
Masculino
Mianmar
Poliomielite/epidemiologia
Poliomielite/prevenção & controle
Poliovirus/imunologia
Vacina Antipólio Oral/uso terapêutico
Vacinas contra Poliovirus/uso terapêutico
Fatores de Tempo
Cobertura Vacinal
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antibodies, Viral); 0 (Poliovirus Vaccine, Oral); 0 (Poliovirus Vaccines)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180305
[Lr] Data última revisão:
180305
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171204
[St] Status:MEDLINE
[do] DOI:10.1186/s12879-017-2849-z


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[PMID]:29390312
[Au] Autor:Jang SH; Lee HD
[Ad] Endereço:Department of Physical Medicine and Rehabilitation, College of Medicine, Yeungnam University, Taegu, Republic of Korea.
[Ti] Título:Gait recovery by activation of the unaffected corticoreticulospinal tract in a stroke patient: A case report.
[So] Source:Medicine (Baltimore);96(50):e9123, 2017 Dec.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:RATIONALE: A 50-year-old man presented with complete paralysis at the onset of a putaminal hemorrhage. PATIENT CONCERNS: The patient presented with complete paralysis of the left upper and lower extremities (Medical Research Council:0/5). DIAGNOSES: Spontaneous intra crebral hemorrhage on putamen. INTERVENTION: He underwent comprehensive rehabilitative therapy from 3 weeks after onset. At 3weeks after onset, he presented with severe weakness of the left extremities. The weakness of his left extremities had recovered as follows at 3 months after onset. Consequently, he was able to walk independently on an even floor. OUTCOMES: On 3-week and 3-month diffusion tensor tractography (DTTs), the right corticospinal tract (CST) and the corticoreticulospinal tract (CRT) showed discontinuations below the lesion. On 3-month DTT, the left CST had become thinner; however, the left CRT had become thicker compared with 3-week DTT (Fig. 1). LESSONS: To the best of our knowledge, this is the first study to demonstrate the activation process of the CRT in the unaffected hemisphere in relation to gait recovery from early to chronic stage of stroke.
[Mh] Termos MeSH primário: Transtornos Neurológicos da Marcha/reabilitação
Paralisia/reabilitação
Hemorragia Putaminal/complicações
[Mh] Termos MeSH secundário: Imagem de Tensor de Difusão
Transtornos Neurológicos da Marcha/etiologia
Seres Humanos
Masculino
Meia-Idade
Paralisia/etiologia
Recuperação de Função Fisiológica
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180301
[Lr] Data última revisão:
180301
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180203
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000009123


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[PMID]:29390549
[Au] Autor:Yasuda T; Kawaguchi Y; Suzuki K; Nakano M; Seki S; Watabnabe K; Kanamori M; Kimura T
[Ad] Endereço:Departments of Orthopaedic Surgery, Faculty of Medicine, University of Toyama.
[Ti] Título:Five-year follow up results of posterior decompression and fixation surgery for delayed neural disorder associated with osteoporotic vertebral fracture.
[So] Source:Medicine (Baltimore);96(51):e9395, 2017 Dec.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Usually, after osteoporotic vertebral fracture (OVF), bone healing follows a normal clinical course leading to bone union with conservative treatment using a brace. However, some patients with OVF do not undergo the normal fracture healing process for a few months, possibly leading to delayed union and/or pseudoarthrosis. In these cases, we performed posterior surgery with combined decompression, vertebroplasty, and posterior spinal fusion with spinal instrumentation. This study aimed to determine the clinical results of posterior surgery for delayed neural disorder secondary to OVF over a 5-year follow-up.Forty-one Japanese patients who had posterior surgery for delayed paralysis secondary to OVF were enrolled in this study. All patients were followed for ≥5 years (mean, 67 months; range, 61-86 months). Patients comprised 12 men and 29 women with an average age of 76.3 ± 6.2 years (range 63-87 years) at the time of operation. We performed posterior fixation from 2 levels above to 1 level below the decompression and vertebroplasty as an all in one procedure. Vertebral height index (VHI) and kyphotic angle (KA) were evaluated on radiogram. For clinical symptoms, a visual analog scale of back and leg pain and the Frankel classification and Japanese Orthopaedic Association scores were used.During the operation and perioperative period, no serious complications occurred. In all patients, symptoms improved within 1 month and were maintained for 5 years postoperatively. In all patients, VHI and KA improved after surgery; however, reduction losses of 7.7% of VHI and 23% of KA were recognized. Five of 41 patients required reoperation due to adjacent vertebral fracture (AVF) and recollapse of the vertebral body.Operation time and blood loss were acceptable, even for elderly patients. In all patients, alignment and subjective symptoms improved. However, reoperation owing to AVF and recollapse was necessary within 1 year in 5 of 41 (12%) patients. Careful follow-up is required within 1 year after surgery for OVF.
[Mh] Termos MeSH primário: Laminectomia/métodos
Fraturas por Osteoporose/complicações
Paralisia/cirurgia
Pseudoartrose/complicações
Fraturas da Coluna Vertebral/complicações
Fusão Vertebral/métodos
[Mh] Termos MeSH secundário: Idoso
Idoso de 80 Anos ou mais
Estudos de Casos e Controles
Feminino
Seguimentos
Seres Humanos
Masculino
Meia-Idade
Fraturas por Osteoporose/cirurgia
Paralisia/etiologia
Pseudoartrose/cirurgia
Fraturas da Coluna Vertebral/cirurgia
Fusão Vertebral/instrumentação
Resultado do Tratamento
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; OBSERVATIONAL STUDY
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180214
[Lr] Data última revisão:
180214
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180203
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000009395


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[PMID]:29326249
[Au] Autor:Roberts L
[Ti] Título:In Pakistan, surveillance for polio reveals a paradox.
[So] Source:Science;359(6372):142-143, 2018 Jan 12.
[Is] ISSN:1095-9203
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Monitoramento Epidemiológico
Poliomielite/epidemiologia
Poliovirus/isolamento & purificação
Esgotos/virologia
[Mh] Termos MeSH secundário: Área Programática (Saúde)
Criança
Pré-Escolar
Erradicação de Doenças
Seres Humanos
Programas de Imunização
Lactente
Paquistão/epidemiologia
Paralisia
Poliomielite/imunologia
Poliomielite/prevenção & controle
Poliovirus/imunologia
Poliovirus/fisiologia
Vacinas contra Poliovirus/administração & dosagem
[Pt] Tipo de publicação:NEWS
[Nm] Nome de substância:
0 (Poliovirus Vaccines); 0 (Sewage)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180207
[Lr] Data última revisão:
180207
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180113
[St] Status:MEDLINE
[do] DOI:10.1126/science.359.6372.142


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[PMID]:29240729
[Au] Autor:Zhao D; Ma R; Zhou T; Yang F; Wu J; Sun H; Liu F; Lu L; Li X; Zuo S; Yao W; Yin J
[Ti] Título:Introduction of Inactivated Poliovirus Vaccine and Impact on Vaccine-Associated Paralytic Poliomyelitis - Beijing, China, 2014-2016.
[So] Source:MMWR Morb Mortal Wkly Rep;66(49):1357-1361, 2017 Dec 15.
[Is] ISSN:1545-861X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:When included in a sequential polio vaccination schedule, inactivated polio vaccine (IPV) reduces the risk for vaccine-associated paralytic poliomyelitis (VAPP), a rare adverse event associated with receipt of oral poliovirus vaccine (OPV). During January 2014, the World Health Organization (WHO) recommended introduction of at least 1 IPV dose into routine immunization schedules in OPV-using countries (1). The Polio Eradication and Endgame Strategic Plan 2013-2018 recommended completion of IPV introduction in 2015 and globally synchronized withdrawal of OPV type 2 in 2016 (2). Introduction of 1 dose of IPV into Beijing's Expanded Program on Immunization (EPI) on December 5, 2014 represented China's first province-wide IPV introduction. Coverage with the first dose of polio vaccine was maintained from 96.2% to 96.9%, similar to coverage with the first dose of diphtheria and tetanus toxoids and pertussis vaccine (DTP) (96.5%-97.2%); the polio vaccine dropout rate (the percentage of children who received the first dose of polio vaccine but failed to complete the series) was 1.0% in 2015 and 0.4% in 2016. The use of 3 doses of private-sector IPV per child decreased from 18.1% in 2014, to 17.4% in 2015, and to 14.8% in 2016. No cases of VAPP were identified during 2014-2016. Successful introduction of IPV into the public sector EPI program was attributed to comprehensive planning, preparation, implementation, robust surveillance for adverse events after immunization (AEFI), and monitoring of vaccination coverage. This evaluation provided information that helped contribute to the expansion of IPV use in China and in other OPV-using countries.
[Mh] Termos MeSH primário: Paralisia/prevenção & controle
Poliomielite/prevenção & controle
Vacina Antipólio de Vírus Inativado/administração & dosagem
[Mh] Termos MeSH secundário: Adolescente
Pequim/epidemiologia
Criança
Pré-Escolar
Seres Humanos
Programas de Imunização
Esquemas de Imunização
Lactente
Paralisia/induzido quimicamente
Paralisia/epidemiologia
Poliomielite/induzido quimicamente
Poliomielite/epidemiologia
Vacina Antipólio Oral/efeitos adversos
Avaliação de Programas e Projetos de Saúde
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Poliovirus Vaccine, Inactivated); 0 (Poliovirus Vaccine, Oral)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:180119
[Lr] Data última revisão:
180119
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171215
[St] Status:MEDLINE
[do] DOI:10.15585/mmwr.mm6649a4


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[PMID]:29244816
[Au] Autor:Avila-Martin G; Mata-Roig M; Galán-Arriero I; Taylor JS; Busquets X; Escribá PV
[Ad] Endereço:Hospital Nacional de Parapléjicos, Toledo, Spain.
[Ti] Título:Treatment with albumin-hydroxyoleic acid complex restores sensorimotor function in rats with spinal cord injury: Efficacy and gene expression regulation.
[So] Source:PLoS One;12(12):e0189151, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Sensorimotor dysfunction following incomplete spinal cord injury (SCI) is often characterized by paralysis, spasticity and pain. Previously, we showed that intrathecal (i.t.) administration of the albumin-oleic acid (A-OA) complex in rats with SCI produced partial improvement of these symptoms and that oral 2-hydroxyoleic acid (HOA, a non-hydrolyzable OA analogue), was efficacious in the modulation and treatment of nociception and pain-related anxiety, respectively. Here we observed that intrathecal treatment with the complex albumin-HOA (A-HOA) every 3 days following T9 spinal contusion injury improved locomotor function assessed with the Rotarod and inhibited TA noxious reflex activity in Wistar rats. To investigate the mechanism of action of A-HOA, microarray analysis was carried out in the spinal cord lesion area. Representative genes involved in pain and neuroregeneration were selected to validate the changes observed in the microarray analysis by quantitative real-time RT-PCR. Comparison of the expression between healthy rats, SCI rats, and SCI treated with A-HOA rats revealed relevant changes in the expression of genes associated with neuronal morphogenesis and growth, neuronal survival, pain and inflammation. Thus, treatment with A-HOA not only induced a significant overexpression of growth and differentiation factor 10 (GDF10), tenascin C (TNC), aspirin (ASPN) and sushi-repeat-containing X-linked 2 (SRPX2), but also a significant reduction in the expression of prostaglandin E synthase (PTGES) and phospholipases A1 and A2 (PLA1/2). Currently, SCI has very important unmet clinical needs. A-HOA downregulated genes involved with inflammation and upregulated genes involved in neuronal growth, and may serve to promote recovery of function after experimental SCI.
[Mh] Termos MeSH primário: Albuminas/farmacologia
Ácidos Oleicos/farmacologia
Dor/prevenção & controle
Paralisia/tratamento farmacológico
Recuperação de Função Fisiológica/efeitos dos fármacos
Traumatismos da Medula Espinal/tratamento farmacológico
[Mh] Termos MeSH secundário: Albuminas/química
Animais
Esquema de Medicação
Proteínas da Matriz Extracelular/agonistas
Proteínas da Matriz Extracelular/genética
Proteínas da Matriz Extracelular/metabolismo
Regulação da Expressão Gênica
Fator 10 de Diferenciação de Crescimento/agonistas
Fator 10 de Diferenciação de Crescimento/genética
Fator 10 de Diferenciação de Crescimento/metabolismo
Injeções Espinhais
Locomoção/efeitos dos fármacos
Locomoção/fisiologia
Masculino
Proteínas do Tecido Nervoso/agonistas
Proteínas do Tecido Nervoso/genética
Proteínas do Tecido Nervoso/metabolismo
Nociceptividade/efeitos dos fármacos
Ácidos Oleicos/química
Dor/genética
Dor/metabolismo
Dor/patologia
Paralisia/genética
Paralisia/metabolismo
Paralisia/patologia
Fosfolipases/antagonistas & inibidores
Fosfolipases/genética
Fosfolipases/metabolismo
Prostaglandina-E Sintases/antagonistas & inibidores
Prostaglandina-E Sintases/genética
Prostaglandina-E Sintases/metabolismo
Ratos
Ratos Wistar
Recuperação de Função Fisiológica/fisiologia
Teste de Desempenho do Rota-Rod
Medula Espinal/efeitos dos fármacos
Medula Espinal/metabolismo
Medula Espinal/patologia
Traumatismos da Medula Espinal/genética
Traumatismos da Medula Espinal/metabolismo
Traumatismos da Medula Espinal/patologia
Tenascina/agonistas
Tenascina/genética
Tenascina/metabolismo
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (2-hydroxyoleic acid); 0 (Albumins); 0 (Extracellular Matrix Proteins); 0 (Gdf10 protein, rat); 0 (Growth Differentiation Factor 10); 0 (Nerve Tissue Proteins); 0 (Oleic Acids); 0 (Tenascin); 0 (asporin protein, rat); EC 3.1.- (Phospholipases); EC 5.3.99.3 (Prostaglandin-E Synthases); EC 5.3.99.3 (Ptges protein, rat)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180108
[Lr] Data última revisão:
180108
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171216
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0189151


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[PMID]:28983396
[Au] Autor:Wassie E; Ademe A; Gallagher K; Braka F; Beyene B; Woyessa AB; Jima D
[Ad] Endereço:World Health Organization, Ethiopia Country Office.
[Ti] Título:Assessment of reporting sites for acute flaccid paralysis surveillance in Ethiopia: implications for planning of active case search visits.
[So] Source:Pan Afr Med J;27(Suppl 2):8, 2017.
[Is] ISSN:1937-8688
[Cp] País de publicação:Uganda
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: The World Health Organization acute flaccid paralysis (AFP) surveillance standards recommend documentation of the role of each potentially reporting site for evidence -based planning and tailoring support for active surveillance visits. This study assessed the contribution of various sites as source and quality of AFP cases reported over a five -year period in Ethiopia. METHODS: We conducted a retrospective analysis of AFP surveillance data collected from 2010-2014 in Ethiopia. Analyses were done using EPI-INFO version 7 for calculating frequencies and proportions, and testing possible associations between reporting sites and key dependent variables. RESULTS: Of the 5,274 AFP cases reported, hospitals and health centers reported 4627 (88%) of the cases. Hospitals in Addis Ababa (53%) and health posts in Benishangul Gumuz (48%) regions have contributed majority of the cases reported. Only 3% of cases were reported by private clinics nationally. The stool adequacy rate for health posts (81%) was lower than the overall national rate of 88% .Cases from health posts are more likely to be reported after 14 days of onset of paralysis, and 62% less likely to be investigated within two days of notification(OR: 1.82, 95% CI OR : 1.41-2.36, p-value <0.0001). Greater proportion (2.4%) of cases reported from health posts were either compatible, VDPV or WPV compared to cases reported by health centers (1.14%) or hospitals (1.4%). CONCLUSION: Though majority of the cases were reported by health centers followed by hospitals ,our findings suggest that all potentially reporting sites should be exhaustively identified, prioritized and regularly supported for quality case detection, investigation and reporting.
[Mh] Termos MeSH primário: Notificação de Doenças/estatística & dados numéricos
Paralisia/epidemiologia
Poliomielite/epidemiologia
Vigilância da População/métodos
[Mh] Termos MeSH secundário: Etiópia/epidemiologia
Medicina Baseada em Evidências/métodos
Fezes
Seres Humanos
Estudos Retrospectivos
Fatores de Tempo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171030
[Lr] Data última revisão:
171030
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171007
[St] Status:MEDLINE
[do] DOI:10.11604/pamj.supp.2017.27.2.10731


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[PMID]:28983394
[Au] Autor:Lakew GA; Wassie E; Ademe A; Fenta A; Wube S; Werede M; Kidane A; Mekonnen L; Hiwot TG; Gallagher K
[Ad] Endereço:World Health Organization, Ethiopia.
[Ti] Título:Status of surveillance and routine immunization performances in Amhara Region, Ethiopia: findings from in-depth peer review.
[So] Source:Pan Afr Med J;27(Suppl 2):6, 2017.
[Is] ISSN:1937-8688
[Cp] País de publicação:Uganda
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: Trend analyses of non-polio AFP and stool adequacy rates in Amhara Region showed optimal performance over the years. However, sub regional gaps continue to persist in certain zones where the reasons for low performance were not well documented. The objective of this study was to assess the performance of the disease surveillance and immunization system in Amhara Region, Ethiopia with emphasis on low performing woredas and zones. METHODS: A descriptive cross-sectional study was conducted from July 2-10, 2015 to assess the structure, core and support surveillance functions in five zones and two town administrations that were purposively sampled based on differing performances, geographic location, and history of vaccine preventable disease outbreaks among others. RESULTS: Of the 82 sites reviewed, 71 (87%) have a designated surveillance focal person. Less than half 36(44%) of these focal persons have written terms of reference. Twenty-six (93%) of the health offices had a written surveillance work plan for the fiscal year. Only 17 (81%) of woreda health offices and town administrations had prioritized active surveillance sites into high, medium and low during the last 12 months. Only 4(17%) had independent active case search visits to these sites as per the priority. Seventy-eight (95%) and seventy-seven (94%) sites have a designated immunization focal person and updated EPI performance monitoring charts, respectively. There had been vaccine stock out in the 3 months before assessment in 28 (34%) of the sites. CONCLUSION: Though there is an existence of well-organized surveillance network with adoption of the integrated disease surveillance and response, gaps exist in following the standard guidelines and operation procedures. Improvements needed in reporting site priority setting and regular visiting for active case search, outbreak investigation and management, vaccine supply and overall documentations.
[Mh] Termos MeSH primário: Imunização/estatística & dados numéricos
Paralisia/epidemiologia
Vigilância da População/métodos
Vacinas/administração & dosagem
[Mh] Termos MeSH secundário: Estudos Transversais
Surtos de Doenças/prevenção & controle
Etiópia/epidemiologia
Fezes
Seres Humanos
Paralisia/diagnóstico
Paralisia/prevenção & controle
Poliomielite/prevenção & controle
Fatores de Tempo
Vacinas/provisão & distribuição
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Vaccines)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171030
[Lr] Data última revisão:
171030
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171007
[St] Status:MEDLINE
[do] DOI:10.11604/pamj.supp.2017.27.2.10755


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[PMID]:28983391
[Au] Autor:Tegegne AA; Mersha AM
[Ad] Endereço:World Health Organization Country Office, Addis Ababa, Ethiopia.
[Ti] Título:Health care seeking behavior of parents with acute flaccid paralysis child.
[So] Source:Pan Afr Med J;27(Suppl 2):3, 2017.
[Is] ISSN:1937-8688
[Cp] País de publicação:Uganda
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: Despite the tremendous increase in the number of modern health institutions, traditional medical practices still remain alternative places of health care service delivery and important sites for disease notification in the disease surveillance system. The objectives of this study are to describe the patterns and factors associated with health care seeking behavior of parents and care takers with acute flaccid paralysis child and see how the traditional practice affect the surveillance system. METHODS: A cross-sectional descriptive study was conducted to assess the health seeking behavior of parents with an acute flaccid paralysis child. Data were collected throughout the country as a routine surveillance program. RESULTS: Of 1299 families analyzed, 907(69.3%) of families with AFP child first went to health institutions to seek medical care, while. 398 (30.7%) of parents took their child first to other traditional sites, including holy water sites (11.8%), traditional healers (9.1%) and prayer places (5.4%). Over half of the parents with AFP child reported practicing home measures before first seeking health service from modern health institutions. Home measures (OR, 0.1202, 95% CI 0.0804-0.1797), decision by relatives (OR, 0.5595, 95% CI 0.3665-0.8540) and More than 10km distance from health facility (OR, 0.5962, 95% CI, 0.4117-0.8634) were significantly associated to first seeking health service from health institutions (p<0.05). CONCLUSION: Program strategies must certainly be developed to expand and capture all traditional sites in the surveillance network, and intensify sensitization and active surveillance visit in these areas.
[Mh] Termos MeSH primário: Assistência à Saúde/métodos
Paralisia/terapia
Aceitação pelo Paciente de Cuidados de Saúde/estatística & dados numéricos
Poliomielite/terapia
[Mh] Termos MeSH secundário: Doença Aguda
Adolescente
Criança
Pré-Escolar
Estudos Transversais
Assistência à Saúde/estatística & dados numéricos
Etiópia
Seres Humanos
Masculino
Medicina Tradicional Africana/utilização
Paralisia/etiologia
Pais
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171030
[Lr] Data última revisão:
171030
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171007
[St] Status:MEDLINE
[do] DOI:10.11604/pamj.supp.2017.27.2.11023



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