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[PMID]:29506498
[Au] Autor:Zhang Y; Chen YG
[Ad] Endereço:Department of Ophthalmology, Peking University Third Hospital, 49 North Huayuan Road, Haidian District, Beijing, 100191, China.
[Ti] Título:High incidence of rainbow glare after femtosecond laser assisted-LASIK using the upgraded FS200 femtosecond laser.
[So] Source:BMC Ophthalmol;18(1):71, 2018 Mar 05.
[Is] ISSN:1471-2415
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: To compare the incidence of rainbow glare (RG) after femtosecond laser assisted-LASIK (FS-LASIK) using the upgraded FS200 femtosecond laser with different flap cut parameter settings. METHODS: A consecutive series of 129 patients (255 eyes) who underwent FS-LASIK for correcting myopia and/or astigmatism using upgraded WaveLight FS200 femtosecond laser with the original settings was included in group A. Another consecutive series of 129 patients (255 eyes) who underwent FS-LASIK using upgraded WaveLight FS200 femtosecond laser with flap cut parameter settings changed (decreased pulse energy, spot and line separation) was included in group B. The incidence and fading time of RG, confocal microscopic image and postoperative clinical results were compared between the two groups. RESULTS: There were no differences between the two groups in age, baseline refraction, excimer laser ablation depth, postoperative uncorrected visual acuity and refraction. The incidence rate of RG in group A (35/255, 13.73%) was significantly higher than that in group B (4/255, 1.57%) (P < 0.05). The median fading time was 3 months in group A and 1 month in group B (P > 0.05).The confocal microscopic images showed wider laser spot spacing in group A than group B. The incidence of RG was significantly correlated with age and grouping (P < 0.05). CONCLUSIONS: The upgraded FS200 femtosecond laser with original flap cut parameter settings could increase the incidence of RG. The narrower grating size and lower pulse energy could ameliorate this side effect.
[Mh] Termos MeSH primário: Astigmatismo/cirurgia
Ofuscação
Ceratomileuse Assistida por Excimer Laser In Situ/métodos
Lasers de Excimer/efeitos adversos
Miopia/cirurgia
Transtornos da Visão/epidemiologia
[Mh] Termos MeSH secundário: Adulto
Seres Humanos
Incidência
Ceratomileuse Assistida por Excimer Laser In Situ/instrumentação
Microscopia Confocal
Refração Ocular/fisiologia
Estudos Retrospectivos
Retalhos Cirúrgicos
Tomografia de Coerência Óptica
Transtornos da Visão/fisiopatologia
Acuidade Visual/fisiologia
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180311
[Lr] Data última revisão:
180311
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180307
[St] Status:MEDLINE
[do] DOI:10.1186/s12886-018-0734-1


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[PMID]:29505511
[Au] Autor:Grzybowski A; Elikowski W; Gaca-Wysocka M
[Ad] Endereço:Department of Ophthalmology, Poznan City Hospital, Poznan.
[Ti] Título:Cardiovascular risk factors in patients with combined central retinal vein occlusion and cilioretinal artery occlusion: Case report.
[So] Source:Medicine (Baltimore);97(1):e9255, 2018 Jan.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:RATIONALE: To analyze cardiovascular risk factors and comorbidity of acute unilateral visual loss due to combined central retinal vein occlusion (CRVO) and cilioretinal artery occlusion (CLRAO). PATIENT CONCERNS: Among patients with retinal vein or artery occlusion hospitalized at the Department of Ophthalmology between January 2011 and August 2017, subjects with combined CRVO/CLRAO were selected. All of them underwent ophthalmologic and cardiologic examination, including fluorescein angiography, optical coherence tomography, 12-lead electrocardiogram, transthoracic and transesophageal echocardiography, carotid Doppler sonography, cerebral magnetic resonance imaging, and a panel of laboratory tests. DIAGNOSES: Four subjects with coexisting CRVO and CLRAO were found among 146 patients with retinal vein or artery occlusion. There were no other types of concomitance of CRVO and retinal artery occlusion. INTERVENTIONS: All patients were treated with low molecular heparin in a full dose for 2 weeks, then with 1 mg/kg once daily for the next 2 weeks, followed by acetylsalicylic acid 75 mg/kg/d. Other medication included long-term statins, angiotensin-converting-enzyme inhibitor in 3 patients and beta-blocker in one patient. OUTCOMES: All patients with CRVO/CLRAO presented multiple cardiovascular risk factors, including hypertension, obesity, hyperlipidemia, chronic nicotine addiction, and a positive family history of coronary artery disease or stroke. In all of them, echocardiography revealed left ventricular hypertrophy and atherosclerotic lesions in the descending aorta; in addition, 3 patients had insignificant atherosclerotic plaques in the carotid artery. Also, in 3 subjects, focal ischemic cerebral changes were diagnosed. LESSONS: Patients with combined CRVO and CLRAO present numerous cardiovascular risk factors and abnormalities on imaging examinations, which should be routinely evaluated and treated.
[Mh] Termos MeSH primário: Oclusão da Artéria Retiniana/complicações
Oclusão da Veia Retiniana/complicações
Transtornos da Visão/etiologia
[Mh] Termos MeSH secundário: Adulto
Idoso de 80 Anos ou mais
Artérias Carótidas/diagnóstico por imagem
Pré-Escolar
Ecocardiografia Transesofagiana
Feminino
Seres Humanos
Imagem por Ressonância Magnética
Masculino
Meia-Idade
Neuroimagem
Oclusão da Artéria Retiniana/diagnóstico por imagem
Oclusão da Veia Retiniana/diagnóstico por imagem
Fatores de Risco
Transtornos da Visão/diagnóstico por imagem
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180306
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000009255


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[PMID]:29499674
[Au] Autor:Casas P; Ascaso FJ; Vicente E; Tejero-Garcés G; Adiego MI; Cristóbal JA
[Ad] Endereço:Department of Ophthalmology, Hospital Clínico Universitario "Lozano Blesa", San Juan Bosco 15, ES-50009, Zaragoza, Spain. paulacasaspascual@hotmail.com.
[Ti] Título:Visual field defects and retinal nerve fiber imaging in patients with obstructive sleep apnea syndrome and in healthy controls.
[So] Source:BMC Ophthalmol;18(1):66, 2018 Mar 02.
[Is] ISSN:1471-2415
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: To assess the retinal sensitivity in obstructive sleep apnea hypopnea syndrome (OSAHS) patients evaluated with standard automated perimetry (SAP). And to correlate the functional SAP results with structural parameters obtained with optical coherence tomography (OCT). METHODS: This prospective, observational, case-control study consisted of 63 eyes of 63 OSAHS patients (mean age 51.7 ± 12.7 years, best corrected visual acuity ≥20/25, refractive error less than three spherical or two cylindrical diopters, and intraocular pressure < 21 mmHg) who were enrolled and compared with 38 eyes of 38 age-matched controls. Peripapillary retinal nerve fiber layer (RNFL) thickness was measured by Stratus OCT and SAP sensitivities and indices were explored with Humphrey Field Analyzer perimeter. Correlations between functional and structural parameters were calculated, as well as the relationship between ophthalmologic and systemic indices in OSAHS patients. RESULTS: OSAHS patients showed a significant reduction of the sensitivity for superior visual field division (p = 0.034, t-student test). When dividing the OSAHS group in accordance with the severity of the disease, nasal peripapillary RNFL thickness was significantly lower in severe OSAHS than that in controls and mild-moderate cases (p = 0.031 and p = 0.016 respectively, Mann-Whitney U test). There were no differences between groups for SAP parameters. We found no correlation between structural and functional variables. The central visual field sensitivity of the SAP revealed a poor Pearson correlation with the apnea-hipopnea index (0.284, p = 0.024). CONCLUSIONS: Retinal sensitivity show minor differences between healthy subjects and OSAHS. Functional deterioration in OSAHS patients is not easy to demonstrate with visual field examination.
[Mh] Termos MeSH primário: Fibras Nervosas/patologia
Doenças do Nervo Óptico/etiologia
Células Ganglionares da Retina/patologia
Apneia Obstrutiva do Sono/complicações
Transtornos da Visão/etiologia
Campos Visuais
[Mh] Termos MeSH secundário: Estudos de Casos e Controles
Feminino
Voluntários Saudáveis
Seres Humanos
Masculino
Meia-Idade
Doenças do Nervo Óptico/diagnóstico
Estudos Prospectivos
Apneia Obstrutiva do Sono/diagnóstico
Tomografia de Coerência Óptica
Transtornos da Visão/diagnóstico
Testes de Campo Visual
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180304
[St] Status:MEDLINE
[do] DOI:10.1186/s12886-018-0728-z


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[PMID]:29441972
[Au] Autor:Sakurada H; Yasuhara K; Kato K; Asano S; Yoshida M; Yamamura M; Tachi T; Teramachi H
[Ti] Título:An investigation of visual hallucinations associated with voriconazole administration to patients with hematological malignancies.
[So] Source:Pharmazie;71(11):660-664, 2016 Nov 02.
[Is] ISSN:0031-7144
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:Voriconazole (VRCZ) is commonly administered to treat fungal infections in patients with hematological malignancies. Some of these patients experience VRCZ-associated visual hallucinations. We conducted a retrospective survey to investigate the characteristic features of this side effect. Patients with hematological malignancies who were treated with VRCZ for a fungal infection after hospitalization at Ichinomiya municipal hospital between 1 October 2005 and 31 December 2015 were included in this study (n = 103). Fifteen of these (14.6%) reported visual hallucinations that started on day 1-7. Seven of these 15 patients developed this symptom rapidly (day 1 or 2). Three patients had transient symptoms (lasting 2-12 days), 6 patients experienced hallucinations throughout the treatment, and the duration was unknown in 6 patients. Eleven patients experienced visual hallucinations when their eyes were closed (73 %) and these disappeared when they opened their eyes. One patient had visual hallucinations with open eyes, while the state of the eyes was unknown in 3 patients. The patients saw a range of images including people, animals, landscapes, and foods; several reported seeing images like those found in movies. In addition, 9 of 15 patients (60%) with visual hallucinations had visual disturbances. This was a higher proportion than that observed in patients who did not develop hallucinations (17 of 88; 19.3 %; P < 0.05). However, we found no significant difference between the blood VCRZ concentrations of patients who developed or did not develop visual hallucinations. This study indicated that most of these patients had visual hallucinations that manifested on eye closure, and they did not progress to serious mental illness. Our findings emphasized the importance of fully explaining the features of this symptom to each patient prior to starting VRCZ administration in order to reduce anxiety. In addition, since VRCZ discontinuation will compromise patient management, therapeutic drug monitoring should be used to increase the likelihood of successful therapy.
[Mh] Termos MeSH primário: Antifúngicos/efeitos adversos
Alucinações/induzido quimicamente
Neoplasias Hematológicas/complicações
Neoplasias Hematológicas/psicologia
Voriconazol/efeitos adversos
[Mh] Termos MeSH secundário: Adulto
Idoso
Idoso de 80 Anos ou mais
Antifúngicos/sangue
Antifúngicos/uso terapêutico
Feminino
Alucinações/epidemiologia
Alucinações/psicologia
Seres Humanos
Incidência
Masculino
Meia-Idade
Micoses/complicações
Micoses/prevenção & controle
Estudos Retrospectivos
Transtornos da Visão/induzido quimicamente
Transtornos da Visão/epidemiologia
Voriconazol/sangue
Voriconazol/uso terapêutico
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antifungal Agents); JFU09I87TR (Voriconazole)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180215
[St] Status:MEDLINE
[do] DOI:10.1691/ph.2016.6725


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[PMID]:29203741
[Au] Autor:Medvedovska NV; Bukhanovska TM; Shevchyk AA
[Ad] Endereço:Shupyk National Medical Academy Of Postgraduate Education, Kyiv, Ukraine.
[Ti] Título:[Studying of life's quality changes among children of the first three year of life with visual analyzer's congenital pathology as instrument of their social adaptation's formation in the future became a research objective].
[So] Source:Wiad Lek;70(5):917-920, 2017.
[Is] ISSN:0043-5147
[Cp] País de publicação:Poland
[La] Idioma:ukr
[Ab] Resumo:INTRODUCTION: The study of the composite qualities of life is an important component of the quality of provided medical aid. The way of our investigation that was chosen by us, the quality of life of the children of first years of life with the congenital pathology of vision arises the significant problem of assessment of its changes, because children of these ages can't take part in an interview and we adapted the standard questionnaire "Children Visual Function Questionnaire" (CVFQ) with its help the components of quality of the children of first years of life assess their parents. THE AIM: Studying of life's quality changes among children of the first three year of life with visual analyzer's congenital pathology as instrument of their social adaptation's formation in the future became a research objective. MATERIALS AND METHODS: Out-patient and polyclinic units of Kyiv's healthcare institutions in which the medical care is provided to children of the first three years of life, particularly with congenital ophthalmic pathology (3 institutions) were scientific base of a research. We have been used the adapted version of the standardized questionnaire of Children's Visual Function Questionnaire (CVFQ) Felius et al were primary material. (2004) - 498 questionnaires, from them 398 of the main group and 100 of control. The purpose of a research required using the complex of research methods, a basis for which is a system approach, namely: medico-statistical and sociological (the respondents were informed about the purpose and research problems and timely gave the oral voluntary agreement in anonymous poll before the filling of questionnaires) methods. RESULTS: The results of a research has established that parents of children from control group have estimated the general condition of children's vision totally in 89,75 ± 1,33 points vs 60,25 ± 1,96 points according to a total score of children's parents from the main group (the difference was 32,87%, at Ñ€<0,001). In general, the total number of points was 64,89 ± 1,01 vs 84,67 ± 0,92, with a difference in 23,4% (Ñ€<0,001) in the main group, according to life's quality total score of early years children's parents. Our research proves existence of children's life quality changes at the presence of visual violations among them that substantiates expediency of strengthening of early identification and treatment measures of visual function's violations at children, within the approved medico-technological documents. CONCLUSION: Interaction in form of cooperation between the family doctor and children's ophthalmologist within the competences on maintaining children with visual analyzer's violation of functions from the first days of life, allows to perform effective long observation of a family, preventing development of medico-social disadaptation both the child, and a family in which it appeared. Research results of life's quality components changes are informative for a future social functioning of the child, his family, the parent's attitude to a child's disease and it's treatments, and performance of disease's treatment.
[Mh] Termos MeSH primário: Adaptação Psicológica
Comportamento Infantil/psicologia
Relações Pais-Filho
Qualidade de Vida
Transtornos da Visão/psicologia
Acuidade Visual
[Mh] Termos MeSH secundário: Estudos de Casos e Controles
Pré-Escolar
Seres Humanos
Lactente
Recém-Nascido
Comportamento Social
Inquéritos e Questionários
Ucrânia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171206
[St] Status:MEDLINE


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[PMID]:29489658
[Au] Autor:Huang KH; Tai MC; Lee LC; Weng TH; Chen YH; Lin LF; Chen JT; Lu DW; Chen CL
[Ad] Endereço:Department of Ophthalmology, Tri-Service General Hospital.
[Ti] Título:Positron emission tomography/computed tomography scan of Vogt-Koyanagi-Harada syndrome with associated autoimmune thyroid disease: A case report and literature review.
[So] Source:Medicine (Baltimore);97(9):e0047, 2018 Mar.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:RATIONALE: Vogt-Koyanagi-Harada (VKH) syndrome is a rare disease and could be associated with autoimmune thyroid disease (AITD). This report was aimed to investigate the utility of F-fludeoxyglucose positron emission tomography/computed tomography (F-FDG PET/CT) for the diagnosis of VKH syndrome with AITD and to perform a literature review on the association between the 2 diseases. PATIENT CONCERNS: A 55-year-old woman without the history of ocular trauma suffered from chronic headache. She was presented with painful blurred vision of both eyes with headache for 2 weeks. Ophthalmic evaluations revealed panuveitis, exudative retinal detachment, and papilloedema in both eyes. The clinical symptoms and presentations are compatible with the diagnosis of VKH syndrome. Other examinations for intraocular infection, malignancy, and lupus choroidopathy were of negative results. The result of contrast-enhanced computed tomography (CT) of the brain was normal. Due to the history of cancer in the patient's families, a F-FDG PET/CT whole-body scan was performed. The result indicated a focal of 2-fluoro-2-deoxy-D-glucose (FDG) uptake at the right upper lobe of the thyroid. Therefore, the patient's thyroid function was examined and the result indicated euthyroidism with detectable thyroid peroxidase/thyroglobulin antibodies. DIAGNOSES: VKH syndrome with associated AITD. INTERVENTIONS: Treatment with intravenous pulse systemic methylprednisolone (1000 mg daily) was prescribed for 3 days and then shifted gradually to tapered oral steroid medication. OUTCOMES: Symptoms of papillitis and serous retinal detachment of VKH syndrome was relieved after steroid treatment LESSONS:: F-fludeoxyglucose positron emission tomography/computed tomography (F-FDG PET/CT) can be used for the effective diagnosis of VKH syndrome with AITD.
[Mh] Termos MeSH primário: Tomografia Computadorizada com Tomografia por Emissão de Pósitrons
Tireoidite Autoimune/complicações
Tireoidite Autoimune/diagnóstico por imagem
Síndrome Uveomeningoencefálica/complicações
Síndrome Uveomeningoencefálica/diagnóstico por imagem
[Mh] Termos MeSH secundário: Feminino
Fluordesoxiglucose F18
Glucocorticoides/uso terapêutico
Cefaleia/etiologia
Seres Humanos
Metilprednisolona/uso terapêutico
Meia-Idade
Tireoidite Autoimune/tratamento farmacológico
Síndrome Uveomeningoencefálica/tratamento farmacológico
Transtornos da Visão/etiologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Glucocorticoids); 0Z5B2CJX4D (Fluorodeoxyglucose F18); X4W7ZR7023 (Methylprednisolone)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180305
[Lr] Data última revisão:
180305
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180301
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000010047


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[PMID]:29424207
[Au] Autor:Mirskaya NB; Sinyakina AD; Kolomenskaya AN
[Ti] Título:[Shaping a healthy lifestyle as necessary condition for prevention of disorders and diseases of visual organ in younger schoolchildren].
[So] Source:Gig Sanit;95(5):466-70, 2016.
[Is] ISSN:0016-9900
[Cp] País de publicação:Russia (Federation)
[La] Idioma:rus
[Ab] Resumo:Purpose. Study of the lifestyle and identification of behavioral risk factors negatively affecting on the state of the visual organ in primary school children. Patients and methods. There was performed a questionnaire survey of parents of 384 younger schoolchildren in Moscow. Questionnaire specially designed by authors included questions relating to lifestyle and behavioral risk factors that affect vision. Results. More than 46% of the younger schoolchildren in the mode of the day have no daily walks in the fresh air, including during daylight hours in 51.6%; time daily needed for this age on air is spent by only 32.8% of schoolchildren. Among younger schoolchildren every day 57.2%, 44.8% and 39.5% spend longer time than needed for homework, TV and computer correspondingly; all the time only 9.4% keepproperfit at their desk, 15.6% at the computer, 20.8% - when watch television; 40.6% do not constantly comply with the requirements for proper illumination while watching TV; 45.8% sometimes read in lyingposition , 9.9% - in transport. Conclusion. Identified in junior schoolchildren of the city of Moscow a high prevalence of behavioral risk factors that negatively affect their visual organ and health in general, requires the elimination of these factors by means of hygienic education and shaping a healthy lifestyle in schoolchildren since 1st grade.
[Mh] Termos MeSH primário: Atitude Frente aos Computadores
Estilo de Vida Saudável/fisiologia
Serviços de Saúde Escolar/organização & administração
Transtornos da Visão
[Mh] Termos MeSH secundário: Criança
Feminino
Seres Humanos
Masculino
Determinação de Necessidades de Cuidados de Saúde
Pais/psicologia
Medição de Risco/estatística & dados numéricos
Fatores de Risco
Federação Russa/epidemiologia
Inquéritos e Questionários
Transtornos da Visão/epidemiologia
Transtornos da Visão/etiologia
Transtornos da Visão/prevenção & controle
Transtornos da Visão/psicologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180301
[Lr] Data última revisão:
180301
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180210
[St] Status:MEDLINE


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[PMID]:29390260
[Au] Autor:Chiang HH; Wieland RS; Rogers TS; Gibson PC; Atweh G; McCormick G
[Ad] Endereço:University of Vermont College of Medicine.
[Ti] Título:Paraproteinemic keratopathy in monoclonal gammopathy of undetermined significance treated with primary keratoprosthesis: Case report, histopathologic findings, and world literature review.
[So] Source:Medicine (Baltimore);96(50):e8649, 2017 Dec.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:RATIONALE: We report a case of paraproteinemic keratopathy associated with monoclonal gammopathy of undetermined significance, treated with keratoprosthesis as a primary penetrating procedure. Histopathological findings and a world literature review are presented. PATIENT CONCERNS: A 74 year old female recently diagnosed with monoclonal gammopathy undetermined significance presented with progressive blurry vision bilaterally. DIAGNOSES: Examination revealed corneal opacities consistent with paraproteinemic keratopathy. INTERVENTIONS: Corneal transplantation with the Boston Type I keratoprosthesis was performed on the right and, a year later, on the left. OUTCOMES: Visual outcomes were good. Histopathological staining of host corneal buttons were consistent with monoclonality, and electron microscopy revealed fibrillar extracellular aggregates within intervening normal stroma. LESSONS: Corneal deposits may be the only manifestation of monoclonal gammopathy of undetermined significance in patients who are otherwise systemically asymptomatic. Ophthalmologists who encounter corneal opacities may order the appropriate diagnostic studies to determine the presence of occult systemic disease. Risk of graft failure after penetrating keratoplasty from recurring opacities is high, so keratoprosthesis as a primary penetrating procedure may afford superior long-term outcomes. Host corneal buttons retrieved from penetrating keratoplasty or corneal biopsy may be sent for histopathological examination to confirm the diagnosis.
[Mh] Termos MeSH primário: Doenças da Córnea/etiologia
Opacidade da Córnea/etiologia
Gamopatia Monoclonal de Significância Indeterminada/complicações
Paraproteinemias/complicações
[Mh] Termos MeSH secundário: Idoso
Doenças da Córnea/cirurgia
Opacidade da Córnea/cirurgia
Transplante de Córnea
Feminino
Seres Humanos
Transtornos da Visão/etiologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180301
[Lr] Data última revisão:
180301
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180203
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000008649


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[PMID]:29465569
[Au] Autor:Kang MJ; Joo CK
[Ad] Endereço:Department of Ophthalmology and Catholic Institute for Visual Science, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
[Ti] Título:Three cases of a torn haptic after scleral fixation using a hydrophobic acrylic intraocular lens: Case reports.
[So] Source:Medicine (Baltimore);97(8):e9853, 2018 Feb.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:RATIONALE: We report 3 cases of a torn haptic after successful scleral fixation with a hydrophobic acrylic intraocular lens. PATIENT CONCERNS: Patients complained of decreased visual acuity about 1 week to 1 month after scleral fixation. DIAGNOSES: In all 3 cases, the direction of the damaged haptic correlated with the direction of the pulling force made by the hung suture material. Observation of a cheese-wiring effect on scanning electron microscopy suggested that the haptic was cut by the suture. INTERVENTIONS: Patients underwent re-scleral fixation with caution. OUCTOMES: There was no complication of broken haptic after re-scleral fixation. LESSONS: To avoid unexpected haptic tears, great caution is needed; surgeons should avoid applying excessive pulling force to the intraocular lens when performing scleral fixation using a hydrophobic acrylic intraocular lens.
[Mh] Termos MeSH primário: Implante de Lente Intraocular/métodos
Lentes Intraoculares
Esclera/cirurgia
[Mh] Termos MeSH secundário: Acrilatos
Idoso
Feminino
Seres Humanos
Masculino
Meia-Idade
Complicações Pós-Operatórias
Reoperação
Técnicas de Sutura
Transtornos da Visão/etiologia
Adulto Jovem
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Acrylates)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180227
[Lr] Data última revisão:
180227
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180222
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000009853


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[PMID]:29465562
[Au] Autor:Wang C; Li J
[Ad] Endereço:Department of Neurology & Acupuncture and Moxibustion Centre, Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University, Beijing.
[Ti] Título:Subacute onset leukodystrophy and visual-spatial disorders revealing phenylketonuria combined with homocysteinmia in adulthood: A case report.
[So] Source:Medicine (Baltimore);97(8):e9801, 2018 Feb.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:RATIONALE: Phenylketonuria (PKU) is a metabolic disorder, which manifests a progressive irreversible neurological impairment during infancy and childhood. Hyperhomocysteinemia also showed that it might be involved in pathophysiology of many neuropsychiatric disorders. The late-onset clinical manifestations of these 2 diseases have not been reported elsewhere. We speculated that the late-onset PKU is caused by 2 kinds of metabolic dysfunction synergistically, especially a short period of irregular diet directly caused clinical symptoms. PATIENT CONCERNS: A 21-year old Asian male patient demonstrated subacute leukodystrophy and visual-spatial disorders of late onset in adulthood. DIAGNOSES: Phenylketonuria combined with homocysteinmia, who presented with heterozygous mutations in gene encoding PAH p.G247R (c.739G>C) and p.Y204C (c.611A>G), along with homozygous mutation of gene encoding MTHFR c.677C>T. INTERVENTIONS: The patient was treated with cobalamine (500 µg/day), vitamin B6 (30 mg/day), folate (5 mg/day) and encouraged to follow a protein-restricted diet. OUTCOMES: Visual disorientation and cognitive function showed improvement. Head MR showed similar resolution with the original lesion. Serum homocysteine and folate analysis were normal with decreased phenylalanine level. LESSONS: This case suggests that neurological involvement of progressive nervous system dysfunction could be caused by more than one kind of inherited metabolic disturbances, and each one can induce or deteriorate the manifestations of another metabolic disorders.
[Mh] Termos MeSH primário: Hiper-Homocisteinemia/diagnóstico
Leucoencefalopatias/etiologia
Fenilcetonúrias/diagnóstico
Transtornos da Visão/etiologia
[Mh] Termos MeSH secundário: Ácido Fólico/uso terapêutico
Seres Humanos
Hiper-Homocisteinemia/tratamento farmacológico
Hiper-Homocisteinemia/genética
Masculino
Mutação
Fenilcetonúrias/tratamento farmacológico
Fenilcetonúrias/genética
Vitamina B 12/uso terapêutico
Vitamina B 6/uso terapêutico
Complexo Vitamínico B/uso terapêutico
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
12001-76-2 (Vitamin B Complex); 8059-24-3 (Vitamin B 6); 935E97BOY8 (Folic Acid); P6YC3EG204 (Vitamin B 12)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180227
[Lr] Data última revisão:
180227
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180222
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000009801



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