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[PMID]:29381747
[Au] Autor:Devyatko D; Pastukhov A
[Ad] Endereço:Laboratory for Cognitive Research, National Research University Higher School of Economics, Moscow, Russia.
[Ti] Título:Extrinsic grouping factors in motion-induced blindness.
[So] Source:PLoS One;13(1):e0192133, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:We investigated how various grouping factors altered subjective disappearances of the individual targets in the motion-induced blindness display. The latter relies on a moving mask to render highly salient static targets temporarily subjectively invisible. Specifically, we employed two extrinsic grouping factors, the connectedness and the common region, and examined whether their presence would make targets more resilient against the suppression. In addition, we investigated whether the presence of an illusory Kanizsa triangle would affect the suppression of the inducing Pac-Man elements. We quantified the perceptual dynamics using the proportion of the disappearance time (this indicates whether targets became more resilient against the suppression), and the proportion of simultaneous disappearance and reappearance events (characterizes the tendency for the targets to disappear or reappear as a group). We report that a single mask that encompassed all targets (a common region grouping) significantly increased the proportion of simultaneous disappearance and reappearance events, but had no effect on the proportion of the disappearance time. In contrast, a line that connected two targets significantly decreased the total invisibility time, but had no impact on the simultaneity of the disappearance and reappearance events. We found no statistically significant effect of the presence of the illusory Kanizsa triangle on either measure. Finally, we found no interaction either between the common region and the connectedness or between the common region and the presence of the illusory Kanizsa triangle. Our results indicate that extrinsic grouping factors might influence the perception differently than the intrinsic ones and highlight the importance of using several measures to characterize the perceptual dynamics, as various grouping factors might affect it differentially.
[Mh] Termos MeSH primário: Cegueira
Percepção de Movimento
[Mh] Termos MeSH secundário: Adolescente
Adulto
Feminino
Seres Humanos
Masculino
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180131
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0192133


  2 / 16714 MEDLINE  
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[PMID]:29320823
[Au] Autor:Shin J; Ahn KS; Suh GH; Kim HJ; Jeong HS; Kim BS; Choi E; Shin SS
[Ad] Endereço:Department of Parasitology, College of Veterinary Medicine, Chonnam National University, Gwangju 61186, Korea.
[Ti] Título:First Blindness Cases of Horses Infected with Setaria Digitata (Nematoda: Filarioidea) in the Republic of Korea.
[So] Source:Korean J Parasitol;55(6):667-671, 2017 Dec.
[Is] ISSN:1738-0006
[Cp] País de publicação:Korea (South)
[La] Idioma:eng
[Ab] Resumo:Ocular setariases of cattle were reported but those of equine hosts have never been reported in the Republic of Korea (Korea). We found motile worms in the aqueous humor of 15 horses (Equus spp.) from 12 localities in southern parts of Korea between January 2004 and November 2017. After the affected animals were properly restrained under sedation and local anesthesia, 10 ml disposable syringe with a 16-gauge needle was inserted into the anterior chamber of the affected eye to successfully remove the parasites. The male worm that was found in 7 of the cases showed a pair of lateral appendages near the posterior terminal end of the body. The papillar arrangement was 3 pairs of precloacal, a pair of adcloacal, and 3 pairs of postcloacal papillae, plus a central papilla just in front of the cloaca. The female worms found in the eyes of 8 horses were characterized by the tapering posterior terminal end of the body with a smooth knob. Worms were all identified as Setaria digitata (von Linstow, 1906) by the morphologic characteristics using light and electron microscopic observations. This is the first blindness cases of 15 horses infected with S. digitata (Nematoda: Filarioidea) in Korea.
[Mh] Termos MeSH primário: Cegueira/etiologia
Cegueira/veterinária
Doenças dos Cavalos/etiologia
Doenças dos Cavalos/parasitologia
Cavalos
Procedimentos Cirúrgicos Oftalmológicos/veterinária
Setaria (Nematoide)/isolamento & purificação
Setaríase/complicações
Setaríase/parasitologia
[Mh] Termos MeSH secundário: Animais
Cegueira/cirurgia
Feminino
Doenças dos Cavalos/cirurgia
Masculino
Microscopia Eletrônica
Procedimentos Cirúrgicos Oftalmológicos/métodos
República da Coreia
Setaria (Nematoide)/anatomia & histologia
Setaria (Nematoide)/ultraestrutura
Setaríase/cirurgia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180112
[St] Status:MEDLINE
[do] DOI:10.3347/kjp.2017.55.6.667


  3 / 16714 MEDLINE  
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[PMID]:27772649
[Au] Autor:Raven ML; Burris CK; Potter HD
[Ad] Endereço:Department of Ophthalmology and Visual Sciences, University of Wisconsin - Madison.
[Ti] Título:Scleritis with Devastating Consequences.
[So] Source:Ophthalmology;123(11):2337, 2016 11.
[Is] ISSN:1549-4713
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Cegueira/etiologia
Esclerite/complicações
[Mh] Termos MeSH secundário: Adulto
Doenças da Córnea/etiologia
Enucleação Ocular
Glaucoma/induzido quimicamente
Glucocorticoides/efeitos adversos
Seres Humanos
Masculino
Recidiva
Esclerite/diagnóstico
Esclerite/tratamento farmacológico
Doenças da Úvea/etiologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Glucocorticoids)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161025
[St] Status:MEDLINE


  4 / 16714 MEDLINE  
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[PMID]:29403335
[Au] Autor:Wong SH; Turbin RE; Frohman LP
[Ad] Endereço:Institute of Ophthalmology & Visual Science, Rutgers New Jersey Medical School, Newark.
[Ti] Título:Takayasu arteritis-related photic and postprandial amaurosis.
[So] Source:Digit J Ophthalmol;23(4):13-14, 2017.
[Is] ISSN:1542-8958
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:We report the case of a 66-year-old man with Takayasu arteritis who developed photic and postprandial amaurosis occurring at a corticosteroid dose <40 mg per day, despite concurrent methotrexate. The amaurosis resolved with correction of anemia by packed red blood cell transfusion. Marginal retinal perfusion in Takayasu arteritis may precipitate symptomatic hypoxia as a result of eating a meal or exposing the eye to bright lights. Correction of anemia improves oxygen delivery to the hypoxic retina and relieves recurrent amaurosis.
[Mh] Termos MeSH primário: Cegueira/etiologia
Período Pós-Prandial
Arterite de Takayasu/complicações
[Mh] Termos MeSH secundário: Idoso
Artéria Axilar/diagnóstico por imagem
Cegueira/diagnóstico
Cegueira/fisiopatologia
Diagnóstico Diferencial
Angiofluoresceinografia/métodos
Fundo de Olho
Seres Humanos
Angiografia por Ressonância Magnética
Masculino
Vasos Retinianos/diagnóstico por imagem
Artéria Subclávia/diagnóstico por imagem
Arterite de Takayasu/diagnóstico
Acuidade Visual
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180306
[Lr] Data última revisão:
180306
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180207
[St] Status:MEDLINE
[do] DOI:10.5693/djo.02.2017.09.002


  5 / 16714 MEDLINE  
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Registro de Ensaios Clínicos
Registro de Ensaios Clínicos
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[PMID]:29320647
[Au] Autor:Bassler D; Shinwell ES; Hallman M; Jarreau PH; Plavka R; Carnielli V; Meisner C; Engel C; Koch A; Kreutzer K; van den Anker JN; Schwab M; Halliday HL; Poets CF; Neonatal European Study of Inhaled Steroids Trial Group
[Ad] Endereço:From the Department of Neonatology, University Hospital Zurich, University of Zurich, Zurich (D.B.), and the Division of Pediatric Pharmacology and Pharmacometrics, University of Basel Children's Hospital, Basel (J.N.A.) - both in Switzerland; Ziv Medical Center, Faculty of Medicine in the Galilee,
[Ti] Título:Long-Term Effects of Inhaled Budesonide for Bronchopulmonary Dysplasia.
[So] Source:N Engl J Med;378(2):148-157, 2018 01 11.
[Is] ISSN:1533-4406
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The long-term effects on neurodevelopment of the use of inhaled glucocorticoids in extremely preterm infants for the prevention or treatment of bronchopulmonary dysplasia are uncertain. METHODS: We randomly assigned 863 infants (gestational age, 23 weeks 0 days to 27 weeks 6 days) to receive early (within 24 hours after birth) inhaled budesonide or placebo. The prespecified secondary long-term outcome was neurodevelopmental disability among survivors, defined as a composite of cerebral palsy, cognitive delay (a Mental Development Index score of <85 [1 SD below the mean of 100] on the Bayley Scales of Infant Development, Second Edition, with higher scores on the scale indicating better performance), deafness, or blindness at a corrected age of 18 to 22 months. RESULTS: Adequate data on the prespecified composite long-term outcome were available for 629 infants. Of these infants, 148 (48.1%) of 308 infants assigned to budesonide had neurodevelopmental disability, as compared with 165 (51.4%) of 321 infants assigned to placebo (relative risk, adjusted for gestational age, 0.93; 95% confidence interval [CI], 0.80 to 1.09; P=0.40). There was no significant difference in any of the individual components of the prespecified outcome. There were more deaths in the budesonide group than in the placebo group (82 [19.9%] of 413 infants vs. 58 [14.5%] of 400 infants for whom vital status was available; relative risk, 1.37; 95% CI, 1.01 to 1.86; P=0.04). CONCLUSIONS: Among surviving extremely preterm infants, the rate of neurodevelopmental disability at 2 years did not differ significantly between infants who received early inhaled budesonide for the prevention of bronchopulmonary dysplasia and those who received placebo, but the mortality rate was higher among those who received budesonide. (Funded by the European Union and Chiesi Farmaceutici; ClinicalTrials.gov number, NCT01035190 .).
[Mh] Termos MeSH primário: Displasia Broncopulmonar/prevenção & controle
Budesonida/administração & dosagem
Deficiências do Desenvolvimento/epidemiologia
Glucocorticoides/administração & dosagem
Lactente Extremamente Prematuro
[Mh] Termos MeSH secundário: Administração por Inalação
Cegueira/epidemiologia
Paralisia Cerebral/epidemiologia
Transtornos Cognitivos/epidemiologia
Feminino
Seguimentos
Idade Gestacional
Perda Auditiva/epidemiologia
Seres Humanos
Recém-Nascido
Doenças do Prematuro/mortalidade
Masculino
[Pt] Tipo de publicação:JOURNAL ARTICLE; MULTICENTER STUDY; RANDOMIZED CONTROLLED TRIAL; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Glucocorticoids); 51333-22-3 (Budesonide)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180228
[Lr] Data última revisão:
180228
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180111
[Cl] Clinical Trial:ClinicalTrial
[St] Status:MEDLINE
[do] DOI:10.1056/NEJMoa1708831


  6 / 16714 MEDLINE  
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[PMID]:29273018
[Au] Autor:de Almeida Ferreira G; Schaal LF; Ferro MD; Rodrigues ACL; Khandekar R; Schellini SA
[Ad] Endereço:Universidade Estadual Paulista Julio de Mesquita Filho Faculdade de Medicina Campus de Botucatu Botucatu, Sao Paulo, Brazil.
[Ti] Título:Outcomes of and barriers to cataract surgery in Sao Paulo State, Brazil.
[So] Source:BMC Ophthalmol;17(1):259, 2017 Dec 22.
[Is] ISSN:1471-2415
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Cataract is the leading cause of blindness in developing countries and identification of the barriers to accessing treatment is essential for developing appropriate public healthcare interventions. To evaluate the barriers to cataract surgery after diagnosis and assess the postoperative outcomes in Sao Paolo State, Brazil. METHODS: This prospective study evaluated cataract patients from 13 counties in São Paulo State in 2014. Cataract was diagnosed in the community by a mobile ophthalmic unit and patients were referred to a hospital for management. Gender, age, distance to the hospital and local municipal health structure were evaluated as possible barriers. Data were analyzed for postoperative outcomes and the impact on blindness and visual impairment. RESULTS: Six hundred patients were diagnosed with cataract with a mean age of 68.8±10.3 years and 374 (62.3%) were females. Two hundred and fifty-four (42.3%) patients presented to the referral hospital. One hundred forty-four (56.7%) underwent surgery, 56 (22.0%) decided not to undergo surgery, 40 (15.7%) required only YAG-Laser and 14 (5.5%) required a spectacle prescription only. Visual acuity increased statistically significantly from 1.07±0.73 logMAR at presentation to 0.25±0.41 logMAR at the final visit after intraocular lens implantation (p=0.000). There was a statistically significantly decrease from 17 (11.8%) blind patients and 55 (38.2%) visually impaired patients at presentation to 2 (1.4%) and 5 (3.5%) patients respectively after treatment (p=0.000). CONCLUSION: Less than half of the individuals with cataract presented to the hospital for surgery. Among the patients who underwent treatment, there was an overall decrease in the number of blind individuals and visually impaired individuals. The barriers to cataract surgery were older age, greater distance to the hospital, municipalities with fewer inhabitants and less ophthalmic services.
[Mh] Termos MeSH primário: Cegueira/etiologia
Extração de Catarata
Catarata/epidemiologia
Acuidade Visual
Pessoas com Deficiência Visual/reabilitação
[Mh] Termos MeSH secundário: Idoso
Cegueira/epidemiologia
Brasil/epidemiologia
Catarata/complicações
Estudos Transversais
Países em Desenvolvimento
Feminino
Seguimentos
Seres Humanos
Incidência
Masculino
Meia-Idade
Estudos Prospectivos
[Pt] Tipo de publicação:JOURNAL ARTICLE; MULTICENTER STUDY
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180228
[Lr] Data última revisão:
180228
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171224
[St] Status:MEDLINE
[do] DOI:10.1186/s12886-017-0637-6


  7 / 16714 MEDLINE  
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[PMID]:29420144
[Au] Autor:Gilbert AL; Chwalisz B; Mallery R
[Ad] Endereço:a Department of Neuro-Ophthalmology , Massachusetts Eye & Ear, Harvard Medical School , Boston , MA , USA.
[Ti] Título:Complications of Optic Nerve Sheath Fenestration as a Treatment for Idiopathic Intracranial Hypertension.
[So] Source:Semin Ophthalmol;33(1):36-41, 2018.
[Is] ISSN:1744-5205
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:There are a number of surgical options for treatment of idiopathic intracranial hypertension (IIH) when it is refractory to medical treatment and weight loss. Optic nerve sheath fenestration (ONSF) is one of these options. Use of this procedure varies among centers due to experience with the procedure and concern for associated complications that can result in severe loss of vision. This review summarizes the literature concerning post-surgical complications of ONSF for IIH.
[Mh] Termos MeSH primário: Cegueira
Descompressão Cirúrgica/efeitos adversos
Procedimentos Neurocirúrgicos/efeitos adversos
Traumatismos do Nervo Óptico/etiologia
Nervo Óptico/cirurgia
Papiledema/cirurgia
Pseudotumor Cerebral/complicações
[Mh] Termos MeSH secundário: Cegueira/epidemiologia
Cegueira/etiologia
Cegueira/fisiopatologia
Seres Humanos
Nervo Óptico/patologia
Traumatismos do Nervo Óptico/diagnóstico
Traumatismos do Nervo Óptico/fisiopatologia
Papiledema/diagnóstico
Papiledema/etiologia
Complicações Pós-Operatórias
Pseudotumor Cerebral/fisiopatologia
Pseudotumor Cerebral/cirurgia
Acuidade Visual
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180219
[Lr] Data última revisão:
180219
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180209
[St] Status:MEDLINE
[do] DOI:10.1080/08820538.2017.1353810


  8 / 16714 MEDLINE  
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[PMID]:29439666
[Au] Autor:Thapa R; Bajimaya S; Paudyal G; Khanal S; Tan S; Thapa SS; van Rens GHMB
[Ad] Endereço:Vitreo-retina Service, Tilganga Institute of Ophthalmology, P O Box 561, Kathmandu, Nepal. rabathapa@live.com.
[Ti] Título:Prevalence and causes of low vision and blindness in an elderly population in Nepal: the Bhaktapur retina study.
[So] Source:BMC Ophthalmol;18(1):42, 2018 Feb 13.
[Is] ISSN:1471-2415
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: This study aims to explore the prevalence and causes of low vision and blindness focused on retinal disease in a population above 60 years in Nepal. METHODS: Two thousand one hundred subjects were enrolled in a population-based cross-sectional study. History, presenting and best corrected visual acuity after subjective refraction, anterior and posterior segment examinations was obtained in detail. RESULTS: Among the total subjects, 1860 (88.57%) had complete information. Age varies from 60 to 95 (mean age: 69.64 ± 7.31) years. Low vision and blindness in both eyes at presentation was found in 984 (52.90%, 95% confidence interval (CI): 50.60-55.19) and 36 (1.94%, 95% CI: 1.35-2.66) subjects respectively. After best correction, bilateral low vision and blindness was found in 426 (22.92%, 95% CI: 21.01-24.88), and 30 (1.61%, 95% CI: 0.10-2.30) subjects respectively. As compared to 60-69 years old, risk of visual impairment was four times higher (95% CI:3.26-5.58) in the 70-79 year olds and 14 times higher (95% CI: 9.72-19.73) in the age group 80 years and above. Major causes of bilateral low vision were cataract (68.07%), followed by retinal disorders (28.64%), and for blindness; retinal disorders (46.66%), followed by cataract (43.33%). Illiteracy was significantly associated with visual impairment. CONCLUSION: Among the elderly population, prevalence of visual impairment was high. Refractive error, cataract and retinal disorders were the major cause of low vision. Screening the population at the age 60 years and above, focused on cataract and posterior segment diseases, providing glasses and timely referral can help reduce visual impairment.
[Mh] Termos MeSH primário: Cegueira/epidemiologia
Baixa Visão/epidemiologia
Pessoas com Deficiência Visual/estatística & dados numéricos
[Mh] Termos MeSH secundário: Distribuição por Idade
Idoso
Idoso de 80 Anos ou mais
Catarata/epidemiologia
Estudos Transversais
Feminino
Seres Humanos
Masculino
Meia-Idade
Nepal/epidemiologia
Prevalência
Refração Ocular/fisiologia
Erros de Refração/epidemiologia
Doenças Retinianas/epidemiologia
Fatores de Risco
Distribuição por Sexo
Inquéritos e Questionários
Acuidade Visual/fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180218
[Lr] Data última revisão:
180218
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180215
[St] Status:MEDLINE
[do] DOI:10.1186/s12886-018-0710-9


  9 / 16714 MEDLINE  
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[PMID]:29433477
[Au] Autor:Li Y; Huang W; Qiqige A; Zhang H; Jin L; Ti P; Yip J; Xiao B
[Ad] Endereço:The Affiliated Eye Hospital of Nanchang University, Nanchang City, China.
[Ti] Título:Prevalence and causes of blindness, visual impairment among different ethnical minority groups in Xinjiang Uygur autonomous region, China.
[So] Source:BMC Ophthalmol;18(1):41, 2018 Feb 13.
[Is] ISSN:1471-2415
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The aim of this cross-sectional study is to ascertain the prevalence and causes of blindness, visual impairment, uptake of cataract surgery among different ethnic groups in Xinjiang Uygur Autonomous Region, China. METHODS: Four thousand one hundred fifty people at 50 years and above from different minority ethnic groups were randomly selected for an eye examination. The four trained eye teams collected data using tumbling E visual chart, torch, portable slit lamp and direct ophthalmoscope in 2015. The World Health Organization's definition of blindness and visual impairment (VI) was used to classify patients in each ethnic group. Data were analyzed by different minority groups and were compared with Han Chinese. RESULTS: 3977 (95.8%) out of 4150 people were examined. The prevalence of blindness from the study population was 1.7% (95% confidence interval: 1.3-2.2%).There was no significant difference in prevalence of blindness between Han Chinese and people of Khazak and other minority ethnic groups, nor, between male and female. Cataract was the leading course (65.5%) of blindness and uncorrected refractive error was the most common cause of VI (36.3%) followed by myopic retinopathy. The most common barrier to cataract surgery was lack of awareness of service availability. CONCLUSIONS: This study documented a low blindness prevalence among people aged 50 years and over comparing to prevalence identified through studies of other regions in China. It still indicates blindness and un-operated cataract as the significant public health issue, with no evidence of eye health inequalities, but some inequities in accessing to cataract surgery amongst ethnic minority groups in Xinjiang.
[Mh] Termos MeSH primário: Grupo com Ancestrais do Continente Asiático/etnologia
Cegueira/etnologia
Grupos Minoritários/estatística & dados numéricos
Baixa Visão/etnologia
Pessoas com Deficiência Visual/estatística & dados numéricos
[Mh] Termos MeSH secundário: Distribuição por Idade
Idoso
Idoso de 80 Anos ou mais
Catarata/etnologia
China/epidemiologia
Estudos Transversais
Grupos Étnicos
Feminino
Acesso aos Serviços de Saúde/estatística & dados numéricos
Seres Humanos
Masculino
Meia-Idade
Exame Físico
Prevalência
Erros de Refração/etnologia
Doenças Retinianas/etnologia
Distribuição por Sexo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180218
[Lr] Data última revisão:
180218
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180214
[St] Status:MEDLINE
[do] DOI:10.1186/s12886-018-0705-6


  10 / 16714 MEDLINE  
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[PMID]:29323644
[Ti] Título:Vision quest: gene therapy for inherited vision loss.
[So] Source:Lancet;391(10115):2, 2018 01 06.
[Is] ISSN:1474-547X
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Transtornos da Visão
Visão Ocular
[Mh] Termos MeSH secundário: Cegueira
Terapia Genética
Seres Humanos
[Pt] Tipo de publicação:EDITORIAL; COMMENT
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180208
[Lr] Data última revisão:
180208
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180112
[St] Status:MEDLINE



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