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[PMID]:28452700
[Au] Autor:Ghadersohi S; Ference EH; Detwiller K; Kern RC
[Ad] Endereço:Department of Otolaryngology-Head and Neck Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
[Ti] Título:Presentation, workup, and management of penetrating transorbital and transnasal injuries: A case report and systematic review.
[So] Source:Am J Rhinol Allergy;31(2):29-34, 2017 Mar 01.
[Is] ISSN:1945-8932
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: A foreign body (FB) penetrating intracranially after passing transorbitally or transnasally is a rare occurrence. However, otolaryngologists are increasingly being asked to participate in the care of these patients for both endoscopic removal of the object and repair of any skull base defects. OBJECTIVE: To assess the presentation, workup, and management of transnasal or transorbital penetrating FB injury. METHODS: Systematic review of the presentation, workup, and management of transnasal or transorbital penetrating FB injury; plus, a case report of a 53-year-old woman with a transorbital penetrating rose bush branch. We searched medical literature data bases, which resulted in 215 total titles, which were then narrowed based on inclusion and exclusion criteria. RESULTS: Thirty-five cases of transorbital or transnasal low-velocity trauma that involved the paranasal sinuses were reviewed from 33 articles. The average age was 30 years, 40% of the objects were made of wood. Fifty-seven percent of the cases were transorbital, whereas 43% were transnasal. Forty-six percent of the surgical interventions were completed endoscopically or with endoscopic assistance. Complications of injury were common, with 66% of patients experiencing cerebrospinal fluid leaks; 23%, permanent blindness; 17%, meningitis; 14%, ophthalmoplegia; 9%, decreased visual acuity; and 3%, brain abscess. Our patient presented with a traumatic cerebrospinal fluid leak, and recovered well after transorbital and endoscopic removal of the branch, skull base repair, and a prolonged course of antibiotics and antifungal medications. CONCLUSIONS: Transnasal and transorbital penetrating FB injuries are a relatively uncommon occurrence but when they do occur require rapid workup and interdisciplinary management to prevent acute and delayed complications.
[Mh] Termos MeSH primário: Vazamento de Líquido Cefalorraquidiano/epidemiologia
Traumatismos Craniocerebrais/epidemiologia
Endoscopia
Traumatismos Oculares/epidemiologia
Traumatismos Cranianos Penetrantes/epidemiologia
Órbita/cirurgia
Seios Paranasais/cirurgia
Complicações Pós-Operatórias/epidemiologia
[Mh] Termos MeSH secundário: Vazamento de Líquido Cefalorraquidiano/etiologia
Traumatismos Craniocerebrais/cirurgia
Traumatismos Oculares/cirurgia
Feminino
Corpos Estranhos
Traumatismos Cranianos Penetrantes/cirurgia
Seres Humanos
Meia-Idade
Base do Crânio/cirurgia
Estados Unidos/epidemiologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170429
[St] Status:MEDLINE
[do] DOI:10.2500/ajra.2017.31.4421


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[PMID]:28628600
[Au] Autor:Madathil SK; Deng-Bryant Y; Wilfred BS; Leung LY; Gilsdorf JS; Shear DA
[Ad] Endereço:Brain Trauma Neuroprotection and Neurorestoration Branch (S.K.M., Y.D., B.S.W., L.Y.L., J.S.G., D.A.S.), Center for Military Psychiatry and Neuroscience, Walter Reed Army Institute of Research (WRAIR), Silver Spring, Maryland.
[Ti] Título:Alterations in brain-derived neurotrophic factor and insulin-like growth factor-1 protein levels after penetrating ballistic-like brain injury in rats.
[So] Source:J Trauma Acute Care Surg;83(1 Suppl 1):S16-S24, 2017 Jul.
[Is] ISSN:2163-0763
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Brain-derived neurotrophic factor (BDNF) and insulin-like growth factor-1 (IGF-1) are essential for neuroplasticity and neuronal survival. Despite the importance of these endogenous factors in mediating posttraumatic recovery, little is known about their response after penetrating type traumatic brain injury. The objective of this study was to quantify the expression levels BDNF and IGF-1, two well-known neuroplasticity mediators, after penetrating ballistic-like brain injury (PBBI). METHODS: Rats were randomly assigned to receive unilateral sham or PBBI injuries. Using enzyme-linked immunosorbent assay and immunohistochemistry, we performed a comprehensive evaluation of BDNF and IGF-1 expression at acute (1 hour, 6 hours, 1 day) and subacute (2, 3, 7, and 14 days) timepoints after injury. RESULTS: BDNF and IGF-1 expression was transiently upregulated in both cortex and hippocampus after PBBI. Although BDNF levels increased at acute timepoints, IGF-1 expression peaked at 3 days in cortical homogenates. Although there was loss of staining in cells bordering the cavity, increased BDNF and IGF-1 immunoreactivity was observed in scattered neurons away from the contusion site. Glial upregulation of both growth factors was observed at early timepoints in the hippocampus. CONCLUSION: Our findings demonstrate that PBBI results in a brief upregulation of BDNF and IGF-1 during early posttraumatic period, providing critical information for interventions aiming to enhance neuronal survival and brain plasticity.
[Mh] Termos MeSH primário: Fator Neurotrófico Derivado do Encéfalo/metabolismo
Traumatismos Cranianos Penetrantes/metabolismo
Fator de Crescimento Insulin-Like I/metabolismo
[Mh] Termos MeSH secundário: Animais
Ensaio de Imunoadsorção Enzimática
Imuno-Histoquímica
Masculino
Medicina Militar
Distribuição Aleatória
Ratos
Ratos Sprague-Dawley
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Brain-Derived Neurotrophic Factor); 67763-96-6 (Insulin-Like Growth Factor I)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170830
[Lr] Data última revisão:
170830
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170620
[St] Status:MEDLINE
[do] DOI:10.1097/TA.0000000000001471


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[PMID]:28435118
[Au] Autor:Samuthrat T; Ye K; Tong Y
[Ad] Endereço:Department of Neurosurgery, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
[Ti] Título:Transoral Intracranial Injury via Middle Skull Base by a Blunt Chopstick in a Child.
[So] Source:World Neurosurg;103:952.e11-952.e17, 2017 Jul.
[Is] ISSN:1878-8769
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Transoral penetrating injury from a blunt-tipped chopstick is unusual and should be promptly dealt with because it is associated with high morbidity and mortality. CASE DESCRIPTION: We report a case of a 2-year-old girl who sustained a transoral penetrating brain injury after falling onto a bamboo chopstick, which penetrated through the hard palate and eventually led to middle skull base fracture as well as temporal lobe laceration and contusion. The chopstick was successfully extracted via a transoral approach followed by administration of empirical antibiotics and anticonvulsants. The postoperative course was uneventful, and a 2-year follow-up evaluation revealed a favorable outcome. CONCLUSIONS: Preoperative and postoperative imaging and extensive monitoring of the patient's condition are mandatory for evaluation of possible development of complications. An optimal result can be obtained by a tailored management and treatment approach for each specific patient.
[Mh] Termos MeSH primário: Contusão Encefálica/diagnóstico por imagem
Lesões Encefálicas Traumáticas/diagnóstico por imagem
Lesões Encefálicas/diagnóstico por imagem
Encéfalo/diagnóstico por imagem
Corpos Estranhos/diagnóstico por imagem
Traumatismos Cranianos Penetrantes/diagnóstico por imagem
Base do Crânio/diagnóstico por imagem
Fraturas Cranianas/diagnóstico por imagem
Lobo Temporal/lesões
[Mh] Termos MeSH secundário: Pré-Escolar
Feminino
Corpos Estranhos/cirurgia
Seres Humanos
Base do Crânio/lesões
Tomografia Computadorizada por Raios X
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170925
[Lr] Data última revisão:
170925
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170425
[St] Status:MEDLINE


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[PMID]:28398912
[Au] Autor:Valoriani S; Eliopoulos C; Borrini M
[Ad] Endereço:From the School of Natural Sciences and Psychology, Liverpool John Moores University, Liverpool, United Kingdom.
[Ti] Título:Sharp Force Trauma Death in a Young Individual From Medieval Gloucester.
[So] Source:Am J Forensic Med Pathol;38(2):111-114, 2017 Jun.
[Is] ISSN:1533-404X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The authors of the present work evaluate the trauma observed on the skeletal remains of an individual from medieval Gloucester and reconstruct the events that led to his death. The almost complete skeleton was recovered from the cemetery of St Owen and dates to the late medieval period. Several methods were used to determine the sex and age of the individual. The anthropological examination showed that the remains belonged to a young male, between the ages of 17 and 19 years. The young man also had antemortem pathologies that were related to his diet and lifestyle, as he appears to have had iron-deficiency anemia and Schmorl nodes. The trauma observed on the remains consisted of 3 cut marks located on the cranium, left radius, and right scapula. The cuts seem to have been inflicted by a heavy weapon, such as a sword. The trauma pattern observed is consistent with defensive action, and the fact that this skeleton was the only one in the collection that has evidence of trauma suggests that this was a case of interpersonal violence.
[Mh] Termos MeSH primário: Ferimentos Perfurantes/patologia
[Mh] Termos MeSH secundário: Adolescente
Determinação da Idade pelo Esqueleto
Determinação da Idade pelos Dentes
Inglaterra
Traumatismos Cranianos Penetrantes/patologia
História Medieval
Seres Humanos
Masculino
Rádio (Anatomia)/lesões
Rádio (Anatomia)/patologia
Escápula/lesões
Escápula/patologia
Espondilólise/patologia
Adulto Jovem
[Pt] Tipo de publicação:CASE REPORTS; HISTORICAL ARTICLE; JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171011
[Lr] Data última revisão:
171011
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170412
[St] Status:MEDLINE
[do] DOI:10.1097/PAF.0000000000000312


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[PMID]:28271364
[Au] Autor:Mahoney PF; Carr DJ; Delaney RJ; Hunt N; Harrison S; Breeze J; Gibb I
[Ad] Endereço:Royal Centre for Defence Medicine, ICT Centre, Research Park, Birmingham, B15 2SQ, UK. p.f.mahoney@cranfield.ac.uk.
[Ti] Título:Does preliminary optimisation of an anatomically correct skull-brain model using simple simulants produce clinically realistic ballistic injury fracture patterns?
[So] Source:Int J Legal Med;131(4):1043-1053, 2017 Jul.
[Is] ISSN:1437-1596
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:Ballistic head injury remains a significant threat to military personnel. Studying such injuries requires a model that can be used with a military helmet. This paper describes further work on a skull-brain model using skulls made from three different polyurethane plastics and a series of skull 'fills' to simulate brain (3, 5, 7 and 10% gelatine by mass and PermaGel™). The models were subjected to ballistic impact from 7.62 × 39 mm mild steel core bullets. The first part of the work compares the different polyurethanes (mean bullet muzzle velocity of 708 m/s), and the second part compares the different fills (mean bullet muzzle velocity of 680 m/s). The impact events were filmed using high speed cameras. The resulting fracture patterns in the skulls were reviewed and scored by five clinicians experienced in assessing penetrating head injury. In over half of the models, one or more assessors felt aspects of the fracture pattern were close to real injury. Limitations of the model include the skull being manufactured in two parts and the lack of a realistic skin layer. Further work is ongoing to address these.
[Mh] Termos MeSH primário: Balística Forense/instrumentação
Traumatismos Cranianos Penetrantes/patologia
Modelos Biológicos
Fraturas Cranianas/patologia
Ferimentos por Arma de Fogo/patologia
[Mh] Termos MeSH secundário: Gelatina
Géis
Seres Humanos
Teste de Materiais
Poliuretanos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Gels); 0 (Polyurethanes); 9000-70-8 (Gelatin)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171031
[Lr] Data última revisão:
171031
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170309
[St] Status:MEDLINE
[do] DOI:10.1007/s00414-017-1557-y


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[PMID]:28104523
[Au] Autor:Alkufri F; Dabbous B; Shtaya A
[Ad] Endereço:Fadi Alkufri, Islamic Hospital, Amman, Jordan.
[Ti] Título:Intracranial Stray Bullet: Undiagnosed for 4 Decades.
[So] Source:World Neurosurg;100:707.e9, 2017 Apr.
[Is] ISSN:1878-8769
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Encéfalo/diagnóstico por imagem
Traumatismos Cranianos Penetrantes/diagnóstico por imagem
Ferimentos por Arma de Fogo/diagnóstico por imagem
[Mh] Termos MeSH secundário: Tratamento Conservador
Diagnóstico Tardio
Traumatismos Cranianos Penetrantes/terapia
Seres Humanos
Masculino
Meia-Idade
Tomografia Computadorizada por Raios X
Ferimentos por Arma de Fogo/terapia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170918
[Lr] Data última revisão:
170918
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170121
[St] Status:MEDLINE


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[PMID]:28091809
[Au] Autor:Vakil MT; Singh AK
[Ad] Endereço:Massachusetts General Hospital, 55 Fruit Street, Blake SB0029A, Boston, MA, 02114, USA.
[Ti] Título:A review of penetrating brain trauma: epidemiology, pathophysiology, imaging assessment, complications, and treatment.
[So] Source:Emerg Radiol;24(3):301-309, 2017 Jun.
[Is] ISSN:1438-1435
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Gunshot injuries are the most common cause of penetrating brain injury (PBI) and carry a high morbidity and mortality. The incidence of PBI has increased over the last decade with an estimated 35,000 civilian deaths annually. Patients that survive to reach the hospital require rapid triage and imaging evaluation. CT findings in conjunction with the Glasgow Coma Scale are typically used to determine which patients are surgical candidates. Radiologists should be familiar with the various injury patterns and imaging findings which are poor prognostic indicators, notably brainstem, bilateral hemispheric, multilobar, or transventricular injuries. Post-traumatic complications, including intracranial infections, cerebrospinal fluid leaks, traumatic intracranial aneurysms, intraventricular hemorrhage, dural venous sinus thrombus, and bullet fragment migration, also have specific imaging features and serious treatment implications. In this article, we review the initial imaging evaluation of penetrating brain injury using computed tomography with and without angiography. We also describe the imaging features of various post-traumatic complications and their treatment implications. Finally, we discuss the clinical and imaging parameters that serve as important prognostic indicators and the surgical management.
[Mh] Termos MeSH primário: Traumatismos Cranianos Penetrantes/diagnóstico por imagem
Tomografia Computadorizada por Raios X/métodos
Ferimentos por Arma de Fogo/diagnóstico por imagem
[Mh] Termos MeSH secundário: Escala de Coma de Glasgow
Traumatismos Cranianos Penetrantes/complicações
Traumatismos Cranianos Penetrantes/epidemiologia
Traumatismos Cranianos Penetrantes/fisiopatologia
Seres Humanos
Incidência
Prognóstico
Ferimentos por Arma de Fogo/complicações
Ferimentos por Arma de Fogo/epidemiologia
Ferimentos por Arma de Fogo/fisiopatologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171103
[Lr] Data última revisão:
171103
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170117
[St] Status:MEDLINE
[do] DOI:10.1007/s10140-016-1477-z


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[PMID]:28068964
[Au] Autor:Shi J; Mao Y; Cao J; Dong B
[Ad] Endereço:Department of Neurosurgery, The Third Affiliated Hospital of Soochow University, Changzhou City, 213003, China.
[Ti] Título:Management of screwdriver-induced penetrating brain injury: a case report.
[So] Source:BMC Surg;17(1):3, 2017 Jan 10.
[Is] ISSN:1471-2482
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Penetrating brain injury (PBI) can be caused by several objects ranging from knives to chopsticks. However, an assault with long and electric screwdriver is a peculiar accident and is relatively rare. Because of its rarity, the treatments of such injury are complex and nonstandardized. CASE PRESENTATION: We presented a case of a 54-year-old female who was stabbed with a screwdriver in her head and accompanied by loss of consciousness for 1 h. Computer tomography (CT) demonstrated that the screwdriver passed through the right zygomatic bone to posterior cranial fossa. Early foreign body removal and hematoma evacuation were performed and the patient had a good postoperative recovery. CONCLUSIONS: In this study, we discussed the clinical presentation and successful management of such a unique injury caused by a screwdriver. Our goal is to demonstrate certain general management principles which can improve patient outcomes.
[Mh] Termos MeSH primário: Hemorragia Encefálica Traumática/cirurgia
Traumatismos Cranianos Penetrantes/cirurgia
Hemorragia Subaracnoídea Traumática/cirurgia
[Mh] Termos MeSH secundário: Hemorragia Encefálica Traumática/diagnóstico por imagem
Fossa Craniana Posterior/lesões
Feminino
Traumatismos Cranianos Penetrantes/diagnóstico por imagem
Seres Humanos
Meia-Idade
Hemorragia Subaracnoídea Traumática/diagnóstico por imagem
Tomografia Computadorizada por Raios X
Zigoma/lesões
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170111
[St] Status:MEDLINE
[do] DOI:10.1186/s12893-016-0195-5


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[PMID]:27941553
[Au] Autor:Oudrhiri MY; Eabdenbi Tsen A; Fouadi FE; Louraoui SM; Arkha Y; El Ouahabi A
[Ad] Endereço:*Department of Neurosurgery, ONO Hospital, Ibn Sina University Hospital Center †Department of Maxillofacial Surgery, ONO Hospital, Ibn Sina University Hospital Center ‡Department of Plastic Surgery, Mohammed Vth University, Rabat, Morocco..
[Ti] Título:The Transcranial Stab Wound and the Life-Saving Zygomatic Arch Clinical Report.
[So] Source:J Craniofac Surg;28(1):218-219, 2017 Jan.
[Is] ISSN:1536-3732
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:A 58-year-old man presented to the neurosurgical emergencies for a transzygomatic transcranial stab wound with a retained broken knife. The patient was neurologically intact. After radiographic evaluation the knife was found to be penetrating the temporal lobe, neighboring the intracavernous portion of the carotid artery. The patient was successfully managed in a conservative way. No abnormalities were seen at 12 months of follow-up. Dealing with penetrating head injuries is a usual condition in neurosurgical practice. Some situations are though really challenging, especially when the offending object is still in place, with a close connection to vital structures. This clinical reports an unusual penetrating head injury, highlighting the importance of careful radiographic evaluation and trying to discuss clear management options.
[Mh] Termos MeSH primário: Traumatismos Cranianos Penetrantes/terapia
Ferimentos Perfurantes/terapia
Zigoma/lesões
[Mh] Termos MeSH secundário: Traumatismos Cranianos Penetrantes/diagnóstico
Seres Humanos
Masculino
Meia-Idade
Tomografia Computadorizada por Raios X
Ferimentos Perfurantes/diagnóstico
Zigoma/diagnóstico por imagem
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:D
[Da] Data de entrada para processamento:161213
[St] Status:MEDLINE
[do] DOI:10.1097/SCS.0000000000003285


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[PMID]:27931948
[Au] Autor:Li XS; Yan J; Liu C; Luo Y; Liao XS; Yu L; Xiao SW
[Ad] Endereço:Department of Neurosurgery, The First Affiliated hospital of Guangxi Medical University, Nanning, Guangxi, China.
[Ti] Título:Nonmissile Penetrating Head Injuries: Surgical Management and Review of the Literature.
[So] Source:World Neurosurg;98:873.e9-873.e25, 2017 Feb.
[Is] ISSN:1878-8769
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Nonmissile penetrating head injuries (NPHIs) in the civilian population are rare but potentially fatal. Although numerous cases have been reported in the literature, the surgical management of such injuries is still ambiguous, especially with development of surgical techniques. Here, we report 5 cases of NPHIs managed with different surgical techniques and review the literature on surgical treatment of these injuries to outline the appropriate management for these patients from a neurosurgical perspective. METHODS: We retrospectively reviewed 5 cases of NPHIs managed surgically in our department. The clinical data were collected, including cause, type of objects, way of penetration, initial clinical evaluation, imaging, surgical intervention, postoperative care, complication, follow-up, and outcome. In addition, a systematic review of the literature was performed in the PubMed database to search for articles on surgical treatment of these injuries. RESULTS: These 5 cases were caused by twisted steel bar, electric welding rod, and sewing needle, respectively. Preoperative imaging, including computed tomography, magnetic resonance imaging, and digital subtraction angiography, was selectively performed to assist the operative plan. Foreign objects were removed surgically in all cases. Postoperative prophylactic administration of antibiotics and anticonvulsants was used to prevent infectious and epileptic complications. Most of the patients achieved a better outcome except for one. CONCLUSIONS: NPHIs can be fatal but they can be managed with satisfactory results by proper preoperative imaging evaluation, rapid appropriate surgical management, and accurate postoperative care. Personalized surgical intervention should be undertaken depending on the mechanism and extent of the NPHI.
[Mh] Termos MeSH primário: Corpos Estranhos/cirurgia
Traumatismos Cranianos Penetrantes/cirurgia
Procedimentos Neurocirúrgicos/métodos
[Mh] Termos MeSH secundário: Adulto
Angiografia Digital
Pré-Escolar
Feminino
Corpos Estranhos/complicações
Traumatismos Cranianos Penetrantes/complicações
Traumatismos Cranianos Penetrantes/diagnóstico por imagem
Seres Humanos
Imagem por Ressonância Magnética
Masculino
Meia-Idade
PubMed/estatística & dados numéricos
Estudos Retrospectivos
Tomografia Computadorizada por Raios X
Resultado do Tratamento
Adulto Jovem
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170915
[Lr] Data última revisão:
170915
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161210
[St] Status:MEDLINE



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