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  1 / 2082 MEDLINE  
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[PMID]:29402251
[Au] Autor:Kim JY; Lee JH; Lee CS; Lee SC
[Ad] Endereço:Department of Ophthalmology, The Institute of Vision Research, Yonsei University College of Medicine, Yonsei-ro 50-1, Seodaemun-gu, Seoul, South Korea.
[Ti] Título:Varicella zoster virus-associated Chorioretinitis: a case report.
[So] Source:BMC Ophthalmol;18(1):28, 2018 Feb 05.
[Is] ISSN:1471-2415
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Chorioretinitis is an unusual form of varicella zoster virus (VZV)-associated uveitis, and no report has described VZV-associated chorioretinitis using serial optical coherence tomography (OCT) images obtained during the course of resolution. CASE PRESENTATION: A 61-year-old woman presented with acute, unilateral vision loss in her right eye. Her visual acuity was count fingers in the right eye and 16/20 in the left eye, and she exhibited skin vesicles on her right forehead. Slit lamp biomicroscopy, funduscopy, OCT, and intraocular fluid analysis were performed. The right eye exhibited multiple inflammatory lesions at the posterior pole, macular edema, and disc swelling on the fundus examination. OCT revealed predominant involvement of the choroid and the retinal pigment epithelium (RPE). Intraocular fluid analysis showed positivity for VZV. The patient was admitted and treated with intravenous acyclovir. Additional oral prednisolone was used to reduce the inflammatory reaction. After 2 weeks of treatment with acyclovir, the lesion resolved, with undulation of the RPE. Her final visual acuity was 20/20. CONCLUSIONS: VZV-associated posterior uveitis may present as multifocal chorioretinitis. Intraocular fluid analysis is important to detect an infectious origin.
[Mh] Termos MeSH primário: Coriorretinite/virologia
Infecções Oculares Virais/virologia
Herpesvirus Humano 3/isolamento & purificação
Uveíte Posterior/virologia
Infecção pelo Vírus da Varicela-Zoster/virologia
[Mh] Termos MeSH secundário: Aciclovir/uso terapêutico
Administração Oral
Antivirais/uso terapêutico
Coriorretinite/diagnóstico
Coriorretinite/tratamento farmacológico
Terapia Combinada
Infecções Oculares Virais/diagnóstico
Infecções Oculares Virais/tratamento farmacológico
Feminino
Angiofluoresceinografia
Glucocorticoides/uso terapêutico
Seres Humanos
Meia-Idade
Prednisolona/uso terapêutico
Tomografia de Coerência Óptica
Uveíte Posterior/diagnóstico
Uveíte Posterior/tratamento farmacológico
Infecção pelo Vírus da Varicela-Zoster/diagnóstico
Infecção pelo Vírus da Varicela-Zoster/tratamento farmacológico
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antiviral Agents); 0 (Glucocorticoids); 9PHQ9Y1OLM (Prednisolone); X4HES1O11F (Acyclovir)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180216
[Lr] Data última revisão:
180216
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180207
[St] Status:MEDLINE
[do] DOI:10.1186/s12886-018-0696-3


  2 / 2082 MEDLINE  
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[PMID]:28465249
[Au] Autor:Pichi F; Sarraf D; Arepalli S; Lowder CY; Cunningham ET; Neri P; Albini TA; Gupta V; Baynes K; Srivastava SK
[Ad] Endereço:Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates; Cole Eye Institute, Cleveland Clinic, Cleveland, OH, USA. Electronic address: ilmiticopicchio@gmail.com.
[Ti] Título:The application of optical coherence tomography angiography in uveitis and inflammatory eye diseases.
[So] Source:Prog Retin Eye Res;59:178-201, 2017 Jul.
[Is] ISSN:1873-1635
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Since its introduction in the early 1990s, optical coherence tomography (OCT) has evolved in resolution and technological advances, and in recent years its initial application of assessing the morphology of a tissue has been implemented by the study of its functional blood flow, through optical coherence tomography angiography (OCTA). This novel technique details capillary networks by comparing the amount of light returned from static and moving targets without the need for intravenous dye administration. While this imaging modality has been used for various ocular conditions, the application OCTA to uveitis conditions remains sparse. This review aims to establish the basis of OCTA and its current application to ocular inflammatory disorders, with an emphasis on monitoring progression and response to treatment, as well as predicting visual complications. In particular, this review explores the use of OCTA in iris vessel dilation seen in various forms of iritis, as a predictive factor for further episodes of inflammation. OCTA can also depict ischemia in the deep plexus layers of the retina and identify true choroicapillaris ischemia in cases of placoid diseases or masking of the indocyanine green dye, as in multiple evanescent white dot syndrome. In addition, OCTA can depict neovascularization in granulomatous disease of the retina or choroid not previously depicted with previous imaging methods. While OCTA provides several advancements in the imaging, management and prognosis of uveitis diseases, we emphasize that further studies are required to fully understand its application to these conditions.
[Mh] Termos MeSH primário: Coriorretinite/diagnóstico
Angiofluoresceinografia/métodos
Vasos Retinianos/patologia
Tomografia de Coerência Óptica/métodos
Uveíte/diagnóstico
[Mh] Termos MeSH secundário: Fundo de Olho
Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180202
[Lr] Data última revisão:
180202
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170504
[St] Status:MEDLINE


  3 / 2082 MEDLINE  
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[PMID]:28470437
[Au] Autor:Garcia-Garcia O; Jordan-Cumplido S; Subira-Gonzalez O; Garcia-Bru P; Arias L; Caminal-Mitjana JM
[Ad] Endereço:Ophthalmology Department, University Hospital of Bellvitge, Hospitalet de Llobregat, Barcelona, Spain. 23221ogg@gmail.com.
[Ti] Título:Feasibility of swept-source OCT for active birdshot chorioretinopathy.
[So] Source:Graefes Arch Clin Exp Ophthalmol;255(8):1493-1502, 2017 Aug.
[Is] ISSN:1435-702X
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:PURPOSE: To assess the feasibility of swept-source optical coherence tomography (SS-OCT) for clinical follow-up of patients with birdshot chorioretinopathy (BC). METHODS: Prospective longitudinal, observational, 12-month case-control study in a tertiary care center. The study population included 12 patients (24 eyes) diagnosed with BC and 21 age- and sex-matched healthy controls (42 eyes). The macular areas in both affected and healthy eyes were prospectively analyzed with SS-OCT at 1050 nm, using 2D 12.0-mm radial and horizontal scans and the 3D raster scan protocol (12.0 × 9.0 mm). Anatomical and structural abnormalities, as well as retinal and choroidal thickness (measured automatically), were evaluated and compared with visual field (VF) testing and indocyanine green angiography (ICGA). RESULTS: The most common qualitative abnormalities in the retina were thinning/loss of architecture and outer retinal hyperreflective foci, and in the choroid they were focal depigmentation, thinning/absence of Sattler's layer, generalized thinning, and hyperreflective foci. The most significant changes in the retina from baseline to the 12-month follow-up were decreases in intraretinal cysts, subretinal fluid, and hyaloid thickening. In the choroid, focal depigmentation decreased significantly, while vascular pattern loss increased. Compared to the healthy volunteers, patients with BC had thinner choroids and retinas at both baseline and study end. Retinal thickness decreased significantly in BC patients over the 12-month study period, but choroidal thickness remained unchanged. Findings from ICGA, VF, and SS-OCT were perfectly correlated in most (≈ 60%) patients. CONCLUSIONS: SS-OCT is a non-invasive, rapid method of assessing choroidal and retinal changes in patients with birdshot disease. This technique provides a simple method of monitoring the course of the disease that can be used to complement conventional tests.
[Mh] Termos MeSH primário: Coriorretinite/diagnóstico
Corioide/patologia
Retina/patologia
Tomografia de Coerência Óptica/métodos
Acuidade Visual
[Mh] Termos MeSH secundário: Adulto
Idoso
Estudos de Casos e Controles
Estudos de Viabilidade
Feminino
Angiofluoresceinografia
Seguimentos
Fundo de Olho
Seres Humanos
Masculino
Meia-Idade
Estudos Prospectivos
Fatores de Tempo
[Pt] Tipo de publicação:JOURNAL ARTICLE; OBSERVATIONAL STUDY
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171128
[Lr] Data última revisão:
171128
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170505
[St] Status:MEDLINE
[do] DOI:10.1007/s00417-017-3655-4


  4 / 2082 MEDLINE  
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[PMID]:28451757
[Au] Autor:Semécas R; Mauget-Faÿsse M; Aptel F; Mailhac A; Salmon L; Vasseur V; Bouillet L; Chiquet C
[Ad] Endereço:Department of Ophthalmology, University Hospital, CS10217, Grenoble, F-38043, France.
[Ti] Título:Analysis of autofluorescence pattern in birdshot chorioretinopathy.
[So] Source:Graefes Arch Clin Exp Ophthalmol;255(7):1333-1339, 2017 Jul.
[Is] ISSN:1435-702X
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:PURPOSE: To characterize and correlate the different patterns of fundus autofluorescence (FAF) in patients with birdshot chorioretinopathy (BSCR), with functional and anatomical parameters. METHODS: Twenty-one BSCR patients were prospectively studied in 2013 and 2014. Each patient underwent visual acuity (VA) and visual field (SITA standard 30.2) testing as well as fluorescein and indocyanine green angiography, spectral-domain optical coherence tomography (SD-OCT) B scan, enhanced depth imaging (EDI), and fundus autofluorescence (FAF) imaging. The disease was classified as active, chronic, or quiescent. RESULTS: The patients' mean age was 60.3 ± 9.2 years and 60% were female. Disease duration was 5.7 ± 3.7 years. Autofluorescence imaging showed punctiform hyper-FAF spots in 23 out of the 29 eyes (79%), which was significantly associated with a greater visual field mean deviation (-7 ± 7 versus -3 ± 2 dB, p = 0.04). Hypo-FAF was defined as peripapillary (n = 25; 86.2%), macular (n = 10; 34.5%), lichenoid (n = 17; 58.6%), and/or diffuse (n = 13; 44.8%). Lichenoid hypo-FAF was significantly associated with worse VA (0.18 ± 0.24 vs. 0.05 ± 0.07 LogMAR, p = 0.04). Macular hypo-FAF was associated with a history of macular edema (62.5%; p = 0.06). Diffuse hypo-FAF was observed more frequently (p = 0.01) in chronic disease (66.7%) than in active (0%) or quiescent disease (27.3%). CONCLUSIONS: Autofluorescence analysis in BRSC patients contributes to evaluating disease activity and could be useful to guide follow-up and treatment.
[Mh] Termos MeSH primário: Coriorretinite/diagnóstico
Corioide/patologia
Angiofluoresceinografia/métodos
Retina/patologia
Tomografia de Coerência Óptica/métodos
[Mh] Termos MeSH secundário: Coriorretinite/fisiopatologia
Feminino
Fundo de Olho
Seres Humanos
Masculino
Meia-Idade
Estudos Prospectivos
Acuidade Visual
Campos Visuais
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171128
[Lr] Data última revisão:
171128
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170429
[St] Status:MEDLINE
[do] DOI:10.1007/s00417-017-3644-7


  5 / 2082 MEDLINE  
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[PMID]:29069031
[Au] Autor:Zhu J; Jiang Y; Shi Y; Zheng B; Xu Z; Jia W
[Ad] Endereço:aDepartment of Ophthalmology, The Affiliated Guangren Hospital of Xi'an Jiaotong University College of Medicine bDepartment of Otorhinolaryngology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
[Ti] Título:Clinical manifestations and treatment outcomes of syphilitic uveitis in HIV-negative patients in China: A retrospective case study.
[So] Source:Medicine (Baltimore);96(43):e8376, 2017 Oct.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Syphilitic chorioretinitis should be included in differential diagnosis of any form of ocular inflammation. A significantly higher proportion of human immunodeficiency virus (HIV)-positive patients with ocular syphilis as compared to HIV-negative cases have been reported in published studies. However, the clinical signs and symptoms are more insidious in HIV-negative patients who are easily misdiagnosed. We report a series of cases of ocular syphilis and describe the clinical manifestations and treatment outcomes of syphilitic chorioretinitis in HIV-negative patients in China.This was a retrospective case series study. The clinical records of patients with syphilis chorioretinitis were reviewed. Demographic information and findings of fundus fluorescein angiography (FFA), indocyanine green angiography (ICGA), and spectral domain optical coherence tomography (SD-OCT) were analyzed. All patients received the standard treatment. Ophthalmology examination and laboratory evaluation were repeated every 3 months. All changes were recorded. The treatment was considered successful if the patients had no inflammation in both eyes and rapid plasma reagin titer was negative after therapy.The study examined 41 eyes of 28 HIV-negative patients. The main complaints were blurry vision, floaters, and visual field defect. Twenty-seven eyes presented with panuveitis, and all had posterior involvement, including uveitis, vasculitis, chorioretinitis, and optic neuritis. The most common manifestations were uveitis and retinal vasculitis. Disc hyperfluorescence and persistent dark spots were the most common findings on FFA and ICGA. The ill-defined inner segment/outer segment junction was the most frequent manifestation on SD-OCT. Patients were diagnosed with syphilitic uveitis based on positive serological tests. Best-corrected visual acuity (BCVA) was improved in 34 eyes after treatment. Eleven patients were misdiagnosed before serological tests were performed. The delay in treatment led to long-standing cystoid macular edema and optic neuropathy, which were associated with poor BCVA (P = .037).The common manifestations of syphilitic chorioretinitis were uveitis, retinal vasculitis, and optic neuritis. Further diagnosis should be prompted by FFA, ICGA, and SD-OCT when ocular manifestation is suspected. The standard treatment for neurosyphilis was effective. If patients are presumed to be in low-risk groups such as HIV-negative, delays in diagnosis, and therapy may be likely. It is necessary to reiterate the importance of including syphilis uveitis as a differential diagnosis for any form of ocular inflammations, especially posterior uveitis and optic neuropathy.
[Mh] Termos MeSH primário: Coriorretinite/microbiologia
Infecções Oculares Bacterianas/complicações
Sífilis/complicações
Uveíte/microbiologia
[Mh] Termos MeSH secundário: Adulto
Idoso
Antibacterianos/uso terapêutico
China
Coriorretinite/tratamento farmacológico
Infecções Oculares Bacterianas/tratamento farmacológico
Infecções Oculares Bacterianas/microbiologia
Feminino
Angiofluoresceinografia
Seres Humanos
Masculino
Meia-Idade
Neurite Óptica/tratamento farmacológico
Neurite Óptica/microbiologia
Vasculite Retiniana/tratamento farmacológico
Vasculite Retiniana/microbiologia
Estudos Retrospectivos
Sífilis/tratamento farmacológico
Sífilis/microbiologia
Tomografia de Coerência Óptica
Resultado do Tratamento
Uveíte/tratamento farmacológico
Acuidade Visual
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Bacterial Agents)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171123
[Lr] Data última revisão:
171123
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171026
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000008376


  6 / 2082 MEDLINE  
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[PMID]:28810044
[Au] Autor:Khairallah M; Kahloun R; Gargouri S; Jelliti B; Sellami D; Ben Yahia S; Feki J
[Ti] Título:Swept-Source Optical Coherence Tomography Angiography in West Nile Virus Chorioretinitis and Associated Occlusive Retinal Vasculitis.
[So] Source:Ophthalmic Surg Lasers Imaging Retina;48(8):672-675, 2017 Aug 01.
[Is] ISSN:2325-8179
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:A 65-year-old man with diabetes and a history of fever of unknown origin 2 weeks earlier complained of sudden decreased vision in the left eye. The patient was diagnosed with bilateral West Nile virus (WNV) chorioretinitis associated with occlusive retinal vasculitis in the left eye. Swept-source optical coherence tomography angiography (SS-OCTA) of the left eye showed extensive, well-delineated, hypointense non-perfusion areas and perifoveal capillary arcade disruption in the superficial capillary plexus, as well as larger non-perfusion areas, capillary rarefaction, and diffuse capillary network attenuation and disorganization in the deep capillary plexus. OCTA may be a valuable tool for noninvasively assessing occlusive retinal vasculitis associated with WNV infection. It allows an accurate detection and precise delineation of areas of retinal capillary nonperfusion in both the superficial and deep capillary plexuses. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:672-675.].
[Mh] Termos MeSH primário: Coriorretinite/diagnóstico
Corioide/patologia
Infecções Oculares Virais/diagnóstico
Angiofluoresceinografia/métodos
Retina/patologia
Tomografia de Coerência Óptica/métodos
Febre do Nilo Ocidental/diagnóstico
[Mh] Termos MeSH secundário: Idoso
Anticorpos Antivirais/imunologia
Coriorretinite/virologia
Diagnóstico Diferencial
Infecções Oculares Virais/virologia
Fundo de Olho
Seres Humanos
Masculino
Febre do Nilo Ocidental/virologia
Vírus do Nilo Ocidental/imunologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antibodies, Viral)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170929
[Lr] Data última revisão:
170929
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170816
[St] Status:MEDLINE
[do] DOI:10.3928/23258160-20170802-11


  7 / 2082 MEDLINE  
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[PMID]:28810039
[Au] Autor:Wang JC; Laíns I; Sobrin L; Miller JB
[Ti] Título:Distinguishing White Dot Syndromes With Patterns of Choroidal Hypoperfusion on Optical Coherence Tomography Angiography.
[So] Source:Ophthalmic Surg Lasers Imaging Retina;48(8):638-646, 2017 Aug 01.
[Is] ISSN:2325-8179
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND AND OBJECTIVE: To compare patterns of choroidal hypoperfusion in white dot syndromes (WDS) using optical coherence tomography angiography (OCTA). PATIENTS AND METHODS: Consecutive patients with WDS were imaged with either the Zeiss AngioPlex OCT Angiography (Carl Zeiss AG, Oberkochen, Germany) or the AngioVue OCT Angiography (Optovue, Fremont, CA) from February to November 2016. Four patients with acute posterior multifocal placoid pigment epitheliopathy (APMPPE), birdshot chorioretinopathy (BCR), presumed ocular histoplasmosis syndrome (POHS), and multiple evanescent white dot syndrome (MEWDS) were selected. This study was approved by the institutional review board at Massachusetts Eye and Ear. RESULTS: Unique patterns of choroidal hypoperfusion were observed. In POHS and MEWDS, areas of choroidal hypoperfusion correlated well with clinically observed pathology, but in APMPPE and BCR, they were more widespread. CONCLUSION: OCTA can identify different patterns of choroidal hypoperfusion in APMPPE, BCR, POHS, and MEWDS, which appears to be a shared feature of WDS. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:638-646.].
[Mh] Termos MeSH primário: Coriorretinite/diagnóstico
Corioide/patologia
Angiofluoresceinografia/métodos
Fluxo Sanguíneo Regional/fisiologia
Retina/patologia
Vasos Retinianos/patologia
Tomografia de Coerência Óptica/métodos
[Mh] Termos MeSH secundário: Adulto
Corioide/irrigação sanguínea
Diagnóstico Diferencial
Feminino
Seguimentos
Fundo de Olho
Seres Humanos
Masculino
Meia-Idade
Estudos Retrospectivos
Síndrome
Acuidade Visual
Adulto Jovem
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170929
[Lr] Data última revisão:
170929
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170816
[St] Status:MEDLINE
[do] DOI:10.3928/23258160-20170802-06


  8 / 2082 MEDLINE  
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[PMID]:28800648
[Au] Autor:Böni C; Thorne JE; Spaide RF; Ostheimer TA; Sarraf D; Levinson RD; Goldstein DA; Rifkin LM; Vitale AT; Jaffe GJ; Holland GN
[Ad] Endereço:Ocular Inflammatory Disease Center, UCLA Stein Eye Institute and the Department of Ophthalmology, David Geffen School of Medicine at UCLA, Los Angeles, California, United States.
[Ti] Título:Fundus Autofluorescence Findings in Eyes With Birdshot Chorioretinitis.
[So] Source:Invest Ophthalmol Vis Sci;58(10):4015-4025, 2017 Aug 01.
[Is] ISSN:1552-5783
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Purpose: The purpose of this study was to describe fundus autofluorescence (FAF) findings in eyes with birdshot chorioretinitis (BSCR) and to compare findings to demographic, medical, and clinical characteristics. Methods: In this multicenter, prospective, cross-sectional study, 172 eyes (86 patients) with BSCR were investigated. Participants underwent a standardized evaluation including collection of demographic data, ophthalmic and treatment history, and ophthalmologic examination. Using a standardized protocol, hypo- and hyperautofluorescence in macular and extramacular regions and specific patterns of abnormal FAF could be scored for 167 eyes. Images were scored by two independent, masked graders. Measures of visual function included best-corrected visual acuity (BCVA), contrast sensitivity (CS), color vision, and Humphrey visual field mean deviation (HVF-MD). Results: Any abnormal FAF finding was observed in 132 eyes (79.0%); macular abnormalities were observed in 84 eyes (49.1%). The most common findings were peripapillary confluent hypoautofluorescence (122 eyes [73.1%]); extramacular granular hypoautofluorescence (100 eyes [59.9%]); and macular granular hypoautofluorescence (67 eyes [40.1%]). Confluent hypoautofluorescence was related to longer median disease duration (8.7 years) than granular hypoautofluorescence (7.9 years) or hyperautofluorescence (5.6 years). Macular confluent hypoautofluorescence was associated with BCVA ≤20/25 (odds ratio [OR] = 7.83, P = 0.007), BCVA ≤20/50 (OR = 4.94, P = 0.002), and abnormal CS (OR = 4.56, P = 0.009). Presence of macular or extramacular hypoautofluorescence was related to HVF-MD ≤-3 dB (OR = 2.43, P = 0.01 and OR = 2.89, P = 0.003, respectively). Conclusions: In this large cohort, various FAF abnormalities were found, indicating that disorders of the retinal pigment epithelium are features of BSCR. Abnormal FAF is a marker of visual dysfunction in the disease.
[Mh] Termos MeSH primário: Coriorretinite/diagnóstico
Imagem Óptica
Epitélio Pigmentado da Retina/patologia
[Mh] Termos MeSH secundário: Coriorretinite/fisiopatologia
Visão de Cores/fisiologia
Estudos Transversais
Feminino
Angiofluoresceinografia
Fundo de Olho
Seres Humanos
Masculino
Meia-Idade
Estudos Prospectivos
Epitélio Pigmentado da Retina/fisiopatologia
Tomografia de Coerência Óptica
Acuidade Visual/fisiologia
Testes de Campo Visual
Campos Visuais/fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; MULTICENTER STUDY
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170821
[Lr] Data última revisão:
170821
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170812
[St] Status:MEDLINE
[do] DOI:10.1167/iovs.17-21897


  9 / 2082 MEDLINE  
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[PMID]:28795959
[Au] Autor:de Paula Freitas B; Ventura CV; Maia M; Belfort R
[Ad] Endereço:aVision Institute, Department of Ophthalmology, Paulista Medical School, Federal University of São Paulo, São Paulo bDepartment of Ophthalmology, Hospital Geral Roberto Santos, Salvador cDepartment of Ophthalmology, Altino Ventura Foundation dDepartment of Ophthalmology, HOPE Eye Hospital, Recife, Pernambuco, Brazil.
[Ti] Título:Zika virus and the eye.
[So] Source:Curr Opin Ophthalmol;28(6):595-599, 2017 Nov.
[Is] ISSN:1531-7021
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PURPOSE OF REVIEW: The aim of this study was to review the ocular findings related to the Zika virus (ZIKV) based on the main studies published to date, describe the patterns of the lesions and risk factors, and identify the public health implications and scientific importance of this emerging disease. RECENT FINDINGS: In most studies, the ZIKV seems related to congenital ocular lesions and most mothers reported mild symptoms during the first pregnancy trimester. Five fundus patterns were seen most often: macular chorioretinal atrophy, chorioretinal atrophy elsewhere, focal pigmentary changes in the macular region, optic nerve abnormalities and combined types. A few studies have suggested that the ZIKV might damage the anterior segment of these babies' eyes. Few reports have described the ocular complications seen in adults during the acute infection, including conjunctivitis, iridocyclitis and chorioretinitis. SUMMARY: Infants with congenital Zika syndrome might have vision-threatening fundus abnormalities. Although the full spectrum of ocular lesions caused by the ZIKV infection is not yet determined, a distinctive new disease has been observed. Recognition of these lesions by ophthalmologists can help ensure appropriate etiologic evaluation and clinical investigation to define the range of anomalies in an affected infant and determine essential follow-up and ongoing care.
[Mh] Termos MeSH primário: Doenças Transmissíveis Emergentes
Infecções Oculares Virais/diagnóstico
Complicações Infecciosas na Gravidez/diagnóstico
Infecção pelo Zika virus/diagnóstico
Zika virus
[Mh] Termos MeSH secundário: Coriorretinite/diagnóstico
Coriorretinite/virologia
Infecções Oculares Virais/virologia
Feminino
Seres Humanos
Doenças do Nervo Óptico/diagnóstico
Doenças do Nervo Óptico/virologia
Gravidez
Complicações Infecciosas na Gravidez/virologia
Infecção pelo Zika virus/virologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171016
[Lr] Data última revisão:
171016
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170811
[St] Status:MEDLINE
[do] DOI:10.1097/ICU.0000000000000420


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[PMID]:28494563
[Au] Autor:Hu F; Wang XN; Cao XS; Peng XY
[Ad] Endereço:Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Sciences Key Lab., Beijing 100730, China.
[Ti] Título:[The clinical manifestations and imaging characteristics of acute syphilitic posterior placoid chorioretinitis].
[So] Source:Zhonghua Yan Ke Za Zhi;53(5):352-357, 2017 May 11.
[Is] ISSN:0412-4081
[Cp] País de publicação:China
[La] Idioma:chi
[Ab] Resumo:To investigate the clinical manifestations and imaging characteristics of acute syphilitic posterior placoid chorioretinitis (ASPPC). Retrospective study of 10 patients diagnosed ASPPC in the Department of Ophthalmology, Beijing Tongren Hospital from 2011 to 2016, including 6 males (10 eyes involved) and 4 females (8 eyes involved) with an age of (43.4±11.6) years (range, 26-60 years). Their clinical manifestations and imaging characteristics were summarized. All 10 ASPPC patients complained about the reduction of visual acuity, and the majority of them had both eyes involved. The initial visual acuity ranged from finger count to 0.8, with an average of 0.4 and a median visual acuity of 0.3. The intraocular pressure was in the normal range. The inflammation of anterior chamber occurred in only one patient (1/10). The lesions were located at the posterior pole as shown on fundus photographs. There are six placoid lesions, four yellowish massive lesions and seven mixed lesions (placoid and yellowish massive lesions). Partial or whole disappearance, abnormality and opacity of the ellipsoid layer, retinal pigment epithelial (RPE) nodules, and cells in the vitreous body were observed by optical coherence tomography. There were partial detachment between the neuronal retina and RPE layer with fine-sand like hypereflective dots. The lesion size and morphology on autofluorescence (AF), fundus fluorescence angiography (FFA) and indocyanine green angiography (ICG) were almost consistent with those on fundus photography. The lesions were hyperautofluorescent in a placoid or massive shape. The lesions on FFA showed slight hyperfluorescence with unclear edges from the venous phase, and the fluorescence increased with the time and leaked in the late phase. Vascular walls showed blood staining in the late phase. The lesions on ICG showed hypofluorescence with hyperfluorescence and hypofluorescence dots like fine needles in the middle and late phases. ASPPC mainly occurs among the young adults without gender difference. The characteristic is the contradiction between sever clinical symptoms and slight signs on the fundus. The lesion area shown on fundus photography, FFA, ICG and AF is consistent, as well as injuries of the ellipsoid layer, RPE nodules and cells in the vitreous body. The above manifestations and imaging characteristics of ASPPC are significant for the diagnosis and differential diagnosis. - .
[Mh] Termos MeSH primário: Coriorretinite/complicações
Infecções Oculares Bacterianas/complicações
Sífilis/complicações
Acuidade Visual
[Mh] Termos MeSH secundário: Doença Aguda
Adulto
Coriorretinite/diagnóstico por imagem
Coriorretinite/microbiologia
Infecções Oculares Bacterianas/diagnóstico por imagem
Infecções Oculares Bacterianas/microbiologia
Feminino
Angiofluoresceinografia
Fundo de Olho
Seres Humanos
Masculino
Meia-Idade
Retina
Estudos Retrospectivos
Sífilis/diagnóstico por imagem
Tomografia de Coerência Óptica
Corpo Vítreo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170831
[Lr] Data última revisão:
170831
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170512
[St] Status:MEDLINE
[do] DOI:10.3760/cma.j.issn.0412-4081.2017.05.007



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