[PMID]: | 27454594 |
[Au] Autor: | Papadakis GZ; Millo C; Sadowski SM; Bagci U; Patronas NJ |
[Ad] Endereço: | From the *Radiology and Imaging Sciences, Warren Grant Magnuson Clinical Center, †Division of Nuclear Medicine, RADIS, Clinical Center, and ‡Endocrine Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD; §Endocrine and Thoracic Surgery, University Hospitals of Geneva, Geneva, Switzerland; and ∥Center for Research in Computer Vision, Electrical and Computer Science Department, University of Central Florida, Orlando, FL. |
[Ti] Título: | Epididymal Cystadenomas in von Hippel-Lindau Disease Showing Increased Activity on 68Ga DOTATATE PET/CT. |
[So] Source: | Clin Nucl Med;41(10):781-2, 2016 Oct. |
[Is] ISSN: | 1536-0229 |
[Cp] País de publicação: | United States |
[La] Idioma: | eng |
[Ab] Resumo: | von Hippel-Lindau (VHL) disease is a familial cancer syndrome characterized by the development of a variety of malignant and benign tumors, including epididymal cystadenomas. We report a case of a VHL patient with bilateral epididymal cystadenomas who was evaluated with Ga DOTATATE PET/CT, showing intensely increased activity (SUVmax, 21.6) associated with the epididymal cystadenomas, indicating cell-surface overexpression of somatostatin receptors. The presented case supports the usefulness of somatostatin receptor imaging using Ga DOTA-conjugated peptides for detection and follow-up of VHL manifestations, as well as surveillance of asymptomatic gene carriers. |
[Mh] Termos MeSH primário: |
Cistadenoma/diagnóstico por imagem Tomografia Computadorizada com Tomografia por Emissão de Pósitrons Espermatocele/diagnóstico por imagem Doença de von Hippel-Lindau/diagnóstico por imagem
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[Mh] Termos MeSH secundário: |
Seres Humanos Masculino Meia-Idade Compostos Organometálicos Compostos Radiofarmacêuticos
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[Pt] Tipo de publicação: | CASE REPORTS; JOURNAL ARTICLE |
[Nm] Nome de substância:
| 0 (Organometallic Compounds); 0 (Radiopharmaceuticals); 9L17Y0H71P (dotatate gallium ga-68) |
[Em] Mês de entrada: | 1701 |
[Cu] Atualização por classe: | 171031 |
[Lr] Data última revisão:
| 171031 |
[Sb] Subgrupo de revista: | IM |
[Da] Data de entrada para processamento: | 160726 |
[St] Status: | MEDLINE |
[do] DOI: | 10.1097/RLU.0000000000001314 |
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