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[PMID]:29376599
[Au] Autor:Polyakov NV; Keshishev NG; Gurbanov SS; Grigoreva MV; Serebryannyi SA; Kazachenko AV; Alekseev BY
[Ad] Endereço:N.A. Lopatkin Scientific Research Institute of Urology and Interventional Radiology Branch of National Medical Research Radiological Center of the Ministry of Health of Russia, Moscow, Russia.
[Ti] Título:[Effectiveness of laparoscopic repair of primary strictures of ureteropelvic junction].
[So] Source:Urologiia;(6):72-75, 2017 Dec.
[Is] ISSN:1728-2985
[Cp] País de publicação:Russia (Federation)
[La] Idioma:rus
[Ab] Resumo:AIM: To evaluate the effectiveness of laparoscopic repair of primary strictures of ureteropelvic junction (UPJ) depending on baseline renal function of the ipsilateral kidney. MATERIALS AND METHODS: The study analyzed results of 134 patients (78 women and 56 men, age from 18 to 56 years) who underwent various types of laparoscopic repair of the UPJ stricture from 2012 to 2015. Depending on the surgical technique all patients were divided into three groups: group 1 (n=34) underwent spiral flap technique by Culp and DeWeerd, group 2 (n=59) - Anderson-Hynes pyeloplasty and group 3 (n=41) had antevasal dismembered pyeloplasty. All interventions ended with internal ureteral stenting for up to 6-8 weeks. Also, all patients were divided into three subgroups, depending on the degree of renal function deficiency - less than 25%, 25-50%, and 51-75%. Treatment effectiveness criteria included the following parameters: complete relief of the pain syndrome, a decrease in the degree of pyeloectasia, stabilization or improvement of the functional state of the renal parenchyma (according to radioisotope renography), and the absence of recurrence of the UPJ stricture. RESULTS: The overall effectiveness of UPJ laparoscopic reconstruction was 94.7% (127 of 134). The effectiveness of the treatment was independent of the surgical technique, the initial thickness of the renal parenchyma and the degree of PCS dilatation. There was an inverse correlation between the treatment effectiveness the degree of kidney function deficiency. CONCLUSION: In patients with hydronephrosis secondary to UPJ stricture, the effectiveness of surgical treatment is mainly determined by its timeliness. The best treatment results were observed in patients with better renal function. The degree of renal function deficiency should be considered the main prognostic factor for the effectiveness of the forthcoming operation.
[Mh] Termos MeSH primário: Pelve Renal/cirurgia
Laparoscopia/métodos
Ureter/cirurgia
Estreitamento Uretral/terapia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Feminino
Seres Humanos
Pelve Renal/patologia
Masculino
Meia-Idade
Ureter/fisiologia
Estreitamento Uretral/patologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180130
[St] Status:MEDLINE


  2 / 4181 MEDLINE  
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[PMID]:28749039
[Au] Autor:Mukhtar BMB; Spilotros M; Malde S; Greenwell TJ
[Ad] Endereço:Department of Urology, University College London Hospital at Westmoreland Street, London, UK.
[Ti] Título:Ventral-onlay buccal mucosa graft substitution urethroplasty for urethral stricture in women.
[So] Source:BJU Int;120(5):710-716, 2017 11.
[Is] ISSN:1464-410X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To present our outcomes of ventral-onlay buccal mucosa graft (BMG) substitution urethroplasty in treating female urethral stricture (FUS). PATIENTS AND METHODS: We conducted a review of a prospectively collected database of 22 consecutive women (median [range] age 50 [34-72] years) with urethral stricture who underwent ventral onlay BMG substitution urethroplasty after June 2012 and who had a minimum follow-up of 6 months (median 21.5, range 6-51 months). Data were analysed for stricture recurrence, change in median maximum urinary flow rate (Q ) and median post-void residual urine volume (PVR). Statistical analysis was performed using the Wilcoxon signed rank test, Student's t-test and the Mann-Whitney U-test. RESULTS: Freedom from stricture recurrence was achieved in 21/22 (95.5%) women. The median (range) Q significantly improved, increasing from 7 (3.5-11) to 18 (5-37) mL/s (P <0.05). The median (range) PVR was significantly reduced from 100 (0-300) to 15 (0-150) mL (P < 0.05). Short- and longer-term complication rates were low. One woman developed mild de novo stress urinary incontinence, which settled with conservative management by 6 months. CONCLUSIONS: Early and medium-term results indicate that ventral onlay BMG substitution urethroplasty is an excellent treatment for FUS that can avoid the need for the repeat procedures regularly required after traditional endoscopic management.
[Mh] Termos MeSH primário: Mucosa Bucal/cirurgia
Transplantes/cirurgia
Transplantes/transplante
Uretra/cirurgia
Estreitamento Uretral/cirurgia
Procedimentos Cirúrgicos Urológicos/métodos
[Mh] Termos MeSH secundário: Adulto
Idoso
Feminino
Seres Humanos
Meia-Idade
Complicações Pós-Operatórias
Estudos Prospectivos
Procedimentos Cirúrgicos Urológicos/efeitos adversos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:180305
[Lr] Data última revisão:
180305
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170728
[St] Status:MEDLINE
[do] DOI:10.1111/bju.13970


  3 / 4181 MEDLINE  
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[PMID]:29308838
[Au] Autor:Vasyutin IA; Lyundup AV; Viranov AZ; Butnaru DV; Kuznetsov SL
[Ti] Título:Urethra Reconstruction with Tissue-Engineering Technology.
[So] Source:Vestn Ross Akad Med Nauk;72(1):17-25, 2017.
[Is] ISSN:0869-6047
[Cp] País de publicação:Russia (Federation)
[La] Idioma:eng
[Ab] Resumo:Urethral stricture is a disease characterized by a pathological narrowing of the urethra. Treatment for this condition often requires surgery using autologous grafts (urethroplasty). It is common practice to use patient's own tissue like genital and extragenital skin, tunica vaginalis, buccal mucosa as a source of the graft. Alternative and safer approach is to use tissue-engineered graft created in a laboratory using patient's autologous cells and biocompatible matrix (scaffold). The article presents the up-to-date achievements in lab-created tissue-engineered graft, describes all components needed to build a tissue-engineered structure of the graft for urethroplasty, and summarizes authors' thoughts on advantages and disadvantages of various approaches to choose both cellular component and the matrix of future construction. The article reviews clinical studies conducted in the field of tissue engineering of the graft material for urethraplasty.
[Mh] Termos MeSH primário: Procedimentos Cirúrgicos Reconstrutivos
Engenharia Tecidual/métodos
Uretra/cirurgia
Estreitamento Uretral/cirurgia
Procedimentos Cirúrgicos Urológicos
[Mh] Termos MeSH secundário: Seres Humanos
Procedimentos Cirúrgicos Reconstrutivos/instrumentação
Procedimentos Cirúrgicos Reconstrutivos/métodos
Tecidos Suporte
Transplantes/classificação
Procedimentos Cirúrgicos Urológicos/instrumentação
Procedimentos Cirúrgicos Urológicos/métodos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180220
[Lr] Data última revisão:
180220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180109
[St] Status:MEDLINE
[do] DOI:10.15690/vramn771


  4 / 4181 MEDLINE  
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[PMID]:29406061
[Au] Autor:Kiechle JE; Chertack N; Gonzalez CM
[Ad] Endereço:Urology Institute, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, 11100 Euclid Avenue, Cleveland, OH 44106, USA.
[Ti] Título:Penile and Urethral Reconstructive Surgery.
[So] Source:Med Clin North Am;102(2):325-335, 2018 Mar.
[Is] ISSN:1557-9859
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Penile and urethral reconstructive surgical procedures are used to treat a variety of urologic diagnoses. Urethral stricture disease can lead to progressive lower urinary tract symptoms and may require multiple surgical procedures to improve patient's symptoms. Male stress urinary incontinence is associated with intrinsic sphincter deficiency oftentimes associated with radical prostatectomy. Men suffering from urethral stricture disease and stress urinary incontinence should be referred to a urologist because multiple treatment options exist to improve their quality of life.
[Mh] Termos MeSH primário: Pênis/cirurgia
Procedimentos Cirúrgicos Reconstrutivos/métodos
Uretra/cirurgia
Doenças Uretrais/cirurgia
[Mh] Termos MeSH secundário: Seres Humanos
Masculino
Encaminhamento e Consulta
Estreitamento Uretral/cirurgia
Incontinência Urinária por Estresse
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180208
[Lr] Data última revisão:
180208
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180207
[St] Status:MEDLINE


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[PMID]:29240338
[Ti] Título:Healthcare Costs Associated with Hydrophilic-Coated And Non-Coated Urinary Catheters for Intermittent Use In the United States.
[So] Source:Urol Nurs;36(5):233-42, 2016 Sep-Oct.
[Is] ISSN:1053-816X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:This health economic evaluation simulated a cohort to compare hydrophilic-coated to non-coated catheters for intermittent catheterization. By using a Markov model, lifetime costs and catheter-related complications were investigated. Results determined that the use of hydrophilic-coated catheters save money and reduce treatment-related complications.
[Mh] Termos MeSH primário: Bacteriemia/epidemiologia
Infecções Relacionadas a Cateter/epidemiologia
Epididimite/epidemiologia
Custos de Cuidados de Saúde
Estreitamento Uretral/epidemiologia
Cálculos da Bexiga Urinária/epidemiologia
Bexiga Urinaria Neurogênica/enfermagem
Cateterismo Urinário/métodos
Cateteres Urinários/economia
Infecções Urinárias/epidemiologia
[Mh] Termos MeSH secundário: Adulto
Idoso
Bacteriemia/economia
Infecções Relacionadas a Cateter/economia
Estudos de Coortes
Epididimite/economia
Feminino
Seres Humanos
Masculino
Cadeias de Markov
Meia-Idade
Modelos Econômicos
Autocuidado
Estados Unidos
Estreitamento Uretral/economia
Cálculos da Bexiga Urinária/economia
Cateterismo Urinário/instrumentação
Infecções Urinárias/economia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180123
[Lr] Data última revisão:
180123
[Sb] Subgrupo de revista:N
[Da] Data de entrada para processamento:171215
[St] Status:MEDLINE


  6 / 4181 MEDLINE  
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[PMID]:28953722
[Au] Autor:Massie JP; Morrison SD; Wilson SC; Crane CN; Chen ML
[Ad] Endereço:New York, N.Y.; Seattle, Wash.; and San Francisco, Calif. From the Hansjörg Wyss Department of Plastic Surgery, New York University Langone Medical Center; the Division of Plastic Surgery, Department of Surgery, University of Washington School of Medicine; and Brownstein and Crane Surgical Services.
[Ti] Título:Phalloplasty with Urethral Lengthening: Addition of a Vascularized Bulbospongiosus Flap from Vaginectomy Reduces Postoperative Urethral Complications.
[So] Source:Plast Reconstr Surg;140(4):551e-558e, 2017 Oct.
[Is] ISSN:1529-4242
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Phalloplasty with urethral lengthening is the procedure of choice for female-to-male transgender patients who desire an aesthetic phallus and standing micturition, but is associated with complications, including urethral stricture and fistula formation. Horizontal urethra construction can be accomplished with labia minora flaps covered with additional vascularized layers of vestibular tissue when vaginectomy is performed concomitantly with phalloplasty. However, vaginectomy is not a requisite step in phalloplasty, and some individuals may choose to retain their vagina. In these cases, extra layers of vascularized vestibular tissue are not used for horizontal urethra coverage. This study examined the effects of vaginectomy and the addition of extra layers of vascularized vestibular tissue on phalloplasty complication rates. METHODS: A single-center retrospective study of 224 patients who underwent phalloplasty with urethral lengthening was performed. Patients were sorted into vaginectomy and vaginal preservation cohorts and complication rates were assessed. RESULTS: Of 224 total phalloplasty patients, 215 underwent vaginectomy and nine underwent vaginal preservation. Urethral complications occurred in 27 percent of patients with vaginectomy and in 67 percent of patients with vaginal preservation (OR, 0.18; p = 0.02). Vaginectomy was associated with decreased urethral stricture (OR, 0.25; p = 0.047) and urethral fistula formation (OR, 0.13; p = 0.004). Non-urethra-related complications occurred in 15 percent of vaginectomy patients but were not statistically significant (OR, 3.37; p = 0.41). CONCLUSION: Vaginectomy is associated with a significant decrease in urethral stricture and fistula formation, most likely because vaginectomy affords additional horizontal urethroplasty suture line coverage of labia minora flaps with vascularized vestibular tissue. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, III.
[Mh] Termos MeSH primário: Pênis/cirurgia
Procedimentos Cirúrgicos Reconstrutivos/métodos
Retalhos Cirúrgicos/irrigação sanguínea
Uretra/cirurgia
Estreitamento Uretral/prevenção & controle
Procedimentos Cirúrgicos Urológicos/métodos
Vagina/cirurgia
[Mh] Termos MeSH secundário: Adulto
Feminino
Seres Humanos
Masculino
Complicações Pós-Operatórias/epidemiologia
Complicações Pós-Operatórias/prevenção & controle
Estudos Retrospectivos
Transexualismo/cirurgia
Resultado do Tratamento
Estados Unidos/epidemiologia
Estreitamento Uretral/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171012
[Lr] Data última revisão:
171012
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170928
[St] Status:MEDLINE
[do] DOI:10.1097/PRS.0000000000003697


  7 / 4181 MEDLINE  
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[PMID]:28845951
[Au] Autor:Zhivov AV; Reva IA; Tedeev RL; Pushkar DY
[Ad] Endereço:Department of Urology, A.I. Evdokimov MSUMD, Moscow, Russia.
[Ti] Título:[American urological association guideline for diagnosis and management of male urethral stricture 2016].
[So] Source:Urologiia;(3):127-136, 2017 Jul.
[Is] ISSN:1728-2985
[Cp] País de publicação:Russia (Federation)
[La] Idioma:rus
[Ab] Resumo:The article provides coverage of the main features of the American Urological Association (AUA) Guideline for the diagnosis and management of male urethral stricture published in 2016. Clinical guideline on this medical condition is published for the first time and is unique in the world of urology. The authors present their comments based on the accumulated experience of diagnosis and treatment of this urological condition.
[Mh] Termos MeSH primário: Guias de Prática Clínica como Assunto
Estreitamento Uretral/diagnóstico
Estreitamento Uretral/cirurgia
[Mh] Termos MeSH secundário: Seres Humanos
Masculino
Estados Unidos
Procedimentos Cirúrgicos Urológicos Masculinos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171109
[Lr] Data última revisão:
171109
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170829
[St] Status:MEDLINE


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[PMID]:28674586
[Au] Autor:Ngaroua; Eloundou NJ; Djibrilla Y; Asmaou O; Mbo AJ
[Ad] Endereço:Service de Chirurgie, Hôpital Régional de Ngaoundéré, Cameroun.
[Ti] Título:[Epidemiological, clinical aspects and management of urethral stenosis in adult patients in a District Hospital in Ngaoundéré, Cameroon].
[Ti] Título:Aspects épidémiologiques, cliniques et prise en charge de sténose urétrale chez l'adulte dans un Hôpital de District de Ngaoundéré, Cameroun..
[So] Source:Pan Afr Med J;26:193, 2017.
[Is] ISSN:1937-8688
[Cp] País de publicação:Uganda
[La] Idioma:fre
[Ab] Resumo:INTRODUCTION: The aim was to determine the epidemiological, clinical aspects and the management of these patients in Ngaoundere Protestant Hospital (HPN). METHODS: We conducted a retrospective review of complete medical records of patients hospitalized for urethral stenosis in the Department of Urology at the Protestant Hospital of Ngaoundéré over a one-year period (January 2013 to January 2014). RESULTS: Out of 69 registered medical records, a total of 57 patients files (all male) were identified for review. The average age was 52.6 (19 -85 years). The most represented age group was 41-60 years. Urethral stenosis accounted for 0.6% of consultations, 11.36 % of surgical hospitalizations and 6.96% of surgical procedures. Dysuria (70, 17%) was the main reason for consultation. Etiologies included infections (52,63%), traumas (26.32%) and iatrogenic problems (21.05%). All patients underwent CBEU which allowed to isolate gonococci (14,03%) and Escherichia coli (21.05%), the remainder of the urine culture was sterile (64.91%). 28 patients (49.12%) underwent retrograde uretrocystography (RUC), of whom 26 with anterior stenosis (92,85%). Internal endoscopic urethrotomy (IEU) was the most common surgical procedure (58%). Stenosis mainly occurred at the level of the bulbar and peno-bulbar regions. The rate of healing was 87,73% vs 12.27% of recurrences. CONCLUSION: Urethral stenosis is frequent in the Protestant Hospital of Ngaoundéré; patients requiring medical consultations are often in complex medical conditions. Internal endoscopic urethrotomy has shown plausible results.
[Mh] Termos MeSH primário: Disuria/epidemiologia
Endoscopia/métodos
Estreitamento Uretral/epidemiologia
[Mh] Termos MeSH secundário: Adulto
Idoso
Idoso de 80 Anos ou mais
Camarões/epidemiologia
Cistografia/métodos
Disuria/etiologia
Hospitais de Distrito
Seres Humanos
Masculino
Meia-Idade
Recidiva
Estudos Retrospectivos
Estreitamento Uretral/etiologia
Estreitamento Uretral/cirurgia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170717
[Lr] Data última revisão:
170717
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170705
[St] Status:MEDLINE
[do] DOI:10.11604/pamj.2017.26.193.9669


  9 / 4181 MEDLINE  
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[PMID]:28631919
[Au] Autor:Pryanichnikova MB; Zhurkina OV
[Ad] Endereço:Department of Urology Samara State Medical University, Samara, Russia.
[Ti] Título:[Rehabilitation of patients with complicated forms of urethral obliterations].
[So] Source:Urologiia;(2):122-125, 2017 Jun.
[Is] ISSN:1728-2985
[Cp] País de publicação:Russia (Federation)
[La] Idioma:rus
[Ab] Resumo:The article describes open surgical modalities for managing patients with severe obliterations of the anterior urethra. The mean age of patients was 70 years. The causes of urethral strictures and obliteration included prostatic adenomectomy, scrotal abscess with pelvic bone osteomyelitis, accidental removal of the bulbar and penile urethra during herniotomy and a prolonged use of an indwelling urethral catheter. Two patients underwent perineostomy (median and trapezoidal). In the third patient, scrotal skin was used to form "scrotal hypospadias" (a modified Johansons operation) and the fourth patient underwent Mikhalovskiis operation. All patients regained normal voiding.
[Mh] Termos MeSH primário: Estreitamento Uretral/reabilitação
[Mh] Termos MeSH secundário: Adenoma/cirurgia
Seres Humanos
Masculino
Meia-Idade
Neoplasias da Próstata/cirurgia
Escroto/cirurgia
Estreitamento Uretral/etiologia
Estreitamento Uretral/cirurgia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171103
[Lr] Data última revisão:
171103
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170621
[St] Status:MEDLINE


  10 / 4181 MEDLINE  
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[PMID]:28537690
[Au] Autor:Kurt O; Gevher F; Yazici CM; Erboga M; Dogru M; Aktas C
[Ad] Endereço:Department of Urology, Namik Kemal University, School of Medicine, Tekirdag, Turkey.
[Ti] Título:Effect of Mitomycin - C and Triamcinolone on Preventing Urethral Strictures.
[So] Source:Int Braz J Urol;43(5):939-945, 2017 Sep-Oct.
[Is] ISSN:1677-6119
[Cp] País de publicação:Brazil
[La] Idioma:eng
[Ab] Resumo:Urethral stricture is a common disease with high recurrence rate. Several manipulations were defined to prevent the recurrence but the results were disappointing. This study aimed to evaluate the efficacy of triamcinolone and mitomycin-C on urethral stricture formation and their effect on inhibition of urethral fibrosis. A total of 24 New Zealand rabbits were divided into 3 groups. Urethras of rabbits were traumatized with pediatric resectoscope. Resection area was irrigated with 10mL saline, swapped with a cotton wool soaked with 0.5mg/mL MMC and injected by 40mg triamcinolone in groups 1, 2 and 3 respectively. Retrograde urethrogram was performed at 28th day of procedure and the urethra was removed for histopathologic evaluation. There were significant differences in urethral diameters and in lumen reduction rate between the control and study groups (p<0.001). Compared to control group, all treatment groups showed mild fibrosis, less collagen bundle irregularity, and lower numbers of fibroblasts (p=0.003). The Tunnel assay showed that the number of apoptotic cells in the submucosal connective tissue was quantitatively higher in control groups (p=0.034). In the view of efficacy and safety, MMC and triamcinolone have the potential to replace the use of stents, clean intermittent catheterization, or long term catheters following internal urethrotomy. There were no statistically significant differences between two agents in terms of preventing urethral stricture formation in the present study. Mitomycin C and triamcinolone decreased the recurrence rates of urethral stricture.
[Mh] Termos MeSH primário: Mitomicina/uso terapêutico
Triancinolona/uso terapêutico
Estreitamento Uretral/prevenção & controle
[Mh] Termos MeSH secundário: Animais
Modelos Animais de Doenças
Masculino
Coelhos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
1ZK20VI6TY (Triamcinolone); 50SG953SK6 (Mitomycin)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171117
[Lr] Data última revisão:
171117
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170525
[St] Status:MEDLINE
[do] DOI:10.1590/S1677-5538.IBJU.2016.0191



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