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[PMID]:28582460
[Au] Autor:Giri A; Hartmann KE; Aldrich MC; Ward RM; Wu JM; Park AJ; Graff M; Qi L; Nassir R; Wallace RB; O'Sullivan MJ; North KE; Velez Edwards DR; Edwards TL
[Ad] Endereço:Vanderbilt Epidemiology Center, Institute for Medicine and Public Health, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America.
[Ti] Título:Admixture mapping of pelvic organ prolapse in African Americans from the Women's Health Initiative Hormone Therapy trial.
[So] Source:PLoS One;12(6):e0178839, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Evidence suggests European American (EA) women have two- to five-fold increased odds of having pelvic organ prolapse (POP) when compared with African American (AA) women. However, the role of genetic ancestry in relation to POP risk is not clear. Here we evaluate the association between genetic ancestry and POP in AA women from the Women's Health Initiative Hormone Therapy trial. Women with grade 1 or higher classification, and grade 2 or higher classification for uterine prolapse, cystocele or rectocele at baseline or during follow-up were considered to have any POP (N = 805) and moderate/severe POP (N = 156), respectively. Women with at least two pelvic exams with no indication for POP served as controls (N = 344). We performed case-only, and case-control admixture-mapping analyses using multiple logistic regression while adjusting for age, BMI, parity and global ancestry. We evaluated the association between global ancestry and POP using multiple logistic regression. European ancestry at the individual level was not associated with POP risk. Case-only and case-control local ancestry analyses identified two ancestry-specific loci that may be associated with POP. One locus (Chromosome 15q26.2) achieved empirically-estimated statistical significance and was associated with decreased POP odds (considering grade ≥2 POP) with each unit increase in European ancestry (OR: 0.35; 95% CI: 0.30, 0.57; p-value = 1.48x10-5). This region includes RGMA, a potent regulator of the BMP family of genes. The second locus (Chromosome 1q42.1-q42.3) was associated with increased POP odds with each unit increase in European ancestry (Odds ratio [OR]: 1.69; 95% confidence interval [CI]: 1.28, 2.22; p-value = 1.93x10-4). Although this region did not reach statistical significance after considering multiple comparisons, it includes potentially relevant genes including TBCE, and ACTA1. Unique non-overlapping European and African ancestry-specific susceptibility loci may be associated with increased POP risk.
[Mh] Termos MeSH primário: Cistocele/genética
Locos de Características Quantitativas
Característica Quantitativa Herdável
Retocele/genética
Prolapso Uterino/genética
[Mh] Termos MeSH secundário: Actinas/genética
Afroamericanos
Idoso
Índice de Massa Corporal
Estudos de Casos e Controles
Cistocele/diagnóstico
Cistocele/patologia
Grupo com Ancestrais do Continente Europeu
Feminino
Proteínas Ligadas por GPI/genética
Expressão Gênica
Seres Humanos
Modelos Logísticos
Meia-Idade
Chaperonas Moleculares/genética
Proteínas do Tecido Nervoso/genética
Razão de Chances
Paridade
Retocele/diagnóstico
Retocele/patologia
Fatores de Risco
Índice de Gravidade de Doença
Estados Unidos
Prolapso Uterino/diagnóstico
Prolapso Uterino/patologia
Saúde da Mulher
[Pt] Tipo de publicação:CLINICAL TRIAL; JOURNAL ARTICLE; MULTICENTER STUDY
[Nm] Nome de substância:
0 (Actins); 0 (GPI-Linked Proteins); 0 (Molecular Chaperones); 0 (Nerve Tissue Proteins); 0 (RGMA protein, human); 0 (TBCE protein, human)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170919
[Lr] Data última revisão:
170919
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170606
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0178839


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[PMID]:28364872
[Au] Autor:Cagnacci A; Palma F; Napolitano A; Xholli A
[Ad] Endereço:Department of Obstetrics, Gynaecology and Paediatrics, Azienda Policlinico of Modena, Modena, Italy. Electronic address: angelo.cagnacci@uniud.it.
[Ti] Título:Association between pelvic organ prolapse and climacteric symptoms in postmenopausal women.
[So] Source:Maturitas;99:73-78, 2017 May.
[Is] ISSN:1873-4111
[Cp] País de publicação:Ireland
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To evaluate whether climacteric symptoms are related to pelvic organ prolapse (POP) in postmenopausal women. STUDY DESIGN: A cross-sectional investigation was performed on 1382 postmenopausal women attending an outpatient service for menopause at a university hospital. MAIN OUTCOME MEASURES: Data regarding climacteric symptoms, as captured by the Greene Climacteric Scale, and objective POP were retrieved from an electronic database. Additional data retrieved were age, anthropometric measures, personal and reproductive history, use of medication or drugs, coffee, smoking, state of anxiety (STAI scale score) and depression (Zung scale score). RESULTS: The score of Greene Climacteric Scale was higher (p=0.02) in women with (n=538) than in those without (n=844) POP (29.6±13.6 vs. 27.8±13.; p=0.02). In multiple logistic regression models, the score was independently related to POP as a whole (OR 1.012; 95%CI 1.003,1.022; p=0.009), and to bladder prolapse (OR 1.011; 95%CI 1.007,1.07; p=0.02) or to uterus prolapse (OR 1.003; 95%CI 0.99,1.016; p=0.63) or rectum prolapse (rectocele) (OR 1.004; 95%CI 0.988,1.02; p=0.62). CONCLUSIONS: In postmenopausal women, a higher burden of climacteric symptoms, is associated with POP. Underlying mechanisms were not assessed and deserve further investigation.
[Mh] Termos MeSH primário: Ansiedade/epidemiologia
Depressão/epidemiologia
Fogachos/epidemiologia
Menopausa
Prolapso de Órgão Pélvico/epidemiologia
Saúde Reprodutiva
[Mh] Termos MeSH secundário: Ansiedade/psicologia
Café
Estudos Transversais
Cistocele/epidemiologia
Depressão/psicologia
Escolaridade
Feminino
Fogachos/psicologia
Seres Humanos
Histerectomia
Modelos Logísticos
Meia-Idade
Análise Multivariada
Pós-Menopausa
Retocele/epidemiologia
Fatores de Risco
Fumar/epidemiologia
Prolapso Uterino/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Coffee)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170602
[Lr] Data última revisão:
170602
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170403
[St] Status:MEDLINE


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[PMID]:28238313
[Au] Autor:Dubuisson JB; Veit-Rubin N; Wenger JM; Dubuisson J
[Ad] Endereço:Clinique La Colline, université de Genève, 1206 Genève, Suisse. Electronic address: dubuissonjeanbernard@hotmail.com.
[Ti] Título:[Laparoscopic lateral suspension, another way to treat genital prolapse].
[Ti] Título:La suspension latérale cÅ“lioscopique, une autre façon de traiter les prolapsus génitaux..
[So] Source:Gynecol Obstet Fertil Senol;45(1):32-36, 2017 Jan.
[Is] ISSN:2468-7189
[Cp] País de publicação:France
[La] Idioma:fre
[Ab] Resumo:The laparoscopic sacrocolpopexy is the treatment of choice of pelvic organ prolapses since more than twenty years. The laparoscopic lateral suspension with mesh is an alternative technique. Its originality is the subperitoneal passing of the lateral arm of the mesh in the lateral abdominal wall, leaving the skin above the iliac crest, in a place without risks of vascular, nerve, bowel injuries. We report in this article the results of the three main publications on the subject. The indications are cystocele and apical descent. It can be envisaged when the access of the promontory is difficult; for instance in the presence of obesity, adhesions, sigmoid megacolon, or low position of the left common iliac vein, partially covering the promontory. It is also a practical technique for surgeons having a moderate experience of the promontory access.
[Mh] Termos MeSH primário: Procedimentos Cirúrgicos em Ginecologia/métodos
Laparoscopia/métodos
Prolapso de Órgão Pélvico/cirurgia
[Mh] Termos MeSH secundário: Idoso
Contraindicações
Cistocele/cirurgia
Feminino
Seres Humanos
Meia-Idade
Telas Cirúrgicas
Vagina/cirurgia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170228
[St] Status:MEDLINE


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[PMID]:28192248
[Au] Autor:Barski D; Arndt C; Gerullis H; Yang J; Boros M; Otto T; Kolberg HC
[Ad] Endereço:Department of Urology, Lukas Hospital, Neuss, Germany. Electronic address: dbarski@lukasneuss.de.
[Ti] Título:Transvaginal PVDF-mesh for cystocele repair: A cohort study.
[So] Source:Int J Surg;39:249-254, 2017 Mar.
[Is] ISSN:1743-9159
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: Optimized biocompatibility of new materials is a major requirement for transvaginal meshes for pelvic organ prolapse (POP) repair. Polyvinylidene fluoride (PVDF) presented good characteristics in prior animal experiments and clinical use in humans. METHODS: Between 01/2012 and 04/2016 37 women underwent transvaginal repair of symptomatic prolapse of the anterior vaginal wall (cystocele) with PVDF-mesh in a single institution. A chart review for recurrence, continence, peri- and early postoperative complications was performed. Referring practitioners were interviewed by telephone and mail. Additionally patient reported outcome and satisfaction were measured by Patient Global Improvement Inventory (PGI-I) scale. RESULTS: 34 women were eligible for a mean follow up of 19 months. The functional outcome improved significantly. One symptomatic vault prolapse (2.9%) and two reoperations for incontinence (5.9%) occurred. Two mesh exposures (5.9%) occurred and were treated conservatively. No other severe complications were registered. 87.5% of treated women felt very much better or much better and would undergo the surgery again. A cohort study including development steps in accordance with the IDEAL system is presented. CONCLUSIONS: For the first time we report on effectivity and safety of transvaginal application of PVDF-mesh in real-life practice. A prospective long-term evaluation in a registry is justified.
[Mh] Termos MeSH primário: Cistocele/cirurgia
Telas Cirúrgicas
[Mh] Termos MeSH secundário: Adulto
Idoso
Materiais Biocompatíveis
Estudos de Coortes
Colpotomia/instrumentação
Colpotomia/métodos
Feminino
Seres Humanos
Meia-Idade
Satisfação do Paciente
Polivinil
Complicações Pós-Operatórias
Próteses e Implantes
Reoperação
Estudos Retrospectivos
Resultado do Tratamento
Incontinência Urinária/cirurgia
Vagina/cirurgia
[Pt] Tipo de publicação:EVALUATION STUDIES; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Biocompatible Materials); 0 (Polyvinyls); 24937-79-9 (polyvinylidene fluoride)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170509
[Lr] Data última revisão:
170509
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170214
[St] Status:MEDLINE


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[PMID]:28155202
[Au] Autor:Houman J; Weinberger JM; Eilber KS
[Ad] Endereço:Urology Resident, Cedars-Sinai Health System, 8631 West 3rd Street, Suite 930E, Los Angeles, CA, 90048, USA.
[Ti] Título:Native Tissue Repairs for Pelvic Organ Prolapse.
[So] Source:Curr Urol Rep;18(1):6, 2017 Jan.
[Is] ISSN:1534-6285
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Pelvic organ prolapse (POP) is a generalized term that refers to prolapse of any of the three vaginal compartments: anterior (cystocele), posterior (rectocele), and apical (uterine and vault prolapse). POP may affect up to 50% of parous women, and as a result, one in nine women will undergo at least one surgery for POP in her lifetime. Native tissue repair is the cornerstone of prolapse surgery, especially in light of the scrutiny placed on the use of mesh for prolapse. Refinements in the procedures over time have been based on both basic anatomy and fundamentals of surgery, as well as the ongoing acquisition of new knowledge through clinical studies.
[Mh] Termos MeSH primário: Prolapso de Órgão Pélvico/cirurgia
[Mh] Termos MeSH secundário: Cistocele/cirurgia
Feminino
Procedimentos Cirúrgicos em Ginecologia/métodos
Seres Humanos
Retocele/cirurgia
Resultado do Tratamento
Vagina/cirurgia
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1702
[Cu] Atualização por classe:171107
[Lr] Data última revisão:
171107
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170204
[St] Status:MEDLINE
[do] DOI:10.1007/s11934-017-0648-0


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[PMID]:28108984
[Au] Autor:Huang WC; Yang JM
[Ad] Endereço:Department of Obstetrics and Gynecology, Cathay General Hospital, Taipei, Taiwan.
[Ti] Título:A Proximal Straining Mesh Location Is Associated With De Novo Stress Urinary Incontinence After Transobturator Mesh Procedures.
[So] Source:J Ultrasound Med;36(3):539-545, 2017 Mar.
[Is] ISSN:1550-9613
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: The purpose of this study was to explore the association between mesh location and de novo stress urinary incontinence (SUI) after transvaginal mesh procedures. METHODS: We retrospectively analyzed a database of women who had received transvaginal mesh procedures for stage III or greater cystocele according to the Pelvic Organ Prolapse Quantification system. Only data for women who neither reported SUI preoperatively nor had received concomitant anti-incontinence surgery were included for analyses. The mesh location was investigated by sonography via the percentage of the urethra covered by mesh, defined as the number calculated by dividing the portion of the urethral length covered by mesh (the distance from the bladder neck to the point of the urethra, which was indicated by an imaginary line at the level of the lower [caudal] mesh end and perpendicular to the urethra) by the total urethral length (the distance from the bladder neck to the external urethral meatus) in the sagittal plane. The resting, straining, coughing, and squeezing mesh locations of women who did (n = 29) and did not (n = 54) report SUI at the 12-month follow-up were compared. RESULTS: At the 12-month follow-up, women who reported SUI had a significantly smaller straining percentage of the urethra covered by mesh (mean ± SD, 28.5% ± 9.6%) compared with continent women (35.2% ± 15.8%), indicating a more proximal straining mesh location. CONCLUSIONS: Sonography is useful in investigating the location of the transvaginal mesh. De novo SUI after transvaginal mesh procedures is associated with a more proximal straining mesh location.
[Mh] Termos MeSH primário: Cistocele/cirurgia
Complicações Pós-Operatórias/diagnóstico por imagem
Slings Suburetrais
Telas Cirúrgicas
Ultrassonografia
Incontinência Urinária por Estresse/diagnóstico por imagem
[Mh] Termos MeSH secundário: Idoso
Feminino
Seguimentos
Seres Humanos
Estudos Retrospectivos
Uretra/diagnóstico por imagem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171004
[Lr] Data última revisão:
171004
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170122
[St] Status:MEDLINE
[do] DOI:10.7863/ultra.16.03044


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[PMID]:27928684
[Au] Autor:Pasquer A; Djeudji F; Pechoux A; Barth X
[Ad] Endereço:Department of Digestive and Colorectal Surgery, Edouard Herriot University Hospital, 5 Place d'Arsonval, 69003, Lyon, France. arnaud.pasquer@chu-lyon.fr.
[Ti] Título:Spondylodiscitis after rectopexy: diagnostic of a rare complication.
[So] Source:Tech Coloproctol;21(1):63-64, 2017 Jan.
[Is] ISSN:1128-045X
[Cp] País de publicação:Italy
[La] Idioma:eng
[Mh] Termos MeSH primário: Abscesso Abdominal/complicações
Discite/etiologia
Vértebras Lombares
Complicações Pós-Operatórias/etiologia
Sacro
[Mh] Termos MeSH secundário: Idoso
Cistocele/cirurgia
Feminino
Seres Humanos
Prolapso Retal/cirurgia
[Pt] Tipo de publicação:CASE REPORTS; LETTER
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161209
[St] Status:MEDLINE
[do] DOI:10.1007/s10151-016-1566-8


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[PMID]:27894034
[Au] Autor:Rahkola-Soisalo P; Altman D; Falconer C; Morcos E; Rudnicki M; Mikkola TS
[Ad] Endereço:University of Helsinki and Helsinki University Central Hospital, Department of Obstetrics and Gynecology, Finland. Electronic address: paivi.rahkola-soisalo@hus.fi.
[Ti] Título:Quality of life after Uphold™ Vaginal Support System surgery for apical pelvic organ prolapse-A prospective multicenter study.
[So] Source:Eur J Obstet Gynecol Reprod Biol;208:86-90, 2017 Jan.
[Is] ISSN:1872-7654
[Cp] País de publicação:Ireland
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To study the effects on quality of life in women operated for apical pelvic organ prolapse using the Vaginal Uphold™ System. STUDY DESIGN: In this prospective cohort study, women (n=207) with symptomatic apical prolapse, with or without cystocele, were operated using the Uphold™ Vaginal Support System. Follow-up for quality of life was performed at 12 months after surgery, and assessed by the PFDI-20, and PFIQ-7, and sexual function by the PISQ-12. We used odds ratios (ORs) with 95% confidence intervals (CIs) for outcome association analyses using logistic regression. RESULTS: At one-year follow-up majority of women experienced an overall postoperative improvement in quality of life (p<0.001). One year after surgery Uphold™ operation alone increased the risk for prolapse related bother as compared to Uphold™ combined with anterior colporraphy (POP-IQ-7; OR 2.1; 95% CI 1.01-4.3). The frequency of dyspareunia decreased postoperatively (p=0.004), however, after one-year, overall sexual function deteriorated significantly (p<0.001). The worsening in sexual function scores was mainly attributed to the partner related domain, whereas the behavioral-emotive and physical domains showed no significant changes. CONCLUSION: Apical prolapse repair using Uphold™ improved quality of life among our patients but worsened overall sexual function postoperatively.
[Mh] Termos MeSH primário: Diafragma da Pelve/cirurgia
Prolapso de Órgão Pélvico/cirurgia
Complicações Pós-Operatórias/etiologia
Qualidade de Vida
Disfunções Sexuais Fisiológicas/etiologia
Telas Cirúrgicas/efeitos adversos
[Mh] Termos MeSH secundário: Adulto
Idoso
Idoso de 80 Anos ou mais
Estudos de Coortes
Cistocele/complicações
Cistocele/cirurgia
Feminino
Seguimentos
Seres Humanos
Meia-Idade
Duração da Cirurgia
Satisfação do Paciente
Prolapso de Órgão Pélvico/complicações
Complicações Pós-Operatórias/epidemiologia
Complicações Pós-Operatórias/fisiopatologia
Complicações Pós-Operatórias/prevenção & controle
Estudos Prospectivos
Fatores de Risco
Países Escandinavos e Nórdicos/epidemiologia
Autorrelato
Índice de Gravidade de Doença
Disfunções Sexuais Fisiológicas/epidemiologia
Disfunções Sexuais Fisiológicas/fisiopatologia
Disfunções Sexuais Fisiológicas/prevenção & controle
[Pt] Tipo de publicação:JOURNAL ARTICLE; MULTICENTER STUDY
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170419
[Lr] Data última revisão:
170419
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161129
[St] Status:MEDLINE


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[PMID]:27615439
[Au] Autor:Swenson CW; Smith TM; Luo J; Kolenic GE; Ashton-Miller JA; DeLancey JO
[Ad] Endereço:Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI. Electronic address: scarolyn@med.umich.edu.
[Ti] Título:Intraoperative cervix location and apical support stiffness in women with and without pelvic organ prolapse.
[So] Source:Am J Obstet Gynecol;216(2):155.e1-155.e8, 2017 Feb.
[Is] ISSN:1097-6868
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: It is unknown how initial cervix location and cervical support resistance to traction, which we term "apical support stiffness," compare in women with different patterns of pelvic organ support. Defining a normal range of apical support stiffness is important to better understand the pathophysiology of apical support loss. OBJECTIVE: The aims of our study were to determine whether: (1) women with normal apical support on clinic Pelvic Organ Prolapse Quantification, but with vaginal wall prolapse (cystocele and/or rectocele), have the same intraoperative cervix location and apical support stiffness as women with normal pelvic support; and (2) all women with apical prolapse have abnormal intraoperative cervix location and apical support stiffness. A third objective was to identify clinical and biomechanical factors independently associated with clinic Pelvic Organ Prolapse Quantification point C. STUDY DESIGN: We conducted an observational study of women with a full spectrum of pelvic organ support scheduled to undergo gynecologic surgery. All women underwent a preoperative clinic examination, including Pelvic Organ Prolapse Quantification. Cervix starting location and the resistance (stiffness) of its supports to being moved steadily in the direction of a traction force that increased from 0-18 N was measured intraoperatively using a computer-controlled servoactuator device. Women were divided into 3 groups for analysis according to their pelvic support as classified using the clinic Pelvic Organ Prolapse Quantification: (1) "normal/normal" was women with normal apical (C < -5 cm) and vaginal (Ba and Bp < 0 cm) support; (2) normal/prolapse had normal apical support (C < -5 cm) but prolapse of the anterior or posterior vaginal walls (Ba and/or Bp ≥ 0 cm); and (3) prolapse/prolapse had both apical and vaginal wall prolapse (C > -5 cm and Ba and/or Bp ≥ 0 cm). Demographics, intraoperative cervix locations, and apical support stiffness values were then compared. Normal range of cervix location during clinic examination and operative testing was defined by the total range of values observed in the normal/normal group. The proportion of women in each group with cervix locations within and outside the normal range was determined. Linear regression was performed to identify variables independently associated with clinic Pelvic Organ Prolapse Quantification point C. RESULTS: In all, 52 women were included: 14 in the normal/normal group, 11 in the normal/prolapse group, and 27 in the prolapse/prolapse group. At 1 N of traction force in the operating room, 50% of women in the normal/prolapse group had cervix locations outside the normal range while 10% had apical support stiffness outside the normal range. Of women in the prolapse/prolapse group, 81% had cervix locations outside the normal range and 8% had apical support stiffness outside the normal range. Similar results for cervix locations were observed at 18 N of traction force; however the proportion of women with apical support stiffness outside the normal range increased to 50% in the normal/prolapse group and 59% in the prolapse/prolapse group. The prolapse/prolapse group had statistically lower apical support stiffness compared to the normal/normal group with increased traction from 1-18 N (0.47 ± 0.18 N/mm vs 0.63 ± 0.20 N/mm, P = .006), but all other comparisons were nonsignificant. After controlling for age, parity, body mass index, and apical support stiffness, cervix location at 1 N traction force remained an independent predictor of clinic Pelvic Organ Prolapse Quantification point C, but only in the prolapse/prolapse group. CONCLUSION: Approximately 50% of women with cystocele and/or rectocele but normal apical support in the clinic had cervix locations outside the normal range under intraoperative traction, while 19% of women with uterine prolapse had normal apical support. Identifying women whose apical support falls outside a defined normal range may be a more accurate way to identify those who truly need a hysterectomy and/or an apical support procedure and to spare those who do not.
[Mh] Termos MeSH primário: Colo do Útero/fisiopatologia
Cistocele/fisiopatologia
Retocele/fisiopatologia
Prolapso Uterino/fisiopatologia
[Mh] Termos MeSH secundário: Adulto
Idoso
Estudos de Casos e Controles
Colo do Útero/patologia
Feminino
Seres Humanos
Período Intraoperatório
Meia-Idade
Prolapso de Órgão Pélvico/fisiopatologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; OBSERVATIONAL STUDY
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170531
[Lr] Data última revisão:
170531
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:160913
[St] Status:MEDLINE


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[PMID]:27614758
[Au] Autor:Nishimura K; Yoshimura K; Hoshino K; Hachisuga T
[Ad] Endereço:Department of Obstetrics and Gynecology, Wakamatsu Hospital of the University of Occupational and Environmental Health, 1-17-1 Hamamachi, Wakamatsu-ku, Kitakyushu, 808-0024, Japan.
[Ti] Título:Laparoscopic fixation of the vaginal cuff to the uterosacral ligaments at the time of hysterectomy.
[So] Source:Int Urogynecol J;28(2):321-323, 2017 Feb.
[Is] ISSN:1433-3023
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION AND HYPOTHESIS: Transvaginal ipsilateral uterosacral ligament colpopexy for pelvic organ prolapse (POP), which was reported by Shull et al. (Shull's colpopexy) in 2000, is one of the most frequently performed non-mesh pelvic floor reconstructive surgical procedures. Despite its excellent anatomical outcomes, ureteral injury and difficulty in uterosacral ligament detection (especially in patients with severe POP) are typical issues with this procedure. METHOD: This video demonstrates the procedure in a 58-year-old woman, gravida 2 para 2, with POP-Q stage II uterine prolapse and stage I cystocele. At the beginning of the operation, the bilateral uterosacral ligaments were confirmed and separated from the ureters after entering the retroperitoneal space. The inferior hypogastric nerve and pelvic nerve plexus were also separated from the uterosacral ligament. After total laparoscopic hysterectomy, three ipsilateral delayed absorbable monofilament sutures were placed between the uterosacral ligament and the vaginal cuff. Retroperitonealization was then performed using a continuous suture with closure of the Douglas pouch. CONCLUSION: Laparoscopic Shull's colpopexy for POP is a secure procedure with the advantages of laparoscopy (magnification and sharing the operative field). This may become one of the most useful operations for apical support as native tissue repair.
[Mh] Termos MeSH primário: Cistocele/cirurgia
Histerectomia Vaginal/métodos
Prolapso de Órgão Pélvico/cirurgia
[Mh] Termos MeSH secundário: Seres Humanos
Histerectomia Vaginal/efeitos adversos
Laparoscopia
Ligamentos/cirurgia
Meia-Idade
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; VIDEO-AUDIO MEDIA
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170920
[Lr] Data última revisão:
170920
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160912
[St] Status:MEDLINE
[do] DOI:10.1007/s00192-016-3137-y



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