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[PMID]:29424516
[Au] Autor:Hernández-Escobar CE; Carrillo-Martínez MA; Arroyo-Lemarroy T; ZamoraMorales MT; Garza-García GA; Campos-Sanmiguel E
[Ti] Título:[Uterine arteriovenous malformation as cause of uterine bleeding of sudden onset. Doppler ultrasound utility, other imaging methods and the minimally invasive treatment].
[Ti] Título:Malformación arteriovenosa uterina como causa de hemorragia uterina súbita. Utilidad del ultrasonido Doppler de consultorio, otros métodos de imagen y tratamiento de mínima invasion..
[So] Source:Ginecol Obstet Mex;84(8):535-41, 2016 08.
[Is] ISSN:0300-9041
[Cp] País de publicação:Mexico
[La] Idioma:spa
[Ab] Resumo:Background: Uterine arteriovenous malformation is a rare disorder that can cause sudden life-threatening vaginal bleeding. Objetive: To present the clinical features in addition to the use of office gynecologic ultrasound and other imaging techniques in the diagnosis and minimally-invasive treatment of a patient with sudden vaginal bleeding resulting from a uterine arteriovenous malformation. Case report: A 31 year old woman presented sudden onset vaginal bleeding requiring the transfusion of 3 units of red blood cells. An initial diagnosis of uterine arteriovenous malformation was made using an office gynecological ultrasound and Color Doppler sonography. The patient was referred to interventional radiology for confirmation of the diagnosis and patient care. The diagnosis and localization of the uterine arteriovenous malformation was confirmed using magnetic resonance imaging. Therapeutic management proceeded with superselective angiography and embolization of the supplying arteries resulting in immediate symptomatic resolution. Conclusion: The use of office gynecologic ultrasound in combination with other imaging techniques is an important tool in the diagnosis and localization of uterine arteriovenous malformation. Embolization of supplying arteries is considered a safe and effective therapeutic option due to advances in radiologic intervention techniques. Advantages of this procedure include a minimally-invasive technique, low morbidity and preservation of uterine function.
[Mh] Termos MeSH primário: Malformações Arteriovenosas/complicações
Embolização da Artéria Uterina/métodos
Hemorragia Uterina/etiologia
Útero/irrigação sanguínea
[Mh] Termos MeSH secundário: Adulto
Malformações Arteriovenosas/diagnóstico por imagem
Malformações Arteriovenosas/terapia
Feminino
Seres Humanos
Imagem por Ressonância Magnética
Ultrassonografia Doppler em Cores
Hemorragia Uterina/terapia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180301
[Lr] Data última revisão:
180301
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180210
[St] Status:MEDLINE


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[PMID]:29417683
[Au] Autor:Neto MC
[Ad] Endereço:University of São Paulo, Department of Obstetrics and Gynecology, Medical School of Ribeirão Preto, av. Bandeirantes 3900, Monte Alegre, Ribeirão Preto, São Paulo, 14049-900, Brazil.
[Ti] Título:Re: International Endometrial Tumor Analysis (IETA) terminology in women with postmenopausal bleeding and sonographic endometrial thickness ≥ 4.5 mm: agreement and reliability study. P. Sladkevicius, A. Installé, T. Van den Bosch, D. Timmerman, B. Benacerraf, L. Jokubkiene, A. Di Legge, A. Votino, L. Zannoni, B. De Moor, B. De Cock, B. Van Calster and L. Valentin. Ultrasound Obstet Gynecol 2018; 51: 259-268.
[So] Source:Ultrasound Obstet Gynecol;51(2):167-168, 2018 02.
[Is] ISSN:1469-0705
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Pós-Menopausa
Hemorragia Uterina
[Mh] Termos MeSH secundário: Neoplasias do Endométrio
Endométrio
Feminino
Seres Humanos
Reprodutibilidade dos Testes
Ultrassonografia
[Pt] Tipo de publicação:JOURNAL ARTICLE; COMMENT
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180228
[Lr] Data última revisão:
180228
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180209
[St] Status:MEDLINE
[do] DOI:10.1002/uog.18998


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[PMID]:29390473
[Au] Autor:Zhao H; Yao Y; Yang H; Ma D; Chen A
[Ad] Endereço:Department of Gynecology, The Affiliated Hospital of Qingdao University, Qingdao, PR China.
[Ti] Título:Hormone therapy as a management strategy for lung metastasis after 5 years of endometrial cancer: A case report and literature review.
[So] Source:Medicine (Baltimore);96(51):e9223, 2017 Dec.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:RATIONALE: Endometrial cancer patients with lung metastases are rare, and more rarely with long-term management of progesterone after recurrence. PATIENT CONCERNS: Informed consent of the patients and their families. DIAGNOSES: Endometrial cancer (IVB) (Refer to 2009 FIGO stag of endometrial cancer). INTERVENTIONS: the patient was treated with Megestrol Acetate Dispersible Tablets (trade name Yilizhi), 160 mg, orally, once daily, without interruption. OUTCOMES: The patient has been treated with progesterone therapy for stable conditions and her survival time is already roughly a decade (December 2006-October 2016). LESSONS: Hormone therapy may as a long-term management for hormone receptor-positive patients with recurrent endometrial cancer.
[Mh] Termos MeSH primário: Adenocarcinoma/cirurgia
Neoplasias do Endométrio/cirurgia
Neoplasias Pulmonares/tratamento farmacológico
Neoplasias Pulmonares/secundário
Megestrol/uso terapêutico
[Mh] Termos MeSH secundário: Adenocarcinoma/secundário
Administração Oral
Antineoplásicos Hormonais/uso terapêutico
Biópsia por Agulha
Neoplasias do Endométrio/diagnóstico
Feminino
Seguimentos
Seres Humanos
Histerectomia/métodos
Imuno-Histoquímica
Neoplasias Pulmonares/diagnóstico por imagem
Meia-Idade
Invasividade Neoplásica/patologia
Recidiva Local de Neoplasia/tratamento farmacológico
Recidiva Local de Neoplasia/patologia
Estadiamento de Neoplasias
Medição de Risco
Fatores de Tempo
Tomografia Computadorizada por Raios X/métodos
Resultado do Tratamento
Hemorragia Uterina/diagnóstico
Hemorragia Uterina/etiologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Antineoplastic Agents, Hormonal); EA6LD1M70M (Megestrol)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180214
[Lr] Data última revisão:
180214
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180203
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000009223


  4 / 7892 MEDLINE  
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[PMID]:29341573
[Au] Autor:Spremovic-Radenovic S; Stefanovic A; Kadija S; Jeremic K; Sparic R
[Ti] Título:Classification and the diagnostics of abnormal uterine bleeding in nongravid women of reproductive age: The PALM-COEIN classification system adopted by the International Federation of Gynecology and Obstetrics.
[So] Source:Vojnosanit Pregl;73(12):1154-9, 2016 Dec.
[Is] ISSN:0042-8450
[Cp] País de publicação:Serbia
[La] Idioma:eng
[Mh] Termos MeSH primário: Reprodução
Terminologia como Assunto
Hemorragia Uterina/diagnóstico
[Mh] Termos MeSH secundário: Fatores Etários
Feminino
Seres Humanos
Guias de Prática Clínica como Assunto
Valor Preditivo dos Testes
Prognóstico
Fatores de Risco
Hemorragia Uterina/classificação
Hemorragia Uterina/etiologia
Hemorragia Uterina/terapia
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180213
[Lr] Data última revisão:
180213
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180118
[St] Status:MEDLINE
[do] DOI:10.2298/VSP160709289S


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[PMID]:29336430
[Au] Autor:Biswas R; Saxena P; Gupta U; Choudhary N; Chawla R
[Ad] Endereço:Department of Obstetrics and Gynaecology, Lady Hardinge Medical College, New Delhi, India.
[Ti] Título:Persistent Trophoblastic Disease at Cesarean Scar.
[So] Source:Kathmandu Univ Med J (KUMJ);14(56):376-379, 2016 Oct.-Dec..
[Is] ISSN:1812-2078
[Cp] País de publicação:Nepal
[La] Idioma:eng
[Ab] Resumo:Pregnancy over the cesarean scar is the rarest cause of ectopic pregnancy and development of persistent trophoblastic disease at the scar site is extremely rare. A high index of suspicion is needed for early diagnosis and management of cesarean scar molar pregnancy. This condition is difficult to diagnose and must be considered in the patient with a history of cesarean section who has persistent vaginal bleeding or symptoms of pregnancy after suction evacuation. Diagnosis can be confirmedby measuring ß Human Chorionic Gonadotropin levels, transvaginal ultrasound with doppler flow evaluation. As this is an uncommon condition, this case report with conservative non surgical approach will add up to its clinical spectrum.
[Mh] Termos MeSH primário: Cesárea/efeitos adversos
Cicatriz/patologia
Gravidez Ectópica/diagnóstico
Gravidez Ectópica/patologia
Trofoblastos/patologia
[Mh] Termos MeSH secundário: Adulto
Feminino
Seres Humanos
Gravidez
Ultrassonografia
Hemorragia Uterina/etiologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180129
[Lr] Data última revisão:
180129
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180117
[St] Status:MEDLINE


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[PMID]:28455086
[Au] Autor:Luke B; Gopal D; Cabral H; Stern JE; Diop H
[Ad] Endereço:Department of Obstetrics, Gynecology, and Reproductive Biology, College of Human Medicine, Michigan State University, East Lansing, MI. Electronic address: lukeb@msu.edu.
[Ti] Título:Adverse pregnancy, birth, and infant outcomes in twins: effects of maternal fertility status and infant gender combinations; the Massachusetts Outcomes Study of Assisted Reproductive Technology.
[So] Source:Am J Obstet Gynecol;217(3):330.e1-330.e15, 2017 09.
[Is] ISSN:1097-6868
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: It is unknown whether the risk of adverse outcomes in twin pregnancies among subfertile women, conceived with and without in vitro fertilization, differs from those conceived spontaneously. OBJECTIVE: We sought to evaluate the effects of fertility status on adverse perinatal outcomes in twin pregnancies on a population basis. STUDY DESIGN: All twin live births of ≥22 weeks' gestation and ≥350 g birthweight to Massachusetts resident women in 2004 through 2010 were linked to hospital discharge records, vital records, and in vitro fertilization cycles. Women were categorized by their fertility status as in vitro fertilization, subfertile, or fertile, and by twin pair genders (all, like, unlike). Women whose births linked to in vitro fertilization cycles were classified as in vitro fertilization; those with indicators of subfertility but without in vitro fertilization treatment were classified as subfertile; all others were classified as fertile. Risks of 6 adverse pregnancy outcomes (gestational diabetes, pregnancy hypertension, uterine bleeding, placental complications [placenta abruptio, placenta previa, and vasa previa], prenatal hospitalizations, and primary cesarean) and 9 adverse infant outcomes (very low birthweight, low birthweight, small-for-gestation birthweight, large-for-gestation birthweight, very preterm [<32 weeks], preterm, birth defects, neonatal death, and infant death) were modeled by fertility status with the fertile group as reference, using multivariate log binomial regression and reported as adjusted relative risk ratios and 95% confidence intervals. RESULTS: The study population included 10,352 women with twin pregnancies (6090 fertile, 724 subfertile, and 3538 in vitro fertilization). Among all twins, the risks for all 6 adverse pregnancy outcomes were significantly increased for the subfertile and in vitro fertilization groups, with highest risks for uterine bleeding (adjusted relative risk ratios, 1.92 and 2.58, respectively) and placental complications (adjusted relative risk ratios, 2.07 and 1.83, respectively). Among all twins, the risks for those born to subfertile women were significantly increased for very preterm birth and neonatal and infant death (adjusted relative risk ratios, 1.36, 1.89, and 1.87, respectively). Risks were significantly increased among in vitro fertilization twins for very preterm birth, preterm birth, and birth defects (adjusted relative risk ratios, 1.28, 1.07, and 1.26, respectively). CONCLUSION: Risks of all maternal and most infant adverse outcomes were increased for subfertile and in vitro fertilization twins. Among all twins, the highest risks were for uterine bleeding and placental complications for the subfertile and in vitro fertilization groups, and neonatal and infant death in the subfertile group. These findings provide further evidence supporting single embryo transfer and more cautious use of ovulation induction.
[Mh] Termos MeSH primário: Fertilização In Vitro
Infertilidade
Gravidez de Gêmeos
[Mh] Termos MeSH secundário: Adulto
Apresentação Pélvica/epidemiologia
Cesárea/estatística & dados numéricos
Anormalidades Congênitas/epidemiologia
Feminino
Seres Humanos
Recém-Nascido de Baixo Peso
Masculino
Massachusetts/epidemiologia
Doenças Placentárias/epidemiologia
Gravidez
Nascimento Prematuro/epidemiologia
Transferência de Embrião Único
Hemorragia Uterina/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL
[Em] Mês de entrada:1709
[Cu] Atualização por classe:180111
[Lr] Data última revisão:
180111
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170430
[St] Status:MEDLINE


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[PMID]:28471022
[Au] Autor:Jurkovic D
[Ad] Endereço:Institute for Women's Health, University College Hospital London, London, UK.
[Ti] Título:Re: Prospective temporal validation of mathematical models to calculate risk of endometrial malignancy in patients with postmenopausal bleeding. P. Sladkevicius, G. Opolskiene and L. Valentin. Ultrasound Obstet Gynecol 2017;49: 649-656.
[So] Source:Ultrasound Obstet Gynecol;49(5):565-566, 2017 05.
[Is] ISSN:1469-0705
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Pós-Menopausa
Hemorragia Uterina
[Mh] Termos MeSH secundário: Neoplasias do Endométrio
Feminino
Seres Humanos
Modelos Teóricos
Estudos Prospectivos
[Pt] Tipo de publicação:JOURNAL ARTICLE; COMMENT
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171128
[Lr] Data última revisão:
171128
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170505
[St] Status:MEDLINE
[do] DOI:10.1002/uog.17478


  8 / 7892 MEDLINE  
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[PMID]:28930821
[Au] Autor:Zhu Y; Zhang GN; Zhang RB; Shi Y; Wang DF; He R
[Ad] Endereço:aDepartment of Ultrasound bDepartment of Gynecologic Oncology, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.
[Ti] Título:Sonographic image of cervix epithelioid trophoblastic tumor coexisting with mucinous adenocarcinoma in a postmenopausal woman: A case report.
[So] Source:Medicine (Baltimore);96(38):e7731, 2017 Sep.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:RATIONALE: Epithelioid trophoblastic tumor (ETT) is a distinctive but rare gestational trophoblastic neoplasia (GTN) composed of chorionic-type intermediate trophoblast cells. Approximately 50% ETT arose from the uterine cervix or lower uterine segment following a previous pregnancy with vaginal bleeding. With its unusual ability to simulate an invasive epithelioid neoplasm, ETT frequently poses a diagnostic challenge, especially involving the uterine cervix. PATIENT CONCERNS: We herein report the case of a 60-year-old female with persistent vaginal bleeding and middle-level elevation of serum human chorionic gonadotropin (hCG). Ultrasound revealed a 3.0 × 2.7 cm well-circumscribed, strongly echogenic lesion in the cervix, with a peripheral pattern of Doppler signals. The enhanced pattern by contrast-enhanced ultrasound displayed strong peripheral enhancement accompanied with globular appearance, then centripetal filling completely, and fading away rapidly. DIAGNOSES: The final pathological diagnosis was ETT accompanying mucinous adenocarcinoma. INTERVENTIONS: Due to the pre-operative evaluation of a presumed IB2 cervix mucinous adenocarcinoma, the patient was treated with 2 courses of neoadjuvant chemotherapy followed by radical hysterectomy. OUTCOMES: The patient is currently disease-free for the past 1 year. LESSONS: This case report demonstrates that sonographic image of tumor shapes and blood flow could be helpful in differentiating ETT from another GTN and enable more accurate diagnosis before treatment.
[Mh] Termos MeSH primário: Adenocarcinoma Mucinoso/diagnóstico por imagem
Neoplasia Intraepitelial Cervical/diagnóstico por imagem
Neoplasias Trofoblásticas/diagnóstico por imagem
Neoplasias do Colo do Útero/diagnóstico por imagem
[Mh] Termos MeSH secundário: Adenocarcinoma Mucinoso/complicações
Neoplasia Intraepitelial Cervical/complicações
Feminino
Seres Humanos
Meia-Idade
Pós-Menopausa
Neoplasias Trofoblásticas/complicações
Ultrassonografia Doppler/métodos
Neoplasias do Colo do Útero/complicações
Hemorragia Uterina/diagnóstico por imagem
Hemorragia Uterina/etiologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:171015
[Lr] Data última revisão:
171015
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170921
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000007731


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[PMID]:28843713
[Au] Autor:Cramer SF; Heller DS
[Ad] Endereço:Department of Pathology, Rochester General Hospital, University of Rochester School of Medicine, Rochester, 14621, NY.
[Ti] Título:Postablation neuroma of the myometrium-a report of 5 cases.
[So] Source:Hum Pathol;67:211-216, 2017 Sep.
[Is] ISSN:1532-8392
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:When hysterectomy is performed for chronic pelvic pain, routine pathology examination often provides no explanation. However, analysis of small uterine nerves using immunostains may help to address this deficiency. Small uterine nerves tend to be sparse or absent in wide areas of normal myometrium. Some studies of uterine nerves have suggested that endometriosis, adenomyosis, and fibroids are not inherently painful, with increased small nerves in the inner uterine wall associated with the history of pelvic pain. Although such areas may appear normal on hematoxylin and eosin (H&E), we have found a subtle inner wall lesion termed inner myometrial elastosis, best detected with trichrome or elastic stains, which may be a reaction to microscopic tears of inner myometrium. Such tears may induce increased inner wall innervation via the generation of nerve growth factor in granulation tissue. In the course of studying uterine nerves with immunostains, we found 5 cases with florid nerve proliferation, after deep endometrial ablation for abnormal uterine bleeding led to increased pelvic pain. We suggest that immunostains for postablation neuromas should be done in hysterectomies when pelvic pain increases after endometrial ablation. This may offer gynecologists and their patients an objective finding with a rational, scientific explanation for the pelvic pain.
[Mh] Termos MeSH primário: Técnicas de Ablação Endometrial/efeitos adversos
Neoplasias do Endométrio/etiologia
Miométrio/cirurgia
Neuroma/etiologia
Neurônios/patologia
Hemorragia Uterina/cirurgia
[Mh] Termos MeSH secundário: Adulto
Biópsia
Dor Crônica/etiologia
Dor Crônica/cirurgia
Neoplasias do Endométrio/patologia
Neoplasias do Endométrio/cirurgia
Feminino
Seres Humanos
Histerectomia
Imuno-Histoquímica
Meia-Idade
Miométrio/inervação
Neuroma/patologia
Neuroma/cirurgia
Neurônios/química
Dor Pós-Operatória/etiologia
Dor Pós-Operatória/cirurgia
Dor Pélvica/etiologia
Dor Pélvica/cirurgia
Resultado do Tratamento
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171016
[Lr] Data última revisão:
171016
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170828
[St] Status:MEDLINE


  10 / 7892 MEDLINE  
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[PMID]:28823573
[Au] Autor:Chen AL; Goldfarb IT; Scourtas AO; Roberts DJ
[Ad] Endereço:Department of Pathology, Massachusetts General Hospital, Boston, MA 02114.
[Ti] Título:The histologic evolution of revealed, acute abruptions.
[So] Source:Hum Pathol;67:187-197, 2017 Sep.
[Is] ISSN:1532-8392
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:There is considerable interest in using pathology to confirm acute abruptions. It has been suggested that pathologic findings can help to determine the timing of abruptions. Because of the dearth of evidence in the literature supporting this claim and its medicolegal implications, we undertook this study to explore further the possibility of timing abruptions by histopathology. We sought to correlate bleeding interval (duration from maternal presentation with vaginal bleeding [revealed abruption] to placental delivery) with placental histopathologic findings. We performed a retrospective review of clinical data and placental pathology from all cases of clinically diagnosed, acute, revealed abruptions at a single, large institution in New England between 2000 and 2015. Cases were identified based on clinical diagnoses, bleeding intervals were calculated from clinical notes, and histologic evaluations were performed by 2 pathologists blinded to the bleeding intervals. A total of 177 cases were analyzed. Of these, 103 (58%) had histologic findings corroborating the clinical diagnosis of abruption. The most frequent finding was maternal surface indentation (51 cases) followed by intravillous hemorrhage (50 cases). The former was also the earliest finding, with a minimum bleeding interval of 4 minutes. In multivariate modeling, plasma cell deciduitis was significantly associated with a longer bleeding interval (median 63 hours). If there were 2 pathologic findings, there was a trend toward a longer bleeding interval. There was modest sensitivity for the pathologic diagnosis of acute revealed abruption. Although there was not a clear, stepwise progression of histologic lesions; the presence of 2 or more findings tended to be seen with longer bleeding intervals. Our results suggest that histologic findings cannot be used to time acute revealed abruptions reliably, and any interpretation of such should be made with caution.
[Mh] Termos MeSH primário: Descolamento Prematuro da Placenta/patologia
Placenta/patologia
[Mh] Termos MeSH secundário: Doença Aguda
Adolescente
Adulto
Biópsia
Boston
Corioamnionite/patologia
Progressão da Doença
Feminino
Hematoma/patologia
Seres Humanos
Modelos Lineares
Meia-Idade
Análise Multivariada
Valor Preditivo dos Testes
Gravidez
Resultado da Gravidez
Reprodutibilidade dos Testes
Estudos Retrospectivos
Fatores de Risco
Fatores de Tempo
Hemorragia Uterina/patologia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171016
[Lr] Data última revisão:
171016
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170822
[St] Status:MEDLINE



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