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[PMID]:29406060
[Au] Autor:Vo A; Kielb SJ
[Ad] Endereço:Department of Urology, Northwestern University Feinberg School of Medicine, 303 East Chicago Avenue, Tarry 16-703, Chicago, IL 60611, USA.
[Ti] Título:Female Voiding Dysfunction and Urinary Incontinence.
[So] Source:Med Clin North Am;102(2):313-324, 2018 Mar.
[Is] ISSN:1557-9859
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Female voiding dysfunction and incontinence are common in the general population and symptoms have been shown to have a significant negative impact on health-related quality of life. This article highlights the epidemiology, evaluation, diagnosis, pharmacologic therapies, and surgical treatment for overactive bladder, stress urinary incontinence, and urogenital fistulas.
[Mh] Termos MeSH primário: Bexiga Urinária Hiperativa
Incontinência Urinária
Fístula Vaginal
[Mh] Termos MeSH secundário: Feminino
Seres Humanos
Bexiga Urinária Hiperativa/complicações
Bexiga Urinária Hiperativa/terapia
Incontinência Urinária/etiologia
Incontinência Urinária/fisiopatologia
Incontinência Urinária/terapia
Fístula Vaginal/complicações
Fístula Vaginal/cirurgia
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180208
[Lr] Data última revisão:
180208
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180207
[St] Status:MEDLINE


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[PMID]:28355089
[Au] Autor:Botsikas D; Pluchino N; Kalovidouri A; Platon A; Montet X; Dallenbach P; Poletti PA
[Ad] Endereço:1 Division of Radiology, Department of Imaging and Medical Information Sciences, Geneva University Hospitals, Geneva, Switzerland.
[Ti] Título:CT vaginography: a new CT technique for imaging of upper and middle vaginal fistulas.
[So] Source:Br J Radiol;90(1073):20160947, 2017 May.
[Is] ISSN:1748-880X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: Different types of vaginal fistulas is a relatively uncommon condition in the Western world but very frequent in developing countries. In the past, conventional vaginography was the radiological examination of choice for exploring this condition. CT and MRI are now both used for this purpose. Our objective was to test the feasibility and to explore the potential role of a new CT imaging technique implementing vaginal introitus obstruction and opacification of the vagina with iodine contrast agent, to show patency of a fistula. METHODS: We describe the technical protocol of CT-vaginography as performed in Geneva University Hospitals, including vaginal catheterization with a Foley catheter and obstruction of the introitus by inflating the balloon of the catheter. We also report three cases of patients with suspected vaginal fistula who underwent CT-vaginography. RESULTS: The examinations were technically successful. In one patient, it revealed the presence of fistulous pathways from the vaginal fornix along the bilateral infected surgical prostheses. In a second patient, it showed a fistula between the vagina and the necrotic cavity of a recurrent cervical cancer. In a third patient, it proved the absence of a suspected vaginal fistula. CONCLUSION: CT-vaginography is a technically feasible CT protocol that provides anatomical and functional information on clinically suspected vaginal fistulas. Advances in knowledge: After the abandon of conventional vaginography in the era of transaxial imaging, the current modalities of imaging vaginal fistulas provide excellent anatomical detail but less functional information concerning the permeability of a vaginal fistulous pathway. We propose the use of CT-vaginography, a technical protocol that we describe in detail.
[Mh] Termos MeSH primário: Tomografia Computadorizada por Raios X/métodos
Vagina/diagnóstico por imagem
Fístula Vaginal/diagnóstico por imagem
[Mh] Termos MeSH secundário: Estudos de Viabilidade
Feminino
Seres Humanos
Meia-Idade
Cateterismo Urinário
[Pt] Tipo de publicação:CLINICAL TRIAL; JOURNAL ARTICLE
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170922
[Lr] Data última revisão:
170922
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170330
[St] Status:MEDLINE
[do] DOI:10.1259/bjr.20160947


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[PMID]:28288664
[Au] Autor:Mwanri L; Gatwiri GJ
[Ad] Endereço:Discipline of Public Health, Faculty of Medicine, Nursing and Health Sciences, Flinders University, Level 2, Health Sciences Building, Registry Road, Bedford Park, South Australia, 5042, Australia. lillian.mwanri@flinders.edu.au.
[Ti] Título:Injured bodies, damaged lives: experiences and narratives of Kenyan women with obstetric fistula and Female Genital Mutilation/Cutting.
[So] Source:Reprod Health;14(1):38, 2017 Mar 14.
[Is] ISSN:1742-4755
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: It is well acknowledged that Female Genital Mutilation/Cutting (FGM/C/C) leads to medical, psychological and sociocultural sequels. Over 200 million cases of FGM/C exist globally, and in Kenya alone, a total of 12,418,000 (28%) of women have undergone FGM/C, making the practice not only a significant national, but also a global health catastrophe. FGM/C is rooted in patriarchal and traditional cultures as a communal experience signifying a transition from girlhood to womanhood. The conversations surrounding FGM/C have been complicated by the involvement of women themselves in perpetuating the practice. METHODS: A qualitative inquiry employing face-to-face, one-on-one, in-depth semi-structured interviews was used in a study that included 30 women living with obstetric fistulas in Kenya. Using the Social Network Framework and a feminist analysis we present stories of Kenyan women who had developed obstetric fistulas following prolonged and obstructed childbirth. RESULTS: Of the 30 participants, three women reported that health care workers informed them that FGM/C was one of the contributing factors to their prolonged and obstructed childbirth. They reported serious obstetric complications including: the development of obstetric fistulas, lowered libido, poor quality of life and maternal and child health outcomes, including death. Fistula and subsequent loss of bodily functionalities such as uncontrollable leakage of body wastes, was reported by the women to result in rejection by spouses, families, friends and communities. Rejection further led to depression, loss of work, increased sense of apathy, lowered self-esteem and image, as well as loss of identity and communal sociocultural cohesion. CONCLUSION: FGM/C is practised in traditional, patriarchal communities across Africa. Although the practice aims to bind community members and to celebrate a rite of passage; it may lead to harmful health and social consequences. Some women with fistula report their fistula was caused by FGM/C. Concerted efforts which embrace feminist understandings of society, as well as multi-sectoral, multidisciplinary and community development approaches need to be employed to address FGM/C, and to possibly reduce cases of obstetric fistulas in Kenya and beyond. Both government and non-government organisations need to be involved in making legislative, gender sensitive policies that protect women from FGM/C. In addition, the policy makers need to be in the front line to improve the lives of women who endured the consequences of FGM/C.
[Mh] Termos MeSH primário: Circuncisão Feminina/efeitos adversos
Conhecimentos, Atitudes e Prática em Saúde
Procedimentos Cirúrgicos Obstétricos/efeitos adversos
Qualidade de Vida
Fístula Vaginal/etiologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Feminino
Seres Humanos
Quênia
Meia-Idade
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170504
[Lr] Data última revisão:
170504
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170315
[St] Status:MEDLINE
[do] DOI:10.1186/s12978-017-0300-y


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[PMID]:28140615
[Au] Autor:Heller A; Hannig A
[Ad] Endereço:a Department of Anthropology , University of Maryland at College Park , College Park , MD , USA.
[Ti] Título:Unsettling the fistula narrative: cultural pathology, biomedical redemption, and inequities of health access in Niger and Ethiopia.
[So] Source:Anthropol Med;24(1):81-95, 2017 Apr.
[Is] ISSN:1469-2910
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Obstetric fistula, a maternal childbirth injury that results in chronic incontinence, affects an estimated one million women in the global south. In the course of media and donor coverage on this condition, fistula sufferers have been branded as 'child brides' who, following the onset of their incontinence, become social pariahs and eventually find physical and social redemption through surgical repair. This narrative framing pits the violence of 'culture' against the potency of biomedical salvation. Based on over two years of ethnographic research at fistula repair centres in Niger and Ethiopia, this paper challenges this narrative and argues that most women with obstetric fistula remain embedded in social relations, receive continued familial support, and, unexpectedly, experience ambiguous surgical outcomes. This paper interrogates the existing logics of the fistula narrative that have had the unintended effects of obscuring global structural inequalities and diverting attention away from systemic health access reforms.
[Mh] Termos MeSH primário: Acesso aos Serviços de Saúde
Disparidades em Assistência à Saúde
Complicações do Trabalho de Parto/etnologia
Incontinência Urinária/etnologia
Fístula Vaginal/etnologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Antropologia Médica
Etiópia
Feminino
Reforma dos Serviços de Saúde
Seres Humanos
Masculino
Níger
Complicações do Trabalho de Parto/psicologia
Complicações do Trabalho de Parto/cirurgia
Gravidez
Autocuidado/psicologia
Apoio Social
Fatores Socioeconômicos
Resultado do Tratamento
Incontinência Urinária/etiologia
Incontinência Urinária/psicologia
Incontinência Urinária/cirurgia
Fístula Vaginal/etiologia
Fístula Vaginal/psicologia
Fístula Vaginal/cirurgia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170320
[Lr] Data última revisão:
170320
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170201
[St] Status:MEDLINE
[do] DOI:10.1080/13648470.2016.1249252


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[PMID]:27889268
[Au] Autor:Wen Y; Althans AR; Brady JT; Dosokey EM; Choi D; Nishtala M; Delaney CP; Steele SR
[Ad] Endereço:Department of Surgery, Division of Colorectal Surgery, University Hospitals Cleveland Medical Center, 11100 Euclid Avenue, Cleveland, OH 44106, USA.
[Ti] Título:Evaluating surgical management and outcomes of colovaginal fistulas.
[So] Source:Am J Surg;213(3):553-557, 2017 Mar.
[Is] ISSN:1879-1883
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Colovaginal fistula is a rare condition associated with significant morbidity. The literature characterizing colovaginal fistula repair is sparse. We present our institution's experience treating colovaginal fistulas. METHODS: A retrospective review of all patients surgically treated for colovaginal fistula between 2005 and 2015 was performed. Patient demographics, intra-operative details, and post-operative outcomes were reviewed. RESULTS: We identified 27 patients with a mean age of 71 (±13) and BMI of 30 (±9). The most common etiology for fistula was diverticulitis (n = 24, 89%). A laparoscopic approach was initiated in 19 patients (70%) and an open approach for 8 (30%) with 8 patients converted from laparoscopy to open (42%). At a mean follow-up of 18 months (±21), there were no recurrences. CONCLUSION: We present one of the largest series of the surgical management of colovaginal fistulas. Although our conversion rate was high, we recommend a laparoscopic approach be utilized when feasible.
[Mh] Termos MeSH primário: Fístula Intestinal/cirurgia
Fístula Vaginal/cirurgia
[Mh] Termos MeSH secundário: Idoso
Conversão para Cirurgia Aberta/estatística & dados numéricos
Doença Diverticular do Colo/complicações
Feminino
Seguimentos
Seres Humanos
Fístula Intestinal/etiologia
Laparoscopia/estatística & dados numéricos
Complicações Pós-Operatórias
Reoperação/estatística & dados numéricos
Estudos Retrospectivos
Fístula Vaginal/etiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170417
[Lr] Data última revisão:
170417
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:161128
[St] Status:MEDLINE


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[PMID]:27745889
[Au] Autor:Rosen DR; Hwang GS; Ault GT; Ortega AE; Cologne KG
[Ad] Endereço:Division of Colorectal Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
[Ti] Título:Operative management of diverticulitis in a tertiary care center.
[So] Source:Am J Surg;214(1):37-41, 2017 Jul.
[Is] ISSN:1879-1883
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Diverticulitis has become a medically managed disease process; the indications and timing of surgical intervention have evolved. METHODS: We retrospectively reviewed all patients who underwent surgical intervention due to diverticular disease by the Division of Colon and Rectal Surgery from 2012 to 2014. RESULTS: Ninety-eight surgeries were performed. Indications included colovesicular fistula, multiple recurrences of diverticulitis, medically refractory diverticulitis, stricture, abscess, colocutaneous fistula, and colovaginal fistula. Average length of stay was 5.7 ± 5.9 days (range, 1 to 51). Eighteen patients (18%) required an ostomy. Postoperative complications occurred in 18% of patients, including anastomotic leak (3.3%), wound infection (7.1%), acute kidney injury (5.1%), and urinary tract infection (2.0%). Thirty-day readmission rate was 7.2%; unplanned 30-day reoperation rate was 3.1%. There were no deaths. CONCLUSIONS: The type of patient undergoing surgery for diverticulitis has changed, with selection bias toward chronic, advanced disease due to the proliferation of medical management strategies.
[Mh] Termos MeSH primário: Doença Diverticular do Colo/cirurgia
[Mh] Termos MeSH secundário: Abscesso/cirurgia
Constrição Patológica/cirurgia
Fístula Cutânea/cirurgia
Feminino
Seres Humanos
Fístula Intestinal/cirurgia
Tempo de Internação/estatística & dados numéricos
Masculino
Meia-Idade
Estomia/estatística & dados numéricos
Readmissão do Paciente/estatística & dados numéricos
Complicações Pós-Operatórias
Recidiva
Reoperação/estatística & dados numéricos
Estudos Retrospectivos
Centros de Atenção Terciária
Fístula Vaginal/cirurgia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170821
[Lr] Data última revisão:
170821
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:161018
[St] Status:MEDLINE


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[PMID]:27680693
[Au] Autor:Mafo Degge H; Hayter M; Laurenson M
[Ad] Endereço:Faculty of Health and Social Care, University of Hull, Hull, UK.
[Ti] Título:An integrative review on women living with obstetric fistula and after treatment experiences.
[So] Source:J Clin Nurs;26(11-12):1445-1457, 2017 Jun.
[Is] ISSN:1365-2702
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:AIMS AND OBJECTIVES: To review literature on the experiences of women with obstetric fistula, their lived experiences after treatment; and to provide evidence for future research. BACKGROUND: Obstetric fistula is an injury most commonly resulting from a prolonged labour. Long eradicated in developed countries, obstetric fistula remains a public health issue in sub-Saharan Africa and Asia. This is a highly stigmatised health condition, and an understanding of the women's experience is required to inform holistic approaches for care and prevention. DESIGN: A search of literature was conducted on databases of EBSCO host (Academic Search Premier, MEDLINE, PsychINFO, CINAHL), Web of Science; and websites of international organizations such as Women's Dignity Project and EngenderHealth. Keywords, Inclusion and exclusion criteria were defined and 25 articles published between 2004 to January 2015 were identified. METHODS: An integrative review of 25 articles was carried out. RESULTS: Three broad themes were identified: Challenges of living with fistula; treatment and care experiences; and reintegration experiences of women after fistula repair. CONCLUSIONS: Living with a fistula presents multidimensional consequences affecting women, families and communities. Accessing treatment is difficult and there are no standardised treatment packages. Surgical repairs were variable in their success rate. Some authors claim women resume normal lives irrespective of their continence status, whilst others claim they face discrimination despite being continent thereby hindering reintegration. Quality of life is diminished for those remaining incontinent. Post repair psychosocial support services are beneficial for reintegration, but research on programme benefits is limited. Therefore further research is required to support its benefits; and for policy development to meet care provision for women with fistula. RELEVANCE TO CLINICAL PRACTICE: The review provides insights into avenues of improving care provision and delivery by health professionals and policy makers. It also exposes areas that need further research for quality care provision.
[Mh] Termos MeSH primário: Parto Obstétrico/efeitos adversos
Qualidade de Vida
Estereotipagem
Fístula Vaginal/psicologia
[Mh] Termos MeSH secundário: África ao Sul do Saara
Ásia
Feminino
Seres Humanos
Gravidez
Apoio Social
Fístula Vaginal/terapia
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170728
[Lr] Data última revisão:
170728
[Sb] Subgrupo de revista:N
[Da] Data de entrada para processamento:160930
[St] Status:MEDLINE
[do] DOI:10.1111/jocn.13590


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[PMID]:27525690
[Au] Autor:Clifton MM; Goldman HB
[Ad] Endereço:Department of Urology, 9500 Euclid Avenue/ Q10-1, Cleveland, OH, 44195, USA. marisameyerclifton@gmail.com.
[Ti] Título:Urethrovaginal fistula closure.
[So] Source:Int Urogynecol J;28(1):157-158, 2017 Jan.
[Is] ISSN:1433-3023
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION AND HYPOTHESIS: In the developed world, urethrovaginal fistulas are most the likely the result of iatrogenic injury. These fistulas are quite rare. Proper surgical repair requires careful dissection and tension-free closure. The objective of this video is to demonstrate the identification and surgical correction of an urethrovaginal fistula. METHODS: The case presented is of a 59-year-old woman with a history of pelvic organ prolapse and symptomatic stress urinary incontinence who underwent vaginal hysterectomy, anterior colporrhaphy, posterior colporrhaphy, and synthetic sling placement. Postoperatively, she developed a mesh extrusion and underwent sling excision. After removal of her synthetic sling, she began to experience continuous urinary incontinence. Physical examination and cystourethroscopy demonstrated an urethrovaginal fistula at the midurethra. Options were discussed and the patient wished to undergo transvaginal fistula repair. RESULTS: The urethrovaginal fistula was intubated with a Foley catheter. The fistula tract was isolated and removed. The urethra was then closed with multiple tension-free layers. This video demonstrates several techniques for identifying and subsequently repairing an urethrovaginal fistula. Additionally, it demonstrates the importance of tension-free closure. CONCLUSIONS: Urethrovaginal fistulas are rare. They should be repaired with careful dissection and tension-free closure.
[Mh] Termos MeSH primário: Dissecação/métodos
Doenças Uretrais/cirurgia
Fístula Urinária/cirurgia
Incontinência Urinária/cirurgia
Fístula Vaginal/cirurgia
[Mh] Termos MeSH secundário: Feminino
Seres Humanos
Meia-Idade
Slings Suburetrais
Resultado do Tratamento
Doenças Uretrais/complicações
Fístula Urinária/complicações
Incontinência Urinária/etiologia
Fístula Vaginal/complicações
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; VIDEO-AUDIO MEDIA
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170920
[Lr] Data última revisão:
170920
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160816
[St] Status:MEDLINE
[do] DOI:10.1007/s00192-016-3111-8


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[PMID]:27736158
[Au] Autor:Kim M; Hong B; Park HK
[Ad] Endereço:Department of Urology, Asan Medical Center, University of Ulsan College of Medicine , Seoul, Republic of Korea.
[Ti] Título:Long-Term Outcomes of Double-Layered Polytetrafluoroethylene Membrane-Covered Self-Expandable Segmental Metallic Stents (Uventa) in Patients with Chronic Ureteral Obstructions: Is It Really Safe?
[So] Source:J Endourol;30(12):1339-1346, 2016 Dec.
[Is] ISSN:1557-900X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PURPOSE: To evaluate the long-term clinical efficacy and safety of double-layered polytetrafluoroethylene membrane-covered self-expandable segmental metallic stents (Uventa) in patients with chronic ureteral obstruction. MATERIALS AND METHODS: In a retrospective study, a total of 50 ureter units (44 patients) with chronic obstructions were included from July 2010 to May 2015. Indications for Uventa placement were primary stenting for malignant ureteral obstruction, failed conventional polymeric Double-J stent (PS), or percutaneous nephrostomy (PCN) technique, with comorbidities or fears limiting PS/PCN changes, or with irritation or pain due to PS/PCN. Patients underwent Uventa stent placement using the antegrade or retrograde approach. RESULTS: There were no immediate procedure-related complications, and all stents were placed in the proper sites. During the median follow-up of 30.9 (interquartile range [IQR], 8.1-49.0) months, the primary (no obstruction and no additional intervention) and overall success (no obstruction and no additional intervention except supplementary Uventa) was 30.0% and 34.0%, respectively. Moreover, 14 of 50 ureter units (28.0%) experienced major complications (≥Clavien-Dindo class IIIb), such as ureteroarterial fistula (three cases, 6.0%), ureteroenteric fistula (three, 6.0%), ureterovaginal fistula (one, 2.0%), ureter perforation (one, 2.0%), uncontrollable bleeding (one, 2.0%), and complete obstruction (five, 10.0%). On univariate analysis, major complications were associated with female (odds ratio [OR] = 6.000), cervical cancer (OR = 4.667), ureteral stricture length (≥6.0 cm, OR = 4.583), and placement duration (≥24.0 months, OR = 20.429; all p < 0.05). CONCLUSIONS: In long-term follow-up, the Uventa stent demonstrated poor treatment outcomes with frequent major complications in patients with chronic ureteral obstructions.
[Mh] Termos MeSH primário: Metais/efeitos adversos
Politetrafluoretileno
Stents/efeitos adversos
Obstrução Ureteral/etiologia
Obstrução Ureteral/cirurgia
[Mh] Termos MeSH secundário: Adulto
Idoso
Materiais Revestidos Biocompatíveis
Progressão da Doença
Feminino
Seguimentos
Seres Humanos
Masculino
Meia-Idade
Nefrostomia Percutânea/métodos
Segurança do Paciente
Polímeros
Desenho de Prótese
Radiografia Abdominal
Estudos Retrospectivos
Fatores de Risco
Resultado do Tratamento
Ureter
Doenças Ureterais/complicações
Fístula Urinária/complicações
Neoplasias do Colo do Útero/complicações
Fístula Vaginal
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Coated Materials, Biocompatible); 0 (Metals); 0 (Polymers); 9002-84-0 (Polytetrafluoroethylene)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170809
[Lr] Data última revisão:
170809
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161014
[St] Status:MEDLINE


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[PMID]:27624676
[Au] Autor:Hayashi C; Takada S; Kasuga A; Shinya K; Watanabe M; Kano H; Takayama T
[Ad] Endereço:Department of Obstetrics and Gynecology, Nihon University School of Medicine, Tokyo, Japan. hayashi.chuyu@nihon-u.ac.jp.
[Ti] Título:Sigmoid-vaginal fistula during bevacizumab treatment diagnosed by fistulography.
[So] Source:J Clin Pharm Ther;41(6):725-726, 2016 Dec.
[Is] ISSN:1365-2710
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:WHAT IS KNOWN AND OBJECTIVE: There have been several reports describing rectovaginal fistula development after bevacizumab treatment, and these fistulas were diagnosed by CT scan or colonoscopy. We report a case of sigmoid-vaginal fistula diagnosed by fistulography. CASE DESCRIPTION: The case is a 53-year-old woman who was treated for chronic myelogenous leukaemia and gynaecological cancers 8 years previously. At 52 years of age, she was diagnosed with colon cancer and had a partial colectomy performed. One year after surgery, colon cancer recurred, and she was treated with anticancer agents, including bevacizumab. During chemotherapy, she complained of a foul smelling discharge from the vagina. Fistulography revealed a sigmoid-vaginal fistula. WHAT IS NEW AND CONCLUSION: This is the first report of vaginal fistulography performed on a patient who was treated with bevacizumab. Fistulography may be useful for detecting sigmoid-vaginal fistula.
[Mh] Termos MeSH primário: Inibidores da Angiogênese/efeitos adversos
Bevacizumab/efeitos adversos
Colo Sigmoide/efeitos dos fármacos
Fístula Vaginal/induzido quimicamente
[Mh] Termos MeSH secundário: Inibidores da Angiogênese/uso terapêutico
Bevacizumab/uso terapêutico
Neoplasias do Colo/tratamento farmacológico
Feminino
Seres Humanos
Meia-Idade
Recidiva Local de Neoplasia/tratamento farmacológico
[Pt] Tipo de publicação:CASE REPORTS
[Nm] Nome de substância:
0 (Angiogenesis Inhibitors); 2S9ZZM9Q9V (Bevacizumab)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170426
[Lr] Data última revisão:
170426
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160915
[St] Status:MEDLINE
[do] DOI:10.1111/jcpt.12454



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