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[PMID]:29424517
[Au] Autor:Karchmer-Krivitzky S; Espinosa-Fernández R; Sánchez-Aranda A; LópezRioja MJ; Monzalbo-Núñez D
[Ti] Título:[Peripartum cardiomyopathy: a case report].
[Ti] Título:Miocardiopatía periparto: reporte de un caso..
[So] Source:Ginecol Obstet Mex;84(8):542-9, 2016 08.
[Is] ISSN:0300-9041
[Cp] País de publicação:Mexico
[La] Idioma:spa
[Ab] Resumo:Background: Peripartum cardiomyopathy also known as cardiomyopathy associated with pregnancy, is rarely a cause of heart failure, it affects pregnant or puerperal women in the first 5 months. Although the first case reported was in 1849, it was recognized until 1930. In 2010 the European Society of Cardiology Working Group on peripartum cardiomyopathy, defined this pathology as an idiopathic cardiomyopathy that affects pregnant women between the third trimester and five months after delivery. Characterized by a left ventricular failure with an ejection fraction of ≤45% and an end-diastolic dimension ≥2.7 cm/m2 , in absence of an identifiable cause of heart failure. Case report: We report a case of a 39-year-old patient, diagnosed with a peripartum cardiomyopathy in the early puerperium, characterized by hypertension, tachycardia, dyspnea and oxygen desaturation. The transesophageal echocardiogram reported heart failure, a hypokinetic left ventricle and a ventricular failure with an ejection fraction <40%. We could not identify an other cause to justify heart failure. Multidisciplinary management was administered successfully. Conclusion: The importance of this article relies in the fact that eripartum cardiomyopathy has a high morbidity and mortality. The impact of this pathology is unknow in our country. Here we establish and discuss the multidisciplinary management held in our hospital with this specific patient in order to improve the prognosis on future occasions.
[Mh] Termos MeSH primário: Cardiomiopatias/diagnóstico
Insuficiência Cardíaca/diagnóstico
Complicações Cardiovasculares na Gravidez/diagnóstico
[Mh] Termos MeSH secundário: Adulto
Cardiomiopatias/fisiopatologia
Cardiomiopatias/terapia
Ecocardiografia Transesofagiana
Feminino
Insuficiência Cardíaca/fisiopatologia
Insuficiência Cardíaca/terapia
Seres Humanos
Período Periparto
Gravidez
Complicações Cardiovasculares na Gravidez/fisiopatologia
Complicações Cardiovasculares na Gravidez/terapia
Disfunção Ventricular Esquerda/diagnóstico
Disfunção Ventricular Esquerda/fisiopatologia
Disfunção Ventricular Esquerda/terapia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180301
[Lr] Data última revisão:
180301
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180210
[St] Status:MEDLINE


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[PMID]:29205581
[Au] Autor:Boulanger H; Ahriz Saksi S; Ekoukou D
[Ad] Endereço:Department of Nephrology and Dialysis, Clinique de l'Estrée, 35 rue d'Amiens, 93240, Stains, France.
[Ti] Título:Alternative explanations for linking chronic hypertension to adverse pregnancy outcome.
[So] Source:Ultrasound Obstet Gynecol;50(6):805-806, 2017 12.
[Is] ISSN:1469-0705
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Complicações Cardiovasculares na Gravidez
Resultado da Gravidez
[Mh] Termos MeSH secundário: Feminino
Seres Humanos
Hipertensão
Gravidez
[Pt] Tipo de publicação:LETTER; COMMENT
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180123
[Lr] Data última revisão:
180123
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171206
[St] Status:MEDLINE
[do] DOI:10.1002/uog.18921


  3 / 14919 MEDLINE  
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[PMID]:29202781
[Au] Autor:Cooper K; Brown S
[Ad] Endereço:Department Obstetrics, Gynecology and Reproductive Sciences, Burlington, VT, 05401, USA. kylie.cooper@uvmhealth.org.
[Ti] Título:ACTA2 mutation and postpartum hemorrhage: a case report.
[So] Source:BMC Med Genet;18(1):143, 2017 12 04.
[Is] ISSN:1471-2350
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: ACTA2 encodes smooth muscle specific α-actin, a critical component or the contractile complex of vascular smooth muscle. Mutations in ACTA2 are the most common genetic cause of thoracic aortic aneurysm, and are also the cause of other disorders, including Moyamoya disease, coronary artery disease and stroke as well as Multisystemic Smooth Muscle Dysfunction Syndrome. We note that ACTA2 is also expressed in uterine smooth muscle, and this raises the possibility that women harboring ACTA2 mutations might exhibit uterine smooth muscle dysfunction. CASE PRESENTATION: We present a young woman whose ACTA2 mutation was ascertained during pregnancy because of her father's history of dissecting aneurysms. She was delivered at full term by cesarean section and subsequently had severe uterine hemorrhage due to uterine atony. Although her atony was successfully treated with uterotonic medications, she required blood transfusion. CONCLUSIONS: This case raises the possibility that women with ACTA2 mutations may be at risk of uterine muscle dysfunction and hemorrhage. Obstetricians should be alerted to and prepared for this possibility.
[Mh] Termos MeSH primário: Actinas/genética
Mutação de Sentido Incorreto
Hemorragia Pós-Parto/genética
[Mh] Termos MeSH secundário: Adulto
Substituição de Aminoácidos
Aneurisma Dissecante/complicações
Aneurisma Dissecante/genética
Feminino
Predisposição Genética para Doença
Seres Humanos
Recém-Nascido
Masculino
Gravidez
Complicações Cardiovasculares na Gravidez/genética
Inércia Uterina/genética
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (ACTA2 protein, human); 0 (Actins)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171231
[Lr] Data última revisão:
171231
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171206
[St] Status:MEDLINE
[do] DOI:10.1186/s12881-017-0505-5


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[PMID]:29187940
[Au] Autor:Charfeddine S; Abid D; Triki F; Abid L; Kammoun S; Frikha I
[Ad] Endereço:Department of Cardiology, Hedi Chaker University Hospital, Sfax, Tunisia.
[Ti] Título:Unusual case of ruptured sinus of valsalva aneurysm in a pregnant woman.
[So] Source:Pan Afr Med J;27:271, 2017.
[Is] ISSN:1937-8688
[Cp] País de publicação:Uganda
[La] Idioma:eng
[Ab] Resumo:Sinus of Valsalva aneurysms are extremely rare, and usually of a congenital nature. There are few documented cases of this condition during pregnancy, which renders unclear the therapeutic options. We here report the case of a 26 years old pregnant woman who was referred to our cardiac center for the evaluation of a heart murmur. The two-dimensional transthoracic echocardiography allowed quickly to establishthe diagnosis of a ruptured sinus of Valsalva aneurysm into the right ventricle. A successful surgical correction of the ruptured aneurysm was performed with patch repair.
[Mh] Termos MeSH primário: Aneurisma Aórtico/diagnóstico por imagem
Ruptura Aórtica/diagnóstico por imagem
Complicações Cardiovasculares na Gravidez/diagnóstico por imagem
Seio Aórtico/diagnóstico por imagem
[Mh] Termos MeSH secundário: Adulto
Aneurisma Aórtico/cirurgia
Ruptura Aórtica/cirurgia
Ecocardiografia/métodos
Feminino
Sopros Cardíacos/diagnóstico
Ventrículos do Coração/diagnóstico por imagem
Seres Humanos
Gravidez
Complicações Cardiovasculares na Gravidez/cirurgia
Seio Aórtico/cirurgia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171219
[Lr] Data última revisão:
171219
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171201
[St] Status:MEDLINE
[do] DOI:10.11604/pamj.2017.27.271.9741


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[PMID]:29173613
[Au] Autor:Steckham KE; Bhagra CJ; Siu SC; Silversides CK
[Ad] Endereço:Department of Medicine, Obstetric Medicine and Pregnancy and Heart Disease Programs, Mount Sinai Hospital and University Health Network, University of Toronto, Toronto, Ontario, Canada.
[Ti] Título:Pregnancy in Women With Repaired Truncus Arteriosus: A Case Series.
[So] Source:Can J Cardiol;33(12):1737.e1-1737.e3, 2017 Dec.
[Is] ISSN:1916-7075
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Pregnancy in women with repaired truncus arteriosus (TA) is rare. We report the outcomes of 8 pregnancies in 4 women with surgically repaired TA. None of the women had adverse cardiac events during pregnancy. Two pregnancies, both in the same woman, were complicated by hypertensive disorders of pregnancy. The birth weight was less than the 10th percentile for gestational age in 3 pregnancies. Although women with repaired TA can do well during pregnancy, they require careful preconception assessment and surveillance.
[Mh] Termos MeSH primário: Procedimentos Cirúrgicos Cardíacos
Complicações Cardiovasculares na Gravidez
Persistência do Tronco Arterial/cirurgia
Tronco Arterial/cirurgia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Feminino
Seguimentos
Seres Humanos
Gravidez
Resultado da Gravidez
Estudos Retrospectivos
Tronco Arterial/diagnóstico por imagem
Persistência do Tronco Arterial/diagnóstico
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171204
[Lr] Data última revisão:
171204
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171128
[St] Status:MEDLINE


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[PMID]:28974635
[Au] Autor:Aguiar de Sousa D; Canhão P; Crassard I; Coutinho J; Arauz A; Conforto A; Béjot Y; Giroud M; Ferro JM; ISCVT-2-PREGNANCY Investigators
[Ad] Endereço:From the Department of Neurology, Hospital de Santa Maria, University of Lisbon, Portugal (D.A.d.S., P.C., J.M.F.); Instituto de Medicina Molecular, Lisbon, Portugal (D.A.d.S., P.C., J.M.F.); Department of Neurology, Hôpital Lariboisière, Paris, France (I.C.); Department of Neurology, Academic Medic
[Ti] Título:Safety of Pregnancy After Cerebral Venous Thrombosis: Results of the ISCVT (International Study on Cerebral Vein and Dural Sinus Thrombosis)-2 PREGNANCY Study.
[So] Source:Stroke;48(11):3130-3133, 2017 Nov.
[Is] ISSN:1524-4628
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND AND PURPOSE: Pregnancy is associated with increased risk of venous thrombotic events, including cerebral venous thrombosis. We aimed to study the complications and outcome of subsequent pregnancies in women with previous cerebral venous thrombosis. METHODS: Follow-up study of women with acute cerebral venous thrombosis at childbearing age included in a previously described cohort (International Study of Cerebral Vein and Dural Sinus Thrombosis). Patients were interviewed by local neurologists to assess rate of venous thrombotic events, pregnancy outcomes, and antithrombotic prophylaxis during subsequent pregnancies. RESULTS: A total of 119 women were included, with a median follow-up of 14 years. Eighty-two new pregnancies occurred in 47 women. In 83% (68 of 82), some form of antithrombotic prophylaxis was given during at least 1 trimester of pregnancy or puerperium. Venous thrombotic events occurred in 3 pregnancies, including 1 recurrent cerebral venous thrombosis. Two of the 3 women were on prophylactic low-molecular-weight heparin at the time of the event. Outcomes of pregnancies were 51 full-term newborns, 9 preterm births, 2 stillbirths, and 20 abortions (14 spontaneous). CONCLUSIONS: In women with prior cerebral venous thrombosis, recurrent venous thrombotic events during subsequent pregnancies are infrequent.
[Mh] Termos MeSH primário: Veias Cerebrais
Fibrinolíticos/administração & dosagem
Heparina de Baixo Peso Molecular/administração & dosagem
Trombose Intracraniana/prevenção & controle
Complicações Cardiovasculares na Gravidez/prevenção & controle
Resultado da Gravidez
[Mh] Termos MeSH secundário: Adulto
Feminino
Seguimentos
Seres Humanos
Trombose Intracraniana/epidemiologia
Trombose Intracraniana/fisiopatologia
Gravidez
Complicações Cardiovasculares na Gravidez/epidemiologia
Complicações Cardiovasculares na Gravidez/fisiopatologia
Recidiva
[Pt] Tipo de publicação:CLINICAL TRIAL; JOURNAL ARTICLE; MULTICENTER STUDY
[Nm] Nome de substância:
0 (Fibrinolytic Agents); 0 (Heparin, Low-Molecular-Weight)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171026
[Lr] Data última revisão:
171026
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171005
[St] Status:MEDLINE
[do] DOI:10.1161/STROKEAHA.117.018829


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[PMID]:28957562
[Au] Autor:Sonesson SE; Hedlund M; Ambrosi A; Wahren-Herlenius M
[Ad] Endereço:Pediatric Cardiology Unit, Department of Women's and Children's Health.
[Ti] Título:Factors influencing fetal cardiac conduction in anti-Ro/SSA-positive pregnancies.
[So] Source:Rheumatology (Oxford);56(10):1755-1762, 2017 Oct 01.
[Is] ISSN:1462-0332
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Objectives: Congenital heart block (CHB) develops in 1-2% of anti-Ro/SSA-positive pregnancies and has a recurrence rate of 12-20%, which indicates that factors other than maternal autoantibodies are crucial for CHB to occur. Here, we aimed to evaluate the influence of factors previously associated with CHB on the occurrence of milder forms of fetal cardiac conduction disturbances, shown to occur in up to 30% of anti-Ro/SSA-positive pregnancies, and on neonatal outcome in a large cohort of prospectively followed pregnancies. Methods: The association of maternal age, season of the year and history of atrioventricular block (AVB) with the development of fetal Doppler and neonatal ECG conduction disturbances was evaluated in 212 anti-Ro52/SSA-positive singleton pregnancies. Results: Maternal age was significantly higher in AVB II-III pregnancies but was not correlated with fetal AV time intervals in fetuses without signs of AVB II-III. AV time intervals of fetuses surveilled during the winter were significantly longer than those of fetuses surveilled during the summer. Fetal AV time intervals in consecutive pregnancies from the same women were significantly correlated. A history of AVB II-III was associated with significantly longer AV time intervals, and AVB I-III was observed at birth in 38% of babies born after a sibling with abnormal fetal AV conduction. Conclusion: Our study shows that AV time intervals in anti-Ro/SSA antibody-exposed fetuses during the CHB risk period are influenced by the season of the year, and reveals that the recurrence of conduction disturbances in antibody-exposed fetuses is higher than previously reported when milder forms are taken into account.
[Mh] Termos MeSH primário: Anticorpos Antinucleares
Bloqueio Atrioventricular/fisiopatologia
Coração Fetal/fisiopatologia
Bloqueio Cardíaco/congênito
Complicações Cardiovasculares na Gravidez/imunologia
Estações do Ano
[Mh] Termos MeSH secundário: Adulto
Anticorpos Antinucleares/sangue
Bloqueio Atrioventricular/congênito
Autoanticorpos/sangue
Ecocardiografia Doppler/métodos
Feminino
Coração Fetal/diagnóstico por imagem
Bloqueio Cardíaco/diagnóstico por imagem
Bloqueio Cardíaco/fisiopatologia
Seres Humanos
Gravidez
Complicações Cardiovasculares na Gravidez/sangue
Complicações Cardiovasculares na Gravidez/diagnóstico por imagem
Resultado da Gravidez
Estudos Prospectivos
Ribonucleoproteínas/imunologia
Fatores de Risco
Ultrassonografia Pré-Natal/métodos
[Pt] Tipo de publicação:EVALUATION STUDIES; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antibodies, Antinuclear); 0 (Autoantibodies); 0 (Ribonucleoproteins); 0 (SS-A antibodies)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171006
[Lr] Data última revisão:
171006
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170929
[St] Status:MEDLINE
[do] DOI:10.1093/rheumatology/kex263


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[PMID]:28923901
[Au] Autor:Stohl HE; Lee RH; Manetta J; Kikly K; Korst LM; Stohl W
[Ad] Endereço:From the Department of Obstetrics and Gynecology, Harbor-UCLA Medical Center, David Geffen School of Medicine at UCLA, Los Angeles, CA (H.E.S.); Department of Obstetrics and Gynecology (R.H.L.) and Division of Rheumatology, Department of Medicine (W.S.), Los Angeles County+University of Southern Cal
[Ti] Título:Maternal Serum B-Cell Activating Factor Levels: Candidate Early Biomarker for Hypertensive Disorders of Pregnancy.
[So] Source:Hypertension;70(5):1007-1013, 2017 Nov.
[Is] ISSN:1524-4563
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Hypertensive disorders of pregnancy are a leading cause of maternal and perinatal morbidity and mortality. Early suppression of B-cell lymphopoiesis is necessary for a normal pregnancy. Dysregulation of factors critical to B-cell survival may result in pregnancy complications, including hypertension. In this prospective observational study at a single medical center, serum levels of BAFF (B-cell activating factor) were measured in pregnant participants at each trimester, at delivery, and postpartum and in nonpregnant controls at a single time point. Comparisons were made between nonpregnant and pregnant subjects and between time periods of pregnancy. First-trimester serum BAFF levels were further tested for association with hypertensive disorders of pregnancy. The study included 149 healthy pregnant women, 25 pregnant women with chronic hypertension, and 48 nonpregnant controls. Median first-trimester serum BAFF level (ng/mL) for healthy women (0.90) was lower than median serum BAFF levels for women with chronic hypertension (0.96; =0.013) and controls (1.00; =0.002). Serum BAFF levels steadily declined throughout pregnancy, with the median second-trimester level lower than the corresponding first-trimester level (0.77; =0.003) and the median third-trimester level lower than the corresponding second-trimester level (0.72; =0.025). The median first-trimester serum BAFF level was elevated in women who subsequently developed hypertension compared with women who remained normotensive (1.02 versus 0.85; =0.012), with the area under the receiver operating characteristic curve being 0.709. First-trimester serum BAFF level may be an early and clinically useful predictor of hypertensive disorders of pregnancy.
[Mh] Termos MeSH primário: Fator Ativador de Células B/sangue
Hipertensão
Complicações Cardiovasculares na Gravidez
Trimestres da Gravidez/sangue
[Mh] Termos MeSH secundário: Adulto
Linfócitos B/fisiologia
California/epidemiologia
Diagnóstico Precoce
Feminino
Seres Humanos
Hipertensão/sangue
Hipertensão/diagnóstico
Hipertensão/epidemiologia
Linfopoese/fisiologia
Valor Preditivo dos Testes
Gravidez
Complicações Cardiovasculares na Gravidez/sangue
Complicações Cardiovasculares na Gravidez/diagnóstico
Curva ROC
Estatística como Assunto
[Pt] Tipo de publicação:JOURNAL ARTICLE; OBSERVATIONAL STUDY
[Nm] Nome de substância:
0 (B-Cell Activating Factor)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171020
[Lr] Data última revisão:
171020
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170920
[St] Status:MEDLINE
[do] DOI:10.1161/HYPERTENSIONAHA.117.09775


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[PMID]:28893900
[Au] Autor:Webster LM; Myers JE; Nelson-Piercy C; Harding K; Cruickshank JK; Watt-Coote I; Khalil A; Wiesender C; Seed PT; Chappell LC
[Ad] Endereço:From the Women's Health Academic Centre, King's College London, United Kingdom (L.M.W., C.N.-P., P.T.S., L.C.C.); Directorate of Women's Health, Guy's and St Thomas' Foundation Trust, London, United Kingdom (L.M.W., C.N.-P., K.H., L.C.C.); Maternaland Fetal Health ResearchCenter, Division of Develop
[Ti] Título:Labetalol Versus Nifedipine as Antihypertensive Treatment for Chronic Hypertension in Pregnancy: A Randomized Controlled Trial.
[So] Source:Hypertension;70(5):915-922, 2017 Nov.
[Is] ISSN:1524-4563
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Data from randomized controlled trials to guide antihypertensive agent choice for chronic hypertension in pregnancy are limited; this study aimed to compare labetalol and nifedipine, additionally assessing the impact of ethnicity on treatment efficacy. Pregnant women with chronic hypertension (12 -27 weeks' gestation) were enrolled at 4 UK centers (August 2014 to October 2015). Open-label first-line antihypertensive treatment was randomly assigned: labetalol- (200-1800 mg/d) or nifedipine-modified release (20-80 mg/d). Analysis included 112 women (98%) who completed the study (labetalol n=55, nifedipine n=57). Maximum blood pressure after randomization was 161/101 mm Hg with labetalol versus 163/105 mm Hg with nifedipine (mean difference systolic: 1.2 mm Hg [-4.9 to 7.2 mm Hg], diastolic: 3.3 mm Hg [-0.6 to 7.3 mm Hg]). Mean blood pressure was 134/84 mm Hg with labetalol and 134/85 mm Hg with nifedipine (mean difference systolic: 0.3 mm Hg [-2.8 to 3.4 mm Hg], and diastolic: -1.9 mm Hg [-4.1 to 0.3 mm Hg]). Nifedipine use was associated with a 7.4-mm Hg reduction (-14.4 to -0.4 mm Hg) in central aortic pressure, measured by pulse wave analysis. No difference in treatment effect was observed in black women (n=63), but a mean 4 mm Hg reduction (-6.6 to -0.8 mm Hg; =0.015) in brachial diastolic blood pressure was observed with labetalol compared with nifedipine in non-black women (n=49). Labetalol and nifedipine control mean blood pressure to target in pregnant women with chronic hypertension. This study provides support for a larger definitive trial scrutinizing the benefits and side effects of first-line antihypertensive treatment. CLINICAL TRIAL REGISTRATION: URL: https://www.isrctn.com. Unique identifier: ISRCTN40973936.
[Mh] Termos MeSH primário: Pressão Arterial/efeitos dos fármacos
Hipertensão
Labetalol
Nifedipino
Complicações Cardiovasculares na Gravidez
[Mh] Termos MeSH secundário: Adulto
Anti-Hipertensivos/administração & dosagem
Anti-Hipertensivos/efeitos adversos
Determinação da Pressão Arterial/métodos
Monitoramento de Medicamentos/métodos
Feminino
Idade Gestacional
Seres Humanos
Hipertensão/diagnóstico
Hipertensão/tratamento farmacológico
Labetalol/administração & dosagem
Labetalol/efeitos adversos
Nifedipino/administração & dosagem
Nifedipino/efeitos adversos
Gravidez
Complicações Cardiovasculares na Gravidez/diagnóstico
Complicações Cardiovasculares na Gravidez/tratamento farmacológico
Análise de Onda de Pulso/métodos
Resultado do Tratamento
Reino Unido
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (Antihypertensive Agents); I9ZF7L6G2L (Nifedipine); R5H8897N95 (Labetalol)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171020
[Lr] Data última revisão:
171020
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170913
[St] Status:MEDLINE
[do] DOI:10.1161/HYPERTENSIONAHA.117.09972


  10 / 14919 MEDLINE  
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[PMID]:28893895
[Au] Autor:Tooher J; Thornton C; Makris A; Ogle R; Korda A; Hennessy A
[Ad] Endereço:From the Western Sydney University, School of Medicine, Australia (J.T., C.T., A.M., A.K., A.H.); Royal Prince Alfred Hospital, Sydney, Australia (J.T., R.O., A.K.); and Renal Department, Liverpool Hospital, Sydney, Australia (A.M.). Jane.Tooher@sswahs.nsw.gov.au.
[Ti] Título:All Hypertensive Disorders of Pregnancy Increase the Risk of Future Cardiovascular Disease.
[So] Source:Hypertension;70(4):798-803, 2017 Oct.
[Is] ISSN:1524-4563
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Hypertensive disorders of pregnancy are associated with vascular dysfunction in the pregnancy and an increased risk of long-term cardiovascular disease (CVD) in the mother. What remains to be understood is whether the length, severity of the disease, the treatment of hypertension in pregnancy, or the subtype of hypertensive disorders of pregnancy are significant predictors of future CVD. We undertook a retrospective cohort study to review all women who gave birth at a tertiary hospital in Sydney between the years 1980 and 1989 (n=31 656). A cohort of women was further defined by having hypertension during the antenatal, intrapartum, or postnatal periods (n=4387). Randomly selected records of women (n=1158) with a hypertensive disorder of pregnancy were individually reviewed to collect data on their pregnancy and pregnancy outcomes. The entire cohort then underwent linkage analysis to future CVDs. Women who presented with gestational hypertension were at greater risk of future hypertension and ischemic heart disease compared with the women who were diagnosed with preeclampsia. There was no significant difference between the women who were treated with antihypertensive medication and the women who did not receive antihypertensive medication or the duration of hypertensive disorders of pregnancy and future admission for CVD, although severity of hypertension tracked with increased risk of future hypertension in all groups. This study demonstrated that all women who present with any of the subtypes of hypertensive disorders in pregnancy are at significant risk of future CVD compared with women who remain normotensive during their pregnancy.
[Mh] Termos MeSH primário: Anti-Hipertensivos/uso terapêutico
Doenças Cardiovasculares/epidemiologia
Hipertensão
[Mh] Termos MeSH secundário: Adulto
Austrália/epidemiologia
Feminino
Seres Humanos
Hipertensão/classificação
Hipertensão/diagnóstico
Hipertensão/epidemiologia
Hipertensão/terapia
Registros Médicos Orientados a Problemas/estatística & dados numéricos
Gravidez
Complicações Cardiovasculares na Gravidez/classificação
Complicações Cardiovasculares na Gravidez/diagnóstico
Complicações Cardiovasculares na Gravidez/epidemiologia
Complicações Cardiovasculares na Gravidez/terapia
Resultado da Gravidez/epidemiologia
Prognóstico
Distribuição Aleatória
Estudos Retrospectivos
Fatores de Risco
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antihypertensive Agents)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170928
[Lr] Data última revisão:
170928
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170913
[St] Status:MEDLINE
[do] DOI:10.1161/HYPERTENSIONAHA.117.09246



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