Base de dados : MEDLINE
Pesquisa : C14.280.067.558.230 [Categoria DeCS]
Referências encontradas : 1821 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 183 ir para página                         

  1 / 1821 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29419690
[Au] Autor:Xing F; Jiang J; Hu X; Feng C; He J; Dong Y; Ma Y; Tang A
[Ad] Endereço:Department of Cardiology, The First Affiliated Hospital of Sun Yat-Sen University.
[Ti] Título:Association between paced QRS duration and atrial fibrillation after permanent pacemaker implantation: A retrospective observational cohort study.
[So] Source:Medicine (Baltimore);97(6):e9839, 2018 Feb.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Right ventricular pacing often results in prolonged QRS duration (QRSd) as the result of right ventricular stimulation, and atrial fibrillation (AF) may result. The association of pacing-induced prolonged QRSd and AF in patients with permanent pacemakers is unknown.We selected 180 consecutive patients who underwent pacemaker implantation for complete/advanced atrioventricular block. All of the patients were paced from the right ventricular septum. Electrocardiography recordings were obtained at the beginning and the end of pacemaker implantation. QRSd was measured in all 12 leads. The QRSd variation was calculated by subtracting the preimplantation QRSd from the postimplantation QRSd.The occurrence of AF was observed in 64 (35.56%) patients (follow-up 33.62 ±â€Š21.47 mo). No significant differences in preimplantation QRSd were observed between the AF occurrence and nonoccurrence groups. The QRSd variation in leads V4 (54.22 ±â€Š29.03 vs 42.66 ±â€Š33.79 ms, P = .022), and V6 (64.62 ±â€Š23.16 vs 48.45 ±â€Š34.40 ms, P = .001) differed significantly between the occurrence and nonoccurrence groups. More QRSd variation in lead V6 (P = .005, HR = 1.822, 95% CI 1.174-2.718, interval scale of QRSd was 40 ms) and left atrial diameter (P = .045, HR = 1.042, 95% CI 1.001-1.086) were independent risk factors for AF occurrence. Receiver operating characteristic curve suggested that QRSd variation in lead V6 could predict AF occurrence, especially for patients with long preimplantation QRSd (≥120 ms, area under the curve was 0.826, 95% CI 0.685-0.967).QRSd variation in lead V6 might be positively correlated with postimplantation AF occurrence. In patients with pacemaker implantation, QRSd could be a complementary criterion for optimizing the right ventricular septal pacing site, and smallest QRSd might be worth pursuing.
[Mh] Termos MeSH primário: Fibrilação Atrial
Bloqueio Atrioventricular
Eletrocardiografia/métodos
Átrios do Coração/patologia
Marca-Passo Artificial/efeitos adversos
[Mh] Termos MeSH secundário: Idoso
Fibrilação Atrial/diagnóstico
Fibrilação Atrial/epidemiologia
Fibrilação Atrial/etiologia
Bloqueio Atrioventricular/diagnóstico
Bloqueio Atrioventricular/terapia
China/epidemiologia
Feminino
Seres Humanos
Masculino
Meia-Idade
Tamanho do Órgão
Avaliação de Resultados (Cuidados de Saúde)
Fatores de Risco
[Pt] Tipo de publicação:JOURNAL ARTICLE; OBSERVATIONAL STUDY
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180214
[Lr] Data última revisão:
180214
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180209
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000009839


  2 / 1821 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29208037
[Au] Autor:Posthumus L; Donker ME
[Ad] Endereço:Spaarne Gasthuis, Spaarnepoort 1, 2134 TM, Hoofddorp, The Netherlands.
[Ti] Título:Uterine rupture in a primigravid patient, an uncommon but severe obstetrical event: a case report.
[So] Source:J Med Case Rep;11(1):339, 2017 Dec 06.
[Is] ISSN:1752-1947
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: A spontaneous rupture of the unscarred uterus in a primigravid patient is extremely rare and is associated with high perinatal and maternal morbidity and mortality. CASE PRESENTATION: A 34-year-old white primigravid woman, 31 + 3 weeks of gestation, presented with pre-eclampsia and developed a sudden acute abdomen. An emergency laparotomy was performed and a uterine rupture was found as the cause of the event. A stillborn girl was born. CONCLUSION: A rupture of the pregnant uterus should always be considered in a pregnant woman presenting with abdominal pain, even in a primigravid patient.
[Mh] Termos MeSH primário: Número de Gestações
Natimorto
Ruptura Uterina/cirurgia
[Mh] Termos MeSH secundário: Dor Abdominal/etiologia
Adulto
Antibacterianos/uso terapêutico
Bloqueio Atrioventricular
Bacteriemia/tratamento farmacológico
Eletrocardiografia
Feminino
Seres Humanos
Laparotomia
Complicações Pós-Operatórias/tratamento farmacológico
Gravidez
Terceiro Trimestre da Gravidez
Infecções Estafilocócicas/tratamento farmacológico
Staphylococcus aureus
Ruptura Uterina/diagnóstico
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Bacterial Agents)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180130
[Lr] Data última revisão:
180130
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171207
[St] Status:MEDLINE
[do] DOI:10.1186/s13256-017-1507-9


  3 / 1821 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Registro de Ensaios Clínicos
Texto completo
[PMID]:28450351
[Au] Autor:Flyer JN; Zuckerman WA; Richmond ME; Anderson BR; Mendelsberg TG; McAllister JM; Liberman L; Addonizio LJ; Silver ES
[Ad] Endereço:From Division of Pediatric Cardiology, Columbia University Medical Center, New York, NY.
[Ti] Título:Prospective Study of Adenosine on Atrioventricular Nodal Conduction in Pediatric and Young Adult Patients After Heart Transplantation.
[So] Source:Circulation;135(25):2485-2493, 2017 Jun 20.
[Is] ISSN:1524-4539
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Supraventricular tachycardia is common after heart transplantation. Adenosine, the standard therapy for treating supraventricular tachycardia in children and adults without transplantation, is relatively contraindicated after transplantation because of a presumed risk of prolonged atrioventricular block in denervated hearts. This study tested whether adenosine caused prolonged asystole after transplantation and if it was effective in blocking atrioventricular nodal conduction in these patients. METHODS: This was a single-center prospective clinical study including healthy heart transplant recipients 6 months to 25 years of age presenting for routine cardiac catheterization during 2015 to 2016. After catheterization, a transvenous pacing catheter was placed and adenosine was given following a dose-escalation protocol until atrioventricular block was achieved. The incidence of clinically significant asystole (≥12 seconds after adenosine) was quantified. The effects of patient characteristics on adenosine dose required to produce atrioventricular block and duration of effect were also measured. RESULTS: Eighty patients completed adenosine testing. No patient (0%; 95% confidence interval, 0-3) required rescue ventricular pacing. Atrioventricular block was observed in 77 patients (96%; 95% confidence interval, 89-99). The median longest atrioventricular block was 1.9 seconds (interquartile range, 1.4-3.2 seconds), with a mean duration of adenosine effect of 4.3±2.0 seconds. No patient characteristic significantly predicted the adenosine dose to produce atrioventricular block or duration of effect. Results were similar across patient weight categories. CONCLUSIONS: Adenosine induces atrioventricular block in healthy pediatric and young adult heart transplant recipients with minimal risk when low initial doses are used (25 µg/kg; 1.5 mg if ≥60 kg) and therapy is gradually escalated. CLINICAL TRIAL REGISTRATION: URL: http://www.clinicaltrials.gov. Unique identifier: NCT02462941.
[Mh] Termos MeSH primário: Adenosina/administração & dosagem
Bloqueio Atrioventricular/fisiopatologia
Nó Atrioventricular/fisiologia
Sistema de Condução Cardíaco/fisiologia
Transplante de Coração/tendências
[Mh] Termos MeSH secundário: Administração Intravenosa
Adolescente
Antiarrítmicos/administração & dosagem
Bloqueio Atrioventricular/induzido quimicamente
Nó Atrioventricular/efeitos dos fármacos
Criança
Pré-Escolar
Relação Dose-Resposta a Droga
Feminino
Sistema de Condução Cardíaco/diagnóstico por imagem
Seres Humanos
Lactente
Masculino
Estudos Prospectivos
Adulto Jovem
[Pt] Tipo de publicação:CLINICAL TRIAL; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Arrhythmia Agents); K72T3FS567 (Adenosine)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:180121
[Lr] Data última revisão:
180121
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170429
[Cl] Clinical Trial:ClinicalTrial
[St] Status:MEDLINE
[do] DOI:10.1161/CIRCULATIONAHA.117.028087


  4 / 1821 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29095320
[Au] Autor:Wang HT; Liu WH; Chen YL
[Ad] Endereço:aEmergency Department bDivision of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
[Ti] Título:Transient sick sinus syndrome with complete atrioventricular block associated with ergonovine intake: A case report.
[So] Source:Medicine (Baltimore);96(44):e8559, 2017 Nov.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:RATIONALE: More mature or older women are more likely to undergo in vitro fertilization and embryo implant. These women have a greater chance of receiving ergonovine therapy because of a suspected abortion. We present this case report to call attention to a latent lethal adverse effect in everyday obstetric practice using ergonovine. It requires more attention and close monitoring PATIENT CONCERNS:: We presented the case of a 38-year-old female patient with general weakness and mild chest tightness after ergonovine use. DIAGNOSES: She was diagnosed as transient sick sinus syndrome and complete atrioventricular block with junctional escape rhythm after diagnostic work up. INTERVENTIONS: Conservative treatment with discontinuation of ergonovine and bed rest. OUTCOMES: Her sinus rhythm returned to normal the day after ergonovine was discontinued. The patient remained symptom-free since recovery of her sinus rhythm. LESSONS: Ergonovine may cause symptomatic and lethal bradyarrhythmia. Withdrawal of the causative medication and adequate supportive care can lead to a favorable outcome in these patients. More related cases should be reported. Further evaluation for treatment and prognosis are necessary.
[Mh] Termos MeSH primário: Bloqueio Atrioventricular/induzido quimicamente
Ergonovina/efeitos adversos
Ocitócicos/efeitos adversos
Síndrome do Nó Sinusal/induzido quimicamente
[Mh] Termos MeSH secundário: Adulto
Bloqueio Atrioventricular/terapia
Repouso em Cama
Tratamento Conservador/métodos
Feminino
Seres Humanos
Síndrome do Nó Sinusal/terapia
Resultado do Tratamento
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Oxytocics); WH41D8433D (Ergonovine)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171109
[Lr] Data última revisão:
171109
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171103
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000008559


  5 / 1821 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28957562
[Au] Autor:Sonesson SE; Hedlund M; Ambrosi A; Wahren-Herlenius M
[Ad] Endereço:Pediatric Cardiology Unit, Department of Women's and Children's Health.
[Ti] Título:Factors influencing fetal cardiac conduction in anti-Ro/SSA-positive pregnancies.
[So] Source:Rheumatology (Oxford);56(10):1755-1762, 2017 Oct 01.
[Is] ISSN:1462-0332
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Objectives: Congenital heart block (CHB) develops in 1-2% of anti-Ro/SSA-positive pregnancies and has a recurrence rate of 12-20%, which indicates that factors other than maternal autoantibodies are crucial for CHB to occur. Here, we aimed to evaluate the influence of factors previously associated with CHB on the occurrence of milder forms of fetal cardiac conduction disturbances, shown to occur in up to 30% of anti-Ro/SSA-positive pregnancies, and on neonatal outcome in a large cohort of prospectively followed pregnancies. Methods: The association of maternal age, season of the year and history of atrioventricular block (AVB) with the development of fetal Doppler and neonatal ECG conduction disturbances was evaluated in 212 anti-Ro52/SSA-positive singleton pregnancies. Results: Maternal age was significantly higher in AVB II-III pregnancies but was not correlated with fetal AV time intervals in fetuses without signs of AVB II-III. AV time intervals of fetuses surveilled during the winter were significantly longer than those of fetuses surveilled during the summer. Fetal AV time intervals in consecutive pregnancies from the same women were significantly correlated. A history of AVB II-III was associated with significantly longer AV time intervals, and AVB I-III was observed at birth in 38% of babies born after a sibling with abnormal fetal AV conduction. Conclusion: Our study shows that AV time intervals in anti-Ro/SSA antibody-exposed fetuses during the CHB risk period are influenced by the season of the year, and reveals that the recurrence of conduction disturbances in antibody-exposed fetuses is higher than previously reported when milder forms are taken into account.
[Mh] Termos MeSH primário: Anticorpos Antinucleares
Bloqueio Atrioventricular/fisiopatologia
Coração Fetal/fisiopatologia
Bloqueio Cardíaco/congênito
Complicações Cardiovasculares na Gravidez/imunologia
Estações do Ano
[Mh] Termos MeSH secundário: Adulto
Anticorpos Antinucleares/sangue
Bloqueio Atrioventricular/congênito
Autoanticorpos/sangue
Ecocardiografia Doppler/métodos
Feminino
Coração Fetal/diagnóstico por imagem
Bloqueio Cardíaco/diagnóstico por imagem
Bloqueio Cardíaco/fisiopatologia
Seres Humanos
Gravidez
Complicações Cardiovasculares na Gravidez/sangue
Complicações Cardiovasculares na Gravidez/diagnóstico por imagem
Resultado da Gravidez
Estudos Prospectivos
Ribonucleoproteínas/imunologia
Fatores de Risco
Ultrassonografia Pré-Natal/métodos
[Pt] Tipo de publicação:EVALUATION STUDIES; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antibodies, Antinuclear); 0 (Autoantibodies); 0 (Ribonucleoproteins); 0 (SS-A antibodies)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171006
[Lr] Data última revisão:
171006
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170929
[St] Status:MEDLINE
[do] DOI:10.1093/rheumatology/kex263


  6 / 1821 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28938964
[Au] Autor:Keßler M; Gonska B; Seeger J; Rottbauer W; Wöhrle J
[Ad] Endereço:Department of Internal Medicine II, University of Ulm, Ulm, Germany.
[Ti] Título:Predictors of permanent pacemaker implantation after transfemoral aortic valve implantation with the Lotus valve.
[So] Source:Am Heart J;192:57-63, 2017 Oct.
[Is] ISSN:1097-6744
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Permanent pacemaker implantation (PPMI) after transcatheter aortic valve implantation is of high clinical relevance, but PPMI rates differ widely between valve types. Although the Lotus valve can be repositioned, reported rates for PPMI are high. The predictors of PPMI after Lotus valve implantation have not been defined yet. METHODS: We analyzed the impact of preexisting conduction disturbances, depth of implantation, oversizing, and amount of calcification on PPMI in 216 patients with severe symptomatic aortic stenosis underdoing Lotus valve implantation. RESULTS: PPMI was required in 39.8% of patients. Patients with need for PPMI compared with patients without need for PPMI had more often the following criteria: male gender (P=.035); preprocedural right bundle-branch block (RBBB) (16.3% vs 0, P<.001); atrioventricular (AV) block first degree (26.7% vs 10.1%, P=.004); higher calcium volume of the left coronary cusp (63.1±87.5 mm vs 42.8±49.3 mm , P=.05); and deeper valve implantation at right coronary (P=.011), noncoronary (P=.026), and left coronary (P=.012) position. Oversizing in relation to annulus and left ventricular outflow tract did not have an impact on need for PPMI. By multiple regression analysis, preprocedural AV block first degree (P=.005), RBBB (P<.001), and depth of implantation (P=.006) were independent risk factors for need of PPMI. CONCLUSIONS: In patients with severe aortic stenosis receiving transfemoral Lotus valve, preexisting AV block first degree, RBBB, and implantation depth are independent predictors of PPMI, highlighting the importance of careful valve positioning.
[Mh] Termos MeSH primário: Estenose da Valva Aórtica/cirurgia
Valva Aórtica/cirurgia
Bloqueio Atrioventricular/terapia
Sistema de Condução Cardíaco/fisiopatologia
Próteses Valvulares Cardíacas
Marca-Passo Artificial
Substituição da Valva Aórtica Transcateter/efeitos adversos
[Mh] Termos MeSH secundário: Idoso de 80 Anos ou mais
Estenose da Valva Aórtica/complicações
Estenose da Valva Aórtica/diagnóstico
Bloqueio Atrioventricular/complicações
Bloqueio Atrioventricular/diagnóstico
Cateterismo Cardíaco
Ecocardiografia
Eletrocardiografia
Feminino
Seguimentos
Seres Humanos
Masculino
Desenho de Prótese
Estudos Retrospectivos
Fatores de Risco
Tomografia Computadorizada por Raios X
Resultado do Tratamento
[Pt] Tipo de publicação:CLINICAL TRIAL; JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170929
[Lr] Data última revisão:
170929
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170924
[St] Status:MEDLINE


  7 / 1821 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28864321
[Au] Autor:Socie P; Nicot F; Baudinaud P; Estagnasie P; Brusset A; Squara P; Nguyen LS
[Ad] Endereço:Critical Care Medicine Department, CMC Ambroise Paré, Neuilly-sur-Seine, France.
[Ti] Título:Frequency of Recovery from Complete Atrioventricular Block After Cardiac Surgery.
[So] Source:Am J Cardiol;120(10):1841-1846, 2017 Nov 15.
[Is] ISSN:1879-1913
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Best timing for permanent pacemaker implantation to treat complete atrioventricular block (AVB) after cardiac surgery is unclear, as late pacemaker dependency was found low in recent observational studies. This study aimed to identify factors associated with spontaneous recovery from AVB. In a prospective and observational cohort, all patients who underwent cardiothoracic surgery during a 14-month-period were included (n = 1,200). Risk factors of postoperative AVB were assessed by logistic regression. Among patients who developed AVB, variables associated with recovery from AVB were assessed by Cox and logistic regression. Overall incidence of postoperative AVB was 6.0%. Risk factors of AVB were age (OR 1.03 [1.00 to 1.06], p = 0.023); female gender (OR 2.06 [1.24 to 3.41], p = 0.005), active endocarditis (OR 3.31 [1.33 to 8.26], p = 0.01), and aortic valve replacement (OR 3.17 [1.92 to 5.25], p <0.001). Among aortic valve replacement, sutureless aortic valve replacement was associated with more AVB (26.7% vs 8.1%, p <0.01). Recovery from AVB occurred in 30 patients (41.7%) in a median period of 3 days [interquartile range = 1;5]. Among patients who would recover from AVB, 90% of patients did so before day 7. None of the studied variable was independently associated with recovery from AVB. In conclusion, identified risk factors of postoperative AVB after cardiac surgery were age, female gender, endocarditis, and aortic valve replacement. Because most patients who would recover did so before day 7, this study validates modern guidelines suggesting permanent pacemaker implantation on day 7.
[Mh] Termos MeSH primário: Bloqueio Atrioventricular/fisiopatologia
Procedimentos Cirúrgicos Cardíacos/efeitos adversos
Eletrocardiografia
Sistema de Condução Cardíaco/fisiologia
Complicações Pós-Operatórias
Recuperação de Função Fisiológica
[Mh] Termos MeSH secundário: Idoso
Bloqueio Atrioventricular/epidemiologia
Feminino
Seguimentos
França/epidemiologia
Seres Humanos
Incidência
Masculino
Prognóstico
Estudos Prospectivos
Remissão Espontânea
Fatores de Risco
Fatores de Tempo
[Pt] Tipo de publicação:JOURNAL ARTICLE; OBSERVATIONAL STUDY
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171102
[Lr] Data última revisão:
171102
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170903
[St] Status:MEDLINE


  8 / 1821 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28734433
[Au] Autor:Maseda Uriza R; Jurado-Román A; Jimenez Díaz J; Piqueras Flores J; Higuera Sobrino F; Oliva De Anquín E
[Ad] Endereço:Cardiology Department, University General Hospital, Ciudad Real, Spain. Electronic address: maseda12@hotmail.com.
[Ti] Título:Hybrid Approach for the Treatment of Superior Vena Cava Syndrome Induced by Pacemaker.
[So] Source:Ann Thorac Surg;104(2):e131-e132, 2017 Aug.
[Is] ISSN:1552-6259
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Pacemaker-induced superior vena cava syndrome (SVCS) is a rare but incapacitating adverse event that can occur years after implantation. Inasmuch as it is a rare disease, there is no consensus about its treatment. The most widely used option is balloon angioplasty and venous stent implantation, with preservation of the lead or previous extraction and subsequent reimplantation after the procedure, which is associated with new episodes of thrombosis. The epicardial implantation reduces the risk of thrombosis. We report a case of pacemaker-induced SVCS for which we used a hybrid approach for epicardial lead implantation and electrode extraction, balloon angioplasty, and stent implantation.
[Mh] Termos MeSH primário: Bloqueio Atrioventricular/terapia
Cateterismo Periférico/métodos
Remoção de Dispositivo/métodos
Marca-Passo Artificial/efeitos adversos
Síndrome da Veia Cava Superior/cirurgia
Toracotomia/métodos
[Mh] Termos MeSH secundário: Idoso
Veia Femoral
Seres Humanos
Masculino
Flebografia
Síndrome da Veia Cava Superior/diagnóstico
Síndrome da Veia Cava Superior/etiologia
Tomografia Computadorizada por Raios X
Ultrassonografia Doppler
Veia Cava Superior/diagnóstico por imagem
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170906
[Lr] Data última revisão:
170906
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170724
[St] Status:MEDLINE


  9 / 1821 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28712476
[Au] Autor:Muzhikov V; Vershinina E; Belenky V; Muzhikov R
[Ad] Endereço:Med Byte Limited, Saint Petersburg, Russia. Electronic address: mujikov_v@mail.ru.
[Ti] Título:Comparative Assessment of the Heart's Functioning by Using the Akabane Test and Classical Methods of Instrumental Examination.
[So] Source:J Acupunct Meridian Stud;10(3):171-179, 2017 Jun.
[Is] ISSN:2093-8152
[Cp] País de publicação:Korea (South)
[La] Idioma:eng
[Ab] Resumo:Acupuncture physicians have studied the application of reflexotherapy to cardiology. However, no one has investigated the connection of ancient Chinese diagnostic methods with modern tools. A total of 102 patients (54 men and 48 women) with heart pathology, namely, sick-sinus syndrome, Wolff-Parkinson-White syndrome, and atrioventricular blockade, were studied using the usual instrumental methods (transesophageal electrophysiological study of the heart, echocardiography), after which they underwent Akabane thermopuncture testing as in traditional Chinese medicine. The results of cardio examination from one side of the Akabane test with that from the other side were compared by means of a multiple stepwise regression analysis. We revealed the effects on the characteristic pattern of acupuncture channel lesions inherent in a definite heart pathology, i.e., the most vulnerable acupuncture channel (AC), of such factors as disturbances of the contractile, conductive, or automatic heart functions, and changes in the chambers' size or circulation volume. Сhanges in the indices of the left and the right branches of these channels usually reflect the opposing natures of the changes in these indicators, which should be considered in reflexotherapy. The main value of the Akabane test along with the use of mathematical analysis lies in early, quick, and inexpensive detection of the above-mentioned heart disturbances.
[Mh] Termos MeSH primário: Bloqueio Atrioventricular/diagnóstico
Coração/fisiopatologia
Síndrome do Nó Sinusal/diagnóstico
Síndrome de Wolff-Parkinson-White/diagnóstico
[Mh] Termos MeSH secundário: Acupuntura/métodos
Ecocardiografia/métodos
Feminino
Coração/diagnóstico por imagem
Sistema de Condução Cardíaco/fisiopatologia
Seres Humanos
Hipertermia Induzida/métodos
Masculino
Meridianos
Reflexoterapia/métodos
Síndrome do Nó Sinusal/diagnóstico por imagem
Síndrome do Nó Sinusal/fisiopatologia
Nó Sinoatrial/fisiopatologia
Síndrome de Wolff-Parkinson-White/diagnóstico por imagem
Síndrome de Wolff-Parkinson-White/fisiopatologia
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170830
[Lr] Data última revisão:
170830
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170718
[St] Status:MEDLINE


  10 / 1821 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28705318
[Au] Autor:Seki A; Ishikawa T; Daumy X; Mishima H; Barc J; Sasaki R; Nishii K; Saito K; Urano M; Ohno S; Otsuki S; Kimoto H; Baruteau AE; Thollet A; Fouchard S; Bonnaud S; Parent P; Shibata Y; Perrin JP; Le Marec H; Hagiwara N; Mercier S; Horie M; Probst V; Yoshiura KI; Redon R; Schott JJ; Makita N
[Ad] Endereço:Department of Cardiology, Tokyo Women's Medical University, Tokyo, Japan; Support Center for Women Health Care Professionals and Researchers, Tokyo Women's Medical University, Tokyo, Japan.
[Ti] Título:Progressive Atrial Conduction Defects Associated With Bone Malformation Caused by a Connexin-45 Mutation.
[So] Source:J Am Coll Cardiol;70(3):358-370, 2017 Jul 18.
[Is] ISSN:1558-3597
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Inherited cardiac conduction disease is a rare bradyarrhythmia associated with mutations in various genes that affect action potential propagation. It is often characterized by isolated conduction disturbance of the His-Purkinje system, but it is rarely described as a syndromic form. OBJECTIVES: The authors sought to identify the genetic defect in families with a novel bradyarrhythmia syndrome associated with bone malformation. METHODS: The authors genetically screened 15 European cases with genotype-negative de novo atrioventricular (AV) block and their parents by trio whole-exome sequencing, plus 31 Japanese cases with genotype-negative familial AV block or sick sinus syndrome by targeted exon sequencing of 457 susceptibility genes. Functional consequences of the mutation were evaluated using an in vitro cell expression system and in vivo knockout mice. RESULTS: The authors identified a connexin-45 (Cx45) mutation (p.R75H) in 2 unrelated families (a de novo French case and a 3-generation Japanese family) who presented with progressive AV block, which resulted in atrial standstill without ventricular conduction abnormalities. Affected individuals shared a common extracardiac phenotype: a brachyfacial pattern, finger deformity, and dental dysplasia. Mutant Cx45 expressed in Neuro-2a cells showed normal hemichannel assembly and plaque formation. However, Lucifer yellow dye transfer and gap junction conductance between cell pairs were severely impaired, which suggested that mutant Cx45 impedes gap junction communication in a dominant-negative manner. Tamoxifen-induced, cardiac-specific Cx45 knockout mice showed sinus node dysfunction and atrial arrhythmia, recapitulating the intra-atrial disturbance. CONCLUSIONS: Altogether, the authors showed that Cx45 mutant p.R75H is responsible for a novel disease entity of progressive atrial conduction system defects associated with craniofacial and dentodigital malformation.
[Mh] Termos MeSH primário: Bloqueio Atrioventricular/etiologia
Conexinas/genética
DNA/genética
Deformidades Dentofaciais/complicações
Mutação
[Mh] Termos MeSH secundário: Adolescente
Adulto
Animais
Bloqueio Atrioventricular/genética
Bloqueio Atrioventricular/fisiopatologia
Criança
Pré-Escolar
Conexinas/metabolismo
Análise Mutacional de DNA
Deformidades Dentofaciais/genética
Deformidades Dentofaciais/metabolismo
Modelos Animais de Doenças
Progressão da Doença
Eletrocardiografia
Feminino
Seres Humanos
Masculino
Camundongos
Camundongos Transgênicos
Meia-Idade
Linhagem
Fenótipo
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Connexins); 0 (connexin 45); 9007-49-2 (DNA)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170901
[Lr] Data última revisão:
170901
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170715
[St] Status:MEDLINE



página 1 de 183 ir para página                         
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde