[PMID]: | 28126025 |
[Au] Autor: | Marsh KM; Ferng AS; Pilikian T; Desai AA; Avery R; Friedman M; Oliva I; Jokerst C; Schipper D; Khalpey Z |
[Ad] Endereço: | Department of Surgery, Division of Cardiothoracic Surgery, University of Arizona College of Medicine, 1501 North Campbell Avenue, Room 4302, Tucson, AZ, 85724, USA. |
[Ti] Título: | Anti-inflammatory properties of amniotic membrane patch following pericardiectomy for constrictive pericarditis. |
[So] Source: | J Cardiothorac Surg;12(1):6, 2017 Jan 26. |
[Is] ISSN: | 1749-8090 |
[Cp] País de publicação: | England |
[La] Idioma: | eng |
[Ab] Resumo: | BACKGROUND: Since constrictive pericarditis is most often idiopathic and the pathophysiology remains largely unknown, both the diagnosis and the treatment can be challenging. However, by definition, inflammatory processes are central to this disease process. Amniotic membrane patches have been shown to possess anti-inflammatory properties and are believed to be immune privileged. Due to these properties, amniotic membrane patches were applied intraoperatively in a complicated patient presenting with constrictive pericarditis. CASE PRESENTATION: A patient with a history of multiple cardiac surgeries presented with marked fatigue, worsening dyspnea and sinus tachycardia. He was found to have constrictive physiology during cardiac catheterization, with cardiac MRI demonstrating hepatic vein dilatation, atrial enlargement and ventricular narrowing. After amniotic membrane patch treatment and pericardiectomy, post-operative cardiac MRI failed to demonstrate any appreciable pericardial effusion or inflammation, with no increased T2 signal that would suggest edema. CONCLUSIONS: Given the positive results seen in this complex patient, we suggest continued research into the beneficial properties of amniotic membrane patches in cardiac surgery. |
[Mh] Termos MeSH primário: |
Âmnio/transplante Inflamação/terapia Pericardiectomia Pericardite Constritiva/cirurgia
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[Mh] Termos MeSH secundário: |
Adulto Âmnio/fisiologia Seres Humanos Imagem por Ressonância Magnética Masculino Derrame Pericárdico/cirurgia Pericardite Constritiva/fisiopatologia
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[Pt] Tipo de publicação: | CASE REPORTS; JOURNAL ARTICLE |
[Em] Mês de entrada: | 1702 |
[Cu] Atualização por classe: | 170817 |
[Lr] Data última revisão:
| 170817 |
[Sb] Subgrupo de revista: | IM |
[Da] Data de entrada para processamento: | 170128 |
[St] Status: | MEDLINE |
[do] DOI: | 10.1186/s13019-017-0567-7 |
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