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[PMID]:29208247
[Au] Autor:de la Rocha JAL; Espinoza LR
[Ad] Endereço:Department of Internal Medicine, Section of Rheumatology, Louisiana State University Health Sciences Center, New Orleans, Louisiana.
[Ti] Título:Assessing the Risk of Aortic Aneurysm in Takayasu Arteritis.
[So] Source:Am J Med Sci;354(6):531-532, 2017 12.
[Is] ISSN:1538-2990
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Aneurisma Aórtico/diagnóstico
Mediadores da Inflamação
Arterite de Takayasu/diagnóstico
[Mh] Termos MeSH secundário: Aneurisma Aórtico/sangue
Aneurisma Aórtico/epidemiologia
Biomarcadores/sangue
Seres Humanos
Mediadores da Inflamação/sangue
Fatores de Risco
Arterite de Takayasu/sangue
Arterite de Takayasu/epidemiologia
[Pt] Tipo de publicação:EDITORIAL
[Nm] Nome de substância:
0 (Biomarkers); 0 (Inflammation Mediators)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180301
[Lr] Data última revisão:
180301
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171207
[St] Status:MEDLINE


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[PMID]:29208249
[Au] Autor:Yang KQ; Meng X; Zhang Y; Fan P; Wang LP; Zhang HM; Wu HY; Jiang XJ; Cai J; Zhou XL; Hui RT; Zheng DY; Liu LS
[Ad] Endereço:Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
[Ti] Título:Aortic Aneurysm in Takayasu Arteritis.
[So] Source:Am J Med Sci;354(6):539-547, 2017 12.
[Is] ISSN:1538-2990
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Aortic aneurysm (AA) is a severe complication of Takayasu arteritis (TA). This study aimed to evaluate the prevalence, clinical and imaging features, management and long-term outcomes of AA in patients with TA. MATERIALS AND METHODS: A retrospective study was performed of TA patients with AA admitted to Fuwai Hospital from 1996-2015. Baseline clinical data and follow-up data of TA patients with AA were collected and analyzed. RESULTS: Thirty-nine (4.2%) of 934 patients with TA were identified with AA that was related to vasculitis. The mean age at disease onset was 31 ± 10 years, with a female-to-male ratio of 1.79:1. The ascending aorta was the most common site of the aneurysmal lesion (18, 33.3%), and the most frequent manifestations associated with AA were chest tightness (12, 30.8%) and shortness of breath (12, 30.8%), which were usually concomitant with aortic valve insufficiency. Involvement of multiple sites in AA was found in 8 patients (20.5%), and multiple AAs were found in 5 patients (12.8%). No significant difference was observed in clinical and imaging findings between sexes. Of 25 patients (64.1%) with a median 72-month follow-up, 1 patient suffered from heart failure owing to perivalvular leakage, and 1 patient died, possibly related to severe complications of the operation. CONCLUSIONS: The prevalence of AA is relatively low in Chinese patients with TA. AA seems to develop more frequently in male patients with TA. Management should consider location and size of AA, complexity of vessel lesions and disease status. Long-term follow-up is indispensable.
[Mh] Termos MeSH primário: Aneurisma Aórtico/etiologia
Arterite de Takayasu/complicações
[Mh] Termos MeSH secundário: Adulto
Aneurisma Aórtico/diagnóstico
Aneurisma Aórtico/epidemiologia
Aneurisma Aórtico/patologia
Dor no Peito/etiologia
Angiografia por Tomografia Computadorizada
Dispneia/etiologia
Feminino
Seres Humanos
Masculino
Prevalência
Estudos Retrospectivos
Fatores Sexuais
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1712
[Cu] Atualização por classe:180223
[Lr] Data última revisão:
180223
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171207
[St] Status:MEDLINE


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[PMID]:29314801
[Au] Autor:Popovic R; Radovinovic-Tasic S; Rusovic S; Lepic T; Ilic R; Raicevic R; Obradovic D
[Ti] Título:Urgent carotid stenting before cardiac surgery in a young male patient with acute ischemic stroke caused by aortic and carotid dissection.
[So] Source:Vojnosanit Pregl;73(7):674-8, 2016 Jul.
[Is] ISSN:0042-8450
[Cp] País de publicação:Serbia
[La] Idioma:eng
[Ab] Resumo:Introduction: Acute aortic dissection (AD) is the most common life-threatening disorder affecting the aorta. Neurological symptoms are present in 17-40% of cases. The management of these patients is controversial. Case report: We presented a 37-year-old man admitted for complaining of left-sided weak-ness. Symptoms appeared two hours before admission. The patient had no headache, neither thoracic pain. Neurological examination showed mild confusion, left-sided hemiplegia, National Institutes of Health Stroke Scale (NIHSS) score was 10. Ischemic stroke was suspected, brain multislice computed tomography (MSCT) and angiography were performed and right intrapetrous internal carotid artery dissection noted. Subsequent color Doppler ultrasound of the carotid arteries showed dissection of the right common carotid artery (CCA). The patient underwent thoracic and abdominal MSCT aortography which showed ascending aortic dissection from the aortic root, propagating in the brachiocephalic artery and the right CCA. Digital subtraction angiography was performed subsequently and two stents were successfully implanted in the brachiocephalic artery and the right CCA prior to cardiac surgery, only 6 hours after admission. The ascending aorta was reconstructed with graft interposition and the aortic valve re-suspended. The patient was hemodynamically stable and with no neurologic deficit after surgery. Unfortinately, at the operative day 6, mediastinitis developed and after intensive treatment the patients died 35 days after admission. Conclusion: In young patients with suspected stroke and oscillatory neurological impairment urgent MSCT angiography of the brain and neck and/or Doppler sonography of the carotid and vertebral artery are mandatory to exclude carotid and aortic dissection. The prompt diagnosis permits urgent carotid stenting and cardiosurgery. To the best of our knowledge, this is the first published case of immediate carotid stenting in acute ischemic stroke after the diagnosis of carotid and aortic dissection and prior to cardiac surgery
[Mh] Termos MeSH primário: Aneurisma Dissecante/cirurgia
Aneurisma Aórtico/cirurgia
Isquemia Encefálica/etiologia
Doenças das Artérias Carótidas/cirurgia
Artéria Carótida Primitiva/cirurgia
Stents
[Mh] Termos MeSH secundário: Adulto
Aneurisma Dissecante/complicações
Aneurisma Dissecante/diagnóstico por imagem
Aneurisma Aórtico/complicações
Aneurisma Aórtico/diagnóstico por imagem
Doenças das Artérias Carótidas/complicações
Doenças das Artérias Carótidas/diagnóstico por imagem
Artéria Carótida Primitiva/diagnóstico por imagem
Angiografia por Tomografia Computadorizada
Seres Humanos
Masculino
Tomografia Computadorizada Multidetectores
Ultrassonografia Doppler em Cores
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180213
[Lr] Data última revisão:
180213
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180110
[St] Status:MEDLINE
[do] DOI:10.2298/VSP150402091P


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[PMID]:28455451
[Au] Autor:Okamura H; Emrich F; Trojan J; Chiu P; Dalal AR; Arakawa M; Sato T; Penov K; Koyano T; Pedroza A; Connolly AJ; Rabinovitch M; Alvira C; Fischbein MP
[Ad] Endereço:Department of Cardiothoracic Surgery, Stanford University, Stanford, California.
[Ti] Título:Long-term miR-29b suppression reduces aneurysm formation in a Marfan mouse model.
[So] Source:Physiol Rep;5(8), 2017 Apr.
[Is] ISSN:2051-817X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Aortic root aneurysm formation and subsequent dissection and/or rupture remain the leading cause of death in patients with Marfan syndrome. Our laboratory has reported that miR-29b participates in aortic root/ascending aorta extracellular matrix remodeling during early aneurysm formation in Marfan mice. Herein, we sought to determine whether miR-29b suppression can reduce aneurysm formation long-term. Marfan mice were treated with retro-orbital LNA-anti-miR-29b inhibitor or scrambled-control-miR before aneurysms develop either (1) a single dose prenatally (pregnant mice at 14.5 days post-coitum) ( = 8-10, each group) or (2) postnatally every other week, from 2 to 22 weeks of age, and sacrificed at 24 weeks ( = 8-10, each group). To determine if miR-29b blockade was beneficial even after aneurysms develop, a third group of animals were treated every other week, starting at 8 weeks of age, until sacrificed ( = 4-6, each group). miR-29b inhibition resulted in aneurysm reduction, increased elastogenesis, decreased matrix metalloproteinase activity and decreased elastin breakdown. Prenatal LNA-anti-miR-29b inhibitor treatment decreased aneurysm formation up to age 32 weeks, whereas postnatal treatment was effective up to 16 weeks. miR-29b blockade did not slow aortic growth once aneurysms already developed. Systemic miR-29b inhibition significantly reduces aneurysm development long-term in a Marfan mouse model. Drug administration during aortic wall embryologic development appears fundamental. miR-29b suppression could be a potential therapeutic target for reducing aneurysm formation in Marfan syndrome patients.
[Mh] Termos MeSH primário: Aneurisma Aórtico/prevenção & controle
Terapia Genética/métodos
Síndrome de Marfan/terapia
MicroRNAs/antagonistas & inibidores
[Mh] Termos MeSH secundário: Animais
Aneurisma Aórtico/diagnóstico por imagem
Aneurisma Aórtico/etiologia
Aneurisma Aórtico/patologia
Modelos Animais de Doenças
Progressão da Doença
Ecocardiografia
Elastina/metabolismo
Matriz Extracelular/fisiologia
Feminino
Terapias Fetais/métodos
Masculino
Síndrome de Marfan/complicações
Síndrome de Marfan/genética
Metaloproteinases da Matriz/fisiologia
Camundongos Endogâmicos C57BL
Camundongos Mutantes
Terapia de Alvo Molecular/métodos
Cuidado Pré-Natal/métodos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (MIRN29 microRNA, mouse); 0 (MicroRNAs); 9007-58-3 (Elastin); EC 3.4.24.- (Matrix Metalloproteinases)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180214
[Lr] Data última revisão:
180214
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170430
[St] Status:MEDLINE


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[PMID]:29216679
[Au] Autor:Sultan I; Habertheuer A; Wallen T; Siki M; Szeto W; Bavaria JE; Williams M; Vallabhajosyula P
[Ad] Endereço:Division of Cardiac Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania.
[Ti] Título:The role of extracorporeal membrane oxygenator therapy in the setting of Type A aortic dissection.
[So] Source:J Card Surg;32(12):822-825, 2017 Dec.
[Is] ISSN:1540-8191
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND AND AIM: Patients presenting with type A aortic dissection (TAAD) present with a wide clinical spectrum ranging from hemodynamic stability to multiorgan malperfusion with cardiovascular collapse. Extracorporeal membrane oxygenator (ECMO) therapy is increasingly being utilized as salvage therapy in patients with acute cardiopulmonary failure and for post-cardiotomy shock. We sought to determine the utility of ECMO implementation post-TAAD repair. METHODS: The Pennsylvania Health Care Cost Containment Council (PHC4) database, maintained by an independently functioning state agency, was retrospectively reviewed from 2004 to 2014. Patients with a primary diagnosis of aortic dissection requiring ECMO support during the same hospital visit were included in the analysis. RESULTS: Thirty-nine patients were identified with diagnosis/procedure codes for TAAD repair and ECMO, of which four patients did not undergo TAAD repair. Of the remaining 35, 31 patients underwent open repair, and four patients underwent TEVAR. ECMO was instituted on the same day of TAAD surgery in 27 (69.2%) patients, and on post-operative day >1 in eight (20.5%) patients. Overall mortality in patients who were on ECMO the same day was 88.9% and 87.5% when it was done after the first post-operative day. All four patients with TAAD who underwent ECMO only died. Median time from ECMO implantation to death was 1.0 day. CONCLUSIONS: Requirement for ECMO support in acute aortic dissection is associated with extremely high mortality irrespective of when the intervention is performed.
[Mh] Termos MeSH primário: Aneurisma Dissecante/cirurgia
Aneurisma Aórtico/cirurgia
Oxigenação por Membrana Extracorpórea
Cuidados Pós-Operatórios/métodos
Choque Cirúrgico/terapia
[Mh] Termos MeSH secundário: Adulto
Idoso
Bases de Dados Factuais
Feminino
Seres Humanos
Masculino
Meia-Idade
Estudos Retrospectivos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180129
[Lr] Data última revisão:
180129
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171208
[St] Status:MEDLINE
[do] DOI:10.1111/jocs.13245


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[PMID]:28468757
[Au] Autor:Franken R; Teixido-Tura G; Brion M; Forteza A; Rodriguez-Palomares J; Gutierrez L; Garcia Dorado D; Pals G; Mulder BJ; Evangelista A
[Ad] Endereço:Servei de Cardiologia, Unitat de Marfan, Hospital Universitari, Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain.
[Ti] Título:Relationship between fibrillin-1 genotype and severity of cardiovascular involvement in Marfan syndrome.
[So] Source:Heart;103(22):1795-1799, 2017 11.
[Is] ISSN:1468-201X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The effect of mutation type on the severity of cardiovascular manifestations in patients with Marfan syndrome (MFS) has been reported with disparity results. OBJECTIVES: This study aims to determine the impact of the mutation type on aortic diameters, aortic dilation rates and on cardiovascular events (ie, aortic dissection and cardiovascular mortality). METHODS: MFS patients with a pathogenic mutation followed at two specialised units were included. mutations were classified as being dominant negative (DN; incorporation of non-mutated and mutated fibrillin-1 in the extracellular matrix) or having haploinsufficiency (HI; only incorporation of non-mutated fibrillin-1, thus a decreased amount of fibrillin-1 protein). Aortic diameters and the aortic dilation rate at the level of the aortic root, ascending aorta, arch, descending thoracic aorta and abdominal aorta by echocardiography and clinical endpoints comprising dissection and death were compared between HI and DN patients. RESULTS: Two hundred and ninety patients with MFS were included: 113 (39%) with an HI- mutation and 177 (61%) with a DN- . At baseline, patients with HI- had a larger aortic root diameter than patients with DN- (HI: 39.3±7.2 mm vs DN: 37.3±6.8 mm, p=0.022), with no differences in age or body surface area. After a mean follow-up of 4.9±2.0 years, aortic root and ascending dilation rates were increased in patients with HI- (HI: 0.57±0.8 vs DN: 0.28±0.5 mm/year, p=0.004 and HI: 0.59±0.9 vs DN: 0.30±0.7 mm/year, p=0.032, respectively). Furthermore, patients with HI- tended to be at increased risk for the combined endpoint of dissection and death compared with patients with DN- (HR: 3.3, 95% CI 1.0 to 11.4, p=0.060). CONCLUSIONS: Patients with an HI mutation had a more severely affected aortic phenotype, with larger aortic root diameters and a more rapid dilation rate, and tended to have an increased risk of death and dissections compared with patients with a DN mutation.
[Mh] Termos MeSH primário: Aneurisma Dissecante/genética
Aorta/patologia
Aneurisma Aórtico/genética
Fibrilina-1/genética
Síndrome de Marfan/genética
Mutação
[Mh] Termos MeSH secundário: Adolescente
Adulto
Aneurisma Dissecante/diagnóstico por imagem
Aneurisma Dissecante/metabolismo
Aorta/diagnóstico por imagem
Aneurisma Aórtico/diagnóstico por imagem
Aneurisma Aórtico/mortalidade
Análise Mutacional de DNA
Dilatação Patológica
Progressão da Doença
Ecocardiografia
Feminino
Predisposição Genética para Doença
Haploinsuficiência
Seres Humanos
Masculino
Síndrome de Marfan/complicações
Síndrome de Marfan/diagnóstico
Síndrome de Marfan/mortalidade
Meia-Idade
Fenótipo
Valor Preditivo dos Testes
Prognóstico
Estudos Retrospectivos
Fatores de Risco
Índice de Gravidade de Doença
Espanha
Fatores de Tempo
Adulto Jovem
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; MULTICENTER STUDY; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (FBN1 protein, human); 0 (Fibrillin-1)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:180127
[Lr] Data última revisão:
180127
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170505
[St] Status:MEDLINE
[do] DOI:10.1136/heartjnl-2016-310631


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[PMID]:29206410
[Au] Autor:Brown A; Dingle HE; Brywczynski J; McKinney JJ; Slovis CM
[Ti] Título:The 5 Deadly Causes of Chest Pain: Recognizing the potentially lethal causes other than myocardial infarction.
[So] Source:JEMS;42(1):55-63, 2017 01.
[Is] ISSN:0197-2510
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Dor no Peito/etiologia
[Mh] Termos MeSH secundário: Aneurisma Dissecante/complicações
Aneurisma Dissecante/diagnóstico
Aneurisma Aórtico/complicações
Aneurisma Aórtico/diagnóstico
Tamponamento Cardíaco/complicações
Tamponamento Cardíaco/diagnóstico
Diagnóstico Diferencial
Eletrocardiografia
Perfuração Esofágica/complicações
Perfuração Esofágica/diagnóstico
Seres Humanos
Pericardite/complicações
Pericardite/diagnóstico
Pneumotórax/complicações
Pneumotórax/diagnóstico
Embolia Pulmonar/complicações
Embolia Pulmonar/diagnóstico
Fatores de Risco
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180108
[Lr] Data última revisão:
180108
[Sb] Subgrupo de revista:H
[Da] Data de entrada para processamento:171206
[St] Status:MEDLINE


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[PMID]:27776940
[Au] Autor:Drudi LM; Phung K; Ades M; Zuckerman J; Mullie L; Steinmetz OK; Obrand DI; Afilalo J
[Ad] Endereço:Division of Vascular Surgery, McGill University, Montreal, QC, Canada; Centre for Clinical Epidemiology, Lady Davis Institute, Jewish General Hospital, Montreal, QC, Canada.
[Ti] Título:Psoas Muscle Area Predicts All-Cause Mortality After Endovascular and Open Aortic Aneurysm Repair.
[So] Source:Eur J Vasc Endovasc Surg;52(6):764-769, 2016 12.
[Is] ISSN:1532-2165
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: Psoas muscle area (PMA) is a validated surrogate for muscle mass that can be easily measured from a clinical CT scan. This study sought to determine whether PMA was associated with post-operative mortality after endovascular or open aortic aneurysm repair. METHODS: A retrospective review was undertaken of patients who underwent elective endovascular or open aortic aneurysm repair between 2010 and 2015 at a tertiary vascular center in Montreal, Quebec, Canada. Pre-operative CT scan images were analyzed with the CoreSlicer.com software tool to measure PMA at the axial level of the L4 vertebrae. Measurements were made by two independent observers blinded to clinical data. The primary endpoint was all-cause mortality. RESULTS: The cohort consisted of 149 patients with a mean age of 75.6 ± 8.8 years. The mean PMA was 24.0 ± 5.8 cm in males, and 14.3 ± 3.1 cm in females. There were 31 deaths over a mean follow-up of 22.4 months. After adjusting for age, sex, revised cardiac risk index, and surgical approach, Cox regression revealed a graded association between PMA and all-cause mortality with a hazard ratio of 0.86 per cm (95% CI 0.79-0.93). Addition of PMA to the model with the clinical covariates resulted in an improvement in C-statistic from 0.57 to 0.67, and BIC from 307 to 301 (with lower BIC values preferred). CONCLUSIONS: PMA is independently associated with all-cause mortality after elective endovascular and open aortic aneurysm repair, and may be integrated into the pre-operative risk assessment to optimize care in high-risk frail patients.
[Mh] Termos MeSH primário: Aneurisma Aórtico/cirurgia
Aortografia/métodos
Implante de Prótese Vascular/mortalidade
Angiografia por Tomografia Computadorizada
Procedimentos Endovasculares/mortalidade
Fragilidade/diagnóstico por imagem
Músculos Psoas/diagnóstico por imagem
[Mh] Termos MeSH secundário: Idoso
Idoso de 80 Anos ou mais
Aneurisma Aórtico/diagnóstico por imagem
Aneurisma Aórtico/mortalidade
Implante de Prótese Vascular/efeitos adversos
Composição Corporal
Procedimentos Endovasculares/efeitos adversos
Feminino
Idoso Fragilizado
Fragilidade/mortalidade
Fragilidade/fisiopatologia
Nível de Saúde
Seres Humanos
Estimativa de Kaplan-Meier
Masculino
Meia-Idade
Valor Preditivo dos Testes
Modelos de Riscos Proporcionais
Músculos Psoas/fisiopatologia
Quebeque
Estudos Retrospectivos
Medição de Risco
Fatores de Risco
Centros de Atenção Terciária
Fatores de Tempo
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180108
[Lr] Data última revisão:
180108
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161030
[St] Status:MEDLINE


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[PMID]:27771317
[Au] Autor:Clough RE; Nienaber C; Ventikos Y
[Ad] Endereço:Aortic Centre, Hôpital Cardiologique, CHRU Lille, Lille, France. Electronic address: rachel.clough@kcl.ac.uk.
[Ti] Título:Commentary on "Computational Study of Anatomical Risk Factors in Idealized Models of Type B Aortic Dissection".
[So] Source:Eur J Vasc Endovasc Surg;52(6):746, 2016 12.
[Is] ISSN:1532-2165
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Aneurisma Dissecante
Aneurisma Aórtico
[Mh] Termos MeSH secundário: Aneurisma da Aorta Torácica
Seres Humanos
Fatores de Risco
[Pt] Tipo de publicação:JOURNAL ARTICLE; COMMENT
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180101
[Lr] Data última revisão:
180101
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161025
[St] Status:MEDLINE


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[PMID]:29187940
[Au] Autor:Charfeddine S; Abid D; Triki F; Abid L; Kammoun S; Frikha I
[Ad] Endereço:Department of Cardiology, Hedi Chaker University Hospital, Sfax, Tunisia.
[Ti] Título:Unusual case of ruptured sinus of valsalva aneurysm in a pregnant woman.
[So] Source:Pan Afr Med J;27:271, 2017.
[Is] ISSN:1937-8688
[Cp] País de publicação:Uganda
[La] Idioma:eng
[Ab] Resumo:Sinus of Valsalva aneurysms are extremely rare, and usually of a congenital nature. There are few documented cases of this condition during pregnancy, which renders unclear the therapeutic options. We here report the case of a 26 years old pregnant woman who was referred to our cardiac center for the evaluation of a heart murmur. The two-dimensional transthoracic echocardiography allowed quickly to establishthe diagnosis of a ruptured sinus of Valsalva aneurysm into the right ventricle. A successful surgical correction of the ruptured aneurysm was performed with patch repair.
[Mh] Termos MeSH primário: Aneurisma Aórtico/diagnóstico por imagem
Ruptura Aórtica/diagnóstico por imagem
Complicações Cardiovasculares na Gravidez/diagnóstico por imagem
Seio Aórtico/diagnóstico por imagem
[Mh] Termos MeSH secundário: Adulto
Aneurisma Aórtico/cirurgia
Ruptura Aórtica/cirurgia
Ecocardiografia/métodos
Feminino
Sopros Cardíacos/diagnóstico
Ventrículos do Coração/diagnóstico por imagem
Seres Humanos
Gravidez
Complicações Cardiovasculares na Gravidez/cirurgia
Seio Aórtico/cirurgia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171219
[Lr] Data última revisão:
171219
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171201
[St] Status:MEDLINE
[do] DOI:10.11604/pamj.2017.27.271.9741



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