[PMID]: | 28467197 |
[Au] Autor: | Wu HT; Lee KW; Pan WY; Liu AB; Sun CK |
[Ad] Endereço: | 1 Department of Electrical Engineering, National Dong Hwa University, Hualien, Taiwan, R.O.C. |
[Ti] Título: | Difference in bilateral digital volume pulse as a novel non-invasive approach to assessing arteriosclerosis in aged and diabetic subjects: A preliminary study. |
[So] Source: | Diab Vasc Dis Res;14(3):254-257, 2017 May. |
[Is] ISSN: | 1752-8984 |
[Cp] País de publicação: | England |
[La] Idioma: | eng |
[Ab] Resumo: | OBJECTIVE: This study aimed at validating photoplethysmography for assessing bilateral blood pressure differences through investigating the correlations of digital volume pulse with arteriosclerosis risk. METHODS: Totally, 111 subjects (70 healthy and 41 diabetic) were recruited. Demographic, blood pressure and anthropometric data were recorded. Blood was collected for determining serum cholesterol, total triglyceride, total cholesterol, high-/low-density lipoprotein cholesterol, fasting blood sugar and glycated haemoglobin concentrations. Arterial stiffness was assessed with electrocardiogram-based pulse wave velocity, crest time and inter-digital volume pulse differences. RESULTS: Receiver operating characteristic curve demonstrated high inter-digital volume pulse difference sensitivity to glycated haemoglobin level over 6.5%. Linear regression analysis demonstrated significant correlation between inter-digital volume pulse difference and electrocardiogram-based pulse wave velocity ( r = 0.692, p < 0.001). Compared with electrocardiogram-based pulse wave velocity, inter-digital volume pulse difference exhibited highly significant correlations with age, glycated haemoglobin level, pulse pressure, total cholesterol/high-density lipoprotein ratio, crest time, high-density lipoprotein and systolic blood pressure (all ps < 0.001). CONCLUSION: In conclusion, the results not only demonstrated successful application of a novel non-invasive waveform contour index, inter-digital volume pulse difference, in differentiating young from aged subjects and patients with good diabetic control from those with poor diabetic control but also validated its use in identifying arteriosclerosis risks. The results, therefore, endorse its domestic application as non-invasive tool for arteriosclerosis risk screening. |
[Mh] Termos MeSH primário: |
Aterosclerose/diagnóstico Pressão Sanguínea Angiopatias Diabéticas/diagnóstico Dedos/irrigação sanguínea Fotopletismografia
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[Mh] Termos MeSH secundário: |
Adulto Fatores Etários Área Sob a Curva Aterosclerose/sangue Aterosclerose/fisiopatologia Biomarcadores/sangue Glicemia/análise Estudos de Casos e Controles Angiopatias Diabéticas/sangue Angiopatias Diabéticas/fisiopatologia Hemoglobina A Glicada/análise Seres Humanos Modelos Lineares Lipídeos/sangue Projetos Piloto Valor Preditivo dos Testes Dados Preliminares Análise de Onda de Pulso Curva ROC Reprodutibilidade dos Testes Rigidez Vascular Adulto Jovem
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[Pt] Tipo de publicação: | COMPARATIVE STUDY; JOURNAL ARTICLE; VALIDATION STUDIES |
[Nm] Nome de substância:
| 0 (Biomarkers); 0 (Blood Glucose); 0 (Glycated Hemoglobin A); 0 (Lipids); 0 (hemoglobin A1c protein, human) |
[Em] Mês de entrada: | 1712 |
[Cu] Atualização por classe: | 171219 |
[Lr] Data última revisão:
| 171219 |
[Sb] Subgrupo de revista: | IM |
[Da] Data de entrada para processamento: | 170504 |
[St] Status: | MEDLINE |
[do] DOI: | 10.1177/1479164116688870 |
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