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[PMID]:29466149
[Au] Autor:Knuesel SJ; Guseh JS; Karp Leaf R; Ciaranello AL; Eng GM
[Ad] Endereço:From the Departments of Medicine (S.J.K., J.S.G., R.K.L., A.L.C.) and Pathology (G.M.E.), Massachusetts General Hospital, and the Departments of Medicine (S.J.K., J.S.G., R.K.L., A.L.C.) and Pathology (G.M.E.), Harvard Medical School - both in Boston.
[Ti] Título:Case 6-2018: A 35-Year-Old Woman with Headache, Subjective Fever, and Anemia.
[So] Source:N Engl J Med;378(8):753-760, 2018 Feb 22.
[Is] ISSN:1533-4406
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Anemia Hemolítica Autoimune/diagnóstico
Anemia/etiologia
Eritema Infeccioso/diagnóstico
[Mh] Termos MeSH secundário: Adulto
Anemia Hemolítica Autoimune/etiologia
Doença de Crohn/complicações
Doença de Crohn/tratamento farmacológico
Diagnóstico Diferencial
Eritema Infeccioso/complicações
Feminino
Morte Fetal/etiologia
Febre/etiologia
Cefaleia/etiologia
Seres Humanos
Hospedeiro Imunocomprometido
Parvovirus B19 Humano/isolamento & purificação
Gravidez
Complicações Infecciosas na Gravidez
Viremia
[Pt] Tipo de publicação:CASE REPORTS; CLINICAL CONFERENCE; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180228
[Lr] Data última revisão:
180228
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180222
[St] Status:MEDLINE
[do] DOI:10.1056/NEJMcpc1712223


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[PMID]:29277816
[Au] Autor:Sreedhar A; Nair R; Scialla W
[Ad] Endereço:Department of Internal Medicine, Lehigh Valley Health Network, Allentown, PA, U.S.A. arshasreedhar@gmail.com.
[Ti] Título:Paraneoplastic Auto-immune Hemolytic Anemia: An Unusual Sequela of Enteric Duplication Cyst.
[So] Source:Anticancer Res;38(1):509-512, 2018 01.
[Is] ISSN:1791-7530
[Cp] País de publicação:Greece
[La] Idioma:eng
[Ab] Resumo:Enteric duplication (ED) cysts are rare congenital anomalies of the alimentary canal that present in childhood. Although benign in most case, ED cysts have the potential to cause complications including a rare association with secondary carcinomas. Autoimmune hemolytic anemia presenting as a paraneoplastic syndrome secondary to solid tumors is an unusual phenomenon. Here we report a patient case with ED cyst described in association with intestinal adenocarcinoma and warm-auto immune hemolytic anemia, with resolution of the hemolysis upon its surgical resection.
[Mh] Termos MeSH primário: Adenocarcinoma/diagnóstico
Adenocarcinoma/cirurgia
Anemia Hemolítica Autoimune/tratamento farmacológico
Neoplasias Duodenais/diagnóstico
Neoplasias Duodenais/cirurgia
[Mh] Termos MeSH secundário: Adenocarcinoma/patologia
Anemia Hemolítica Autoimune/diagnóstico
Anemia Hemolítica Autoimune/patologia
Anti-Inflamatórios/uso terapêutico
Cistos/diagnóstico
Cistos/cirurgia
Progressão da Doença
Neoplasias Duodenais/patologia
Duodeno/patologia
Glucocorticoides/uso terapêutico
Seres Humanos
Masculino
Meia-Idade
Prednisona/uso terapêutico
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Inflammatory Agents); 0 (Glucocorticoids); VB0R961HZT (Prednisone)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180104
[Lr] Data última revisão:
180104
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171227
[St] Status:MEDLINE


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[PMID]:29245301
[Au] Autor:Lee CF; Chen CH; Wen YC; Chang TY; Lai MW; Jaing TH
[Ad] Endereço:aDivision of Clinical Pharmacy, Department of Pharmacy, Chang Gung Memorial Hospital, TaoyuanbDepartment of Nursing, Chang Gung Memorial Hospital, TaoyuancDivisions of Hematology/Oncology, Department of Pediatrics, Chang Gung Children's Hospital, Chang Gung University, TaoyuandDivision of Pediatric Gastroenterology, Department of Pediatrics, Chang Gung Children's Hospital, Chang Gung University, TaoyuaneLiver Research Center, Department of Hepato-Gastroenterology, Chang Gung Memorial Hospital, Linkou, Taiwan.
[Ti] Título:Copper-associated hepatitis in a patient with chronic myeloid leukemia following hematopoietic stem cell transplantation: A case report.
[So] Source:Medicine (Baltimore);96(49):e9041, 2017 Dec.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:RATIONALE: We report a complicated case of cholestatic hepatitis with suspected autoimmune hemolytic anemia (AIHA) and copper toxicity syndrome after HSCT and donor lymphocyte infusion (DLI). PATIENT CONCERNS: A 19-year-1-month-old girl presented with a history of CML. She underwent matched unrelated donor HSCT and donor lymphocyte infusion subsequently. Three months later, yellowish discoloration of the skin was found, which was accompanied by progressive itchy skin, easy fatigability, insomnia, and dark urine output. After admission, liver function disorders were observed. INTERVENTION: Methylprednisolone was administered for suspected hepatic GVHD. Although abdominal sonography revealed no evidence of biliary tract obstruction and the viral hepatitis survey disclosed unremarkable findings; silymarin and ursodeoxycholic acid were administered to preserve the liver function. In addition, rituximab was prescribed for suspected AIHA. Because hyperbilirubinemia was progressive, mycophenolate and high-dose intravenous immunoglobulin were accordingly administered. As drug-induced liver injury cannot be excluded, all potential unconfirmed causes of drug-related hepatoxicity were discontinued. DIAGNOSIS: In this case, the patient's history of shrimps and chocolate consumption led us to strongly suspect cholestatic hepatitis associated with copper toxicity syndrome. High 24-hour urine copper excretion and low serum zinc levels were also confirmed. Accordingly, D-penicillamine and zinc gluconate were administered. OUTCOMES: She succumbed to progressive hepatic failure and eventual multisystem organ failure 14 months after HSCT. No autopsy was performed. LESSONS: This report described the combined effects of hepatic GVHD, AIHA, drugs, and copper toxicity on liver damage, and demonstrated the potential diagnostic challenges and treatment dilemmas associated with this disease.
[Mh] Termos MeSH primário: Doença Hepática Induzida por Substâncias e Drogas/etiologia
Cobre/toxicidade
Doença Enxerto-Hospedeiro/etiologia
Transplante de Células-Tronco Hematopoéticas/efeitos adversos
Leucemia Mielogênica Crônica BCR-ABL Positiva/complicações
[Mh] Termos MeSH secundário: Anemia Hemolítica Autoimune/etiologia
Feminino
Seres Humanos
Adulto Jovem
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
789U1901C5 (Copper)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171226
[Lr] Data última revisão:
171226
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171217
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000009041


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[PMID]:28937520
[Au] Autor:Martínez-Valdez L; Deyà-Martínez A; Giner MT; Berrueco R; Esteve-Solé A; Juan M; Plaza-Martín AM; Alsina L
[Ad] Endereço:Departments of *Allergy and Clinical Immunology ‡Hematology and Oncology, Hospital Sant Joan de Dèu, Institut de Recerca Pediàtrica Hospital Sant Joan de Dèu, Esplugues de Llobregat §Immunology Department, Hospital Clinic-IDIBAPS, Universitat de Barcelona †Functional Unit of Clinical Immunology SJD-Clinic, Barcelona, Spain.
[Ti] Título:Evans Syndrome as First Manifestation of Primary Immunodeficiency in Clinical Practice.
[So] Source:J Pediatr Hematol Oncol;39(7):490-494, 2017 Oct.
[Is] ISSN:1536-3678
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Evans syndrome (ES) is a rare immune disorder in children, manifested by simultaneous or sequential autoimmune cytopenias (ACs) of unknown cause and having a chronic course with periods of exacerbation and remission. Some primary immunodeficiencies (PIDs) may present with autoimmune manifestations without infections, masking suspicion of them. The PIDs that can typically manifest as ES are autoimmune lymphoproliferative syndrome and common variable immunodeficiency (CVID). MATERIALS AND METHODS: Review of clinical charts and laboratory results of pediatric patients followed-up in the outpatient clinic of PID with a diagnosis of ES and humoral immunodeficiency. RESULTS: Three pediatric patients, a boy and 2 girls, presented with corticosteroid-dependent ES. In the diagnostic approach, autoimmune lymphoproliferative syndrome was ruled out, and during follow-up, patients showed laboratory signs of humoral immune deficiency and were diagnosed with CVID. After initiating the recommended treatment for CVID with AC, patients improved without new exacerbations. CONCLUSIONS: These cases highlight the importance of detection of possible PID in the context of ES and the establishment of CVID treatment to control AC.
[Mh] Termos MeSH primário: Anemia Hemolítica Autoimune/imunologia
Imunodeficiência de Variável Comum/diagnóstico
Síndromes de Imunodeficiência/patologia
Trombocitopenia/imunologia
[Mh] Termos MeSH secundário: Síndrome Linfoproliferativa Autoimune
Criança
Pré-Escolar
Imunodeficiência de Variável Comum/terapia
Diagnóstico Diferencial
Feminino
Seres Humanos
Masculino
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Evans Syndrome)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171025
[Lr] Data última revisão:
171025
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170923
[St] Status:MEDLINE
[do] DOI:10.1097/MPH.0000000000000880


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[PMID]:28700492
[Au] Autor:Kelkar AH; Shah AA; Yong SL; Ahmed Z
[Ad] Endereço:aDepartment of Internal Medicine bDepartment of Pathology, University of Illinois College of Medicine at Peoria, Peoria cDepartment of Gastroenterology, University of Illinois College of Medicine at Chicago, Chicago, IL.
[Ti] Título:An unusual association between hemophagocytic lymphohistiocytosis, mixed connective tissue disease, and autoimmune hemolytic anemia: A case report.
[So] Source:Medicine (Baltimore);96(28):e7488, 2017 Jul.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:RATIONALE: In the adult patient, hemophagocytic lymphohistiocytosis (HLH) is uncommon and frequently difficult to diagnose due to its nonspecific presentation and numerous complications. PATIENT CONCERNS: Herein, we present the case of a 25-year-old female who initially presented for evaluation of persistent fevers and fatigue. She was found to have splenomegaly, generalized lymphadenopathy, pancytopenia, and acute hepatic failure. DIAGNOSES, INTERVENTIONS, AND OUTCOMES: Her course was further complicated by the development of nephrotic syndrome and autoimmune hemolytic anemia (AIHA). Antinuclear antibody and ribonucleoprotein were positive, with concurrent physical examination findings, indicating underlying mixed connective tissue disease (MCTD). Ferritin was greater than 40,000 ng/dL. Viral studies, including hepatitis A, B, and C, cytomegalovirus, and Epstein-Barr virus were negative. On the basis of her clinical presentation, a diagnosis of HLH secondary to MCTD was made. This was later confirmed on liver biopsy. She was started on high-dose prednisone and her symptoms completely resolved. She was then transitioned to azathioprine, hydroxychloroquine, prophylactic antibiotics, and a prednisone taper for long-term management. LESSONS: This case is notable for the association of both AIHA and MCTD with HLH, providing support for a possible relationship between these 3 conditions.
[Mh] Termos MeSH primário: Anemia Hemolítica Autoimune/complicações
Anemia Hemolítica Autoimune/diagnóstico
Linfo-Histiocitose Hemofagocítica/diagnóstico
Linfo-Histiocitose Hemofagocítica/etiologia
Doença Mista do Tecido Conjuntivo/complicações
Doença Mista do Tecido Conjuntivo/diagnóstico
[Mh] Termos MeSH secundário: Adulto
Anemia Hemolítica Autoimune/tratamento farmacológico
Anemia Hemolítica Autoimune/patologia
Diagnóstico Diferencial
Feminino
Seres Humanos
Linfo-Histiocitose Hemofagocítica/tratamento farmacológico
Linfo-Histiocitose Hemofagocítica/patologia
Doença Mista do Tecido Conjuntivo/tratamento farmacológico
Doença Mista do Tecido Conjuntivo/patologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170730
[Lr] Data última revisão:
170730
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170713
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000007488


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[PMID]:28687137
[Au] Autor:Lauda-Maillen M; Catroux M; Roy-Peaud F; Souchaud-Debouverie O; El Masmouhi B; Roblot P
[Ad] Endereço:Service de médecine interne et maladies infectieuses, université de Poitiers, CHU de Poitiers, 2, rue de la Milétrie, BP 577, 86021 Poitiers, France. Electronic address: maider_lauda@hotmail.com.
[Ti] Título:[Diagnosis and management of acquired immune haemolytic anaemia excluding neoplasia. Adequacy with the current guidelines published in 2009].
[Ti] Título:Diagnostic et prise en charge de l'anémie hémolytique auto-immune à l'exclusion des formes secondaires à une cause néoplasique. Adéquation de la prise en charge au PNDS octobre 2009..
[So] Source:Rev Med Interne;38(10):648-655, 2017 Oct.
[Is] ISSN:1768-3122
[Cp] País de publicação:France
[La] Idioma:fre
[Ab] Resumo:OBJECTIVES: Describe the management of Acquired Immune Haemolytic Anaemia (AIHA) and correlate with the current guidelines published in 2009. The secondary objective was to calculate the positive predictive value of the Direct Antiglobulin Test (DAT) for the diagnosis of AIHA. METHODS: A retrospective and monocentric study was performed from 2010 to 2015 based on positive DATs, identified in the French Blood Agency database or in medical files. All patients managed for initial diagnosis or relapse of AIHA were included, excluding neoplasia. RESULTS: Six hundred and twenty-three patients had a positive DAT, 42 had non-neoplastic AIHA. Thirty-nine patients were included, 32 had warm antibodies, 5 had a negative DAT and 2 had cold antibodies. No cause was found for 46% (17/37) of the warm antibody and negative DATs AIHAs. Autoimmune disease was found in 11 cases (30%), infection in 4 cases (11%). The etiologic investigations were consistent with the guidelines in 49% of cases. Corticosteroids were first prescribed, as recommended. Second-line treatments were rituximab in 9 cases, splenectomy in 4 cases and azathioprine in 3 cases. The management of cold antibody AIHA complied with the guidelines. The positive predictive value of DATs in hospitalized population was of 14% (85/610). CONCLUSION: AIHA guidelines seem insufficiently applied in our center.
[Mh] Termos MeSH primário: Anemia Hemolítica Autoimune/diagnóstico
Anemia Hemolítica Autoimune/terapia
Guias de Prática Clínica como Assunto/normas
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Idoso de 80 Anos ou mais
Anemia Hemolítica/diagnóstico
Anemia Hemolítica/etiologia
Anemia Hemolítica/terapia
Anemia Hemolítica Autoimune/sangue
Autoanticorpos/sangue
Criança
Pré-Escolar
Teste de Coombs
Diagnóstico Diferencial
Feminino
Seres Humanos
Masculino
Meia-Idade
Neoplasias/complicações
Neoplasias/diagnóstico
Valor Preditivo dos Testes
Estudos Retrospectivos
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Autoantibodies)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171031
[Lr] Data última revisão:
171031
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170709
[St] Status:MEDLINE


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[PMID]:28654461
[Au] Autor:Mantadakis E; Farmaki E
[Ad] Endereço:*Department of Pediatrics, University General Hospital of Evros, Alexandroupolis, Thrace †First Department of Pediatrics, Pediatric Immunology and Rheumatology Referral Centre, Ippokration General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
[Ti] Título:Natural History, Pathogenesis, and Treatment of Evans Syndrome in Children.
[So] Source:J Pediatr Hematol Oncol;39(6):413-419, 2017 Aug.
[Is] ISSN:1536-3678
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Primary Evans syndrome (ES) is defined by the concurrent or sequential occurrence of immune thrombocytopenia and autoimmune hemolytic anemia in the absence of an underlying etiology. The syndrome is characterized by a chronic, relapsing, and potentially fatal course requiring long-term immunosuppressive therapy. Treatment of ES is hardly evidence-based. Corticosteroids are the mainstay of therapy. Rituximab has emerged as the most widely used second-line treatment, as it can safely achieve high response rates and postpone splenectomy. An increasing number of new genetic defects involving critical pathways of immune regulation identify specific disorders, which explain cases of ES previously reported as "idiopathic".
[Mh] Termos MeSH primário: Anemia Hemolítica Autoimune/patologia
Anemia Hemolítica Autoimune/terapia
Trombocitopenia/patologia
Trombocitopenia/terapia
[Mh] Termos MeSH secundário: Corticosteroides/uso terapêutico
Anemia Hemolítica Autoimune/etiologia
Anemia Hemolítica Autoimune/mortalidade
Criança
Transplante de Células-Tronco Hematopoéticas
Seres Humanos
Imunossupressão/métodos
Rituximab/uso terapêutico
Esplenectomia
Trombocitopenia/etiologia
Trombocitopenia/mortalidade
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Adrenal Cortex Hormones); 0 (Evans Syndrome); 4F4X42SYQ6 (Rituximab)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170925
[Lr] Data última revisão:
170925
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170628
[St] Status:MEDLINE
[do] DOI:10.1097/MPH.0000000000000897


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[PMID]:28598573
[Au] Autor:Abongwa C; Abusin G; El-Sheikh A
[Ad] Endereço:Division of Pediatric Hematology Oncology, Department of Pediatrics, Loma Linda University, Loma Linda, California.
[Ti] Título:Successful treatment of tacrolimus-related pure red cell aplasia and autoimmune hemolytic anemia with rituximab in a pediatric cardiac transplant patient.
[So] Source:Pediatr Blood Cancer;64(12), 2017 Dec.
[Is] ISSN:1545-5017
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Acquired pure red cell aplasia (PRCA) and autoimmune hemolytic anemia (AIHA) are rare complications of immunosuppression in pediatric solid organ transplant patients. We report a 14-month-old female child who developed Coombs positive hemolytic anemia and reticulocytopenia while on tacrolimus after cardiac transplantation. She was successfully treated with rituximab after failing treatment with corticosteroids and intravenous immunoglobulins. Clinicians should consider PRCA differential diagnosis in a patient presenting with reticulocytopenia and hemolysis. In addition, the coexistence of PRCA with AIHA, and the response to therapy with rituximab, supports a common immune-mediated pathogenesis for both disorders.
[Mh] Termos MeSH primário: Anemia Hemolítica Autoimune/tratamento farmacológico
Transplante de Coração
Imunossupressores/efeitos adversos
Aplasia Pura de Série Vermelha/tratamento farmacológico
Rituximab/uso terapêutico
Tacrolimo/efeitos adversos
[Mh] Termos MeSH secundário: Anemia Hemolítica Autoimune/induzido quimicamente
Feminino
Seres Humanos
Lactente
Aplasia Pura de Série Vermelha/induzido quimicamente
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Immunosuppressive Agents); 4F4X42SYQ6 (Rituximab); WM0HAQ4WNM (Tacrolimus)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171026
[Lr] Data última revisão:
171026
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170610
[St] Status:MEDLINE
[do] DOI:10.1002/pbc.26674


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[PMID]:28586251
[Au] Autor:Barcellini W
[Ad] Endereço:a Onco-hematology Unit , IRCCS Ca' Granda - Maggiore Policlinico Hospital Foundation , Milan , Italy.
[Ti] Título:The relationship between idiopathic cytopenias/dysplasias of uncertain significance (ICUS/IDUS) and autoimmunity.
[So] Source:Expert Rev Hematol;10(7):649-657, 2017 Jul.
[Is] ISSN:1747-4094
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: This review examines the several lines of evidence that support the relationship between myelodysplasia and autoimmunity, i.e. their epidemiologic association, the existence of common immune-mediated physiopathologic mechanisms, and the response to similar immunosuppressive therapies. The same relationship is reviewed here considering idiopathic cytopenia of uncertain significance (ICUS) and idiopathic dysplasia of uncertain significance (IDUS), two recently recognized provisional conditions characterized by isolated/unexplained cytopenia and/or dysplasia in <10% bone marrow cells. Areas covered: The review focuses on alterations of cytokine profiles, telomere/telomerase and toll-like receptors, and on increased myelosuppressive mediators and apoptotic markers in both myelodysplasia and autoimmunity. In addition, the presence of an autoimmune reaction directed against marrow precursors is described in refractory/relapsing autoimmune cytopenias (autoimmune hemolytic anemia, immune thrombocytopenia, chronic idiopathic neutropenia), possibly contributing to their evolution to ICUS/IDUS/bone marrow failure syndromes. Expert commentary: The increasing availability of omics methods has fuelled the discussion on the role of somatic mutations in the pathogenesis of IDUS/ICUS, clonal hematopoiesis of indeterminate potential, and clonal cytopenias of undetermined significance, and in their possible evolution. Even more attracting is the involvement of the genetic background/accumulating somatic mutations in cytopenias with autoimmune alterations.
[Mh] Termos MeSH primário: Autoimunidade
Síndromes Mielodisplásicas/diagnóstico
Síndromes Mielodisplásicas/etiologia
[Mh] Termos MeSH secundário: Anemia Aplástica/imunologia
Anemia Aplástica/metabolismo
Anemia Aplástica/patologia
Anemia Hemolítica Autoimune/complicações
Doenças Autoimunes/complicações
Medula Óssea/patologia
Doenças da Medula Óssea/imunologia
Doenças da Medula Óssea/metabolismo
Doenças da Medula Óssea/patologia
Hemoglobinúria Paroxística/imunologia
Hemoglobinúria Paroxística/metabolismo
Hemoglobinúria Paroxística/patologia
Seres Humanos
Síndromes Mielodisplásicas/metabolismo
Síndromes Mielodisplásicas/terapia
Prognóstico
Púrpura Trombocitopênica Idiopática/complicações
Receptores Toll-Like/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Toll-Like Receptors)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171009
[Lr] Data última revisão:
171009
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170607
[St] Status:MEDLINE
[do] DOI:10.1080/17474086.2017.1339597


  10 / 5187 MEDLINE  
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[PMID]:28584043
[Au] Autor:Shiiya C; Ota M
[Ad] Endereço:Department of Dermatology, Chitose City Hospital, Chitose, Japan.
[Ti] Título:Cold agglutinin disease presenting as livedo racemosa.
[So] Source:CMAJ;189(22):E781, 2017 06 05.
[Is] ISSN:1488-2329
[Cp] País de publicação:Canada
[La] Idioma:eng
[Mh] Termos MeSH primário: Anemia Hemolítica Autoimune/complicações
Anemia Hemolítica Autoimune/diagnóstico
Anemia Hemolítica Autoimune/etiologia
Livedo Reticular/etiologia
[Mh] Termos MeSH secundário: Idoso de 80 Anos ou mais
Anemia Hemolítica Autoimune/terapia
Feminino
Seres Humanos
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171030
[Lr] Data última revisão:
171030
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170607
[St] Status:MEDLINE
[do] DOI:10.1503/cmaj.161407



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BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde