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  1 / 1120 MEDLINE  
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[PMID]:29390256
[Au] Autor:Yu W; Qu W; Wang Z; Xin C; Jing R; Shang Y; Zou H; Wang H; Feng S
[Ad] Endereço:Hematology Department, Yantai Affiliated Hospital, Binzhou Medical University, Yantai.
[Ti] Título:Sjogren's syndrome complicating pancytopenia, cerebral hemorrhage, and damage in nervous system: A case report and literature review.
[So] Source:Medicine (Baltimore);96(50):e8542, 2017 Dec.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:RATIONALE: Sjogren's syndrome(SS) is a chronic autoimmune disease, which damages exocrine glands especially salivary and lacrimal glands, with xerostomia and xerophthalmia as common symptoms. PATIENT CONCERNS: We report a case of a 49-year-old woman presented with pancytopenia. Her laboratory examinations lead us diagnose her as Sjogren's syndrome complicating pancytopenia. She had neurological symptoms during her treatment, which represent only 4.5% of Sjogren's syndrome complicating damage in nervous system. DIAGNOSES: Sjogren's syndrome complicating pancytopenia. INTERVENTIONS: Dexamethasone (40mg QD for 4 days) and immunoglobulin (25g QD for 2 days) were administered for intensive treatment followed by oral methylprednisolone 40mg QD as maintenance treatment. Total glucosides of paeony 0.6g TID and danazol 0.2g BID per os were given. We also gave her Piperacillin-tazobactam and moxifloxacin for anti-infection and Fluconazole for anti-fungal therapy, as well as other supportive treatments. OUTCOMES: Follow-up of the patient observed the normalization of peripheral blood cell count, immunity indices and neurological examinations 6 months after discharge. LESSONS: For patients presented with blood system abnormalities unilineage or multiple-lineage cytopenia in particular, history investigations and relevant examinations should be considered to exclude the existence of autoimmune diseases like Sjogren's syndrome.
[Mh] Termos MeSH primário: Hemorragia Cerebral/etiologia
Pancitopenia/etiologia
Síndrome de Sjogren/complicações
[Mh] Termos MeSH secundário: Dexametasona/uso terapêutico
Equimose/etiologia
Feminino
Glucocorticoides/uso terapêutico
Cefaleia/etiologia
Seres Humanos
Imunoglobulinas Intravenosas/uso terapêutico
Metilprednisolona/uso terapêutico
Meia-Idade
Convulsões/etiologia
Síndrome de Sjogren/tratamento farmacológico
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Glucocorticoids); 0 (Immunoglobulins, Intravenous); 7S5I7G3JQL (Dexamethasone); X4W7ZR7023 (Methylprednisolone)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180301
[Lr] Data última revisão:
180301
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180203
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000008542


  2 / 1120 MEDLINE  
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[PMID]:28457081
[Au] Autor:Ben-Chetrit E; Abu Rmeileh A; Atlan K; Ben-Chetrit E
[Ad] Endereço:Unit of Infectious Diseases, Shaare Zedek Medical Center, Jerusalem, Israel.
[Ti] Título:Willie Sutton Strikes Again.
[So] Source:Isr Med Assoc J;18(12):756-760, 2016 Dec.
[Is] ISSN:1565-1088
[Cp] País de publicação:Israel
[La] Idioma:eng
[Mh] Termos MeSH primário: Hiperesplenismo/diagnóstico
Pancitopenia/etiologia
Esplenomegalia/diagnóstico
[Mh] Termos MeSH secundário: Idoso
Equimose/etiologia
Feminino
Febre/etiologia
Seres Humanos
Hiperesplenismo/etiologia
Esplenomegalia/etiologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171128
[Lr] Data última revisão:
171128
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170501
[St] Status:MEDLINE


  3 / 1120 MEDLINE  
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[PMID]:28863206
[Au] Autor:Ghosh SK; Majumder B; Ghosh S; Das DK; Chatterjee S
[Ad] Endereço:Department of Dermatology, Venereology, and Leprosy, R. G. Kar Medical College and Hospital, West Bengal, India. E-mail: dr_skghosh@yahoo.co.in.
[Ti] Título:Periorbital ecchymoses and breathlessness.
[So] Source:J Fam Pract;66(9):E11-E13, 2017 Sep.
[Is] ISSN:1533-7294
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:A 54-year-old man presented at our facility with a 3-month history of exertional breathlessness and purple blotches around his eyes. Examination revealed bilateral periorbital and perioral ecchymosis, purpuric spots along his waist, and waxy papules on his eyelids. In addition, the patient had macroglossia with nodular infiltration and irregular indentations at the lateral margin of his tongue. The patient also had a raised jugular venous pressure and prominent atrial and ventricular waves. Further examination revealed a fourth heart sound over the left ventricular apex, as well as bilateral basal rales. All other systems were normal except for mild hepatomegaly. Routine hematologic and biochemical lab work was unremarkable. X-rays of the spine and skull were normal, but a chest x-ray showed mild cardiomegaly. An electrocardiogram showed a QS complex from leads V1 to V4 (a pseudo-infarction pattern). An echocardiogram showed biatrial enlargement, left ventricular hypertrophy with a left ventricular ejection fraction of 48%, a speckled pattern on the myocardium, a thickened interatrial septum, and mild pericardial effusion. A color Doppler revealed mild mitral and tricuspid regurgitation with a restrictive pattern of mitral valve flow. Serum protein electrophoresis was normal. WHAT IS YOUR DIAGNOSIS? HOW WOULD YOU TREAT THIS PATIENT?
[Mh] Termos MeSH primário: Dispneia/diagnóstico
Dispneia/terapia
Equimose/diagnóstico
Equimose/terapia
Oftalmopatias/terapia
Cardiopatias/diagnóstico por imagem
Cardiopatias/terapia
[Mh] Termos MeSH secundário: Ecocardiografia
Eletrocardiografia
Oftalmopatias/diagnóstico
Seres Humanos
Masculino
Meia-Idade
Radiografia
Resultado do Tratamento
[Pt] Tipo de publicação:CASE REPORTS
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170918
[Lr] Data última revisão:
170918
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170902
[St] Status:MEDLINE


  4 / 1120 MEDLINE  
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[PMID]:28302629
[Au] Autor:Mitchell LV; Wilson MR; Holmes S
[Ad] Endereço:Walton Building, Glasgow Royal Infirmary, Glasgow, UK.
[Ti] Título:A historic disease still prevalent today.
[So] Source:BMJ;356:j1013, 2017 03 16.
[Is] ISSN:1756-1833
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Escorbuto/diagnóstico
[Mh] Termos MeSH secundário: Idoso
Ácido Ascórbico/uso terapêutico
Equimose/etiologia
Seres Humanos
Dermatoses da Perna/etiologia
Masculino
Escorbuto/complicações
Escorbuto/tratamento farmacológico
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
PQ6CK8PD0R (Ascorbic Acid)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171113
[Lr] Data última revisão:
171113
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170318
[St] Status:MEDLINE
[do] DOI:10.1136/bmj.j1013


  5 / 1120 MEDLINE  
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[PMID]:28212767
[Au] Autor:Gurnee EA; Stoff BK
[Ad] Endereço:Department of Dermatology, Emory University School of Medicine, Atlanta, Georgia.
[Ti] Título:Confronting abusive injuries in dermatology: Ethical and legal considerations.
[So] Source:J Am Acad Dermatol;76(3):573-576, 2017 Mar.
[Is] ISSN:1097-6787
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Dermatologia/ética
Equimose/etiologia
Violência por Parceiro Íntimo
Preferência do Paciente
[Mh] Termos MeSH secundário: Adulto
Criança
Serviços de Proteção Infantil
Feminino
Seres Humanos
Violência por Parceiro Íntimo/legislação & jurisprudência
Notificação Compulsória/ética
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170427
[Lr] Data última revisão:
170427
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170219
[St] Status:MEDLINE


  6 / 1120 MEDLINE  
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[PMID]:28094753
[Au] Autor:Amann J; Wessels AM; Breitenfeldt F; Huscher D; Bijlsma JWJ; Jacobs JWG; Buttgereit F
[Ad] Endereço:Department of Rheumatology and Clinical Immunology, Charité University Medicine, Berlin, Germany.
[Ti] Título:Quantifying cutaneous adverse effects of systemic glucocorticoids in patients with rheumatoid arthritis: a cross-sectional cohort study.
[So] Source:Clin Exp Rheumatol;35(3):471-476, 2017 May-Jun.
[Is] ISSN:0392-856X
[Cp] País de publicação:Italy
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: EULAR guidelines state that adverse effects (AEs) of glucocorticoid (GC) therapy should be considered and discussed with the patient before treatment is initiated. However, reliable quantitative data, especially on cutaneous AEs of low-to-medium dose GCs are lacking. We performed a study assessing the occurrence of cutaneous AEs of GCs and its association with current and cumulative GC doses in patients with rheumatoid arthritis (RA). METHODS: In a cross-sectional study performed in 2 outpatient rheumatology centres, 381 RA patients were enrolled. They were classed into 4 groups, according their mean daily dose during the past 12 months: 0 mg (n=87), <5mg (n=108), 5-7.5 mg (n=130), and >7.5 mg (n=56) of prednisone equivalent. AEs of GC on the skin were assessed by physical examination using a predefined scoring system, and by patients' self-assessments. Data were analysed according GC dose categories and cumulative doses. RESULTS: Cushingoid habitus, easy bruising, skin atrophy, and impaired wound healing as reported by patients occurred significantly more frequently in those using a GC the past 12 months, compared to those not using a GC. At physicians' assessments, only Cushingoid habitus and ecchymosis were more prevalent in GC users. The prevalence of these AEs was statistically significantly positively associated with current and cumulative GC dose. There was low occurrence of abnormal stretch marks, acne, perioral dermatitis, alopecia and hirsutism, which were not correlated with GC use. CONCLUSIONS: Certain GC-associated cutaneous AEs are common in RA, but other AEs of GC occur infrequently at the low-to-medium GC doses used in RA.
[Mh] Termos MeSH primário: Artrite Reumatoide/tratamento farmacológico
Glucocorticoides/efeitos adversos
Dermatopatias/induzido quimicamente
Pele/efeitos dos fármacos
[Mh] Termos MeSH secundário: Idoso
Artrite Reumatoide/diagnóstico
Atrofia
Contusões/induzido quimicamente
Contusões/epidemiologia
Estudos Transversais
Síndrome de Cushing/induzido quimicamente
Síndrome de Cushing/epidemiologia
Relação Dose-Resposta a Droga
Equimose/induzido quimicamente
Equimose/epidemiologia
Feminino
Alemanha/epidemiologia
Glucocorticoides/administração & dosagem
Seres Humanos
Masculino
Meia-Idade
Prevalência
Medição de Risco
Fatores de Risco
Autoavaliação
Pele/patologia
Dermatopatias/diagnóstico
Dermatopatias/epidemiologia
Fatores de Tempo
Resultado do Tratamento
Cicatrização/efeitos dos fármacos
[Pt] Tipo de publicação:JOURNAL ARTICLE; MULTICENTER STUDY
[Nm] Nome de substância:
0 (Glucocorticoids)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170824
[Lr] Data última revisão:
170824
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170118
[St] Status:MEDLINE


  7 / 1120 MEDLINE  
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[PMID]:28043785
[Au] Autor:Giordano S; Koskivuo I; Suominen E; Veräjänkorva E
[Ad] Endereço:Department of Plastic and General Surgery, Turku University Hospital, Turku, Finland; Department of Surgery, Welfare District of Forssa, Forssa, Finland. Electronic address: salvatore.giordano@gmail.com.
[Ti] Título:Tissue sealants may reduce haematoma and complications in face-lifts: A meta-analysis of comparative studies.
[So] Source:J Plast Reconstr Aesthet Surg;70(3):297-306, 2017 Mar.
[Is] ISSN:1878-0539
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:The use of tissue sealants has increased among different surgical specialities. Face-lift and rhytidoplasty may cause several complications such as haematoma, ecchymosis, oedema, seroma, skin necrosis, wound dehiscence and wound infection. However, administration of tissue sealants may prevent the occurrence of some complications. We performed a meta-analysis of studies that compared tissue sealant use with controls to evaluate the outcomes. A systematic literature search was performed. The primary outcome was the incidence of haematoma. Secondary outcomes were wound drainage amount, oedema, ecchymosis, seroma, skin necrosis and hypertrophic scarring. Thirteen studies involving 2434 patients were retrieved and included in the present analysis. A statistically significantly decrease in post-operative haematoma [risk ratio (RR), 0.37; 95% CI, 0.18-0.74; p = 0.005] and wound drainage (MD, -16.90, 95% CI = -25.71, -8.08, p < 0.001) was observed with tissue sealant use. A significant decrease in oedema was detected (RR, 0.30; 95% CI, 0.11-0.85, p = 0.02) but not in ecchymosis, seroma, skin necrosis, and hypertrophic scarring with tissue sealant use. The use of tissue sealants prevents post-operative haematomas and reduces wound drainage. Previous studies have shown a similar trend, but the power of this meta-analysis could verify this perception. LEVEL OF EVIDENCE: III.
[Mh] Termos MeSH primário: Adesivo Tecidual de Fibrina/uso terapêutico
Hematoma/prevenção & controle
Ritidoplastia/métodos
Adesivos Teciduais/uso terapêutico
[Mh] Termos MeSH secundário: Cicatriz Hipertrófica/etiologia
Drenagem/métodos
Equimose/etiologia
Edema/etiologia
Métodos Epidemiológicos
Hematoma/etiologia
Seres Humanos
Plasma Rico em Plaquetas
Complicações Pós-Operatórias/etiologia
Complicações Pós-Operatórias/prevenção & controle
Ritidoplastia/efeitos adversos
Seroma/etiologia
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE; META-ANALYSIS; REVIEW
[Nm] Nome de substância:
0 (Fibrin Tissue Adhesive); 0 (Tissue Adhesives)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170417
[Lr] Data última revisão:
170417
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170104
[St] Status:MEDLINE


  8 / 1120 MEDLINE  
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[PMID]:27978610
[Au] Autor:Emiroglu N; Su O; Cengiz FP; Tosuner Z; Demirkesen C; Onsun N
[Ad] Endereço:Unit of Dermatology, Bezmialem Vakif University, Istanbul, Turkey - dr.nazanyilmaz@hotmail.com.
[Ti] Título:Raccoon eyes in amyloidosis.
[So] Source:G Ital Dermatol Venereol;152(1):80-82, 2017 02.
[Is] ISSN:1827-1820
[Cp] País de publicação:Italy
[La] Idioma:eng
[Mh] Termos MeSH primário: Amiloidose/diagnóstico
Equimose/etiologia
Mieloma Múltiplo/diagnóstico
Doenças Orbitárias/etiologia
[Mh] Termos MeSH secundário: Amiloidose/patologia
Seres Humanos
Masculino
Meia-Idade
Mieloma Múltiplo/patologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170428
[Lr] Data última revisão:
170428
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161217
[St] Status:MEDLINE
[do] DOI:10.23736/S0392-0488.16.05160-9


  9 / 1120 MEDLINE  
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[PMID]:27893019
[Au] Autor:Yu W; Jin Y; Yang J; Ma G; Qiu Y; Chen H; Yang X; Chang L; Lin X
[Ad] Endereço:Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Plastic and Reconstructive Surgery, Shanghai, China.
[Ti] Título:Occurrence of Bruise, Hematoma, and Pain in Upper Blepharoplasty Using Blunt-Needle vs Sharp-Needle Anesthetic Injection in Upper Blepharoplasty: A Randomized Clinical Trial.
[So] Source:JAMA Facial Plast Surg;19(2):128-132, 2017 Mar 01.
[Is] ISSN:2168-6092
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Importance: Though it has been a common practice to use sharp needles to administer local anesthesia for upper blepharoplasty, the evidence for their benefit is lacking. Objective: To evaluate whether there is any benefit of using blunt-needle injection for local anesthesia when performing upper blepharoplasty to reduce postoperative bruise, hematoma, and pain. Design, Setting, and Participants: Randomized clinical trial of 44 patients who underwent bilateral upper blepharoplasty in an academic medical setting were randomized to receive local anesthesia injections (lidocaine, 2%; 27-gauge needle) with a blunt needle in one eyelid and a sharp needle in the other eyelid. Main Outcomes and Measures: Visual analog scale (VAS) score of 0 to 10 (lower score indicating lower level of pain) was used to blindly assess pain in patients receiving anesthesia injections with both needle types. After injection and skin incision, photographs of the eyelids of each patient were taken and used by 2 blinded observers to identify bruise or hematoma. Results: In the 44 patients (88 eyelids) included in the study (all women; mean age, 31 years; age range, 18-56 years) bruise or hematoma occurred at the sharp-needle injection site in 11 women (25%) vs 0 women at the blunt-needle site (P < .001). The mean VAS scores were 5.48 and 4.64 for pain assessed at sites of sharp- and blunt-needle injections, respectively (P = .002). Conclusions and Relevance: Use of blunt needles to administer local anesthesia when performing upper blepharoplasty is less likely to cause hemorrhage and require interventional pain procedures than use of sharp needles. Therefore, for a more accurate surgical procedure and faster recovery, a blunt needle may be a preferable choice. The use of the blunt needle presents fewer complications and allows more accurate and refined work with faster patient recovery. Level of Evidence: 1. Trial Registration: Chinese Clinical Trial Registry identifier: ChiCTR-ONC-16007979.
[Mh] Termos MeSH primário: Anestésicos Locais/administração & dosagem
Blefaroplastia/métodos
Equimose/etiologia
Hematoma/etiologia
Lidocaína/administração & dosagem
Agulhas/efeitos adversos
Complicações Pós-Operatórias/etiologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Desenho de Equipamento
Feminino
Seres Humanos
Meia-Idade
Medição da Dor
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (Anesthetics, Local); 98PI200987 (Lidocaine)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170420
[Lr] Data última revisão:
170420
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161129
[St] Status:MEDLINE
[do] DOI:10.1001/jamafacial.2016.1376


  10 / 1120 MEDLINE  
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[PMID]:27667126
[Au] Autor:Lim G; Irfan M; Bergfeld WF; Sood A
[Ad] Endereço:Department of Internal Medicine, Mount Sinai Beth Israel, New York, NY, USA.
[Ti] Título:Abdominal pannus with verrucous nodules, ecchymosis, and ulcerations in the setting of lymphedema.
[So] Source:Int J Dermatol;56(2):e16-e18, 2017 Feb.
[Is] ISSN:1365-4632
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Equimose/etiologia
Hemangiossarcoma/diagnóstico
Neoplasias Pulmonares/secundário
Linfedema/etiologia
Neoplasias Cutâneas/diagnóstico
Úlcera Cutânea/etiologia
[Mh] Termos MeSH secundário: Abdome
Idoso
Feminino
Hemangiossarcoma/complicações
Hemangiossarcoma/secundário
Seres Humanos
Obesidade Mórbida/complicações
Neoplasias Cutâneas/complicações
Neoplasias Cutâneas/patologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170804
[Lr] Data última revisão:
170804
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160927
[St] Status:MEDLINE
[do] DOI:10.1111/ijd.13356



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