[PMID]: | 29390329 |
[Au] Autor: | Zhou Z; Jiang W; Wang M; Liu Y; Zhang W; Huang M; Liang D |
[Ti] Título: | Primary Sjögren syndrome that initially presented with repeated hypergammaglobulinemic purpura after prolonged sitting: A case report. |
[So] Source: | Medicine (Baltimore);96(50):e9187, 2017 Dec. |
[Is] ISSN: | 1536-5964 |
[Cp] País de publicação: | United States |
[La] Idioma: | eng |
[Ab] Resumo: | RATIONALE: Purpura is a common dermatologic manifestation in Sjögren syndrome (SS). When a patient presents with sicca symptoms, the diagnosis of SS is not difficult. PATIENT CONCERNS: Here, we reported a case of a 52-year-old Chinese woman who initially presented with nonpalpable purpura on both lower extremities, and these lesions had developed soon after prolonged sitting. In the past 2 years, she had repeated cutaneous nonpalpable purpura 4 times. She had no sicca symptoms, dry eyes, or dry mouth. DIAGNOSES: Combining the laboratory findings, Schirmer test, and labial gland biopsy, primary SS was confirmed. INTERVENTIONS: The patient was placed on a trial of hydroxychloroquine (200 mg once daily). OUTCOMES: The purpura on both lower extremities had faded at the sixth day after onset and at the third day after hydroxychloroquine treatment. LESSONS: These case was not easy to diagnosis primary SS because she had no sicca symptoms. A patient with primary SS who initially presented with recurrent purpura associated with prolonged sitting. Prolonged sitting had been a possible aggravating factor for the cutaneous purpura of this patient with primary SS. |
[Mh] Termos MeSH primário: |
Antirreumáticos/uso terapêutico Hidroxicloroquina/uso terapêutico Hipergamaglobulinemia/diagnóstico Hipergamaglobulinemia/tratamento farmacológico Púrpura/diagnóstico Púrpura/tratamento farmacológico Síndrome de Sjogren/diagnóstico Síndrome de Sjogren/tratamento farmacológico
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[Mh] Termos MeSH secundário: |
Feminino Seres Humanos Extremidade Inferior Meia-Idade Postura
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[Pt] Tipo de publicação: | CASE REPORTS; JOURNAL ARTICLE |
[Nm] Nome de substância:
| 0 (Antirheumatic Agents); 4QWG6N8QKH (Hydroxychloroquine) |
[Em] Mês de entrada: | 1802 |
[Cu] Atualização por classe: | 180301 |
[Lr] Data última revisão:
| 180301 |
[Sb] Subgrupo de revista: | AIM; IM |
[Da] Data de entrada para processamento: | 180203 |
[St] Status: | MEDLINE |
[do] DOI: | 10.1097/MD.0000000000009187 |
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