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  1 / 4991 MEDLINE  
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[PMID]:29384878
[Au] Autor:Kang S; Gao F; Han J; Mao T; Sun W; Wang B; Guo W; Cheng L; Li Z
[Ad] Endereço:Department of Surgery.
[Ti] Título:Extracorporeal shock wave treatment can normalize painful bone marrow edema in knee osteoarthritis: A comparative historical cohort study.
[So] Source:Medicine (Baltimore);97(5):e9796, 2018 Feb.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Bone marrow edema (BME) represents a reversible but highly painful finding in magnetic resonance imaging (MRI) of patients with knee osteoarthritis. The aim of this retrospective study was to evaluate the efficacy of extracorporeal shock wave treatment (ESWT) on painful BME in osteoarthritis of the knee.This study focuses on people who had early-to-mid stage osteoarthritis with knee pain and MRI findings of BME. Patients who underwent ESWT treatment or prescribed alendronate treatment in our department were analyzed. Knee pain and function were measured using the visual analog scale (VAS) for pain and the Western Ontario and McMaster University Osteoarthritis Index (WOMAC), respectively. The degree of BME was measured with MRI scans.A total of 126 patients who received ESWT treatment (Group A, n = 82) or alendronate treatment (Group B, n = 44) were included. All patients were followed up clinically and radiographically for a minimum of 12 months. The mean follow-up was 23.5 months (range, 12-38 months). The VAS and WOMAC score decreased more significantly after treatment in Group A than that in Group B (P <.01) within 3 months. In 6-month MRI follow-ups, there was higher incidence of distinct reduction and complete regression of BME of the affected knee in Group A than that in Group B (P <.01).ESWT is an effective, reliable, and noninvasive treatment in patients with painful BME in osteoarthritis of the knee followed by a rapid normalization of the MRI appearance. It has the potential to shorten the natural course of this disease.
[Mh] Termos MeSH primário: Doenças da Medula Óssea/terapia
Edema/terapia
Tratamento por Ondas de Choque Extracorpóreas
Osteoartrite do Joelho/complicações
Osteoartrite do Joelho/terapia
[Mh] Termos MeSH secundário: Adulto
Idoso
Doenças da Medula Óssea/diagnóstico por imagem
Doenças da Medula Óssea/etiologia
Edema/diagnóstico por imagem
Edema/etiologia
Feminino
Estudo Historicamente Controlado
Seres Humanos
Imagem por Ressonância Magnética
Masculino
Meia-Idade
Osteoartrite do Joelho/diagnóstico por imagem
Medição da Dor
Estudos Retrospectivos
Resultado do Tratamento
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; OBSERVATIONAL STUDY
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180221
[Lr] Data última revisão:
180221
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180201
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000009796


  2 / 4991 MEDLINE  
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[PMID]:29315006
[Au] Autor:Pountos I; Giannoudis PV
[Ad] Endereço:a Academic Department of Trauma & Orthopaedics, School of Medicine , University of Leeds , Leeds , United Kingdom.
[Ti] Título:The role of Iloprost on bone edema and osteonecrosis: Safety and clinical results.
[So] Source:Expert Opin Drug Saf;17(3):225-233, 2018 Mar.
[Is] ISSN:1744-764X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: Iloprost is a commercially available prostaglandin I (PGI ) analogue that is shown to have antithrombotic, vasodilatative and antiproliferative effects. A number of clinical studies have shown that Iloprost can be effective in the management of bone marrow oedema and the treatment of avascular necrosis. The aim of this manuscript is to present our current understanding on the effect of Iloprost on the treatment of these conditions. Areas covered: The authors offer a comprehensive review of the existing literature on the experimental and clinical studies analysing the effect of Iloprost on bone, bone marrow oedema and avascular necrosis. Expert opinion: The available data from the clinical studies suggest that Iloprost has limited effect in advanced stages of avascular necrosis. However, literature suggests that Iloprost administration can be a viable option in the management of bone marrow oedema and early stages of osteonecrosis. Despite these promising results its effect on bone homeostasis needs further elucidation. Moreover, further data on its safety, dosage and efficiency through randomized multicenter studies are desirable in order to reach final conclusions.
[Mh] Termos MeSH primário: Doenças da Medula Óssea/tratamento farmacológico
Edema/tratamento farmacológico
Iloprosta/uso terapêutico
Osteonecrose/tratamento farmacológico
[Mh] Termos MeSH secundário: Animais
Doenças da Medula Óssea/patologia
Edema/patologia
Seres Humanos
Iloprosta/efeitos adversos
Osteonecrose/patologia
Vasodilatadores/efeitos adversos
Vasodilatadores/uso terapêutico
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Vasodilator Agents); JED5K35YGL (Iloprost)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180215
[Lr] Data última revisão:
180215
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180110
[St] Status:MEDLINE
[do] DOI:10.1080/14740338.2018.1424828


  3 / 4991 MEDLINE  
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[PMID]:29369209
[Au] Autor:Wang Y; Tang XY; Yuan J; Wu SQ; Chen G; Zhang MM; Wang MG; Zhang WY; He JQ
[Ad] Endereço:Department of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, People's Republic of China.
[Ti] Título:Bone marrow granulomas in a high tuberculosis prevalence setting: A clinicopathological study of 110 cases.
[So] Source:Medicine (Baltimore);97(4):e9726, 2018 Jan.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Granulomas were reported in 0.3% to 3% of bone marrow biopsies. The aim of the study was to evaluate the incidence and etiology of bone marrow granulomas (BMGs) in the West China Hospital, which located at a high tuberculosis (TB) prevalence area in China.A retrospective case review was performed on 11,339 bone marrow biopsies at the West China Hospital of Sichuan University between January 2011 and December 2015. Cases with BMGs were retrieved and their clinical data and histopathological features were collected, examined, and analyzed.Out of 11,339, 110 cases showed granulomatous lesions in the bone marrow biopsies (0.97%). Etiologies were indentified in 80 cases (72.8%), with infections being the most common (64.5%), following by malignancies (4.5%) and autoimmune diseases (3.6%). Among infectious cases, 87.32% (62/71) cases were diagnosed as TB, a positive acid-fast stain or/and polymerase chain reaction (PCR) result for mycobacterium TB DNA fragment amplification was obtained for 35 cases. In 30 cases (27.27%), a definite diagnosis could not be established.In a TB high prevalence region in China, with a combined histological, clinical, serological, and molecular approach, we were able to clarify the cause in 72.73% of the bone marrow granulomatous cases. TB is the most common underlying etiologies. Therefore, acid-fast stain and quantitative PCR for mycobacterium TB DNA amplification are recommended as a routine for bone marrow biopsies in TB high prevalence regions.
[Mh] Termos MeSH primário: Doenças da Medula Óssea/etiologia
Granuloma/etiologia
Tuberculose Pulmonar/epidemiologia
[Mh] Termos MeSH secundário: Adulto
Doenças da Medula Óssea/diagnóstico
Doenças da Medula Óssea/epidemiologia
Brucelose/diagnóstico
China/epidemiologia
Diagnóstico Diferencial
Feminino
Granuloma/diagnóstico
Granuloma/epidemiologia
Seres Humanos
Masculino
Meia-Idade
Micoses/diagnóstico
Prevalência
Estudos Retrospectivos
Tuberculose Pulmonar/complicações
[Pt] Tipo de publicação:EVALUATION STUDIES; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180208
[Lr] Data última revisão:
180208
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180126
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000009726


  4 / 4991 MEDLINE  
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[PMID]:29240803
[Au] Autor:Wang D; Hou Z; Gong Y; Chen S; Lin L; Xiao Z
[Ad] Endereço:Department of Rheumatology, the first Affiliated Hospital, Shantou University Medical College, Shantou, Guangdong, China.
[Ti] Título:Bone edema on magnetic resonance imaging is highly associated with low bone mineral density in patients with ankylosing spondylitis.
[So] Source:PLoS One;12(12):e0189569, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: This study aimed to assess the relationship between bone marrow edema (BME) on magnetic resonance imaging (MRI) and bone mineral density (BMD) in patients with ankylosing spondylitis (AS). METHODS: The study included 333 patients with AS who underwent BMD measurements and axial MRI. Additionally, 106 normal controls were included. The modified New York criteria were used as the classification criteria of AS. Clinical, laboratory, and imaging data were collected and analyzed. Lumbar spine and proximal femur BMD were assessed using dual-energy X-ray absorptiometry. Low BMD was defined by a Z-score ≤-2. The Spondyloarthritis Research Consortium of Canada (SPARCC) MRI index was used to assess inflammation at the sacroiliac joint (SIJ) and spine. RESULTS: Among the 333 patients, the male:female ratio was 4.6:1, mean patient age was 28.5±10.6 years, and mean disease duration was 7.3±6.8 years. The prevalences of low BMD, osteopenia, and osteoporosis were significantly higher among AS patients than among controls (19.8%, 62.8%, and 5.7% vs. 4.7%, 33.0%, and 0%, respectively, P = 0.000). The BMD values were significantly lower and prevalences of low BMD at both the spine and femur were significantly higher among patients with BME on MRI than among those without BME. Multivariate logistic regression analysis showed that male sex (OR 3.87, 95% CI 1.21-7.36, P = 0.023), high ASDAS-CRP score (OR 2.83, 95% CI 1.36-4.76, P = 0.015), the presence of BME on sacroiliac MRI (OR 2.83, 95% CI 1.77-6.23, P = 0.000) and spinal MRI (OR 4.06, 95% CI 1.96-8.46, P = 0.000), and high grade of sacroiliitis (OR 2.93, 95% CI 1.82-4.45, P = 0.002) were risk factors for low BMD (any site). The SPARCC scores of the SIJ were negatively correlated with femoral BMD (r = -0.22, 95% CI -0.33 to -0.10, P = 0.000). Additionally, the SPARCC scores of the spine were negatively correlated with BMD values (r = -0.23, 95% CI -0.36 to -0.09, P = 0.003) and Z-scores (r = -0.24, 95% CI -0.36 to -0.12, P = 0.001) at the spine. CONCLUSION: Low BMD is common in AS patients. BME on MRI is highly associated with low BMD at both the spine and femur.
[Mh] Termos MeSH primário: Densidade Óssea
Doenças da Medula Óssea/complicações
Edema/complicações
Imagem por Ressonância Magnética/métodos
Espondilite Anquilosante/diagnóstico por imagem
[Mh] Termos MeSH secundário: Absorciometria de Fóton
Adolescente
Adulto
Estudos de Casos e Controles
Feminino
Seres Humanos
Masculino
Fatores de Risco
Coluna Vertebral/diagnóstico por imagem
Espondilite Anquilosante/complicações
Espondilite Anquilosante/fisiopatologia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171229
[Lr] Data última revisão:
171229
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171215
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0189569


  5 / 4991 MEDLINE  
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[PMID]:29255553
[Au] Autor:Hiddou A; Zemmrani Y; Ahroui Y; Soraa N
[Ad] Endereço:Service de Microbiologie, CHU Mohammed VI, Faculté de Médecine et de Pharmacie, Université Cadi Ayyad, Marrakech, Maroc.
[Ti] Título:[Bacteremia due to Kingella denitrificans in a child followed-up for bone marrow failure syndrome].
[Ti] Título:Bactériémie à Kingella denitrificans chez un enfant suivi pour un syndrome d'insuffisance médullaire..
[So] Source:Pan Afr Med J;28:83, 2017.
[Is] ISSN:1937-8688
[Cp] País de publicação:Uganda
[La] Idioma:fre
[Ab] Resumo:Kingella denitrificans is a non-pathogenic micro-organism present in oropharyngeal flora. This germ has been recently recognized as responsible for opportunistic invasive infections mainly affecting immunosuppressed patients. We here report the case of a child aged 3 years and 7 months followed-up since the age of one year for bone marrow failure syndrome associated with pancytopenia of undetermined origin who had bacteremia due to Kingella denitrificans, a group of difficult to culture gram-negative bacteria rarely described in the literature. Clinicians and microbiologists should suspect the presence of this germ especially in immunosuppressed patients. The use of blood culture bottle contributes in a significant way to the detection of this germ.
[Mh] Termos MeSH primário: Anemia Aplástica/imunologia
Bacteriemia/diagnóstico
Doenças da Medula Óssea/imunologia
Hemoglobinúria Paroxística/imunologia
Infecções por Neisseriaceae/diagnóstico
Infecções Oportunistas/diagnóstico
[Mh] Termos MeSH secundário: Bacteriemia/microbiologia
Pré-Escolar
Seres Humanos
Hospedeiro Imunocomprometido
Kingella/isolamento & purificação
Masculino
Infecções por Neisseriaceae/microbiologia
Infecções Oportunistas/microbiologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171222
[Lr] Data última revisão:
171222
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171220
[St] Status:MEDLINE
[do] DOI:10.11604/pamj.2017.28.83.13698


  6 / 4991 MEDLINE  
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[PMID]:28801981
[Au] Autor:Giri N; Reed HD; Stratton P; Savage SA; Alter BP
[Ad] Endereço:Division of Cancer Epidemiology and Genetics, Clinical Genetics Branch, National Cancer Institute, Rockville, Maryland.
[Ti] Título:Pregnancy outcomes in mothers of offspring with inherited bone marrow failure syndromes.
[So] Source:Pediatr Blood Cancer;65(1), 2018 Jan.
[Is] ISSN:1545-5017
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Children with inherited bone marrow failure syndromes (IBMFSs) may be symptomatic in utero, resulting in maternal and fetal problems during the pregnancy. Subsequent pregnancies by their mothers should be considered "high risk". METHODS: We retrospectively analyzed outcomes of 575 pregnancies in 165 unaffected mothers of offspring with Fanconi anemia (FA), dyskeratosis congenita (DC), Diamond-Blackfan anemia (DBA), and Shwachman-Diamond syndrome (SDS) for events noted during pregnancy, labor, and delivery. We compared outcomes of pregnancies with affected and unaffected offspring within each group of mothers and with the general population. RESULTS: The rates of miscarriage (12-20%), elective abortion (5-10%), and live birth (68-78%) among mothers of all IBMFS groups were similar and comparable with general population rates but recurrent miscarriages (≥2) were significantly more common in mothers of offspring with DBA and SDS. Offspring with FA were more frequently born small for gestational age (SGA) than unaffected babies (39% vs. 4%) and had fetal malformations (46%) with 18% having three or more, often necessitating early delivery and surgery; offspring with DC had higher rates of SGA (39% vs. 8%) and fetal distress (26% vs. 3%); and offspring with DBA had fetal hypoxia (19% vs. 1%) leading to preterm and emergency cesarean deliveries (26% vs. 6%). Offspring with early-onset severe phenotypes had the most prenatal and peripartum adverse events. CONCLUSION: We identified the high-risk nature of pregnancies in mothers with IBMFS-affected fetuses, suggesting the need for prepregnancy counseling and monitoring of subsequent pregnancies by high-risk fetal-maternal specialists.
[Mh] Termos MeSH primário: Aborto Espontâneo
Anemia Aplástica
Doenças da Medula Óssea
Hemoglobinúria Paroxística
Recém-Nascido Pequeno para a Idade Gestacional
Nascimento Vivo
Período Periparto
Nascimento Prematuro/epidemiologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Feminino
Seres Humanos
Recém-Nascido
Meia-Idade
Gravidez
[Pt] Tipo de publicação:CLINICAL TRIAL; COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171129
[Lr] Data última revisão:
171129
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170813
[St] Status:MEDLINE
[do] DOI:10.1002/pbc.26757


  7 / 4991 MEDLINE  
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[PMID]:28708320
[Au] Autor:Pezeshki A; Podder S; Kamel R; Corey SJ
[Ad] Endereço:Wayne State University School of Medicine, Detroit, Michigan.
[Ti] Título:Monosomy 7/del (7q) in inherited bone marrow failure syndromes: A systematic review.
[So] Source:Pediatr Blood Cancer;64(12), 2017 Dec.
[Is] ISSN:1545-5017
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Inherited bone marrow failure syndromes (IBMFS) are rare cancer predisposition syndromes with an especially high risk of transformation to myelodysplastic syndrome (MDS) and/or acute myeloid leukemia (AML). We performed a retrospective systematic review of reported MDS/AML arising in the eight most common IBMFS to determine the frequency and outcome of chromosome 7 abnormalities. We identified 738 MDS/AML cases of 4,293 individuals. Monosomy 7 or del (7q) occurred in ∼17%. Greater understanding of the roles played by sequential acquisition of genetic and cytogenetic changes will provide insights into myeloid leukemogenesis and improve the surveillance and hopefully outcomes for individuals with IBMFS.
[Mh] Termos MeSH primário: Anemia Aplástica/genética
Doenças da Medula Óssea/genética
Deleção Cromossômica
Hemoglobinúria Paroxística/genética
[Mh] Termos MeSH secundário: Adolescente
Adulto
Criança
Pré-Escolar
Cromossomos Humanos Par 7
Seres Humanos
Lactente
Recém-Nascido
Estudos Retrospectivos
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171026
[Lr] Data última revisão:
171026
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170715
[St] Status:MEDLINE
[do] DOI:10.1002/pbc.26714


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[PMID]:28679999
[Au] Autor:Ito M
[Ad] Endereço:Department of Pathology, Japanese Red Cross Nagoya First Hospital.
[Ti] Título:Bone marrow failure in childhood: central pathology review of a nationwide registry.
[So] Source:Rinsho Ketsueki;58(6):661-668, 2017.
[Is] ISSN:0485-1439
[Cp] País de publicação:Japan
[La] Idioma:jpn
[Ab] Resumo:Refractory cytopenia of childhood (RCC) was proposed as a provisional entity in the 2008 WHO classification of myelodysplastic syndromes (MDS). It is defined as a childhood MDS featuring persistent cytopenia without increase blasts in bone marrow (BM) or peripheral blood (PB). Because the majority of RCC cases feature hypocellularity and pancytopenia, it is quite challenging to differentiate RCC from acquired aplastic anemia (AA) and many kinds of inherited bone marrow failure syndromes (IBMFS). Diagnosis of RCC requires BM histology of characteristic features such as isolated erythroid islet with left shift, abnormal localization and micromegakaryocytes. The Japanese Society of Pediatric Hematology/Oncology has opened the central registry review system since 2009 to evaluate childhood cases of bone marrow failure (BMF). It has reviewed cytology and BM pathology of all registered BMF cases, which number more than 1,700. In the evaluation of BMF, BM pathology is important to assess the mechanism of hematopoiesis. Pathological dysplasia should be differentiated from cytological dysplasia. A central review system is important for rare diseases, such as pediatric BMF. Standardization of pathological diagnosis should be established upon consensus findings, descriptions, and diagnostic approaches. In this review, the pathology of pediatric BMF syndromes is summarized.
[Mh] Termos MeSH primário: Doenças da Medula Óssea/patologia
Medula Óssea/patologia
[Mh] Termos MeSH secundário: Doenças da Medula Óssea/diagnóstico
Doenças da Medula Óssea/epidemiologia
Morte Celular
Criança
Progressão da Doença
Eritrócitos/patologia
Seres Humanos
Sistema de Registros
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171102
[Lr] Data última revisão:
171102
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170707
[St] Status:MEDLINE
[do] DOI:10.11406/rinketsu.58.661


  9 / 4991 MEDLINE  
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[PMID]:28678969
[Au] Autor:Braga-Diniz JM; Santa-Rosa CC; Martins RC; Silva MESE; Vieira LQ; Ribeiro Sobrinho AP
[Ad] Endereço:Universidade Federal de Minas Gerais - UFMG, School of Dentistry, Departament of Operative Dentistry, Belo Horizonte, MG, Brazil.
[Ti] Título:The need for endodontic treatment and systemic characteristics of hematopoietic stem cell transplantation patients.
[So] Source:Braz Oral Res;31:e50, 2017 Jul 03.
[Is] ISSN:1807-3107
[Cp] País de publicação:Brazil
[La] Idioma:eng
[Ab] Resumo:The aim of this study is to investigate the relationship between the epidemiological and clinical profiles of patients before and after hematopoietic stem cell transplantation (HSCT) and the need for endodontic treatment. The subjects included 188 individuals enrolled in the dental care program for transplanted patients of the School of Dentistry, Federal University of Minas Gerais (Faculdade de Odontologia da Universidade Federal de Minas Gerais, FO-UFMG) from March 2011 through March 2016. The patients were subjected to an HSCT conditioning dental regimen based on a thorough clinical and radiographic evaluation. Intraoral periapical and bite-wing X-rays were obtained, and after evaluation, specific dental treatment was planned and performed. The following demographic and clinical data were collected from the patients' medical records: age, gender, transplantation stage, primary disease, transplant type, medication used, complete blood count at the time of visit, and need for endodontic treatment. The Kolmogorov-Smirnov and the chi-square tests were used. Leukemia (31.3%) and multiple myeloma (17.9%) were the most prevalent primary diseases. Most patients were subjected to allogeneic-related transplantation (83.6%). Most patients exhibited platelet counts and hemoglobin concentrations below the reference values in the pre-transplantation stage, while the neutrophil and platelet counts and the hemoglobin levels were within the reference ranges in the post-transplantation stage. The proportions of individuals requiring endodontic treatment were similar between the pre- and post-transplantation groups: 24.3% and 24.7%, respectively. The systemic conditions of the patients referred for dental treatment were compromised.
[Mh] Termos MeSH primário: Assistência Odontológica para Doentes Crônicos/estatística & dados numéricos
Transplante de Células-Tronco Hematopoéticas/efeitos adversos
Transplante de Células-Tronco Hematopoéticas/estatística & dados numéricos
Determinação de Necessidades de Cuidados de Saúde/estatística & dados numéricos
Tratamento do Canal Radicular/estatística & dados numéricos
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Contagem de Células Sanguíneas
Doenças da Medula Óssea/imunologia
Doenças da Medula Óssea/cirurgia
Criança
Feminino
Seres Humanos
Imunossupressão/efeitos adversos
Leucemia/imunologia
Leucemia/cirurgia
Linfoma/imunologia
Linfoma/cirurgia
Masculino
Meia-Idade
Mieloma Múltiplo/imunologia
Mieloma Múltiplo/cirurgia
Fatores de Risco
Estatísticas não Paramétricas
Transplante Homólogo/efeitos adversos
Transplante Homólogo/estatística & dados numéricos
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170822
[Lr] Data última revisão:
170822
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:170706
[St] Status:MEDLINE


  10 / 4991 MEDLINE  
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[PMID]:28656955
[Au] Autor:Fetisov VA; Kulinkovich KY
[Ad] Endereço:Federal state budgetary institution 'Russian Federal Centre of Forensic Medical Expertise', Ministry of Health of the Russia, Moscow, Russia, 125284.
[Ti] Título:[MRI diagnostics of bone marrow oedema and its significance for the forensic medical evaluation of the injuries to bones and articulations].
[Ti] Título:MRT-diagnostika oteka kostnogo mozga i ego znachenie v sudebno-meditsinskoi otsenke povrezhdenii kostei i sustavov..
[So] Source:Sud Med Ekspert;60(3):50-56, 2017.
[Is] ISSN:0039-4521
[Cp] País de publicação:Russia (Federation)
[La] Idioma:rus
[Ab] Resumo:The objective of the present study was the analysis of the publications in the literature dealing with radiological methods employed for the diagnostics of injuries to and diseases of the bones and articulations as well as the role of bone marrow oedema in the development of these conditions in the specific context of the problems facing forensic medical expertise. The main results of the domestic and foreign authors concerning MRI-based investigations into the nature of injuries and other pathological changes in bones and articulations during different periods after their development are discussed with the major emphasis placed on diagnostics of bone marrow oedema. Magnetic resonance visualization of this diagnostic feature and the related manifestations of the above conditions in many cases provides an indisputable evidence of the damage whereas the discovery of its distribution to and localization in the bone structures makes it possible to elucidate the sources of this condition, such as a blow, torsional stress, stretching, etc., and its underlying mechanisms. The character and the mode of distribution of the signal from a bone marrow oedema under various conditions of visualization allow to carry out differential diagnostics of the damage prescription period of up to 1.5 months.
[Mh] Termos MeSH primário: Doenças da Medula Óssea
Medula Óssea
Fraturas Ósseas/complicações
Articulações/lesões
Imagem por Ressonância Magnética/métodos
[Mh] Termos MeSH secundário: Medula Óssea/diagnóstico por imagem
Medula Óssea/patologia
Doenças da Medula Óssea/etiologia
Doenças da Medula Óssea/patologia
Edema
Patologia Legal/métodos
Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170831
[Lr] Data última revisão:
170831
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170629
[St] Status:MEDLINE
[do] DOI:10.17116/sudmed201760350-56



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