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[PMID]:29371179
[Au] Autor:Chin X; Chan DKL; Chong JH
[Ad] Endereço:KK Women's and Children's Hospital, Singapore chin.xinyi@singhealth.com.sg.
[Ti] Título:A rash that's more than skin deep.
[So] Source:BMJ;360:k8, 2018 01 25.
[Is] ISSN:1756-1833
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Exantema/diagnóstico
Dermatoses Faciais/diagnóstico
Lúpus Eritematoso Sistêmico/congênito
Púrpura/diagnóstico
[Mh] Termos MeSH secundário: Diagnóstico Diferencial
Exantema/congênito
Dermatoses Faciais/congênito
Feminino
Seres Humanos
Lactente
Lúpus Eritematoso Sistêmico/complicações
Lúpus Eritematoso Sistêmico/diagnóstico
Púrpura/congênito
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180306
[Lr] Data última revisão:
180306
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180127
[St] Status:MEDLINE
[do] DOI:10.1136/bmj.k8


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[PMID]:29390528
[Au] Autor:Xu X; Zheng Y; Zhao Z; Zhang X; Liu P; Li C
[Ad] Endereço:Department of Dermatology.
[Ti] Título:Efficacy of photodynamic therapy combined with minocycline for treatment of moderate to severe facial acne vulgaris and influence on quality of life.
[So] Source:Medicine (Baltimore);96(51):e9366, 2017 Dec.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Acne vulgaris is a prevalent skin disorder impairing both physical and psychosocial health. This study was designed to investigate the effectiveness of photodynamic therapy (PDT) combined with minocycline in moderate to severe facial acne and influence on quality of life (QOL). METHODS: Ninety-five patients with moderate to severe facial acne (Investigator Global Assessment [IGA] score 3-4) were randomly treated with PDT and minocycline (n = 48) or minocycline alone (n = 47). All patients took minocycline hydrochloride 100 mg/d for 4 weeks, whereas patients in the minocycline plus PDT group also received 4 times PDT treatment 1 week apart. IGA score, lesion counts, Dermatology Life Quality Index (DLQI), and safety evaluation were performed before treatment and at 2, 4, 6, and 8 weeks after enrolment. RESULTS: There were no statistically significant differences in characteristics between 2 treatment groups at baseline. Minocycline plus PDT treatment led to a greater mean percentage reduction from baseline in lesion counts versus minocycline alone at 8 weeks for both inflammatory (-74.4% vs -53.3%; P < .001) and noninflammatory lesions (-61.7% vs -42.4%; P < .001). More patients treated with minocycline plus PDT achieved IGA score <2 at study end (week 8: 30/48 vs 20/47; P < .05). Patients treated with minocycline plus PDT got significant lower DLQI at 8 weeks (4.4 vs 6.3; P < .001). Adverse events were mild and manageable. CONCLUSIONS: Compared with minocycline alone, the combination of PDT with minocycline significantly improved clinical efficacy and QOL in moderate to severe facial acne patients.
[Mh] Termos MeSH primário: Acne Vulgar/tratamento farmacológico
Minociclina/uso terapêutico
Fotoquimioterapia/métodos
Qualidade de Vida
[Mh] Termos MeSH secundário: Acne Vulgar/diagnóstico
Acne Vulgar/psicologia
Adolescente
Adulto
Distribuição de Qui-Quadrado
Terapia Combinada
Dermatoses Faciais/diagnóstico
Dermatoses Faciais/tratamento farmacológico
Feminino
Seguimentos
Seres Humanos
Masculino
Estudos Prospectivos
Índice de Gravidade de Doença
Resultado do Tratamento
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
FYY3R43WGO (Minocycline)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180219
[Lr] Data última revisão:
180219
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180203
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000009366


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[PMID]:27775976
[Au] Autor:Grey KR; Warshaw EM
[Ad] Endereço:From the *University of Minnesota Medical School; †HCMC Parkside Occupational and Contact Dermatitis Clinic; ‡Department of Dermatology, Minneapolis Veterans Affairs Medical Center; and §Department of Dermatology, University of Minnesota Medical School, Minneapolis.
[Ti] Título:Allergic Contact Dermatitis to Ophthalmic Medications: Relevant Allergens and Alternative Testing Methods.
[So] Source:Dermatitis;27(6):333-347, 2016 Nov/Dec.
[Is] ISSN:2162-5220
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Allergic contact dermatitis is an important cause of periorbital dermatitis. Topical ophthalmic agents are relevant sensitizers. Contact dermatitis to ophthalmic medications can be challenging to diagnose and manage given the numerous possible offending agents, including both active and inactive ingredients. Furthermore, a substantial body of literature reports false-negative patch test results to ophthalmic agents. Subsequently, numerous alternative testing methods have been described. This review outlines the periorbital manifestations, causative agents, and alternative testing methods of allergic contact dermatitis to ophthalmic medications.
[Mh] Termos MeSH primário: Dermatite Alérgica de Contato/etiologia
Dermatoses Faciais/etiologia
Lubrificantes Oftálmicos/efeitos adversos
Soluções Oftálmicas/efeitos adversos
[Mh] Termos MeSH secundário: Administração Oftálmica
Agonistas de Receptores Adrenérgicos alfa 1/efeitos adversos
Antagonistas Adrenérgicos beta/efeitos adversos
Antibacterianos/efeitos adversos
Anti-Infecciosos Locais/efeitos adversos
Anti-Inflamatórios/efeitos adversos
Antineoplásicos/efeitos adversos
Antivirais/efeitos adversos
Inibidores da Anidrase Carbônica/efeitos adversos
Antagonistas Colinérgicos/efeitos adversos
Glaucoma/tratamento farmacológico
Antagonistas dos Receptores Histamínicos/efeitos adversos
Seres Humanos
Agonistas Muscarínicos/efeitos adversos
Antagonistas Muscarínicos/efeitos adversos
Prostaglandinas Sintéticas/efeitos adversos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Adrenergic alpha-1 Receptor Agonists); 0 (Adrenergic beta-Antagonists); 0 (Anti-Bacterial Agents); 0 (Anti-Infective Agents, Local); 0 (Anti-Inflammatory Agents); 0 (Antineoplastic Agents); 0 (Antiviral Agents); 0 (Carbonic Anhydrase Inhibitors); 0 (Cholinergic Antagonists); 0 (Histamine Antagonists); 0 (Lubricant Eye Drops); 0 (Muscarinic Agonists); 0 (Muscarinic Antagonists); 0 (Ophthalmic Solutions); 0 (Prostaglandins, Synthetic)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180212
[Lr] Data última revisão:
180212
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161025
[St] Status:MEDLINE


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[PMID]:28468200
[Au] Autor:Ata N; Gögüs HE; Kiliç S
[Ad] Endereço:*Department of Otorhinolaryngology, Gaziantep 25 Aralik State Hospital, Gaziantep †National Tularemia Reference Laboratory, Public Health Institution of Turkey, Ankara, Turkey.
[Ti] Título:Giant Orf on the Nose.
[So] Source:J Craniofac Surg;28(3):e234-e235, 2017 May.
[Is] ISSN:1536-3732
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Orf is a zoonotic infectious disease caused by parapoxvirus. Orf lesions are typically seen on the hand, but they have rarely been reported on the nose. Herein, the authors report a rare patient of an orf lesion on the nose of a 52-year-old man after the Muslim celebration of the feast of the sacrifice. The lesion spontaneously recovered 8 weeks after the initial appearance and showed no evidence of recurrence after 1 year of follow-up. Orf virus infections may occur more often after the celebration of the feast of the sacrifice in Muslim countries.
[Mh] Termos MeSH primário: Ectima Contagioso/diagnóstico
Dermatoses Faciais/patologia
Dermatoses Faciais/virologia
Doenças Nasais/patologia
Doenças Nasais/virologia
[Mh] Termos MeSH secundário: Ectima Contagioso/etiologia
Ectima Contagioso/terapia
Dermatoses Faciais/terapia
Seres Humanos
Masculino
Meia-Idade
Doenças Nasais/terapia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180205
[Lr] Data última revisão:
180205
[Sb] Subgrupo de revista:D
[Da] Data de entrada para processamento:170505
[St] Status:MEDLINE
[do] DOI:10.1097/SCS.0000000000003441


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[PMID]:29186262
[Au] Autor:António AM; Alves JV; Coelho R; Bártolo E
[Ad] Endereço:Dermatovenereology Service, Hospital Garcia de Orta - Almada, Portugal.
[Ti] Título:Solitary ulcerated plaque on the face - an unusual presentation of cutaneous plasmacytosis?
[So] Source:An Bras Dermatol;92(3):410-412, 2017 May-Jun.
[Is] ISSN:1806-4841
[Cp] País de publicação:Brazil
[La] Idioma:eng
[Ab] Resumo:Cutaneous and systemic plasmacytosis is a rare disorder characterized by cutaneous polyclonal plasma cell infiltration frequently associated with polyclonal hypergammaglobulinemia and lymphadenopathy. We report a case of a 67-year-old woman with an inflammatory ulcerated plaque in the left masseter region. A skin biopsy showed dense perivascular infiltrate of mature plasma cells in the dermis without atypia and immunoglobulin light chain restriction. After physical examination and further investigation, we ruled out systemic disease. Our patient was successfully treated only with hydrocortisone cream application. Few cases of isolated benign primary cutaneous plasmacytosis have been described, particularly in children. After excluding the diagnosis of a reactive process to an infection, which is unlikely in this case, we suspected of a rare manifestation of primary cutaneous plasmacytosis in adults with distinct presentation and clinical course.
[Mh] Termos MeSH primário: Dermatoses Faciais/patologia
Plasmócitos/patologia
[Mh] Termos MeSH secundário: Idoso
Feminino
Seres Humanos
[Pt] Tipo de publicação:CASE REPORTS
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180131
[Lr] Data última revisão:
180131
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171130
[St] Status:MEDLINE


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[PMID]:29281582
[Au] Autor:Si Z; Qiao J
[Ad] Endereço:Beilun People's Hospital, Ningbo, China.
[Ti] Título:Talaromyces marneffei Infection.
[So] Source:N Engl J Med;377(26):2580, 2017 12 28.
[Is] ISSN:1533-4406
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Infecções Oportunistas Relacionadas com a AIDS/patologia
Dermatoses Faciais/patologia
Micoses/patologia
Talaromyces/isolamento & purificação
[Mh] Termos MeSH secundário: Infecções Oportunistas Relacionadas com a AIDS/microbiologia
Adulto
Doenças Endêmicas
Dermatoses Faciais/microbiologia
Soropositividade para HIV/complicações
Seres Humanos
Masculino
Micoses/microbiologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180115
[Lr] Data última revisão:
180115
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171228
[St] Status:MEDLINE
[do] DOI:10.1056/NEJMicm1704164


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[PMID]:28984765
[Au] Autor:Liu KL; Tsai WC; Lee CH
[Ad] Endereço:Department of Dermatology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
[Ti] Título:Cutaneous sarcoidosis: A retrospective case series and a hospital-based case-control study in Taiwan.
[So] Source:Medicine (Baltimore);96(40):e8158, 2017 Oct.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Sarcoidosis is a systemic granulomatous disorder of unknown etiology often involving skin. Studies on cutaneous sarcoidosis and comorbidities are limited. This study is aimed to describe the clinical features of cutaneous sarcoidosis diagnosed in our hospital and to determine the relationships between cutaneous sarcoidosis and comorbidities.This retrospective study evaluates patients with cutaneous sarcoidosis in a tertiary center in Taiwan from 1996 to 2015. The records of 38 patients with cutaneous sarcoidosis were reviewed for clinical characteristics and evaluated by analysis of variance. A 1:4 case-control analysis was conducted with 152 age- and sex-matched controls who underwent biopsy for other benign skin tumors.The male to female ratio was 1:4.4. The average age at diagnosis was 51.7 years. Female patients were on average 13.9 years older than male patients. The correlation of age with gender was statistically significant (P = .037). The most common cutaneous lesions were plaques (47.4%) and confined to the face (71.1%). Of the 38 patients, 26.3% had diabetes mellitus. Age over 40 (P = .014) and female (P = .014) were associated with facial involvement. In the case-control study, a higher percentage of patients with cutaneous sarcoidosis than of control subjects had diabetes mellitus (P = .001), hearing loss (P = .031) and eye diseases (P = .047).The present study demonstrates a striking female predominance and high proportions of facial involvement. Diabetes mellitus, hearing loss, and eye diseases may be associated with Taiwanese patients with cutaneous sarcoidosis.
[Mh] Termos MeSH primário: Sarcoidose/complicações
Dermatopatias/patologia
Neoplasias Cutâneas/patologia
[Mh] Termos MeSH secundário: Fatores Etários
Idade de Início
Biópsia
Estudos de Casos e Controles
Face/patologia
Dermatoses Faciais/etiologia
Dermatoses Faciais/patologia
Feminino
Seres Humanos
Masculino
Meia-Idade
Estudos Retrospectivos
Fatores de Risco
Sarcoidose/patologia
Fatores Sexuais
Pele/patologia
Dermatopatias/etiologia
Neoplasias Cutâneas/etiologia
Taiwan
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171012
[Lr] Data última revisão:
171012
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171007
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000008158


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[PMID]:28813557
[Au] Autor:Mervak JE; Gan SD; Smith EH; Wang F
[Ad] Endereço:Department of Dermatology, University of Michigan Medical School, Ann Arbor.
[Ti] Título:Facial Erosive Pustular Dermatosis After Cosmetic Resurfacing.
[So] Source:JAMA Dermatol;153(10):1021-1025, 2017 Oct 01.
[Is] ISSN:2168-6084
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Importance: Erosive pustular dermatosis (EPD) is a rare condition that typically affects actinically damaged skin of the scalp. Characterized by sterile pustules, erosions, and crusts, EPD is difficult to treat and heals slowly. The exact cause of EPD is unknown, although trauma is an inciting factor. Objective: To describe 3 women who presented with prolonged facial erosions after cosmetic resurfacing procedures, specifically fully ablative carbon dioxide laser or medium-depth chemical peel. Design, Setting, and Participants: This case series describes the clinical features, histopathological findings, laboratory results, and treatment of 3 patients with an ultimate diagnosis most consistent with facial EPD. Patients were evaluated between September 10, 2010, and May 6, 2016, in a dermatology clinic in an academic medical center. The patients were 3 women seeking diagnostic evaluation and therapeutic options for nonhealing facial erosions occurring after ablative procedures (carbon dioxide laser resurfacing or Jessner solution/trichloroacetic acid chemical peel). Main Outcomes and Measures: Histologic examination and wound culture from initial presentation as well as clinical follow-up documenting improvement with therapeutic interventions. Results: All 3 patients were women in their 50s or 60s for whom EPD was deemed to be the best diagnosis, after infection, immunobullous disorders, and other pustular dermatoses were considered. Histologic features were nonspecific. Treatment included a combination of topical and systemic therapies, such as corticosteroids, dapsone, isotretinoin, and/or antibiotics. Watchful waiting (tincture of time) appeared to be central to the healing process. Conclusions and Relevance: After cosmetic resurfacing, patients may develop EPD isolated to the face. As a diagnosis of exclusion that should be considered in patients who have nonhealing wounds following ablative procedures, EPD is challenging to treat and may require the use of anti-inflammatory agents. Recognizing this condition is important, especially as cosmetic procedures become more widespread.
[Mh] Termos MeSH primário: Abrasão Química/métodos
Dermatoses Faciais/terapia
Lasers de Gás/uso terapêutico
Dermatopatias Vesiculobolhosas/terapia
[Mh] Termos MeSH secundário: Terapia Combinada
Dermatoses Faciais/patologia
Feminino
Seres Humanos
Meia-Idade
Dermatopatias Vesiculobolhosas/patologia
Resultado do Tratamento
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171023
[Lr] Data última revisão:
171023
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170817
[St] Status:MEDLINE
[do] DOI:10.1001/jamadermatol.2017.2880


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[PMID]:28807114
[Au] Autor:Belum VR; Marchetti MA; Dusza SW; Cercek A; Kemeny NE; Lacouture ME
[Ad] Endereço:Dermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
[Ti] Título:A prospective, randomized, double-blinded, split-face/chest study of prophylactic topical dapsone 5% gel versus moisturizer for the prevention of cetuximab-induced acneiform rash.
[So] Source:J Am Acad Dermatol;77(3):577-579, 2017 09.
[Is] ISSN:1097-6787
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Erupções Acneiformes/prevenção & controle
Anti-Infecciosos/uso terapêutico
Antineoplásicos/efeitos adversos
Carcinoma de Células Escamosas/tratamento farmacológico
Cetuximab/efeitos adversos
Neoplasias Colorretais/tratamento farmacológico
Dapsona/uso terapêutico
Erupção por Droga/prevenção & controle
[Mh] Termos MeSH secundário: Erupções Acneiformes/induzido quimicamente
Adulto
Idoso
Carcinoma de Células Escamosas/secundário
Neoplasias Colorretais/patologia
Método Duplo-Cego
Erupção por Droga/etiologia
Dermatoses Faciais/induzido quimicamente
Dermatoses Faciais/prevenção & controle
Géis
Seres Humanos
Masculino
Meia-Idade
Estudos Prospectivos
Qualidade de Vida
Creme para a Pele/uso terapêutico
Tórax
[Pt] Tipo de publicação:COMPARATIVE STUDY; LETTER; RANDOMIZED CONTROLLED TRIAL; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Anti-Infective Agents); 0 (Antineoplastic Agents); 0 (Gels); 8W5C518302 (Dapsone); PQX0D8J21J (Cetuximab)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170918
[Lr] Data última revisão:
170918
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170816
[St] Status:MEDLINE


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[PMID]:28659135
[Au] Autor:Zhang B; Pan F; Zhu K
[Ad] Endereço:Department of Ophthalmology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, 3 Qinchun Road East, Hangzhou, 310016, Zhejiang, People's Republic of China. zhangbei@srrsh.com.
[Ti] Título:Bilateral Morganella Morganii keratitis in a patient with facial topical corticosteroid-induced rosacea-like dermatitis: a case report.
[So] Source:BMC Ophthalmol;17(1):106, 2017 Jun 28.
[Is] ISSN:1471-2415
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Bilateral keratitis rarely occurs in individuals without predisposing factors. Here we describe the clinical course of a patient who developed a bilateral keratitis caused by Morganella. morganii which might be associated with long term using of topical corticosteroids-containing preparations on the face. CASE PRESENTATION: A 52-year-old female patient presented with marked bilateral corneal infiltration and hypopyon without any usual predisposing factors for bilateral infectious keratitis. There was diffuse erythema with itching on face before the onset of eye discomforts. Microbiological culture of materials from both corneas revealed significant growth of Morganella morganii. Topical corticosteroid-induced rosacea-like dermatitis was diagnosed by dermatologist because of the characteristic eruptions and long history of using the corticosteroids-containing cosmetic creams on her face. The corneal ulcers responded well to levofloxacin eye drops and ofloxacin ointment and healed with opacity and neovascularization. CONCLUSION: This case illustrates that bilateral bacterial corneal infection can develop in patients with long term using of topical corticosteroids-containing preparations on the face. To our knowledge, this is the first case of bilateral keratitis caused by Morganella morganii.
[Mh] Termos MeSH primário: Infecções por Enterobacteriaceae/microbiologia
Infecções Oculares Bacterianas/microbiologia
Dermatoses Faciais/induzido quimicamente
Glucocorticoides/efeitos adversos
Ceratite/microbiologia
Morganella morganii/isolamento & purificação
Rosácea/induzido quimicamente
[Mh] Termos MeSH secundário: Córnea/microbiologia
Córnea/patologia
Diagnóstico Diferencial
Infecções por Enterobacteriaceae/complicações
Infecções por Enterobacteriaceae/diagnóstico
Infecções Oculares Bacterianas/complicações
Infecções Oculares Bacterianas/diagnóstico
Dermatoses Faciais/diagnóstico
Feminino
Seres Humanos
Ceratite/complicações
Ceratite/diagnóstico
Meia-Idade
Rosácea/complicações
Rosácea/diagnóstico
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Glucocorticoids)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171004
[Lr] Data última revisão:
171004
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170630
[St] Status:MEDLINE
[do] DOI:10.1186/s12886-017-0504-5



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