Base de dados : MEDLINE
Pesquisa : C17.800.621.430.530.550 [Categoria DeCS]
Referências encontradas : 1063 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 107 ir para página                         

  1 / 1063 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29272850
[Au] Autor:Togsverd-Bo K; Philipsen PA; Hædersdal M; Wulf HCO
[Ad] Endereço:Department of Dermato-venerology, Bispebjerg University Hospital, 2400 Copenhagen, Denmark. Electronic address: ktogsverdbo@dadlnet.dk.
[Ti] Título:Skin autofluorescence reflects individual seasonal UV exposure, skin photodamage and skin cancer development in organ transplant recipients.
[So] Source:J Photochem Photobiol B;178:577-583, 2018 Jan.
[Is] ISSN:1873-2682
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:IMPORTANCE: Ultraviolet radiation (UVR)-induced skin cancers varies among organ transplant recipients (OTRs). To improve individual risk assessment of skin cancer, objectively quantified skin photodamage is needed. OBJECTIVES: We measured personal UVR-exposure dose in OTRs and assessed the relation between individual UVR exposure, skin cancer and objectively measured photodamage in terms of skin autofluorescence, pigmentation, and black light-evaluated solar lentigines. MATERIALS AND METHODS: Danish OTRs with (n=15) and without a history of skin cancer (n=15) kept sun diaries from May to September and wore personal dosimeters recording time-stamped UVR doses in standard erythema doses (SED). Photodamage was quantified as skin autofluorescence with excitation at 370nm (F370) and 430nm (F430), skin pigmentation (pigment protection factor, PPF), and black light-evaluated solar lentigines. RESULTS: OTRs with skin cancer received a higher UVR dose than OTRs without skin cancer (median 116 SED vs. 67 SED, p=0.07) and UVR exposure doses were correlated with increased PPF (p=0.052) and F370 on the shoulder (F370 ) (p=0.04). We found that skin cancer was associated with F370 (OR 10.53, CI 3.3-31,938; p=0.018) and time since transplantation (OR 1.34, CI 0.95-1.91, p=0.097). A cut-off at 7.2 arbitrary units, 89% of OTRs with skin cancer had F370 values above 7.2 arbitrary units and F370 was additionally related to patient age (p=0.09) and black light-evaluated solar lentigines (p=0.04). CONCLUSION: F370 autofluorescence indicates objectively measured photodamage and may be used for individual risk assessment of skin cancer development in OTRs.
[Mh] Termos MeSH primário: Neoplasias Cutâneas/etiologia
Pele/efeitos da radiação
Raios Ultravioleta
[Mh] Termos MeSH secundário: Adulto
Idoso
Feminino
Seres Humanos
Lentigo/etiologia
Medições Luminescentes
Masculino
Meia-Idade
Razão de Chances
Transplante de Órgãos
Estações do Ano
Pele/química
Pigmentação da Pele/efeitos da radiação
Transplantados
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180212
[Lr] Data última revisão:
180212
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171223
[St] Status:MEDLINE


  2 / 1063 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28676327
[Au] Autor:Kim NH; Choi YD; Seon HJ; Lee JB; Yun SJ
[Ad] Endereço:Department of Dermatology, Chonnam National University Medical School, Gwangju, Korea.
[Ti] Título:Anatomic mapping and clinicopathologic analysis of benign acral melanocytic neoplasms: A comparison between adults and children.
[So] Source:J Am Acad Dermatol;77(4):735-745, 2017 Oct.
[Is] ISSN:1097-6787
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The clinicopathologic features of benign acral melanocytic neoplasms (BAMNs) remain poorly understood. OBJECTIVE: To define the clinicopathologic features of BAMNs. METHODS: We analyzed clinical data and mapped BAMNs anatomically. We also reviewed the histopathologic features of BAMNs and compared these between adults and children. RESULTS: We included 396 cases of BAMN: 335 adults and 61 children (376 acquired and 20 congenital lesions). Anatomic mapping revealed that the nonweight-bearing portion of the foot was the most common site in adults (120/335, 35.8%) and the forefoot the most common site in children (17/61, 27.9%) for BAMNs. The long axes of the BAMNs paralleled the dermatoglyphic lines on the palms and soles, as did most tissue sections. The lesion diameters were <5.7 mm in all acquired lesions. Histopathologically, we diagnosed 69 lentigo simplex, 201 junctional, 114 compound, 8 intradermal, and 4 blue nevi. Corneal pigmentation, nests located between rete ridges, dendrite prominence, and cytologic atypia were all significantly more common in children than adults. LIMITATIONS: The retrospective study design and acquiring patients from a single institution of a single country limited the research results. CONCLUSION: BAMNs develop most commonly on nonweight-bearing regions of the soles in adults and on the forefoot in children. The long axis of the lesion follows the dermatoglyphics, and cytologic atypia is more common in children.
[Mh] Termos MeSH primário: /patologia
Mãos/patologia
Lentigo/patologia
Nevo Pigmentado/patologia
Neoplasias Cutâneas/patologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Fatores Etários
Idoso
Idoso de 80 Anos ou mais
Pontos de Referência Anatômicos
Criança
Pré-Escolar
Feminino
Seres Humanos
Lactente
Recém-Nascido
Masculino
Meia-Idade
Estudos Retrospectivos
Carga Tumoral
Adulto Jovem
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170927
[Lr] Data última revisão:
170927
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170706
[St] Status:MEDLINE


  3 / 1063 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28504388
[Au] Autor:Swetter SM
[Ad] Endereço:Department of Dermatology, Pigmented Lesion and Melanoma Program, Stanford University Medical Center and Cancer Institute, 900 Blake Wilbur Drive, W3045, Stanford, CA, 94028, U.S.A.
[Ti] Título:Challenges of treating melanoma in situ, lentigo maligna type: is pathological clearance the gold standard?
[So] Source:Br J Dermatol;176(5):1115-1116, 2017 05.
[Is] ISSN:1365-2133
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Sarda Melanótica de Hutchinson
Melanoma
[Mh] Termos MeSH secundário: Seres Humanos
Lentigo
Neoplasias Cutâneas
[Pt] Tipo de publicação:JOURNAL ARTICLE; COMMENT
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171107
[Lr] Data última revisão:
171107
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170516
[St] Status:MEDLINE
[do] DOI:10.1111/bjd.15512


  4 / 1063 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28369728
[Au] Autor:Maher NG; Guitera P
[Ad] Endereço:Melanoma Institute Australia, Sydney, Australia.
[Ti] Título:Imiquimod treatment for lentigo maligna: LIMIT-1 trial.
[So] Source:Br J Dermatol;177(1):324-325, 2017 07.
[Is] ISSN:1365-2133
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Aminoquinolinas
Sarda Melanótica de Hutchinson
[Mh] Termos MeSH secundário: Antineoplásicos
Seres Humanos
Lentigo
Neoplasias Cutâneas
[Pt] Tipo de publicação:LETTER; COMMENT
[Nm] Nome de substância:
0 (Aminoquinolines); 0 (Antineoplastic Agents); P1QW714R7M (imiquimod)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171107
[Lr] Data última revisão:
171107
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170404
[St] Status:MEDLINE
[do] DOI:10.1111/bjd.15511


  5 / 1063 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28328709
[Au] Autor:Kaminaka C; Furukawa F; Yamamoto Y
[Ad] Endereço:Departments of *Dermatology, and †Cosmetic Dermatology and Photomedicine, Wakayama Medical University, Wakayama, Japan.
[Ti] Título:The Clinical and Histological Effect of a Low-Fluence Q-Switched 1,064-nm Neodymium: Yttrium-Aluminum-Garnet Laser for the Treatment of Melasma and Solar Lentigenes in Asians: Prospective, Randomized, and Split-Face Comparative Study.
[So] Source:Dermatol Surg;43(9):1120-1133, 2017 Sep.
[Is] ISSN:1524-4725
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The low-fluence Q-switched 1,064-nm neodymium:yttrium-aluminum-garnet laser (QSNYL) is popular for melasma treatment among Asians. OBJECTIVE: This study was to evaluate the clinical and histological effects of the low-fluence QSNYL for treatment of melasma and solar lentigenes. MATERIALS AND METHODS: In this randomized split-face clinical study, 22 patients with melasma or solar lentigo received low-fluence QSNYL weekly for 10 sessions on one cheek. The treatment efficacy was determined by Mexameter skin colorimetry, physician and patient assessment, and by evaluating histological changes. RESULTS: The treated sides had statistically significant reductions in the melanin and erythema indices (EI); 50.0% of melasma and 62.5% of solar lentigo patients had >50% clearance after the final treatment. The increased EI, vascularity, and mast cell activity in patients with melasma and large-sized solar lentigo showed no improvement. The recurrence rates were 16.7% and 12.7% for melasma and solar lentigo, respectively. Postinflammatory hyperpigmentation developed in 1 patient, but no serious side effects were noted. CONCLUSION: Low-fluence QSNYL is effective in treating melasma and small type solar lentigo in Asians. The authors' study also demonstrated that lesion thickness, vascularity, and mast cell activity can be used to predict the efficacy of the treatment of these lesions.
[Mh] Termos MeSH primário: Grupo com Ancestrais do Continente Asiático
Lasers de Estado Sólido/uso terapêutico
Lentigo/etnologia
Lentigo/radioterapia
Terapia com Luz de Baixa Intensidade
Melanose/etnologia
Melanose/radioterapia
[Mh] Termos MeSH secundário: Adulto
Bochecha/efeitos da radiação
Feminino
Seres Humanos
Lasers de Estado Sólido/efeitos adversos
Lentigo/patologia
Terapia com Luz de Baixa Intensidade/efeitos adversos
Melanose/patologia
Meia-Idade
Estudos Prospectivos
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Em] Mês de entrada:1708
[Cu] Atualização por classe:171010
[Lr] Data última revisão:
171010
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170323
[St] Status:MEDLINE
[do] DOI:10.1097/DSS.0000000000001120


  6 / 1063 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28074523
[Au] Autor:Gupta D; Chandrashekar L; Larizza L; Colombo EA; Fontana L; Gervasini C; Thappa DM; Rajappa M; Rajendiran KS; Sreenath GS; Kate V
[Ad] Endereço:Department of Dermatology and STD, Jawaharlal Institute of Postgraduate Medical Education & Research (JIPMER), Puducherry, India.
[Ti] Título:Familial gastrointestinal stromal tumors, lentigines, and café-au-lait macules associated with germline c-kit mutation treated with imatinib.
[So] Source:Int J Dermatol;56(2):195-201, 2017 Feb.
[Is] ISSN:1365-4632
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Familial lentiginosis syndromes are characterized by a wide array of manifestations resulting from activation of molecular pathways which control growth, proliferation, and differentiation of a broad range of tissues. Familial gastrointestinal stromal tumors (GISTs) are often accompanied by additional features like hyperpigmentation, mastocytosis, and dysphagia. They have been described with mutations in c-kit (most commonly), platelet-derived growth factor receptor A, neurofibromatosis-1, and succinate dehydrogenase genes. MATERIALS AND METHODS: We report on molecular characterization and tumor histopathology of two siblings in whom lentigines and café-au-lait macules were present along with multifocal GIST. Immuhistochemical analysis of CD34 and CD117 was performed on GIST biopsy samples from both siblings, while c-kit mutational analysis was done by PCR and direct sequencing on DNA from peripheral blood leukocytes of all family members and from paraffin-embedded gastric biopsy specimens of affected siblings. RESULTS: Histopathology revealed positive expression of CD117 and CD34. Mutational analysis showed the germline c.1676T>C mutation in c-kit exon 11, (p.(Val559Ala)), in the peripheral blood of both siblings and a second exon 11 mutation, c.1669T>A (p.(Trp557Arg)) in the tumor biopsy of one of them. Initiation of imatinib treatment resulted in striking resolution of their hyperpigmentation and a stable gastrointestinal disease in one of them. CONCLUSIONS: A c-kit mutational test in familial GISTs is indicated before initiation of imatinib therapy, as it can help predict tumor response to treatment.
[Mh] Termos MeSH primário: Manchas Café com Leite/genética
Neoplasias Gastrointestinais/genética
Tumores do Estroma Gastrointestinal/genética
Lentigo/genética
Proteínas Proto-Oncogênicas c-kit/genética
[Mh] Termos MeSH secundário: Adulto
Antineoplásicos/uso terapêutico
Manchas Café com Leite/complicações
Manchas Café com Leite/tratamento farmacológico
Feminino
Neoplasias Gastrointestinais/complicações
Neoplasias Gastrointestinais/tratamento farmacológico
Tumores do Estroma Gastrointestinal/complicações
Tumores do Estroma Gastrointestinal/tratamento farmacológico
Mutação em Linhagem Germinativa
Seres Humanos
Mesilato de Imatinib/uso terapêutico
Lentigo/complicações
Lentigo/tratamento farmacológico
Masculino
Linhagem
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antineoplastic Agents); 8A1O1M485B (Imatinib Mesylate); EC 2.7.10.1 (Proto-Oncogene Proteins c-kit)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170804
[Lr] Data última revisão:
170804
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170112
[St] Status:MEDLINE
[do] DOI:10.1111/ijd.13516


  7 / 1063 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27662050
[Au] Autor:Guss L; Goldman MP; Wu DC
[Ad] Endereço:Department of Dermatology, Johns Hopkins School of Medicine, Baltimore, Maryland Goldman, Butterwick, Groff, Fabi, and Wu, Cosmetic Laser Dermatology, San Diego, California.
[Ti] Título:Picosecond 532 nm Neodymium-Doped Yttrium Aluminium Garnet Laser for the Treatment of Solar Lentigines in Darker Skin Types: Safety and Efficacy.
[So] Source:Dermatol Surg;43(3):456-459, 2017 Mar.
[Is] ISSN:1524-4725
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Lasers de Estado Sólido/uso terapêutico
Lentigo/cirurgia
[Mh] Termos MeSH secundário: Adulto
Feminino
Seres Humanos
Lasers de Estado Sólido/efeitos adversos
Masculino
Meia-Idade
Estudos Retrospectivos
Fatores de Tempo
Resultado do Tratamento
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170907
[Lr] Data última revisão:
170907
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160924
[St] Status:MEDLINE
[do] DOI:10.1097/DSS.0000000000000922


  8 / 1063 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27593207
[Au] Autor:Peng F; Xue CH; Hwang SK; Li WH; Chen Z; Zhang JZ
[Ad] Endereço:Department of Dermatology, Peking University People's Hospital, Beijing, China.
[Ti] Título:Exposure to fine particulate matter associated with senile lentigo in Chinese women: a cross-sectional study.
[So] Source:J Eur Acad Dermatol Venereol;31(2):355-360, 2017 Feb.
[Is] ISSN:1468-3083
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Skin ageing especially senile lentigo directly affects self-esteem. For decades, senile lentigo has been associated with chronic exposure to solar radiation. However, a study conducted recently in Caucasian subjects suggested that exposure to air pollution was significantly correlated with extrinsic skin ageing, in particular senile lentigines. OBJECTIVE: To investigate the association between fine particulate matter (PM ) and skin ageing, particularly senile lentigo and seborrheic keratosis. METHODS: The study enrolled 400 Chinese women aged 40-90 years including 210 from the Yanqing county in Beijing (low PM exposure group) and 190 from the Xuanwumen in Beijing (high PM exposure group). Skin ageing symptoms, particularly senile lentigines and seborrheic keratoses, were clinically assessed using scores of intrinsic and extrinsic skin ageing. An ordinal logistic regression model was used to analyse the effect of PM on skin ageing adjusted for factors underlying skin ageing. RESULTS: In the study population of Xuanwumen, we found that senile lentigo on cheeks and back of hands was 1.48 times and 2.8 times higher, respectively, compared with those from Yanqing county. However, no association was found between PM and seborrheic keratosis. We found that other variables such as smoking, second-hand smoking, contact with fossil fuels and skin types were significantly associated with skin ageing. CONCLUSION: These results indicate that PM was another extrinsic factor promoting skin ageing.
[Mh] Termos MeSH primário: Lentigo/induzido quimicamente
Material Particulado
[Mh] Termos MeSH secundário: Adulto
Idoso
Idoso de 80 Anos ou mais
Estudos Transversais
Feminino
Seres Humanos
Lentigo/epidemiologia
Meia-Idade
Envelhecimento da Pele
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Particulate Matter)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170515
[Lr] Data última revisão:
170515
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160906
[St] Status:MEDLINE
[do] DOI:10.1111/jdv.13834


  9 / 1063 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27439996
[Au] Autor:Yasar S; Ersanli A; Göktay F; Aytekin S; Cebeci D; Günes P
[Ad] Endereço:Department of Dermatology, Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey.
[Ti] Título:Partial unilateral lentiginosis is mosaic neurofibromatosis type 1 or not?
[So] Source:J Dermatol;44(1):29-35, 2017 Jan.
[Is] ISSN:1346-8138
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Partial unilateral lentiginosis (PUL) is a rare pigmentation disorder characterized by numerous lentigines with sharp margins in the midline in one or more dermatomes. Its segmental pattern suggests that this presentation accompanied by café-au-lait spots, Lisch nodule or neurofibromas has a close relationship with mosaic neurofibromatosis type 1 or segmental neurofibromatosis (NF) in particular. In a group of 16 patients with PUL, who presented at the dermatology outpatient clinic between 1998 and 2015, an examination was made of consanguineous marriage in the family history, the presence of a similar lesion or NF in first-degree relatives, neurofibroma in the physical examination, the involvement pattern, axillary/inguinal freckling and the presence and number of café-au-lait spots. The ophthalmological examination investigated Lisch nodule and optic glioma. The skeletal system was examined for NF involvement. Of 16 patients, 13 (81.2%) were female and three (18.8%) were male with a mean age of 31.19 years (range, 15-48). There was no family history of PUL in any case. Consanguineous marriage was absent in 15 patients (93.8%). While there were accompanying café-au-lait spots in three patients (18.8%). Lisch nodule was an accompanying finding in three patients (18.8%). Axillary freckling was detected in four (25%) patients. Neurofibroma was found in only one patient. Although café-au-lait spots, axillary freckling, neurofibroma and Lisch nodule were present in a small number of the patients, the presence of the findings may be considered to be specific to NF suggests that PUL is a variant of mosaic NF-1. Genetic studies will help to further elucidate this subject.
[Mh] Termos MeSH primário: Manchas Café com Leite/diagnóstico
Hamartoma/diagnóstico
Doenças da Íris/diagnóstico
Lentigo/diagnóstico
Neurofibromatoses/diagnóstico
Neurofibromatose 1/diagnóstico
[Mh] Termos MeSH secundário: Adolescente
Adulto
Axila
Manchas Café com Leite/complicações
Feminino
Hamartoma/complicações
Seres Humanos
Doenças da Íris/complicações
Lentigo/complicações
Masculino
Meia-Idade
Neurofibromatoses/complicações
Neurofibromatose 1/complicações
Estudos Retrospectivos
Pele/patologia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170717
[Lr] Data última revisão:
170717
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160722
[St] Status:MEDLINE
[do] DOI:10.1111/1346-8138.13510


  10 / 1063 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:26757104
[Au] Autor:Hirobe S; Otsuka R; Iioka H; Quan YS; Kamiyama F; Asada H; Okada N; Nakagawa S
[Ad] Endereço:Laboratory of Biotechnology and Therapeutics, Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan.
[Ti] Título:Clinical study of a retinoic acid-loaded microneedle patch for seborrheic keratosis or senile lentigo.
[So] Source:Life Sci;168:24-27, 2017 Jan 01.
[Is] ISSN:1879-0631
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:AIMS: Pigmented lesions such as of seborrheic keratosis and senile lentigo, which are commonly seen on skin of people>50years of age, are considered unattractive and disfiguring because of their negative psychological impact. Drug therapy using all-trans retinoic acid (ATRA) is an attractive option for self-treatment at home. We have developed an ATRA-loaded microneedle patch (ATRA-MN) and confirmed the pharmacological effects of ATRA-MN application in mice. Here, we describe a clinical study to evaluate the safety and efficacy of ATRA-MN in subjects with seborrheic keratosis or senile lentigo. MAIN METHODS: ATRA-MN was applied to the lesion site of each subject for 6h once per week for 4weeks. The skin irritation reaction was scored to assess adverse reactions and blood tests were performed to evaluate the presence of systemic adverse reactions. To assess the treatment effect using ATRA-MN, the desquamation and whitening ability of the investigational skin was observed. KEY FINDINGS: Desquamation of the stratum corneum was observed following four ATRA-MN applications at 1-week intervals, but ATRA-MN applications did not induce severe local or systemic adverse effects. SIGNIFICANCE: These results showed that ATRA-MN treatment is promising as a safe and effective therapy for seborrheic keratosis and senile lentigo.
[Mh] Termos MeSH primário: Ceratolíticos/uso terapêutico
Ceratose Seborreica/tratamento farmacológico
Lentigo/tratamento farmacológico
Pele/efeitos dos fármacos
Adesivo Transdérmico
Tretinoína/uso terapêutico
[Mh] Termos MeSH secundário: Idoso
Idoso de 80 Anos ou mais
Feminino
Seres Humanos
Ceratolíticos/administração & dosagem
Ceratolíticos/efeitos adversos
Ceratose Seborreica/patologia
Lentigo/patologia
Masculino
Meia-Idade
Agulhas
Pele/metabolismo
Pele/patologia
Adesivo Transdérmico/efeitos adversos
Tretinoína/administração & dosagem
Tretinoína/efeitos adversos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Keratolytic Agents); 5688UTC01R (Tretinoin)
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170201
[Lr] Data última revisão:
170201
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160113
[St] Status:MEDLINE



página 1 de 107 ir para página                         
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde