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[PMID]:27328664
[Au] Autor:Arjona-Aguilera C; Rodríguez CC; Jiménez-Gallo D
[Ad] Endereço:Unidad de Gestión Clínica Dermatología y Venereología, Hospital Universitario Puerta del Mar, Cádiz, Spain.
[Ti] Título:sQuiz your knowledge: Generalized lesions resembling water droplets after treatment with idarubicin and all-trans retinoic acid.
[So] Source:Eur J Dermatol;26(3):329-31, 2016 Jun 01.
[Is] ISSN:1952-4013
[Cp] País de publicação:France
[La] Idioma:eng
[Mh] Termos MeSH primário: Protocolos de Quimioterapia Combinada Antineoplásica/efeitos adversos
Erupção por Droga/etiologia
Miliária/induzido quimicamente
[Mh] Termos MeSH secundário: Idoso
Feminino
Seres Humanos
Idarubicina/administração & dosagem
Idarubicina/efeitos adversos
Leucemia Promielocítica Aguda/tratamento farmacológico
Tretinoína/administração & dosagem
Tretinoína/efeitos adversos
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
5688UTC01R (Tretinoin); ZRP63D75JW (Idarubicin)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170623
[Lr] Data última revisão:
170623
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160623
[St] Status:MEDLINE
[do] DOI:10.1684/ejd.2016.2816


  2 / 178 MEDLINE  
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[PMID]:27192509
[Au] Autor:Reginatto FP; Villa DD; Cestari TF
[Ad] Endereço:Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
[Ti] Título:Benign skin disease with pustules in the newborn.
[So] Source:An Bras Dermatol;91(2):124-34, 2016 Apr.
[Is] ISSN:1806-4841
[Cp] País de publicação:Brazil
[La] Idioma:eng
[Ab] Resumo:The neonatal period comprises the first four weeks of life. It is a period of adaptation where the skin often presents several changes: transient lesions, resulting from a physiological response, others as a consequence of transient diseases and some as markers of severe disorders. The presence of pustules in the skin of the newborn is always a reason for the family and for the assisting doctor to be worried, since the newborn is especially vulnerable to bacterial, viral or fungal infection. However, the majority of neonatal skin pustules is not infectious, comprising the benign neonatal pustulosis. Benign neonatal pustuloses are a group of clinical disease characterized by pustular eruptions in which a contagious agent is not responsible for its etiology. The most common ones are erythema toxicum neonatorum, the transient neonatal pustular melanosis and the benign cephalic pustulosis. These dermatoses are usually benign, asymptomatic and self-limited. It is important that the dermatologist and the neonatologist can identify benign and transient lesions, those caused by genodermatoses, and especially differentiate between neonates with systemic involvement from those with benign skin lesions, avoiding unnecessary diagnostic tests and worries.
[Mh] Termos MeSH primário: Eritema/patologia
Dermatopatias Vesiculobolhosas/patologia
Pele/patologia
[Mh] Termos MeSH secundário: Diagnóstico Diferencial
Feminino
Seres Humanos
Recém-Nascido
Masculino
Melanose/patologia
Miliária/patologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170322
[Lr] Data última revisão:
170322
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160519
[St] Status:MEDLINE


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[PMID]:26381115
[Au] Autor:Terui H; Hashimoto A; Yamasaki K; Aiba S
[Ad] Endereço:Department of Dermatology, Tohoku University Graduate School of Medicine, Miyagi, Japan.
[Ti] Título:Milia En Plaque as a Distinct Follicular Hamartoma With Cystic Trichoepitheliomatous Features.
[So] Source:Am J Dermatopathol;38(3):212-7, 2016 Mar.
[Is] ISSN:1533-0311
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Milia en plaque (MEP) is an uncommon disorder characterized by an erythematous plaque containing numerous milia. The pathogenesis of MEP is not clear. The authors report a man with an erythematous plaque on the right retroauricular area, containing numerous white-yellow cysts varying in size. Histological examination showed that multiple cystic structures at various levels of the dermis that were lined by stratified squamous epithelium and contained keratinous material-these findings were consistent with the diagnosis of multiple milia. In addition to epidermal cysts, however, the lesion consisted of a branched proliferation of pale-staining keratinocytes lined with basal keratinocytes budding from the overlying epidermis. Moreover, some cysts were formed within the branched epithelial proliferation, had thicker cyst walls than the ordinary milium, or had irregular or branched projections toward the surrounding dermis. From these findings, the authors conclude that MEP is a distinct follicular hamartoma with cystic trichoepitheliomatous features.
[Mh] Termos MeSH primário: Cisto Epidérmico/patologia
Hamartoma/patologia
Miliária/patologia
Dermatopatias/patologia
[Mh] Termos MeSH secundário: Adulto
Seres Humanos
Masculino
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1611
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150919
[St] Status:MEDLINE
[do] DOI:10.1097/DAD.0000000000000445


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[PMID]:26611484
[Au] Autor:Yanamandra U; Khadwal A; Malhotra P; Varma S
[Ad] Endereço:Deaprtment of Internal Medicine, Armed Forces Medical College, Pune, Maharashtra, India Department of Hematology, Internal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
[Ti] Título:Miliaria crystallina: relevance in patients with hemato-oncological febrile neutropenia.
[So] Source:BMJ Case Rep;2015, 2015 Nov 26.
[Is] ISSN:1757-790X
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Neutropenia Febril/complicações
Miliária/complicações
[Mh] Termos MeSH secundário: Adolescente
Adulto
Antineoplásicos/uso terapêutico
Neutropenia Febril/diagnóstico
Seres Humanos
Masculino
Miliária/diagnóstico
Leucemia-Linfoma Linfoblástico de Células Precursoras/complicações
Leucemia-Linfoma Linfoblástico de Células Precursoras/tratamento farmacológico
Clima Tropical
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antineoplastic Agents)
[Em] Mês de entrada:1609
[Cu] Atualização por classe:171126
[Lr] Data última revisão:
171126
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151128
[St] Status:MEDLINE


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[PMID]:26437285
[Au] Autor:Kimes K; Beasley K; Dalton SR
[Ad] Endereço:San Antonio Military Medical Center, Fort Sam Houston.
[Ti] Título:Eruptive milia and comedones during treatment with dovitinib.
[So] Source:Dermatol Online J;21(9), 2015 Sep 17.
[Is] ISSN:1087-2108
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Dovitinib (TKI258) is a multi-targeted receptor tyrosine kinase inhibitor currently under clinical trials for a wide variety of cancers. Well-known side effects include nausea, vomiting, diarrhea, and fatigue. To date, there have only been only two reported cases with skin manifestations as a side effect. We report a case of eruptive facial milia and comedones in the setting of dovitinib treatment for metastatic gastrointestinal cancer. This case is unique as the clinical presentation was more rapid in onset and showed an absence of inflammatory lesions. Although the pathogenesis for skin manifestations is presently unknown, we present this case to increase awareness of potentially under-reported cutaneous side effects.
[Mh] Termos MeSH primário: Antineoplásicos/efeitos adversos
Benzimidazóis/efeitos adversos
Dermatoses Faciais/induzido quimicamente
Neoplasias Gastrointestinais/tratamento farmacológico
Miliária/induzido quimicamente
Quinolonas/efeitos adversos
[Mh] Termos MeSH secundário: Erupção por Droga/etiologia
Neoplasias Gastrointestinais/patologia
Seres Humanos
Ceratose
Masculino
Meia-Idade
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (4-amino-5-fluoro-3-(5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl)quinolin-2(1H)-one); 0 (Antineoplastic Agents); 0 (Benzimidazoles); 0 (Quinolones)
[Em] Mês de entrada:1607
[Cu] Atualização por classe:161125
[Lr] Data última revisão:
161125
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151006
[St] Status:MEDLINE


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[PMID]:26177262
[Au] Autor:Jeskowiak A; Luger TA; Böhm M
[Ad] Endereço:Department of Dermatology, General Dermatology and Venereology, Von-Esmarch-Straße 58, 48149, Münster.
[Ti] Título:Hypotrichosis, milia, brachydactyly, and frenula.
[So] Source:J Dtsch Dermatol Ges;13(9):934-6, 2015 Sep.
[Is] ISSN:1610-0387
[Cp] País de publicação:Germany
[La] Idioma:eng
[Mh] Termos MeSH primário: Braquidactilia/diagnóstico
Dermatoses Faciais/diagnóstico
Hipotricose/diagnóstico
Miliária/diagnóstico
Síndromes Orofaciodigitais/diagnóstico
Dermatoses do Couro Cabeludo/diagnóstico
[Mh] Termos MeSH secundário: Braquidactilia/genética
Braquidactilia/terapia
Pré-Escolar
Dermatoses Faciais/genética
Dermatoses Faciais/terapia
Feminino
Seres Humanos
Hipotricose/genética
Hipotricose/terapia
Ceratose
Miliária/genética
Miliária/terapia
Síndromes Orofaciodigitais/genética
Síndromes Orofaciodigitais/terapia
Dermatoses do Couro Cabeludo/genética
Dermatoses do Couro Cabeludo/terapia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1610
[Cu] Atualização por classe:170103
[Lr] Data última revisão:
170103
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150716
[St] Status:MEDLINE
[do] DOI:10.1111/ddg.12759


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[PMID]:26159354
[Au] Autor:Bandino JP; Hang A; Norton SA
[Ad] Endereço:Dermatology, USAF Hospital Langley, Hampton, VA, USA. tantomed@gmail.com.
[Ti] Título:The Infectious and Noninfectious Dermatological Consequences of Flooding: A Field Manual for the Responding Provider.
[So] Source:Am J Clin Dermatol;16(5):399-424, 2015 Oct.
[Is] ISSN:1179-1888
[Cp] País de publicação:New Zealand
[La] Idioma:eng
[Ab] Resumo:Meteorological data show that disastrous floods are increasingly frequent and more severe in recent years, perhaps due to climatic changes such as global warming. During and after a flood disaster, traumatic injuries, communicable diseases, chemical exposures, malnutrition, decreased access to care, and even mental health disorders dramatically increase, and many of these have dermatological manifestations. Numerous case reports document typical and atypical cutaneous infections, percutaneous trauma, immersion injuries, noninfectious contact exposures, exposure to wildlife, and exacerbation of underlying skin diseases after such disasters as the 2004 Asian tsunami, Hurricane Katrina in 2005, and the 2010 Pakistan floods. This review attempts to provide a basic field manual of sorts to providers who are engaged in care after a flooding event, with particular focus on the infectious consequences. Bacterial pathogens such as Staphylococcus and Streptococcus are still common causes of skin infections after floods, with atypical bacteria also greatly increased. Vibrio vulnificus is classically associated with exposure to saltwater or brackish water. It may present as necrotizing fasciitis with hemorrhagic bullae, and treatment consists of doxycycline or a quinolone, plus a third-generation cephalosporin and surgical debridement. Atypical mycobacterial infections typically produce indolent cutaneous infections, possibly showing sporotrichoid spread. A unique nontuberculous infection called spam has recently been identified in Satowan Pacific Islanders; combination antibiotic therapy is recommended. Aeromonas infection is typically associated with freshwater exposure and, like Vibrio infections, immunocompromised or cirrhotic patients are at highest risk for severe disease, such as necrotizing fasciitis and sepsis. Various antibiotics can be used to treat Aeromonas infections. Melioidosis is seen mainly in Southeast Asia and Australia, particularly in rice farmers, and can remain latent for many years before presenting as the host's immunocompetence wanes. It can present with a variety of skin findings or as a nonspecific febrile illness, and preferred treatment consists of ceftazidime or a carbapenem with trimethoprim/sulfamethoxazole (TMP/SMX) for 2 weeks, then continuing TMP/SMX for at least 3 months. Leptospirosis is a waterborne zoonosis that is often prevalent after heavy rains or flooding. Different forms exist, including Fort Bragg fever, which produces a distinctive erythematous papular rash on the shins. Doxycycline is often sufficient; however, volume and potassium repletion may be necessary if renal involvement exists. Chromobacterium violaceum infection may occur after open skin is exposed to stagnant or muddy water. Cultured colonies produce a unique violacein pigment, and treatment typically consists of a carbapenem. Both typical and atypical fungal infections are increased in the flooding disaster scenario, such as dermatophytosis, chromoblastomycosis, blastomycosis, and mucormycosis. Appropriate antifungals should be used. In addition, land inundated with water expands the habitat for parasites and/or vectors, thus increased vigilance for regional parasitic infections is necessary after a flood. Lastly, noninfectious consequences of a flooding disaster are also common and include miliaria, immersion foot syndromes, irritant and allergic contact dermatitis, traumatic wounds and animal bites, and arthropod assault, as well as exacerbation of existing skin conditions such as atopic dermatitis, psoriasis, and alopecia areata due to increased stress or nonavailability of daily medications.
[Mh] Termos MeSH primário: Dermatomicoses/diagnóstico
Dermatomicoses/terapia
Inundações
Dermatopatias Bacterianas/diagnóstico
Dermatopatias Bacterianas/terapia
Ferimentos e Lesões
[Mh] Termos MeSH secundário: Dermatite de Contato/etiologia
Dermatite de Contato/terapia
Dermatomicoses/microbiologia
Água Doce
Seres Humanos
Pé de Imersão/etiologia
Pé de Imersão/terapia
Miliária/etiologia
Miliária/terapia
Água do Mar
Dermatopatias Bacterianas/microbiologia
Dermatopatias Parasitárias/diagnóstico
Dermatopatias Parasitárias/parasitologia
Ferimentos e Lesões/etiologia
Ferimentos e Lesões/terapia
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1606
[Cu] Atualização por classe:160707
[Lr] Data última revisão:
160707
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150711
[St] Status:MEDLINE
[do] DOI:10.1007/s40257-015-0138-4


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[PMID]:25775647
[Au] Autor:Kirchhof MG; Collins D; Crawford RI; Au S
[Ad] Endereço:Department of Dermatology and Skin Science and Division of Rheumatology, Department of Medicine, University of British Columbia, and Division of Dermatology, Department of Medicine, St. Paul's Hospital, Providence Health Care, Vancouver, BC kirchhof.mark@gmail.com.
[Ti] Título:Multiple Cutaneous Creamy Papules and Nodules: A Case of Miliarial Gout.
[So] Source:J Cutan Med Surg;19(3):317-9, 2015 May-Jun.
[Is] ISSN:1203-4754
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Tophaceous gout is the nonarticular deposition of monosodium urate resulting from a disorder in purine metabolism that causes an elevation of serum uric acid. Cutaneous variants of tophaceous gout include papular, nodular, ulcerative, and pustular forms. OBJECTIVE: We present a case of a 67-year-old man who presented with multiple cutaneous creamy white papules and nodules. A biopsy was taken, and a diagnosis of cutaneous tophaceous gout was made. The treatment and pathophysiology are discussed. CONCLUSION: Miliarial gout is a rare form of cutaneous tophaceous gout that is treated using xanthine oxidase inhibitors such as allopurinol and febuxostat or uricosurics such as probenecid.
[Mh] Termos MeSH primário: Gota/diagnóstico
Miliária/diagnóstico
[Mh] Termos MeSH secundário: Idoso
Gota/patologia
Seres Humanos
Masculino
Miliária/patologia
Coxa da Perna/patologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1510
[Cu] Atualização por classe:150610
[Lr] Data última revisão:
150610
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150317
[St] Status:MEDLINE
[do] DOI:10.2310/7750.2014.14106


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[PMID]:25401490
[Au] Autor:Wendemagegn E; Tirumalae R; Böer-Auer A
[Ad] Endereço:Federal Ministry of Health Ethiopia, Addis Abeba, Ethiopia.
[Ti] Título:Histopathological and immunohistochemical features of nodular podoconiosis.
[So] Source:J Cutan Pathol;42(3):173-81, 2015 Mar.
[Is] ISSN:1600-0560
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Podoconiosis is a familial geochemical dermatosis which is common in Ethiopia but relatively unknown in Europe/United States. It is related to exposure of bare feet to volcanic soil and presents with extensive bilateral lymphedema of legs and feet. Histopathological and immunohistochemical features of it have not been described yet. OBJECTIVES: The objectives of this study are to characterize podoconiosis histopathologically and immunohistochemically and to increase awareness of the disease. METHODS: Ten specimens of fully developed podoconiosis were examined with hematoxylin/eosin, periodic acid-Schiff, Gram, elastica-van Gieson stainings, with immunohistochemistry (CD3,CD20,CD31,CD68,CD138, tryptase, podoplanin, collagen IV), and with polymerase chain reaction (PCR) for human papillomavirus (HPV)-specific DNA. RESULTS: All specimens showed verrucous acanthosis and papillomatosis. Eccrine ducts demonstrated hyperplasia, syringofibroadenomatous changes and miliaria. Dermal collagen bundles were thickened, and elastic fibers were dramatically reduced. A moderate lymphoplasmacytic infiltrate was joined by mast cells and scattered macrophages; neutrophils and eosinophils were sparse. Blood vessels were increased, dilated, and often sclerotic while lymphatics were reduced and largely not dilated. HPV-PCR was negative in all specimens. CONCLUSIONS: Podoconiosis demonstrates distinctive changes of chronic lymphedema with extensive sclerosis, loss of elastic fibers, verrucous acanthosis (not HPV induced) and reactive changes of eccrine structures. Mast cells, macrophages and altered blood vessels may be involved in the pathogenesis.
[Mh] Termos MeSH primário: Elefantíase/metabolismo
Elefantíase/patologia
[Mh] Termos MeSH secundário: Adulto
Idoso
Elefantíase/virologia
Etiópia/epidemiologia
Feminino
Seres Humanos
Hiperplasia/patologia
Imuno-Histoquímica
Perna (Membro)/patologia
Masculino
Meia-Idade
Miliária/patologia
Papiloma/patologia
Papillomaviridae/genética
Papillomaviridae/isolamento & purificação
Reação em Cadeia da Polimerase/métodos
Doenças Raras/epidemiologia
Doenças Raras/metabolismo
Doenças Raras/patologia
Doenças Raras/virologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1603
[Cu] Atualização por classe:150324
[Lr] Data última revisão:
150324
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:141118
[St] Status:MEDLINE
[do] DOI:10.1111/cup.12441


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[PMID]:25390622
[Au] Autor:Tey HL; Tay EY; Cao T
[Ad] Endereço:National Skin Centre, Singapore.
[Ti] Título:In vivo imaging of miliaria profunda using high-definition optical coherence tomography: diagnosis, pathogenesis, and treatment.
[So] Source:JAMA Dermatol;151(3):346-8, 2015 Mar.
[Is] ISSN:2168-6084
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Hipo-Hidrose/etiologia
Miliária/diagnóstico
Tomografia de Coerência Óptica/métodos
[Mh] Termos MeSH secundário: Adulto
Seres Humanos
Masculino
Miliária/patologia
Miliária/terapia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1505
[Cu] Atualização por classe:160524
[Lr] Data última revisão:
160524
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:141113
[St] Status:MEDLINE
[do] DOI:10.1001/jamadermatol.2014.3612



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