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[PMID]:28467207
[Au] Autor:Moon S
[Ad] Endereço:a Department of Nursing , College of Medicine, University of Ulsan , Ulsan , South Korea.
[Ti] Título:Unhealthy Lifestyle Behaviors in Korean People with Metabolic Syndrome.
[So] Source:J Community Health Nurs;34(2):69-79, 2017 Apr-Jun.
[Is] ISSN:1532-7655
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:This study identified factors associated with unhealthy lifestyle behaviors in people with metabolic syndrome in South Korea. The sample consisted of 1,207 subjects with metabolic syndrome from the Sixth Korea National Health and Nutrition Examination Survey conducted in 2014. High-risk alcohol consumption, smoking, aerobic physical activity, leisure physical activity, excessive carbohydrate intake, and fat intake were measured. A secondary data analysis was performed using chi-square tests and logistic regression. Gender was associated with all unhealthy behaviors. The number of metabolic syndrome components, a poor perceived health status, and attempts to control weight were associated with physical inactivity. Those findings may be helpful to develop a tailored lifestyle modification programs for people with metabolic syndrome.
[Mh] Termos MeSH primário: Comportamentos Relacionados com a Saúde
Síndrome Metabólica/psicologia
[Mh] Termos MeSH secundário: Adulto
Idoso
Consumo de Bebidas Alcoólicas/efeitos adversos
Consumo de Bebidas Alcoólicas/epidemiologia
Distribuição de Qui-Quadrado
Estudos Transversais
Carboidratos da Dieta/administração & dosagem
Carboidratos da Dieta/efeitos adversos
Gorduras na Dieta/administração & dosagem
Gorduras na Dieta/efeitos adversos
Exercício
Feminino
Seres Humanos
Estilo de Vida
Modelos Logísticos
Masculino
Meia-Idade
Inquéritos Nutricionais
República da Coreia/epidemiologia
Fatores Sexuais
Fumar/efeitos adversos
Fumar/epidemiologia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Dietary Carbohydrates); 0 (Dietary Fats)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:IM; N
[Da] Data de entrada para processamento:170504
[St] Status:MEDLINE
[do] DOI:10.1080/07370016.2017.1304145


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[PMID]:29203751
[Au] Autor:Placzkowska S; Pawlik-Sobecka L; Kokot I; Piwowar A
[Ad] Endereço:Diagnostyczne Laboratorium Naukowo-Dydaktyczne, Wydzial Farmaceutyczny Z Oddzialem Analityki Medycznej, Uniwersytet Medyczny We Wroclawiu, Wroclaw, Polska.
[Ti] Título:[Metabolic syndrome - a new look at a known problem].
[So] Source:Wiad Lek;70(5):970-976, 2017.
[Is] ISSN:0043-5147
[Cp] País de publicação:Poland
[La] Idioma:pol
[Ab] Resumo:Civilization changes over the past decades have been associated with an increase in the incidence of various metabolic disorders, especially in the carbohydrate-lipid metabolism, which are not always associated with obesity. Metabolic syndrome, despite changing criteria of recognition, is a clinically established risk factor for civilization diseases development. On the other side, the incidence of complex metabolic disorders in non-obese people is increasing, which is referred to in the literature as metabolic obesity with normal body mass. Both, excess visceral fatty tissue and insulin resistance are common components in the diagnosis of these syndromes and their occurrence is associated with an increased risk of developing type 2 diabetes and cardiovascular disease. Some researchers also point out the possibility of occurrence of so-called metabolically healthy obesity. Identify people with such a constellation of disorders is still difficult in clinical practice because of different and changing diagnostic criteria. Data from the literature about epidemiology of these disorders are inconclusive and do not allow for a reliable assessment of such disorders prevalence in population. The increasing rate of the metabolic syndrome and metabolic obesity with normal body weight occurrence in the general population pays attention to the importance of this problem, especially in primary health care. Preventive programs are primarily aimed at older people with high risk of cardiovascular diseases development and focused on detecting metabolic syndrome traits. Nevertheless, very often, young, potentially healthy individuals, are not subject to screening programs, even though incidence of metabolic obesity with normal body weight in this population is very high nowadays.
[Mh] Termos MeSH primário: Peso Corporal
Síndrome Metabólica/metabolismo
Obesidade/metabolismo
[Mh] Termos MeSH secundário: Índice de Massa Corporal
Doenças Cardiovasculares/prevenção & controle
Seres Humanos
Lipoproteínas HDL/metabolismo
Lipoproteínas LDL/metabolismo
Síndrome Metabólica/complicações
Obesidade/complicações
Fatores de Risco
Triglicerídeos/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Lipoproteins, HDL); 0 (Lipoproteins, LDL); 0 (Triglycerides)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171206
[St] Status:MEDLINE


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[PMID]:27778642
[Au] Autor:Garibay-Nieto N; Queipo-García G; Alvarez F; Bustos M; Villanueva E; Ramírez F; León M; Laresgoiti-Servitje E; Duggirala R; Macías T; Cuevas S; Jalife A; Fonseca-Sánchez M; Serratos F; López-Alvarenga JC
[Ad] Endereço:Children and Adolescent Obesity Clinic.
[Ti] Título:Effects of Conjugated Linoleic Acid and Metformin on Insulin Sensitivity in Obese Children: Randomized Clinical Trial.
[So] Source:J Clin Endocrinol Metab;102(1):132-140, 2017 Jan 01.
[Is] ISSN:1945-7197
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Context: Insulin resistance precedes metabolic syndrome abnormalities and may promote cardiovascular disease and type 2 diabetes in children with obesity. Results of lifestyle modification programs have been discouraging, and the use of adjuvant strategies has been necessary. Objective: This study aimed to evaluate the effects of metformin and conjugated linoleic acid (CLA) on insulin sensitivity, measured via euglycemic-hyperinsulinemic clamp technique and insulin pathway expression molecules in muscle biopsies of children with obesity. Design: A randomized, double-blinded, placebo-controlled clinical trial was conducted. Setting: Children with obesity were randomly assigned to receive metformin, CLA, or placebo. Results: Intervention had a positive effect in all groups. For insulin sensitivity Rd value (mg/kg/min), there was a statistically significant difference between the CLA vs placebo (6.53 ± 2.54 vs 5.05 ± 1.46, P = 0.035). Insulinemia and homeostatic model assessment of insulin resistance significantly improved in the CLA group (P = 0.045). After analysis of covariance was performed and the influence of body mass index, age, Tanner stage, prescribed diet, and fitness achievement was controlled, a clinically relevant effect size on insulin sensitivity remained evident in the CLA group (37%) and exceeded lifestyle program benefits. Moreover, upregulated expression of the insulin receptor substrate 2 was evident in muscle biopsies of the CLA group. Conclusions: Improvement of insulin sensitivity, measured via euglycemic-hyperinsulinemic clamp and IRS2 upregulation, favored patients treated with CLA.
[Mh] Termos MeSH primário: Doenças Cardiovasculares/prevenção & controle
Hipoglicemiantes/uso terapêutico
Resistência à Insulina
Ácidos Linoleicos Conjugados/uso terapêutico
Síndrome Metabólica/prevenção & controle
Metformina/uso terapêutico
Obesidade/tratamento farmacológico
[Mh] Termos MeSH secundário: Adolescente
Biomarcadores/análise
Glicemia/análise
Composição Corporal
Criança
Método Duplo-Cego
Quimioterapia Combinada
Feminino
Seguimentos
Seres Humanos
Insulina/sangue
Lipídeos/análise
Masculino
Obesidade/complicações
Prognóstico
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (Biomarkers); 0 (Blood Glucose); 0 (Hypoglycemic Agents); 0 (Insulin); 0 (Linoleic Acids, Conjugated); 0 (Lipids); 9100L32L2N (Metformin)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:161026
[St] Status:MEDLINE
[do] DOI:10.1210/jc.2016-2701


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[PMID]:29427589
[Au] Autor:Vieira AJ; Beserra FP; Souza MC; Totti BM; Rozza AL
[Ad] Endereço:São Paulo State University (UNESP), Institute of Biosciences, Department of Morphology, Botucatu, Brazil.
[Ti] Título:Limonene: Aroma of innovation in health and disease.
[So] Source:Chem Biol Interact;283:97-106, 2018 Mar 01.
[Is] ISSN:1872-7786
[Cp] País de publicação:Ireland
[La] Idioma:eng
[Ab] Resumo:Natural products obtained in dietary components may aid the prevention and treatment of a variety of diseases. Reports in the scientific literature have demonstrated that the consumption of terpenes is a successful alternative in the treatment of several diseases, triggering beneficial biological effects in clinical and preclinical studies. The monoterpene limonene is largely used in alimentary items, cleaning products, and it is one of the most frequent fragrances used in cosmetics formulation. The therapeutic effects of limonene have been extensively studied, proving anti-inflammatory, antioxidant, antinociceptive, anticancer, antidiabetic, antihyperalgesic, antiviral, and gastroprotective effects, among other beneficial effects in health. In this review, we collected, presented, and analyzed evidence from the scientific literature regarding the usage of limonene and its activities and underlying mechanisms involved in combating diseases. The highlighting of limonene applications could develop a useful targeting of innovative research in this field as well as the development of a limonene-based phytomedicine which could be used in a variety of conditions of health and disease.
[Mh] Termos MeSH primário: Cicloexenos/uso terapêutico
Síndrome Metabólica/prevenção & controle
Terpenos/uso terapêutico
[Mh] Termos MeSH secundário: Analgésicos/química
Analgésicos/farmacologia
Animais
Anti-Inflamatórios/química
Anti-Inflamatórios/farmacologia
Anti-Inflamatórios/uso terapêutico
Antineoplásicos Fitogênicos/química
Antineoplásicos Fitogênicos/farmacologia
Antineoplásicos Fitogênicos/uso terapêutico
Antioxidantes/química
Antioxidantes/farmacologia
Cicloexenos/química
Cicloexenos/farmacologia
Seres Humanos
Síndrome Metabólica/tratamento farmacológico
Síndrome Metabólica/patologia
Osteoartrite/tratamento farmacológico
Estresse Oxidativo/efeitos dos fármacos
Plantas/química
Plantas/metabolismo
Terpenos/química
Terpenos/farmacologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Analgesics); 0 (Anti-Inflammatory Agents); 0 (Antineoplastic Agents, Phytogenic); 0 (Antioxidants); 0 (Cyclohexenes); 0 (Terpenes); 9MC3I34447 (limonene)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180305
[Lr] Data última revisão:
180305
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180211
[St] Status:MEDLINE


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[PMID]:29351564
[Au] Autor:Naran NH; Haagensen M; Crowther NJ
[Ad] Endereço:Department of Chemical Pathology, National Health Laboratory Service, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
[Ti] Título:Steatosis in South African women: How much and why?
[So] Source:PLoS One;13(1):e0191388, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Globally, steatosis is the commonest type of liver pathology and is closely associated with obesity and the metabolic syndrome. Obesity is common in urban African females but no data is available on hepatic fat content in this population group when compared to other ethnic groups. The aim of this study was therefore to compare hepatic fat content in woman from different ethnic groups in South Africa and to characterise the principle determinants of liver fat. MATERIALS AND METHODS: A convenience sample of 106 (48 Indian, 29 African and 29 Caucasian) female volunteers aged 20-60 years and having no history of cardiometabolic disorders were recruited. Hepatic fat was determined from CT scans using the liver-spleen attenuation ratio (LAR), which decreases with increasing levels of hepatic fat. Anthropometric and cardiometabolic parameters were measured with insulin resistance determined using the HOMA index and dysglycaemia defined as fasting glucose ≥5.60 mmol/L. RESULTS: The African subjects had significantly lower hepatic fat content (LAR as median [interquartile range]: 1.35 [1.28, 1.41]) than the Indian (1.22 [1.10, 1.35]; p<0.005) and Caucasian (1.27 [1.16, 1.33]; p<0.05) females even though they had significantly higher BMIs than both groups (p<0.0005 and p<0.05, respectively). Linear regression showed that: subcutaneous abdominal fat was a significant (unstandardised ß = 0.007; p = 0.03) negative, whilst insulin resistance (ß = -0.97; p = 0.01) and dysglycaemia (ß = -3.58; p = 0.01) were significant positive determinants of liver fat; higher hepatic fat levels in subjects with the metabolic syndrome were explained by insulin resistance and dysglycaemia. DISCUSSION: African ethnicity is associated with low liver fat content. Subcutaneous abdominal fat protects against steatosis, possibly by acting as a triglyceride reservoir. Insulin resistance and dysglycaemia lead to greater hepatic fat deposition and explain higher liver fat levels in subjects with the metabolic syndrome. These observations must be further investigated in longitudinal surveys.
[Mh] Termos MeSH primário: Fígado Gorduroso/patologia
[Mh] Termos MeSH secundário: Tecido Adiposo/diagnóstico por imagem
Tecido Adiposo/patologia
Adulto
Grupo com Ancestrais do Continente Africano
Antropometria
Índice de Massa Corporal
Estudos Transversais
Grupo com Ancestrais do Continente Europeu
Fígado Gorduroso/diagnóstico por imagem
Fígado Gorduroso/metabolismo
Feminino
Seres Humanos
Resistência à Insulina
Modelos Lineares
Fígado/diagnóstico por imagem
Fígado/patologia
Síndrome Metabólica/diagnóstico por imagem
Síndrome Metabólica/metabolismo
Síndrome Metabólica/patologia
Meia-Idade
África do Sul
Gordura Subcutânea Abdominal/diagnóstico por imagem
Gordura Subcutânea Abdominal/patologia
Tomografia Computadorizada por Raios X
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180305
[Lr] Data última revisão:
180305
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180120
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0191388


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[PMID]:29258743
[Au] Autor:Kawada T
[Ad] Endereço:Department of Hygiene and Public Health, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-Ku, Tokyo 113-8602, Japan. Electronic address: kawada@nms.ac.jp.
[Ti] Título:Association between metabolic syndrome and chronic kidney disease.
[So] Source:Clin Chim Acta;478:44, 2018 03.
[Is] ISSN:1873-3492
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Mh] Termos MeSH primário: Síndrome Metabólica
Insuficiência Renal Crônica
[Mh] Termos MeSH secundário: Doença Crônica
Seres Humanos
Nefropatias
Fatores de Risco
[Pt] Tipo de publicação:LETTER; COMMENT
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180305
[Lr] Data última revisão:
180305
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171221
[St] Status:MEDLINE


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[PMID]:29241745
[Au] Autor:Karadag AS; Lavery MJ
[Ad] Endereço:Department of Dermatology, Istanbul Medeniyet University, Istanbul, Turkey. Electronic address: karadagaserap@gmail.com.
[Ti] Título:Skin and the metabolic syndrome.
[So] Source:Clin Dermatol;36(1):1-2, 2018 Jan - Feb.
[Is] ISSN:1879-1131
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Síndrome Metabólica
Pele
[Mh] Termos MeSH secundário: Seres Humanos
[Pt] Tipo de publicação:EDITORIAL; COMMENT
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180305
[Lr] Data última revisão:
180305
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171216
[St] Status:MEDLINE


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[PMID]:29179831
[Au] Autor:Chee GL; Wynaden D; Heslop K
[Ad] Endereço:School of Nursing, Midwifery and Paramedicine, Curtin University, Perth, Western Australia, Australia. Electronic address: Johnathan.Chee@health.wa.gov.au.
[Ti] Título:Improving metabolic monitoring rate for young people aged 35 and younger taking antipsychotic medications to treat a psychosis: A literature review.
[So] Source:Arch Psychiatr Nurs;31(6):624-633, 2017 12.
[Is] ISSN:1532-8228
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Young people aged 35 and younger who are taking antipsychotic medications to treat a psychosis are a high risk for developing metabolic syndrome due to the adverse effects of the medications. This paper reports the finding of a review of literature to identify interventions to improve metabolic monitoring rates in this group. A review of 478 studies identified 15 articles which met the inclusion criteria. Five articles reported single-intervention studies and the remaining integrated two or more interventions to improve uptake level of metabolic monitoring. As metabolic syndrome can be detected early through metabolic monitoring in young people taking antipsychotics, early intervention is important to improve their physical health trajectory.
[Mh] Termos MeSH primário: Antipsicóticos/efeitos adversos
Síndrome Metabólica/etiologia
Transtornos Psicóticos/complicações
[Mh] Termos MeSH secundário: Antipsicóticos/uso terapêutico
Seres Humanos
Transtornos Psicóticos/tratamento farmacológico
Fatores de Risco
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Antipsychotic Agents)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180306
[Lr] Data última revisão:
180306
[Sb] Subgrupo de revista:IM; N
[Da] Data de entrada para processamento:171129
[St] Status:MEDLINE


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[PMID]:29390327
[Au] Autor:Yu CY; Chen FP; Chen LW; Kuo SF; Chien RN
[Ad] Endereço:Department of Gastroenterology and Hepatology.
[Ti] Título:Association between metabolic syndrome and bone fracture risk: A community-based study using a fracture risk assessment tool.
[So] Source:Medicine (Baltimore);96(50):e9180, 2017 Dec.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Osteoporosis and metabolic syndrome (MS) share similar risk factors. Previous studies of association between bone marrow density (BMD) and MS are controversial. Moreover, some studies revealed that MS is associated with BMD but not with bone fracture. In clinical practice, patients pay more attention to bone fracture risk than BMD values. Hence, this study aimed to evaluate the association between MS and the 10-year bone fracture risk probability using a fracture risk assessment tool (FRAX) from community-based data. From March 2014 to August 2015, 2689 participants (897 men and 1792 women) were enrolled in this study. Inflammatory cytokines, such as tumor necrosis factor alpha and C-reactive protein, and adipokines were included for analysis.The mean age was 60.2 ±â€Š10.7 years in men and 58.9 ±â€Š9.6 years in women. The percentage of MS was 27.6% in men and 27.9% in women. Participants were divided into 2 groups, those with or without MS. Compared with women without MS, women with MS had a higher rate of fracture risk (22.8% vs 16.3%, P = .001). In contrast, men with MS had a lower rate of fracture risk then men without MS (5.6% vs 12.3%, P = .004). However, MS loss the association with a high bone fracture risk in men based on multivariate logistical regression analysis, after adjusting for confounding factor of body mass index (BMI). Conclusively, the result of regression analysis between MS and the bone fracture risk may be different in men and women, and BMI was an important confounding factor to interfere with the regression analysis.
[Mh] Termos MeSH primário: Fraturas Ósseas/etiologia
Síndrome Metabólica/complicações
[Mh] Termos MeSH secundário: Biomarcadores/sangue
Densidade Óssea
Feminino
Seres Humanos
Masculino
Meia-Idade
Medição de Risco
Fatores de Risco
Taiwan
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Biomarkers)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180301
[Lr] Data última revisão:
180301
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180203
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000009180


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[PMID]:29390261
[Au] Autor:Rui W; Xiangyu D; Fang X; Long G; Yi Y; Wenjuan W; Tian H; Xiaoning Z; Yong Z; Jianfeng F; Hengjin L; Chengxin L
[Ad] Endereço:Department of Dermatology, Chinese PLA General Hospital, Medical College of Chinese PLA, Beijing, China.
[Ti] Título:Metabolic syndrome affects narrow-band UVB phototherapy response in patients with psoriasis.
[So] Source:Medicine (Baltimore);96(50):e8677, 2017 Dec.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Psoriasis is a chronic inflammatory skin disease. Metabolic syndrome (MS) is a combination of central obesity, dyslipidemia, glucose intolerance, and elevated blood pressure. Many epidemiological surveys have revealed the association of psoriasis with MS. Narrowband ultraviolet radiation b (NB-UVB) is an effective and widely used treatment for psoriasis. The purpose of this study was to investigate whether the presence of MS in patient with psoriasis affects NB-UVB treatment and whether this syndrome correlates with systemic inflammation.From June 2016 to December 2016, 243 adults with a diagnosis of psoriasis vulgaris eligible to treatment with NB-UVB were admitted to the phototherapy unit of Dermatology department, Chinese PLA General Hospital. Fifty-five included patients were grouped based on the presence of MS. They accepted the treatment of NB-UVB and the following data were collected: serum levels of IL-17 (interleukin), TNF-α (tumor necrosis factor) and IL-6, Psoriasis Area and Severity Index (PASI) scores before and after 10 sections of NB-UVB treatment.Significant PASI improvement was observed in psoriatic patients without MS after 10 sections of phototherapy, while patients with MS showed a less improvement (P < .001). There was statistically significant difference in percentage of patients achieving 50% reduction in PASI scores between the 2 groups (P < .05). Multivariate logistic regression analysis showed MS was an independent factor that affecting the treatment of NB-UVB (P < .05). Psoriatic patients with MS showed a much less reduction of IL-17 and IL-6 before and after 10 sections of NB-UVB treatment respectively than patients without MS (P < .05).Psoriatic patients with MS have poorer improvement in comparison those without MS using NB-UVB treatment. MS was an independent factor that affecting the treatment of NB-UVB. In addition, psoriatic patients with MS showed a much less reduction of systemic biomarkers (interleukin-IL-17, TNF-α, IL-6) than patients without MS. Namely, they may need a longer course of treatment to achieve improved skin lesions.
[Mh] Termos MeSH primário: Síndrome Metabólica/complicações
Fototerapia
Psoríase/terapia
[Mh] Termos MeSH secundário: Adulto
Biomarcadores/sangue
Feminino
Seres Humanos
Interleucina-17/sangue
Interleucina-6/sangue
Masculino
Psoríase/complicações
[Pt] Tipo de publicação:JOURNAL ARTICLE; OBSERVATIONAL STUDY
[Nm] Nome de substância:
0 (Biomarkers); 0 (Interleukin-17); 0 (Interleukin-6)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180301
[Lr] Data última revisão:
180301
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180203
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000008677



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