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Pesquisa : C19.874.283.300 [Categoria DeCS]
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  1 / 1936 MEDLINE  
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[PMID]:28287203
[Au] Autor:Franzellin F; Lucchin L
[Ad] Endereço:Corresponsabile Campagna Provinciale Iodoprofilassi, Ambulatorio per le Tireopatie, Clinica Villa Melitta, Bolzano.
[Ti] Título:[The iodine prophylaxis: the experience in the Autonomous Province of Bolzano (South Tyrol).]
[Ti] Título:La iodoprofilassi: l'esperienza della Provincia Autonoma di Bolzano (Alto Adige)..
[So] Source:Recenti Prog Med;108(2):90-97, 2017 Feb.
[Is] ISSN:2038-1840
[Cp] País de publicação:Italy
[La] Idioma:ita
[Ab] Resumo:Since ancient times in South Tyrol there was evidence of endemic goitre caused by iodine deficiency. In the early 80's an epidemiological research on adults and primary and secondary school children reported in the least a prevalence of goitre from grade 1 B-3 (WHO) of 23,66% (limits WHO >5%) and an urinary iodine of 10,2 µgI/L. Therefore South Tyrol population presented heavy endemic goitre. In 1982 started a generalized iodine prophylaxis with alimentary iodined salt after an intense prevention campaign. In 1990 it has been done another epidemiological research on primary and secondary school children of the province (neck palpation, thyroid ultrasound, blood and urine tests) which revealed a prevalence of goitre from grade 1 B (WHO) of 1,6% (limits WHO >5%) and an urinary iodine of 137,1 µgI/L. Therefore in South Tyrol there was no more evidence of endemic goitre. In 2001 another research over primary and secondary school children, of the same areas and with the same approaches of the previous researches reported a prevalence of goitre of 1,5% and a median of urinary iodine of 230 µgI/L. On the basis of the data of Istituto Superiore di Sanità (National Institute of Health) can be stated that in the Province of Bolzano there's a low presence of congenital hypothyroidism. It has been observed an increase in the thyroiditis and in the diagnosis of thyroid cancer was marked an accentuation of papillar forms, less aggressive than the follicula. Unfortunately since 2001 no new epidemiological researches were done, due to lack of financial resources and the raising of other sanitary problems of higher priority.
[Mh] Termos MeSH primário: Bócio Endêmico/prevenção & controle
Iodo/administração & dosagem
Cloreto de Sódio na Dieta/administração & dosagem
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Criança
Feminino
Bócio Endêmico/epidemiologia
Seres Humanos
Iodo/deficiência
Itália/epidemiologia
Masculino
Meia-Idade
Prevalência
Neoplasias da Glândula Tireoide/epidemiologia
Tireoidite/epidemiologia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Sodium Chloride, Dietary); 0 (iodized salt); 9679TC07X4 (Iodine)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170922
[Lr] Data última revisão:
170922
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170314
[St] Status:MEDLINE
[do] DOI:10.1701/2636.27100


  2 / 1936 MEDLINE  
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[PMID]:28079353
[Au] Autor:Vanderpas JB; Moreno-Reyes R
[Ad] Endereço:School of Public Health, Free University of Bruxelles, Bruxelles, Belgium - jean.vanderpas@wiv-isp.be.
[Ti] Título:Historical aspects of iodine deficiency control.
[So] Source:Minerva Med;108(2):124-135, 2017 Apr.
[Is] ISSN:1827-1669
[Cp] País de publicação:Italy
[La] Idioma:eng
[Ab] Resumo:In 1895, iodine was characterized as an essential element of thyroid tissue by Baumann. The efficacy of iodine to prevent goiter was demonstrated by Marine in Northern USA in 1916-1920. Severe endemic goiter and cretinism had been almost entirely eliminated from continental Western Europe and Northern America before the 1930's; however large populations elsewhere and even some places in Western Europe (Sicily) were still affected up to the 2000's. Public health consequences of iodine deficiency are not limited to endemic goiter and cretinism. Iodine deficiency disorders include also increased neonatal death rate and decreased intellectual development, although these consequences are not included in the current estimation of the Global Burden Disease related to iodine deficiency. Severe iodine deficiency as a public health problem is now largely under control worldwide, but can still affect isolated places, in hard-to-reach and/or politically neglected populations. We emphasize the importance of maintaining international cooperation efforts, in order to monitor iodine status where iodine deficiency is now adequately controlled, and identify at-risk population where it is not. The goal should be now global eradication of severe iodine deficiency. Commercial distribution of iodized salt remains the most appropriate strategy. A randomized clinical trial in New Guinea clearly showed in the 1970's that correcting severe iodine deficiency early in pregnancy prevents endemic neurological cretinism. This supports the essential role of thyroid hormones of maternal origin on the normal fetal development, during the first trimester of pregnancy (i.e. when fetal thyroid is still not functional). A randomized clinical trial in Congo (RD) in the 1970's also showed that correcting severe iodine deficiency during pregnancy prevents myxœdematous cretinism, particularly prevalent in affected Congolese areas.
[Mh] Termos MeSH primário: Iodo/deficiência
Iodo/história
Oligoelementos/deficiência
[Mh] Termos MeSH secundário: Hipotireoidismo Congênito/história
Erradicação de Doenças/história
Europa (Continente)
Feminino
Saúde Global/história
Saúde Global/estatística & dados numéricos
Bócio Endêmico/história
Bócio Endêmico/prevenção & controle
História do Século XVIII
História do Século XIX
História do Século XX
História do Século XXI
Seres Humanos
Lactente
Mortalidade Infantil
Iodo/provisão & distribuição
Nova Guiné
Gravidez
Prevalência
Ensaios Clínicos Controlados Aleatórios como Assunto
Cloreto de Sódio na Dieta/provisão & distribuição
Oligoelementos/história
Estados Unidos
[Pt] Tipo de publicação:HISTORICAL ARTICLE; JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Sodium Chloride, Dietary); 0 (Trace Elements); 0 (iodized salt); 9679TC07X4 (Iodine)
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170224
[Lr] Data última revisão:
170224
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170113
[St] Status:MEDLINE
[do] DOI:10.23736/S0026-4806.17.04884-4


  3 / 1936 MEDLINE  
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[PMID]:28079352
[Au] Autor:Olivieri A; DI Cosmo C; DE Angelis S; DA Cas R; Stacchini P; Pastorelli A; Vitti P; Regional Observatories for Goiter Prevention
[Ad] Endereço:Endocrinology and Metabolism Unit, Department of Cell Biology and Neuroscience, Italian National Institute of Health, Rome, Italy - antonella.olivieri@iss.it.
[Ti] Título:The way forward in Italy for iodine.
[So] Source:Minerva Med;108(2):159-168, 2017 Apr.
[Is] ISSN:1827-1669
[Cp] País de publicação:Italy
[La] Idioma:eng
[Ab] Resumo:Italy is dealing with iodine deficiency since ancient times. In 1848 an ad hoc committee appointed by the king of Sardinia, identified extensive areas afflicted by endemic goiter and endemic cretinism in Piedmont, Liguria and Sardinia. Since then many epidemiological studies have been conducted in our country. These showed that iodine deficiency was present not only in mountain areas but also in coastal areas. In 1972 the iodization of salt at 15 mg/kg was allowed by law and iodized salt was distributed on request to selected endemic areas. Five years later the distribution was extended to the whole country. However the sale of iodized salt was not mandatory at that time and only a small fraction of the Italian population started using iodized salt. In 1991 the content of iodine in the salt was raised to 30 mg/kg and in 2005 a nationwide salt iodization program was finally implemented. Some years later a nationwide monitoring program of iodine prophylaxis was also implemented. Since 2005 the sale of iodized salt in Italian supermarkets has increased (34% in 2006, 55% in 2012), although it has been observed that the use of iodized salt is still low in the communal eating areas and in the food industry. These data are coherent with recent epidemiological studies showing that some regions in our country are still characterized by mild iodine deficiency and a high frequency of goiter and other iodine deficiency disorders. This implies that further efforts should be made to successfully correct iodine deficiency in Italy.
[Mh] Termos MeSH primário: Hipotireoidismo Congênito/epidemiologia
Bócio Endêmico/epidemiologia
Iodo/deficiência
Cloreto de Sódio na Dieta/provisão & distribuição
Oligoelementos/deficiência
[Mh] Termos MeSH secundário: Hipotireoidismo Congênito/prevenção & controle
Bócio Endêmico/prevenção & controle
Seres Humanos
Iodo/administração & dosagem
Iodo/provisão & distribuição
Itália/epidemiologia
Desenvolvimento de Programas
Cloreto de Sódio na Dieta/administração & dosagem
Oligoelementos/administração & dosagem
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Sodium Chloride, Dietary); 0 (Trace Elements); 0 (iodized salt); 9679TC07X4 (Iodine)
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170727
[Lr] Data última revisão:
170727
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170113
[St] Status:MEDLINE
[do] DOI:10.23736/S0026-4806.17.04877-7


  4 / 1936 MEDLINE  
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[PMID]:28001012
[Au] Autor:Manousou S; Dahl L; Heinsbaek Thuesen B; Hulthén L; Nyström Filipsson H
[Ad] Endereço:Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
[Ti] Título:Iodine deficiency and nutrition in Scandinavia.
[So] Source:Minerva Med;108(2):147-158, 2017 Apr.
[Is] ISSN:1827-1669
[Cp] País de publicação:Italy
[La] Idioma:eng
[Ab] Resumo:Iodine nutrition is a result of geological conditions, iodine fortification and monitoring strategies within a country together with the dietary habits of the population. This review summarizes the basis for the current iodine situation in the Scandinavian countries in order to identify gaps in knowledge, determine necessary future steps, highlight landmarks in Scandinavian iodine research and consider ongoing studies in Scandinavian countries with high international impact. Historically, iodine deficiency disorders such as goiter were common in Norway and Sweden, but not in Denmark. Different strategies have been used in Scandinavia to improve iodine nutrition. The major source of iodine is iodized salt in Sweden and from milk and dairy products in Norway. In Denmark, drinking water, milk, dairy products and iodized salt used in commercial production of bread are the important sources of iodine. The current iodine status in Scandinavia is not optimal and action is ongoing to increase iodination in Denmark, where there is mild iodine deficiency in the general population. Data from all three countries indicate insufficient iodine nutrition during pregnancy and there is a need for data from children, adolescents and young women. Monitoring a population's iodine status and dietary iodine sources is necessary to secure iodine nutrition in Scandinavia. Ongoing studies in Scandinavia will contribute significantly to the knowledge about the effects of mild to moderate iodine deficiency.
[Mh] Termos MeSH primário: Suplementos Nutricionais
Iodo/administração & dosagem
Iodo/deficiência
Oligoelementos/administração & dosagem
Oligoelementos/deficiência
[Mh] Termos MeSH secundário: Adolescente
Adulto
Criança
Dinamarca/epidemiologia
Feminino
Geografia Médica
Bócio Endêmico/epidemiologia
Bócio Endêmico/prevenção & controle
Seres Humanos
Iodo/urina
Masculino
Noruega/epidemiologia
Gravidez
Fatores Sexuais
Cloreto de Sódio na Dieta/administração & dosagem
Suécia/epidemiologia
Oligoelementos/urina
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Sodium Chloride, Dietary); 0 (Trace Elements); 0 (iodized salt); 9679TC07X4 (Iodine)
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170224
[Lr] Data última revisão:
170224
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161222
[St] Status:MEDLINE
[do] DOI:10.23736/S0026-4806.16.04849-7


  5 / 1936 MEDLINE  
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[PMID]:27619197
[Au] Autor:Bates AJ; Cetto R; Doorly DJ; Schroter RC; Tolley NS; Comerford A
[Ad] Endereço:Department of Aeronautics, Imperial College London, United Kingdom. Electronic address: a.bates11@imperial.ac.uk.
[Ti] Título:The effects of curvature and constriction on airflow and energy loss in pathological tracheas.
[So] Source:Respir Physiol Neurobiol;234:69-78, 2016 Dec.
[Is] ISSN:1878-1519
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:This paper considers factors that play a significant role in determining inspiratory pressure and energy losses in the human trachea. Previous characterisations of pathological geometry changes have focussed on relating airway constriction and subsequent pressure loss, however many pathologies that affect the trachea cause deviation, increased curvature, constriction or a combination of these. This study investigates the effects of these measures on tracheal flow mechanics, using the compressive goitre (a thyroid gland enlargement) as an example. Computational fluid dynamics simulations were performed in airways affected by goitres (with differing geometric consequences) and a normal geometry for comparison. Realistic airways, derived from medical images, were used because idealised geometries often oversimplify the complex anatomy of the larynx and its effects on the flow. Two mechanisms, distinct from stenosis, were found to strongly affect airflow energy dissipation in the pathological tracheas. The jet emanating from the glottis displayed different impingement and breakdown patterns in pathological geometries and increased loss was associated with curvature.
[Mh] Termos MeSH primário: Resistência das Vias Respiratórias/fisiologia
Metabolismo Energético/fisiologia
Modelos Biológicos
Mecânica Respiratória/fisiologia
Traqueia/fisiopatologia
[Mh] Termos MeSH secundário: Simulação por Computador
Constrição
Bócio Endêmico/patologia
Seres Humanos
Hidrodinâmica
Ventilação Pulmonar
Traqueia/patologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170925
[Lr] Data última revisão:
170925
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160914
[St] Status:MEDLINE


  6 / 1936 MEDLINE  
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[PMID]:27571216
[Au] Autor:Hanley P; Lord K; Bauer AJ
[Ad] Endereço:The Thyroid Center, Division of Endocrinology and Diabetes, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania2Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia.
[Ti] Título:Thyroid Disorders in Children and Adolescents: A Review.
[So] Source:JAMA Pediatr;170(10):1008-1019, 2016 Oct 01.
[Is] ISSN:2168-6211
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Importance: Normal thyroid gland function is critical for early neurocognitive development, as well as for growth and development throughout childhood and adolescence. Thyroid disorders are common, and attention to physical examination findings, combined with selected laboratory and radiologic tools, aids in the early diagnosis and treatment. Objective: To provide a practical review of the presentation, evaluation, and treatment of thyroid disorders commonly encountered in a primary care practice. Evidence Review: We performed a literature review using the PubMed database. Results focused on reviews and articles published from January 1, 2010, through December 31, 2015. Articles published earlier than 2010 were included when appropriate for historical perspective. Our review emphasized evidence-based management practices for the clinician, as well as consensus statements and guidelines. A total of 479 articles for critical review were selected based on their relevance to the incidence, pathophysiology, laboratory evaluation, radiological assessment, and treatment of hypothyroidism, hyperthyroidism, thyroid nodules, and thyroid cancer in children and adolescents. Eighty-three publications were selected for inclusion in this article based on their relevance to these topics. Findings: The primary care physician is often the first health care professional responsible for initiating the evaluation of a thyroid disorder in children and adolescents. Patients may be referred secondary to an abnormal newborn screening, self-referred after a caregiver raises concern, or identified to be at risk of a thyroid disorder based on findings from a routine well-child visit. Irrespective of the path of referral, knowledge of the signs and symptoms of hypothyroidism, hyperthyroidism, and thyroid nodules, as well as the general approach to evaluation and management, will help the primary care physician complete an initial assessment and determine which patients would benefit from referral to a pediatric endocrinologist. Conclusions and Relevance: Early identification and treatment of thyroid disease in children and adolescents is critical to optimize growth and development. The primary care physician plays a critical role in identifying patients at risk. An understanding of risk factors, clinical signs and symptoms, and interpretation of screening laboratories ensures an efficient and accurate diagnosis of these common disorders. Regular communication between the primary care physician and the subspecialist is critical to optimize outcome because the majority of patients with thyroid disorders will require long-term to lifelong medical therapy and/or surveillance.
[Mh] Termos MeSH primário: Saúde do Adolescente
Saúde da Criança
Doenças da Glândula Tireoide/diagnóstico
Doenças da Glândula Tireoide/terapia
[Mh] Termos MeSH secundário: Adolescente
Criança
Hipotireoidismo Congênito/diagnóstico
Hipotireoidismo Congênito/terapia
Feminino
Bócio Endêmico/diagnóstico
Bócio Endêmico/terapia
Seres Humanos
Hipertireoidismo/diagnóstico
Hipertireoidismo/terapia
Hipotireoidismo/diagnóstico
Hipotireoidismo/terapia
Masculino
Fatores de Risco
Testes de Função Tireóidea
Neoplasias da Glândula Tireoide/diagnóstico
Neoplasias da Glândula Tireoide/terapia
Tireoidite Autoimune/diagnóstico
Tireoidite Autoimune/terapia
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170529
[Lr] Data última revisão:
170529
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:160830
[St] Status:MEDLINE
[do] DOI:10.1001/jamapediatrics.2016.0486


  7 / 1936 MEDLINE  
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[PMID]:27483638
[Au] Autor:Flemmer A
[Ti] Título:[Iodized salt as a supplement - necessary or not?].
[Ti] Título:Jodsalz als Supplement--nötig oder nicht?.
[So] Source:Kinderkrankenschwester;35(6):205-8, 2016 Jun.
[Is] ISSN:0723-2276
[Cp] País de publicação:Germany
[La] Idioma:ger
[Mh] Termos MeSH primário: Suplementos Nutricionais
Bócio Endêmico/enfermagem
Bócio Endêmico/prevenção & controle
Iodo/administração & dosagem
Necessidades Nutricionais
Iodeto de Potássio/administração & dosagem
Cloreto de Sódio na Dieta/administração & dosagem
[Mh] Termos MeSH secundário: Adulto
Criança
Alemanha
Seres Humanos
Iodo/deficiência
Iodo/fisiologia
Hormônios Tireóideos/fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Sodium Chloride, Dietary); 0 (Thyroid Hormones); 0 (iodized salt); 1C4QK22F9J (Potassium Iodide); 9679TC07X4 (Iodine)
[Em] Mês de entrada:1609
[Cu] Atualização por classe:161020
[Lr] Data última revisão:
161020
[Sb] Subgrupo de revista:N
[Da] Data de entrada para processamento:160804
[St] Status:MEDLINE


  8 / 1936 MEDLINE  
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[PMID]:27438852
[Au] Autor:Zmitek K; Pravst I
[Ad] Endereço:Nutrition Institute, Trzaska cesta 40, Ljubljana SI-1000, Slovenia. katja.zmitek@vist.si.
[Ti] Título:Iodisation of Salt in Slovenia: Increased Availability of Non-Iodised Salt in the Food Supply.
[So] Source:Nutrients;8(7), 2016 Jul 16.
[Is] ISSN:2072-6643
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:Salt iodisation is considered a key public health measure for assuring adequate iodine intake in iodine-deficient countries. In Slovenia, the iodisation of all salt was made mandatory in 1953. A considerable regulatory change came in 2003 with the mandatory iodisation of rock and evaporated salt only. In addition, joining the European Union's free single market in 2004 enabled the import of non-iodised salt. The objective of this study was to investigate the extent of salt iodising in the food supply. We examined both the availability and sale of (non-)iodised salt. Average sales-weighted iodine levels in salt were calculated using the results of a national monitoring of salt quality. Data on the availability and sales of salts were collected in major food retailers in 2014. Iodised salt represented 59.2% of the salt samples, and 95.9% of salt sales, with an average (sales-weighted) level of 24.2 mg KI/kg of salt. The average sales-weighted KI level in non-iodised salts was 3.5 mg KI/kg. We may conclude that the sales-weighted average iodine levels in iodised salt are in line with the regulatory requirements. However, the regulatory changes and the EU single market have considerably affected the availability of non-iodised salt. While sales of non-iodised salt are still low, non-iodised salt represented 33.7% of the salts in our sample. This indicates the existence of a niche market which could pose a risk of inadequate iodine intake in those who deliberately decide to consume non-iodised salt only. Policymakers need to provide efficient salt iodisation intervention to assure sufficient iodine supply in the future. The reported sales-weighting approach enables cost-efficient monitoring of the iodisation of salt in the food supply.
[Mh] Termos MeSH primário: Deficiências Nutricionais/prevenção & controle
Abastecimento de Alimentos
Iodo/deficiência
Política Nutricional
Cloreto de Sódio na Dieta/efeitos adversos
[Mh] Termos MeSH secundário: Bases de Dados Factuais
Deficiências Nutricionais/epidemiologia
Deficiências Nutricionais/etiologia
Deficiências Nutricionais/fisiopatologia
União Europeia
Rotulagem de Alimentos
Abastecimento de Alimentos/economia
Bócio Endêmico/epidemiologia
Bócio Endêmico/etiologia
Bócio Endêmico/prevenção & controle
Promoção da Saúde
Seres Humanos
Iodo/análise
Iodo/química
Iodo/economia
Iodo/uso terapêutico
Cooperação do Paciente
Iodeto de Potássio/análise
Iodeto de Potássio/economia
Iodeto de Potássio/uso terapêutico
Eslovênia/epidemiologia
Cloreto de Sódio na Dieta/análise
Cloreto de Sódio na Dieta/economia
Cloreto de Sódio na Dieta/uso terapêutico
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Sodium Chloride, Dietary); 0 (iodized salt); 1C4QK22F9J (Potassium Iodide); 9679TC07X4 (Iodine)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170317
[Lr] Data última revisão:
170317
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160721
[St] Status:MEDLINE


  9 / 1936 MEDLINE  
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[PMID]:26260217
[Au] Autor:Trimarchi F; Russo G
[Ad] Endereço:Dipartimento di Medicina Clinica e Sperimentale, University of Messina, Messina, Italy. francesco.trimarchi@unime.it.
[Ti] Título:Antonello da Messina: Virgin Annunciate.
[So] Source:J Endocrinol Invest;39(2):257-8, 2016 Feb.
[Is] ISSN:1720-8386
[Cp] País de publicação:Italy
[La] Idioma:eng
[Mh] Termos MeSH primário: Bócio Endêmico/história
Medicina nas Artes
Glândula Tireoide/patologia
[Mh] Termos MeSH secundário: Adolescente
Catolicismo
Feminino
Bócio Endêmico/patologia
Bócio Endêmico/fisiopatologia
História do Século XV
Seres Humanos
Pinturas
Retratos como Assunto
Sicília
[Pt] Tipo de publicação:HISTORICAL ARTICLE; JOURNAL ARTICLE
[Em] Mês de entrada:1610
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150812
[St] Status:MEDLINE
[do] DOI:10.1007/s40618-015-0359-7


  10 / 1936 MEDLINE  
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[PMID]:26066526
[Au] Autor:Manjunath B; Suman G; Hemanth T; Shivaraj NS; Murthy NS
[Ad] Endereço:M. S. Ramaiah Medical College, Bangalore, Karnataka, India. bhanumuula@gmail.com.
[Ti] Título:Prevalence and Factors Associated with Goitre among 6-12-year-old Children in a Rural Area of Karnataka in South India.
[So] Source:Biol Trace Elem Res;169(1):22-6, 2016 Jan.
[Is] ISSN:1559-0720
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:In India, endemic goitre is present in sub-Himalayan region and in pockets in states of Andhra Pradesh, Karnataka and Gujarat. Being a public health problem amenable for prevention, the assessment of prevalence of endemic goitre in an area helps in understanding whether the preventive strategies under National Iodine Deficiency Disorder Control Program (NIDDCP) have any impact on the control of endemic goitre. Hence, the current study was carried out to determine the prevalence, distribution and factors associated with iodine deficiency goitre among 6-12-year-old children in a rural area in south Karnataka. A cross-sectional study was conducted among 838 children, using a questionnaire adopted from Iodized Salt Program Assessment Tool and the tools prescribed by WHO for goitre survey. The prevalence of goitre in the study area was 21.9% (95% CI 19.2-24.8). There was higher prevalence of goitre among those having salt iodine <15 ppm than those with >15 ppm (P = 0.01; OR 1.59; 95% CI 1.10-2.29). In 10% of the children, urinary iodine excretion (UIE) was assessed and prevalence was higher among those with <100 µg/l of UIE than those with normal UIE, which was not statistically significant (P = 0.8, OR 1.36; 95% CI 0.62-2.96). Multiple logistic regression revealed that gender (P = 0.002; OR 1.7; 95% CI 1.21-2.35) was an independent variable associated with goitre. The study area was found to be moderately endemic for goitre based on the WHO criteria. Higher prevalence of goitre was found to be still associated with consumption of low iodized salt (<15 ppm) necessitating emphasis on monitoring of salt iodine levels in the study area. Though NIDDCP is being implemented since five decades in India, the burden of iodine deficiency disorders (IDDs) is still high demanding further impetus to the monitoring systems of the programme.
[Mh] Termos MeSH primário: Bócio Endêmico/epidemiologia
[Mh] Termos MeSH secundário: Criança
Estudos Transversais
Feminino
Seres Humanos
Índia/epidemiologia
Iodo
Masculino
Prevalência
Saúde Pública
Fatores de Risco
Cloreto de Sódio na Dieta
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Sodium Chloride, Dietary); 0 (iodized salt); 9679TC07X4 (Iodine)
[Em] Mês de entrada:1609
[Cu] Atualização por classe:151223
[Lr] Data última revisão:
151223
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150613
[St] Status:MEDLINE
[do] DOI:10.1007/s12011-015-0398-0



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