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Pesquisa : C19.874.397.685.905 [Categoria DeCS]
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[PMID]:29443784
[Au] Autor:Namatame C; Sonoo T; Fukushima K; Naraba H; Hashimoto H; Nakamura K
[Ad] Endereço:Department of Emergency and Critical Care Medicine, Hitachi General Hospital, Johnan-cho, Hitachi, Ibaraki, Japan.
[Ti] Título:A thyroid storm patient with protracted disturbance of consciousness and reversible lesion in the splenium of corpus callosum: A case report.
[So] Source:Medicine (Baltimore);97(7):e9949, 2018 Feb.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:RATIONALE: Various neurological manifestations are observed in thyroid storm patients but protracted disturbance of consciousness is rare. PATIENT CONCERNS: A 58-year-old male was admitted to our hospital after a traffic accident. DIAGNOSES: Although awake on arrival, he fell into coma after admission. Based on the clinical symptoms and hyperthyroidism, the patient was diagnosed with thyroid storm (TS). INTERVENTIONS: Even after improvement of hyperthyroidism, disturbance of consciousness was protracted. Considering the possibility of immune-related etiology, methylprednisolone pulse was started. OUTCOMES: His consciousness level improved over a 3-month period, and he became able to walk with some assistance after 6 months. LESSONS: His condition was atypical of TS-associated encephalopathy because of the long clinical course. Reversible splenial lesion was visible using brain imaging. In some cases of TS, disturbance of consciousness can be protracted for several months, but it is reversible. Therefore, it is necessary to judge the long-term neurological outcome carefully.
[Mh] Termos MeSH primário: Coma/etiologia
Corpo Caloso/diagnóstico por imagem
Crise Tireóidea/complicações
Crise Tireóidea/diagnóstico por imagem
[Mh] Termos MeSH secundário: Acidentes de Trânsito
Coma/diagnóstico por imagem
Glucocorticoides/uso terapêutico
Seres Humanos
Hipertireoidismo/complicações
Hipertireoidismo/tratamento farmacológico
Imagem por Ressonância Magnética
Masculino
Metilprednisolona/uso terapêutico
Meia-Idade
Crise Tireóidea/tratamento farmacológico
Resultado do Tratamento
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Glucocorticoids); X4W7ZR7023 (Methylprednisolone)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180220
[Lr] Data última revisão:
180220
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180215
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000009949


  2 / 770 MEDLINE  
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[PMID]:28864374
[Au] Autor:Mohananey D; Smilowitz N; Villablanca PA; Bhatia N; Agrawal S; Baruah A; Ali MS; Bangalore S; Ramakrishna H
[Ad] Endereço:Division of Hospital Medicine, Cleveland Clinic, Cleveland, Ohio. Electronic address: mohanad@ccf.org.
[Ti] Título:Trends in the Incidence and In-Hospital Outcomes of Cardiogenic Shock Complicating Thyroid Storm.
[So] Source:Am J Med Sci;354(2):159-164, 2017 Aug.
[Is] ISSN:1538-2990
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Thyroid storm (TS) constitutes an endocrine emergency with an incidence of up to 10% of all admissions for thyrotoxicosis. Cardiogenic shock (CS) is a rare complication of TS and very limited data exists on its incidence and outcomes. We aimed to estimate the national trends in incidence and outcomes of CS among patients admitted to US hospitals with TS. MATERIALS AND METHODS: We queried the nationwide inpatient sample for patients with the discharge diagnosis of TS between the years of 2003 and 2011. RESULTS: Based on a weighted estimate, we identified 41,835 patients with a diagnosis of TS, of which 1% developed CS. Patients with CS were more likely to have history of atrial fibrillation, alcohol abuse, preexisting congestive heart failure, coagulopathy, drug use, liver disease, pulmonary circulation disorders, valvular disorders, weight loss, renal failure, fluid and electrolyte disorders as compared to those who did not develop CS (P < 0.001 for all). We observed an increase in incidence of CS from 0.5% in 2003 to 3% in 2011 and a decrease in mortality from 60.5% in 2003 to 20.9% in 2011 (P < 0.001 for both). CONCLUSIONS: We observed that CS is a rare complication of TS, which occurs more commonly in male patients with preexisting structural and atherosclerotic heart disease, and carries a very poor prognosis. Although incidence has increased over the years, mortality from CS has steadily declined.
[Mh] Termos MeSH primário: Choque Cardiogênico/epidemiologia
Choque Cardiogênico/etiologia
Crise Tireóidea/complicações
Crise Tireóidea/epidemiologia
[Mh] Termos MeSH secundário: Adulto
Idoso
Feminino
Mortalidade Hospitalar
Hospitalização
Seres Humanos
Incidência
Masculino
Meia-Idade
Prognóstico
Choque Cardiogênico/diagnóstico
Choque Cardiogênico/mortalidade
Crise Tireóidea/diagnóstico
Crise Tireóidea/mortalidade
Estados Unidos/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170908
[Lr] Data última revisão:
170908
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170903
[St] Status:MEDLINE


  3 / 770 MEDLINE  
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[PMID]:28562568
[Au] Autor:Kiriyama H; Amiya E; Hatano M; Hosoya Y; Maki H; Nitta D; Saito A; Shiraishi Y; Minatsuki S; Sato T; Murakami H; Uehara M; Manaka K; Makita N; Watanabe M; Komuro I
[Ad] Endereço:aDepartment of Cardiovascular Medicine bDepartment of Therapeutic Strategy for Heart Failure cDepartment of Endocrinology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
[Ti] Título:Rapid Improvement of thyroid storm-related hemodynamic collapse by aggressive anti-thyroid therapy including steroid pulse: A case report.
[So] Source:Medicine (Baltimore);96(22):e7053, 2017 Jun.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:RATIONALE: Heart failure is relatively common in patients with hyperthyroidism, but thyrotoxic cardiomyopathy with poor left ventricular (LV) systolic function is very rare. PATIENT CONCERNS: We experienced a representative case of a patient who presented with severe LV dysfunction related to thyroid storm and needed extracorporeal membrane oxygenation (ECMO) temporally. DIAGNOSIS: Thyrotoxic cardiomyopathy. INTERVENTIONS AND OUTCOMES: Aggressive antithyroid therapy, including steroid pulse to hyperthyroidism, leads to the dramatic improvement of cardiac function and she was successfully weaned from ECMO. LESSONS: The most outstanding feature of the current case was the rapid decrease of cardiac injury and improvement of cardiac function by strengthening antithyroid therapy, including steroid pulse, without thyroid hormone level normalization. In thyroid storm, various systemic inflammatory reactions have different time courses and among them, the cardiac phenotype emerges in most striking and critical ways.
[Mh] Termos MeSH primário: Antitireóideos/uso terapêutico
Esteroides/uso terapêutico
Crise Tireóidea/complicações
Crise Tireóidea/tratamento farmacológico
Disfunção Ventricular Esquerda/tratamento farmacológico
Disfunção Ventricular Esquerda/etiologia
[Mh] Termos MeSH secundário: Feminino
Seres Humanos
Meia-Idade
Crise Tireóidea/diagnóstico por imagem
Crise Tireóidea/fisiopatologia
Disfunção Ventricular Esquerda/diagnóstico por imagem
Disfunção Ventricular Esquerda/fisiopatologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antithyroid Agents); 0 (Steroids)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170630
[Lr] Data última revisão:
170630
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170601
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000007053


  4 / 770 MEDLINE  
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[PMID]:28228636
[Au] Autor:Tanabe N; Hiraoka E; Hoshino M; Deshpande GA; Sawada K; Norisue Y; Tsukuda J; Suzuki T
[Ad] Endereço:Department of Internal Medicine, Tokyo Bay Urayasu Ichikawa Medical Center, Urayasu, Chiba, Japan.
[Ti] Título:Progressive Ischemic Stroke due to Thyroid Storm-Associated Cerebral Venous Thrombosis.
[So] Source:Am J Case Rep;18:194-197, 2017 Feb 23.
[Is] ISSN:1941-5923
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND Cerebral venous thrombosis (CVT) is a rare but fatal complication of hyperthyroidism that is induced by the hypercoagulable state of thyrotoxicosis. Although it is frequently difficult to diagnose CVT promptly, it is important to consider it in the differential diagnosis when a hyperthyroid patient presents with atypical neurologic symptoms. CASE REPORT A 49-year-old Japanese female with unremarkable medical history came in with thyroid storm and multiple progressive ischemic stroke identified at another hospital. Treatment for thyroid storm with beta-blocker, glucocorticoid, and potassium iodide-iodine was started and MR venography was performed on hospital day 3 for further evaluation of her progressive ischemic stroke. The MRI showed CVT, and anticoagulation therapy, in addition to the anti-thyroid agents, was initiated. The patient's thyroid function was successfully stabilized by hospital day 10 and further progression of CVT was prevented. CONCLUSIONS Physicians should consider CVT when a patient presents with atypical course of stroke or with atypical MRI findings such as high intensity area in apparent diffusion coefficient (ADC) mapping. Not only is an early diagnosis and initiation of anticoagulation important, but identifying and treating the underlying disease is essential to avoid the progression of CVT.
[Mh] Termos MeSH primário: Isquemia Encefálica/etiologia
Hipertireoidismo/complicações
Trombose Intracraniana/etiologia
Veias Jugulares
Trombose do Seio Lateral
Acidente Vascular Cerebral/etiologia
Crise Tireóidea/etiologia
Trombose Venosa/etiologia
[Mh] Termos MeSH secundário: Antagonistas Adrenérgicos beta/uso terapêutico
Anticoagulantes/uso terapêutico
Isquemia Encefálica/diagnóstico
Quimioterapia Combinada
Feminino
Glucocorticoides/uso terapêutico
Heparina/uso terapêutico
Seres Humanos
Trombose Intracraniana/diagnóstico
Trombose Intracraniana/tratamento farmacológico
Meia-Idade
Iodeto de Potássio/uso terapêutico
Acidente Vascular Cerebral/diagnóstico
Acidente Vascular Cerebral/tratamento farmacológico
Crise Tireóidea/diagnóstico
Resultado do Tratamento
Trombose Venosa/diagnóstico
Trombose Venosa/tratamento farmacológico
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Adrenergic beta-Antagonists); 0 (Anticoagulants); 0 (Glucocorticoids); 1C4QK22F9J (Potassium Iodide); 9005-49-6 (Heparin)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170320
[Lr] Data última revisão:
170320
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170224
[St] Status:MEDLINE


  5 / 770 MEDLINE  
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[PMID]:28090049
[Au] Autor:Ikeoka T; Otsuka H; Fujita N; Masuda Y; Maeda S; Horie I; Ando T; Abiru N; Kawakami A
[Ad] Endereço:Department of Endocrinology and Metabolism, National Hospital Organization Nagasaki Medical Center, Japan.
[Ti] Título:Thyroid Storm Precipitated by Diabetic Ketoacidosis and Influenza A: A Case Report and Literature Review.
[So] Source:Intern Med;56(2):181-185, 2017.
[Is] ISSN:1349-7235
[Cp] País de publicação:Japan
[La] Idioma:eng
[Ab] Resumo:A 46-year-old woman with a history of Graves' disease presented with the chief complaints of appetite loss, weight loss, fatigue, nausea, and sweating. She was diagnosed with diabetic ketoacidosis (DKA), thyroid storm, and influenza A. She was treated with an intravenous insulin drip, intravenous fluid therapy, intravenous hydrocortisone, oral potassium iodine, and oral methimazole. As methimazole-induced neutropenia was suspected, the patient underwent thyroidectomy. It is important to maintain awareness that thyroid storm and DKA can coexist. Furthermore, even patients who have relatively preserved insulin secretion can develop DKA if thyroid storm and infection develop simultaneously.
[Mh] Termos MeSH primário: Cetoacidose Diabética/diagnóstico
Doença de Graves
Influenza Humana/diagnóstico
Crise Tireóidea/diagnóstico
[Mh] Termos MeSH secundário: Administração Oral
Antitireóideos/administração & dosagem
Cetoacidose Diabética/sangue
Cetoacidose Diabética/complicações
Cetoacidose Diabética/tratamento farmacológico
Diagnóstico Diferencial
Feminino
Hidratação
Seres Humanos
Influenza Humana/sangue
Influenza Humana/complicações
Infusões Intravenosas
Insulina/administração & dosagem
Metimazol/administração & dosagem
Meia-Idade
Crise Tireóidea/sangue
Crise Tireóidea/complicações
Crise Tireóidea/tratamento farmacológico
Tireoidectomia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antithyroid Agents); 0 (Insulin); 554Z48XN5E (Methimazole)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170117
[St] Status:MEDLINE
[do] DOI:10.2169/internalmedicine.56.7593


  6 / 770 MEDLINE  
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[PMID]:28008703
[Au] Autor:Sano M; Homma T; Ishige T; Sawada N; Ihara S; Kinoshita K; Masuda S; Hao H
[Ad] Endereço:Department of Pathology, Nihon University School of Medicine, Itabashi-ku, Tokyo, Japan.
[Ti] Título:An autopsy case of hyperthyroid cardiomyopathy manifesting lethal congestive heart failure.
[So] Source:Pathol Int;67(2):110-112, 2017 Feb.
[Is] ISSN:1440-1827
[Cp] País de publicação:Australia
[La] Idioma:eng
[Mh] Termos MeSH primário: Doença de Graves/complicações
Insuficiência Cardíaca/etiologia
Crise Tireóidea/complicações
[Mh] Termos MeSH secundário: Autopsia
Evolução Fatal
Doença de Graves/patologia
Insuficiência Cardíaca/patologia
Seres Humanos
Masculino
Meia-Idade
Crise Tireóidea/patologia
[Pt] Tipo de publicação:CASE REPORTS; LETTER
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170317
[Lr] Data última revisão:
170317
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161224
[St] Status:MEDLINE
[do] DOI:10.1111/pin.12491


  7 / 770 MEDLINE  
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[PMID]:28008586
[Au] Autor:Park S; Kim TY; Sim S; Oh HS; Song E; Kim M; Kwon H; Choi YM; Jeon MJ; Kim WG; Shong YK; Kim WB
[Ad] Endereço:Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Korea.
[Ti] Título:Association of KCNJ2 Genetic Variants with Susceptibility to Thyrotoxic Periodic Paralysis in Patients with Graves' Disease.
[So] Source:Exp Clin Endocrinol Diabetes;125(2):75-78, 2017 Feb.
[Is] ISSN:1439-3646
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:Thyrotoxic periodic paralysis (TPP) is characterized by acute onset paralysis and hypokalemia predominantly in male patients with thyrotoxicosis. Recent studies have emphasized the importance of potassium channels, which might explain the underlying mechanism of TPP. The gene encodes the inward-rectifying potassium channel. In this study, we evaluated the role of in the development of TPP. Case-control analysis of genetic association with TPP. 83 male patients with Graves' disease (GD) were recruited for this study; 43 patients had TPP, whereas 40 patients had no history of TPP. We analyzed the genotype and allelic frequency of a single-nucleotide polymorphism (SNP; rs312691) (C>T) adjacent to the gene that is known to be related to TPP development. The frequency of the CC genotype of the rs312691 SNP was 0.51 in TPP patients and 0.05 in controls ( value=6.18×10 ). The C allele frequency of the SNP was 0.67 in the TPP group and 0.38 in the control group (odds ratio 3.24; 95% confidence interval 1.65-6.51; value, 3.1×10 ). The rs312691 SNP was significantly associated with TPP. We demonstrated that the rs312691 SNP was significantly associated with TPP. These findings suggest that plays an important role in the pathophysiology of TPP in Korean GD patients with TPP.
[Mh] Termos MeSH primário: Alelos
Predisposição Genética para Doença
Doença de Graves/genética
Polimorfismo de Nucleotídeo Único
Canais de Potássio Corretores do Fluxo de Internalização/genética
Crise Tireóidea/genética
[Mh] Termos MeSH secundário: Adulto
Grupo com Ancestrais do Continente Asiático
Seres Humanos
Masculino
República da Coreia
[Pt] Tipo de publicação:CLINICAL TRIAL; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (KCNJ2 protein, human); 0 (Potassium Channels, Inwardly Rectifying)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170317
[Lr] Data última revisão:
170317
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161224
[St] Status:MEDLINE
[do] DOI:10.1055/s-0042-119527


  8 / 770 MEDLINE  
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[PMID]:27742400
[Au] Autor:Wang HI; Yiang GT; Hsu CW; Wang JC; Lee CH; Chen YL
[Ad] Endereço:Department of Emergency Medicine, Taichung Armed Forces General Hospital, Taichung, Taiwan.
[Ti] Título:Thyroid Storm in a Patient with Trauma - A Challenging Diagnosis for the Emergency Physician: Case Report and Literature Review.
[So] Source:J Emerg Med;52(3):292-298, 2017 Mar.
[Is] ISSN:0736-4679
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Thyroid storm, an endocrine emergency, remains a diagnostic and therapeutic challenge. It is recognized to develop as a result of several factors, including infection, surgery, acute illness, and rarely, trauma. Recognition of thyroid storm in a trauma patient is difficult because the emergency physician usually focuses on managing more obvious injuries. OBJECTIVE OF THE REVIEW: We present a case of trauma-related thyroid storm and review the previous literature on posttraumatic thyroid storm to delineate risk factors of the disease. The case occurred in a 32-year-old man after a motorcycle accident. DISCUSSION: Careful investigation of patient history and risk factors of trauma-related thyroid storms and utilization of the scoring system may facilitate early diagnosis. Traumatically induced thyroid storm usually responds to medical treatment developed for hyperthyroidism. Surgical intervention may be needed for patients who failed medical treatment or those with direct thyroid gland injuries. The outcome is usually fair under appropriate management. CONCLUSION: We present a case of trauma-related thyroid storm to illustrate the diagnostic and therapeutic approach with a summary of the previous literature. Emergency physicians should be aware of the clinical presentation and risk factors of patients with trauma-related thyroid storm to reduce the rate of misdiagnosis and prevent catastrophic outcomes.
[Mh] Termos MeSH primário: Hipertireoidismo/complicações
Crise Tireóidea/diagnóstico
Crise Tireóidea/etiologia
Ferimentos e Lesões/complicações
[Mh] Termos MeSH secundário: Adulto
Diafragma/anormalidades
Serviço Hospitalar de Emergência/organização & administração
Seres Humanos
Hipertireoidismo/terapia
Masculino
Fatores de Risco
Taquicardia/etiologia
Taquipneia/etiologia
Testes de Função Tireóidea
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171102
[Lr] Data última revisão:
171102
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161016
[St] Status:MEDLINE


  9 / 770 MEDLINE  
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[PMID]:27828704
[Au] Autor:Yang K; Adada MM; Sherman MJ; Yel I; Alam A
[Ad] Endereço:Stony Brook School of Medicine, Stony Brook, New York, USA.
[Ti] Título:Thyroid Storm Following Lithium Removal via Hemodialysis: A Case Report.
[So] Source:Prim Care Companion CNS Disord;18(4), 2016 Jul 28.
[Is] ISSN:2155-7780
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Lítio/efeitos adversos
Diálise Renal/efeitos adversos
Crise Tireóidea/induzido quimicamente
Crise Tireóidea/diagnóstico
[Mh] Termos MeSH secundário: Adolescente
Feminino
Seres Humanos
[Pt] Tipo de publicação:CASE REPORTS; LETTER
[Nm] Nome de substância:
9FN79X2M3F (Lithium)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170308
[Lr] Data última revisão:
170308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161110
[St] Status:MEDLINE
[do] DOI:10.4088/PCC.15l01920


  10 / 770 MEDLINE  
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[PMID]:27804243
[Au] Autor:Chantra M; Limsuwan A; Mahachoklertwattana P
[Ad] Endereço:Division of Critical Care Medicine, Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand. marut.cha@mahidol.ac.th.
[Ti] Título:Low cardiac output thyroid storm in a girl with Graves' disease.
[So] Source:Pediatr Int;58(10):1080-1083, 2016 Oct.
[Is] ISSN:1442-200X
[Cp] País de publicação:Australia
[La] Idioma:eng
[Ab] Resumo:A 15-year-old girl with Graves' disease presented with hypotension after methimazole and propranolol were re-started for hyperthyroidism. She was found to have pulmonary artery hypertension resulting in obstructive shock. Thyroid storm was diagnosed according to Burch and Wartofsky score. She was promptly treated with anti-thyroid drugs, inorganic iodide, corticosteroid, and respiratory support. Pulmonary hypertension was treated with inhaled nitric oxide until the clinical status improved. Propranolol was withdrawn due to poor cardiac function. We herein present a unique case of a difficult-to-treat Graves' disease presenting with severe pulmonary hypertension resulting in low cardiac output thyroid storm.
[Mh] Termos MeSH primário: Baixo Débito Cardíaco/etiologia
Doença de Graves/complicações
Volume Sistólico/fisiologia
Crise Tireóidea/complicações
[Mh] Termos MeSH secundário: Adolescente
Baixo Débito Cardíaco/diagnóstico
Baixo Débito Cardíaco/fisiopatologia
Ecocardiografia
Feminino
Doença de Graves/diagnóstico
Seres Humanos
Radiografia Torácica
Crise Tireóidea/diagnóstico
[Pt] Tipo de publicação:CASE REPORTS
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170404
[Lr] Data última revisão:
170404
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161103
[St] Status:MEDLINE
[do] DOI:10.1111/ped.13102



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