Base de dados : MEDLINE
Pesquisa : C22.735 [Categoria DeCS]
Referências encontradas : 523 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 53 ir para página                         

  1 / 523 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28704366
[Au] Autor:Schneider-Crease I; Griffin RH; Gomery MA; Dorny P; Noh JC; Handali S; Chastain HM; Wilkins PP; Nunn CL; Snyder-Mackler N; Beehner JC; Bergman TJ
[Ad] Endereço:Department of Evolutionary Anthropology, Duke University, Durham, North Carolina, United States of America.
[Ti] Título:Identifying wildlife reservoirs of neglected taeniid tapeworms: Non-invasive diagnosis of endemic Taenia serialis infection in a wild primate population.
[So] Source:PLoS Negl Trop Dis;11(7):e0005709, 2017 Jul.
[Is] ISSN:1935-2735
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Despite the global distribution and public health consequences of Taenia tapeworms, the life cycles of taeniids infecting wildlife hosts remain largely undescribed. The larval stage of Taenia serialis commonly parasitizes rodents and lagomorphs, but has been reported in a wide range of hosts that includes geladas (Theropithecus gelada), primates endemic to Ethiopia. Geladas exhibit protuberant larval cysts indicative of advanced T. serialis infection that are associated with high mortality. However, non-protuberant larvae can develop in deep tissue or the abdominal cavity, leading to underestimates of prevalence based solely on observable cysts. We adapted a non-invasive monoclonal antibody-based enzyme-linked immunosorbent assay (ELISA) to detect circulating Taenia spp. antigen in dried gelada urine. Analysis revealed that this assay was highly accurate in detecting Taenia antigen, with 98.4% specificity, 98.5% sensitivity, and an area under the curve of 0.99. We used this assay to investigate the prevalence of T. serialis infection in a wild gelada population, finding that infection is substantially more widespread than the occurrence of visible T. serialis cysts (16.4% tested positive at least once, while only 6% of the same population exhibited cysts). We examined whether age or sex predicted T. serialis infection as indicated by external cysts and antigen presence. Contrary to the female-bias observed in many Taenia-host systems, we found no significant sex bias in either cyst presence or antigen presence. Age, on the other hand, predicted cyst presence (older individuals were more likely to show cysts) but not antigen presence. We interpret this finding to indicate that T. serialis may infect individuals early in life but only result in visible disease later in life. This is the first application of an antigen ELISA to the study of larval Taenia infection in wildlife, opening the doors to the identification and description of infection dynamics in reservoir populations.
[Mh] Termos MeSH primário: Doenças Endêmicas
Ensaio de Imunoadsorção Enzimática/métodos
Doenças dos Primatas/diagnóstico
Doenças dos Primatas/epidemiologia
Taenia/isolamento & purificação
Teníase/veterinária
Urina/parasitologia
[Mh] Termos MeSH secundário: Animais
Antígenos de Helmintos/urina
Etiópia/epidemiologia
Feminino
Masculino
Prevalência
Curva ROC
Sensibilidade e Especificidade
Teníase/diagnóstico
Teníase/epidemiologia
Theropithecus/parasitologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antigens, Helminth)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:171121
[Lr] Data última revisão:
171121
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170714
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pntd.0005709


  2 / 523 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28659484
[Au] Autor:Kapusinszky B; Ardeshir A; Mulvaney U; Deng X; Delwart E
[Ad] Endereço:Blood Systems Research Institute, San Francisco, California, USA.
[Ti] Título:Case-Control Comparison of Enteric Viromes in Captive Rhesus Macaques with Acute or Idiopathic Chronic Diarrhea.
[So] Source:J Virol;91(18), 2017 Sep 15.
[Is] ISSN:1098-5514
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Diarrhea is the major cause of non-research-associated morbidity and mortality affecting the supply of rhesus macaques and, potentially, their responses to experimental treatments. Idiopathic chronic diarrhea (ICD) in rhesus macaques also resembles ulcerative colitis, one form of human inflammatory bowel disease. To test for viral etiologies, we characterized and compared the fecal viromes from 32 healthy animals, 31 animals with acute diarrhea, and 29 animals with ICD. The overall fractions of eukaryotic viral reads were 0.063% for the healthy group, 0.131% for the acute-diarrhea group, and 0.297% for the chronic-diarrhea group. Eukaryotic viruses belonging to 6 viral families, as well as numerous circular Rep-encoding single-stranded DNA (CRESS DNA) viral genomes, were identified. The most commonly detected sequences were from picornaviruses, making up 59 to 88% of all viral reads, followed by 9 to 17% for CRESS DNA virus sequences. The remaining 5 virus families, , , , , and , collectively made up 1 to 3% of the viral reads, except for parvoviruses, which made up 23% of the viral reads in the healthy group. Detected members of the families and were highly diverse, consisting of multiple genera, species, and genotypes. Coinfections with members of up to six viral families were detected. Complete and partial viral genomes were assembled and used to measure the number of matching short sequence reads in feces from the 92 animals in the two clinical and the healthy control groups. Several enterovirus genotypes and CRESS DNA genomes were associated with ICD relative to healthy animals. Conversely, higher read numbers from different parvoviruses were associated with healthy animals. Our study reveals a high level of enteric coinfections with diverse viruses in a captive rhesus macaque colony and identifies several viruses positively or negatively associated with ICD.
[Mh] Termos MeSH primário: Diarreia/veterinária
Fezes/virologia
Macaca mulatta
Doenças dos Primatas/virologia
Viroses/veterinária
Vírus/classificação
Vírus/isolamento & purificação
[Mh] Termos MeSH secundário: Animais
Biodiversidade
Doença Crônica
Coinfecção/veterinária
Coinfecção/virologia
Diarreia/virologia
Viroses/virologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170907
[Lr] Data última revisão:
170907
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170630
[St] Status:MEDLINE


  3 / 523 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28231300
[Au] Autor:Levavasseur E; Biacabe AG; Comoy E; Culeux A; Grznarova K; Privat N; Simoneau S; Flan B; Sazdovitch V; Seilhean D; Baron T; Haïk S
[Ad] Endereço:Inserm U1127, CNRS UMR 7225, Sorbonne Universités, UPMC Univ Paris VI UMR S 1127, Institut du Cerveau et de la Moelle épinière, Paris, France.
[Ti] Título:Detection and partial discrimination of atypical and classical bovine spongiform encephalopathies in cattle and primates using real-time quaking-induced conversion assay.
[So] Source:PLoS One;12(2):e0172428, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The transmission of classical bovine spongiform encephalopathy (C-BSE) through contaminated meat product consumption is responsible for variant Creutzfeldt-Jakob disease (vCJD) in humans. More recent and atypical forms of BSE (L-BSE and H-BSE) have been identified in cattle since the C-BSE epidemic. Their low incidence and advanced age of onset are compatible with a sporadic origin, as are most cases of Creutzfeldt-Jakob disease (CJD) in humans. Transmissions studies in primates and transgenic mice expressing a human prion protein (PrP) indicated that atypical forms of BSE may be associated with a higher zoonotic potential than classical BSE, and require particular attention for public health. Recently, methods designed to amplify misfolded forms of PrP have emerged as promising tools to detect prion strains and to study their diversity. Here, we validated real-time quaking-induced conversion assay for the discrimination of atypical and classical BSE strains using a large series of bovine samples encompassing all the atypical BSE cases detected by the French Centre of Reference during 10 years of exhaustive active surveillance. We obtained a 100% sensitivity and specificity for atypical BSE detection. In addition, the assay was able to discriminate atypical and classical BSE in non-human primates, and also sporadic CJD and vCJD in humans. The RT-QuIC assay appears as a practical means for a reliable detection of atypical BSE strains in a homologous or heterologous PrP context.
[Mh] Termos MeSH primário: Síndrome de Creutzfeldt-Jakob/veterinária
Encefalopatia Espongiforme Bovina/diagnóstico
Encefalopatia Espongiforme Bovina/patologia
Doenças dos Primatas/diagnóstico
Proteínas Priônicas/análise
[Mh] Termos MeSH secundário: Animais
Encéfalo/patologia
Química Encefálica
Bovinos
Síndrome de Creutzfeldt-Jakob/diagnóstico
Síndrome de Creutzfeldt-Jakob/patologia
Seres Humanos
Proteínas Recombinantes/análise
Sensibilidade e Especificidade
[Pt] Tipo de publicação:JOURNAL ARTICLE; VALIDATION STUDIES
[Nm] Nome de substância:
0 (Prion Proteins); 0 (Recombinant Proteins)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170224
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0172428


  4 / 523 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28228395
[Au] Autor:Keasey SL; Pugh CL; Jensen SM; Smith JL; Hontz RD; Durbin AP; Dudley DM; O'Connor DH; Ulrich RG
[Ad] Endereço:Department of Biology, University of Maryland-Baltimore County, Baltimore, Maryland, USA.
[Ti] Título:Antibody Responses to Zika Virus Infections in Environments of Flavivirus Endemicity.
[So] Source:Clin Vaccine Immunol;24(4), 2017 Apr.
[Is] ISSN:1556-679X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Zika virus (ZIKV) infections occur in areas where dengue virus (DENV), West Nile virus (WNV), yellow fever virus (YFV), and other viruses of the genus cocirculate. The envelope (E) proteins of these closely related flaviviruses induce specific long-term immunity, yet subsequent infections are associated with cross-reactive antibody responses that may enhance disease susceptibility and severity. To gain a better understanding of ZIKV infections against a background of similar viral diseases, we examined serological immune responses to ZIKV, WNV, DENV, and YFV infections of humans and nonhuman primates (NHPs). Using printed microarrays, we detected very specific antibody responses to primary infections with probes of recombinant E proteins from 15 species and lineages of flaviviruses pathogenic to humans, while high cross-reactivity between ZIKV and DENV was observed with 11 printed native viruses. Notably, antibodies from human primary ZIKV or secondary DENV infections that occurred in areas where flavivirus is endemic broadly recognized E proteins from many flaviviruses, especially DENV, indicating a strong influence of infection history on immune responses. A predictive algorithm was used to tentatively identify previous encounters with specific flaviviruses based on serum antibody interactions with the multispecies panel of E proteins. These results illustrate the potential impact of exposure to related viruses on the outcome of ZIKV infection and offer considerations for development of vaccines and diagnostics.
[Mh] Termos MeSH primário: Anticorpos Antivirais/sangue
Formação de Anticorpos
Reações Cruzadas
Doenças Endêmicas
Infecções por Flaviviridae/imunologia
Infecções por Flaviviridae/veterinária
[Mh] Termos MeSH secundário: Animais
Seres Humanos
Macaca mulatta
Análise em Microsséries
Doenças dos Primatas/imunologia
Análise Serial de Proteínas
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antibodies, Viral)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:171006
[Lr] Data última revisão:
171006
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170224
[St] Status:MEDLINE


  5 / 523 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
[PMID]:28222842
[Au] Autor:Kim J; Coble DJ; Salyards GW; Bower JK; Rinaldi WJ; Plauche GB; Habing GG
[Ad] Endereço:Department of Veterinary Preventive Medicine, College of Veterinary Medicine, College of Public Health, The Ohio State University, Columbus, Ohio.
[Ti] Título:Antimicrobial Use for and Resistance of Zoonotic Bacteria Recovered from Nonhuman Primates.
[So] Source:Comp Med;67(1):79-86, 2017 Feb 01.
[Is] ISSN:1532-0820
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:As a growing threat to human and animal health, antimicrobial resistance (AMR) has become a central public-health topic. Largescale surveillance systems, such as the National Antimicrobial Resistance Monitoring System (NARMS), are now established to monitor and provide guidance regarding AMR, but comprehensive literature on AMR among NHP is sparse. This study provides data regarding current antimicrobial use strategies and the prevalence of AMR in zoonotic bacteria recovered from NHP within biomedical research institutions. We focused on 4 enteric bacteria: Shigella flexneri, Yersinia enterocolitica, Y. pseudotuberculosis, and Campylobacter jejuni. Fifteen veterinarians, 7 biomedical research institutions, and 4 diagnostic laboratories participated, providing susceptibility test results from January 2012 through April 2015. Veterinarians primarily treated cases caused by S. flexneri, Y. enterocolitica, and Y. pseudotuberculosis with enrofloxacin but treated C. jejuni cases with azithromycin and tylosin. All isolates were susceptible to the associated primary antimicrobial but often showed resistance to others. Specifically, S. flexneri isolates frequently were resistant to erythromycin (87.5%), doxycycline (73.7%), and tetracycline (38.3%); Y. enterocolitica isolates to ampicillin (100%) and cefazolin (93.6%); and C. jejuni isolates to methicillin (99.5%) and cephalothin (97.5%). None of the 58 Y. pseudotuber-culosis isolates was resistant to any tested antimicrobial. Notably, resistance patterns were not shared between this study's NHP isolates and human isolates presented by NARMS. Our findings indicate that zoonotic bacteria from NHP diagnostic samples are broadly susceptible to the antimicrobials used to treat the clinical infections. These results can help veterinarians ensure effective antimicrobial therapy and protect staff by minimizing occupational risk.
[Mh] Termos MeSH primário: Antibacterianos/uso terapêutico
Infecções por Campylobacter/veterinária
Campylobacter jejuni/efeitos dos fármacos
Resistência Microbiana a Medicamentos
Infecções por Enterobacteriaceae/veterinária
Shigella flexneri/efeitos dos fármacos
Yersinia enterocolitica/efeitos dos fármacos
Yersinia pseudotuberculosis/efeitos dos fármacos
[Mh] Termos MeSH secundário: Animais
Infecções por Campylobacter/tratamento farmacológico
Infecções por Campylobacter/epidemiologia
Campylobacter jejuni/isolamento & purificação
Estudos Transversais
Infecções por Enterobacteriaceae/tratamento farmacológico
Infecções por Enterobacteriaceae/epidemiologia
Testes de Sensibilidade Microbiana/estatística & dados numéricos
Testes de Sensibilidade Microbiana/veterinária
Prevalência
Doenças dos Primatas
Primatas
Estudos Retrospectivos
Shigella flexneri/isolamento & purificação
Inquéritos e Questionários
Yersinia enterocolitica/isolamento & purificação
Yersinia pseudotuberculosis/isolamento & purificação
Zoonoses/tratamento farmacológico
Zoonoses/microbiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Bacterial Agents)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170821
[Lr] Data última revisão:
170821
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170223
[St] Status:MEDLINE


  6 / 523 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Pissinatti, Alcides
Texto completo
[PMID]:28187764
[Au] Autor:Alvarenga DA; Pina-Costa A; Bianco C; Moreira SB; Brasil P; Pissinatti A; Daniel-Ribeiro CT; Brito CF
[Ad] Endereço:Laboratório de Malária, Centro de Pesquisa René Rachou (CPqRR), Fundação Oswaldo Cruz (Fiocruz), Belo Horizonte, MG, Brazil.
[Ti] Título:New potential Plasmodium brasilianum hosts: tamarin and marmoset monkeys (family Callitrichidae).
[So] Source:Malar J;16(1):71, 2017 Feb 10.
[Is] ISSN:1475-2875
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Non-human primates (NHPs) as a source for Plasmodium infections in humans are a challenge for malaria elimination. In Brazil, two species of Plasmodium have been described infecting NHPs, Plasmodium brasilianum and Plasmodium simium. Both species are infective to man. Plasmodium brasilianum resembles morphologically, genetically and immunologically the human quartan Plasmodium malariae. Plasmodium brasilianum naturally infects species of non-human primates from all New World monkey families from a large geographic area. In the family Callitrichidae only the genus Saguinus has been described infected so far. The present study describes the natural infection of P. brasilianum in tamarins and marmosets of the genera Callithrix, Mico and Leontopithecus in the Atlantic forest. METHODS: One hundred and twenty-two NHPs of the family Callitrichidae housed in the Primate Centre of Rio de Janeiro (CPRJ) were sampled in June 2015, and January and July 2016. The CPRJ is located in the Atlantic forest in the Guapimirim municipality, in the Rio de Janeiro state, where human autochthonous cases of malaria have been reported. The samples were screened for the presence of Plasmodium using optical microscopy and nested PCR for detection of 18S small subunit rRNA gene. The amplicon was sequenced to confirm the molecular diagnosis. RESULTS: The frequency of Plasmodium infections detected by nested PCR in New World monkeys of the family Callitrichidae was 6.6%. For the first time, Callitrichidae primates of genera Callithrix, Mico and Leontopithecus were found naturally infected with P. brasilianum. Infection was confirmed by sequencing a small fragment of 18S rRNA gene, although no parasites were detected in blood smears. CONCLUSIONS: The reported P. brasilianum infection in NHP species maintained in captivity suggests that infection can be favoured by the presence of vectors and the proximity between known (and unknown) hosts of malaria. Thus, the list of potential malaria reservoirs needs to be further explored.
[Mh] Termos MeSH primário: Callitrichinae/parasitologia
Malária/veterinária
Plasmodium/classificação
Plasmodium/isolamento & purificação
Doenças dos Primatas/parasitologia
[Mh] Termos MeSH secundário: Animais
Brasil
DNA de Protozoário/química
DNA de Protozoário/genética
DNA Ribossômico/química
DNA Ribossômico/genética
Malária/parasitologia
Microscopia
Plasmodium/citologia
Plasmodium/genética
Reação em Cadeia da Polimerase
RNA de Protozoário/genética
RNA Ribossômico 18S/genética
Análise de Sequência de DNA
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Protozoan); 0 (DNA, Ribosomal); 0 (RNA, Protozoan); 0 (RNA, Ribosomal, 18S)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170608
[Lr] Data última revisão:
170608
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170212
[St] Status:MEDLINE
[do] DOI:10.1186/s12936-017-1724-0


  7 / 523 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28039076
[Au] Autor:Navarro R; Aung MS; Cruz K; Ketzis J; Gallagher CA; Beierschmitt A; Malik YS; Kobayashi N; Ghosh S
[Ad] Endereço:Department of Biomedical Sciences, Ross University School of Veterinary Medicine, Saint Kitts and Nevis, West Indies.
[Ti] Título:Whole genome analysis provides evidence for porcine-to-simian interspecies transmission of rotavirus-A.
[So] Source:Infect Genet Evol;49:21-31, 2017 Apr.
[Is] ISSN:1567-7257
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:We report here whole genome analysis of a porcine rotavirus-A (RVA) strain RVA/Pig-wt/KNA/ET8B/2015/G5P[13] detected in a diarrheic piglet, and nearly whole genome (except for VP4 gene) analysis of a simian RVA strain RVA/Simian-wt/KNA/08979/2015/G5P[X] detected in a non-diarrheic African green monkey (AGM) on the island of St. Kitts, Caribbean region. Strain ET8B exhibited a G5-P[13]-I5-R1-C1-M1-A8-N1-T7-E1-H1 genotype constellation that was identical to those of Brazilian porcine RVA G5P[13] strains RVA/Pig-wt/BRA/ROTA01/2013/G5P[13] and RVA/Pig-wt/BRA/ROTA07/2013/G5P[13], the only porcine G5P[13] RVAs that have been analyzed for the whole genome so far. Phylogenetically, all the 11 gene segments of ET8B were closely related to those of porcine and porcine-like human RVAs within the respective genotypes. Although the porcine G5P[13] RVAs exhibited identical genotype constellations, ET8B did not appear to share common evolutionary pathways with the Brazilian porcine G5P[13] RVAs. Interestingly, the VP2, VP3, VP6, VP7, and NSP1-NSP5 genes of simian RVA strain 08979 were closely related to those of porcine and porcine-like human RVA strains, exhibiting 99%-100% nucleotide sequence identities to cognate genes of co-circulating porcine RVA strain ET8B. On the other hand, the VP1 of 08979 appeared to be genetically divergent from porcine and human RVAs within the R1 genotype, and its exact origin could not be ascertained. Taken together, these observations suggested that simian strain 08979 might have been derived from interspecies transmission events involving transmission of ET8B-like RVAs from pigs to AGMs. In St. Kitts, AGMs often stray from the wild into livestock farms. Therefore, it may be possible that the AGM acquired the infection from a pig farm on the island. To our knowledge, this is the first report on detection of porcine-like RVAs in monkeys. Also, the present study is the first to report whole genomic analysis of a porcine RVA strain from the Caribbean region.
[Mh] Termos MeSH primário: Genoma Viral
Filogenia
Doenças dos Primatas/epidemiologia
RNA Viral/genética
Infecções por Rotavirus/veterinária
Rotavirus/genética
Doenças dos Suínos/epidemiologia
[Mh] Termos MeSH secundário: Animais
Sequência de Bases
Cercopithecus aethiops
Genótipo
Doenças dos Primatas/transmissão
Doenças dos Primatas/virologia
Rotavirus/classificação
Rotavirus/isolamento & purificação
Infecções por Rotavirus/epidemiologia
Infecções por Rotavirus/transmissão
Infecções por Rotavirus/virologia
Alinhamento de Sequência
Suínos
Doenças dos Suínos/transmissão
Doenças dos Suínos/virologia
Índias Ocidentais/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (RNA, Viral)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171010
[Lr] Data última revisão:
171010
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170101
[St] Status:MEDLINE


  8 / 523 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27641729
[Au] Autor:Reuter G; Pankovics P; Boros Á
[Ad] Endereço:Regional Laboratory of Virology, National Reference Laboratory of Gastroenteric Viruses, ÁNTSZ Regional Institute of State Public Health Service, Pécs, Hungary.
[Ti] Título:Saliviruses-the first knowledge about a newly discovered human picornavirus.
[So] Source:Rev Med Virol;27(1), 2017 Jan.
[Is] ISSN:1099-1654
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The salivirus, first discovered in the year 2009, is a member of the large and growing family Picornaviridae. At present, the genus Salivirus contains 1 species Salivirus A and 2 genotypes, Salivirus A1 and Salivirus A2. Salivirus has been identified in humans and chimpanzees and may cause acute gastroenteritis in humans, having been detected in 0% to 8.7% of fecal samples collected from gastroenteritis in different human populations. Salivirus is ubiquitous in wastewater of human origin and river water specimens worldwide and represents a potential indicator human RNA virus for monitoring of environmental samples. This review summarizes the current knowledge on saliviruses including discovery, taxonomy, genome structure, and genetic diversity; covers all aspects of infection including epidemiology, molecular epidemiology, clinical feature, host species, environmental characteristics, and laboratory diagnosis; and gives a summary of possible future perspectives.
[Mh] Termos MeSH primário: Variação Genética
Infecções por Picornaviridae/veterinária
Infecções por Picornaviridae/virologia
Picornaviridae/classificação
Picornaviridae/genética
[Mh] Termos MeSH secundário: Animais
Fezes/virologia
Gastroenterite/virologia
Genótipo
Seres Humanos
Pan troglodytes
Picornaviridae/isolamento & purificação
Infecções por Picornaviridae/epidemiologia
Infecções por Picornaviridae/patologia
Doenças dos Primatas/virologia
Rios/virologia
Águas Residuais/virologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Waste Water)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170822
[Lr] Data última revisão:
170822
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160920
[St] Status:MEDLINE
[do] DOI:10.1002/rmv.1904


  9 / 523 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:25683191
[Au] Autor:Koga T; Aoki W; Mizuno T; Wakazono K; Ohno J; Nakai T; Nomiya T; Fujii M; Fusegawa K; Kinoshita K; Hamada T; Ikeda Y
[Ad] Endereço:Biological Research Laboratories, Daiichi Sankyo Co., Ltd., Tokyo, Japan. Electronic address: koga.tetsufumi.zj@daiichisankyo.co.jp.
[Ti] Título:Antimicrobial resistance in Campylobacter coli and Campylobacter jejuni in cynomolgus monkeys (Macaca fascicularis) and eradication regimens.
[So] Source:J Microbiol Immunol Infect;50(1):75-82, 2017 Feb.
[Is] ISSN:1995-9133
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Campylobacter spp. are zoonotic pathogens, however, knowledge about their presence and antimicrobial resistance in nonhuman primates is limited. Our animal facility purchased cynomolgus monkeys (Macaca fascicularis) from various Asian countries: China, Cambodia, Indonesia, the Philippines, and Vietnam. METHODS: Colonization by Campylobacter spp. was investigated in 238 of the monkeys from 2009 to 2012 and antimicrobial susceptibility testing was carried out for these isolates. Furthermore, we eradicated these pathogens from these monkeys. RESULTS: Campylobacter spp. were isolated from 47 monkeys from three specific countries: China, Cambodia, and Indonesia, with respective isolation rates of 15%, 36%, and 67%. Two monkeys, which were each infected with Campylobacter jejuni and Campylobacter coli, showed clinical symptoms of diarrhea and bloody feces. In total, 41 isolates of C. coli and 17 isolates of C. jejuni were detected. Antimicrobial susceptibility varied: in the monkeys from China, erythromycin (ERY)-, tetracycline (TET)-, and ciprofloxacin-resistant C. coli, in the monkeys from Cambodia, amoxicillin-intermediate, TET- and ciprofloxacin-resistant C. coli and amoxicillin- and ciprofloxacin-resistant C. jejuni, and in the monkeys from Indonesia, ciprofloxacin-resistant C. coli and TET- and ciprofloxacin-resistant C. jejuni were common (>75%). Multiresistant isolates of C. coli were found in monkeys from all countries and multiresistant isolates of C. jejuni were found in monkeys from Indonesia. The eradication rate with azithromycin was comparable to that with gentamicin (GEN) by oral administration, and was higher than those with amoxicillin-clavulanic acid (AMC) and chloramphenicol (CHL). CONCLUSION: From the perspective of zoonosis, we should acknowledge multiresistant Campylobacter spp. isolated from the monkeys as a serious warning.
[Mh] Termos MeSH primário: Antibacterianos/uso terapêutico
Infecções por Campylobacter/veterinária
Campylobacter coli/efeitos dos fármacos
Campylobacter jejuni/efeitos dos fármacos
Doenças dos Primatas/microbiologia
[Mh] Termos MeSH secundário: Animais
Antibacterianos/farmacologia
Infecções por Campylobacter/tratamento farmacológico
Infecções por Campylobacter/microbiologia
Campylobacter coli/isolamento & purificação
Campylobacter jejuni/isolamento & purificação
Farmacorresistência Bacteriana
Feminino
Macaca fascicularis
Masculino
Testes de Sensibilidade Microbiana
Doenças dos Primatas/tratamento farmacológico
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Bacterial Agents)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170322
[Lr] Data última revisão:
170322
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150217
[St] Status:MEDLINE


  10 / 523 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27940463
[Au] Autor:Skoog EC; Deck SL; Entwistle HD; Hansen LM; Solnick JV
[Ad] Endereço:Departments of Medicine and of Microbiology & Immunology, Center for Comparative Medicine, California National Primate Research Center, University of California Davis, Davis, CA 95616, USA.
[Ti] Título:Characterization of the Cag pathogenicity island in Helicobacter pylori from naturally infected rhesus macaques.
[So] Source:FEMS Microbiol Lett;363(24), 2016 Dec.
[Is] ISSN:1574-6968
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Helicobacter pylori commonly infects the epithelial layer of the human stomach and in some individuals causes peptic ulcers, gastric adenocarcinoma or gastric lymphoma. Helicobacter pylori is a genetically diverse species, and the most important bacterial virulence factor that increases the risk of developing disease, versus asymptomatic colonization, is the cytotoxin associated gene pathogenicity island (cagPAI). Socially housed rhesus macaques are often naturally infected with H. pylori similar to that which colonizes humans, but little is known about the cagPAI. Here we show that H. pylori strains isolated from naturally infected rhesus macaques have a cagPAI very similar to that found in human clinical isolates, and like human isolates, it encodes a functional type IV secretion system. These results provide further support for the relevance of rhesus macaques as a valid experimental model for H. pylori infection in humans.
[Mh] Termos MeSH primário: Ilhas Genômicas
Infecções por Helicobacter/veterinária
Helicobacter pylori/genética
Macaca mulatta
Doenças dos Primatas/microbiologia
[Mh] Termos MeSH secundário: Animais
Genes Bacterianos
Infecções por Helicobacter/microbiologia
Helicobacter pylori/isolamento & purificação
Homologia de Sequência
Sistemas de Secreção Tipo IV/genética
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Type IV Secretion Systems)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170829
[Lr] Data última revisão:
170829
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161213
[St] Status:MEDLINE



página 1 de 53 ir para página                         
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde