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[PMID]:29205970
[Au] Autor:Xu WJ; Ji P
[Ad] Endereço:Criminal Police Brigade of Liyang Public Security Bureau, Liyang 213300, China.
[Ti] Título:[Retrospective Analysis of 17 Family Homicide Cases].
[So] Source:Fa Yi Xue Za Zhi;32(6):431-433, 2016 Dec.
[Is] ISSN:1004-5619
[Cp] País de publicação:China
[La] Idioma:chi
[Ab] Resumo:OBJECTIVES: To summarize the characteristics of family homicide cases and to provide reference for the analysis and prevention of such cases. METHODS: Seventeen solved family homicide cases in Liyang from 2004 to 2014 were investigated. The original registration information, record of scene investigation, corpse inspection report and case situation were analyzed statistically. RESULTS: The characteristics of the 17 family homicides cases showed that most victims were female and most suspects were male, and spouse infidelity and suspected spouse infidelity have higher proportion in the motives for the killings. Murders by patients with psychosis, camouflage murders and murder-suicides occupied a certain proportion in the family homicide cases. CONCLUSIONS: The family homicide cases are correlated with the family factors such as extramarital sexual intercourse and murder by patients with psychosis. Some suspects suicided after murder. The tools for committing crimes have the features of simplicity, randomness and easy source availability.
[Mh] Termos MeSH primário: Homicídio
Motivação
[Mh] Termos MeSH secundário: Cadáver
Vítimas de Crime
Família
Feminino
Seres Humanos
Masculino
Transtornos Psicóticos
Estudos Retrospectivos
Suicídio
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171206
[St] Status:MEDLINE
[do] DOI:10.3969/j.issn.1004-5619.2016.06.009


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[PMID]:29188664
[Au] Autor:Lou XP; Zhang W; Zheng J; Xu H; Zhao F
[Ad] Endereço:Department of Forensic Medicine, Medical College of Nanchang University, Nanchang 330006, China.
[Ti] Título:[Comparative Study on Morphology of Human, Swine, Sheep and Cattle Muscle Tissues and Its Forensic Significance].
[So] Source:Fa Yi Xue Za Zhi;32(4):250-253, 2016 Aug.
[Is] ISSN:1004-5619
[Cp] País de publicação:China
[La] Idioma:chi
[Ab] Resumo:OBJECTIVES: To observe the morphological characteristic indexes of the muscle tissues from different species and to establish a discriminant equation of species identification and tried to establish a new method for species identification. METHODS: Three different parts of the muscle tissues, triceps brachii, biceps femoris and erector spinae from adult human corpses, triceps brachii, biceps femoris and longissimus dorsi muscle from swine, sheep and cattle reached the slaughter age, were extracted respectively (20 for each group) and deal the tissues into paraffin sections. Eleven observational indexes of the muscle tissues from adult human corpses, swine, sheep and cattle were detected. Statistical methods were used to analyze the data and a discriminant equation of species identification was established. RESULTS: Four observation indicators were screened for establishing the discriminant equation of species identification among human, swine, sheep and cattle. The accurate rate of this method for human muscle tissue identification was 90%, and for swine, sheep, and cattle muscle tissue were 80%, 100% and 80% respectively. CONCLUSIONS: The morphological method provides a new method for the species identification of the muscle tissue among human, swine, sheep and cattle, and it can be used as a reference for the identification of animal species.
[Mh] Termos MeSH primário: Músculo Esquelético/anatomia & histologia
[Mh] Termos MeSH secundário: Animais
Cadáver
Bovinos
Antropologia Forense
Seres Humanos
Ovinos
Suínos
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171201
[St] Status:MEDLINE
[do] DOI:10.3969/j.issn.1004-5619.2016.04.003


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[PMID]:28457516
[Au] Autor:Nakata M; Kasuda S; Yuui K; Kudo R; Hatake K
[Ad] Endereço:Department of Legal Medicine, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634-8521, Japan. Electronic address: dc112064@naramed-u.ac.jp.
[Ti] Título:Relevance of hemolysis-induced tissue factor expression on monocytes in soft clot formation in alcohol-containing blood.
[So] Source:Leg Med (Tokyo);25:83-88, 2017 Mar.
[Is] ISSN:1873-4162
[Cp] País de publicação:Ireland
[La] Idioma:eng
[Ab] Resumo:The fluidity of cadaveric blood is an important characteristic in the post-mortem examination of cases of asphyxial death. Although it is empirically known that soft blood clots are present in cadaveric blood containing alcohol, the relationship between such clots and blood alcohol is unclear. We addressed this issue through in vitro studies using blood collected from healthy volunteers. Assessment of global hemostasis by rotational thromboelastometry revealed that ethanol treatment enhanced the procoagulant activity of whole blood. However, ethanol inhibited epinephrine-induced platelet aggregation, whereas plasma levels of von Willebrand factor and the activity of coagulation factors VIII and IX were unaffected. In contrast, tissue factor (TF) activity was higher in plasma obtained from ethanol-treated whole blood than that in plasma from untreated blood. Ethanol induced hemolysis of red blood cells, and the consequent hemoglobin (Hb) release promoted de novo synthesis of TF in isolated monocytes, as determined by real-time reverse transcription PCR, western blotting, and flow cytometry. However, ethanol itself did not induce TF expression in monocytes. Given that TF activates the extrinsic coagulation pathway and amplifies hemostatic reactions, Hb-induced TF expression in monocytes might contribute to soft blood clot formation.
[Mh] Termos MeSH primário: Coagulação Sanguínea/efeitos dos fármacos
Etanol/sangue
Hemólise
Monócitos/efeitos dos fármacos
Tromboplastina/efeitos dos fármacos
[Mh] Termos MeSH secundário: Autopsia
Cadáver
Citometria de Fluxo
Medicina Legal
Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
3K9958V90M (Ethanol); 9035-58-9 (Thromboplastin)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180307
[Lr] Data última revisão:
180307
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170502
[St] Status:MEDLINE


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[PMID]:28457512
[Au] Autor:Soltani S; Aghakhani K; Fallah F
[Ad] Endereço:Department of Forensic Medicine and Toxicology, Iran University of Medical Sciences, Tehran, Iran.
[Ti] Título:Sex prediction potential of hyoid metric measurements in Iranian adults.
[So] Source:Leg Med (Tokyo);25:6-10, 2017 Mar.
[Is] ISSN:1873-4162
[Cp] País de publicação:Ireland
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: Human hyoid is sexually dimorphic and is useful for sexing unknown skeletal remains. We aimed to find sex prediction potential of three linear dimensions of hyoid bones obtained from a series of cadavers with Persian ethnicity. METHODS: This cross-sectional study was carried out in 2015 at Forensic Pathology Organization of Tehran, Iran. We directly measured three linear dimensions of a series of hyoid samples obtained from cadavers during their neck autopsy in a convenience method. These dimensions were width, length and distance between lesser horns of hyoid. Height and weight of cadavers were also documented. Cadavers were of Persian ethnicity and at least 25-year-old. Data were analyzed by SPSS16. Logistic Regression Model was applied to find independent sex predictor(s) of hyoid. Statistically significant level was considered <0.05. RESULTS: Hyoids of 349 adult cadavers (176 females and 173 males) with mean±SD age of 39.91±8.13years were investigated. Male cadavers had significantly higher BMI values (p-value<0.001). Mean±SD for width, length and distance between lesser horns of hyoids were 34.45±4.70, 34.61±4.67 and 22.71±2.80mm, respectively. All measured dimensions had greater mean values in males (all with p-values<0.001). After adjusting for BMI, length and distance between lesser horns of hyoid were independent predictors of sex with odd's ratio of 4.67 and 1.97, respectively. Combining these two measurements provided sex classification accuracy of 97.4%. CONCLUSION: Special metric hyoid indicators can help in accurate sexing of skeletal remnants of adult Iranians. Further studies will find the strongest sex predictors of hyoid bones among Persians.
[Mh] Termos MeSH primário: Osso Hioide/anatomia & histologia
Determinação do Sexo pelo Esqueleto/métodos
[Mh] Termos MeSH secundário: Adulto
Índice de Massa Corporal
Cadáver
Estudos Transversais
Feminino
Seres Humanos
Irã (Geográfico)
Masculino
Meia-Idade
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180307
[Lr] Data última revisão:
180307
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170502
[St] Status:MEDLINE


  5 / 35505 MEDLINE  
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[PMID]:28457504
[Au] Autor:Okumura M; Usumoto Y; Tsuji A; Kudo K; Ikeda N
[Ad] Endereço:Department of Forensic Pathology and Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan.
[Ti] Título:Analysis of postmortem changes in internal organs and gases using computed tomography data.
[So] Source:Leg Med (Tokyo);25:11-15, 2017 Mar.
[Is] ISSN:1873-4162
[Cp] País de publicação:Ireland
[La] Idioma:eng
[Ab] Resumo:Postmortem computed tomography (PMCT) is a useful method to identify various causes of death and measure the volume of internal organs and gases. The purpose of this study was to investigate postmortem changes as measured by PMCT, and the relationship between the volume of organs and gases and postmortem interval (PMI). Forty-six cadavers (22 men, 24 women) were examined by CT before autopsy. The volumes of the lungs, intrahepatic gas, and intrarectal gas were measured by CT using a workstation. A stepwise regression analysis was used to establish a predictive equation to ascertain the measured volume using factors including sex, age, height, body mass index (BMI), body surface area (BSA), and PMI. For estimation of PMI, stepwise regression analysis was used. In the equations for each measured volume, height, diaphragmatic height, and BSA were adopted for the left lung; height and diaphragmatic height were adopted for the right lung; PMI was adopted for intrahepatic gas; and sex and PMI were adopted for intrarectal gas. In the PMI equations, left lung volume, intrahepatic gas, and intrarectal gas were adopted together with sex, weight, and BMI. Values of intrahepatic gas decreased with postmortem changes, while intrarectal gas increased. This may be useful in investigation of postmortem changes. It will be necessary to include other parts of the intestine and to analyze volume changes in gases from these parts after death.
[Mh] Termos MeSH primário: Patologia Legal/métodos
Tomografia Computadorizada Multidetectores
Mudanças Depois da Morte
[Mh] Termos MeSH secundário: Cadáver
Feminino
Gases/análise
Seres Humanos
Masculino
Tecnologia Radiológica
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Gases)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180307
[Lr] Data última revisão:
180307
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170502
[St] Status:MEDLINE


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[PMID]:28749741
[Au] Autor:Edgar CM; Singh H; Obopilwe E; Voss A; Divenere J; Tassavor M; Comer B; Sanchez G; Mazzocca AD; Provencher MT
[Ad] Endereço:Department of Orthopaedic Surgery, New England Musculoskeletal Institute, University of Connecticut School of Medicine, Farmington, Connecticut, USA.
[Ti] Título:Pectoralis Major Repair: A Biomechanical Analysis of Modern Repair Configurations Versus Traditional Repair Configuration.
[So] Source:Am J Sports Med;45(12):2858-2863, 2017 Oct.
[Is] ISSN:1552-3365
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Pectoralis major (PM) ruptures are increasingly common, and a variety of surgical techniques have been described. However, tested techniques have demonstrated diminished strength with inadequate restoration of the footprint and suture failure at relatively low loads. Purpose/Hypothesis: The purpose was to biomechanically compare PM transosseous suture repair (current gold standard) to modern PM repair techniques that use larger caliber sutures, suture tape, and unicortical button fixation (UBF). The null hypothesis was that there would be no mechanical difference between repair techniques and no difference in the amount of footprint restoration. STUDY DESIGN: Controlled laboratory study. METHODS: Twenty-four fresh-frozen cadaveric shoulders controlled for age and bone mineral density were randomized equally to 4 groups: (1) UBF, suture tape; (2) UBF, No. 5 suture, suture tape; (3) bone trough with No. 2 suture; and (4) native PM tendon group; all groups were tested to failure. The specimens were tested under cycling loads (10 N to 125 N) with a final load-to-failure test at 1 mm/s. Failure modes were classified by location and cause of rupture based on optical markers, while tendon footprint length was measured to determine amount of footprint restoration. RESULTS: For fixation strength, the mean peak load was significantly greater in the native tendon (1816 ± 706 N) versus UBF/No. 5 suture/suture tape (794 ± 168 N), UBF/suture tape (502 ± 201 N), and bone trough (492 ± 151 N) ( P < .001 for all). UBF/No. 5 suture/suture tape featured the lowest displacement superiorly (1.09 ± 0.47 mm) and inferiorly (1.14 ± 0.39 mm) with a significant difference compared with bone trough. With regard to tendon footprint reapproximation, cortical button fixation best approximated native tendon footprint length versus bone trough. CONCLUSION: Based on peak failure load, the UBF/No. 5 suture/suture tape construct demonstrated 61% greater construct strength than a traditional bone trough technique. Moreover, displacement after cyclic loading was by far smallest in the UBF/No. 5 suture/suture tape construct. Therefore, repair constructs with larger caliber suture and suture tape provide a measurable improvement in construct strength versus traditional PM repair techniques in a biomechanical model and may be advantageous for repair. CLINICAL RELEVANCE: Cortical button fixation with larger caliber suture and suture tape allows for a significantly better PM repair than more traditional techniques at the time of surgery, which may ultimately result in improved clinical outcomes if implemented in surgical practice.
[Mh] Termos MeSH primário: Procedimentos Ortopédicos/métodos
Músculos Peitorais/fisiologia
Músculos Peitorais/cirurgia
Ruptura/cirurgia
[Mh] Termos MeSH secundário: Idoso
Fenômenos Biomecânicos
Cadáver
Feminino
Seres Humanos
Masculino
Meia-Idade
Músculos Peitorais/lesões
Ruptura/fisiopatologia
Âncoras de Sutura
Técnicas de Sutura
Resistência à Tração
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180306
[Lr] Data última revisão:
180306
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170728
[St] Status:MEDLINE
[do] DOI:10.1177/0363546517716175


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[PMID]:29301514
[Au] Autor:McCafferty S; Levine J; Schwiegerling J; Enikov ET
[Ad] Endereço:Department of Ophthalmology, Intuor Technologies, University of Arizona- College of Medicine, University of Arizona- College of Optical Science, LLC 6422 E. Speedway Blvd. Suite 100, Tucson, AZ, 85710, USA. sjmccafferty66@hotmail.com.
[Ti] Título:Goldmann and error correcting tonometry prisms compared to intracameral pressure.
[So] Source:BMC Ophthalmol;18(1):2, 2018 Jan 04.
[Is] ISSN:1471-2415
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Compare Goldmann applanation tonometer (GAT) prism and correcting applanation tonometry surface (CATS) prism to intracameral intraocular pressure (IOP), in vivo and in vitro. METHODS: Pressure transducer intracameral IOP was measured on fifty-eight (58) eyes undergoing cataract surgery and the IOP was modulated manometrically to 10, 20, and 40 mmHg. Simultaneously, IOP was measured using a Perkins tonometer with a standard GAT prism and a CATS prism at each of the intracameral pressures. Statistical comparison was made between true intracameral pressures and the two prism measurements. Differences between the two prism measurements were correlated to central corneal thickness (CCT) and corneal resistance factor (CRF). Human cadaver eyes were used to assess measurement repeatability. RESULTS: The CATS tonometer prism measured closer to true intracameral IOP than the GAT prism by 1.7+/-2.7 mmHg across all pressures and corneal properties. The difference in CATS and GAT measurements was greater in thin CCT corneas (2.7+/-1.9 mmHg) and low resistance (CRF) corneas (2.8+/-2.1 mmHg). The difference in prisms was negligible at high CCT and CRF values. No difference was seen in measurement repeatability between the two prisms. CONCLUSION: A CATS prism in Goldmann tonometer armatures significantly improve the accuracy of IOP measurement compared to true intracameral pressure across a physiologic range of IOP values. The CATS prism is significantly more accurate compared to the GAT prism in thin and less rigid corneas. The in vivo intracameral study validates mathematical models and clinical findings in IOP measurement between the GAT and CATS prisms.
[Mh] Termos MeSH primário: Erros de Diagnóstico
Pressão Intraocular/fisiologia
Modelos Teóricos
Hipertensão Ocular/diagnóstico
Tonometria Ocular/instrumentação
[Mh] Termos MeSH secundário: Idoso
Cadáver
Desenho de Equipamento
Feminino
Seres Humanos
Masculino
Hipertensão Ocular/fisiopatologia
Estudos Prospectivos
Reprodutibilidade dos Testes
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180305
[Lr] Data última revisão:
180305
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180106
[St] Status:MEDLINE
[do] DOI:10.1186/s12886-017-0668-z


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[PMID]:29364934
[Au] Autor:Christen P; Boutroy S; Ellouz R; Chapurlat R; van Rietbergen B
[Ad] Endereço:Institute for Biomechanics, ETH Zurich, Zurich, Switzerland.
[Ti] Título:Least-detectable and age-related local in vivo bone remodelling assessed by time-lapse HR-pQCT.
[So] Source:PLoS One;13(1):e0191369, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:We previously developed an image analysis approach for the determination of local sites of bone remodelling using time-lapse in vivo HR-pQCT. The involved image filtering for removing noise was chosen rather aggressively, and also removed some effects of the bone remodelling. In this paper, we quantify these filtering settings using ex vivo reproducibility HR-pQCT images, and determine the least-detectable bone remodelling using in vivo reproducibility HR-pQCT images, as well as testing whether the approach is capable of capturing age-related bone remodelling by use of in vivo long-term HR-pQCT images. We found that a threshold value of 225 mg HA/cm3 for the filtering led to acceptable results with falsely determined bone remodelling of less than 0.5%, and that the least-detectable bone formation and bone resorption are 2.0 ± 1.0% and 2.2 ± 0.7% respectively. We also found that age-related local bone remodelling can be captured satisfactorily in postmenopausal women. The latter revealed new insights into the effect of ageing on bone remodelling, and showed that bone remodelling seems to take place through a few small formation packets and many large resorption volumes leading to a net bone loss. We conclude that local in vivo bone remodelling can be successfully assessed with time-lapse in vivo HR-pQCT capable of assessing age-related changes in bone remodelling.
[Mh] Termos MeSH primário: Remodelação Óssea/fisiologia
Osso e Ossos/diagnóstico por imagem
Imagem com Lapso de Tempo/métodos
Tomografia Computadorizada por Raios X/métodos
[Mh] Termos MeSH secundário: Adulto
Idoso
Idoso de 80 Anos ou mais
Cadáver
Feminino
Seguimentos
Seres Humanos
Imagem Tridimensional/métodos
Masculino
Meia-Idade
Rádio (Anatomia)/diagnóstico por imagem
Reprodutibilidade dos Testes
Tíbia/diagnóstico por imagem
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180226
[Lr] Data última revisão:
180226
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180125
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0191369


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[PMID]:29352303
[Au] Autor:Gerli MFM; Guyette JP; Evangelista-Leite D; Ghoshhajra BB; Ott HC
[Ad] Endereço:Center for Regenerative Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America.
[Ti] Título:Perfusion decellularization of a human limb: A novel platform for composite tissue engineering and reconstructive surgery.
[So] Source:PLoS One;13(1):e0191497, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Muscle and fasciocutaneous flaps taken from autologous donor sites are currently the most utilized approach for trauma repair, accounting annually for 4.5 million procedures in the US alone. However, the donor tissue size is limited and the complications related to these surgical techniques lead to morbidities, often involving the donor sites. Alternatively, recent reports indicated that extracellular matrix (ECM) scaffolds boost the regenerative potential of the injured site, as shown in a small cohort of volumetric muscle loss patients. Perfusion decellularization is a bioengineering technology that allows the generation of clinical-scale ECM scaffolds with preserved complex architecture and with an intact vascular template, from a variety of donor organs and tissues. We recently reported that this technology is amenable to generate full composite tissue scaffolds from rat and non-human primate limbs. Translating this platform to human extremities could substantially benefit soft tissue and volumetric muscle loss patients providing tissue- and species-specific grafts. In this proof-of-concept study, we show the successful generation a large-scale, acellular composite tissue scaffold from a full cadaveric human upper extremity. This construct retained its morphological architecture and perfusable vascular conduits. Histological and biochemical validation confirmed the successful removal of nuclear and cellular components, and highlighted the preservation of the native extracellular matrix components. Our results indicate that perfusion decellularization can be applied to produce human composite tissue acellular scaffolds. With its preserved structure and vascular template, these biocompatible constructs, could have significant advantages over the currently implanted matrices by means of nutrient distribution, size-scalability and immunological response.
[Mh] Termos MeSH primário: Braço/cirurgia
Procedimentos Cirúrgicos Reconstrutivos/métodos
Engenharia Tecidual/métodos
Tecidos Suporte
[Mh] Termos MeSH secundário: Animais
Braço/anatomia & histologia
Braço/irrigação sanguínea
Reatores Biológicos
Cadáver
Matriz Extracelular/química
Seres Humanos
Imagem Tridimensional
Masculino
Meia-Idade
Perfusão
Ratos
Engenharia Tecidual/instrumentação
Tecidos Suporte/química
Microtomografia por Raio-X
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180226
[Lr] Data última revisão:
180226
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180121
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0191497


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[PMID]:28470459
[Au] Autor:Smolen C; Quenneville CE
[Ad] Endereço:Department of Mechanical Engineering, McMaster University, 1280 Main Street West, Hamilton, ON, L8S 4L7, Canada.
[Ti] Título:A Finite Element Model of the Foot/Ankle to Evaluate Injury Risk in Various Postures.
[So] Source:Ann Biomed Eng;45(8):1993-2008, 2017 08.
[Is] ISSN:1573-9686
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The foot/ankle complex is frequently injured in many types of debilitating events, such as car crashes. Numerical models used to assess injury risk are typically minimally validated and do not account for ankle posture variations that frequently occur during these events. The purpose of this study was to evaluate a finite element model of the foot and ankle accounting for these positional changes. A model was constructed from computed tomography scans of a male cadaveric lower leg and was evaluated by comparing simulated bone positions and strain responses to experimental results at five postures in which fractures are commonly reported. The bone positions showed agreement typically within 6° or less in all anatomical directions, and strain matching was consistent with the range of errors observed in similar studies (typically within 50% of the average strains). Fracture thresholds and locations in each posture were also estimated to be similar to those reported in the literature (ranging from 6.3 kN in the neutral posture to 3.9 kN in combined eversion and external rotation). The least vulnerable posture was neutral, and all other postures had lower fracture thresholds, indicating that examination of the fracture threshold of the lower limb in the neutral posture alone may be an underestimation. This work presents an important step forward in the modeling of lower limb injury risk in altered ankle postures. Potential clinical applications of the model include the development of postural guidelines to minimize injury, as well as the evaluation of new protective systems.
[Mh] Termos MeSH primário: Fraturas do Tornozelo/fisiopatologia
Traumatismos do Pé/fisiopatologia
Modelos Biológicos
Postura
Medição de Risco/métodos
Ossos do Tarso/lesões
Ossos do Tarso/fisiopatologia
[Mh] Termos MeSH secundário: Cadáver
Força Compressiva
Simulação por Computador
Módulo de Elasticidade
Análise de Elementos Finitos
Seres Humanos
Masculino
Meia-Idade
Amplitude de Movimento Articular
Estresse Mecânico
Resistência à Tração
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180215
[Lr] Data última revisão:
180215
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170505
[St] Status:MEDLINE
[do] DOI:10.1007/s10439-017-1844-2



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