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[PMID]:29466157
[Au] Autor:Brito LGO; Suto HS
[Ad] Endereço:University of Campinas, Campinas, Brazil lgobrito@gmail.com.
[Ti] Título:Hematometrocolpos in a Teenager.
[So] Source:N Engl J Med;378(8):e12, 2018 Feb 22.
[Is] ISSN:1533-4406
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Hematocolpia/diagnóstico por imagem
Hematometra/diagnóstico por imagem
[Mh] Termos MeSH secundário: Dor Abdominal/etiologia
Feminino
Hematocolpia/complicações
Hematometra/complicações
Seres Humanos
Hímen/anormalidades
Hímen/patologia
Distúrbios Menstruais/patologia
Dor Pélvica/etiologia
Tomografia Computadorizada por Raios X
Adulto Jovem
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180228
[Lr] Data última revisão:
180228
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180222
[St] Status:MEDLINE
[do] DOI:10.1056/NEJMicm1711730


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[PMID]:29381988
[Au] Autor:Zhou J; Yang L; Yu J; Wang Y; Liu Z
[Ad] Endereço:Department of Acupuncture, Guang'anmen Hospital, China Academy of Chinese Medical Sciences.
[Ti] Título:Efficacy of acupuncture on menstrual frequency in women with polycystic ovary syndrome: Protocol for a randomized, controlled trial.
[So] Source:Medicine (Baltimore);96(47):e8828, 2017 Nov.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Acupuncture may improve the menstrual frequency of women with polycystic ovary syndrome (PCOS). However, more sufficient data are needed to improve the efficacy of acupuncture. METHODS: A total of 172 participants diagnosed with PCOS would be randomly assigned to either the acupuncture group or sham-acupuncture group, at a ratio of 1:1. Participants in both groups will receive treatment for 12 weeks, 3 times a week. The primary outcome will be the proportion of participants with at least a 50% increase from baseline in the monthly menstrual frequency from baseline after 12 weeks intervention, while secondary outcomes will be the difference in anthropometrics, serum hormone level, ovarian morphology, anxiety and depression, and quality of life from baseline to after 12 weeks intervention and to 12 weeks postintervention follow-up between groups. DISCUSSION: The aim of this study is to evaluate the efficacy and safety of acupuncture for improving menstrual frequency and other symptoms of patients with PCOS. The limitation of this trial is that it would be difficult to blind the acupuncturists. In addition, these findings may not be suitable for women with PCOS who are seeking pregnancy.
[Mh] Termos MeSH primário: Terapia por Acupuntura/métodos
Ciclo Menstrual/fisiologia
Distúrbios Menstruais/terapia
Síndrome do Ovário Policístico/terapia
[Mh] Termos MeSH secundário: Adulto
Protocolos Clínicos
Método Duplo-Cego
Feminino
Seres Humanos
Distúrbios Menstruais/etiologia
Distúrbios Menstruais/fisiopatologia
Síndrome do Ovário Policístico/complicações
Síndrome do Ovário Policístico/fisiopatologia
Estudos Prospectivos
Qualidade de Vida
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180208
[Lr] Data última revisão:
180208
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180201
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000008828


  3 / 5993 MEDLINE  
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[PMID]:28911934
[Au] Autor:Osuga Y; Fujimoto-Okabe H; Hagino A
[Ad] Endereço:Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan. Electronic address: yutakaos-tky@umin.ac.jp.
[Ti] Título:Evaluation of the efficacy and safety of dienogest in the treatment of painful symptoms in patients with adenomyosis: a randomized, double-blind, multicenter, placebo-controlled study.
[So] Source:Fertil Steril;108(4):673-678, 2017 Oct.
[Is] ISSN:1556-5653
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To evaluate the efficacy and safety of dienogest (DNG), a progestational 19-norsteroid, in patients with symptomatic adenomyosis. DESIGN: Phase III, randomized, double-blind, multicenter, placebo-controlled study. SETTING: Clinical study sites in Japan. PATIENT(S): Sixty-seven patients with adenomyosis. INTERVENTION(S): Patients were randomly assigned to receive DNG (2 mg/d, orally) or placebo for 16 weeks. In cases of complicated anemia, patients were treated for anemia before randomization. MAIN OUTCOME MEASURE(S): The primary end point was the change from baseline to after treatment pain score, using zero- to three-point verbal rating scales that defined pain severity according to limited ability to work and need for analgesics. The visual analogue scale was used as another pain parameter. RESULT(S): Decreases from baseline in the pain score and the visual analogue scale at the end of treatment were significantly more in the DNG group than in the placebo group (P<.001). During the treatment period, almost all of the patients treated with DNG experienced irregular uterine bleeding and one patient had mild anemia. No severe cases of anemia were observed. CONCLUSION(S): These results suggest that DNG is effective and well tolerated in the treatment for painful symptoms associated with adenomyosis not complicated by severe uterine enlargement or severe anemia. CLINICAL TRIAL REGISTRATION NUMBER: JapicCTI-142642(en).
[Mh] Termos MeSH primário: Adenomiose/tratamento farmacológico
Nandrolona/análogos & derivados
Dor Pélvica/tratamento farmacológico
[Mh] Termos MeSH secundário: Adenomiose/complicações
Adulto
Método Duplo-Cego
Feminino
Seres Humanos
Japão
Distúrbios Menstruais/complicações
Distúrbios Menstruais/tratamento farmacológico
Meia-Idade
Nandrolona/uso terapêutico
Medição da Dor
Dor Pélvica/etiologia
Placebos
Índice de Gravidade de Doença
Resultado do Tratamento
Adulto Jovem
[Pt] Tipo de publicação:CLINICAL TRIAL, PHASE III; JOURNAL ARTICLE; MULTICENTER STUDY; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (Placebos); 46M3EV8HHE (dienogest); 6PG9VR430D (Nandrolone)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171013
[Lr] Data última revisão:
171013
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170916
[St] Status:MEDLINE


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[PMID]:28672284
[Au] Autor:Snook ML; Henry LC; Sanfilippo JS; Zeleznik AJ; Kontos AP
[Ad] Endereço:Department of Obstetrics, Gynecology, and Reproductive Sciences, Magee-Women's Hospital, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
[Ti] Título:Association of Concussion With Abnormal Menstrual Patterns in Adolescent and Young Women.
[So] Source:JAMA Pediatr;171(9):879-886, 2017 Sep 01.
[Is] ISSN:2168-6211
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Importance: Brain injury may interrupt menstrual patterns by altering hypothalamic-pituitary-ovarian axis function. Investigators have yet to evaluate the association of concussion with menstrual patterns in young women. Objective: To compare abnormal menstrual patterns in adolescent and young women after a sport-related concussion with those after sport-related orthopedic injuries to areas other than the head (nonhead). Design, Setting, and Participants: This prospective cohort study of adolescent and young women with a sport-related concussion (n = 68) or a nonhead sport-related orthopedic injury (n = 61) followed up participants for 120 days after injury. Patients aged 12 to 21 years who presented within 30 days after a sport-related injury to a concussion or sports medicine clinic at a single academic center were eligible. Menstrual patterns were assessed using a weekly text message link to an online survey inquiring about bleeding episodes each week. The first patient was enrolled on October 14, 2014, and follow-up was completed on January 24, 2016. Inclusion criteria required participants to be at least 2 years postmenarche, to report regular menses in the previous year, and to report no use of hormonal contraception. Exposures: Sport-related concussion or nonhead sport-related orthopedic injury. Main Outcomes and Measures: Abnormal menstrual patterns were defined by an intermenstrual interval of less than 21 days (short) or more than 35 days (long) or a bleeding duration of less than 3 days or more than 7 days. Results: A total of 1784 survey responses were completed of the 1888 text messages received by patients, yielding 487 menstrual patterns in 128 patients (mean [SD] age, 16.2 [2.0] years). Of the 68 patients who had a concussion, 16 (23.5%) experienced 2 or more abnormal menstrual patterns during the study period compared with 3 of 60 patients (5%) who had an orthopedic injury. Despite similar gynecologic age, body mass index, and type of sports participation between groups, the risk of 2 or more abnormal menstrual bleeding patterns after injury was significantly higher among patients with concussion than among those with an orthopedic injury (odds ratio, 5.85; 95% CI, 1.61-21.22). Conclusions and Relevance: Adolescent and young women may have increased risk of multiple abnormal menstrual patterns after concussion. Because abnormal menstrual patterns can have important health implications, monitoring menstrual patterns after concussion may be warranted in this population. Additional research is needed to elucidate the relationship between long-term consequences of concussion and the function of the hypothalamic-pituitary-ovarian axis.
[Mh] Termos MeSH primário: Traumatismos em Atletas/complicações
Concussão Encefálica/complicações
Distúrbios Menstruais/etiologia
[Mh] Termos MeSH secundário: Adolescente
Criança
Estudos de Coortes
Feminino
Seguimentos
Seres Humanos
Ciclo Menstrual
Distúrbios Menstruais/epidemiologia
Estudos Prospectivos
Fatores de Risco
Esportes
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170926
[Lr] Data última revisão:
170926
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170704
[St] Status:MEDLINE
[do] DOI:10.1001/jamapediatrics.2017.1140


  5 / 5993 MEDLINE  
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[PMID]:28566013
[Au] Autor:Romito P; Cedolin C; Bastiani F; Beltramini L; Saurel-Cubizolles MJ
[Ad] Endereço:1 Department of Life Sciences - Psychology Unit, University of Trieste, Trieste, Italy.
[Ti] Título:Sexual harassment and menstrual disorders among Italian university women: A cross-sectional observational study.
[So] Source:Scand J Public Health;45(5):528-535, 2017 Jul.
[Is] ISSN:1651-1905
[Cp] País de publicação:Sweden
[La] Idioma:eng
[Ab] Resumo:AIMS: Menstrual disorders and sexual harassment are common among young women and interfere with their life and activities. We aimed to describe the association of sexual harassment and menstrual disorders among female university students. METHODS: This cross-sectional, observational study examined the association between sexual harassment and menstrual disorders in a sample of 349 university students in Italy. Students answered an anonymous self-administered questionnaire. Descriptive bivariate analyses and logistic regression analyses were performed. Main outcome measures were associations between levels of exposure to sexual harassment (none, levels 1 and 2) and five menstrual disorders (premenstrual symptoms, heavy bleeding, pain, irregular cycles, and amenorrhea). RESULTS: Among the women interviewed (mean age 20.4 ± 1.45 years), 146 (41.8%) had experienced sexual harassment in the previous 12 months: 91 (26.1%) level 1 and 55 (15.7%) level 2. The frequency of premenstrual symptoms was 31.9% ( n=110); heavy bleeding, 35.3% ( n=124); pain, 51.4% ( n=181); irregular cycles, 55.5% ( n=195); and amenorrhea, 6.7% ( n=23). After adjustment for age, place of birth, being in a couple relationship and receiving hormone therapy, the frequency of menstrual disorders, except for amenorrhea, was increased with sexual harassment, with a regular gradient from no harassment to level 2 harassment. Introducing factors of depression, specific gynaecological problems and lifetime sexual violence did not change the results. For instance, the adjusted odds ratios of premenstrual symptoms were 2.10 [1.19-3.68] for women with level 1 harassment and 3.58 [1.83-7.03] for women with level 2 compared with women without harassment exposure. CONCLUSIONS: Sexual harassment is related to the prevalence of menstrual disorders. Healthcare providers should encourage dialogue with patients and address the issue of sexual violence or harassment.
[Mh] Termos MeSH primário: Distúrbios Menstruais/epidemiologia
Assédio Sexual/estatística & dados numéricos
Estudantes/estatística & dados numéricos
Universidades
[Mh] Termos MeSH secundário: Estudos Transversais
Feminino
Seres Humanos
Itália/epidemiologia
Inquéritos e Questionários
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; OBSERVATIONAL STUDY
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170706
[Lr] Data última revisão:
170706
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170602
[St] Status:MEDLINE
[do] DOI:10.1177/1403494817705559


  6 / 5993 MEDLINE  
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[PMID]:28538378
[Au] Autor:Cho GJ; Han SW; Shin JH; Kim T
[Ad] Endereço:aDepartment of Obstetrics and Gynecology, Korea University Anam Hospital, Korea University College of Medicine bSchool of Industrial Management Engineering, Korea University, Seoul, Republic of Korea.
[Ti] Título:Effects of intensive training on menstrual function and certain serum hormones and peptides related to the female reproductive system.
[So] Source:Medicine (Baltimore);96(21):e6876, 2017 May.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The aim of this study was to assess the effects of intensive training on menstrual function and related serum hormones and peptides.Forty female participants who attended a training course for an officer at the Korea Third Military Academy, and had regular menstrual periods were enrolled. Menstrual questionnaires and fasting blood samples were collected before entry and at 4-week intervals for 8 weeks. The levels of corticotropin-releasing hormone (CRH), cortisol, prolactin, endorphin-ß, neuropeptide Y (NPY), leptin, orexin-A, ghrelin, follicle-stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E2), thyrotropin (TSH), and thyroxine (T4) were determined.Body mass index and waist circumference decreased during the training course. Intensive training of military cadets resulted in changes of menstruation and related biomarkers. The levels of CRH, endorphin-ß, NPY, orexin-A, ghrelin, E2, and T4 decreased substantially, and cortisol, prolactin, and TSH increased. Seventy percent of participants with regular menstrual periods before developed irregular during the training course. Participants were then categorized into 2 groups: those with regular menstruation (n = 12) and those with irregular menstruation (n = 28). The levels of hormones and peptides were not different between the 2 groups.In conclusion, cortisol, prolactin, and TSH level increased but levels of CRH, endorphin-ß, NPY, orexin-A, ghrelin, E2, and T4 decreased throughout the training. Moreover, the levels were not different between participants with normal menstruation and those with irregular menstruation. Further research should extend these findings by investigating the exact mechanism by which high exercise levels, including intensive training, interfere with regular menstruation.
[Mh] Termos MeSH primário: Exercício/fisiologia
Hormônios Esteroides Gonadais/sangue
Distúrbios Menstruais/sangue
Menstruação/sangue
[Mh] Termos MeSH secundário: Adulto
Biomarcadores/sangue
Índice de Massa Corporal
Peso Corporal
Feminino
Seres Humanos
Militares
República da Coreia
Inquéritos e Questionários
Fatores de Tempo
Circunferência da Cintura
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; OBSERVATIONAL STUDY
[Nm] Nome de substância:
0 (Biomarkers); 0 (Gonadal Steroid Hormones)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170626
[Lr] Data última revisão:
170626
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170525
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000006876


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[PMID]:28472487
[Au] Autor:Turcu AF; Mallappa A; Elman MS; Avila NA; Marko J; Rao H; Tsodikov A; Auchus RJ; Merke DP
[Ad] Endereço:Division of Metabolism, Endocrinology and Diabetes, University of Michigan, Ann Arbor, Michigan 48109.
[Ti] Título:11-Oxygenated Androgens Are Biomarkers of Adrenal Volume and Testicular Adrenal Rest Tumors in 21-Hydroxylase Deficiency.
[So] Source:J Clin Endocrinol Metab;102(8):2701-2710, 2017 Aug 01.
[Is] ISSN:1945-7197
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Context: Patients with 21-hydroxylase deficiency (21OHD) have long-term complications, resulting from poor disease control and/or glucocorticoid overtreatment. Lack of optimal biomarkers has made it challenging to tailor therapy and predict long-term outcomes. Objective: To identify biomarkers of disease control and long-term complications in 21OHD. Setting and Participants: Cross-sectional study of 114 patients (70 males), ages 2 to 67 years (median, 15 years), seen in a tertiary referral center. Methods: We correlated a mass-spectrometry panel of 23 steroids, obtained before first morning medication, with bone age advancement (children), adrenal volume (adults), testicular adrenal rest tumors (TART), hirsutism, menstrual disorders, and pituitary hormones. Results: Total adrenal volume correlated positively with 18 steroids, most prominently 21-deoxycortisol and four 11-oxygenated-C19 (11oxC19) steroids: 11ß-hydroxyandrostenedione (11OHA4), 11-ketoandrostenedione (11ketoA4), 11ß-hydroxytestosterone (11OHT), and 11-ketotestosterone (11ketoT) (r ≈ 0.7, P < 0.0001). Nine steroids were significantly higher (P ≤ 0.01) in males with TART compared with those without TART, including 11OHA4 (6.8-fold), 11OHT (4.9-fold), 11ketoT (3.6-fold), 11ketoA4 (3.3-fold), and pregnenolone sulfate (PregS; 4.8-fold). PregS (28.5-fold) and 17-hydroxypregnenolone sulfate (19-fold) levels were higher (P < 0.01) in postpubertal females with menstrual disorders. In males, testosterone levels correlated positively with all 11oxC19 steroids in Tanner stages 1 and 2 (r ≈ 0.7; P < 0.001) but negatively in Tanner stage 5 (r = -0.3 and P < 0.05 for 11ketoA4 and 11ketoT). In females, testosterone level correlated positively with all four 11oxC19 steroids across all Tanner stages (r ≈ 0.8; P < 0.0001). Conclusion: 11oxC19 steroids and PregS might serve as clinically useful biomarkers of disease control and long-term complications in 21OHD.
[Mh] Termos MeSH primário: Hiperplasia Suprarrenal Congênita/metabolismo
Tumor de Resto Suprarrenal/metabolismo
Androgênios/metabolismo
Hirsutismo/metabolismo
Distúrbios Menstruais/metabolismo
Neoplasias Testiculares/metabolismo
[Mh] Termos MeSH secundário: 17-alfa-Hidroxipregnenolona/análogos & derivados
17-alfa-Hidroxipregnenolona/metabolismo
Adolescente
Glândulas Suprarrenais/patologia
Adulto
Determinação da Idade pelo Esqueleto
Idoso
Androstenodiona/análogos & derivados
Androstenodiona/metabolismo
Androstenos/metabolismo
Criança
Pré-Escolar
Cortodoxona/metabolismo
Estudos Transversais
Feminino
Seres Humanos
Hidroxitestosteronas/metabolismo
Masculino
Meia-Idade
Tamanho do Órgão
Pregnenolona/metabolismo
Testosterona/análogos & derivados
Testosterona/metabolismo
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Androgens); 0 (Androstenes); 0 (Hydroxytestosterones); 04Y4D91RG0 (pregnenolone sulfate); 1816-85-9 (11-hydroxytestosterone); 28901-70-4 (17-hydroxypregnenolone sulfate); 387-79-1 (17-alpha-Hydroxypregnenolone); 3XMK78S47O (Testosterone); 409J2J96VR (Androstenedione); 564-32-9 (11-hydroxyandrostenedione); 641-77-0 (21-deoxycortisol); 73R90F7MQ8 (Pregnenolone); AE4E9102GY (adrenosterone); KF38W1A85U (11-ketotestosterone); WDT5SLP0HQ (Cortodoxone)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170920
[Lr] Data última revisão:
170920
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170505
[St] Status:MEDLINE
[do] DOI:10.1210/jc.2016-3989


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[PMID]:28440522
[Au] Autor:Tang W; Chen Y; Pan M; Chen L; Zhang L; Wang T; Zhang X; Zhang P; Zheng C; Yu B
[Ad] Endereço:Department of Nutrition, Fudan University Pudong Medical Center, Shanghai 201399, China.
[Ti] Título:[Nutrition management in obese patients with type 2 diabetes mellitus after laparoscopic sleeve gastrectomy].
[So] Source:Zhonghua Wei Chang Wai Ke Za Zhi;20(4):411-416, 2017 Apr 25.
[Is] ISSN:1671-0274
[Cp] País de publicação:China
[La] Idioma:chi
[Ab] Resumo:OBJECTIVE: To explore the value of nutrition management in obese patients with type 2 diabetes mellitus(T2DM) after laparoscopic sleeve gastrectomy(LSG). METHODS: Clinical data of 22 obese T2DM patients undergoing LSG from March 2013 to July 2015 in Fudan University Pudong Medical Center were collected. All the patients strictly followed the specialized instruction by nutritionists: diabetic and low calorie diet 3347.2 to 5020.8 kJ (800 to 1200 kcal) per day before the operation; low calorie liquid diet 2510.4 kJ(600 kcal) per day before operation for promoting gastric emptying; fasting diet before postoperative ventilation; clear liquid diet 1673.6 to 2510.4 kJ (400 to 600 kcal) per day after postoperative ventilation (liquid intake >2000 ml); low fat liquid diet 2928.8 to 3765.6 kJ (700 to 900 kcal) per day (protein 60 g per day at least, 2000 ml liquid) 2 weeks after the operation; semi-liquid diet 1 month after operation and gradually normal diet. All the 22 patients were followed up at 1 week, 1, 3, 6 months after operation on time. Changes of body weight, waist circumference, hip circumference, body mass index(BMI), blood glucose indexes induding fasting blood glucose(FBG), 2-hour postparandial blood glucose(PBG), fasting C-peptide, 2-hour postprandial C-peptide, fasting serum inculin(FINS), 2-hour postprandial inculin(INS), HbAlc, blood pressure and blood lipid indexes were observed and analyzed before and 1 week, 1, 3, 6 months after operation. RESULTS: The average age of 22 patients (10 men and 12 women) was 38.6 years (18 to 66 years). The duration of diabetes varied from 1 month to 15 years. Comorbidity included 12 patients of high blood pressure, 14 of fatty liver, 1 of coronary heart disease, 1 of gout, 1 of chronic thyroiditis and 1 of menstrual disorder. LSG was performed successfully in all the patients and no severe complications and transference to laparotomy occurred. As compared to pre-operation, at 6 months after operation, the average body weight decreased from (103.9±20.2) kg to (80.9±12.6) kg (t=6.294, P=0.000), waist circumference from (118.6±13.8) cm to (96.4±8.0) cm (t=6.331, P=0.000), hip circumference from (116.9±12.6) cm to (104.0±7.7) cm (t=3.854, P=0.000), BMI from (36.2±5.9) kg/m to (27.9±3.5) kg/m (t=5.630, P=0.000), showing a decreasing trend over time. There was no underweight patient after 6 months follow-up. As compared to pre-operation, at 6 months after operation, the average FBG reduced from (7.4±1.4) mmol/L to (6.0±0.9) mmol/L (t=3.172, P=0.003), 2 h PBG from (14.1±4.9) mmol/L to (7.5±2.2) mmol/L (t=7.026, P=0.000), FINS from (160.0±71.9) mIU/L to (43.8±20.8) mIU/L (t=7.259, P=0.000), 2-hour postprandial INS from (437.6±261.4) mIU/L to (140.5±104.6) mIU/L (t=5.858, P=0.000), fasting C-peptide from (1.1±0.6) µg/L to (0.7±0.3) µg/L (t=3.560, P=0.000), 2-hour postprandial C-peptide from (2.5±0.9) µg/L to (1.5±0.7) µg/L (t=3.865, P=0.000), HbAlc from (8.0±1.6)% to (5.9±0.6)% (t=5.953, P=0.000), showing a decreasing trend over time except FBG, 2h postprandial C-peptide and HbAlc(all P<0.05). FBG and 2-hour PBG of 16 patients returned to normal 3 months after the operation. Blood pressure and trigly ceride decreased obviously 6 months after operation compared to pre-operation with significant difference(P<0.05). At 6 months after operation, blood pressure of 8 comorbidity patients with high blood pressure became normal (8/12, 66.7%) and of 4 patients improved(4/12, 33.3%); B ultrasound examination revealed normal in 11 comorbidity patients with fatty liver(11/14,78.6%) and improvement in 3 patients (3/14,15.4%). Blood uric acid of the gout patient and the menstruation of the menstrual disorder patient returned to normal 3 months and 1 month after the operation respectively. CONCLUSION: As for obese patients with T2DM undergoing LSG, reasonable nutrition management is helpful to decrease body weight, and to obtain an ideal improvement of blood glucose and blood lipid levels.
[Mh] Termos MeSH primário: Cirurgia Bariátrica
Glicemia/fisiologia
Diabetes Mellitus Tipo 2/terapia
Dietoterapia/métodos
Gastrectomia
Lipídeos/sangue
Lipídeos/fisiologia
Obesidade/terapia
Resultado do Tratamento
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Pesos e Medidas Corporais
Peptídeo C/sangue
Peptídeo C/fisiologia
Restrição Calórica
Terapia Combinada
Comorbidade
Doença das Coronárias/complicações
Diabetes Mellitus Tipo 2/complicações
Dieta para Diabéticos
Endoscopia
Fígado Gorduroso/complicações
Fígado Gorduroso/cirurgia
Feminino
Alimentos Formulados
Hemoglobina A Glicada/fisiologia
Gota/complicações
Gota/cirurgia
Doença de Hashimoto/complicações
Seres Humanos
Hipertensão/complicações
Hipertensão/cirurgia
Insulina/sangue
Insulina/fisiologia
Masculino
Distúrbios Menstruais/complicações
Distúrbios Menstruais/cirurgia
Meia-Idade
Obesidade/complicações
Assistência Perioperatória/métodos
Tireoidite/complicações
Triglicerídeos/sangue
Triglicerídeos/fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Blood Glucose); 0 (C-Peptide); 0 (Glycated Hemoglobin A); 0 (Insulin); 0 (Lipids); 0 (Triglycerides); 0 (hemoglobin A1c protein, human)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170426
[St] Status:MEDLINE


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[PMID]:28437145
[Au] Autor:Oates J
[Ad] Endereço:Florence Nightingale Faculty of Nursing & Midwifery, King's College London , London, United Kingdom .
[Ti] Título:The Effect of Yoga on Menstrual Disorders: A Systematic Review.
[So] Source:J Altern Complement Med;23(6):407-417, 2017 Jun.
[Is] ISSN:1557-7708
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To summarize and evaluate evidence for the effect of yoga on menstrual disorders. METHODS: PubMed, CINAHL/MEDLINE, Web of Science, AMED, and Scopus were searched for English-language literature relevant to the review question. All primary research studies were included. RESULTS: Fifteen studies described in 18 papers were included in the review. A range of yoga interventions were used. Some studies used a combination of Asana, Pranayama, and other yogic relaxation or meditation techniques. All included studies reported some change in their outcome measures, suggesting reduced symptoms of menstrual distress following a yoga intervention; however, the heterogeneity and intensity of the interventions and outcome measures meant that findings have limited generalizability and applicability in practice settings. CONCLUSIONS: Further research on the relationship between yoga practice and menstrual disorders is warranted, but there must be both consistency in the methods, measures, and quality of studies and a shift toward research on yoga practices that are replicable outside of the clinical trial setting.
[Mh] Termos MeSH primário: Distúrbios Menstruais/terapia
Ioga
[Mh] Termos MeSH secundário: Adolescente
Adulto
Ensaios Clínicos como Assunto
Feminino
Seres Humanos
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170626
[Lr] Data última revisão:
170626
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170425
[St] Status:MEDLINE
[do] DOI:10.1089/acm.2016.0363


  10 / 5993 MEDLINE  
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[PMID]:28350418
[Au] Autor:Salö M; Börjesson A
[Ad] Endereço:Skanes universitetssjukhus Lund - Barn- och ungdomskirurgiska kliniken, SUS Lund Lund, Sweden Skanes universitetssjukhus Lund - Barn- och ungdomskirurgiska kliniken Lund, Sweden.
[Ti] Título:Hymen imperforatus är en diagnos som ofta missas - Risk för långdragna symtom om adekvat undersökning inte genomförs..
[So] Source:Lakartidningen;114, 2017 Mar 23.
[Is] ISSN:1652-7518
[Cp] País de publicação:Sweden
[La] Idioma:swe
[Ab] Resumo:Imperforate hymen - an often missed diagnosis Imperforate hymen is the most common congenital malformation in the female reproduction system that give rise to obstructive symptoms. If the diagnosis is not made in the newborn girl, symptoms often first arise at menarche. The diagnosis is easy to make but has to be suspected. This case reports describes the typical clinical picture of a late diagnosed imperforate hymen. As shown in this case and from a review of the literature, these girls often have symptoms for a long time before the diagnosis is made. Further, they are often initially misdiagnosed, and a thorough history and examination is seldom performed despite repeated contacts with the primary care.
[Mh] Termos MeSH primário: Hímen/anormalidades
Distúrbios Menstruais/diagnóstico
[Mh] Termos MeSH secundário: Criança
Diagnóstico Tardio
Feminino
Seres Humanos
Hímen/diagnóstico por imagem
Hímen/cirurgia
Distúrbios Menstruais/diagnóstico por imagem
Distúrbios Menstruais/cirurgia
Risco
Ultrassonografia
[Pt] Tipo de publicação:CASE REPORTS
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170529
[Lr] Data última revisão:
170529
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170329
[St] Status:MEDLINE



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