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  1 / 2043 MEDLINE  
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[PMID]:28777827
[Au] Autor:Mazloumi Gavgani A; Hodgson DM; Nalivaiko E
[Ad] Endereço:School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, New South Wales, Australia.
[Ti] Título:Effects of visual flow direction on signs and symptoms of cybersickness.
[So] Source:PLoS One;12(8):e0182790, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Our objective was to assess the influence of visual flow direction on physiological changes and symptoms elicited by cybersickness. Twelve healthy subjects (6 male and 6 female) were exposed to a 15-min virtual ride on a rollercoaster on two different days in a counterbalanced manner, such half of participants were facing forward during the first ride while another half was facing backward. Forehead skin conductance, heart rate and HRV parameters (SDRR, RMSSD) were collected as objective measures; subjective symptoms were assessed with the Motion Sickness Assessment Questioner immediately after exposure. We found that while nausea ratings at which participants terminated the experiment did not differ between forward/backward rides, the mean ride tolerance time was significantly longer during reverse ride compared to forward ride (6.1±0.4 vs 5.0±0.5 min, respectively, p = 0.01, η2 = 0.45). Analysis of HRV parameters revealed significant reduction in both RMSSD (p = 0.02, t = 2.62, η2 = 0.43) and SDRR (p = 0.01, t = 2.90, η2 = 0.45) in the forward ride; no such changes were found in the backward ride. We also found that amplitude of phasic changes in forehead skin conductance increased significantly in both ride directions. This increase however was significantly lower (p<0.05) in backward ride when compared to the forward ride. When assessed immediately post-ride, subjects reported significantly lower (p = 0.04) subjective symptom intensity after the reverse ride compared to the forward ride. We conclude that the direction of visual flow has a significant effect on the symptoms reported by the subjects and on the physiological changes during cybersickness.
[Mh] Termos MeSH primário: Resposta Galvânica da Pele
Enjoo devido ao Movimento/fisiopatologia
Náusea/diagnóstico
Percepção Visual/fisiologia
[Mh] Termos MeSH secundário: Adulto
Feminino
Frequência Cardíaca
Seres Humanos
Masculino
Enjoo devido ao Movimento/complicações
Náusea/etiologia
Índice de Gravidade de Doença
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171010
[Lr] Data última revisão:
171010
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170805
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0182790


  2 / 2043 MEDLINE  
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[PMID]:28641681
[Au] Autor:Blue RS; Bonato F; Seaton K; Bubka A; Vardiman JL; Mathers C; Castleberry TL; Vanderploeg JM
[Ti] Título:The Effects of Training on Anxiety and Task Performance in Simulated Suborbital Spaceflight.
[So] Source:Aerosp Med Hum Perform;88(7):641-650, 2017 Jul 01.
[Is] ISSN:2375-6314
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: In commercial spaceflight, anxiety could become mission-impacting, causing negative experiences or endangering the flight itself. We studied layperson response to four varied-length training programs (ranging from 1 h-2 d of preparation) prior to centrifuge simulation of launch and re-entry acceleration profiles expected during suborbital spaceflight. We examined subject task execution, evaluating performance in high-stress conditions. We sought to identify any trends in demographics, hemodynamics, or similar factors in subjects with the highest anxiety or poorest tolerance of the experience. METHODS: Volunteers participated in one of four centrifuge training programs of varied complexity and duration, culminating in two simulated suborbital spaceflights. At most, subjects underwent seven centrifuge runs over 2 d, including two +Gz runs (peak +3.5 Gz, Run 2) and two +Gx runs (peak +6.0 Gx, Run 4) followed by three runs approximating suborbital spaceflight profiles (combined +Gx and +Gz, peak +6.0 Gx and +4.0 Gz). Two cohorts also received dedicated anxiety-mitigation training. Subjects were evaluated on their performance on various tasks, including a simulated emergency. RESULTS: Participating in 2-7 centrifuge exposures were 148 subjects (105 men, 43 women, age range 19-72 yr, mean 39.4 ± 13.2 yr, body mass index range 17.3-38.1, mean 25.1 ± 3.7). There were 10 subjects who withdrew or limited their G exposure; history of motion sickness was associated with opting out. Shorter length training programs were associated with elevated hemodynamic responses. Single-directional G training did not significantly improve tolerance. DISCUSSION: Training programs appear best when high fidelity and sequential exposures may improve tolerance of physical/psychological flight stressors. The studied variables did not predict anxiety-related responses to these centrifuge profiles.Blue RS, Bonato F, Seaton K, Bubka A, Vardiman JL, Mathers C, Castleberry TL, Vanderploeg JM. The effects of training on anxiety and task performance in simulated suborbital spaceflight. Aerosp Med Hum Perform. 2017; 88(7):641-650.
[Mh] Termos MeSH primário: Ansiedade/psicologia
Voo Espacial
Simulação de Ambiente Espacial/métodos
Análise e Desempenho de Tarefas
[Mh] Termos MeSH secundário: Adulto
Medicina Aeroespacial
Idoso
Centrifugação
Estudos de Coortes
Feminino
Hemodinâmica
Seres Humanos
Masculino
Meia-Idade
Enjoo devido ao Movimento
Estudos Prospectivos
Simulação de Ambiente Espacial/psicologia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170829
[Lr] Data última revisão:
170829
[Sb] Subgrupo de revista:IM; S
[Da] Data de entrada para processamento:170624
[St] Status:MEDLINE
[do] DOI:10.3357/AMHP.4807.2017


  3 / 2043 MEDLINE  
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[PMID]:28380077
[Au] Autor:Nooij SA; Pretto P; Oberfeld D; Hecht H; Bülthoff HH
[Ad] Endereço:Department of Human Perception Cognition and Action, Max Planck Institute for Biological Cybernetics, Tübingen, Germany.
[Ti] Título:Vection is the main contributor to motion sickness induced by visual yaw rotation: Implications for conflict and eye movement theories.
[So] Source:PLoS One;12(4):e0175305, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:This study investigated the role of vection (i.e., a visually induced sense of self-motion), optokinetic nystagmus (OKN), and inadvertent head movements in visually induced motion sickness (VIMS), evoked by yaw rotation of the visual surround. These three elements have all been proposed as contributing factors in VIMS, as they can be linked to different motion sickness theories. However, a full understanding of the role of each factor is still lacking because independent manipulation has proven difficult in the past. We adopted an integrative approach to the problem by obtaining measures of potentially relevant parameters in four experimental conditions and subsequently combining them in a linear mixed regression model. To that end, participants were exposed to visual yaw rotation in four separate sessions. Using a full factorial design, the OKN was manipulated by a fixation target (present/absent), and vection strength by introducing a conflict in the motion direction of the central and peripheral field of view (present/absent). In all conditions, head movements were minimized as much as possible. Measured parameters included vection strength, vection variability, OKN slow phase velocity, OKN frequency, the number of inadvertent head movements, and inadvertent head tilt. Results show that VIMS increases with vection strength, but that this relation varies among participants (R2 = 0.48). Regression parameters for vection variability, head and eye movement parameters were not significant. These results may seem to be in line with the Sensory Conflict theory on motion sickness, but we argue that a more detailed definition of the exact nature of the conflict is required to fully appreciate the relationship between vection and VIMS.
[Mh] Termos MeSH primário: Movimentos Oculares/fisiologia
Enjoo devido ao Movimento/etiologia
[Mh] Termos MeSH secundário: Adulto
Feminino
Movimentos da Cabeça/fisiologia
Seres Humanos
Masculino
Meia-Idade
Modelos Biológicos
Movimento (Física)
Enjoo devido ao Movimento/fisiopatologia
Nistagmo Optocinético/fisiologia
Rotação/efeitos adversos
Percepção Visual/fisiologia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170906
[Lr] Data última revisão:
170906
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170406
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0175305


  4 / 2043 MEDLINE  
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[PMID]:28357830
[Au] Autor:Carron M; Coulange M; Dupuy C; Mastalski P; Barberon B; Roullaud A; Desplantes A; Auffray JP
[Ad] Endereço:Emergency Department, Pasteur 2 University Hospital, Nice, France. mathieu.carron01@gmail.com.
[Ti] Título:Preparation and medical follow-up for a single-handed transatlantic rowing race.
[So] Source:Int Marit Health;68(1):7-11, 2017.
[Is] ISSN:2081-3252
[Cp] País de publicação:Poland
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: A single-handed transatlantic rowing race was organised between Senegal and French Guyana (2600 nautical miles). During the race, rowers adjust their lifestyle to maintain an optimal level of performance. Nutrition, circadian rhythm disturbance, psychological state, pain and other medical problems impact on physical abilities and increase the occurrence of accidents. We surveyed the prevalence of medical complications during this race and the preparation that we could suggest for this kind of activity. MATERIALS AND METHODS: This is a descriptive, retrospective case series study. Follow-up consisted of sending out a questionnaire and performing individual interviews. RESULTS: A total of 23 participants including 1 woman and 22 men; mean age of 46.5 years (range: 35-59) entered the race. The race lasted for 39 to 52 days with participants rowing between 10 and 12 h/day. Nine participants dropped out. Energy intake was 4500 to 6000 kcal/day and fluid intake was 4 to 5.5 L/day. Mean weight loss was 13.3 kg. The resting period was 6 ± 1 h/24 h divided into 1.5 to 2 h periods essentially during darkness. A total of 92% of the racers required medical care for dermatological problems; other conditions requiring medical care were: tendinitis in 10 cases, diarrhoea in 4, moderate to severe seasickness in 4, hallucinations in 3, panic attacks in 2, burns in 2, and disembarkation syndrome ("land sickness") lasting from 45 min to 6 h in 13. CONCLUSIONS: Physiological and psychological impact of this type of event is still unclear. The most common medical problems are dermatological, rheumatological complications and minor trauma. Medical and psychological preparation should be offered to candidates for these competitions.
[Mh] Termos MeSH primário: Dermatopatias/epidemiologia
Medicina Esportiva/métodos
[Mh] Termos MeSH secundário: Adulto
Oceano Atlântico
Feminino
Seguimentos
Seres Humanos
Masculino
Meia-Idade
Enjoo devido ao Movimento/epidemiologia
Medicina Naval
Estado Nutricional
Estudos Retrospectivos
Sono
Medicina Esportiva/estatística & dados numéricos
Ferimentos e Lesões/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170920
[Lr] Data última revisão:
170920
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170331
[St] Status:MEDLINE
[do] DOI:10.5603/IMH.2017.0002


  5 / 2043 MEDLINE  
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[PMID]:28245927
[Au] Autor:Toschi N; Kim J; Sclocco R; Duggento A; Barbieri R; Kuo B; Napadow V
[Ad] Endereço:Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA.
[Ti] Título:Motion sickness increases functional connectivity between visual motion and nausea-associated brain regions.
[So] Source:Auton Neurosci;202:108-113, 2017 Jan.
[Is] ISSN:1872-7484
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:The brain networks supporting nausea not yet understood. We previously found that while visual stimulation activated primary (V1) and extrastriate visual cortices (MT+/V5, coding for visual motion), increasing nausea was associated with increasing sustained activation in several brain areas, with significant co-activation for anterior insula (aIns) and mid-cingulate (MCC) cortices. Here, we hypothesized that motion sickness also alters functional connectivity between visual motion and previously identified nausea-processing brain regions. Subjects prone to motion sickness and controls completed a motion sickness provocation task during fMRI/ECG acquisition. We studied changes in connectivity between visual processing areas activated by the stimulus (MT+/V5, V1), right aIns and MCC when comparing rest (BASELINE) to peak nausea state (NAUSEA). Compared to BASELINE, NAUSEA reduced connectivity between right and left V1 and increased connectivity between right MT+/V5 and aIns and between left MT+/V5 and MCC. Additionally, the change in MT+/V5 to insula connectivity was significantly associated with a change in sympathovagal balance, assessed by heart rate variability analysis. No state-related connectivity changes were noted for the control group. Increased connectivity between a visual motion processing region and nausea/salience brain regions may reflect increased transfer of visual/vestibular mismatch information to brain regions supporting nausea perception and autonomic processing. We conclude that vection-induced nausea increases connectivity between nausea-processing regions and those activated by the nauseogenic stimulus. This enhanced low-frequency coupling may support continual, slowly evolving nausea perception and shifts toward sympathetic dominance. Disengaging this coupling may be a target for biobehavioral interventions aimed at reducing motion sickness severity.
[Mh] Termos MeSH primário: Encéfalo/fisiopatologia
Percepção de Movimento/fisiologia
Enjoo devido ao Movimento/fisiopatologia
Náusea/fisiopatologia
[Mh] Termos MeSH secundário: Adulto
Encéfalo/diagnóstico por imagem
Mapeamento Encefálico
Circulação Cerebrovascular/fisiologia
Eletrocardiografia
Feminino
Frequência Cardíaca/fisiologia
Seres Humanos
Imagem por Ressonância Magnética
Enjoo devido ao Movimento/diagnóstico por imagem
Náusea/diagnóstico por imagem
Vias Neurais/diagnóstico por imagem
Vias Neurais/fisiopatologia
Oxigênio/sangue
Estimulação Luminosa
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
S88TT14065 (Oxygen)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:171102
[Lr] Data última revisão:
171102
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170302
[St] Status:MEDLINE
[do] DOI:10.1016/j.autneu.2016.10.003


  6 / 2043 MEDLINE  
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[PMID]:28222642
[Au] Autor:Semiz A; Akpak YK; Yilanlioglu NC; Babacan A; Gönen G; Çam Gönen C; Asiliskender M; Karaküçük S
[Ad] Endereço:1 Memorial Hospital, Fetal Medicine and Perinatology Unit, Istanbul, Turkey.
[Ti] Título:Prediction of intraoperative nausea and vomiting in caesarean delivery under regional anaesthesia.
[So] Source:J Int Med Res;45(1):332-339, 2017 Feb.
[Is] ISSN:1473-2300
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Objectives This study aimed to predict patients who have caesarean operations under regional anaesthesia and are at risk for intraoperative nausea and vomiting (IONV), for ultimately prompting anaesthetists and surgeons to take preventive measures. Methods This was a retrospective study on 209 patients who had caesarean section under spinal-epidural combined regional anaesthesia. The relevant medical history, such as severe nausea and vomiting in the first trimester, smoking, a history of motion sickness, and premenstrual syndrome (PMS), were obtained from the patients' records and interviews. Results Patients who had a female neonate, a history of severe nausea and vomiting in the first trimester, and a history of PMS and motion sickness before pregnancy experienced a significantly higher rate of IONV. Smokers were less susceptible to IONV, but this was not significant. Conclusion This study shows that some factors in the medical history of a patient can help identify those who are more likely to suffer from IONV.
[Mh] Termos MeSH primário: Anestesia por Condução
Antieméticos/uso terapêutico
Cesárea/efeitos adversos
Náusea e Vômito Pós-Operatório/diagnóstico
Náusea e Vômito Pós-Operatório/prevenção & controle
[Mh] Termos MeSH secundário: Adulto
Anestesia Obstétrica
Raquianestesia
Método Duplo-Cego
Feminino
Seres Humanos
Recém-Nascido
Masculino
Enjoo devido ao Movimento/fisiopatologia
Náusea e Vômito Pós-Operatório/etiologia
Náusea e Vômito Pós-Operatório/fisiopatologia
Gravidez
Síndrome Pré-Menstrual/fisiopatologia
Prognóstico
Estudos Retrospectivos
Fatores de Risco
Fatores Sexuais
Fumar/fisiopatologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; MULTICENTER STUDY
[Nm] Nome de substância:
0 (Antiemetics)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:171004
[Lr] Data última revisão:
171004
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170223
[St] Status:MEDLINE
[do] DOI:10.1177/0300060516680547


  7 / 2043 MEDLINE  
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[PMID]:28117179
[Au] Autor:Bounes V; Charriton-Dadone B; Levraut J; Delangue C; Carpentier F; Mary-Chalon S; Houze-Cerfon V; Sommet A; Houze-Cerfon CH; Ganetsky M
[Ad] Endereço:Pôle Médecine d'Urgence, Hôpital Universitaire de Purpan, Toulouse 31059 Cedex 9, France; INSERM UMR 1027, Université Paul Sabatier, Toulouse 31000, France. Electronic address: bounes.v@chu-toulouse.fr.
[Ti] Título:Predicting morphine related side effects in the ED: An international cohort study.
[So] Source:Am J Emerg Med;35(4):531-535, 2017 Apr.
[Is] ISSN:1532-8171
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:STUDY OBJECTIVES: Morphine is the reference treatment for severe acute pain in an emergency department. The purpose of this study was to describe and analyse opioid-related ADRs (adverse drug reactions) in a large cohort of emergency department patients, and to identify predictive factors for those ADRs. METHODS: In this prospective, observational, pharmaco-epidemiological international cohort study, all patients aged 18years or older who were treated with morphine were enrolled. The study was done in 23 emergency departments in the US and France. Baseline numerical rating scale score and initial and total doses of morphine titration were recorded. Logistic regression analysis was used to study the effects of demographic, clinical and medical history covariates on the occurrence of opioid-induced ADRs within 6h after treatment. RESULTS: A total of 1128 patients were included over 10months. Median baseline initial pain scores were 8/10 (7-10) versus 3/10 (1-4) after morphine administration. Median titration duration was 10min (IQR, 1-30). The occurrence of opioid-induced ADRs was 25% and 2% were serious. Patients experienced mainly nausea and drowsiness. Medical history of travel sickness (odds ratio [OR], 1.7; 95% confidence interval [CI], 1.01-2.86) and history of nausea or vomiting post morphine (OR, 3.86; 95% CI, 2.29-6.51) were independent predictors of morphine related ADRs. CONCLUSION: Serious morphine related ADRs are rare and unpredictable. Prophylactic antiemetic therapy could be proposed to patients with history of travel sickness and history of nausea or vomiting in a postoperative setting or after morphine administration.
[Mh] Termos MeSH primário: Dor Aguda/tratamento farmacológico
Acatisia Induzida por Medicamentos/etiologia
Analgésicos Opioides/efeitos adversos
Morfina/efeitos adversos
Náusea/induzido quimicamente
Prurido/induzido quimicamente
Vômito/induzido quimicamente
[Mh] Termos MeSH secundário: Adulto
Idoso
Acatisia Induzida por Medicamentos/epidemiologia
Estudos de Coortes
Serviço Hospitalar de Emergência
Feminino
França/epidemiologia
Seres Humanos
Modelos Logísticos
Masculino
Meia-Idade
Enjoo devido ao Movimento/epidemiologia
Análise Multivariada
Náusea/epidemiologia
Razão de Chances
Farmacoepidemiologia
Estudos Prospectivos
Prurido/epidemiologia
Fatores de Risco
Fases do Sono
Estados Unidos/epidemiologia
Vômito/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; MULTICENTER STUDY; OBSERVATIONAL STUDY
[Nm] Nome de substância:
0 (Analgesics, Opioid); 76I7G6D29C (Morphine)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170417
[Lr] Data última revisão:
170417
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170125
[St] Status:MEDLINE


  8 / 2043 MEDLINE  
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[PMID]:28061915
[Au] Autor:Golding JF; Paillard AC; Normand H; Besnard S; Denise P
[Ti] Título:Prevalence, Predictors, and Prevention of Motion Sickness in Zero-G Parabolic Flights.
[So] Source:Aerosp Med Hum Perform;88(1):3-9, 2017 Jan 01.
[Is] ISSN:2375-6314
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: Zero-G parabolic flight reproduces the weightlessness of space for short periods. However, motion sickness may affect some fliers. The aim was to assess the extent of this problem and to find possible predictors and modifying factors. METHODS: Airbus zero-G flights consist of 31 parabolas performed in blocks. Each parabola consisted of 20 s of 0 g sandwiched by 20 s of hypergravity of 1.5-1.8 g. The survey covered N = 246 person-flights (193 men, 53 women), ages (M ± SD) 36.0 ± 11.3 yr. An anonymous questionnaire included motion sickness rating (1 = OK to 6 = vomiting), Motion Sickness Susceptibility Questionnaire (MSSQ), antimotion sickness medication, prior zero-G experience, anxiety level, and other characteristics. RESULTS: Participants had lower MSSQ percentile scores (27.4 ± 28.0) than the population norm of 50. Motion sickness was experienced by 33% and 12% vomited. Less motion sickness was predicted by older age, greater prior zero-G flight experience, medication with scopolamine, lower MSSQ scores, but not gender or anxiety. Sickness ratings in fliers pretreated with scopolamine (1.81 ± 1.58) were lower than for nonmedicated fliers (2.93 ± 2.16), and incidence of vomiting in fliers using scopolamine treatment was reduced by half to a third. Possible confounding factors including age, sex, flight experience, and MSSQ could not account for this. CONCLUSION: Motion sickness affected one-third of zero-G fliers despite being intrinsically less motion sickness susceptible compared to the general population. Susceptible individuals probably try to avoid such a provocative environment. Risk factors for motion sickness included younger age and higher MSSQ scores. Protective factors included prior zero-G flight experience (habituation) and antimotion sickness medication.Golding JF, Paillard AC, Normand H, Besnard S, Denise P. Prevalence, predictors, and prevention of motion sickness in zero-G parabolic flights. Aerosp Med Hum Perform. 2017; 88(1):3-9.
[Mh] Termos MeSH primário: Ansiedade/epidemiologia
Antagonistas Colinérgicos/uso terapêutico
Enjoo devido ao Movimento/epidemiologia
Simulação de Ausência de Peso
[Mh] Termos MeSH secundário: Adulto
Fatores Etários
Feminino
Habituação Psicofisiológica
Seres Humanos
Masculino
Meia-Idade
Enjoo devido ao Movimento/prevenção & controle
Náusea/epidemiologia
Náusea/prevenção & controle
Prevalência
Fatores de Proteção
Fatores de Risco
Hidrobrometo de Escopolamina/uso terapêutico
Índice de Gravidade de Doença
Fatores Sexuais
Inquéritos e Questionários
Vômito/epidemiologia
Vômito/prevenção & controle
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Cholinergic Antagonists); 451IFR0GXB (Scopolamine Hydrobromide)
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170221
[Lr] Data última revisão:
170221
[Sb] Subgrupo de revista:IM; S
[Da] Data de entrada para processamento:170108
[St] Status:MEDLINE
[do] DOI:10.3357/AMHP.4705.2017


  9 / 2043 MEDLINE  
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[PMID]:28010995
[Au] Autor:Gavgani AM; Nesbitt KV; Blackmore KL; Nalivaiko E
[Ad] Endereço:School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, NSW 2300, Australia.
[Ti] Título:Profiling subjective symptoms and autonomic changes associated with cybersickness.
[So] Source:Auton Neurosci;203:41-50, 2017 Mar.
[Is] ISSN:1872-7484
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Our aim was to expand knowledge of cybersickness - a subtype of motion sickness provoked by immersion into a moving computer-generated virtual reality. Fourteen healthy subjects experienced a 15-min rollercoaster ride presented via a head-mounted display (Oculus Rift), for 3 consecutive days. Heart rate, respiration, finger and forehead skin conductance were measured during the experiment; this was complemented by a subjective nausea rating during the ride and by Motion Sickness Assessment Questionnaire before, immediately after and then 1, 2 and 3h post-ride. Physiological measurements were analysed in three dimensions: ride time, association with subjective nausea rating and experimental day. Forehead, and to a lesser extent finger phasic skin conductance activity showed a correlation with the reported nausea ratings, while alteration in other measured parameters were mostly related to autonomic arousal during the virtual ride onset. A significant habituation was observed in subjective symptom scores and in the duration of tolerated provocation. The latter increased from 7.0±1.3min on the first day to 12.0±2.5min on the third day (p<0.05); this was associated with a reduced slope of nausea rise from 1.3±0.3units/min on the first to 0.7±0.1units/min on the third day (p<0.01). Furthermore, habituation with repetitive exposure was also determined in the total symptom score post-ride: it fell from 1.6±0.1 on the first day to 1.2±0.1 on the third (p<0.001). We conclude that phasic changes of skin conductance on the forehead could be used to objectively quantify nausea; and that repetitive exposure to provocative VR content results in habituation.
[Mh] Termos MeSH primário: Sistema Nervoso Autônomo/fisiopatologia
Enjoo devido ao Movimento/fisiopatologia
Interface Usuário-Computador
[Mh] Termos MeSH secundário: Adulto
Análise de Variância
Nível de Alerta/fisiologia
Eletrocardiografia
Feminino
Dedos/fisiopatologia
Testa/fisiopatologia
Resposta Galvânica da Pele
Habituação Psicofisiológica
Frequência Cardíaca
Seres Humanos
Masculino
Respiração
Índice de Gravidade de Doença
Inquéritos e Questionários
Fatores de Tempo
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170821
[Lr] Data última revisão:
170821
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161225
[St] Status:MEDLINE


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[PMID]:27918236
[Au] Autor:Golding JF; Patel M
[Ad] Endereço:a Department of Psychology, Faculty of Science and Technology , University of Westminster , London , UK.
[Ti] Título:Meniere's, migraine, and motion sickness.
[So] Source:Acta Otolaryngol;137(5):495-502, 2017 May.
[Is] ISSN:1651-2251
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:CONCLUSION: Elevated Motion Sickness Susceptibility (MSS) in Meniere?s disease (MD) is likely to be a consequence of the onset of MD and not migraine per se. OBJECTIVES: Pathologies of the vestibular system influence MSS. Bilateral vestibular deficits lower MSS, vestibular neuritis or benign paroxysmal positional vertigo have little overall effect, whereas vestibular migraine elevates MSS. However, less is known about MSS in MD, a condition in which many patients experience vestibular loss and migraine symptoms. METHODS: The authors conducted an online survey that posed diagnostic and disease questions before addressing frequency of headaches, migraines, visual display dizziness (VDD), syncope, social life, and work impact of dizziness (SWID4) and motion sickness susceptibility (MSSQ). The two groups were: diagnosed MD individuals with hearing loss (n = 751) and non-MD individuals in the control group (n = 400). RESULTS: The MD group showed significantly elevated MSS, more headache and migraine, increased VDD, higher SWID4 scores, and increased syncope. MSS was higher in MD than controls only after the development of MD, but not before, nor in childhood. Although elevated in MD compared with controls, MSS was lower than migraine patients from past data. Multivariate analysis revealed VDD, SWID4, and MSS in adulthood as the strongest predictors of MD, but not headache nor migraine.
[Mh] Termos MeSH primário: Doença de Meniere/complicações
Transtornos de Enxaqueca/complicações
Enjoo devido ao Movimento/etiologia
[Mh] Termos MeSH secundário: Adulto
Estudos de Casos e Controles
Feminino
Seres Humanos
Masculino
Doença de Meniere/epidemiologia
Meia-Idade
Inquéritos e Questionários
Reino Unido/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170623
[Lr] Data última revisão:
170623
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161206
[St] Status:MEDLINE
[do] DOI:10.1080/00016489.2016.1255775



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