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[PMID]:28459248
[Au] Autor:Germain L; Malcmacher L
[Ad] Endereço:Faculty, American Academy of Facial Esthetics; Private Practice, New Orleans, Louisiana.
[Ti] Título:Frontline Temporomandibular Joint/Orofacial Pain Therapy for Every Dental Practice.
[So] Source:Compend Contin Educ Dent;38(5):299-305; quiz 306, 2017 May.
[Is] ISSN:2158-1797
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Temporomandibular disorders (TMD) are a group of conditions affecting the temporomandibular joint and/or muscles of mastication. TMD may present along with many comorbid pain syndromes such as myofascial pain, headache, and neck and back stiffness with limited range of motion, as well as fibromyalgia and chronic fatigue syndrome. The diagnosis and management of TMD is complex and, many times, multidisciplinary. However, dentists can provide their patients with frontline temporomandibular/orofacial pain therapy with didactic and hands-on training that provides a better understanding and a conservative approach for treatment of TMDs.
[Mh] Termos MeSH primário: Dor Facial/terapia
Transtornos da Articulação Temporomandibular/terapia
[Mh] Termos MeSH secundário: Toxinas Botulínicas Tipo A/uso terapêutico
Dor Facial/etiologia
Seres Humanos
Transtornos da Articulação Temporomandibular/classificação
Transtornos da Articulação Temporomandibular/diagnóstico
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
EC 3.4.24.69 (Botulinum Toxins, Type A)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:D
[Da] Data de entrada para processamento:170502
[St] Status:MEDLINE


  2 / 5686 MEDLINE  
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[PMID]:29184209
[Au] Autor:Rodriguez E; Sakurai K; Xu J; Chen Y; Toda K; Zhao S; Han BX; Ryu D; Yin H; Liedtke W; Wang F
[Ad] Endereço:Department of Neurobiology, Duke University Medical Center, Durham, NC, USA.
[Ti] Título:A craniofacial-specific monosynaptic circuit enables heightened affective pain.
[So] Source:Nat Neurosci;20(12):1734-1743, 2017 Dec.
[Is] ISSN:1546-1726
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Humans often rank craniofacial pain as more severe than body pain. Evidence suggests that a stimulus of the same intensity induces stronger pain in the face than in the body. However, the underlying neural circuitry for the differential processing of facial versus bodily pain remains unknown. Interestingly, the lateral parabrachial nucleus (PB ), a critical node in the affective pain circuit, is activated more strongly by noxious stimulation of the face than of the hindpaw. Using a novel activity-dependent technology called CANE developed in our laboratory, we identified and selectively labeled noxious-stimulus-activated PB neurons and performed comprehensive anatomical input-output mapping. Surprisingly, we uncovered a hitherto uncharacterized monosynaptic connection between cranial sensory neurons and the PB -nociceptive neurons. Optogenetic activation of this monosynaptic craniofacial-to-PB projection induced robust escape and avoidance behaviors and stress calls, whereas optogenetic silencing specifically reduced facial nociception. The monosynaptic circuit revealed here provides a neural substrate for heightened craniofacial affective pain.
[Mh] Termos MeSH primário: Dor Facial/fisiopatologia
Dor Facial/psicologia
Nociceptores
Sinapses
[Mh] Termos MeSH secundário: Afeto
Vias Aferentes/fisiopatologia
Animais
Comportamento Animal
Condicionamento Operante
Feminino
Genes fos/genética
Masculino
Camundongos
Camundongos Endogâmicos C57BL
Optogenética
Estimulação Física
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1712
[Cu] Atualização por classe:180222
[Lr] Data última revisão:
180222
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171130
[St] Status:MEDLINE
[do] DOI:10.1038/s41593-017-0012-1


  3 / 5686 MEDLINE  
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[PMID]:28456767
[Au] Autor:Almeida RT; Galdino G; Perez AC; Silva G; Romero TR; Duarte ID
[Ad] Endereço:Department of Pharmacology, Institute of Biological Sciences, Federal University of Belo Horizonte, Minas Gerais, Brazil. imitri@icb.ufmg.br.
[Ti] Título:St36 electroacupuncture activates nNOS, iNOS and ATP-sensitive potassium channels to promote orofacial antinociception in rats.
[So] Source:J Physiol Pharmacol;68(1):27-33, 2017 Feb.
[Is] ISSN:1899-1505
[Cp] País de publicação:Poland
[La] Idioma:eng
[Ab] Resumo:Orofacial pain is pain perceived in the face and/or oral cavity, generally caused by diseases or disorders of regional structures, by dysfunction of the nervous system, or through referral from distant sources. Treatment of orofacial pain is mainly pharmacological, but it has increased the number of reports demonstrating great clinical results with the use of non-pharmacological therapies, among them electroacupuncture. However, the mechanisms involved in the electroacupuncture are not well elucidated. Thus, the present study investigate the involvement of the nitric oxide synthase (NOS) and ATP sensitive K channels (KATP) in the antinociception induced by electroacupuncture (EA) at acupoint St36. Thermal nociception was applied in the vibrissae region of rats, and latency time for face withdrawal was measured. Electrical stimulation of acupoint St36 for 20 minutes reversed the thermal withdrawal latency and this effect was maintained for 150 min. Intraperitoneal administration of specific inhibitors of neuronal nitric oxide synthase (nNOS), inducible nitric oxide synthase (iNOS) and a KATP channels blocker reversed the antinociception induced by EA. Furthermore, nitrite concentration in cerebrospinal fluid (CSF) and plasma, increased 4 and 3-fold higher, respectively, after EA. This study suggests that NO participates of antinociception induced by EA by nNOS, iNOS and ATP-sensitive K channels activation.
[Mh] Termos MeSH primário: Pontos de Acupuntura
Eletroacupuntura
Dor Facial/terapia
Manejo da Dor
[Mh] Termos MeSH secundário: Animais
Dor Facial/fisiopatologia
Temperatura Alta/efeitos adversos
Canais KATP/antagonistas & inibidores
Canais KATP/fisiologia
Masculino
Óxido Nítrico Sintase Tipo I/antagonistas & inibidores
Óxido Nítrico Sintase Tipo I/fisiologia
Óxido Nítrico Sintase Tipo II/antagonistas & inibidores
Óxido Nítrico Sintase Tipo II/fisiologia
Nitritos/sangue
Nitritos/líquido cefalorraquidiano
Ratos Wistar
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (KATP Channels); 0 (Nitrites); EC 1.14.13.39 (Nitric Oxide Synthase Type I); EC 1.14.13.39 (Nitric Oxide Synthase Type II); EC 1.14.13.39 (Nos2 protein, rat)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180220
[Lr] Data última revisão:
180220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170501
[St] Status:MEDLINE


  4 / 5686 MEDLINE  
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[PMID]:29328639
[Au] Autor:Dubovina D; Mihailovic B; Bukumiric Z; Vlahovic Z; Miladinovic M; Mikovic N; Lazic Z
[Ti] Título:The use of hyaluronic and aminocaproic acid in the treatment of alveolar osteitis.
[So] Source:Vojnosanit Pregl;73(11):1010-5, 2016 Nov.
[Is] ISSN:0042-8450
[Cp] País de publicação:Serbia
[La] Idioma:eng
[Ab] Resumo:Background/Aim: Alveolar osteitis (AO), also known as "dry socket", is relatively common post-extraction complication. It probably occurs due to excessive fibrinolytic activity in the coagulum and is characterized by intense pain sensations. The aim of this clinical study was to examine the role of hyaluronic acid and aminocaproic acid in the treatment of AO. Methods: The study included 60 patients with the clinical diagnosis of AO. All the patients were divided into two groups of 30 patients each according to the applied non-pharmacological measure: irrigation ­ irrigation of dry socket with sterile saline; curettage ­ careful curettage. Both of these groups were further divided into three subgroups regarding the applied treatment (hyaluronic acid; hyaluronic acid + aminocaproic acid; Alvogyl ®, an anesthetic and antiseptic paste), each with 10 patients, according to the following protocol: 0.2 mL of hyaluronic acid in the form of a 0.8% gel; 2 mL of aminocaproic acid and hyaluronic acid; Alvogyl®. During each visit, scheduled for every two days until complete absence of painful sensations, the patients had the therapeutic method repeated as at the first examination. At each control visit the number of present symptoms and signs of AO was recorded, as well as the level of pain (measured with a visual analogue scale). Results: With the use of hyaluronic acid, with or without aminocaproic one, a statistically significantly faster reduction in pain sensations was achieved, along with the reduction in the number of symptoms and signs of AO compared to the use of Alvogyl®. Conclusion: Hyaluronic acid, applied alone or in combination with aminocaproic acid significantly reduces pain sensation, thus it can be successfully used in the treatment of AO.
[Mh] Termos MeSH primário: Ácido Aminocaproico/uso terapêutico
Analgésicos/uso terapêutico
Alvéolo Seco/tratamento farmacológico
Eugenol/uso terapêutico
Dor Facial/prevenção & controle
Ácido Hialurônico/uso terapêutico
Hidrocarbonetos Iodados/uso terapêutico
Óleos Voláteis/uso terapêutico
para-Aminobenzoatos/uso terapêutico
[Mh] Termos MeSH secundário: Adulto
Ácido Aminocaproico/efeitos adversos
Analgésicos/efeitos adversos
Curetagem/efeitos adversos
Combinação de Medicamentos
Alvéolo Seco/diagnóstico
Eugenol/efeitos adversos
Dor Facial/diagnóstico
Dor Facial/etiologia
Dor Facial/fisiopatologia
Feminino
Seres Humanos
Ácido Hialurônico/efeitos adversos
Hidrocarbonetos Iodados/efeitos adversos
Masculino
Meia-Idade
Óleos Voláteis/efeitos adversos
Medição da Dor
Percepção da Dor/efeitos dos fármacos
Limiar da Dor/efeitos dos fármacos
Estudos Prospectivos
Sérvia
Irrigação Terapêutica
Fatores de Tempo
Resultado do Tratamento
para-Aminobenzoatos/efeitos adversos
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (Analgesics); 0 (Drug Combinations); 0 (Hydrocarbons, Iodinated); 0 (Oils, Volatile); 0 (butyl aminobenzoate, eugenol, iodoform, spearmint oil drug combinations); 0 (para-Aminobenzoates); 3T8H1794QW (Eugenol); 9004-61-9 (Hyaluronic Acid); U6F3787206 (Aminocaproic Acid)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180213
[Lr] Data última revisão:
180213
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180113
[St] Status:MEDLINE
[do] DOI:10.2298/VSP150304125D


  5 / 5686 MEDLINE  
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[PMID]:28468191
[Au] Autor:Kim JH; Kim MB; Chang SW; Kang JW
[Ad] Endereço:Department of Otorhinolaryngology, Jeju National University School of Medicine, Jeju, South Korea.
[Ti] Título:Sialolithiasis of an Accessory Parotid Gland Causing Mid-Cheek Pain.
[So] Source:J Craniofac Surg;28(3):e216-e217, 2017 May.
[Is] ISSN:1536-3732
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:A 52-year-old woman presented with a slightly painful swelling of the right cheek area without postprandial aggravation of the symptom last 1 week. On physical examination, an approximately 1.5 cm sized firm, slightly tender mass was palpated on the right mid-cheek region, and she did not show any abnormal findings on neurologic examination. Computed tomography showed a well-enhanced lesion with low density of internal portion in right cheek area, and tiny calcification was noted within internal low-density portion of cheek mass. These findings suggested sialolithiasis of an accessory parotid gland with duct dilatation. Mid-cheek pain with conservative medical treatment was resolved and has not occurred during 1 year follow-up.
[Mh] Termos MeSH primário: Dor Facial/etiologia
Glândula Parótida/diagnóstico por imagem
Cálculos das Glândulas Salivares/complicações
[Mh] Termos MeSH secundário: Bochecha
Dor Facial/diagnóstico
Feminino
Seres Humanos
Meia-Idade
Cálculos das Glândulas Salivares/diagnóstico
Tomografia Computadorizada por Raios X
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180126
[Lr] Data última revisão:
180126
[Sb] Subgrupo de revista:D
[Da] Data de entrada para processamento:170505
[St] Status:MEDLINE
[do] DOI:10.1097/SCS.0000000000003400


  6 / 5686 MEDLINE  
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[PMID]:28741920
[Ti] Título:New Reliever of Jaw Pain Discovered.
[So] Source:J Calif Dent Assoc;44(9):543, 2016 Sep.
[Is] ISSN:1043-2256
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Analgésicos/uso terapêutico
Dor Facial/tratamento farmacológico
Arcada Osseodentária
Fenetilaminas/uso terapêutico
Canais de Cátion TRPV/antagonistas & inibidores
Tiazóis/uso terapêutico
[Mh] Termos MeSH secundário: Seres Humanos
[Pt] Tipo de publicação:NEWS
[Nm] Nome de substância:
0 (16-8 compound); 0 (Analgesics); 0 (Phenethylamines); 0 (TRPV Cation Channels); 0 (TRPV1 protein, human); 0 (Thiazoles)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180102
[Lr] Data última revisão:
180102
[Sb] Subgrupo de revista:D
[Da] Data de entrada para processamento:170726
[St] Status:MEDLINE


  7 / 5686 MEDLINE  
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[PMID]:29185308
[Au] Autor:Malcmacher L
[Ti] Título:The Occlusion Myth.
[So] Source:Dent Today;35(9):8, 10, 2016 Sep.
[Is] ISSN:8750-2186
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Oclusão Dentária
[Mh] Termos MeSH secundário: Bruxismo/diagnóstico
Bruxismo/etiologia
Bruxismo/terapia
Dor Facial/diagnóstico
Dor Facial/etiologia
Dor Facial/terapia
Seres Humanos
Má Oclusão/diagnóstico
Má Oclusão/terapia
Síndrome da Disfunção da Articulação Temporomandibular/diagnóstico
Síndrome da Disfunção da Articulação Temporomandibular/etiologia
Síndrome da Disfunção da Articulação Temporomandibular/terapia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171221
[Lr] Data última revisão:
171221
[Sb] Subgrupo de revista:D
[Da] Data de entrada para processamento:171201
[St] Status:MEDLINE


  8 / 5686 MEDLINE  
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[PMID]:28987152
[Au] Autor:Renton T
[Ti] Título:Current and Anticipated Developments in the Diagnosis and Management of Dental and Related Pain.
[So] Source:Prim Dent J;6(3 Suppl):38-43, 2017 Aug 31.
[Is] ISSN:2050-1684
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Dor Facial/diagnóstico
Dor Facial/etiologia
Dor Facial/prevenção & controle
Doenças da Boca/complicações
Doenças da Boca/diagnóstico
Doenças da Boca/prevenção & controle
[Mh] Termos MeSH secundário: Analgésicos/uso terapêutico
Anestesia Dentária/métodos
Diagnóstico Diferencial
Seres Humanos
Procedimentos Cirúrgicos Bucais/efeitos adversos
Dor Pós-Operatória/diagnóstico
Dor Pós-Operatória/prevenção & controle
Fatores de Risco
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Analgesics)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171113
[Lr] Data última revisão:
171113
[Sb] Subgrupo de revista:D
[Da] Data de entrada para processamento:171009
[St] Status:MEDLINE
[do] DOI:10.1308/205016817821930881


  9 / 5686 MEDLINE  
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[PMID]:28670951
[Au] Autor:Yeo NK; Park WJ; Ryu IS; Lim HW; Song YJ
[Ad] Endereço:1 Department of Otorhinolaryngology, Gangneung Asan Hospital, University of Ulsan College of Medicine, Gangneung, Republic of Korea.
[Ti] Título:Is Facial or Head Pain Related to the Location of Lesions on Computed Tomography in Chronic Rhinosinusitis?
[So] Source:Ann Otol Rhinol Laryngol;126(8):589-596, 2017 Aug.
[Is] ISSN:1943-572X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Facial or head pain is not an infrequent symptom among patients diagnosed with chronic rhinosinusitis (CRS), but few reports have investigated the pain in CRS, including the relationship between pain and sites of CRS. The aim of this study was to investigate whether pain is related to the location of lesions on computed tomography (CT) in CRS. METHODS: We analyzed 203 patients who underwent endoscopic sinus surgery (ESS) for 2 years. Patients were assessed using the questionnaires on pain, provided 1 day prior to the operation and 6 months post operation. Sites of CRS were evaluated using CT. We analyzed whether the degree of inflammation in each sinus had an effect on the location of pain. RESULTS: Seventy-eight patients (38.4%) had preoperative facial or head pain. There was no difference in the sinus inflammation scores in CT findings, based on the presence of pain. Pain was most commonly located in the periorbital area, followed by the frontal, vertex, occipital, and facial areas. No significant correlation was found between the sinuses and the location of pain. CONCLUSIONS: This study indicates that in CRS patients, several sites of pain are involved, particularly in the periorbital area; these sites were not found to be related to the location of CRS.
[Mh] Termos MeSH primário: Dor Facial/diagnóstico por imagem
Cefaleia/diagnóstico por imagem
Rinite/diagnóstico por imagem
Sinusite/diagnóstico por imagem
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Doença Crônica
Endoscopia
Feminino
Seres Humanos
Masculino
Meia-Idade
Procedimentos Cirúrgicos Otorrinolaringológicos
Medição da Dor
Rinite/cirurgia
Sinusite/cirurgia
Inquéritos e Questionários
Tomografia Computadorizada por Raios X
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170821
[Lr] Data última revisão:
170821
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170704
[St] Status:MEDLINE
[do] DOI:10.1177/0003489417717268


  10 / 5686 MEDLINE  
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[PMID]:28601424
[Au] Autor:Miest RY; Bruce AJ; Comfere NI; Hadjicharalambous E; Endly D; Lohse CM; Rogers RS
[Ad] Endereço:Department of Dermatology, Mayo Clinic, Rochester, MN.
[Ti] Título:A Diagnostic Approach to Recurrent Orofacial Swelling: A Retrospective Study of 104 Patients.
[So] Source:Mayo Clin Proc;92(7):1053-1060, 2017 Jul.
[Is] ISSN:1942-5546
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To identify patients evaluated in an outpatient setting at our institution with a presentation of recurrent orofacial swelling and to review the spectrum of causes to outline a diagnostic approach. PATIENTS AND METHODS: A retrospective study of 104 patients with more than 1 episode of orofacial swelling lasting for more than 5 days identified through a keyword search of the electronic health record from January 2, 2000, through July 5, 2011. RESULTS: Patients were categorized according to final cause of orofacial swelling: idiopathic orofacial granulomatosis, solid facial edema due to rosacea and acne vulgaris, Crohn disease, contact dermatitis, sarcoidosis, exfoliative cheilitis, lichen planus, actinic cheilitis, cheilitis glandularis, lymphedema, miscellaneous, and multifactorial. Granulomatous inflammation was noted on biopsy in 40 of 85 patients (47%). Oral involvement was associated with Crohn disease (P<.001), and facial and periorbital swelling was associated with solid facial edema in the setting of rosacea and acne vulgaris (P<.001). CONCLUSION: The broad range of diagnoses responsible for recurrent orofacial swelling underscores the diagnostic challenge and importance of a thorough multidisciplinary evaluation to identify underlying causes.
[Mh] Termos MeSH primário: Diagnóstico Diferencial
Dor Facial/diagnóstico
Granulomatose Orofacial/diagnóstico
Recidiva
[Mh] Termos MeSH secundário: Adulto
Biópsia/métodos
Doença de Crohn/diagnóstico
Face
Feminino
Seres Humanos
Lábio
Masculino
Estudos Retrospectivos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170731
[Lr] Data última revisão:
170731
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170612
[St] Status:MEDLINE



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