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[PMID]:29240487
[Au] Autor:Woodward S
[Ad] Endereço:Head of Clinical Education, Florence Nightingale Faculty of Nursing, King's College London.
[Ti] Título:Treating chronic constipation and faecal incontinence using transanal irrigation.
[So] Source:Br J Nurs;26(22):1220-1222, 2017 Dec 14.
[Is] ISSN:0966-0461
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Constipação Intestinal/enfermagem
Incontinência Fecal/enfermagem
Irrigação Terapêutica
[Mh] Termos MeSH secundário: Canal Anal
Seres Humanos
Irrigação Terapêutica/métodos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180306
[Lr] Data última revisão:
180306
[Sb] Subgrupo de revista:N
[Da] Data de entrada para processamento:171215
[St] Status:MEDLINE
[do] DOI:10.12968/bjon.2017.26.22.1220


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[PMID]:29353428
[Au] Autor:Regadas FSP; Regadas Filho FSP
[Ad] Endereço:School of Medicine, Federal University of Ceara, Fortaleza, Brazil.
[Ti] Título:Staplers for obstructed defecation syndrome.
[So] Source:Tech Coloproctol;22(1):1-3, 2018 01.
[Is] ISSN:1128-045X
[Cp] País de publicação:Italy
[La] Idioma:eng
[Mh] Termos MeSH primário: Constipação Intestinal
Defecação
[Mh] Termos MeSH secundário: Seres Humanos
Reto
Grampeadores Cirúrgicos
Resultado do Tratamento
[Pt] Tipo de publicação:EDITORIAL; COMMENT
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180226
[Lr] Data última revisão:
180226
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180122
[St] Status:MEDLINE
[do] DOI:10.1007/s10151-017-1743-4


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[PMID]:29378102
[Au] Autor:Pilipenko VI; Teplyuk DA; Shakhovskaya AK; Isakov VA; Vorobyova VM; Vorobyova IS; Glazkova IV; Kochetkova AA; Mikheeva GA; Yudina AV
[Ti] Título:[Dry jelly concentrate with vitamins and dietary fiber in patients with IBS with constipation: a comparative controlled study].
[So] Source:Vopr Pitan;84(6):83-91, 2015.
[Is] ISSN:0042-8833
[Cp] País de publicação:Russia (Federation)
[La] Idioma:rus
[Ab] Resumo:Irritable bowel syndrome (IBS) is highly prevalent functional gastrointestinal disorder associated with decrease in quality of life and a high social cost. Diet is one of several therapeutic options in IBS treatment; therefore the development and clinical evaluation of innovative functional food for IBS patients is useful. Dry jelly concentrate containing 3 g inulin, 10 mg curcumin and 1.8 mg of pyridoxine was developed and clinically evaluated. Fifty patients fulfilling the Rome III criteria for IBS-C were randomly assigned into two groups: one received standard diet plus two jelly drinks a day for 2 weeks and control group received standard diet. Response to therapy was recorded on a daily basis using Likert scale of abdominal pain, bloating and feeling of incomplete bowel emptying, frequency of bowel movement, Bristol stool scale, and quality of life assessed by IBSQoL questionnaire before and after the treatment. Intake of functional food product (jelly) containing inulin and curcumin is associated with a significant positive effect on the stool parameters (from 0.6±0.24 to 1.15±0.65 t/d in stool frequency, p=0.001, from 2.62±1.23 to 3.99±1.27, index Bristol scale, p=0.001), a reduce of the severity of abdominal pain (from 1.69±0.71 to 1.36±0.44 Likert scale points, p=0.001), bloating (from 2.03±0.89 to 1.55±0.81 points of Likert scale, p=0.02) and a sense of incomplete bowel emptying (from 2.25±0.98 to 1.68±0.92 points of Likert scale, p=0.001), as well as an increase in quality of life (from 64.5±13.5 to 81.2±9.1%, Ñ€=0.05). Patients in control group have improvement in abdominal pain (from 2.16±0.58 to 1.8±0.61 Likert scale points, p=0.05) and bloating (from 2.42±0.83 to 2.16±0.71 Likert scale points, p=0.05) only. During the treatment period no significant adverse events were found. These results indicate that jelly concentrate containing inulin, curcumin and pyridoxine improves abdominal pain score, Bristol scale index and quality of life in patients with IBS-C.
[Mh] Termos MeSH primário: Bebidas
Constipação Intestinal
Fibras na Dieta/administração & dosagem
Síndrome do Intestino Irritável
Vitaminas/administração & dosagem
[Mh] Termos MeSH secundário: Adulto
Idoso
Constipação Intestinal/dietoterapia
Constipação Intestinal/fisiopatologia
Curcumina/administração & dosagem
Feminino
Seres Humanos
Inulina/administração & dosagem
Síndrome do Intestino Irritável/dietoterapia
Síndrome do Intestino Irritável/fisiopatologia
Masculino
Meia-Idade
Piridoxina/administração & dosagem
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (Dietary Fiber); 0 (Vitamins); 9005-80-5 (Inulin); IT942ZTH98 (Curcumin); KV2JZ1BI6Z (Pyridoxine)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180216
[Lr] Data última revisão:
180216
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180130
[St] Status:MEDLINE


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[PMID]:28458356
[Au] Autor:Hayashi H; Suzuki A; Ohata K; Ishihara M; Kubota Y; Kobayashi R; Shibata Y; Nakamura H; Nakamura N; Kitagawa J; Tsurumi H; Shimizu M; Itoh Y
[Ad] Endereço:Department of Pharmacy, Gifu University Hospital.
[Ti] Título:Control of Constipation in Patients Receiving CHOP or CHOP-Like Chemotherapy Regimens for Non-Hodgkin's Lymphoma.
[So] Source:Biol Pharm Bull;40(5):698-702, 2017.
[Is] ISSN:1347-5215
[Cp] País de publicação:Japan
[La] Idioma:eng
[Ab] Resumo:Management of constipation in patients receiving cyclophosphamide, doxorubicin, vincristine and prednisolone (CHOP) or CHOP-like chemotherapy regimens is important for prevention of paralytic ileus. We reported earlier that the laxative action of magnesium oxide is reversed by the concomitant use of antacids in cancer patients receiving opioid analgesics. Here, we assessed the prevalence of prophylactic laxative medication for the control of constipation in patients receiving CHOP or CHOP-like regimens for non-Hodgkin's lymphoma. Data obtained from 211 eligible patients were retrospectively analyzed. Almost all patients (99%) received anti-ulcer agents such as proton pump inhibitors and H receptor antagonists for the prophylaxis of gastric disorders associated with prednisolone. Prophylactic laxatives were prescribed in 86 patients (40.8%), in which magnesium oxide was used most predominantly (88.4%). However, magnesium oxide at doses of ≦2000 mg/d was not effective for prevention of constipation, although the compound totally inhibited the incidence of constipation at doses higher than 2000 mg/d. Therefore, it is important to avoid negative drug interaction between magnesium oxide and antacids in patients receiving CHOP chemotherapy.
[Mh] Termos MeSH primário: Protocolos de Quimioterapia Combinada Antineoplásica/efeitos adversos
Constipação Intestinal/induzido quimicamente
Constipação Intestinal/prevenção & controle
Laxantes/uso terapêutico
Linfoma não Hodgkin/complicações
Linfoma não Hodgkin/tratamento farmacológico
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Idoso de 80 Anos ou mais
Antiácidos/uso terapêutico
Constipação Intestinal/epidemiologia
Ciclofosfamida/efeitos adversos
Doxorrubicina/efeitos adversos
Feminino
Seres Humanos
Incidência
Óxido de Magnésio/uso terapêutico
Masculino
Meia-Idade
Prednisona/efeitos adversos
Estudos Retrospectivos
Vincristina/efeitos adversos
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antacids); 0 (Laxatives); 3A3U0GI71G (Magnesium Oxide); 5J49Q6B70F (Vincristine); 80168379AG (Doxorubicin); 8N3DW7272P (Cyclophosphamide); VB0R961HZT (Prednisone)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180212
[Lr] Data última revisão:
180212
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170502
[St] Status:MEDLINE
[do] DOI:10.1248/bpb.b16-01001


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[PMID]:28467330
[Au] Autor:Maconi G
[Ad] Endereço:Gastroenterology Unit, Department of Biomedical and Clinical Sciences, L. Sacco University Hospital, Milan, Italy. giovanni.maconi@unimi.it.
[Ti] Título:Diagnosis of symptomatic uncomplicated diverticular disease and the role of Rifaximin in management.
[So] Source:Acta Biomed;88(1):25-32, 2017 Apr 28.
[Is] ISSN:0392-4203
[Cp] País de publicação:Italy
[La] Idioma:eng
[Ab] Resumo: Patients with diverticulosis who develop persistent abdominal pain, bloating and changes in bowel habits not associated with overt inflammation may have symptomatic uncomplicated diverticular disease (SUDD). The severity and frequency of SUDD symptoms may have an impact on daily activities and severely affect quality of life. Effective management of SUDD should follow a three part strategy: divert, tackle and maintain. Divert to make the correct diagnosis: several symptoms of SUDD are common to other conditions that require different therapeutic approaches. However, several key differences should be used to diagnose SUDD. Pain in SUDD is normally in the iliac fossa, persistent, often lasting more than 24 hrs, and is not relieved by bowel movement, as is often the case with irritable bowel syndrome. Another difference is in the timing: the prevalence of SUDD increases with age, and patients under the age of 40 years are less likely to have diverticula. It is useful to establish whether a patient has diverticulosis, especially if the patient is relatively young; lack of diverticula excludes SUDD. Cross-sectional imaging is indicated; however, recent archival image data or ultrasonography may be useful alternatives. Laboratory tests should be ordered to exclude overt inflammation. Once the diagnosis of SUDD is made, the patient should receive effective therapy to tackle the condition. This should include dietary fibre supplementation and cyclic treatment with rifaximin 400 mg twice daily for 7 days per month. Once symptom control is achieved, it should be maintained by continuing therapy for at least 12 months.
[Mh] Termos MeSH primário: Doenças Diverticulares/diagnóstico
Doenças Diverticulares/tratamento farmacológico
Fármacos Gastrointestinais/uso terapêutico
Rifamicinas/uso terapêutico
[Mh] Termos MeSH secundário: Dor Abdominal/tratamento farmacológico
Biomarcadores/análise
Proteína C-Reativa/análise
Ensaios Clínicos como Assunto
Constipação Intestinal/tratamento farmacológico
Diagnóstico por Imagem
Diarreia/tratamento farmacológico
Fármacos Gastrointestinais/farmacologia
Seres Humanos
Complexo Antígeno L1 Leucocitário/análise
Rifamicinas/farmacologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Biomarkers); 0 (Gastrointestinal Agents); 0 (Leukocyte L1 Antigen Complex); 0 (Rifamycins); 9007-41-4 (C-Reactive Protein); L36O5T016N (rifaximin)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180125
[Lr] Data última revisão:
180125
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170504
[St] Status:MEDLINE
[do] DOI:10.23750/abm.v88i1.6360


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[PMID]:28467916
[Au] Autor:Martínez-Martínez MI; Calabuig-Tolsá R; Cauli O
[Ad] Endereço:Department of Nursing, University of Valencia, Valencia, Spain.
[Ti] Título:The effect of probiotics as a treatment for constipation in elderly people: A systematic review.
[So] Source:Arch Gerontol Geriatr;71:142-149, 2017 Jul.
[Is] ISSN:1872-6976
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:PURPOSE: Treating constipation in elderly people remains a challenge; the administration of probiotics may be a valid therapy for this problem as an alternative to traditional drug-based treatments. The objective of this systematic review was to evaluate the efficiency of probiotics in treating constipation in elderly people. METHODS: Articles related to this topic and published, without any time limitations, in the Medline, Embase, Scopus, Lilacs, or Cochrane databases were systematically reviewed according to Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines. The primary search terms were 'constipation' and 'probiotics'. The main inclusion criteria were: 1) the article was original and the whole text was published in English or Spanish and 2) included the primary search terms in the title, summary, or body text; 3) the studies had to have included 60 or more participants defined as 'elderly' and 4) have specifically evaluated the effect of the administration of probiotics. RESULTS: Of the 475 articles consulted, 9 met the inclusion criteria. Among the selected studies, there were four randomised and placebo-controlled trials and the remaining five reports were observational. Overall, our analysis of the randomised and placebo-controlled trials suggests that administration of probiotics significantly improved constipation in elderly individuals by 10-40% compared to placebo controls in which no probiotic was administered. The strain of bacteria most commonly tested was Bifidobacterium longum. However, caution is needed when interpreting these reports because of the heterogeneity of the original study designs, populations, and the risk of bias. Therefore, further placebo-controlled trials are necessary to determine the most efficient strains, doses, and the optimal treatment duration.
[Mh] Termos MeSH primário: Constipação Intestinal/tratamento farmacológico
Probióticos/uso terapêutico
[Mh] Termos MeSH secundário: Idoso
Idoso de 80 Anos ou mais
Ensaios Clínicos Controlados como Assunto
Feminino
Seres Humanos
Masculino
Probióticos/efeitos adversos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180110
[Lr] Data última revisão:
180110
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170504
[St] Status:MEDLINE


  7 / 11664 MEDLINE  
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[PMID]:29253850
[Au] Autor:Li DY; Dai YK; Zhang YZ; Huang MX; Li RL; Ou-Yang J; Chen WJ; Hu L
[Ad] Endereço:Institute of Gastroenterology, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
[Ti] Título:Systematic review and meta-analysis of traditional Chinese medicine in the treatment of constipation-predominant irritable bowel syndrome.
[So] Source:PLoS One;12(12):e0189491, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:AIM: This meta-analysis analyzed the efficacy and safety of traditional Chinese medicine (TCM) for the treatment of irritable bowel syndrome with constipation (IBS-C). METHODS: We searched seven electronic databases for randomized controlled trials investigating the efficacy of TCM in the treatment of IBS-C. The search period was from inception to June 1, 2017. Eligible RCTs compared TCM with cisapride and mosapride. Article quality was evaluated with the Cochrane Risk Bias Tool in the Cochrane Handbook by two independent reviewers. Begg's test was performed to evaluate publication bias. Review Manager 5.3 and Stata 12.0 were used for analyses. RESULTS: Eleven eligible studies comprising a total of 906 participants were identified. In the primary outcome, TCM showed significant improvement in overall clinical efficacy compared with cisapride and mosapride (odds ratio [OR] = 4.00; 95% confidence interval [CI]: 2.74,5.84; P < 0.00001). In terms of secondary outcomes, TCM significantly alleviated abdominal pain (OR = 5.69; 95% CI: 2.35, 13.78; P = 0.0001), defecation frequency (OR = 4.38; 95% CI: 1.93, 9.93. P = 0.0004), and stool form (OR = 4.96; 95% CI: 2.11, 11.65; P = 0.0002) in the treatment group as compared to the control group. A lower recurrence rate was associated with TCM as compared to cisapride and mosapride (OR = 0.15; 95% CI: 0.08, 0.27; P < 0.00001). No adverse effects were observed during TCM treatment. CONCLUSIONS: TCM showed greater improvement in terms of clinical efficacy in the treatment of IBS-C than cisapride and mosapride, although it was not possible to draw a definitive conclusion due to the small sample size, high risk, and low quality of the studies. Large multi-center and long-term high-quality randomized control trials are needed.
[Mh] Termos MeSH primário: Constipação Intestinal/terapia
Síndrome do Intestino Irritável/terapia
Medicina Tradicional Chinesa
[Mh] Termos MeSH secundário: Benzamidas/administração & dosagem
Cisaprida/administração & dosagem
Seres Humanos
Morfolinas/administração & dosagem
Razão de Chances
Ensaios Clínicos Controlados Aleatórios como Assunto
[Pt] Tipo de publicação:JOURNAL ARTICLE; META-ANALYSIS; REVIEW
[Nm] Nome de substância:
0 (Benzamides); 0 (Morpholines); I8MFJ1C0BY (mosapride); UVL329170W (Cisapride)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180108
[Lr] Data última revisão:
180108
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171219
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0189491


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[PMID]:27778256
[Au] Autor:Youssef M; Emile SH; Thabet W; Elfeki HA; Magdy A; Omar W; Khafagy W; Farid M
[Ad] Endereço:General Surgery Department, Colorectal Surgery Unit, Mansoura Faculty of Medicine, Mansoura University Hospitals, El Gomhuoria Street, Mansoura City, Dakahlia Providence, Egypt.
[Ti] Título:Comparative Study Between Trans-perineal Repair With or Without Limited Internal Sphincterotomy in the Treatment of Type I Anterior Rectocele: a Randomized Controlled Trial.
[So] Source:J Gastrointest Surg;21(2):380-388, 2017 02.
[Is] ISSN:1873-4626
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND AND AIM: Two types of rectocele exist; type I is characterized by relatively high resting anal pressures, whereas type II has lower resting anal pressures with associated pelvic organ prolapse. We compared trans-perineal repair (TPR) of rectocele with or without limited internal sphincterotomy (LIS) in the treatment of type I anterior rectocele. PATIENTS AND INTERVENTIONS: Consecutive patients with anterior rectocele were evaluated for inclusion. Sixty-two female patients with type I anterior rectocele were randomized and equally allocated to receive TPR alone (group I) or TPR with LIS (group II). The primary outcome was the clinical improvement of constipation. Secondary outcomes were recurrence of rectocele, operative time, and postoperative complications including fecal incontinence (FI). RESULTS: Clinical improvement of constipation and patients' satisfaction were significantly higher in group II at 1 year of follow-up (93.3 versus 70 %). Constipation scores significantly decreased in both groups postoperatively with more reduction being observed in group II (11.1 ± 2.1 in group I versus 8 ± 1.97 in group II). Significant reduction in the resting anal pressure was noticed in group II. Recurrence was recorded in three (10 %) patients of group I and one patient of group II. No significant differences between the two groups regarding the operative time and hospital stay were noted. CONCLUSION: Adding LIS to TPR of type I rectocele achieved better clinical improvement than TPR alone. The only drawback of LIS was the development of a minor degree of FI, which was temporary in duration.
[Mh] Termos MeSH primário: Esfincterotomia Lateral Interna
Períneo/cirurgia
Retocele/cirurgia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Constipação Intestinal/etiologia
Constipação Intestinal/prevenção & controle
Incontinência Fecal/etiologia
Incontinência Fecal/prevenção & controle
Feminino
Seres Humanos
Tempo de Internação
Meia-Idade
Duração da Cirurgia
Satisfação do Paciente
Complicações Pós-Operatórias/prevenção & controle
Retocele/complicações
Recidiva
Resultado do Tratamento
Adulto Jovem
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Em] Mês de entrada:1712
[Cu] Atualização por classe:180102
[Lr] Data última revisão:
180102
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161026
[St] Status:MEDLINE
[do] DOI:10.1007/s11605-016-3299-4


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[PMID]:29226416
[Au] Autor:Saito YA; Camilleri M
[Ad] Endereço:Clinical Enteric Neuroscience Translational and Epidemiological Research (CENTER), Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
[Ti] Título:Editorial: patient assessment of constipation-symptoms (PAC-SYM) questionnaire has a minimal important difference.
[So] Source:Aliment Pharmacol Ther;47(1):138-139, 2018 01.
[Is] ISSN:1365-2036
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Constipação Intestinal
Inquéritos e Questionários
[Mh] Termos MeSH secundário: Seres Humanos
Qualidade de Vida
[Pt] Tipo de publicação:JOURNAL ARTICLE; COMMENT
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171220
[Lr] Data última revisão:
171220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171212
[St] Status:MEDLINE
[do] DOI:10.1111/apt.14389


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Registro de Ensaios Clínicos
Texto completo
[PMID]:27779312
[Au] Autor:Zerbib F; Siproudhis L; Lehur PA; Germain C; Mion F; Leroi AM; Coffin B; Le Sidaner A; Vitton V; Bouyssou-Cellier C; Chene G; CONSTIMOD study investigators
[Ad] Endereço:Department of Gastroenterology, Bordeaux University Hospital, and Université de Bordeaux and Institut National de la Santé et de la Recherche Médicale (INSERM) CIC 1401, Bordeaux, France.
[Ti] Título:Randomized clinical trial of sacral nerve stimulation for refractory constipation.
[So] Source:Br J Surg;104(3):205-213, 2017 Feb.
[Is] ISSN:1365-2168
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Open studies have reported favourable results for sacral nerve stimulation in the treatment of refractory constipation. Here, its efficacy was assessed in a double-blind crossover RCT. METHODS: Patients with at least two of the following criteria were included: fewer than three bowel movements per week; straining to evacuate on more than 25 per cent of attempts; or sensation of incomplete evacuation on more than 25 per cent of occasions. Response to therapy was defined as at least three bowel movements per week and/or more than 50 per cent improvement in symptoms. Responders to an initial 3-week peripheral nerve evaluation were offered permanent implantation of a pulse generator and were assigned randomly in a crossover design to two 8-week intervals of active or sham stimulation. At the end of the two trial periods, the patients received active stimulation until the final evaluation at 1 year. RESULTS: Thirty-six patients (34 women; mean(s.d.) age 45(14) years) underwent peripheral nerve evaluation. Twenty responded and received a permanent stimulator. A positive response was observed in 12 of 20 and 11 of 20 patients after active and sham stimulation periods respectively (P = 0·746). Pain related to the device occurred in five patients and wound infection or haematoma in three, leading to definitive removal of the pulse generator in two patients. At 1 year, 11 of the 20 patients with an implanted device continued to respond. Stimulation had no significant effect on colonic transit time. CONCLUSION: These results do not support the recommendation of permanent implantation of a pulse generator in patients with refractory constipation who initially responded to temporary nerve stimulation. Registration number: NCT01629303 (http://www.clinicaltrials.gov).
[Mh] Termos MeSH primário: Constipação Intestinal/terapia
Terapia por Estimulação Elétrica/métodos
Plexo Lombossacral
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Estudos Cross-Over
Método Duplo-Cego
Terapia por Estimulação Elétrica/instrumentação
Feminino
Seguimentos
Seres Humanos
Neuroestimuladores Implantáveis
Masculino
Meia-Idade
Resultado do Tratamento
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; MULTICENTER STUDY; RANDOMIZED CONTROLLED TRIAL
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171215
[Lr] Data última revisão:
171215
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:161026
[Cl] Clinical Trial:ClinicalTrial
[St] Status:MEDLINE
[do] DOI:10.1002/bjs.10326



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