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| [PMID]: | 27884550 |
| [Au] Autor: | Wolever TM; Chiasson JL; Josse RG; Leiter LA; Maheux P; Rabasa-Lhoret R; Rodger NW; Ryan EA |
| [Ad] Endereço: | Department of Nutritional Sciences, University of Toronto, Toronto, Ontario, Canada; Department of Medicine, St. Michael's Hospital, Toronto, Ontario, Canada. Electronic address: thomas.wolever@utoronto.ca. |
| [Ti] Título: | Effects of Changing the Amount and Source of Dietary Carbohydrates on Symptoms and Dietary Satisfaction Over a 1-Year Period in Subjects with Type 2 Diabetes: Canadian Trial of Carbohydrates in Diabetes (CCD). |
| [So] Source: | Can J Diabetes;41(2):164-176, 2017 Apr. | | [Is] ISSN: | 2352-3840 |
| [Cp] País de publicação: | Canada |
| [La] Idioma: | eng |
| [Ab] Resumo: | OBJECTIVES: To determine the long-term effects of changing the amount or source of dietary carbohydrate on quality of life (QOL), symptoms and dietary satisfaction in people with type 2 diabetes. METHODS: Subjects with diabetes treated by diet alone (n=162) were randomly assigned to high-carbohydrate/high-glycemic-index (HGI) diets; high-carbohydrate/low-glycemic-index (LGI) diets; or lower-carbohydrate/high-monounsaturated-fat (LC) diets for 1 year. We measured QOL at baseline and at study's end, and we measured symptoms and dietary satisfaction quarterly. RESULTS: The HGI, LGI and LC diets contained, respectively, 47±1, 52±1 and 40±1% energy carbohydrate; 30±1, 27±1 and 40±1% fat with GI 64±0.4, 55±0.4 and 59±0.4. Significantly more participants reported increased flatulence on LGI than on LC and HGI diets at 3 months (41%, 19%, 14%; p<0.05), but not at 12 months (29%, 17%, 17%; ns). Abdominal distension was more severe (46% vs. 14%, 19%; p<0.05), and headache less severe (8% vs. 22%, 23%; p<0.05) on LGI than on both other diets. Increased appetite was more severe on LC (33%) than on HGI diets (14%, p<0.05). Joint/limb pains were less severe on LGI (16%) than HGI (28%) diets. LC elicited more severe gloomy thoughts (23%) than LGI (4%; p<0.05) but greater dietary-satisfaction (70%; p<0.05) than LGI (40%) and HGI (48%) diets. For all diets, glycated hemoglobin (A1C) levels increased less in those who gained less weight, had less increased appetite and were more satisfied with the enjoyment obtained from eating. CONCLUSIONS: Each diet elicited increased severity of 1 or more symptoms than the other diets. Although overall dietary satisfaction was greater on the 40% carbohydrate diet than on the 50% carbohydrate diet, the LGI diet was no less satisfying than the HGI diet. Changes in appetite and dietary satisfaction may influence body weight and glycemic control, or vice-versa. |
| [Mh] Termos MeSH primário: |
Diabetes Mellitus Tipo 2/dietoterapia
Carboidratos da Dieta/farmacologia
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| [Mh] Termos MeSH secundário: |
Apetite
Peso Corporal
Dietoterapia/efeitos adversos
Dietoterapia/métodos
Feminino
Flatulência
Índice Glicêmico
Soluço
Seres Humanos
Masculino
Meia-Idade
Qualidade de Vida
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| [Pt] Tipo de publicação: | JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL |
[Nm] Nome de substância:
| 0 (Dietary Carbohydrates) |
| [Em] Mês de entrada: | 1705 |
| [Cu] Atualização por classe: | 170531 |
[Lr] Data última revisão:
| 170531 |
| [Sb] Subgrupo de revista: | IM |
| [Da] Data de entrada para processamento: | 161126 |
| [St] Status: | MEDLINE |
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