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[PMID]:29203743
[Au] Autor:Krekoten OM; Dereziuk AV; Ihnaschuk OV; Holovchanska SE
[Ad] Endereço:Department Of Public Health, National Pirogov Memorial Medical University, Vinnytsya, Ukraine.
[Ti] Título:Analysis of major risk factors affecting those working in the agrarian sector (based on a sociological survey).
[So] Source:Wiad Lek;70(5):925-929, 2017.
[Is] ISSN:0043-5147
[Cp] País de publicação:Poland
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: Issues related to labour potential, its state and problems have consistently been a focus of attention for the International Labour Organisation (ILO). Its respective analysis shows that labour potential problems remain unresolved in many countries of the world. According to the World Health Organisation (WHO), adverse working conditions are among major factors of occupational disease development in Europe and the reason for disabilities of economically active population during 2.5% of their lifetime. The aim of the present study is to identify and analyse major risk factors, which have a bearing on people working in agriculture in the course of exercising their occupation, with account of forms of ownership of agricultural enterprises. MATERIAL AND METHODS: Carried out was a cross-sectional study involving a sociological survey of 412 respondents - those working in agriculture - who made up the primary group and the control group. The study revealed 21 risk factors, 9 of which were work-related. A modified elementary cybernetic model of studying impact efficiency was developed with the view of carrying out a structural analysis of the sample group and choosing relevant methodological approaches. RESULTS: It has been established that harmful factors related to working environment and one's lifestyle are decisive in the agrarian sector, particularly for workers of privately owned businesses. For one out of three respondents harmful working conditions manifested themselves as industrial noise (31.7±3.4), vibration (29.0±2.1) trunk bending and constrained working posture (36.6±3.4). The vast majority of agricultural workers (91.6±2.5) admitted they could not afford proper rest during their annual leave; male respondents abused alcohol (70.6±3.0) and smoking (41.4±2.0 per 100 workers). CONCLUSION: The research established the structure of risk factors, which is sequentially represented by the following groups: behavioral (smoking, drinking of alcohol, rest during annual leave, physical culture), working environment and work activities (occupation, work experience, safety measures, working environment, organization and management), socioeconomic (education, financial situation).
[Mh] Termos MeSH primário: Doenças dos Trabalhadores Agrícolas/epidemiologia
Fazendeiros/estatística & dados numéricos
Nível de Saúde
Saúde do Trabalhador/estatística & dados numéricos
[Mh] Termos MeSH secundário: Adulto
Doenças dos Trabalhadores Agrícolas/psicologia
Estudos Transversais
Fazendeiros/psicologia
Feminino
Seres Humanos
Masculino
Meia-Idade
Fatores de Risco
Classe Social
Fatores Socioeconômicos
Ucrânia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171206
[St] Status:MEDLINE


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[PMID]:28742449
[Au] Autor:Harrington MJ; Lloyd K
[Ad] Endereço:a Department of Occupational and Environmental Health Sciences, Pacific Northwest Agricultural Safety and Health Center , University of Washington , Seattle , Washington , USA.
[Ti] Título:A Case History Introducing the Oregon Ag Seminar Series-Keys to Program and Research-to-Practice Success.
[So] Source:J Agromedicine;22(4):420-424, 2017.
[Is] ISSN:1545-0813
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:This case history of Oregon state's Ag Seminar Series is consistent with the Socio-Ecological Model, demonstrating how policy at a state level can influence an organizational approach with impacts that ultimately influence safety practices on the farm. From modest beginnings, the Ag Seminar Series, offered through a workers compensation insurance company, now serves over 2,300 Oregon farmers annually in English and Spanish. This case offers unique but also replicable methods for educators, insurers, and researchers in safety education, safety motivators, and research-to-practice (r2p).
[Mh] Termos MeSH primário: Acidentes de Trabalho/história
Doenças dos Trabalhadores Agrícolas/história
Agricultura/educação
Saúde do Trabalhador/educação
Saúde do Trabalhador/história
[Mh] Termos MeSH secundário: Acidentes de Trabalho/economia
Acidentes de Trabalho/prevenção & controle
Doenças dos Trabalhadores Agrícolas/economia
Doenças dos Trabalhadores Agrícolas/prevenção & controle
Agricultura/economia
Agricultura/recursos humanos
História do Século XX
História do Século XXI
Seres Humanos
Saúde do Trabalhador/economia
Saúde do Trabalhador/recursos humanos
Oregon
[Pt] Tipo de publicação:HISTORICAL ARTICLE; JOURNAL ARTICLE
[Em] Mês de entrada:1712
[Cu] Atualização por classe:180223
[Lr] Data última revisão:
180223
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170726
[St] Status:MEDLINE
[do] DOI:10.1080/1059924X.2017.1356777


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[PMID]:28453114
[Au] Autor:Leal-Bohórquez AF; Castro-Osorio CM; Wintaco-Martínez LM; Villalobos R; Puerto-Castro GM
[Ad] Endereço:Instituto Nacional de Salud. Bogotá. Colombia. andres_leal@yahoo.com; ccastro@ins.gov.co; mairawm@hotmail.com; gpuerto@ins.gov.co.
[Ti] Título:[Tuberculosis caused by Mycobacterium bovis in workers of bovine tuberculosis sanitation farms in Antioquia, Boyacá and Cundinamarca].
[Ti] Título:Tuberculosis por Mycobacterium bovis en trabajadores de fincas en saneamiento para tuberculosis bovina, de Antioquia, Boyacá y Cundinamarca..
[So] Source:Rev Salud Publica (Bogota);18(5):727-737, 2016 Sep-Oct.
[Is] ISSN:0124-0064
[Cp] País de publicação:Colombia
[La] Idioma:spa
[Ab] Resumo:Objective: To perform classic and molecular epidemiological surveillance of human tuberculosis caused by Mycobacterium bovis in bovine supply chains at farms with PPD positive bovines in the departments of Antioquia, Boyacá and Cundinamarca during a one-year period. Methods: Livestock farms with PPD positive bovines or buffalos were visited in the study departments according to information obtained in the "Programa Nacional de Tuberculosis bovina" (National program on bovine Tuberculosis) released by ICA (Colombian Agriculture and Livestock Institute). Data on socio-demographic information and tuberculosis risk factors associated to the occupation were collected through a survey applied to all workers at the visited farms. Sputum samples were obtained after informed consent. The sputa underwent microbiological and molecular testing to identify members of the M. tuberculosis complex. Results : Thirty-three livestock farms were visited and information of 164 workers from the bovine supply chain was collected. Staying in a PPD positive farm for more than a year, ignorance about the disease and the presence of possible vectors, like dogs and cats, were identified as possible risk factors for developing tuberculosis. No cases of tuberculosis caused by M. bovis or M. tuberculosis in workers of the visited farms were found. Conclusion : No cases of the disease caused by this zoonotic agent were documented in the departments of Antioquia, Boyacá and Cundinamarca.
[Mh] Termos MeSH primário: Doenças dos Trabalhadores Agrícolas/microbiologia
Criação de Animais Domésticos
Fazendas
Mycobacterium bovis
Tuberculose/microbiologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Idoso de 80 Anos ou mais
Doenças dos Trabalhadores Agrícolas/diagnóstico
Animais
Gatos
Bovinos
Colômbia
Vetores de Doenças
Cães
Escolaridade
Seres Humanos
Meia-Idade
Mycobacterium tuberculosis
Saneamento
Escarro/microbiologia
Tuberculose/diagnóstico
Tuberculose Bovina
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180216
[Lr] Data última revisão:
180216
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170429
[St] Status:MEDLINE


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[PMID]:28453066
[Au] Autor:Varona ME; Díaz SM; Briceño L; Sánchez-Infante CI; Torres CH; Palma RM; Groot H; Idrovo AJ
[Ad] Endereço:Universidad del Rosario, Bogotá, Colombia, leonardo.briceno@urosario.edu.co.
[Ti] Título:[Determining social factors related to pesticide poisoning among rice farmers in Colombia].
[Ti] Título:Determinantes sociales de la intoxicación por plaguicidas entre cultivadores de arroz en Colombia..
[So] Source:Rev Salud Publica (Bogota);18(4):617-629, 2016 Aug.
[Is] ISSN:0124-0064
[Cp] País de publicação:Colombia
[La] Idioma:spa
[Ab] Resumo:Objective Large quantities of pesticides are used in rice crops. The aim of this study is to characterize how farmers are exposed to pesticides and subsequent poisoning. Materials and Methods A multilevel (individual and community) multi-method study, which included ethnographic and survey methods, as well as measurement of pesticides in water and human samples, was performed. Results The production process is described and the main risk factors are presented. Pesticides are considered the greatest danger at work and at their homes. Workers have poor working conditions and are not protected by the system of occupational risks. Azinphos-methyl, endosulfan, ß-BHC, bromophos-methyl, bromophos-ethyl and 2,4- DDT were found in water samples. The survey included 381 workers with mild (12.86 %), moderate (67.98 %) and severe (5.51 %) poisonings respectively. Severe cases presented lower levels of education, lower levels of health care access to the contributory regimen of the Colombian social security system and higher incidence of cardiovascular disease, diabetes, herpes or other viral infections. Conclusion There are precarious working conditions that favor exposure to pesticides correlated to the exclusion of farmers from the occupational risk system, to poverty and to poor education. It is urgent to include these workers to the system of occupational risk system and to improve their living conditions, thus reducing unsafe practices when handling pesticides.
[Mh] Termos MeSH primário: Doenças dos Trabalhadores Agrícolas/induzido quimicamente
Produtos Agrícolas
Exposição Ocupacional/efeitos adversos
Oryza
Praguicidas/envenenamento
[Mh] Termos MeSH secundário: Agricultura
Colômbia
Fazendeiros
Seres Humanos
Praguicidas/análise
Praguicidas/sangue
Pesquisa Qualitativa
Fatores Socioeconômicos
Poluentes Químicos da Água/análise
Poluentes Químicos da Água/envenenamento
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Pesticides); 0 (Water Pollutants, Chemical)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180216
[Lr] Data última revisão:
180216
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170429
[St] Status:MEDLINE


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[PMID]:25815744
[Au] Autor:Kaewboonchoo O; Kongtip P; Woskie S
[Ad] Endereço:Department of Occupational Safety and Health, Faculty of Public Health, Mahidol University, Bangkok, Thailand orawan.kae@mahidol.ac.th.
[Ti] Título:Occupational health and safety for agricultural workers in Thailand: gaps and recommendations, with a focus on pesticide use.
[So] Source:New Solut;25(1):102-20, 2015 May.
[Is] ISSN:1541-3772
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Over 16.7 million workers in Thailand (42 percent of the working population) are engaged in agriculture, disproportionately from the lower socioeconomic strata of Thai society. Most agricultural workers (over 93 percent) work in the informal sector without the protections of regulations or enforcement of labor or health and safety laws or enrollment in a social security system. Although Thailand's use of herbicides, fungicides, and insecticides is growing, there is little regulation of the sale, use, or application of these potentially toxic chemicals. This paper summarizes the research to date on occupational health and safety for Thai agricultural workers, identifies gaps in pesticide regulations and the current systems for occupational health and safety and social support for Thai agricultural workers, and makes recommendations for future policy and research initiatives to fill the identified gaps.
[Mh] Termos MeSH primário: Doenças dos Trabalhadores Agrícolas/epidemiologia
Doenças dos Trabalhadores Agrícolas/prevenção & controle
Exposição Ocupacional/prevenção & controle
Praguicidas/efeitos adversos
Segurança
[Mh] Termos MeSH secundário: Acidentes de Trabalho/prevenção & controle
Acidentes de Trabalho/estatística & dados numéricos
Fazendeiros
Seres Humanos
Capacitação em Serviço/organização & administração
Saúde do Trabalhador
Traumatismos Ocupacionais/epidemiologia
Traumatismos Ocupacionais/prevenção & controle
Resíduos de Praguicidas
Roupa de Proteção
Assistência Pública/organização & administração
Apoio Social
Medicina Estatal/organização & administração
Tailândia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, U.S. GOV'T, P.H.S.
[Nm] Nome de substância:
0 (Pesticide Residues); 0 (Pesticides)
[Em] Mês de entrada:1601
[Cu] Atualização por classe:180216
[Lr] Data última revisão:
180216
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150328
[St] Status:MEDLINE
[do] DOI:10.1177/1048291115569028


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[PMID]:27779308
[Au] Autor:Flunker JC; Clouser JM; Mannino D; Swanberg J
[Ad] Endereço:Department of Epidemiology, College of Public Health, University of Kentucky, Lexington, Kentucky.
[Ti] Título:Pulmonary function among Latino thoroughbred horse farmworkers.
[So] Source:Am J Ind Med;60(1):35-44, 2017 Jan.
[Is] ISSN:1097-0274
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Latino thoroughbred workers may be at risk for developing abnormal pulmonary function related to occupational exposures. METHODS: Eighty worker participants were recruited via community-based purposive sampling. Questionnaires and spirometry tests were administered by trained lay health promoters. Demographic and occupational factors were assessed for associations with respiratory outcomes via multivariable logistic regression. RESULTS: Twenty-seven percent of participants exhibited abnormal pulmonary function (primarily restrictive), 79% reported any respiratory symptoms, and 94% infrequently used dust masks. Shorter duration of both current horse farm employment (≤5 years) and time living in the United States (≤10 years) increased the odds of abnormal pulmonary function. Shorter time living in the United States increased the odds of upper respiratory symptoms and shorter duration of current horse farm employment increased the odds of lower respiratory symptoms. CONCLUSIONS: Abnormal pulmonary function was high among this vulnerable worker group, suggesting the need for increased dust mask usage and further exposure assessment. Am. J. Ind. Med. 60:35-44, 2017. © 2016 Wiley Periodicals, Inc.
[Mh] Termos MeSH primário: Doenças dos Trabalhadores Agrícolas/epidemiologia
Poluição do Ar em Ambientes Fechados/efeitos adversos
Criação de Animais Domésticos
Hispano-Americanos
Exposição por Inalação/efeitos adversos
Doenças Respiratórias/epidemiologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Doenças dos Trabalhadores Agrícolas/etiologia
Doenças dos Trabalhadores Agrícolas/fisiopatologia
Animais
Tosse/epidemiologia
Tosse/etiologia
Estudos Transversais
Poeira
Dispneia/epidemiologia
Dispneia/etiologia
Feminino
Volume Expiratório Forçado
Inquéritos Epidemiológicos
Cavalos
Seres Humanos
Kentucky/epidemiologia
Pulmão/fisiopatologia
Masculino
Meia-Idade
Projetos Piloto
Sons Respiratórios/etiologia
Doenças Respiratórias/etiologia
Doenças Respiratórias/fisiopatologia
Autorrelato
Espirometria
Capacidade Vital
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Dust)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180109
[Lr] Data última revisão:
180109
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161026
[St] Status:MEDLINE
[do] DOI:10.1002/ajim.22667


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[PMID]:29284253
[Au] Autor:Spiewak R; Góra-Florek A; Horoch A; Jarosz MJ; Dorynska A; Golec M; Dutkiewicz J
[Ad] Endereço:Department of Experimental Dermatology and Cosmetology, Jagiellonian University Medical College, Krakow, Poland. spiewak.eu@gmail.com.
[Ti] Título:Risk factors for work-related eczema and urticaria among vocational students of agriculture.
[So] Source:Ann Agric Environ Med;24(4):716-721, 2017 Dec 23.
[Is] ISSN:1898-2263
[Cp] País de publicação:Poland
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION AND OBJECTIVE: Farmers are at high risk of occupational skin diseases which may start already during vocational training. This study was aimed at identification of risk factors for work-related skin diseases among vocational students of agriculture. MATERIAL AND METHODS: The study involved 440 students (245 males, 195 females aged 17-21 years) in 11 vocational schools which were at least 100 km from each other. The protocol included a physician-managed questionnaire and medical examination, skin prick tests, patch tests, total IgE and Phadiatop. Logistic regression model was used for the identification of relevant risk factors. RESULTS: Work-related dermatoses were diagnosed in 29 study participants (6.6%, 95%CI: 4.3-8.9%): eczema in 22, urticaria in 14, and co-existence of both in 7 students. Significant risk factors for work-related eczema were: history of respiratory allergy (OR=10.10; p<0.001), history of eczema (itchy rash) provoked by wet work and detergents before entering the school (OR=5.85; p<0.001), as well as history of contact dermatitis to metals, rubber or cosmetics prior to inscription (OR=2.84; p=0.016), and family history of any skin disease (OR=2.99; p=0.013). Significant risk factors for work-related urticaria were: history of allergic rhinitis and asthma prior to inscription (OR=7.29; p=0.006), positive skin prick tests to work place allergens (OR=4.65; p=0.002) and to environmental allergens (OR=3.79; p=0.009), and positive Phadiatop test (OR=3.61; p=0.013). CONCLUSIONS: Work-related skin diseases are common among vocational students of agriculture. Atopy, past history of asthma, allergic rhinitis, and eczema (either atopic, allergic or irritant) are relevant risk factors for work-related eczema and urticaria in young farmers, along with family history of any skin disease. Positive skin prick tests seem relevant, especially in the case of urticaria. Asking simple, aimed questions during health checks while enrolling students into agricultural schools would suffice to identify students at risk for work-related eczema and urticaria, giving them the chance for selecting a safer profession, and hopefully avoiding an occupational disease in the future.
[Mh] Termos MeSH primário: Doenças dos Trabalhadores Agrícolas/epidemiologia
Eczema/epidemiologia
Urticária/epidemiologia
[Mh] Termos MeSH secundário: Adolescente
Doenças dos Trabalhadores Agrícolas/diagnóstico
Agricultura
Eczema/diagnóstico
Fazendeiros/estatística & dados numéricos
Feminino
Seres Humanos
Masculino
Fatores de Risco
Testes Cutâneos
Estudantes/estatística & dados numéricos
Urticária/diagnóstico
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180105
[Lr] Data última revisão:
180105
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171230
[St] Status:MEDLINE


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[PMID]:29236884
[Au] Autor:Costa PFFD; Santos SLD; Silva MSD; Gurgel IGD
[Ad] Endereço:Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Programa de Pós-Graduação em Saúde Pública. Recife, PE, Brasil.
[Ti] Título:Prevalence of common mental disorders among sugarcane workers.
[So] Source:Rev Saude Publica;51:113, 2017 Dec 11.
[Is] ISSN:1518-8787
[Cp] País de publicação:Brazil
[La] Idioma:eng; por
[Ab] Resumo:OBJECTIVE: To estimate the prevalence of common mental disorders and to analyze the associated factors in migrant and sugarcane workers. METHODS: This is a cross-sectional study carried out with 110 workers. Common mental disorders were evaluated using the Self-Reporting Questionnaire (SRQ-20), and sociodemographic, occupational, and lifestyle variables were studied. The CAGE questionnaire was used to detect the abuse of alcoholic beverages. RESULTS: The prevalence of common mental disorders affected 40% of the workers and the association showed statistical significance for the positive result of the CAGE test, sickness, absence from work, and medical care during the harvest period. CONCLUSIONS: The suspected cases of problem drinkers and the control mechanisms used by the mill for workers who miss work or become ill are factors that can cause common mental disorders.
[Mh] Termos MeSH primário: Doenças dos Trabalhadores Agrícolas/epidemiologia
Transtornos Mentais/epidemiologia
Migrantes/estatística & dados numéricos
[Mh] Termos MeSH secundário: Adulto
Doenças dos Trabalhadores Agrícolas/psicologia
Brasil/epidemiologia
Estudos Transversais
Seres Humanos
Estilo de Vida
Masculino
Meia-Idade
Prevalência
Fatores de Risco
Inquéritos e Questionários
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171220
[Lr] Data última revisão:
171220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171214
[St] Status:MEDLINE


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[PMID]:29182467
[Au] Autor:Tsai SS; Weng YH; Chiu YW; Yang CY
[Ad] Endereço:a Department of Healthcare Administration , I-Shou University , Kaohsiung , Taiwan.
[Ti] Título:Farming and mortality rates attributed to non-Hodgkin's lymphoma in Taiwan.
[So] Source:J Toxicol Environ Health A;81(1-3):31-36, 2018.
[Is] ISSN:1528-7394
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Previous studies suggested an elevated risk of non-Hodgkin's lymphoma (NHL) among farmers. To date, no apparent study examined the association between farming and NHL in Asian countries. The aim of this study was to investigate whether farmers in Taiwan exhibited an increased risk of mortality attributed to NHL. To this end, a mortality odds ratio (MOR) study was conducted to estimate the relative risk of mortality attributed to NHL for farmers in Taiwan. Data on the decedents enrolled in this investigation were derived from the death certificate database for the period 1997-2009. The study group comprised individuals who died from NHL and who were 50 years or older. The control group consisted of subjects who died from all other causes, excluding cancers, in the corresponding age group. Multiple logistic regression analysis was performed to compute the MOR, with adjustments for gender, age at death, year of death, marital status, and urbanizational levels. Among 32,456 deceased farmers, 205 died due to NHL. Farmers were found to have a nonsignificantly higher MOR than nonfarmers. This risk estimate is similar to estimates in previous meta-analyses. The MOR for NHL was higher among farmers who died 65 years or older than among those who died at younger ages. The findings indicate that farming in Taiwan may increase the risk of death attributed to NHL. Exposure to pesticides might be an influential factor contributing to high risk of mortality attributed to NHL among farmers and therefore needs to be further investigated.
[Mh] Termos MeSH primário: Doenças dos Trabalhadores Agrícolas/mortalidade
Linfoma não Hodgkin/mortalidade
[Mh] Termos MeSH secundário: Idoso
Atestado de Óbito
Demografia
Feminino
Seres Humanos
Masculino
Meia-Idade
Fatores de Risco
Taiwan/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171215
[Lr] Data última revisão:
171215
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171129
[St] Status:MEDLINE
[do] DOI:10.1080/15287394.2017.1408362


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[PMID]:28954095
[Au] Autor:Purim KSM; Peretti MC; Fillus J; Olandoski M
[Ad] Endereço:Discipline of Dermatology of the Medical School - Universidade Positivo (UP) - Curitiba (PR), Brazil.
[Ti] Título:Chromoblastomycosis: tissue modifications during itraconazole treatment.
[So] Source:An Bras Dermatol;92(4):478-483, 2017 Jul-Aug.
[Is] ISSN:1806-4841
[Cp] País de publicação:Brazil
[La] Idioma:eng
[Ab] Resumo:Background:: Histological and mycological changes during itraconazole use have not been totally established in chromoblastomycosis. Objectives:: To evaluate tissue modifications in chromoblastomycosis carriers under itraconazole treatment. Methods:: A histological retrospective study of 20 cases of chromoblastomycosis seen at the university hospital at the south of Brazil, during itraconazole 400 mg daily treatment. Patients were classified into two groups: plaque or tumor lesions, and underwent periodic evaluations every four months during three years. Hematoxylin-eosin stain was used to analyze epidermal modifications, inflammatory infiltrate and fibrosis, and Fontana-Masson stain for parasite evaluation. Results:: Fontana-Masson stain was superior to hematoxylin-eosin stain in fungal count in the epidermis (mean difference=0.14; p<0.05). The most distinct mycosis tissue responses were registered in the dermis. Epidermal thinning, granulomatous infiltrate decrease or disappearance, fibrosis increase and quantitative/morphological changes occurred during treatment. Study limitations:: Patients could not be located to have their current skin condition examined. Conclusion:: Parasitic and tissue changes verified in this study can reflect the parasite-host dynamics under itraconazole action.
[Mh] Termos MeSH primário: Doenças dos Trabalhadores Agrícolas/tratamento farmacológico
Doenças dos Trabalhadores Agrícolas/microbiologia
Antifúngicos/uso terapêutico
Cromoblastomicose/tratamento farmacológico
Itraconazol/uso terapêutico
Pele/patologia
[Mh] Termos MeSH secundário: Adulto
Idoso
Idoso de 80 Anos ou mais
Doenças dos Trabalhadores Agrícolas/patologia
Biópsia
Cromoblastomicose/microbiologia
Cromoblastomicose/patologia
Feminino
Fungos/fisiologia
Interações Hospedeiro-Parasita/fisiologia
Seres Humanos
Masculino
Meia-Idade
Estudos Retrospectivos
Nitrato de Prata
Pele/microbiologia
Tela Subcutânea
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antifungal Agents); 0 (Fontana-Masson stain); 304NUG5GF4 (Itraconazole); 95IT3W8JZE (Silver Nitrate)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171010
[Lr] Data última revisão:
171010
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170928
[St] Status:MEDLINE



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