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Teixeira, Manoel Jacobsen
Texto completo SciELO Brasil
[PMID]:28562767
[Au] Autor:Medeiros CR; Brioschi ML; Souza SN; Teixeira MJ
[Ad] Endereço:Hospital Vital Brazil, Instituto Butantan, São Paulo, SP, Brasil.
[Ti] Título:Infrared thermography to diagnose and manage venomous animal bites and stings.
[So] Source:Rev Soc Bras Med Trop;50(2):260-264, 2017 Mar-Apr.
[Is] ISSN:1678-9849
[Cp] País de publicação:Brazil
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: Infrared imaging (IR) is a noninvasive technique that quantifies body surface temperature, producing a digital color image. IR has been used to study diseases in which skin temperature can reflect the presence of inflammation. METHODS: This was an observational pilot study of eight patients envenomed by snakes, spiders, and scorpions. All patients were examined using a thermal camera. RESULTS: In all cases, we obtained infrared images that corroborated clinical findings indicating localized effects of venom, specifically inflammation. CONCLUSIONS: IR has potential for use as a research, diagnostic, and monitoring tool for localized effects of animal venoms.
[Mh] Termos MeSH primário: Picadas de Escorpião/diagnóstico
Mordeduras de Serpentes/diagnóstico
Picaduras de Aranhas/diagnóstico
Termografia/métodos
[Mh] Termos MeSH secundário: Adulto
Feminino
Seres Humanos
Masculino
Projetos Piloto
Picadas de Escorpião/complicações
Mordeduras de Serpentes/complicações
Picaduras de Aranhas/complicações
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; OBSERVATIONAL STUDY
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170705
[Lr] Data última revisão:
170705
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170601
[St] Status:MEDLINE


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[PMID]:28422977
[Au] Autor:Robinson JR; Kennedy VE; Doss Y; Bastarache L; Denny J; Warner JL
[Ad] Endereço:Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, United States of America.
[Ti] Título:Defining the complex phenotype of severe systemic loxoscelism using a large electronic health record cohort.
[So] Source:PLoS One;12(4):e0174941, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: Systemic loxoscelism is a rare illness resulting from the bite of the recluse spider and, in its most severe form, can lead to widespread hemolysis, coagulopathy, and death. We aim to describe the clinical features and outcomes of the largest known cohort of individuals with moderate to severe loxoscelism. METHODS: We performed a retrospective, cross sectional study from January 1, 1995, to December 31, 2015, at a tertiary-care academic medical center, to determine individuals with clinical records consistent with moderate to severe loxoscelism. Age-, sex-, and race-matched controls were compared. Demographics, clinical characteristics, laboratory measures, and outcomes of individuals with loxoscelism are described. Case and control groups were compared with descriptive statistics and phenome-wide association study (PheWAS). RESULTS: During the time period, 57 individuals were identified as having moderate to severe loxoscelism. Of these, only 33% had an antecedent spider bite documented. Median age of individuals diagnosed with moderate to severe loxoscelism was 14 years old (IQR 9.0-24.0 years). PheWAS confirmed associations of systemic loxoscelism with 29 other phenotypes, e.g., rash, hemolytic anemia, and sepsis. Hemoglobin level dropped an average of 3.1 g/dL over an average of 2.0 days (IQR 2.0-6.0). Lactate dehydrogenase and total bilirubin levels were on average over two times their upper limit of normal values. Eighteen individuals of 32 tested had a positive direct antiglobulin (Coombs') test. Mortality was 3.5% (2/57 individuals). CONCLUSION: Systemic loxoscelism is a rare but devastating process with only a minority of patients recalling the toxic exposure; hemolysis reaches a peak at 2 days after admission, with some cases taking more than a week before recovery. In endemic areas, suspicion for systemic loxoscelism should be high in individuals, especially children and younger adults, presenting with a cutaneous ulcer and hemolysis or coagulopathy, even in the absence of a bite exposure history.
[Mh] Termos MeSH primário: Aranha Marrom Reclusa/patogenicidade
Coagulação Intravascular Disseminada/diagnóstico
Picaduras de Aranhas/diagnóstico
Venenos de Aranha/toxicidade
[Mh] Termos MeSH secundário: Adolescente
Animais
Bilirrubina/sangue
Estudos de Casos e Controles
Criança
Estudos Transversais
Coagulação Intravascular Disseminada/sangue
Coagulação Intravascular Disseminada/mortalidade
Coagulação Intravascular Disseminada/fisiopatologia
Registros Eletrônicos de Saúde/estatística & dados numéricos
Feminino
Hemoglobinas/metabolismo
Hemólise/efeitos dos fármacos
Seres Humanos
L-Lactato Desidrogenase/sangue
Masculino
Fenótipo
Estudos Retrospectivos
Picaduras de Aranhas/sangue
Picaduras de Aranhas/mortalidade
Picaduras de Aranhas/fisiopatologia
Análise de Sobrevida
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Hemoglobins); 0 (Spider Venoms); EC 1.1.1.27 (L-Lactate Dehydrogenase); RFM9X3LJ49 (Bilirubin)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:171019
[Lr] Data última revisão:
171019
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170420
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0174941


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[PMID]:28324071
[Au] Autor:Vangipuram R; Tong Y; Tyring SK
[Ad] Endereço:Center for Clinical Studies, Webster, Texas.
[Ti] Título:A Tender Rash on the Hand.
[So] Source:JAMA;317(11):1169-1170, 2017 Mar 21.
[Is] ISSN:1538-3598
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Exantema/diagnóstico
Dermatoses da Mão/diagnóstico
Herpes Simples/diagnóstico
Dermatopatias Vesiculobolhosas/diagnóstico
[Mh] Termos MeSH secundário: Aciclovir/análogos & derivados
Aciclovir/uso terapêutico
Adulto
Antivirais/uso terapêutico
Diagnóstico Diferencial
Dermatoses da Mão/tratamento farmacológico
Herpes Simples/tratamento farmacológico
Seres Humanos
Masculino
Dermatopatias Vesiculobolhosas/tratamento farmacológico
Picaduras de Aranhas/diagnóstico
Polegar
Valina/análogos & derivados
Valina/uso terapêutico
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antiviral Agents); HG18B9YRS7 (Valine); MZ1IW7Q79D (valacyclovir); X4HES1O11F (Acyclovir)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170327
[Lr] Data última revisão:
170327
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170322
[St] Status:MEDLINE
[do] DOI:10.1001/jama.2017.0224


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[PMID]:27563734
[Au] Autor:Chaves-Moreira D; de Moraes FR; Caruso ÍP; Chaim OM; Senff-Ribeiro A; Ullah A; da Silva LS; Chahine J; Arni RK; Veiga SS
[Ad] Endereço:Department of Cell Biology, Federal University of Paraná (UFPR), Curitiba, PR, Brazil.
[Ti] Título:Potential Implications for Designing Drugs Against the Brown Spider Venom Phospholipase-D.
[So] Source:J Cell Biochem;118(4):726-738, 2017 Apr.
[Is] ISSN:1097-4644
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Loxoscelism refers to the clinical symptoms that develop after brown spider bites. Brown spider venoms contain several phospholipase-D isoforms, which are the main toxins responsible for both the cutaneous and systemic effects of loxoscelism. Understanding of the phospholipase-D catalytic mechanism is crucial for the development of specific treatment that could reverse the toxic effects caused by the spider bite. Based on enzymatic, biological, structural, and thermodynamic tests, we show some features suitable for designing drugs against loxoscelism. Firstly, through molecular docking and molecular dynamics predictions, we found three different molecules (Suramin, Vu0155056, and Vu0359595) that were able to bind the enzyme's catalytic site and interact with catalytically important residues (His12 or His47) and with the Mg co-factor. The binding promoted a decrease in the recombinant brown spider venom phospholipase-D (LiRecDT1) enzymatic activity. Furthermore, the presence of the inhibitors reduced the hemolytic, dermonecrotic, and inflammatory activities of the venom toxin in biological assays. Altogether, these results indicate the mode of action of three different LiRecDT1 inhibitors, which were able to prevent the venom toxic effects. This strengthen the idea of the importance of designing a specific drug to treat the serious clinical symptoms caused by the brown spider bite, a public health problem in several parts of the world, and until now without specific treatment. J. Cell. Biochem. 118: 726-738, 2017. © 2016 Wiley Periodicals, Inc.
[Mh] Termos MeSH primário: Proteínas de Artrópodes/antagonistas & inibidores
Aranha Marrom Reclusa/enzimologia
Desenho de Drogas
Fosfolipase D/antagonistas & inibidores
Venenos de Aranha/antagonistas & inibidores
[Mh] Termos MeSH secundário: Animais
Proteínas de Artrópodes/química
Proteínas de Artrópodes/genética
Benzimidazóis/farmacologia
Aranha Marrom Reclusa/genética
Aranha Marrom Reclusa/patogenicidade
Avaliação Pré-Clínica de Medicamentos
Inibidores Enzimáticos/química
Inibidores Enzimáticos/farmacologia
Hemólise/efeitos dos fármacos
Seres Humanos
Cinética
Ligantes
Simulação de Acoplamento Molecular
Simulação de Dinâmica Molecular
Necrose
Fosfolipase D/química
Fosfolipase D/genética
Diester Fosfórico Hidrolases/química
Diester Fosfórico Hidrolases/genética
Piperidinas/farmacologia
Coelhos
Proteínas Recombinantes/genética
Pele/efeitos dos fármacos
Pele/patologia
Picaduras de Aranhas/tratamento farmacológico
Picaduras de Aranhas/enzimologia
Venenos de Aranha/química
Venenos de Aranha/genética
Suramina/farmacologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Arthropod Proteins); 0 (Benzimidazoles); 0 (Enzyme Inhibitors); 0 (Ligands); 0 (N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo(d)imidazol-1-yl)piperidin-1-yl)ethyl)-2-naphthamide); 0 (Piperidines); 0 (Recombinant Proteins); 0 (Spider Venoms); 0 (dermonecrotic toxin, Loxosceles intermedia); 0 (loxosceles venom); 6032D45BEM (Suramin); EC 3.1.4.- (Phosphoric Diester Hydrolases); EC 3.1.4.4 (Phospholipase D)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171103
[Lr] Data última revisão:
171103
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160827
[St] Status:MEDLINE
[do] DOI:10.1002/jcb.25678


  5 / 1079 MEDLINE  
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Texto completo SciELO Chile
[PMID]:28146203
[Au] Autor:Pichardo-Rodríguez R; Grandez-Urbina JA
[Ad] Endereço:Universidad Ricardo Palma, Lima, Perú.
[Ti] Título:[Loxoscelism and changes in coagulation profile].
[Ti] Título:Loxoscelismo y cambios en el perfil de coagulación..
[So] Source:Rev Chilena Infectol;33(6):712, 2016 Dec.
[Is] ISSN:0717-6341
[Cp] País de publicação:Chile
[La] Idioma:spa
[Mh] Termos MeSH primário: Transtornos da Coagulação Sanguínea/etiologia
Diester Fosfórico Hidrolases/envenenamento
Picaduras de Aranhas/complicações
Venenos de Aranha/envenenamento
[Mh] Termos MeSH secundário: Animais
Seres Humanos
Fatores de Tempo
[Pt] Tipo de publicação:LETTER
[Nm] Nome de substância:
0 (Spider Venoms); 0 (loxosceles venom); EC 3.1.4.- (Phosphoric Diester Hydrolases)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170202
[St] Status:MEDLINE


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Texto completo SciELO Brasil
[PMID]:28001231
[Au] Autor:Evangelista GF; Azevedo CS
[Ad] Endereço:Departamento de Biodiversidade, Evolução e Meio Ambiente, Instituto de Ciências Exatas e Biológicas, Universidade Federal de Ouro Preto, Ouro Preto, Minas Gerais, Brazil.
[Ti] Título:Arachnidism, scorpionism and ophidism in Ouro Preto Municipality, Minas Gerais State, Brazil.
[So] Source:Rev Soc Bras Med Trop;49(6):786-789, 2016 Nov-Dec.
[Is] ISSN:1678-9849
[Cp] País de publicação:Brazil
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: This retrospective study shows the profile of arachnidism, ophidism, and scorpionism in the Ouro Preto Municipality, Brazil, from January 2007 to December 2013. METHODS: The data were gathered from forms of the Epidemiological Surveillance Sector of the town's Health's Municipal Secretary. RESULTS: Of the 412 envenomations, 308 were caused by spiders, 78 by scorpions, and 26 by snakes. The highest number of incidents involved people aged 20-34 years. Females were more affected than males. There were no reports of death. CONCLUSIONS: The results show that envenomations caused by spiders, scorpions and snakes have decreased in recent years.
[Mh] Termos MeSH primário: Picadas de Escorpião/epidemiologia
Mordeduras de Serpentes/epidemiologia
Picaduras de Aranhas/epidemiologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Idoso de 80 Anos ou mais
Animais
Brasil/epidemiologia
Feminino
Seres Humanos
Incidência
Masculino
Meia-Idade
Estudos Retrospectivos
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1704
[Cu] Atualização por classe:171011
[Lr] Data última revisão:
171011
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161222
[St] Status:MEDLINE


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[PMID]:27886057
[Au] Autor:Soares ES; Stávale LM; Mendonça MC; Coope A; Cruz-Höfling MA
[Ad] Endereço:Department of Biochemistry and Tissue Biology, Institute of Biology, State University of Campinas, Campinas, SP 13083-863, Brazil. esiqueirasoares@gmail.com.
[Ti] Título:Age-Related Modulations of AQP4 and Caveolin-1 in the Hippocampus Predispose the Toxic Effect of Phoneutria nigriventer Spider Venom.
[So] Source:Int J Mol Sci;17(11), 2016 Nov 23.
[Is] ISSN:1422-0067
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:We have previously demonstrated that venom (PNV) causes blood-brain barrier (BBB) breakdown, swelling of astrocytes end-feet and fluid permeation into brain interstitium in rats. Caveolae and water channels respond to BBB alterations by co-participation in shear stress response and edema formation/resolution. Herein, we showed post-natal developmental-related changes of two BBB-associated transporter proteins: the endothelial caveolin-1 (Cav-1), the major scaffolding protein from caveolae frame, and the astroglial aquaporin-4 (AQP4), the main water channel protein expressed in astrocytic peri-vascular end-feet processes, in the hippocampus of rats intraperitoneally-administered PNV. Western blotting protein levels; immunohistochemistry (IHC) protein distribution in CA1, CA2, and CA3 subfields; and gene expression by Real Time-Polymerase Chain Reaction (qPCR) were assessed in post-natal Day 14 (P14) and 8-10-week-old rats over critical periods of envenomation. The intensity and duration of the toxic manifestations indicate P14 neonate rats more vulnerable to PNV than adults. Histologically, the capillaries of P14 and 8-10-week-old rats treated with PNV showed perivascular edema, while controls did not. The intensity of the toxic manifestations in P14 decreases temporally (2 > 5 > 24 h), while inversely the expression of AQP4 and Cav-1 peaked at 24 h when clinically PNV-treated animals do not differ from saline controls. IHC of AQP4 revealed that hippocampal CA1 showed the least expression at 2 h when toxic manifestation was maximal. Subfield IHC quantification revealed that in P14 rats Cav-1 peaked at 24 h when toxic manifestations were absent, whereas in 8-10-week-old rats Cav-1 peaked at 2 h when toxic signs were highest, and progressively attenuated such increases until 24 h, remaining though significantly above baseline. Considering astrocyte-endothelial physical and functional interactions, we hypothesize that age-related modulations of AQP4 and Cav-1 might be linked both to changes in functional properties of astrocytes during post-natal development and in the BBB breakdown induced by the venom of .
[Mh] Termos MeSH primário: Aquaporina 4/genética
Caveolina 1/genética
Edema/genética
Hipocampo/efeitos dos fármacos
Picaduras de Aranhas/genética
Venenos de Aranha/toxicidade
[Mh] Termos MeSH secundário: Fatores Etários
Animais
Animais Recém-Nascidos
Aquaporina 4/metabolismo
Astrócitos/efeitos dos fármacos
Astrócitos/metabolismo
Astrócitos/patologia
Transporte Biológico
Barreira Hematoencefálica/efeitos dos fármacos
Barreira Hematoencefálica/metabolismo
Barreira Hematoencefálica/patologia
Caveolina 1/metabolismo
Edema/induzido quimicamente
Edema/metabolismo
Edema/patologia
Regulação da Expressão Gênica
Hipocampo/metabolismo
Hipocampo/patologia
Injeções Intraperitoneais
Masculino
Ratos
Ratos Wistar
Transdução de Sinais
Picaduras de Aranhas/induzido quimicamente
Picaduras de Aranhas/metabolismo
Picaduras de Aranhas/patologia
Venenos de Aranha/administração & dosagem
Venenos de Aranha/isolamento & purificação
Aranhas/química
Aranhas/patogenicidade
Água/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Aqp4 protein, rat); 0 (Aquaporin 4); 0 (Cav1 protein, rat); 0 (Caveolin 1); 0 (Spider Venoms); 059QF0KO0R (Water)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170330
[Lr] Data última revisão:
170330
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161126
[St] Status:MEDLINE


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[PMID]:27846029
[Au] Autor:Hadanny A; Fishlev G; Bechor Y; Meir O; Efrati S
[Ti] Título:Nonhealing Wounds Caused by Brown Spider Bites: Application of Hyperbaric Oxygen Therapy.
[So] Source:Adv Skin Wound Care;29(12):560-566, 2016 Dec.
[Is] ISSN:1538-8654
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Bites by Loxosceles spiders (also known as recluse spiders or brown spiders) can cause necrotic ulcerations of various sizes and dimensions. The current standard of care for brown spider bites includes analgesics, ice, compression, elevation, antihistamines, and surgical debridement. Hyperbaric oxygen therapy (HBOT) in the treatment of brown spider bites has been administered in the early stage of ulceration, or 2 to 6 days after the bite. Unfortunately, the diagnosis of spider bite-related ulcers is often delayed and weeks or months may elapse before HBOT is considered. OBJECTIVE: To evaluate the effect of HBOT on nonhealing wounds caused by brown spider bites in the late, chronic, nonhealing stage. METHODS: Analysis of 3 patients with brown spider-bite healing wounds treated at The Sagol Center for Hyperbaric Medicine and Research in Israel. Patients presented 2 to 3 months after failure of other therapies including topical dressings, antibiotics, and corticosteroids. All patients were treated with daily 2 ATA (atmospheres absolute) with 100% oxygen HBOT sessions. RESULTS: All 3 patients were previously healthy without any chronic disease. Their ages were 30, 42, and 73 years. They were treated once daily for 13, 17, and 31 sessions, respectively. The wounds of all 3 patients healed, and there was no need for additional surgical intervention. There were no significant adverse events in any of the patients. CONCLUSIONS: Microvascular injury related to brown spider bites may culminate in ischemic nonhealing wounds even in a relatively young, healthy population. Hyperbaric oxygen therapy should be considered as a valuable therapeutic tool even months after the bite.
[Mh] Termos MeSH primário: Oxigenação Hiperbárica
Picaduras de Aranhas/terapia
[Mh] Termos MeSH secundário: Adulto
Idoso
Animais
Aranha Marrom Reclusa
Feminino
Seres Humanos
Masculino
Picaduras de Aranhas/patologia
Cicatrização
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170713
[Lr] Data última revisão:
170713
[Sb] Subgrupo de revista:N
[Da] Data de entrada para processamento:161116
[St] Status:MEDLINE


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[PMID]:27692235
[Au] Autor:Boissiere F; Masson R; Fluieraru S; Vitse J; Dessena L; Lefevre M; Bekara F; Herlin C
[Ad] Endereço:Département de chirurgie plastique et reconstructrice, CHRU Lapeyronie, 34295 Montpellier, France; Centre de traitement des brûlés, CHRU Lapeyronie, 34295 Montpellier, France; Unité médico-chirurgicale de plaies et cicatrisation, CHRU Picardie, 34295 Amiens, France.
[Ti] Título:[Cutaneous loxoscelism, about an exceptional observation of 9 consecutive cases].
[Ti] Título:Le loxoscelisme cutané, à propos d'une observation exceptionnelle de 9 cas consécutifs..
[So] Source:Ann Chir Plast Esthet;61(6):811-819, 2016 Dec.
[Is] ISSN:1768-319X
[Cp] País de publicação:France
[La] Idioma:fre
[Ab] Resumo:INTRODUCTION: Loxosceles spiders are ubiquitous and responsible for many cases of envenomation in the world. The kind rufescens is present in the Provence and Occitan regions in France. During the summer 2015, we faced many Loxosceles rufescens cases of bites having led to extensive integumental necrosis whose features and singular evolution seems important to report. MATERIAL AND METHODS: We report the cases of nine patients who experienced a spider bite in the summer of 2015 in the Languedoc Roussillon. RESULTS: Of nine patients, eight patients had skin necrosis and five required surgical care. Five patients had a fever and had five other general signs such as important asthenia, joint pain, nausea and dizziness. CRP was very low normal in all patients. Finally, five of the nine patients reported a residual pain. DISCUSSION: L. rufescens is a small spider (7 to 15mm in diameter) having a cytotoxic venom. Loxoscelism diagnosis is usually made by removing a front necrotic skin lesion. Of systemic loxoscelism that have been described, some American species had fatal outcomes. The treatment remains controversial with various options: surgery, antibiotics, antihistaminics, antivenom. CONCLUSION: The diagnosis must be made in endemic areas when confronted to a necrosic integumentary infectious rapidly progressive, unresponsive to antibiotic treatment associated with atypical general signs.
[Mh] Termos MeSH primário: Aranha Marrom Reclusa
Pele/patologia
Picaduras de Aranhas/complicações
[Mh] Termos MeSH secundário: Adulto
Animais
Feminino
Seres Humanos
Meia-Idade
Necrose/etiologia
Necrose/cirurgia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170614
[Lr] Data última revisão:
170614
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161004
[St] Status:MEDLINE


  10 / 1079 MEDLINE  
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[PMID]:27604938
[Au] Autor:Afshari R
[Ad] Endereço:BC Centre for Disease Control, Vancouver, Canada.
[Ti] Título:Arthropods: Bite like a spider, sting like a scorpion.
[So] Source:Nature;537(7619):167, 2016 09 08.
[Is] ISSN:1476-4687
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Picadas de Escorpião
Escorpiões/fisiologia
Picaduras de Aranhas
Aranhas/fisiologia
[Mh] Termos MeSH secundário: Animais
Seres Humanos
Picadas de Escorpião/diagnóstico
Picaduras de Aranhas/diagnóstico
[Pt] Tipo de publicação:LETTER
[Em] Mês de entrada:1610
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160909
[St] Status:MEDLINE
[do] DOI:10.1038/537167e



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