Base de dados : MEDLINE
Pesquisa : C25.723.680 [Categoria DeCS]
Referências encontradas : 386 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 39 ir para página                         

  1 / 386 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28335412
[Au] Autor:Gómez-Espinosa D; Cervantes-Aguilar FJ; Del Río-García JC; Villarreal-Barajas T; Vázquez-Durán A; Méndez-Albores A
[Ad] Endereço:National Autonomous University of Mexico-Superior Studies Faculty at Cuautitlan (UNAM-FESC), Master in Animal Production and Health Sciences, Cuautitlan Izcalli 54714, Mexico. denisegoes1985@gmail.com.
[Ti] Título:Ameliorative Effects of Neutral Electrolyzed Water on Growth Performance, Biochemical Constituents, and Histopathological Changes in Turkey Poults during Aflatoxicosis.
[So] Source:Toxins (Basel);9(3), 2017 Mar 14.
[Is] ISSN:2072-6651
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:Different in vitro and in silico approaches from our research group have demonstrated that neutral electrolyzed water (NEW) can be used to detoxify aflatoxins. The objective of this investigation was to evaluate the ability of NEW to detoxify B-aflatoxins (AFB1 and AFB2) in contaminated maize and to confirm detoxification in an in vivo experimental model. Batches of aflatoxin-contaminated maize were detoxified with NEW and mixed in commercial feed. A total of 240 6-day-old female large white Nicholas-700 turkey poults were randomly divided into four treatments of six replicates each (10 turkeys per replicate), which were fed ad libitum for two weeks with the following dietary treatments: (1) control feed containing aflatoxin-free maize (CONTROL); (2) feed containing the aflatoxin-contaminated maize (AF); (3) feed containing the aflatoxin-contaminated maize detoxified with NEW (AF + NEW); and (4) control feed containing aflatoxin-free maize treated with NEW (NEW). Compared to the control groups, turkey poults of the AF group significantly reduced body weight gain and increased feed conversion ratio and mortality rate; whereas turkey poults of the AF + NEW group did not present significant differences on productive parameters. In addition, alterations in serum biochemical constituents, enzyme activities, relative organ weight, gross morphological changes and histopathological studies were significantly mitigated by the aflatoxin-detoxification procedure. From these results, it is concluded that the treatment of aflatoxin-contaminated maize with NEW provided reasonable protection against the effects caused by aflatoxins in young turkey poults.
[Mh] Termos MeSH primário: Descontaminação/métodos
Micotoxicose
Perus
[Mh] Termos MeSH secundário: Aflatoxinas/metabolismo
Aflatoxinas/toxicidade
Animais
Aspartato Aminotransferases/sangue
Aspergillus flavus/isolamento & purificação
Aspergillus flavus/metabolismo
Proteínas Sanguíneas/metabolismo
Bolsa de Fabricius/efeitos dos fármacos
Bolsa de Fabricius/patologia
Eletrólise
Feminino
Fígado/efeitos dos fármacos
Fígado/patologia
Micotoxicose/metabolismo
Micotoxicose/patologia
Micotoxicose/veterinária
Baço/efeitos dos fármacos
Baço/patologia
Perus/sangue
Perus/crescimento & desenvolvimento
Água
Zea mays/microbiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Aflatoxins); 0 (Blood Proteins); 059QF0KO0R (Water); EC 2.6.1.1 (Aspartate Aminotransferases)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171109
[Lr] Data última revisão:
171109
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170325
[St] Status:MEDLINE


  2 / 386 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
[PMID]:27593392
[Au] Autor:Golder HM; Moss N; Rogers G; Jackson B; Gannon N; Wong P; Lean IJ
[Ad] Endereço:a Scibus , 2 Broughton St, PO Box 660, Camden , NSW 2570 , Australia.
[Ti] Título:Acute photosensitisation and mortality in a herd of dairy cattle in Tasmania.
[So] Source:N Z Vet J;65(1):39-45, 2017 Jan.
[Is] ISSN:1176-0710
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:CASE HISTORY: A herd of Holstein, Jersey, or Holstein-Jersey cross lactating cattle of mixed ages presented with a sudden drop in milk yield in 94/678 cows on 3 October 2014 (Day 0). The herd was located in Gretna in the Derwent Valley (Tasmania, Australia) and had been grazing dryland pasture. CLINICAL FINDINGS: On Day 0 the cows variably showed recumbency, peracute photosensitisation, inflamed coronary bands, conjunctival erythema, periauricular oedema, distress indicated by kicking at the flank, bruxism, discomfort, weight shifting, vocalisation indicating pain and depression. Blood samples collected on Day 4 from five clinically affected cows showed high activities of aspartate aminotransferase, glutamate dehydrogenase and gamma-glutamyl transferase. Morbidity, based on the number of treated cases within 72 hours of clinical onset, was estimated at 165/678 cows (24.3%). Mortality over the first 30 days was 19/678 cows (2.8%). PATHOLOGICAL FINDINGS: Necropsies of two cows on Day 4 showed marked distension of the gall bladder and extensive icterus. Necropsies of another two cows on Day 5 showed enlarged livers with severe damage and oedema of the distal abomasum. Severe ulcerative abomasal gastritis was present in both cows. Hepatic histopathology was consistent with chronic cholangiohepatitis. MYCOTOXICOLOGY: Fifty-five different mycotoxins were detected from a barley grass (Hordeum murinum) sample from the presumably contaminated pasture. Concentrations of B-trichothecenes, fumonisins, and zearalenone metabolites from this sample were remarkably high. The leaf smut, Jamesdicksonia dactylidis, that has not been previously reported in Tasmania, was identified from the sample of barley grass, but it is not known whether the smut can produce toxins. DIAGNOSIS: Probably an undescribed peracute mycotoxicosis associated with the ingestion of contaminated dryland pasture. CLINICAL RELEVANCE: A definitive diagnosis could not be reached in this case of acute photosensitisation and mortality in dairy cattle grazing possibly contaminated dryland pasture. The findings differed from both facial eczema and acute bovine liver disease, suggesting an undescribed mycotoxicosis.
[Mh] Termos MeSH primário: Doenças dos Bovinos/epidemiologia
Micotoxicose/veterinária
Transtornos de Fotossensibilidade/veterinária
[Mh] Termos MeSH secundário: Doença Aguda
Animais
Bovinos
Doenças dos Bovinos/etiologia
Doenças dos Bovinos/mortalidade
Doenças dos Bovinos/patologia
Feminino
Vesícula Biliar/patologia
Hordeum/química
Hordeum/microbiologia
Fígado/patologia
Micotoxicose/epidemiologia
Micotoxicose/mortalidade
Micotoxicose/patologia
Micotoxinas/análise
Micotoxinas/envenenamento
Transtornos de Fotossensibilidade/epidemiologia
Transtornos de Fotossensibilidade/mortalidade
Transtornos de Fotossensibilidade/patologia
Tasmânia/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Mycotoxins)
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170208
[Lr] Data última revisão:
170208
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160906
[St] Status:MEDLINE


  3 / 386 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27648562
[Au] Autor:Schenk-Jäger KM; Egli S; Hanimann D; Senn-Irlet B; Kupferschmidt H; Büntgen U
[Ad] Endereço:National Poisons Information Centre, Tox Info Suisse, Associated Institute of the University of Zurich, Zurich, Switzerland.
[Ti] Título:Introducing Mushroom Fruiting Patterns from the Swiss National Poisons Information Centre.
[So] Source:PLoS One;11(9):e0162314, 2016.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Changes in the ecology of macrofungi are poorly understood, not only because much of their life cycle is hidden belowground, but also because experiments often miss real-world complexity and most fruitbody inventories are limited in space and time. The National Poisons Information Centre 'Tox Info Suisse' provides countrywide 24hours/7days medical advice in case of poisonings since 1966. Here, we introduce a total of 12,126 mushroom-related phone calls that were received by Tox Info Suisse between 1966 and 2014. This indirect source of mycological information is dominated by the families of Boletaceae (11%), Agaricaceae (10%) and Amanitaceae (8%), which account for ~30% of all cases. Mushroom fruiting patterns revealed by the Poisons Centre inventory statistically resemble changes in fungal phenology, productivity and diversity as reflected by the Swiss National Data Centre 'SwissFungi'. Although the newly developed Tox Info Suisse dataset provides an innovative basis for timely environmental research, caution is advised when interpreting some of the observed long-term changes and autumnal extremes. Uncertainty of the new record relates to possible data incompleteness, imprecise species description and/or identification, as well as the inclusion of cultivated and non-indigenous mushrooms. Nevertheless, we hope that the Tox Info Suisse inventory will stimulate and enable a variety of ecological-oriented follow-up studies.
[Mh] Termos MeSH primário: Agaricales
Carpóforos
Micotoxicose/etiologia
[Mh] Termos MeSH secundário: Agaricales/classificação
Clima
Carpóforos/classificação
Seres Humanos
Centros de Informação
Estações do Ano
Especificidade da Espécie
Suíça/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170811
[Lr] Data última revisão:
170811
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160921
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0162314


  4 / 386 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27172005
[Au] Autor:Pappas AC; Tsiplakou E; Tsitsigiannis DI; Georgiadou M; Iliadi MK; Sotirakoglou K; Zervas G
[Ad] Endereço:a Department of Nutritional Physiology and Feeding, Faculty of Animal Science and Aquaculture , Agricultural University of Athens , Athens , Greece.
[Ti] Título:The role of bentonite binders in single or concomitant mycotoxin contamination of chicken diets.
[So] Source:Br Poult Sci;57(4):551-8, 2016 Aug.
[Is] ISSN:1466-1799
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Concomitant presence of mycotoxins is more likely to appear than a single mycotoxicosis since many mycotoxigenic fungi grow and produce their toxic metabolites under similar conditions. The present study was designed to evaluate the efficacy of 4 mycotoxin binders to protect meat-type chickens against single and concomitant administration in the feed of two mycotoxins, namely aflatoxin B1 (AFB1) and ochratoxin A (OTA) both at concentration of 0.1 mg/kg. A total of 440 as hatched, d-old, Ross 308 broilers were reared for 42 d. There were 11 dietary treatments. Chickens were fed on either an uncontaminated basal diet, basal diet and AFB1, basal with concomitant presence of AFB1 and OTA, basal diet and three binders A, B and C (1%) with or without AFB1 or basal diet and binder D (0.5%) with or without concomitant presence of AFB1 and OTA. Performance, carcass yield and several biochemical parameters were examined. Mycotoxin concentration in liver and breast muscle samples was determined. Broiler performance under concomitant mycotoxin contamination was poorer than that under single mycotoxicosis. Mycotoxin presence increased relative heart weight compared to that of broilers fed on uncontaminated diets. Only OTA and not AFB1 was detected and only in the liver. OTA concentration was four-fold lower in broilers fed on a diet with binder compared to those fed on contaminated diets without binder. In conclusion, the study revealed that binder composition and presence or not of multiple toxins may be important factors for optimum broiler performance under mycotoxicosis.
[Mh] Termos MeSH primário: Bentonita/metabolismo
Galinhas
Dieta/veterinária
Contaminação de Alimentos/análise
Micotoxicose/veterinária
Doenças das Aves Domésticas/prevenção & controle
[Mh] Termos MeSH secundário: Aflatoxina B1/metabolismo
Ração Animal/análise
Animais
Micotoxicose/microbiologia
Micotoxicose/prevenção & controle
Ocratoxinas/metabolismo
Doenças das Aves Domésticas/microbiologia
Distribuição Aleatória
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Ochratoxins); 1302-78-9 (Bentonite); 1779SX6LUY (ochratoxin A); 9N2N2Y55MH (Aflatoxin B1)
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170123
[Lr] Data última revisão:
170123
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160513
[St] Status:MEDLINE
[do] DOI:10.1080/00071668.2016.1187712


  5 / 386 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
[PMID]:27161169
[Au] Autor:Taye W; Ayalew A; Chala A; Dejene M
[Ad] Endereço:a College of Agriculture , Wolaita Sodo University , Wolaita Sodo , Ethiopia.
[Ti] Título:Aflatoxin B and total fumonisin contamination and their producing fungi in fresh and stored sorghum grain in East Hararghe, Ethiopia.
[So] Source:Food Addit Contam Part B Surveill;9(4):237-245, 2016 Dec.
[Is] ISSN:1939-3229
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Natural contamination of sorghum grains by aflatoxin B and total fumonisin and their producing toxigenic fungi has been studied. A total of 90 sorghum grain samples were collected from small-scale farmers' threshing floors and 5-6 months later from underground pits during 2013 harvest from three districts of East Hararghe, Ethiopia. Mycotoxin analysis was done using enzyme-linked immunosorbent assay (ELISA). The limits of detection were in the range 0.01-0.03 µg kg . The results revealed that all sorghum grain samples were contaminated with both Aspergillus and Fusarium species. Aflatoxin B was detected at levels ranging from
[Mh] Termos MeSH primário: Aflatoxina B1/análise
Aspergillus/isolamento & purificação
Contaminação de Alimentos
Fumonisinas/análise
Fusarium/isolamento & purificação
Sementes/química
Sorghum/química
[Mh] Termos MeSH secundário: Aflatoxina B1/toxicidade
Agricultura/métodos
Aspergillus/crescimento & desenvolvimento
Dieta/efeitos adversos
Dieta/etnologia
Ensaio de Imunoadsorção Enzimática
Etiópia/epidemiologia
Manipulação de Alimentos
Inspeção de Alimentos
Armazenamento de Alimentos
Doenças Transmitidas por Alimentos/epidemiologia
Doenças Transmitidas por Alimentos/etnologia
Doenças Transmitidas por Alimentos/etiologia
Doenças Transmitidas por Alimentos/microbiologia
Fumonisinas/toxicidade
Fusarium/crescimento & desenvolvimento
Seres Humanos
Limite de Detecção
Micotoxicose/epidemiologia
Micotoxicose/etnologia
Micotoxicose/etiologia
Micotoxicose/microbiologia
Risco
Sementes/efeitos adversos
Sementes/microbiologia
Sorghum/efeitos adversos
Sorghum/microbiologia
Análise Espaço-Temporal
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Fumonisins); 9N2N2Y55MH (Aflatoxin B1)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170413
[Lr] Data última revisão:
170413
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160511
[St] Status:MEDLINE


  6 / 386 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27159550
[Au] Autor:Monge Mdel P; Magnoli AP; Bergesio MV; Tancredi N; Magnoli CE; Chiacchiera SM
[Ad] Endereço:a Departamento de Química, Facultad de Ciencias Exactas, Físico , Químicas y Naturales Universidad Nacional de Río Cuarto , Río Cuarto , Argentina.
[Ti] Título:Activated carbons as potentially useful non-nutritive additives to prevent the effect of fumonisin B1 on sodium bentonite activity against chronic aflatoxicosis.
[So] Source:Food Addit Contam Part A Chem Anal Control Expo Risk Assess;33(6):1043-52, 2016 Jun.
[Is] ISSN:1944-0057
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Aflatoxin B1 (AFB1) and fumonisin B1 (FB1) are mycotoxins that often co-occur in feedstuffs. The ingestion of AFB1 causes aflatoxicosis in humans and animals. Sodium bentonite (NaB), a cheap non-nutritive unselective sequestering agent incorporated in animal diets, can effectively prevent aflatoxicosis. Fumonisins are responsible for equine leukoencephalomalacia and porcine pulmonary oedema, and often have subclinical toxic effects in poultries. Fumonisin B1 and aflatoxin B1 are both strongly adsorbed in vitro on sodium bentonite. Co-adsorption studies, carried out with a weight ratio of FB1 to AFB1 that mimics the natural occurrence (200:1), showed that FB1 greatly decreases the in vitro ability of NaB to adsorb AFB1. The ability of two activated carbons to adsorb FB1 was also investigated. Both carbons showed high affinity for FB1. A complex behaviour of the FB1 adsorption isotherms with pH was observed. In vitro results suggest that under natural contamination levels of AFB1 and FB1, a mixture of activated carbon and sodium bentonite might be potentially useful for prevention of sub-acute aflatoxicosis.
[Mh] Termos MeSH primário: Aflatoxina B1/antagonistas & inibidores
Bentonita/uso terapêutico
Carvão Vegetal/administração & dosagem
Aditivos Alimentares
Micotoxicose/veterinária
[Mh] Termos MeSH secundário: Adsorção
Aflatoxina B1/química
Ração Animal/análise
Animais
Bentonita/química
Carvão Vegetal/química
Eucalyptus
Contaminação de Alimentos/análise
Doenças dos Cavalos/induzido quimicamente
Doenças dos Cavalos/prevenção & controle
Cavalos
Seres Humanos
Micotoxicose/prevenção & controle
Doenças das Aves Domésticas/induzido quimicamente
Doenças das Aves Domésticas/prevenção & controle
Suínos
Doenças dos Suínos/induzido quimicamente
Doenças dos Suínos/prevenção & controle
Madeira
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Food Additives); 1302-78-9 (Bentonite); 16291-96-6 (Charcoal); 9N2N2Y55MH (Aflatoxin B1)
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170223
[Lr] Data última revisão:
170223
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160510
[St] Status:MEDLINE
[do] DOI:10.1080/19440049.2016.1185923


  7 / 386 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27044011
[Au] Autor:Hussain Z; Rehman HU; Manzoor S; Tahir S; Mukhtar M
[Ad] Endereço:Department of Livestock and Dairy Development, Poultry Production Wing, Faisalabad, Pakistan.
[Ti] Título:Determination of liver and muscle aflatoxin B1 residues and select serum chemistry variables during chronic aflatoxicosis in broiler chickens.
[So] Source:Vet Clin Pathol;45(2):330-4, 2016 Jun.
[Is] ISSN:1939-165X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Aflatoxins are secondary metabolites of the fungus Aspergillus sp. The presence of aflatoxin in poultry feeds results in direct toxicity and economic losses, and human health hazards after consumption of contaminated liver and meat. OBJECTIVES: The study was conducted to assess tissue residues of aflatoxin B1 (AFB1), and alterations in select clinical chemistry variables in serum during chronic aflatoxicosis in broiler chicks fed different dietary levels of AFB1. MATERIALS AND METHODS: Six groups of broiler chickens were fed diets containing between 0 and 800 ppb of AFB1 for 28 days. Groups of birds were terminated on days 0, 5, 13, 15, 20, and 28, and AFB1 levels were determined by HPLC in liver and muscle. Serum activities of ALT and ALP, and total protein and albumin concentrations were determined. RESULTS: No AFB1 residues were detected in liver after 50 ppb AFB1, and muscle after 50 and 100 ppb AFB1 feeding. Residues above the permissible threshold (> 2.0 ng/g) were only detected in liver tissues of groups fed 400 ppb and 800 ppb AFB1 in feed. The ALT and ALP activities in treated groups were significantly higher, and total protein and albumin concentrations were significantly lower in all treated groups compared to controls. CONCLUSIONS: Continuous feeding of AFB1 to broiler chicken at levels of 50 and 100 ppb for 28 days did not reveal measurable AFB1 residues in muscle tissues. Serum values of ALT, ALP, total protein, and albumin may serve as markers for chronic aflatoxicosis in affected poultry.
[Mh] Termos MeSH primário: Aflatoxina B1/análise
Micotoxicose/veterinária
Doenças das Aves Domésticas/metabolismo
[Mh] Termos MeSH secundário: Animais
Galinhas
Doença Crônica
Fígado/metabolismo
Músculo Esquelético/metabolismo
Micotoxicose/sangue
Micotoxicose/metabolismo
Doenças das Aves Domésticas/sangue
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
9N2N2Y55MH (Aflatoxin B1)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170404
[Lr] Data última revisão:
170404
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160405
[St] Status:MEDLINE
[do] DOI:10.1111/vcp.12336


  8 / 386 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:26957625
[Au] Autor:Chen X; Zhang Q; Applegate TJ
[Ad] Endereço:Department of Animal Sciences, Purdue University, West Lafayette, IN 47906.
[Ti] Título:Impact of dietary branched chain amino acids concentration on broiler chicks during aflatoxicosis.
[So] Source:Poult Sci;95(6):1281-9, 2016 Jun 01.
[Is] ISSN:1525-3171
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:A 20-day trial was conducted to determine the effects of dietary branched-chain amino acids (BCAA) on performance, nutrient digestibility, and gene expression of the mTOR pathway in broiler chicks when exposed to aflatoxin B1 (AFB1). The 6 dietary treatments were arranged in a 2 × 3 factorial with 3 BCAA concentrations (1.16, 1.94, and 2.73%) with or without 1.5 mg/kg AFB1 (1.77 mg/kg analyzed). Each diet was fed to 8 replicate cages (6 chicks per cage) from 6 to 20 d of age. Exposure to AFB1 significantly reduced gain:feed ratio and breast muscle weight (P < 0.05), and tended to decrease cumulative BW gain (P = 0.087), while increasing dietary BCAA improved all performance measures (P ≤ 0.0002), except relative breast muscle weight. Apparent ileal digestibility of N and 9 amino acids were increased by AFB1 (P ≤ 0.05), but were reduced by higher dietary BCAA (P ≤ 0.023). Jejunum histology was not affected by AFB1, while higher dietary BCAA tended to increase villus height (P = 0.08). Additionally, the gene expression of mTOR pathway (mTOR, 4EBP1, and S6K1) from liver and jejunum were not affected by dietary treatments, while muscle expression of S6K1 tended to be increased by AFB1 (P = 0.07). No significant interaction between AFB1 and dietary BCAA were observed for any measures in the current study. Results from this study suggested that feed AFB1 contamination can significantly reduce growth performance and breast muscle growth in broiler chicks at 20 d. Higher BCAA supply may have beneficial impact on bird performance, but this effect is independent of AFB1 exposure.
[Mh] Termos MeSH primário: Aflatoxina B1/farmacologia
Aminoácidos de Cadeia Ramificada/metabolismo
Galinhas
Micotoxicose/veterinária
Doenças das Aves Domésticas/microbiologia
[Mh] Termos MeSH secundário: Aminoácidos de Cadeia Ramificada/administração & dosagem
Ração Animal/análise
Fenômenos Fisiológicos da Nutrição Animal
Animais
Proteínas Aviárias/genética
Proteínas Aviárias/metabolismo
Galinhas/crescimento & desenvolvimento
Dieta/veterinária
Relação Dose-Resposta a Droga
Doenças Transmitidas por Alimentos/sangue
Doenças Transmitidas por Alimentos/genética
Doenças Transmitidas por Alimentos/microbiologia
Doenças Transmitidas por Alimentos/veterinária
Expressão Gênica
Micotoxicose/sangue
Micotoxicose/genética
Micotoxicose/microbiologia
Doenças das Aves Domésticas/sangue
Doenças das Aves Domésticas/genética
Distribuição Aleatória
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Amino Acids, Branched-Chain); 0 (Avian Proteins); 9N2N2Y55MH (Aflatoxin B1)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170406
[Lr] Data última revisão:
170406
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160310
[St] Status:MEDLINE
[do] DOI:10.3382/ps/pew061


  9 / 386 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:26947348
[Au] Autor:Uyar A; Yener Z; Dogan A
[Ad] Endereço:a Department of Pathology, Faculty of Veterinary Medicine , Yuzuncu Yil University , Van , Turkey.
[Ti] Título:Protective effects of Urtica dioica seed extract in aflatoxicosis: histopathological and biochemical findings.
[So] Source:Br Poult Sci;57(2):235-45, 2016 Apr.
[Is] ISSN:1466-1799
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The ameliorative potential and antioxidant capacity of an extract of Urtica dioica seeds (UDS) was investigated using histopathological changes in liver and kidney, measuring serum marker enzymes, antioxidant defence systems and lipid peroxidation (malondialdehyde (MDA)) content in various tissues of broilers exposed to aflatoxin (AF). A total of 32 broilers were divided randomly into 4 groups: control, UDS extract-treated, AF-treated and AF+UDS extract-treated. Broilers in control and UDS extract-treated groups were fed on a diet without AF. The AF-treated group and AF+UDS extract-treated groups were treated with an estimated 1 mg total AF/kg feed. The AF+UDS extract groups received in addition 30 ml UDS extract/kg diet for 21 d. The AF-treated group had significantly decreased body weight gain when compared to the other groups. Biochemical analysis showed a small increase in the concentrations of serum aspartate aminotransferase, alanine aminotransferase, gamma glutamyl transpeptidase and lactate dehydrogenase in the AF-treated group compared to that of the control group, whereas concentrations of these enzymes were decreased in the AF+UDS group compared to that of the AF-treated group. Administration of supplementary UDS extract helped restore the AF-induced increase in MDA and reduced the antioxidant system towards normality, particularly in the liver, brain, kidney and heart. Hepatorenal protection by UDS extracts was further supported by the almost normal histology in AF+UDS extract-treated group as compared to the degenerative changes in the AF-treated broilers. It was concluded that UDS extract has a protective hepatorenal effect in broilers affected by aflatoxicosis, probably acting by promoting the antioxidative defence systems.
[Mh] Termos MeSH primário: Galinhas
Dieta/veterinária
Suplementos Nutricionais
Micotoxicose/veterinária
Extratos Vegetais/metabolismo
Doenças das Aves Domésticas/prevenção & controle
[Mh] Termos MeSH secundário: Aflatoxinas/efeitos adversos
Ração Animal/análise
Animais
Feminino
Peroxidação de Lipídeos
Fígado/enzimologia
Masculino
Micotoxicose/patologia
Micotoxicose/prevenção & controle
Especificidade de Órgãos
Extratos Vegetais/administração & dosagem
Doenças das Aves Domésticas/patologia
Distribuição Aleatória
Sementes/química
Urtica dioica/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Aflatoxins); 0 (Plant Extracts)
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170123
[Lr] Data última revisão:
170123
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160308
[St] Status:MEDLINE
[do] DOI:10.1080/00071668.2015.1129664


  10 / 386 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:26944977
[Au] Autor:Chen X; Naehrer K; Applegate TJ
[Ad] Endereço:Department of Animal Sciences, Purdue University, West Lafayette, IN 47906.
[Ti] Título:Interactive effects of dietary protein concentration and aflatoxin B1 on performance, nutrient digestibility, and gut health in broiler chicks.
[So] Source:Poult Sci;95(6):1312-25, 2016 Jun 01.
[Is] ISSN:1525-3171
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:A 20-day trial was conducted to determine the impact of aflatoxin B1 (AFB1) and dietary protein concentration on performance, nutrient digestibility, and gut health in broiler chicks. The 6 dietary treatments were arranged in a 2 × 3 factorial with 3 crude protein (CP) concentrations (16, 22, and 26%) with or without 1.5 mg/kg AFB1 Each diet was fed to 6 replicate cages (6 chicks per cage) from zero to 20 d of age. Endogenous N and amino acid loss were estimated from birds fed a N-free diet with or without 1.5 mg/kg AFB1 A significant interaction between AFB1 and CP concentration was observed for growth performance, where reduction of BW gain, feed intake, gain:feed ratio, and breast muscle weight by AFB1 were most profound in birds fed the 16%-CP diet, and were completely eliminated when birds were fed the 26%-CP diet (AFB1 by CP interaction; P ≤ 0.023). Similarly, AFB1 reduced serum albumin, total protein, and globulin concentrations in birds fed 16 and 22% CP diets, but not in those fed the 26%-CP (AFB1 by CP interaction; P ≤ 0.071). Gut permeability was increased in birds fed AFB1-contamiated diets as measured by serum lactulose/rhamnose ratio (main effect; P = 0.04). Additionally, AFB1 tended to increase endogenous N loss (P = 0.09), and significantly reduced apparent ileal digestible energy and standardized ileal N and amino acid digestibility in birds fed the 16%-CP diet, while birds fed higher dietary CP were not affected (AFB1 by CP interaction; P ≤ 0.01). Further, AFB1 increased the translation initiation factor 4E-binding protein (4EBP1), claudin1, and multiple jejunal amino acid transporters expression (main effect; P ≤ 0.04). Results from this study indicate that a 1.5 mg AFB1/kg diet significantly impairs growth, major serum biochemistry measures, gut barrier, endogenous loss, and energy and amino acid digestibility. Aflatoxicosis can be augmented by low dietary CP, while higher dietary CP completely eliminated the impairment of performance, serum proteins, and nutrient digestibility from aflatoxicosis in zero to 20 d broiler chicks.
[Mh] Termos MeSH primário: Aflatoxina B1/toxicidade
Galinhas
Proteínas na Dieta/farmacologia
Micotoxicose/veterinária
Doenças das Aves Domésticas/dietoterapia
[Mh] Termos MeSH secundário: Aflatoxina B1/administração & dosagem
Ração Animal/análise
Fenômenos Fisiológicos da Nutrição Animal/efeitos dos fármacos
Animais
Galinhas/crescimento & desenvolvimento
Dieta/veterinária
Proteínas na Dieta/administração & dosagem
Digestão/efeitos dos fármacos
Relação Dose-Resposta a Droga
Trato Gastrointestinal/efeitos dos fármacos
Trato Gastrointestinal/fisiologia
Micotoxicose/dietoterapia
Micotoxicose/microbiologia
Doenças das Aves Domésticas/microbiologia
Distribuição Aleatória
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Dietary Proteins); 9N2N2Y55MH (Aflatoxin B1)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170406
[Lr] Data última revisão:
170406
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160306
[St] Status:MEDLINE
[do] DOI:10.3382/ps/pew022



página 1 de 39 ir para página                         
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde