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[PMID]:29468953
[Au] Autor:Liu Y; Lintonen T; Tynjälä J; Villberg J; Välimaa R; Ojala K; Kannas L
[Ad] Endereço:1 School of Physical Education and Sport Training, Shanghai University of Sport, China.
[Ti] Título:Socioeconomic differences in the use of alcohol and drunkenness in adolescents: Trends in the Health Behaviour in School-aged Children study in Finland 1990-2014.
[So] Source:Scand J Public Health;46(1):102-111, 2018 Feb.
[Is] ISSN:1651-1905
[Cp] País de publicação:Sweden
[La] Idioma:eng
[Ab] Resumo:AIMS: The aims of this study were to explore time-based trends of socioeconomic differences in alcohol use and drunkenness in Finnish adolescents from 1990 to 2014 and to investigate the significance of two indicators in detecting socioeconomic differences in alcohol use and drunkenness. METHODS: Data were retrieved from seven surveys conducted as part of the Health Behaviour in School-aged Children (HBSC) study in Finland from 1990 to 2014. The alcohol use and drunkenness of 15-year-old students, as well as socioeconomic status, including educational aspiration and perceived family wealth, were assessed via a self-report questionnaire. Logistic regression models were used to investigate the relationships between alcohol use, drunkenness and indicators of socioeconomic status. RESULTS: The study showed that the alcohol use and drunkenness of Finnish 15-year-old adolescents have decreased since the late 1990s. However, the level of decrease is not consistent among different socioeconomic groups and socioeconomic differences in drinking behaviour between two educational aspiration groups have persisted over two decades. Girls from the groups with low perceived family wealth were more likely to be frequently drunk in the time period 2006-2014. CONCLUSIONS: This study suggests that students with low educational aspiration should be the target population for interventions aiming at reducing the alcohol use and drunkenness of Finnish adolescents. In future interventions aimed at reducing heavier drinking, adolescents (especially girls) from less wealthy families should be the first priority. Further studies on trends in socioeconomic differences in alcohol use and drunkenness in adolescence should be conducted using different indicators of socioeconomic status and other social context factors should also be taken into account.
[Mh] Termos MeSH primário: Comportamento do Adolescente
Consumo de Bebidas Alcoólicas/epidemiologia
Intoxicação Alcoólica/epidemiologia
Disparidades nos Níveis de Saúde
[Mh] Termos MeSH secundário: Adolescente
Feminino
Finlândia/epidemiologia
Comportamentos Relacionados com a Saúde
Inquéritos Epidemiológicos
Seres Humanos
Masculino
Fatores Socioeconômicos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180227
[Lr] Data última revisão:
180227
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180223
[St] Status:MEDLINE
[do] DOI:10.1177/1403494816684118


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[PMID]:29329355
[Au] Autor:Beaton LE; Azma S; Marinkovic K
[Ad] Endereço:Department of Psychology, San Diego State University, San Diego, California, United States of America.
[Ti] Título:When the brain changes its mind: Oscillatory dynamics of conflict processing and response switching in a flanker task during alcohol challenge.
[So] Source:PLoS One;13(1):e0191200, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Despite the subjective experience of being in full and deliberate control of our actions, our daily routines rely on a continuous and interactive engagement of sensory evaluation and response preparation streams. They unfold automatically and unconsciously and are seamlessly integrated with cognitive control which is mobilized by stimuli that evoke ambiguity or response conflict. Methods with high spatio-temporal sensitivity are needed to provide insight into the interplay between automatic and controlled processing. This study used anatomically-constrained MEG to examine the underlying neural dynamics in a flanker task that manipulated S-R incongruity at the stimulus (SI) and response levels (RI). Though irrelevant, flankers evoked automatic preparation of motor plans which had to be suppressed and reversed following the target presentation on RI trials. Event-related source power estimates in beta (15-25 Hz) frequency band in the sensorimotor cortex tracked motor preparation and response in real time and revealed switching from the incorrectly-primed to the correctly-responding hemisphere. In contrast, theta oscillations (4-7 Hz) were sensitive to the levels of incongruity as the medial and ventrolateral frontal cortices were especially activated by response conflict. These two areas are key to cognitive control and their integrated contributions to response inhibition and switching were revealed by phase-locked co-oscillations. These processes were pharmacologically manipulated with a moderate alcohol beverage or a placebo administered to healthy social drinkers. Alcohol selectively decreased accuracy to response conflict. It strongly attenuated theta oscillations during decision making and partly re-sculpted relative contributions of the frontal network without affecting the motor switching process subserved by beta band. Our results indicate that motor preparation is initiated automatically even when counterproductive but that it is monitored and regulated by the prefrontal cognitive control processes under conflict. They further confirm that the regulative top-down functions are particularly vulnerable to alcohol intoxication.
[Mh] Termos MeSH primário: Consumo de Bebidas Alcoólicas/fisiopatologia
Consumo de Bebidas Alcoólicas/psicologia
Encéfalo/fisiologia
Conflito (Psicologia)
[Mh] Termos MeSH secundário: Adulto
Intoxicação Alcoólica/fisiopatologia
Intoxicação Alcoólica/psicologia
Ritmo beta/efeitos dos fármacos
Ritmo beta/fisiologia
Encéfalo/diagnóstico por imagem
Encéfalo/efeitos dos fármacos
Mapeamento Encefálico
Cognição/efeitos dos fármacos
Cognição/fisiologia
Etanol/efeitos adversos
Feminino
Neuroimagem Funcional
Seres Humanos
Imagem por Ressonância Magnética
Magnetoencefalografia
Masculino
Córtex Pré-Frontal/diagnóstico por imagem
Córtex Pré-Frontal/efeitos dos fármacos
Córtex Pré-Frontal/fisiologia
Desempenho Psicomotor/efeitos dos fármacos
Desempenho Psicomotor/fisiologia
Ritmo Teta/efeitos dos fármacos
Ritmo Teta/fisiologia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL
[Nm] Nome de substância:
3K9958V90M (Ethanol)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180226
[Lr] Data última revisão:
180226
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180113
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0191200


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[PMID]:29176519
[Au] Autor:Brewer-Smyth K; Pohlig RT
[Ad] Endereço:Author Affiliations: College of Health Sciences, University of Delaware.
[Ti] Título:Risk Factors for Women Being Under the Influence of Alcohol Compared With Other Illicit Substances at the Time of Committing Violent Crimes.
[So] Source:J Forensic Nurs;13(4):186-195, 2017 Oct/Dec.
[Is] ISSN:1939-3938
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PURPOSE: We investigated women under the influence of alcohol compared with other illicit substances at the time of committing a crime to identify predictors of being under the influence of alcohol and female-enacted crime. METHODS: Analyses of data, obtained from private interviews and examinations of female prison inmates, included regression analyses exploring predictors of being under the influence of alcohol at the time of the crime and predictors of violent crime. In addition, a reanalysis of a previously reported model, predicting conviction of a violent crime, was conducted including a new variable, being under the influence of alcohol at the time of the crime. RESULTS: Those under the influence of alcohol at the time of their crime had experienced greater nonfamilial childhood sexual abuse and traumatic brain injuries with loss of consciousness predating their crime. They were more likely to have committed a violent, rather than nonviolent, crime compared with those under the influence of other substances, with the latter being not significantly different for those not under the influence of any substance. Being under the influence of alcohol increased the risk of committing a violent crime, adjusting for other predictors of female violence. CONCLUSION: Women under the influence of alcohol are at a greater risk for committing violent crimes than those under the influence of other substances. Female nonfamilial childhood sexual abuse and traumatic brain injury victims were at a higher risk for being under the influence of alcohol, in comparison with other substances, at the time of committing a violent crime.
[Mh] Termos MeSH primário: Intoxicação Alcoólica/epidemiologia
Crime
Prisioneiros/estatística & dados numéricos
Violência
[Mh] Termos MeSH secundário: Adulto
Adultos Sobreviventes de Maus-Tratos Infantis/estatística & dados numéricos
Lesões Encefálicas Traumáticas/epidemiologia
Estudos de Casos e Controles
Feminino
Seres Humanos
Fatores de Risco
Transtornos Relacionados ao Uso de Substâncias/epidemiologia
Inconsciência/epidemiologia
Estados Unidos/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1712
[Cu] Atualização por classe:180222
[Lr] Data última revisão:
180222
[Sb] Subgrupo de revista:IM; N
[Da] Data de entrada para processamento:171128
[St] Status:MEDLINE
[do] DOI:10.1097/JFN.0000000000000177


  4 / 10881 MEDLINE  
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[PMID]:29231039
[Au] Autor:Nederhoff DM; Lenk KM; Horvath KJ; Nelson TF; Ecklund AM; Erickson DJ; Toomey TL
[Ad] Endereço:1 Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, MN, USA.
[Ti] Título:Alcohol Service Practices: A Survey of Bar and Restaurant Managers.
[So] Source:J Drug Educ;46(3-4):64-81, 2016 Dec.
[Is] ISSN:1541-4159
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Excessive alcohol consumption can result from illegal sales to intoxicated patrons at bars and restaurants. We surveyed bar/restaurant managers about their practices in reducing illegal sales to intoxicated patrons. We found that managers were confident that they could refuse service to intoxicated customers but were less likely to have communicated necessary information to their staff on how to refuse such sales. Managers who agreed that a business in their community would be cited for overservice were more likely to be confident that they could handle customers who had been cut off from alcohol service. Our study suggests that bar/restaurant managers may need training to improve their communication with staff and that increased enforcement may lead to an increase in manager confidence in handling intoxicated patrons.
[Mh] Termos MeSH primário: Bebidas Alcoólicas/provisão & distribuição
Intoxicação Alcoólica/prevenção & controle
Restaurantes/legislação & jurisprudência
[Mh] Termos MeSH secundário: Adulto
Feminino
Seres Humanos
Capacitação em Serviço
Masculino
Minnesota
Inquéritos e Questionários
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180205
[Lr] Data última revisão:
180205
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171213
[St] Status:MEDLINE
[do] DOI:10.1177/0047237917724408


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[PMID]:28471244
[Au] Autor:O'Shea T; Thomas N; Webb BT; Dick DM; Kendler KS; Chartier KG
[Ad] Endereço:a Virginia Commonwealth University , School of Social Work , Richmond , VA , USA.
[Ti] Título:ALDH2*2 and peer drinking in East Asian college students.
[So] Source:Am J Drug Alcohol Abuse;43(6):678-685, 2017 Nov.
[Is] ISSN:1097-9891
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The ALDH2*2 allele (A-allele) at rs671 is more commonly carried by Asians and is associated with alcohol-related flushing, a strong adverse reaction to alcohol that is protective against drinking. Social factors, such as having friends who binge drink, also contribute to drinking in Asian youth. OBJECTIVES: This study examined the interplay between ALDH2*2, peer drinking, and alcohol consumption in college students. We hypothesized that the relationship between ALDH2*2 and standard grams of ethanol per month would vary based on the level of peer drinking. METHODS: Subjects (N = 318, 63.25% female) were East Asian college students in the United States who reported drinking alcohol. Data were from the freshman year of a university survey that included a saliva DNA sample. ALDH2*2 status was coded ALDH2*2(+) (A/G and A/A genotypes) and ALDH2*2(-) (G/G genotype). Peer drinking was students' perception of how many of their friends "got drunk". RESULTS: Main effects of ALDH2*2(-) and having more friends who got drunk were associated with greater alcohol consumption. The ALDH2*2 × peer drunkenness interaction showed a stronger positive association with alcohol consumption for ALDH2*2(-) versus ALDH2*2(+) at increasing levels of peer drunkenness. Follow-up comparisons within each peer drunkenness level identified significantly higher alcohol consumption for ALDH2*2(-) compared to ALDH2*2(+) at the all friends got drunk level. CONCLUSION: There was evidence of a stronger effect for ALDH2*2(-) compared to ALDH2*2(+) with greater alcohol use when students were more exposed to peer drinking. Findings contribute to a growing literature on the interrelationships between genetic influences and more permissive environments for alcohol consumption.
[Mh] Termos MeSH primário: Consumo de Bebidas Alcoólicas/genética
Consumo de Bebidas Alcoólicas/psicologia
Aldeído-Desidrogenase Mitocondrial/genética
Americanos Asiáticos/genética
Americanos Asiáticos/psicologia
Grupo Associado
Estudantes/psicologia
[Mh] Termos MeSH secundário: Adolescente
Intoxicação Alcoólica/genética
Intoxicação Alcoólica/psicologia
Alelos
Feminino
Genótipo
Seres Humanos
Masculino
Universidades
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
EC 1.2.1.3 (Aldehyde Dehydrogenase, Mitochondrial)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180205
[Lr] Data última revisão:
180205
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170505
[St] Status:MEDLINE
[do] DOI:10.1080/00952990.2017.1314489


  6 / 10881 MEDLINE  
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[PMID]:29239574
[Au] Autor:Karjalainen K; Lintonen T
[Ti] Título:DUI offenders may have multiple health and social problems - doctors play a central role in monitoring the use of medications affecting the central nervous system.
[So] Source:Duodecim;133(10):927-34, 2017.
[Is] ISSN:0012-7183
[Cp] País de publicação:Finland
[La] Idioma:eng
[Ab] Resumo:While the overall number of driving under the influence (DUI) cases has reduced, the proportion of drivers under the influence of medications or illicit drugs has increased. In studies based on Finnish register data sets, the factors involved in DUI have been examined with the conclusion that drunk driving may be an indication of multiple health or social problems. According to several measures, DUI offenders who had used medications, especially benzodiazepines, were ill and disadvantaged. Doctors play a central role in reducing the number of DUI cases, e.g. by treating substance abuse problems and by monitoring the use of drugs which affect the central nervous system. It is possible that a DUI offender has accumulated a number of different problems at the same time, which is why the treatment of DUI offenders should pay attention to a comprehensive mapping of the situation and the use of multidisciplinary cooperation.
[Mh] Termos MeSH primário: Intoxicação Alcoólica/epidemiologia
Sistema Nervoso Central/efeitos dos fármacos
Dirigir sob a Influência/estatística & dados numéricos
Monitoramento de Medicamentos
Papel do Médico
Transtornos Relacionados ao Uso de Substâncias/epidemiologia
[Mh] Termos MeSH secundário: Intoxicação Alcoólica/prevenção & controle
Dirigir sob a Influência/legislação & jurisprudência
Dirigir sob a Influência/prevenção & controle
Finlândia/epidemiologia
Seres Humanos
Fatores de Risco
Transtornos Relacionados ao Uso de Substâncias/prevenção & controle
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180115
[Lr] Data última revisão:
180115
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171215
[St] Status:MEDLINE


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[PMID]:28450133
[Au] Autor:Eriksson CJP; Etelälahti TJ; Apter SJ
[Ad] Endereço:Department of Public Health, Clinicum, University of Helsinki, P.O. Box 20, 00014 University of Helsinki, Helsinki, Finland. Electronic address: peter.cj.eriksson@helsinki.fi.
[Ti] Título:Corticosteroid modulation and testosterone changes during alcohol intoxication affects voluntary alcohol drinking.
[So] Source:Pharmacol Biochem Behav;157:9-15, 2017 Jun.
[Is] ISSN:1873-5177
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:A number of studies have shown that stress and an activated hypothalamic-pituitary-adrenal (HPA) axis are associated with increased voluntary alcohol drinking. Recently, associations have been found between activated HPA and hypothalamic-pituitary-gonadal (HPG) axes in alcohol-preferring AA and non-preferring ANA, F2 (crossbred second generation from original AA and ANA), and Wistar rats. The aim of the present study has been to determine the role of corticosterone and alcohol-related testosterone-effects in subsequent alcohol drinking in AA, ANA, F2 and Wistar rats. The present study comprises of four substudies presenting new analyses of existing data, by which correlations between basal corticosterone levels, changes in testosterone levels during alcohol intoxications and subsequent voluntary alcohol consumption are investigated. The results displayed positive correlations between basal corticosterone levels and subsequent alcohol-mediated testosterone elevations, which was positively associated with voluntary alcohol consumption. The results also showed a negative correlation between basal corticosterone levels and alcohol-mediated testosterone decreases, which was negatively associated with alcohol consumption. In conclusion, the present study displays novel results, according to which the HPA axis, one hand, relates to testosterone elevation (potentially causing and/or strengthening reinforcement) during alcohol intoxication, which in turn may relate to higher voluntary alcohol consumption (AA rats). Vice versa, the HPA axis may also relate to alcohol-mediated testosterone decrease (causing testosterone reduction and disinforcement) and low-alcohol drinking (ANA, F2 and Wistar rats). In addition, the present results showed that alcohol-mediated testosterone changes may also, independently of the HPA axis, correlate with voluntary alcohol drinking, which indicate the impact of genetic factors. Thus, the role of the HPA-axis may be more related to situational stress than to intrinsic factors. In further studies, it should be investigated, whether the present results also apply to stress and human alcohol drinking.
[Mh] Termos MeSH primário: Consumo de Bebidas Alcoólicas/sangue
Intoxicação Alcoólica/sangue
Corticosterona/sangue
Testosterona/sangue
[Mh] Termos MeSH secundário: Consumo de Bebidas Alcoólicas/psicologia
Intoxicação Alcoólica/psicologia
Animais
Biomarcadores/sangue
Masculino
Ratos
Ratos Wistar
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Biomarkers); 3XMK78S47O (Testosterone); W980KJ009P (Corticosterone)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180112
[Lr] Data última revisão:
180112
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170429
[St] Status:MEDLINE


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[PMID]:29185681
[Au] Autor:Huntington SA; Huntington MK
[Ti] Título:Heady Mystery: Intoxicated patient's misplaced memory hides undiscovered trauma.
[So] Source:JEMS;41(10):16-9, 2016 10.
[Is] ISSN:0197-2510
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Intoxicação Alcoólica
Traumatismos Craniocerebrais/diagnóstico
Tentativa de Suicídio
Ferimentos por Arma de Fogo/diagnóstico
[Mh] Termos MeSH secundário: Acidentes por Quedas
Traumatismos Craniocerebrais/etiologia
Diagnóstico Diferencial
Seres Humanos
Masculino
Adulto Jovem
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180108
[Lr] Data última revisão:
180108
[Sb] Subgrupo de revista:H
[Da] Data de entrada para processamento:171201
[St] Status:MEDLINE


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[PMID]:29049192
[Au] Autor:Shen CJ; Kao CH; Hsu TY; Chen CY; Lin CL; Shih HM
[Ad] Endereço:aDepartment of Emergency Medicine bSchool of Medicine, College of Medicine cGraduate Institute of Clinical Medical Science and School of Medicine, College of Medicine dDepartment of Nuclear Medicine and PET Center eDepartment of Bioinformatics and Medical Engineering, Asia University, Taichung, Taiwan Management Office for Health Data fManagement Office for Health Data, China Medical University Hospital, Taichung, Taiwan, Republic of China.
[Ti] Título:Effect of alcohol intoxication on the risk of venous thromboembolism: A nationwide retrospective cohort study.
[So] Source:Medicine (Baltimore);96(42):e8041, 2017 Oct.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:This study investigated whether alcohol intoxication (AI) increases the risk of venous thromboembolism (VTE) by using the Taiwan National Health Insurance Research Database (NHIRD).Using data from the NHIRD, we assembled 61,229 patients with acute AI and randomly selected 244,916 controls. Each patient was monitored from 2000 to 2011 to identify those who were subsequently diagnosed with deep vein thrombosis (DVT) and pulmonary embolism (PE). Cox proportional hazard regression analysis was conducted to determine the risk of VTE in the patients with AI compared with the controls.The incidence rate of DVT during the 10 years follow-up period was 9.36 per 10,000 person-years and 2.07 per 10,000 person-years in the AI and non-AI cohorts, respectively. Moreover, the incidence rate of PE was 4 per 10,000 person-years in the AI cohort and 0.93 in the non-AI cohort. After adjustment for age, sex, and comorbidities, the risks of DVT and PE were 3.40 [95% confidence interval (CI) = 2.83-4.08] and 3.53 (95% CI = 2.69-4.65)-fold higher in the AI cohort than in the non-AI cohort.An increased incidence of VTE was observed among patients with AI. Therefore, physicians should carefully estimate the risk of VTE in patients with AI.
[Mh] Termos MeSH primário: Intoxicação Alcoólica/complicações
Embolia Pulmonar/etiologia
Tromboembolia Venosa/etiologia
[Mh] Termos MeSH secundário: Adulto
Estudos de Coortes
Bases de Dados Factuais
Feminino
Seres Humanos
Incidência
Masculino
Meia-Idade
Modelos de Riscos Proporcionais
Embolia Pulmonar/epidemiologia
Análise de Regressão
Estudos Retrospectivos
Fatores de Risco
Taiwan/epidemiologia
Tromboembolia Venosa/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171122
[Lr] Data última revisão:
171122
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171020
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000008041


  10 / 10881 MEDLINE  
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[PMID]:28727525
[Au] Autor:Chihuri S; Li G
[Ad] Endereço:Both authors are with the Department of Anesthesiology, College of Physicians and Surgeons, the Department of Epidemiology, Mailman School of Public Health, and the Center for Injury Epidemiology and Prevention, Columbia University, New York, NY.
[Ti] Título:Trends in Prescription Opioids Detected in Fatally Injured Drivers in 6 US States: 1995-2015.
[So] Source:Am J Public Health;107(9):1487-1492, 2017 Sep.
[Is] ISSN:1541-0048
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: To assess the time trends in prescription opioids detected in fatally injured drivers. METHODS: We analyzed 1995 to 2015 Fatality Analysis Reporting System data from California, Hawaii, Illinois, New Hampshire, Rhode Island, and West Virginia of toxicological tests for drivers fatally injured within 1 hour of a crash (n = 36 729). We used the Cochran-Armitage test for trend to assess the statistical significance of changes in the prevalence of prescription opioids detected in these drivers over time. RESULTS: The prevalence of prescription opioids detected in fatally injured drivers increased from 1.0% (95% confidence interval [CI] = 0.5, 1.4) in 1995 to 7.2% (95% CI = 5.7, 8.8) in 2015 (Z = -9.04; P < .001). Prescription opioid prevalence was higher in female than in male drivers (4.4% vs 2.9%; P < .001). Of the drivers testing positive for prescription opioids, 30.0% had elevated blood alcohol concentrations (≥ 0.01 g/dL), and 66.9% tested positive for other drugs. CONCLUSIONS: The prevalence of prescription opioids detected in fatally injured drivers has increased in the past 2 decades. The need to assess the effect of increased prescription opioid use on traffic safety is urgent.
[Mh] Termos MeSH primário: Acidentes de Trânsito/mortalidade
Analgésicos Opioides/toxicidade
Transtornos Relacionados ao Uso de Substâncias/epidemiologia
[Mh] Termos MeSH secundário: Adulto
Intoxicação Alcoólica
Condução de Veículo/estatística & dados numéricos
Feminino
Seres Humanos
Masculino
Prevalência
Fatores Sexuais
Estados Unidos/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Analgesics, Opioid)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170822
[Lr] Data última revisão:
170822
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170721
[St] Status:MEDLINE
[do] DOI:10.2105/AJPH.2017.303902



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BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde