[PMID]: | 29305456 |
[Au] Autor: | Sprague S; Petrisor B; Jeray K; McKay P; Heels-Ansdell D; Schemitsch E; Liew S; Guyatt G; Walter SD; Bhandari M; FLOW Investigators |
[Ad] Endereço: | McMaster University, 293 Wellington Street North, Suite 110, Hamilton, Ontario L8L 8E7, Canada. |
[Ti] Título: | Wound irrigation does not affect health-related quality of life after open fractures: results of a randomized controlled trial. |
[So] Source: | Bone Joint J;100-B(1):88-94, 2018 01. |
[Is] ISSN: | 2049-4408 |
[Cp] País de publicação: | England |
[La] Idioma: | eng |
[Ab] Resumo: | AIMS: The Fluid Lavage in Open Fracture Wounds (FLOW) trial was a multicentre, blinded, randomized controlled trial that used a 2 × 3 factorial design to evaluate the effect of irrigation solution (soap normal saline) and irrigation pressure (very low low high) on health-related quality of life (HRQL) in patients with open fractures. In this study, we used this dataset to ascertain whether these factors affect whether HRQL returns to pre-injury levels at 12-months post-injury. PATIENTS AND METHODS: Participants completed the Short Form-12 (SF-12) and the EuroQol-5 Dimensions (EQ-5D) at baseline (pre-injury recall), at two and six weeks, and at three, six, nine and 12-months post-fracture. We calculated the Physical Component Score (PCS) and the Mental Component Score (MCS) of the SF-12 and the EQ-5D utility score, conducted an analysis using a multi-level generalized linear model, and compared differences between the baseline and 12-month scores. RESULTS: We found no clinically important differences between irrigating solutions or pressures for the SF-12 PCS, SF-12 MCS and EQ-5D. Irrespective of treatment, participants had not returned to their pre-injury function at 12-months for any of the three outcomes (p < 0.001). CONCLUSION: Neither the composition of the irrigation solution nor irrigation pressure applied had an effect on HRQL. Irrespective of treatment, patients had not returned to their pre-injury HRQL at 12 months post-fracture. Cite this article: 2018;100-B:88-94. |
[Mh] Termos MeSH primário: |
Fraturas Expostas/terapia Qualidade de Vida Irrigação Terapêutica/métodos
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[Mh] Termos MeSH secundário: |
Adulto Idoso Feminino Seguimentos Fixação Interna de Fraturas/métodos Fraturas Expostas/reabilitação Seres Humanos Masculino Meia-Idade Pressão Psicometria Sabões/administração & dosagem Cloreto de Sódio/administração & dosagem
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[Pt] Tipo de publicação: | JOURNAL ARTICLE; MULTICENTER STUDY; RANDOMIZED CONTROLLED TRIAL |
[Nm] Nome de substância:
| 0 (Soaps); 451W47IQ8X (Sodium Chloride) |
[Em] Mês de entrada: | 1801 |
[Cu] Atualização por classe: | 180307 |
[Lr] Data última revisão:
| 180307 |
[Sb] Subgrupo de revista: | AIM; IM |
[Da] Data de entrada para processamento: | 180107 |
[St] Status: | MEDLINE |
[do] DOI: | 10.1302/0301-620X.100B1.BJJ-2017-0955.R1 |
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