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[PMID]: 28987410 [Au] Autor: Woods A; Kuntze K; Gelman F; Halicz L; Nijenhuis I [Ad] Endereço: Department for Isotope Biogeochemistry, Helmholtz Centre for Environmental Research-UFZ, Permoserstrasse 15, D-04318, Leipzig, Germany. [Ti] Título: Variable dual carbon-bromine stable isotope fractionation during enzyme-catalyzed reductive dehalogenation of brominated ethenes. [So] Source: Chemosphere;190:211-217, 2018 Jan. [Is] ISSN: 1879-1298 [Cp] País de publicação: England [La] Idioma: eng [Ab] Resumo: The potential of compound-specific stable isotope analysis (CSIA) to characterize biotransformation of brominated organic compounds (BOCs) was assessed and compared to chlorinated analogues. Sulfurospirillum multivorans and Desulfitobacterium hafniense PCE-S catalyzed the dehalogenation of tribromoethene (TBE) to either vinyl bromide (VB) or ethene, respectively. Significantly lower isotope fractionation was observed for TBE dehalogenation by S. multivorans (ε = -1.3 ± 0.2‰) compared to D. hafniense (ε = -7.7 ± 1.5‰). However, higher fractionation was observed for dibromoethene (DBE) dehalogenation by S. multivorans (ε = -16.8 ± 1.8‰ and -21.2 ± 1.6‰ for trans- and cis-1,2- (DBE) respectively), compared to D. hafniense PCE-S (ε = -9.5 ± 1.2‰ and -14.5 ± 0.7‰ for trans-1,2-DBE and cis-1,2-DBE, respectively). Significant, but similar, bromine fractionation was observed for for S. multivorans (ε = -0.53 ± 0.15‰, -1.03 ± 0.26‰, and -1.18 ± 0.13‰ for trans-1,2-DBE, cis-1,2-DBE and TBE, respectively) and D. hafniense PCE-S (ε = -0.97 ± 0.28‰, -1.16 ± 0.36‰, and -1.34 ± 0.32‰ for cis-1,2-DBE, TBE and trans-1,2-DBE, respectively). Variable CBr dual-element slopes were estimated at Λ (ε /ε ) = 1.03 ± 0.2, 17.9 ± 5.8, and 29.9 ± 11.0 for S. multivorans debrominating TBE, cis-1,2-DBE and trans-1,2-DBE, respectively, and at 7.14 ± 1.6, 8.27 ± 3.7, and 8.92 ± 2.4 for D. hafniense PCE-S debrominating trans-1,2-DBE, TBE and cis-1,2-DBE, respectively. A high variability in isotope fractionation, which was substrate property related, was observed for S. multivorans but not D. hafniense, similar as observed for chlorinated ethenes, and may be due to rate-limiting steps preceding the bond-cleavage or differences in the reaction mechanism. Overall, significant isotope fractionation was observed and, therefore, CSIA can be applied to monitor the fate of brominated ethenes in the environment. Isotope effects differences, however, are not systematically comparable to chlorinated ethenes. [Mh] Termos MeSH primário: Bromo/química Carbono/química Desulfitobacterium/metabolismo Dibrometo de Etileno/metabolismo Halogenação [Mh] Termos MeSH secundário: Biotransformação Isótopos de Carbono/química Catálise Fracionamento Químico [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (Carbon Isotopes); 1N41638RNO (Ethylene Dibromide); 7440-44-0 (Carbon); SBV4XY874G (Bromine) [Em] Mês de entrada: 1802 [Cu] Atualização por classe: 180215 [Lr] Data última revisão: 180215 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 171009 [St] Status: MEDLINE

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[PMID]: 28743492 [Au] Autor: Ichimaru Y; Fujii T; Saito H; Sano M; Uchiyama T; Miyairi S [Ad] Endereço: School of Pharmacy, Nihon University, 7-7-1 Narashinodai, Funabashi, Chiba 274-8555, Japan. [Ti] Título: 5-Bromoindirubin 3'-(O-oxiran-2-ylmethyl)oxime: A long-acting anticancer agent and a suicide inhibitor for epoxide hydrolase. [So] Source: Bioorg Med Chem;25(17):4665-4676, 2017 09 01. [Is] ISSN: 1464-3391 [Cp] País de publicação: England [La] Idioma: eng [Ab] Resumo: Indirubin 3'-oxime (Indox (1b)) suppresses cancer cell growth (IC : 15µM towards HepG2 cells) and inhibits cell cycle-related kinases such as cyclin-dependent kinases and glycogen synthase kinase-3ß. We have previously reported that the conjugation of 1b with oxirane, a protein-reactive component, enhanced the cytotoxic activity of Indox as determined from the IC value (1.7µM) of indirubin 3'-(O-oxiran-2-ylmethyl)oxime (Epox/Ind (1c)). Here we prepared Epox/Ind derivatives with one or two halogen atoms or a methoxy group on the aromatic ring(s) of an Indox moiety and studied the structure-activity relationships of the substituent(s). We found that bromine-substitution at the 5-position on 1c or any Epox/Ind derivative(s) having bromine on the aromatic ring except Epox/6'-Br-Ind was efficient to improving anticancer activity. Of the 22 Epox/Ind derivatives, 5-bromoindirubin 3'-(O-oxiran-2-ylmethyl)oxime (Epox/5-Br-Ind (2c)) was the best anticancer agent in both short- (24h) (IC : 0.67µM) and extended-duration (72h) cultures. The high anticancer activity of 2c was partly due to it being a poor substrate and a suicide inhibitor for epoxide hydrolase as epoxide hydrolase was identified as the enzyme primarily responsible for the metabolism of 2c. [Mh] Termos MeSH primário: Antineoplásicos/química Epóxido Hidrolases/antagonistas & inibidores Indóis/química Oximas/química [Mh] Termos MeSH secundário: Antineoplásicos/metabolismo Antineoplásicos/farmacologia Sítios de Ligação Bromo/química Sobrevivência Celular/efeitos dos fármacos Epóxido Hidrolases/metabolismo Células Hep G2 Seres Humanos Indóis/metabolismo Indóis/farmacologia Cinética Simulação de Acoplamento Molecular Oximas/metabolismo Oximas/farmacologia Estrutura Terciária de Proteína Relação Estrutura-Atividade [Pt] Tipo de publicação: JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T [Nm] Nome de substância: 0 (Antineoplastic Agents); 0 (Indoles); 0 (Oximes); 0 (indirubin 3'-(O-oxiran-2-ylmethyl)oxime); EC 3.3.2.- (Epoxide Hydrolases); SBV4XY874G (Bromine) [Em] Mês de entrada: 1709 [Cu] Atualização por classe: 171208 [Lr] Data última revisão: 171208 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170727 [St] Status: MEDLINE

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[PMID]: 28774625 [Au] Autor: Langsa M; Allard S; Kristiana I; Heitz A; Joll CA [Ad] Endereço: Curtin Water Quality Research Centre, Department of Chemistry, Curtin University, Perth, Western Australia 6102, Australia; Jurusan Kimia, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Papua, Manokwari, Papua Barat 98314, Indonesia. [Ti] Título: Halogen-specific total organic halogen analysis: Assessment by recovery of total bromine. [So] Source: J Environ Sci (China);58:340-348, 2017 Aug. [Is] ISSN: 1001-0742 [Cp] País de publicação: Netherlands [La] Idioma: eng [Ab] Resumo: Determination of halogen-specific total organic halogen (TOX) is vital for studies of disinfection of waters containing bromide, since total organic bromine (TOBr) is likely to be more problematic than total organic chlorine. Here, we present further halogen-specific TOX method optimisation and validation, focusing on measurement of TOBr. The optimised halogen-specific TOX method was validated based on the recovery of model compounds covering different classes of disinfection by-products (haloacetic acids, haloacetonitriles, halophenols and halogenated benzenes) and the recovery of total bromine (mass balance of TOBr and bromide concentrations) during disinfection of waters containing dissolved organic matter and bromide. The validation of a halogen-specific TOX method based on the mass balance of total bromine has not previously been reported. Very good recoveries of organic halogen from all model compounds were obtained, indicating high or complete conversion of all organic halogen in the model compound solution through to halide in the absorber solution for ion chromatography analysis. The method was also successfully applied to monitor conversion of bromide to TOBr in a groundwater treatment plant. An excellent recovery (101%) of total bromine was observed from the raw water to the post-chlorination stage. Excellent recoveries of total bromine (92%-95%) were also obtained from chlorination of a synthetic water containing dissolved organic matter and bromide, demonstrating the validity of the halogen-specific TOX method for TOBr measurement. The halogen-specific TOX method is an important tool to monitor and better understand the formation of halogenated organic compounds, in particular brominated organic compounds, in drinking water systems. [Mh] Termos MeSH primário: Bromo/análise Poluentes Químicos da Água/análise [Mh] Termos MeSH secundário: Brometos Desinfetantes/análise Desinfecção/métodos Halogênios/análise Compostos Orgânicos/análise Purificação da Água/métodos [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (Bromides); 0 (Disinfectants); 0 (Halogens); 0 (Organic Chemicals); 0 (Water Pollutants, Chemical); SBV4XY874G (Bromine) [Em] Mês de entrada: 1708 [Cu] Atualização por classe: 170811 [Lr] Data última revisão: 170811 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170805 [St] Status: MEDLINE

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[PMID]: 28607126 [Au] Autor: Lambert JA; Carlisle MA; Lam A; Aggarwal S; Doran S; Ren C; Bradley WE; Dell'Italia L; Ambalavanan N; Ford DA; Patel RP; Jilling T; Matalon S [Ad] Endereço: From the Biochemistry, Structural and Stem Cell Biology, Graduate Biomedical Sciences (J.A.L.), Division of Molecular and Translational Biomedicine, Department of Anesthesiology and Perioperative Medicine (J.A.L., M.A.C., A.L., S.A., S.D., S.M.), Division of Neonatology, Department of Pediatrics (C. [Ti] Título: Mechanisms and Treatment of Halogen Inhalation-Induced Pulmonary and Systemic Injuries in Pregnant Mice. [So] Source: Hypertension;70(2):390-400, 2017 Aug. [Is] ISSN: 1524-4563 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: Inhalation of oxidant gases has been implicated in adverse outcomes in pregnancy, but animal models to address mechanisms and studies to identify potential pregnancy-specific therapies are lacking. Herein, we show that inhalation of bromine at 600 parts per million for 30 minutes by pregnant mice on the 15th day of embryonic development results in significantly lower survival after 96 hours than an identical level of exposure in nonpregnant mice. On the 19th embryonic day, bromine-exposed pregnant mice have increased systemic blood pressure, abnormal placental development, severe fetal growth restriction, systemic inflammation, increased levels of circulating antiangiogenic short fms-like tyrosine kinase-1, and evidence of pulmonary and cardiac injury. Treatment with tadalafil, an inhibitor of type 5 phosphodiesterase, by oral gavage 1 hour post-exposure and then once daily thereafter, attenuated systemic blood pressures, decreased inflammation, ameliorated pulmonary and cardiac injury, and improved maternal survival (from 36% to 80%) and fetal growth. These pathological changes resemble those seen in preeclampsia. Nonpregnant mice did not exhibit any of these pathological changes and were not affected by tadalafil. These findings suggest that pregnant women exposed to bromine may require particular attention and monitoring for signs of preeclampsia-like symptoms. [Mh] Termos MeSH primário: Bromo Hipertensão Lesão Pulmonar Pré-Eclâmpsia Síndrome de Resposta Inflamatória Sistêmica Tadalafila/farmacologia [Mh] Termos MeSH secundário: Animais Bromo/metabolismo Bromo/toxicidade Modelos Animais de Doenças Feminino Retardo do Crescimento Fetal/induzido quimicamente Hipertensão/tratamento farmacológico Hipertensão/metabolismo Hipertensão/fisiopatologia Exposição por Inalação/efeitos adversos Lesão Pulmonar/induzido quimicamente Lesão Pulmonar/tratamento farmacológico Lesão Pulmonar/metabolismo Lesão Pulmonar/fisiopatologia Camundongos Oxidantes/metabolismo Oxidantes/toxicidade Inibidores da Fosfodiesterase 5/farmacologia Placenta/efeitos dos fármacos Placenta/fisiopatologia Pré-Eclâmpsia/tratamento farmacológico Pré-Eclâmpsia/metabolismo Pré-Eclâmpsia/fisiopatologia Gravidez Síndrome de Resposta Inflamatória Sistêmica/induzido quimicamente Síndrome de Resposta Inflamatória Sistêmica/fisiopatologia Resultado do Tratamento [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (Oxidants); 0 (Phosphodiesterase 5 Inhibitors); 742SXX0ICT (Tadalafil); SBV4XY874G (Bromine) [Em] Mês de entrada: 1708 [Cu] Atualização por classe: 170830 [Lr] Data última revisão: 170830 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170614 [St] Status: MEDLINE [do] DOI: 10.1161/HYPERTENSIONAHA.117.09466

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[PMID]: 28477535 [Au] Autor: Zhang Z; Lin D; Li W; Gao H; Peng Y; Zheng J [Ad] Endereço: Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang 110016, PR China. [Ti] Título: Sensitive bromine-based screening of potential toxic furanoids in Dioscorea bulbifera L. [So] Source: J Chromatogr B Analyt Technol Biomed Life Sci;1057:1-14, 2017 Jul 01. [Is] ISSN: 1873-376X [Cp] País de publicação: Netherlands [La] Idioma: eng [Ab] Resumo: Numerous furanoids have been reported to be toxic, and many of them were found in herbal medicines. Toxicities of furanoids are suggested to result from the generation of cis-enedials via biotransformation. The detection of the electrophilic metabolic intermediates is a challenge. Earlier, we developed a selective approach to screen potential toxic furanoids, through which we found two major furanoids, diosbulbin B and 8-epidiosbulbin E acetate, in Dioscorea bulbifera L., a known furanoid-containing and hepatotoxic herbal medicine. In the present study, we improved the approach to analyze furanoids in D. bulbifera L., which allowed us to detect additional six potential furanoids, including diosbulbin A, diosbulbin D, diosbulbin E, diosbulbin F, diosbulbin M, and diosbulbin D glycoside. The achievements of this study enhanced the sensitivity to screen potential toxic furanoids through elevating S/N values by approximately 3 times. This will facilitate the understanding of mechanisms of toxic actions of D. bulbifera L. and other furanoid-containing toxic herbal medicines. [Mh] Termos MeSH primário: Bromo Dioscorea/química Diterpenos/análise Furanos/análise Compostos Heterocíclicos de 4 ou mais Anéis/análise Lactonas/análise [Mh] Termos MeSH secundário: Animais Bromo/análise Bromo/química Células Cultivadas Medicamentos de Ervas Chinesas/efeitos adversos Medicamentos de Ervas Chinesas/química Microssomos Hepáticos/química Extratos Vegetais/química Extratos Vegetais/toxicidade Ratos Ratos Sprague-Dawley Sensibilidade e Especificidade Espectrometria de Massas em Tandem Testes de Toxicidade [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (8-epidiosbulbin E acetate); 0 (Diterpenes); 0 (Drugs, Chinese Herbal); 0 (Furans); 0 (Heterocyclic Compounds, 4 or More Rings); 0 (Lactones); 0 (Plant Extracts); 20086-06-0 (diosbulbin B); SBV4XY874G (Bromine) [Em] Mês de entrada: 1707 [Cu] Atualização por classe: 170718 [Lr] Data última revisão: 170718 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170507 [St] Status: MEDLINE

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[PMID]: 28372837 [Au] Autor: Liu L; Liu A; Zhang Q; Shi J; He B; Yun Z; Jiang G [Ad] Endereço: State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China; College of Resources and Environment, University of Chinese Academy of Sciences, Beijing 100049, China. [Ti] Título: Determination of tetrabromobisphenol-A/S and their main derivatives in water samples by high performance liquid chromatography coupled with inductively coupled plasma tandem mass spectrometry. [So] Source: J Chromatogr A;1497:81-86, 2017 May 12. [Is] ISSN: 1873-3778 [Cp] País de publicação: Netherlands [La] Idioma: eng [Ab] Resumo: As the most widely used brominated flame retardants (BFRs), Tetrabromobisphenol-A (TBBPA) as well as its alternative Tetrabromobisphenol-S (TBBPS) and their derivatives have raised wide concerns due to their adverse effects on human health and hence the sensitive detection of those BFRs was urgently needed. Herein, a novel analytical method based on high-performance liquid chromatography (HPLC) coupled with inductively coupled plasma tandem mass spectrometry (ICP-MS/MS) has been developed for the determination of TBBPA/S and their derivatives, including TBBPA-bis(2-hydroxyethyl ether) (TBBPA-BHEE), TBBPA-bis(allylether) (TBBPA-BAE), TBBPA-bis(glycidyl ether) (TBBPA-BGE), TBBPA-bis(2,3-dibromopropyl ether) (TBBPA-BDBPE) and TBBPS-bis(2,3-dibromopropyl ether) (TBBPS-BDBPE) in water samples. After optimization, the TBBPA/S and their derivatives, especially the TBBPA-BAE and TBBPA-BDBPE were simultaneously and sensitively quantified by determination of bromine (m/z=79) by using the ICP-MS. The instrument limits of detection (LODs) for the TBBPA, TBBPA-BHEE, TBBPA-BGE, TBBPA-BAE, TBBPA-BDBPE, TBBPS and TBBPS-BDBPE were determined to be 0.12, 0.14, 0.19, 0.14, 0.12, 0.17 and 0.13µgL , respectively, which was close to or much better than the reported methods. The relative standard deviations (RSDs, n=5) of peak area and retention time were better than 2.2% and 0.2% for intra-day analysis, indicating good repeatability and high precision. The proposed method had been successfully applied for the analysis of TBBPA/S and their derivatives in water samples with satisfactory recoveries (67.7%-113%). [Mh] Termos MeSH primário: Retardadores de Chama/análise Bifenil Polibromatos/análise Bifenil Polibromatos/química Espectrometria de Massas em Tandem/métodos Água/química [Mh] Termos MeSH secundário: Bromo/análise Bromo/química Cromatografia Líquida de Alta Pressão Halogenação Limite de Detecção [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (Flame Retardants); 0 (Polybrominated Biphenyls); 059QF0KO0R (Water); FQI02RFC3A (tetrabromobisphenol A); SBV4XY874G (Bromine) [Em] Mês de entrada: 1705 [Cu] Atualização por classe: 170509 [Lr] Data última revisão: 170509 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170405 [St] Status: MEDLINE

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[PMID]: 28365503 [Au] Autor: Ukisu Y [Ad] Endereço: National Institute of Advanced Industrial Science and Technology (AIST), AIST Tsukuba West, 16-1 Onogawa, Tsukuba, Ibaraki, 305-8569, Japan. Electronic address: y-ukisu@aist.go.jp. [Ti] Título: Complete catalytic debromination of hexabromocyclododecane using a silica-supported palladium catalyst in alkaline 2-propanol. [So] Source: Chemosphere;179:179-184, 2017 Jul. [Is] ISSN: 1879-1298 [Cp] País de publicação: England [La] Idioma: eng [Ab] Resumo: Although the brominated flame retardant 1,2,5,6,9,10-hexabromocyclododecane (HBCD) has been widely used to reduce the flammability of polymeric materials, it is a toxic and persistent organic compound. In this paper, we report an efficient method for the debromination of HBCD by using a Pd-catalyzed system. HBCD was completely debrominated to the C cyclic compounds such as cyclododecatriene, cyclododecadiene, and cyclododecene in a solution of 2-propanol/methanol (99:1, v/v) containing dissolved NaOH in the presence of a silica-supported Pd catalyst (Pd/SiO ) at 35 °C. The reaction achieved product yields of 92% for the bromine-free products and 94% for the released Br ions. In the absence of Pd/SiO , HBCD was partially debrominated to yield penta-, tetra-, and tribrominated C cyclic compounds. The HBCD debromination pathway seems to involve both HBr elimination by reaction with NaOH and Pd-catalyzed hydrodebromination by hydrogen transfer from 2-propanol. [Mh] Termos MeSH primário: Recuperação e Remediação Ambiental/métodos Retardadores de Chama Halogenação Hidrocarbonetos Bromados/química Hidrocarbonetos Cíclicos/síntese química [Mh] Termos MeSH secundário: 2-Propanol Bromo Catálise Hidrogênio/química Metanol Paládio/química Dióxido de Silício [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (Flame Retardants); 0 (Hydrocarbons, Brominated); 0 (Hydrocarbons, Cyclic); 5I9835JO3M (hexabromocyclododecane); 5TWQ1V240M (Palladium); 7631-86-9 (Silicon Dioxide); 7YNJ3PO35Z (Hydrogen); ND2M416302 (2-Propanol); SBV4XY874G (Bromine); Y4S76JWI15 (Methanol) [Em] Mês de entrada: 1706 [Cu] Atualização por classe: 170607 [Lr] Data última revisão: 170607 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170403 [St] Status: MEDLINE

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[PMID]: 28358483 [Au] Autor: Langsa M; Heitz A; Joll CA; von Gunten U; Allard S [Ad] Endereço: Curtin Water Quality Research Centre, Department of Chemistry, Curtin University , GPO Box U1987, Perth, Western Australia 6845, Australia. [Ti] Título: Mechanistic Aspects of the Formation of Adsorbable Organic Bromine during Chlorination of Bromide-containing Synthetic Waters. [So] Source: Environ Sci Technol;51(9):5146-5155, 2017 May 02. [Is] ISSN: 1520-5851 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: During chlorination of bromide-containing waters, a significant formation of brominated disinfection byproducts is expected. This is of concern because Br-DBPs are generally more toxic than their chlorinated analogues. In this study, synthetic water samples containing dissolved organic matter (DOM) extracts and bromide were treated under various disinfection scenarios to elucidate the mechanisms of Br-DBP formation. The total concentration of Br-DBPs was measured as adsorbable organic bromine (AOBr). A portion of the bromine (HOBr) was found to react with DOM via electrophilic substitution (≤40%), forming AOBr, and the remaining HOBr reacted with DOM via electron transfer with a reduction of HOBr to bromide (≥60%). During chlorination, the released bromide is reoxidized (recycled) by chlorine to HOBr, leading to further electrophilic substitution of unaltered DOM sites and chlorinated DOM moieties. This leads to an almost complete bromine incorporation to DOM (≥87%). The type of DOM (3.06 ≤ SUVA ≤ 4.85) is not affecting this process, as long as the bromine-reactive DOM sites are in excess and a sufficient chlorine exposure is achieved. When most reactive sites were consumed by chlorine, Cl-substituted functional groups (Cl-DOM) are reacting with HOBr by direct bromination leading to Br-Cl-DOM and by bromine substitution of chlorine leading to Br-DOM. The latter finding was supported by hexachlorobenzene as a model compound from which bromoform was formed during HOBr treatment. To better understand the experimental findings, a conceptual kinetic model allowing to assess the contribution of each AOBr pathway was developed. A simulation of distribution system conditions with a disinfectant residual of 1 mgC L showed complete conversion of Br to AOBr, with about 10% of the AOBr formed through chlorine substitution by bromine. [Mh] Termos MeSH primário: Brometos/química Bromo/química [Mh] Termos MeSH secundário: Desinfecção Halogenação Água/química Poluentes Químicos da Água Purificação da Água [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (Bromides); 0 (Water Pollutants, Chemical); 059QF0KO0R (Water); SBV4XY874G (Bromine) [Em] Mês de entrada: 1706 [Cu] Atualização por classe: 170621 [Lr] Data última revisão: 170621 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170331 [St] Status: MEDLINE [do] DOI: 10.1021/acs.est.7b00691

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[PMID]: 28355273 [Au] Autor: Huang G; Wang M; Hu Y; Lv S; Li C [Ad] Endereço: School of Environment and Energy, South China University of Technology, the Key Lab of Pollution Control and Ecosystem Restoration in Industry Clusters, Ministry of Education, Guangzhou, PR China. [Ti] Título: Synthesis, characterization, and debromination reactivity of cellulose-stabilized Pd/Fe nanoparticles for 2,2',4,4'-tretrabromodiphenyl ether. [So] Source: PLoS One;12(3):e0174589, 2017. [Is] ISSN: 1932-6203 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: In this study, two kinds of cellulose derivatives (polyanionic cellulose (PAC) and hydroxypropylmethyl cellulose (HPMC)) were selected as stabilizers of Pd/Fe nanoparticles (NPs) to investigate their influences on the debromination performances of 2,2',4,4'-tretrabromodiphenyl ether (BDE47). Field emission scanning electron microscope (FE-SEM) images revealed that the cellulose-stabilized Pd/Fe NPs were smaller and more uniform than the bare-Pd/Fe NPs. X-ray diffractometer (XRD) and X-ray photoelectron spectroscopy (XPS) results suggested that cellulose coatings found on Pd/Fe NPs surfaces featured some antioxidation abilities, which followed the order of HPMC < PAC. Sedimentation tests demonstrated that the stabilizing power of PAC for Pd/Fe NPs was higher than that of HPMC. Fourier transfer infrared spectrometer (FTIR) results indicated that PAC molecules were bound to the Pd/Fe NPs surfaces by polar covalent bonds and hydrogen bonds, while HPMC molecules interacted with the nanoparticles by hydrogen bonds. Batch debromination test for BDE47 demonstrated that the catalytic debromination rate with cellulose-stabilized Pd/Fe NPs was higher than that with bare-Pd/Fe NPs during reaction period of 15 min. Overall, this study indicated that both celluloses are beneficial to forming smaller, more regular, stable and antioxidative Pd/Fe NPs, leading to higher debromination reactivity for BDE47 compared with the bare-Pd/Fe NPs. Therefore Pd/Fe NPs can be utilized as a promising remediation technology for the contaminated groundwater and soils. [Mh] Termos MeSH primário: Bromo/química Celulose/química Éteres Difenil Halogenados/química Ferro/química Nanopartículas Metálicas/química Paládio/química [Mh] Termos MeSH secundário: Recuperação e Remediação Ambiental/métodos Derivados da Hipromelose/química Nanopartículas Metálicas/ultraestrutura Microscopia Eletrônica de Varredura Estrutura Molecular Peso Molecular Tamanho da Partícula Espectroscopia Fotoeletrônica Polímeros/química Espectroscopia de Infravermelho com Transformada de Fourier Difração de Raios X [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (Halogenated Diphenyl Ethers); 0 (Polymers); 0 (polyanions); 0N97R5X10X (2,2',4,4'-tetrabromodiphenyl ether); 3NXW29V3WO (Hypromellose Derivatives); 5TWQ1V240M (Palladium); 9004-34-6 (Cellulose); E1UOL152H7 (Iron); SBV4XY874G (Bromine) [Em] Mês de entrada: 1709 [Cu] Atualização por classe: 170906 [Lr] Data última revisão: 170906 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170330 [St] Status: MEDLINE [do] DOI: 10.1371/journal.pone.0174589

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[PMID]: 28202264 [Au] Autor: Duan L; Cheng N; Xiu G; Wang F; Chen Y [Ad] Endereço: State Environmental Protection Key Lab of Environmental Risk Assessment and Control on Chemical Processes, East China University of Science and Technology, Shanghai 200237, China. [Ti] Título: Characteristics and source appointment of atmospheric particulate mercury over East China Sea: Implication on the deposition of atmospheric particulate mercury in marine environment. [So] Source: Environ Pollut;224:26-34, 2017 May. [Is] ISSN: 1873-6424 [Cp] País de publicação: England [La] Idioma: eng [Ab] Resumo: Total Suspended Particulate (TSP) samples were collected at Huaniao Island in northern East China Sea (ECS) from March 2012 to January 2013. Chemical analysis were conducted to measure the concentration of total particulate mercury (TPM) and speciated particulate mercury including HCl-soluble particulate mercury (HPM), elemental particulate mercury (EPM) and residual particulate mercury (RPM). The bromine (Br) and iodine (I) on particles were also detected. The mean concentration of TPM during the study period was 0.23 ± 0.15 ng m , while the obviously seasonal variation was found that the concentrations of TPM in spring, summer, fall and winter were 0.34 ± 0.20 ng m , 0.15 ± 0.03 ng m , 0.15 ± 0.05 ng m and 0.27 ± 0.26 ng m , respectively. The statistically strong correlation of bromine and iodine to HPM was only found in spring with r = 0.81 and 0.77 (p < 0.01), respectively. While the strongest correlations between EPM and bromine and iodine were found in winter with r = 0.92 (Br) and 0.96 (I) (p < 0.01), respectively. The clustered 72-h backward trajectories of different seasons and the whole sampling period were categorized into 4 groups. In spring, the clusters passed a long distance across the East China Sea and brought about low concentration of mercury due to the deposition of mercury over the sea. The cluster of air mass across the sea had low concentration of HPM in winter, which suggested that the oxidation of mercury in winter might be related to other oxidants. During the whole sampling period, the air mass from the north of China contributed to the higher concentration of TPM in Huaniao Island. [Mh] Termos MeSH primário: Poluentes Atmosféricos/análise Monitoramento Ambiental Mercúrio/análise Material Particulado/análise [Mh] Termos MeSH secundário: Bromo/análise China Estações do Ano [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (Air Pollutants); 0 (Particulate Matter); FXS1BY2PGL (Mercury); SBV4XY874G (Bromine) [Em] Mês de entrada: 1705 [Cu] Atualização por classe: 170517 [Lr] Data última revisão: 170517 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170217 [St] Status: MEDLINE

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